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Pediatrics for Medical Graduates

Pediatrics for Medical Graduates

Dr. Arun Babu Thirunavukkarasu

(2018)

Additional Information

Book Details

Abstract

This book is specifically designed to cover undergraduate syllabus and to help medical students preparing for various internal assessment, and university theory exams in Pediatrics. This book will help to understand the basics, will provide you the exact content required during MBBS course. This book has a perfect mix of conceptual and factual elements along with tables and figures to help in easy understanding and retention.

  • Includes all topics from ‘Must know’ areas prescribed in syllabus from leading medical universities of India
  • Includes topics from frequently asked questions in various previous year university theory examinations in Pediatrics
  • The content is given in a simple, concise, point-wise format for easy reading and retention.
  • Bulleted points, bold fonts for important keywords, tables, figures, flow charts and coloured clinical images to enhance the reading experience and revision.
  • Recent evidence-based concepts, latest guidelines, and management algorithms are included.
  • Content is thoroughly peer-reviewed independently by subject experts.
  • Free access to online supplementary materials from MedEnact which includes chapter wise MCQs and previous year paediatrics final MBBS theory questions

Table of Contents

Section Title Page Action Price
Cover Cover
Title Page iii
Copyright Page iv
Dedication v
Foreword vii
Preface ix
Acknowledgments xi
Contents xiii
Chapter 1 - Growth and development 1
1.1 - Growth 1
1.2 - Factors affecting growth 1
1.3 - Laws of growth 2
1.4 - Assessment of physical growth 2
1.5 - Dentition 5
1.6 - Bone age assessment 6
1.7 - Growth charts 6
1.8 - Growth velocity (height velocity) 7
1.9 - Short stature 7
1.10 - Familial Short Stature 9
1.11 - Constitutional growth delay 10
1.12 - Psychosocial dwarfism 10
1.13 - Tall stature 10
1.14 - Failure to thrive (FTT) 10
1.15 - Obesity 11
1.16 - Microcephaly 12
1.17 - Macrocephaly 13
1.18 - Development 13
1.19 - Rules of development 13
1.20 - Factors affecting development 13
1.21 - Development milestones 14
1.22 - Developmental assessment 15
1.23 - Red flag signs in child development 17
1.24 - ‘Development assessment’ tests 17
Online supplementary materials: 17
Chapter 2 - Adolescence and behavioral disorders 18
2.1 - Adolescence 18
2.2 - Stages of adolescence 18
2.3 - Changes during adolescence 18
2.4 - Emotional and social changes 18
2.5 - Important Health problems during adolescence 19
2.6 - Sequence of changes in puberty 19
2.7 - Tanner staging/Sexual maturity rating (SMR) 19
2.9 - Temper tantrums 20
2.10 - Breath holding spells 20
2.11 - Tics 21
2.12 - Tourette syndrome (Gilles de la Tourette syndrome) 21
2.13 - Nocturnal enuresis 22
2.14 - Attention deficit hyperactivity disorder (ADHD) 22
2.15 - Stuttering 23
2.16 - Pervasive developmental disorders (PDD) 23
2.17 - Autism spectrum disorders (ASDs) 23
2.18 - Autism 24
2.19 - Asperger syndrome 25
2.20 - Rett syndrome 25
Online supplementary materials: 25
