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Physiology: Prep Manual for Undergraduates

Physiology: Prep Manual for Undergraduates

Vijaya D Joshi | Sadhana Joshi Mendhurwar

(2018)

Additional Information

Book Details

Abstract

Salient Features

  • Systemize presentation of text in Question-Answer format helps in revision and self-assessment before examination
  • Extensively revised, updated, and strengthened to keep up with the latest changes in the standard books of physiology
  • Thoroughly revised topics like blood; nerve and muscle; cardiovascular system; and central nervous system
  • Large number of diagrams, tables and flowcharts to facilitate quick learning and greater retention of knowledge

Table of Contents

Section Title Page Action Price
Front Cover Cover
Front matter iii
Physiology Prep Manual for Undergraduates Sixth Edition iii
Copyright iv
Dedication v
Foreword vii
Preface to the sixth edition ix
Preface to the first edition x
1 The cell and general physiology 1
Cell and cell organelles 1
Cell division 2
Cell death 4
Homeostasis 4
Transport across cell membrane 7
Simple diffusion 8
Facilitated diffusion 9
Active transport 11
Primary active transport 11
Mechanism of pump (fig. 1.6): 11
Secondary active transport 12
Mechanism of cotransport 12
Mechanism of countertransport 13
Pinocytosis and phagocytosis 13
Osmosis and osmotic pressure* 14
Resting membrane potential 15
2 Blood 18
Body fluids 18
Measurements of volumes of different fluids 19
Blood 22
Blood volume 23
Blood pH 25
Plasma proteins 25
Nonprotein nitrogenous substances 28
Blood cells 28
Haemopoiesis – formation of blood cells 28
Red blood cells 28
Haemoglobin 32
Metabolism of B₁₂ 34
Metabolism of iron 34
Anaemia 35
Polycythaemia 38
Lifespan and fate of RBC 38
Fragility 39
ESR 39
Jaundice 40
White blood cells 41
Formation of WBCs 44
Abnormalities 46
Platelets 48
Clotting of blood 50
Anticoagulants 54
Diseases 55
Methods for determination of defects in blood clotting 56
Clot lysis 56
Blood groups 57
Blood transfusion 58
Rh blood group system 60
Lymphatic system 61
3 Immunity 65
Introduction 65
Classification 65
Nonspecific immunity 65
Specific immunity 66
Humoral immunity 67
Cell-mediated immunity 70
Factors affecting resistance to infection 72
Allergy 73
AIDS 73
4 Digestion and absorption 75
Introduction 75
Gastrointestinal tract (GI tract) 75
Mastication 76
Salivary glands 77
Deglutition 80
Anatomy of stomach 82
Functions of stomach 82
Motor functions 82
Control of pyloric sphincter 84
Vomiting 85
Secretory function 86
Small intestine 93
Structure 93
Secretion 94
Movements 95
Pancreas 96
Bile 98
Large intestine 102
Digestion and absorption 104
5 Excretory system 109
Introduction 109
Structure of nephron 109
Blood flow to kidneys 111
Formation of urine 112
Glomerular filtration 113
Reabsorption 117
Secretion 120
Tubular load, tubular maximum 120
Plasma clearance 122
Formation of dilute or concentrated urine 124
Regulation of electrolyte balance 126
Regulation of pH of body fluids 129
Renal function tests 133
Micturition 134
Dialysis 136
6 Temperature regulation 137
Introduction 137
Mechanisms of heat production 137
Mechanisms of heat loss 138
Regulation of body temperature 139
Abnormalities in temperature regulation 142
Skin and its functions 142
7 Respiratory system 144
Introduction 144
Pulmonary circulation 146
Mechanism of respiration 148
Pulmonary pressures 150
Intrapleural pressure 150
Intra-alveolar pressure 153
Transpulmonary pressure 153
Applied aspect 153
Compliance 154
Applied aspect 155
Work of breathing 155
Ventilation 156
Dead space air 161
Alveolar ventilation 163
VA/Q ratio 163
Applied aspect 165
Diffusion of gases 166
Respiratory membrane 166
Factors affecting diffusion of gases 166
Diffusing capacity of lungs 168
Transport of gases 168
Transport of oxygen 168
Transport of carbon dioxide 172
Respiratory exchange ratio 174
Applied aspect 175
Regulation of respiration 175
Nervous regulation 176
Chemical regulation 178
Periodic breathing 180
Important respiratory reflexes 181
Receptors in the airway 181
Terms used for altered respiration 182
Hypoxia 183
Acclimatization 185
Mountain sickness 186
Hyperbaric oxygen therapy 186
Cyanosis 186
Artificial respiration 187
Exposure to low atmospheric pressure 187
Exposure to high atmospheric pressure 188
Cardiorespiratory changes during exercise 188
8 Special senses 192
Vision 192
Eye 192
Aqueous humour 194
Vitreous humour 195
Refraction 195
Errors of refraction 197
Accommodation 199
Visual acuity 201
Depth perception 202
Retina 203
Receptors 204
Photochemistry of rods 205
Photochemistry of cones (colour vision) 207
Dark and light adaptation 208
Neuronal connections in retina 210
Visual pathway 212
Field of vision 215
Muscles of eye and eye movements 218
Pupillary reflexes 219
Horner syndrome 220
Hearing 220
Introduction 220
Structure and functions of external (outer) and middle ear 221
Structure and functions of inner ear (cochlea) 223
Auditory pathway 228
