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Evidence-based Clinical Chinese Medicine - Volume 4: Adult Asthma

Evidence-based Clinical Chinese Medicine - Volume 4: Adult Asthma

Xue Charlie Changli | Lu Chuanjian | Shergis Johannah

(2018)

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Book Details

Table of Contents

Section Title Page Action Price
Contents xxv
Disclaimer v
Foreword vii
Purpose of the Monograph xi
Authors and Contributors xv
Members of Advisory Committee and Panel xvii
Professor Charlie Changli Xue, PhD xix
Professor Chuanjian Lu, MD xxi
Acknowledgments xxiii
List of Figures xxxiii
List of Tables xxxv
1. Introduction to Asthma 1
Definition of Asthma 1
Prevalence 2
Risk Factors 2
Pathological Processes 3
Diagnosis 4
Diagnostic Assessment 4
Differential Diagnosis 6
Other Diagnostic Considerations 6
Acute Exacerbations of Asthma 7
Management 7
Pharmacological Treatments 7
Reliever Medications 9
Controller Medications 9
Other Medications 11
Non-pharmacological Interventions 11
Prognosis 11
References 12
2. Asthma in Chinese Medicine 15
Introduction 15
Aetiology and Pathogenesis 15
Syndrome Differentiation and Treatments 17
Chinese Herbal Medicine Treatment Based on Syndrome Differentiation 19
Chronic Asthma (Stable Stage) 19
Lung-Spleen Qi Deficiency 19
Lung-Kidney Deficiency 20
Single Herb Formula 21
Acute Exacerbations of Asthma (Acute Stage) 21
Cold Wheezing 21
Heat Wheezing 22
Wind Wheezing 23
Phlegm Wheezing 23
Weak Wheezing 24
Wheezing Collapse 24
Acupuncture Therapies and Other Chinese Medicine Therapies 25
Other Management Strategies 26
References 26
3. Classical Chinese Medicine Literature 29
Introduction 29
Classical Literature Search 30
Search Procedure and Data Coding 31
Data Analysis Procedure 31
Search Results 32
Search Terms 33
Frequency of Citations by Dynasty 35
Asthma Symptoms 37
Chinese Herbal Medicine 38
Most Frequent Herbs in Classical Literature Citations 38
Chinese Herbal Medicine Citations Related to Asthma 38
Acupuncture and Related Therapies 41
Acupuncture Citations Related to Asthma 41
Chinese Herbal Medicine and Acupuncture 42
Other Chinese Medicine Therapies 43
Classical Literature in Perspective 43
References 44
4. Method of Evaluating Clinical Evidence 47
Introduction 47
Search Strategy 48
Inclusion Criteria 49
Exclusion Criteria 51
Outcomes 51
Risk of Bias Assessment 52
Statistical Analyses 54
Assessment Using GRADE 55
References 56
5. Clinical Evidence for Chinese Herbal Medicine 59
Introduction 59
Previous Systematic Reviews 60
Characteristics of Chinese Herbal Medicine Clinical Studies 60
Randomised Controlled Trials of Chinese Herbal Medicine 62
Risk of Bias 67
Outcomes 68
Chronic Asthma 68
Lung Function 68
Health-related Quality of Life 70
Asthma Control 70
Exacerbation Frequency 70
Use of Rescue Medication 71
Effective Rate 71
Assessment Using GRADE: Chronic Asthma 73
Randomised Controlled Trial Evidence from Individual Formula and Formula Commonly Used in Clinical Practice 73
Assessment Using GRADE 73
Frequently Reported Herbs in Meta-Analyses Showing Favourable Effect 78
Acute Exacerbations of Asthma 78
Lung Function 78
Health-related Quality of Life 83
Asthma Control 83
Use of Rescue Medication 83
Effective Rate 83
Assessment Using GRADE: Acute Exacerbations of Asthma 85
Randomised Controlled Trial Evidence from Individual Formula and Formula Commonly Used in Clinical Practice 85
Assessment Using GRADE 88