Chapter 3 - Fluid, electrolytes, and acid base disturbances 26
3.1 - Fluid homeostasis 26
3.1.1 - Total body water (TBW) 26
3.1.2 - Fluid compartments 26
3.1.3 - Osmolality 26
3.1.4 - Regulation of osmolality and volume 26
3.1.5 - Maintenance requirements 28
3.2 - Hyponatremia 28
3.3 - Hypernatremia 30
3.4 - Potassium 32
3.4.1 - Hypokalemia 32
3.4.2 - Hyperkalemia 33
3.5 - Hypocalcemia 34
3.6 - Acid base disturbances 35
3.6.1 - Metabolic acidosis 35
3.6.2 - Metabolic alkalosis 36
Online supplementary materials: 38
Chapter 4 - Nutrition 39
4.1 - Breastfeeding 39
4.1.1 - Types of breast milk 39
4.1.2 - Advantages of breastfeeding 39
4.1.3 - Nutritional composition of breast milk 40
4.1.4 - Breastfeeding—position and attachment 40
4.2 - The 10 steps to successful breastfeeding 41
4.3 - Baby-friendly hospital initiative 41
4.4 - Complementary feeding 41
4.5 - Protein energy malnutrition (PEM) 42
4.5.1 - Etiology of PEM 42
4.5.2 - PEM—indicators and assessment 42
4.5.3 - Classification of PEM 43
4.5.4 - Severe Acute Malnutrition (SAM) 43
4.5.5 - Theories of PEM evolution 43
4.5.6 - Clinical Features of PEM 43
4.6.1 - Kwarshiorkor (edematous malnutrition) 44
4.6.2 - Marasmus (non-edematous malnutrition) 44
4.6.3 - Management of Severe Malnutrition: 45
4.6.4 - Ready to use therapeutic food (RUTF) 47
4.6.5 - Nutritional recovery syndrome (Refeeding syndrome) 47
4.7 - Vitamin deficiencies 47
4.7.1 - Vitamin A deficiency 47
4.7.2 - Nutritional Rickets 49
4.7.3 - Vitamin E deficiency 50
4.7.4 - Vitamin K deficiency 50
4.7.5 - Thiamine deficiency 51
4.7.6 - Riboflavin Deficiency 51
4.7.7 - Niacin deficiency (Vitamin B3) 51
4.7.8 - Vitamin B6 deficiency 52
4.7.9 - Vitamin B12 deficiency 52
4.7.10 - Vitamin C deficiency (Scurvy) 52
Online supplementary materials: 54
Chapter 5 - Fetal and neonatal medicine 55
5.1 - Fetal assessment and prenatal diagnosis 55
5.1.1 - Assessment of gestational age 55
5.1.2 - Prenatal diagnosis of fetal disease 55
5.1.3.1 - Cell free fetal DNA in the maternal circulation 56
5.1.3 - Fetal size and growth rate abnormalities 56
5.1.3.1 - Fetal growth restriction (FGR) 56
5.1.3.2 - Macrosomia 57
5.1.4 - Antepartum assessment of fetal well-being 57
5.1.4.1 - Fetal movement count 57
5.1.4.2 - The nonstress test (NST) 57
5.1.4.3 - Contraction stress test (CST) 57
5.1.4.4 - Biophysical profile (BPP)– 58
5.1.4.5 - Doppler ultrasonography of fetal vessels 58
5.1.5 - Indications for antepartum fetal surveillance 58
5.1.6 - Intrapartum assessment of fetal well-being 59
5.1.6.1 - Parameters of the fetal heart rate that are evaluated include 59
5.1.6.2 - Fetal blood gas analysis 59
5.2 - Important terminologies and definitions in neonatology 59
5.3 - Neonatal resuscitation 60
5.4 - Birth injuries 62
5.4.1 - Cephalohematoma 62
5.4.2 - Caput succedaneum 63
5.4.3 - Subaponeurotic hemorrhage/subgaleal bleed 63
5.4.4 - Brachial palsy 64
5.4.5 - Clavicle fracture 65
5.5 - Infant of diabetic mother 65
5.6 - Hypothermia 65
5.7 - Kangaroo mother care 66
5.8 - Neonatal jaundice 67
5.9 - Hemorrhagic Disease of Newborn (Vitamin K deficiency bleeding) 70
5.10 - Neonatal Sepsis 71
5.11 - Respiratory diseases 73
5.11.1 - Respiratory Distress Syndrome 73
