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Evidence-based Clinical Chinese Medicine - Volume 7: Insomnia

Evidence-based Clinical Chinese Medicine - Volume 7: Insomnia

Xue Charlie Changli | Lu Chuanjian | Shergis Johannah

(2018)

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Book Details

Table of Contents

Section Title Page Action Price
Contents xxv
Disclamier v
Foreword vii
Purpose of the Monograph xi
Authors and Contributors xv
Members of Advisory Committee and Panel xvii
Professor Charlie Changli Xue, PhD xix
Professor Chuanjian Lu, MD xxi
Acknowledgments xxiii
List of Figures xxxv
List of Tables xxxvii
1. Introduction to Insomnia 1
Definition of Insomnia 1
Epidemiology 2
Burden 2
Risk Factors 2
Diagnosis 3
Differential Diagnosis 4
Pathophysiology of Insomnia 6
Management 7
Pharmacological Management 8
Complementary and Alternative Medicine Therapies 9
Prognosis 9
References 9
2. Insomnia in Chinese Medicine 17
Introduction 17
Aetiology and Pathogenesis 18
Syndrome Differentiation and Treatments 18
Treatment Based on Syndrome Differentiation 19
Depressed Liver Qi Transforming into Fire 21
Internal Harassment of Phlegm-Heat 21
Dual Deficiency of the Heart and Spleen 22
Qi Deficiency of the Heart and Gallbladder 23
Yin Deficiency with Effulgent Fire 23
Non-interaction between the Heart and Kidney 24
Intense Heart Fire 24
Blood Stasis Obstructing the Brain Collateral 25
Stomach Disharmony 25
Manufactured Medicines 26
Acupuncture Therapies 26
Ear Acupuncture 28
Other Chinese Medicine Therapies 29
Other Management Strategies 29
References 30
3. Classical Chinese Medicine Literature 31
Introduction 31
Search Terms 32
Search Procedure and Data Coding 33
Data Analysis Procedure 34
Search Results 35
Frequency of Citations by Dynasty 36
Chinese Herbal Medicine 37
Wen dan tang 温胆汤 39
Citations Related to Insomnia 40
Most Frequent Herbs in Insomnia Citations 40
Acupuncture and Related Therapies 42
Other Chinese Medicine Therapies 42
Classical Literature in Perspective 44
References 44
4. Method of Evaluating Clinical Evidence 47
Introduction 47
Search Strategy 48
Inclusion Criteria 50
Exclusion Criteria 50
Outcomes 50
Risk of Bias Assessment 52
Statistical Analyses 54
Assessment Using GRADE 54
References 56
5. Clinical Evidence for Chinese Herbal Medicine 59
Introduction 59
Previous Systematic Reviews 59
Characteristics of Clinical Studies of Chinese Herbal Medicine 61
Chinese Herbal Medicine Treatments 61
Randomised Controlled Trials of Chinese Herbal Medicine 63
Chinese Herbal Medicine Treatments 64
Risk of Bias 67
Sleep Quality 68
Pittsburgh Sleep Quality Index 68
Athens Insomnia Scale 71
Sleep Dysfunction Rating Scale 72
Self-rating Scale of Sleep 72
Spiegel Sleep Questionnaire 73
Subjective Sleep Parameters 73
Sleep Onset Latency 73
Total Sleep Duration 73
Sleep Efficiency 74
Polysomnography 74
Sleep Onset Latency 74
Total Sleep Duration 74
Wake After Sleep Onset 75
Sleep Efficiency 75
Depression and Anxiety Scales 75
Hamilton Rating Scale for Depression 75
Hamilton Rating Scale for Anxiety 76
Zung’s Self-rating Depression Scale 76
Zung’s Self-rating Anxiety Scale 77
Daytime Functional Impairment 77
Quality of Life 77
Clinician-rated Outcomes 78
Clinician Global Impression-severity 78
Effective Rate 78
Effective Rate Defined by the New Drug Guideline 78
Effective Rate Defined by the Chinese Medicine Standards 79
Assessment Using GRADE 80
Chinese Herbal Medicine vs. Placebo 80
Chinese Herbal Medicine vs. Benzodiazepine Drugs 80
Chinese Herbal Medicine vs. Non-Benzodiazepine Drugs 80
Chinese Herbal Medicine plus Psychotherapy vs. Psychotherapy 86
Randomised Controlled Trial Evidence for Individual Formulae 86
Wen dan tang 温胆汤 86
Suan zao ren tang 酸枣仁汤 86
Subjective sleep quality 86
Clinician-rated outcomes 89
Depression and anxiety scales 89