Deafness 230
Taste 232
Smell 234
Equilibrium 236
Structure and functions of vestibular apparatus 236
Vestibular pathway 239
Nystagmus 240
Vestibular function tests 240
9 Endocrinology 241
Introduction 241
Hormones 242
Anterior pituitary gland 245
Growth hormone 246
Posterior pituitary gland 248
Thyroid gland 250
Actions of thyroid hormones 251
Regulation of thyroid hormones 254
Thyroid function tests 255
Applied 255
Adrenal cortex and medulla 257
Adrenal medullary hormones 257
Applied 260
Adrenocortical hormones 260
Mineralocorticoids: 261
Regulation 262
Glucocorticoids 263
Regulation 264
Other hormones 266
Applied 266
Pancreas 267
Insulin 268
Actions of insulin 268
Regulation 270
Applied 271
Glucagon 273
Actions of glucagon 273
Regulation 273
Somatostatin 273
Parathyroid 274
Calcium and phosphate metabolism 274
Composition and formation of bone 275
Parathyroid hormone 277
Actions 277
Regulation 278
Vitamin D 278
Calcitonin 278
Control of calcium ion concentration 279
Tetany 279
Hypercalcaemia 280
Hypoparathyroidism and hyperparathyroidism 280
Rickets 280
Osteomalacia 281
Osteoporosis 281
10 Reproduction 282
Male reproductive system 282
Male sex organs 282
Spermatogenesis 282
Seminal vesicles and prostate 285
Semen 286
Capacitation 286
Fertilization of ovum 286
Effect of temperature on spermatogenesis 287
Hormones of testis 287
Puberty and male climacteric 289
Female reproductive system 290
Female sex organs 290
Hormones 291
Menstrual cycle 291
Ovarian hormones 291
Pregnancy 299
Parturition 303
Lactation 303
Circulatory changes at birth 304
Contraception 305
11 Nerve and muscle 307
Nerve 307
Introduction and classification 307
Stimulus 308
Initiation of action potential 309
Propagation of action potential 309
Recording of action potential 311
Properties of nerve fibre 314
Degeneration of nerve 316
Reaction of degeneration 317
Muscle 317
Introduction 317
Structure of skeletal muscle 318
Excitation–contraction coupling 321
Muscle contraction 321
Energetics of muscle contraction 324
Muscle tension 325
Types of skeletal muscle fibres 327
Properties of skeletal muscle 328
Tetanus 329
Fatigue 330
Common terms used 330
EMG 332
Neuromuscular junction 333
Structure 333
Transmission of impulse 334
Drugs affecting neuromuscular junction 334
Myasthenia gravis 335
Muscle rigour 335
Functions of skeletal muscles 335
Comparison of skeletal, cardiac and smooth muscles 336
Smooth muscle 340
12 Cardiovascular system 342
Introduction 342
Cardiac muscle 343
Initiation and conduction of cardiac impulse 344
Applied aspect 349
Nervous control of heart rhythm 349
Cardiac cycle 350
Heart sounds 355
Electrocardiogram 357
Abnormalities in rate and rhythms* 363
Haemodynamics 364
Pulse 369
Venous system 369
Capillary system 370
Control of blood flow 372
Nervous control of blood flow 374
Blood pressure 375
Vasomotor centre 375
Short-term mechanisms regulating blood pressure 377
Long-term mechanisms regulating blood pressure 381
Cardiac output 382
Shock 384
Regulation of blood flow through skeletal muscle 387
Heart rate 387
Cardiac failure* 388
Coronary circulation 390
Cerebral circulation 393
Pulmonary circulation 394
13 Central nervous system 395
Introduction 395
Levels of CNS function 395
Types of cells in nervous system 396
Nerve-fibres classification 397
Synapse 397
Definition 398
Types 398
Structure 398
Synaptic transmission 399
EPSP 400
IPSP 400
Properties of synapse 401
Neurotransmitters 404
Important neurotransmitters 404
Sensory system 405
Introduction 405
Classification of sensations 406
Receptors 406
Classification 406
Properties 407
Receptor potential 409
Cutaneous sensations 409
Sensory pathway 410
Ascending tracts 410
Physiology of pain 414
Reflexes 419
Classification 419
Properties of reflex action 421
Important reflexes 422
Stretch reflex 422
Applied aspect 426
Golgi tendon reflex 426
Withdrawal reflex 427
Difference in monosynaptic and polysynaptic reflex 427
Spinal cord 427
Spinal reflexes 429
Motor system 430
Introduction 430
Descending tracts 431
Pyramidal (corticospinal tract) 431
Extrapyramidal tracts 432
Difference between lateral and medial motor systems 435
Difference between pyramidal and extrapyramidal systems 435
Transection of spinal cord 436
Brainstem 438
Muscle tone 440
Abnormalities 442
Posture and equilibrium 443
Decorticate preparation 446
Hypothalamus 446
Structure 446
Connections 447
Functions 448
Limbic system 450
Reticular formation 451
Thalamus 453
Structure 453
Connections 454
Functions 455
Applied aspect 455
Basal ganglia 455
Structure 455
Connections 456
Functions 459
Effects of damage* 460
Cerebellum 461
Structure 461
Connections 463
Structural unit 465
Functions* 466
Cerebellar damage* 468
Cerebral cortex 468
Structure 468
Control of voluntary movements 470
Frontal lobe 470
Connections and functions 470
Occipital lobe 475
Index 489
A 489
B 490
C 490
D 492
E 492
F 493
G 493
H 494
I 495
J 495
L 495
M 496
N 496
O 497
P 497
Q 498
R 498
S 499
T 500
U 501
V 501
W 502
Z 502