5.11.2 - Transient Tachypnea of Newborn (TTNB) 74
5.11.3 - Meconium Aspiration Syndrome (MAS) 75
5.11.4 - Apnea 75
5.12 - CNS disorders 76
5.12.1 - Neonatal Seizures 76
5.12.2 - Hypoxic Ischemic Encephalopathy (HIE) 76
5.13 - Transient metabolic disorders 77
5.13.1 - Hypoglycemia 77
5.13.2 - Hyperglycemia 78
5.13.3 - Hypocalcemia 78
5.14 - Surgical Diseases of Newborn 79
5.14.1 - Congenital diaphragmatic hernia (CDH) 79
5.14.2 - Necrotizing Enterocolitis (NEC) 79
Online supplementary materials: 80
Chapter 6 - Genetics 81
6.1 - Introduction 81
6.2 - Types of genetic disorders 81
6.3 - Autosomal dominant inheritance 81
6.4 - Autosomal recessive inheritance 82
6.5 - X-Linked recessive inheritance 82
6.6 - X-Linked dominant inheritance 82
6.7 - Multifactorial/polygenic inheritance 83
6.8 - Mitochondrial disorders 84
6.9 - Genomic imprinting 84
6.10 - Uniparental disomy 84
6.11 - Down syndrome (Trisomy 21) 84
6.12 - Edward syndrome 86
6.13 - Patau syndrome 87
6.14 - Klinefelter syndrome 87
6.15 - Turner syndrome 88
6.16 - Genetic counselling 88
Online supplementary materials: 89
Chapter 7 - Metabolic disorders 90
7.1 - Approach to a child with suspected metabolic disorder presenting with intractable seizures and hypoglycemia 90
7.2 - Phenylketonuria (PKU) 92
7.3 - Tyrosinemia 92
7.4 - Albinism 93
7.5 - Alkaptonuria 93
7.6 - Homocystinuria 94
7.7 - Maple syrup urine disease 95
7.8 - Galactosemia 95
7.9 - Hereditary fructose intolerance 96
7.10 - Approach to a child with glycogen storage disorder 96
7.11 - Von-Gierke disease 97
7.12 - Approach to muco-polysaccharidoses (MPS) 98
7.13 - Gaucher disease 100
7.14 - Abetalipoproteinemia 101
7.15 - Alpha 1 antitrypsin deficiency 101
7.16 - Wilson disease 101
Online supplementary materials: 102
Chapter 8 - Immunology and allergy 103
8.1 - Classification of types of immunity 103
8.2 - Immunodeficiency diseases 103
8.3 - Investigations for a child with suspected immunodeficiency 104
8.4 - Defects in innate immunity 104
8.4.1 - Leukocyte adhesion defect (LAD) 104
8.4.2 - Chediak–Higashi syndrome (CHS) 104
8.4.3 - Myeloperoxidase (MPO) deficiency 105
8.4.4 - Chronic granulomatous disease (CGD) 105
8.5 - Defects in adaptive immunity 106
8.5.1.1 - X-linked agammaglobulinemia (XLD) 106
8.5.1.2 - Common variable immunodeficiency (CVID) 106
8.5.1.3 - Hyper-IgM syndrome 107
8.5.1.4 - Selective IgA deficiency 107
8.5.2.1 - Severe combined immunodeficiency (SCID) 107
8.5.2.2 - Ataxia telangiectasia 107
8.5.2.3 - Wiskott–Aldrich syndrome 108
8.5.2.4 - Hyper IgE syndrome (Job syndrome) 108
8.5.3.1 - DiGeorge syndrome 108
8.6 - Intravenous immunoglobulin 109
Allergic diseases 109
8.8 - Systemic anaphylaxis 110
8.9 - Bronchial asthma 110
8.10 - Status asthmaticus 114
8.11 - Exercise induced bronchoconstriction 115
Online supplementary materials: 116
Chapter 9 - Rheumatology 117
9.1 - Approach a child with suspected arthritis 117
Musculoskeletal examination 118
9.2 - Juvenile idiopathic arthritis (JIA) 118
9.3 - Systemic lupus erythematosus (SLE) 120
9.4 - Juvenile dermatomyositis 122
9.5 - Vasculitis 123
Kawasaki disease 123
9.5.2 - Takayasu arteritis 124
9.5.3 - Polyarteritis nodosa 125
Online supplementary material: 125