Xue fu zhu yu tang 血府逐瘀汤 89
Sleep quality 89
Subjective sleep parameters 90
Depression and anxiety scales 90
Clinician-rated outcomes 90
Gui pi tang 归脾汤 90
Sleep quality and subjective sleep parameters 91
6. Pharmacological Actions of the Frequently Used Herbs 143
Introduction 143
Methods 143
Experimental Studies on suan zao ren 酸枣仁 144
Experimental Studies on fu ling 茯苓 145
Experimental Studies on ye jiao teng 夜交藤 146
Experimental Studies on dang gui 当归 146
Experimental Studies on yuan zhi 远志 147
Experimental Studies on chuan xiong 川芎 147
Experimental Studies on dan shen 丹参 148
Experimental Studies on bai shao 白芍 149
Experimental Studies on chai hu 柴胡 149
Experimental Studies on Gan Cao 甘草 150
Summary of Pharmacological Actions of the Common Herbs 150
References 151
7. Clinical Evidence for Acupuncture and Related Therapies 161
Introduction 161
Previous Systematic Reviews 162
Characteristics of Clinical Studies of Acupuncture and Related Therapies 163
Acupuncture Points 165
Chinese Medicine Syndromes 165
Randomised Controlled Trials of Acupuncture and Related Therapies 165
Acupuncture Treatments 166
Risk of Bias 168
Acupuncture 169
Results 170
Pittsburgh Sleep Quality Index 170
Pittsburgh Sleep Quality Index – Individual Domains 170
Athens Insomnia Scale 172
Self-rating Scale of Sleep 172
Spiegel Sleep Questionnaire 172
Polysomnography 172
Beck Anxiety Inventory 173
Hamilton Rating Scale for Depression and Anxiety 173
Zung Self-rating Depression and Anxiety Scale 173
Epworth Sleepiness Scale 174
Short Form Health Survey 174
Chinese Quality of Life Instrument 174
WHO Quality of Life Questionnaire 174
New Drug Guideline 174
Chinese Medicine Standards 175
Adverse Events 175
Assessment Using GRADE 177
Acupuncture vs. Sham/Placebo Acupuncture 177
Acupuncture vs. Benzodiazapine Drugs/Non-Benzodiazapine Drugs 177
Electroacupuncture 177
Scalp Acupuncture 181
Ear Acupuncture 182
Acupuncture plus Ear Acupressure 182
Results 182
Adverse Events 183
Ear Acupressure 183
Results 184
Adverse Events 184
Body Acupressure 184
Results 185
Adverse Events 185
Moxibustion 186
Results 186
Adverse Events 186
Frequently Reported Acupuncture Points in Meta-analyses Showing Favourable Effect 186
Controlled Clinical Trials of Acupuncture and Related Therapies 190
Results 190
Acupuncture 190
Ear Acupressure 191
Non-controlled Studies of Acupuncture and Related Therapies 191
Summary of Acupuncture and Related Therapies Clinical Evidence 192
References 195
8. Clinical Evidence for Other Chinese Medicine Therapies 207
Introduction 207
Characteristics of Clinical Studies of Other Chinese Medicine Therapies 208
Randomised Controlled Trials of Other Chinese Medicine Therapies 208
Risk of Bias 208
Tuina 推拿 210
Cupping 210
Roller Needle 211
Non-controlled Studies of Other Chinese Medicine Therapies 211
Summary of Other Chinese MedicineClinical Evidence 212
9. Clinical Evidence for Combination Therapies 215
Introduction 215
Characteristics of Clinical Studies of Combination Therapies 216
Risk of Bias 218
Combination Therapies Results 219
Chinese Herbal Medicine plus Acupuncture 219
Adverse Events 220
Chinese Herbal Medicine plus Ear Acupressure 220
Adverse Events 222
Acupuncture plus Tuina 222
Adverse Events 223
Chinese Herbal Medicine Footbath plus Other Therapies 223
10. Summary and Conclusions 233
Introduction 233
Chinese Herbal Medicine 234
Chinese Herbal Medicine: Clinical Trial Evidence 234
Individual Chinese Herbal Formulae 238
Acupuncture and Related Therapies 238
Acupuncture and Related Therapies: Clinical Trial Evidence 240
Individual Acupuncture Therapies 241
Other Chinese Medicine Therapies and Combination Therapies 242
Other Chinese Medicine Therapies: Clinical Trial Evidence 243
Conclusions 243
Implications for Practice 243
Implications for Research 244
References 245
Glossary 247
Index 265