Frequently Reported Herbs in Meta-Analyses Showing Favourable Effect 92
Safety of Chinese Herbal Medicine in Randomised Controlled Trials 92
Controlled Clinical Trials of Chinese Herbal Medicine 93
Lung Function 94
Health-related Quality of Life 94
Asthma Control 94
Use of Rescue Medication 95
Effective Rate 95
Safety of Chinese Herbal Medicine in Controlled Clinical Trials 95
Non-controlled Studies of Chinese Herbal Medicine 96
Safety of Chinese Herbal Medicine in Non-controlled Studies 96
Summary of Chinese Herbal Medicine Clinical Evidence 97
References 99
References to Included Chinese Herbal Medicine Studies 99
6. Pharmacological Actions of the Frequently Used Herbs 121
Introduction 121
Experimental Studies on ma huang 麻黄 122
Experimental Studies on gan cao 甘草 122
Experimental Studies on xing ren 杏仁 122
Experimental Studies on ban xia 半夏 123
Experimental Studies on di long 地龙 123
Experimental Studies on zi su zi 紫苏子 123
Experimental Studies on huang qin 黄芩 124
Experimental Studies on wu wei zi 五味子 125
Experimental Studies on xi xin 细辛 125
Experimental Studies on huang qi 黄芪 125
Summary of Pharmacological Actions of the Common Herbs 126
References 126
7. Clinical Evidence for Acupuncture and Related Therapies 131
Introduction 131
Previous Systematic Reviews 132
Characteristics of Clinical Studies of Acupuncture and Related Therapies 132
Randomised Controlled Trials of Acupuncture and Related Therapies 135
Risk of Bias 137
Acupuncture 137
Effects of the Intervention: Acupuncture 138
Electroacupuncture 139
Assessment Using GRADE: Acupuncture 139
Moxibustion 139
Effects of the Intervention: Moxibustion 142
Acupressure 142
Acupoint Magnet Therapy 143
Laser Acupuncture 144
Scalp Acupuncture 144
Frequently Reported Acupuncture Points in Meta-analyses Showing Favourable Effect 144
Controlled Clinical Trails of Acupunture and Related Therapies 144
Non-controlled Studies of Acupuncture and Related Therapies 144
Summary of Acupuncture and Related Therapies Clinical Evidence 146
References 147
References to Included Acupunture and Related Therapies Studies 147
8. Clinical Evidence for Other Chinese Medicine Therapies 151
Introduction 151
Previous Systematic Reviews 152
Characteristics of Clinical Studies of Other Chinese Medicine Therapies 152
Randomised Controlled Trials of Other Chinese Medicine Therapies 152
Risk of Bias 154
Cupping Therapy 154
Controlled Clinical Trials of Other Chinese Medicine Therapies 154
Non-controlled Clinical Studies of Other Chinese Medicine Therapies 154
Summary of Other Chinese Medicine Clinical Evidence 155
References 155
References to Included Other Chinese Medicine Therapies 155
9. Clinical Evidence for Combination Therapies 157
Introduction 157
Characteristics of Clinical Studies of Combination Therapies 159
Risk of Bias 159
Chinese Herbal Medicine plus Electroacupuncture 159
Herbal Wash plus Plum-blossom Needle 159
Summary of Evidence from Combination Therapies 160
References Included Combination Therapies Studies 160
10. Summary and Conclusions 161
Introduction 161
Chinese Herbal Medicine 162
Findings from Chinese Herbal Medicine Clinical Trials 162
Chronic Asthma 163
Acute Exacerbations of Asthma 164
Acupuncture and Related Therapies 165
Findings from Clinical Trials of Acupuncture and Related Therapies 166
Acupuncture 167
Moxibustion 167
Other Chinese Medicine Therapies 167
Implications for Practice 168
Implications for Research 169
References 170
Glossary 171
Index 183