Chapter 10 - Infectious diseases 126
10.1 - Approach to a child with fever 126
10.2 - Fever without focus 128
10.3 - Pyrexia of unknown origin 129
10.4 - Bacterial Infections 130
10.4.1 - Pertussis 130
10.4.2 - Staphylococcal infections 131
10.4.3 - Enteric fever (Typhoid fever) 132
10.4.4 - Diphtheria 134
10.4.5 - Scrub typhus 135
10.4.6 - Tetanus 136
10.4.7 - Leptospirosis 137
10.4.8 - Tuberculosis (TB) 138
10.5 - Viral infections 141
10.5.1 - Infectious mononucleosis 141
10.5.2 - Measles 142
10.5.3 - Mumps 143
10.5.4 - Varicella 144
10.5.5 - HIV in children 145
10.5.6 - Dengue 147
10.6 - Malaria 150
10.7 - Vaccines 152
10.7.1 - Types of vaccines 152
10.7.2 - Cold Chain 153
10.7.3 - National Immunization schedule 153
10.7.4 - Bacillus Calmette Guerin (BCG) Vaccine 154
10.7.5 - Hemophilus influenzae B vaccine 154
10.7.6 - Pentavalent Vaccine 154
10.7.7 - Mumps Measles Rubella (MMR) 155
10.7.8 - Rotavirus Vaccine 155
10.7.9 - Rabies vaccine 155
10.7.10 - Meningococcal Vaccine 156
10.7.11 - Cholera Vaccines 156
10.7.12 - Hepatitis B Vaccine 156
10.7.13 - Varicella vaccine 157
10.7.14 - Typhoid vaccine 157
10.7.15 - Hepatitis A vaccine 157
10.7.16 - Pneumococcal vaccine 157
Online supplementary materials: 157
Chapter 11 - Hematology 158
11.1 - Approach to a child with anemia 158
11.2 - Causes of microcytic hypochromic anemia 159
11.3 - Causes of macrocytic hypochromic anemia 159
11.4 - Causes of normocytic normochromic anemia 159
11.5 - Iron deficiency anemia 160
11.6 - Megaloblastic anemia 161
11.7 - Approach to child with suspected hemolytic anemia 162
11.8 - Hereditary spherocytosis (HS) 163
11.9 - Glucose-6-phosphate dehydrogenase deficiency (G6PD Deficiency) 164
11.10 - Autoimmune hemolytic anemia (AIHA) 165
11.11 - Thalassemia 166
11.12 - Sickle cell anemia 168
11.13 - Aplastic anemia 169
11.14 - Hematopoietic stem cell transplant (HSCT) 170
11.15 - Approach to a bleeding child 170
11.16 - Idiopathic thrombocytopenic purpura (ITP) 171
11.17 - Hemophilia 172
11.18 - Disseminated intravascular coagulation (DIC) 172
11.19 - Approach to child with thrombosis 174
11.20 - Eosinophilia 174
Online supplementary materials: 175
Chapter 12 - Gastrointestinal System 176
12.1 - Idiopathic hypertrophic pyloric stenosis 176
12.2 - Gastroesophageal reflux disease (GERD) 177
12.3 - Acute watery diarrhea 178
12.4 - Dysentery 181
12.5 - Persistent diarrhea 181
12.6 - Chronic diarrhea 183
12.7 - Intussusception 184
12.8 - Choledochal cyst 185
12.9 - Malabsorption 185
12.10 - Inflammatory bowel disease 186
12.11 - Gastroschisis 187
12.12 - Duodenal Atresia 187
12.13 - Exomphalos (Omphalocele) 187
12.14 - Hirschsprung disease (congenital aganglionic megacolon) 188
12.15 - Anorectal Anomalies 189
12.16 - Approach to a Child with upper gastrointestinal bleeding 190
12.17 - Approach to a child with lower gastrointestinal bleeding 191
12.18 - Liver abscess 191
12.19 - Acute viral hepatitis 192
12.20 - Chronic hepatitis B 193
12.21 - Fulminant hepatic failure 193
12.22 - Chronic liver disease 195
22.23 - Ascites 196
22.24 - Spontaneous bacterial peritonitis 197
22.25 - Portal hypertension 198
Online supplementary materials: 199
Chapter 13 - Cardiovascular system 200
13.1 - Fetal circulation 200
13.2 - Acyanotic congenital heart disease (ACCHD) 201
13.3 - Atrial septal defects (ASD) 202
13.4 - Ventricular septal defect (VSD) 204
13.5 - Patent ductus arteriosus (PDA) 205
13.6 - Cyanotic congenital heart disease (CCHD) 207
13.7 - Tetralogy of fallot (TOF) 207
13.8 - Transposition of the great arteries (TGA) 210
13.9 - Tricuspid atresia 211
13.10 - Total anomalous pulmonary venous return (TAPVR) 212
13.11.1 - Mitral stenosis 213
13.11.2 - Mitral regurgitation (MR) 214
13.11.3 - Aortic stenosis (AS) 215
13.11.4 - Aortic regurgitation (AR) 216
13.12 - Acute rheumatic fever (ARF) 218
13.13 - Congestive cardiac failure (CCF) 221
13.14 - Hypertension 222
13.15 - Infective endocarditis (IE) 223
13.16 - Acute pericarditis 226
13.17 - Cardiac arrhythmia 227
13.18 - Supra ventricular tachycardia (SVT) 227
13.19 - Coarctation of aorta (CoA) 228
13.20 - Cardiovascular involvement in systemic diseases 229
13.21 - Miscellaneous cardiac conditions 230
Online supplementary materials: 230
Chapter 14 - Respiratory system 231
14.1 - Acute bronchiolitis 231
14.2 - Acute tonsillopharyngitis 232
14.3 - Acute laryngotracheobronchitis (CROUP) 233
14.4 - Epiglottitis (Supra-glottitis) 234
14.5 - Pneumonia 235
14.5.1 - Pneumococcal pneumonia 238
14.5.2 - Staphylococcal pneumonia 238
14.5.3 - Atypical pneumonia 239
14.6 - Foreign body aspiration 239
14.7 - Lung abscess 240
14.8 - Bronchiectasis 241
14.9 - Cystic fibrosis 243
14.10 - Empyema 243
Chapter 15 - Nephrology 245
15.1 - Glomerulonephritis 245
15.2 - Acute glomerulonephritis/acute nephritic syndrome 245
15.3 - Post streptococcal glomerulonephritis 245
15.4 - Rapidly progressive (Crescentic) Glomerulonephritis (RPGN) 247
15.5 - Henoch-schonlein purpura (HSP) nephritis 248
15.6 - Hemolytic uraemic syndrome (HUS) 250
15.7 - IgA nephropathy (berger’s disease) 251
15.8 - SLE nephritis (Lupus Nephritis) 251
15.9 - Approach to hematuria 252
15.10 - Nephrotic syndrome 253
15.10.1 - Minimal change disease/steroid sensitive nephrotic syndrome 253
15.10.2 - Steroid resistant nephrotic syndrome 256
15.11 - Renal tubular acidosis 257
15.12 - Urinary tract infection 258
15.13 - Vesico uretric reflux (VUR) 259
15.14 - Acute renal failure 260
15.15 - Chronic kidney disease (previously known as chronic renal failure) 262
15.16 - Renal replacement therapies (RRT) 263
15.17 - Polycystic kidney disease 264
15.7.1 - Autosomal recessive polycystic kidney disease 264
15.7.2 - Autosomal dominant polycystic kidney disease 264
15.18 - Posterior urethral valve 264
Online supplementary materials: 265
Chapter 16 - Neurology 266
16.1 - Neural tube defects (NTD) 266
16.2 - Hydrocephalus 267
16.3 - Vein of Galen Malformation 269
16.4 - Posterior Fossa Anomalies 269
16.4.1 - Dandy-walker syndrome 269
16.4.2 - Arnold Chiari Malformation 269
16.5 - Seizures 270
16.6 - Febrile seizures 270
16.7 - Absence seizures (Petitmal seizures) 272
16.8 - Status epilepticus 272
16.9.1 - Neurofibromatosis 274
16.9.2 - Tuberous sclerosis (TSC) 275
16.9.3 - Sturge-Weber syndrome 276
16.10 - Raised intracranial tension 276
16.11 - Pseudotumor Cerebri (Idiopathic Intracranial Hypertension) 277
16.12 - Cerebral palsy 278
16.13 - Mental retardation/Intellectual disability 280
16.14 - Acute bacterial meningitis/pyogenic meningitis 281
16.15 - Tuberculous meningitis 282
16.16 - Viral meningoencephalitis 283
16.17 - Brain abscess 284
16.18 - Subacute sclerosing pan-encephalitis 285
16.19 - Sydenham’s chorea 285
16.20 - Disorders of neuromuscular system 285
16.20.1 - Guillian-barre syndrome 285
16.20.2 - Myasthenia Gravis 286
16.20.3 - Infant Botulism 286
16.20.4 - Duchenne Muscular Dystrophy 287
16.20.5 - Bell’s palsy 288
Online supplementary materials: 288
Chapter 17 - Endocrinology 289
17.1 - Growth hormone deficiency (GHD) 289
17.2 - Diabetes insipidus (DI) 290
17.3 - Diabetes mellitus (DM) 291
17.4 - Hypothyroidism 294
17.4.1 - Congenital hypothyroidism (CH) 294
17.4.2 - Acquired hypothyroidism 295
17.5 - Neonatal Grave’s disease 296
17.6 - Hyperthyroidism 296
17.6.1 - Graves’ Disease 296
17.7 - Hypoparathyroidism 297
17.8 - Cushing syndrome 298
17.9 - Adrenal insufficiency 299
17.10 - Congenital adrenal hyperplasia 300
17.11 - 21-Hydroxylase deficiency 301
Online supplementary materials: 302
Chapter 18 - Pediatric oncology 303
18.1 - Acute lymphoblastic leukemia (ALL) 303
18.2 - Acute myeloid leukemia (AML) 306
18.3 - Chronic myeloid leukemia (CML) 309
18.4 - Hodgkin lymphoma 310
18.5 - Non-hodgkin leukemia 311
18.6 - Retinoblastoma 313
18.7 - Neuroblastoma 314
18.8 - Rhabdomyosarcoma 316
18.9 - Brain tumors 316
18.9.1 - Astrocytoma 316
18.9.2 - Medulloblastoma 317
18.9.3 - Craniopharyngioma 317
18.10 - Childhood histiocytosis 317
18.11 - Wilms tumor 318
Online supplementary materials: 320
Chapter 19 - Dermatology 321
19.1 - Skin physiology 321
19.2 - Benign skin lesions in newborn 321
19.2.1 - Acrocyanosis 321
19.2.2 - Cutis marmorata 321
19.2.3 - Harlequin color change 321
19.2.4 - Erythema toxicum neonatorum (ETN) 322
19.2.5 - Subcutaneous fat necrosis of the newborn 322
19.2.6 - Mongolian spots 322
19.2.7 - Miliaria 322
19.2.8 - Milia 323
19.3 - Scabies 324
19.4 - Pediculosis 324
19.5 - Atopic dermatitis 324
19.6 - Molluscum contagiosum 325
19.7 - Diaper dermatitis 325
19.8 - Pyoderma 326
19.9 - Epidermolysis bullosa 327
19.10 - Steven johnson syndrome 327
19.11 - Toxic epidermal necrolysis 328
19.12 - Staphylococcal scalded skin syndrome 328
19.13 - Acrodermatitis enteropathica 329
19.14 - Ichthyosis 329
19.15 - Hemangioma 330
Online supplementary materials: 331
Chapter 20 - Poisoning and envenomation 332
20.1 - Poisoning 332
20.2 - Paracetamol poisoning 335
20.3 - Kerosene poisoning 336
20.4 - Lead poisoning (Plumbism) 337
20.5 - Iron poisoning 338
20.6 - Snake bite 339
20.7 - Scorpion sting 342
Online supplementary materials: 344
Chapter 21 - Social pediatrics 345
21.1 - Diarrhoea control programme 345
21.2 - Acute respiratory infection (ARI) control programme 346
21.3 - Reproductive and child health programme 348
21.4 - IMNCI (integrated management of neonatal and childhood illness) 348
21.5 - Acute flaccid paralysis (AFP) surveillance 350
21.6 - Child neglect and abuse 351
21.7 - Adoption 351
21.8 - National Rural Health Mission 352
21.9 - Nutritional programmes related to child health 353
Online supplementary materials: 354
Index 355