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Organ Histology - A Student's Guide

Organ Histology - A Student's Guide

Hinrichsen Colin

(1997)

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Book Details

Abstract

This book is a concise but comprehensive text for review and self evaluation in the study of the microscopic anatomy of the major organ systems of the body. It aims to meet the requirements of students of Medicine, Dentistry, Histopathology, Mammalian Biology and the Paramedical Sciences. The subjects have been chosen to complement a program of physiology and dissection or prosection. Basic concepts of cell and tissue biology are presently considered in separate prerequisite units integrated with biochemistry and genetics and are not included in this text. The approach has been to focus on unique features or diagnostic differences between cells, their function and organisation into organs rather than on pure morphologic description. Developmental aspects of certain organs have been described where these contribute to understanding functional relationships between cells in organ systems.A uniform text structure (point form) helps the reader to organise, review and retain pertinent information. A summary procedes each chapter which helps to focus on key concepts. Each topic is also prefaced by a list of objectives which serve as a guide for review. In addition, a list of key words (bold in the text), phrases and concepts that should be defined as a result of reading the text. The terminology follows that in contemporary use giving alternative names according to Nomina Histological where possible. A series of plates illustrates in line drawings the major features of cells in organs based on electron micrographs. In addition, tables show functional relationships between cells or their products.

Table of Contents

Section Title Page Action Price
Contents vii
Preface v
Chapter 1 INTEGUMENTARY SYSTEM 1. SKIN 1
OBJECTIVES 1
CHAPTER OUTLINE 1
Skin 1
KEYWORDS, PHRASES, CONCEPTS 2
1. General 3
2. Functions of Skin 3
3. Physical Examination of Skin 4
4. Fingerprints (Dermatoglyphics) 4
5. Epidermis 5
6. Development of the Epidermis 9
7. The Dermal-Epidermal Junction 9
8. Dermis 12
9. Vascular Supply of the Dermis 12
10. Hypodermis (Subcutaneous Layer or Superficial Fascia) 13
11. Nerve Supply 13
Chapter 2 INTEGUMENTARY SYSTEM 2. SKIN APPENDAGES 17
OBJECTIVES 17
CHAPTER OUTLINE 17
Eccrine Sweat Glands 17
Hair 18
Nails 18
KEY WORDS, PHRASES, CONCEPTS 18
ECCRINE SWEAT GLANDS 19
1. General 19
2. Detailed Structure 19
3. Sweat 20
4. Development of Sweat Glands 20
5. Apocrine Sweat Glands 21
HAIR 21
1. General 21
2. Detailed Structure 22
3. Functions of Hair 23
4. Development of Hair 24
5. Associated Muscle and Glands 24
NAILS 25
1. General 25
2. Detailed Structure 25
3. Function of Nails 26
4. Development of Nails 26
5. Growth of Nails 27
Chapter 3 ENDOCRINE SYSTEM 1. HYPOPHYSIS, DIFFUSE NEUROENDOCRINE AND CHROMAFFIN SYSTEMS 29
OBJECTIVES 29
CHAPTER OUTLINE 29
Characteristics of Endocrine Glands 29
KEY WORDS, PHRASES AND CONCEPTS 30
1. General 31
2. Development of the Hypophysis 32
3. General Structure 33
4. Detailed Structure 34
6. Hypothalamic Regulation of the Adenohypophysis 36
8. Neurohypophysis 37
9. Hormones Released by the Neurohypophysis 38
10. Blood Supply of the Hypophysis 38
11. Histophysiology of the Hypophysis 39
12. The Diffuse Neuroendocrine System (Amine Precursor Uptake and Decarboxylation or Apud Cells) 40
13. The Chromaffin System 40
Chapter 4 ENDOCRINE SYSTEM 2. THYROID, PARATHYROID AND ENDOCRINE PANCREAS 43
OBJECTIVES 43
CHAPTER OUTLINE 44
— Thyroid Gland 44
— Parathyroid Glands 44
— Pancreas 44
KEY WORDS, PHRASES AND CONCEPTS 45
THE THYROID GLAND 45
1. Development 45
2. General Structure 47
3. Detailed Structure 47
4. Histophysiology 49
PARATHYROID GLANDS 50
1. General 50
2. Detailed Structure 51
3. Histophysiology 53
THE PANCREAS 53
1. General 53
2. Development 54
3. Cells of Pancreatic Islets 54
4. Blood Supply of the Pancreas 56
5. Hormones of the Pancreatic Islets 57
6. Control of Islet Secretion 58
7. Histophysiology 60
8. Exocrine Pancreas 60
Chapter 5 ENDOCRINE SYSTEM 3. SUPRARENAL GLANDS 61
OBJECTIVES 61
CHAPTER OUTLINE 61
The Suprarenal Glands 61
Effects of Suprarenel medulla ACTH 62
KEY WORDS, PHRASES AND CONCEPTS 62
1. General Structure 62
2. Development 63
3. Detailed Structure of the Suprarenal Cortex 63
4. Blood Supply of the Suprarenal Cortex 64
5. Histophysiology of the Suprarenal Cortex 64
SUPRARENAL MEDULLA 67
1. General Structure 67
2. Detailed Structure 67
3. Histophysiology of the Medulla 67
4. The Chromaffin System 68
CHAPTER 6 IMMUNE SYSTEM 1. CELLS OF THE IMMUNE RESPONSE 93
OBJECTIVES 71
CHAPTER OUTLINE 71
KEY WORDS, PHRASES, CONCEPTS 72
1. General 73
2. Terminology 73
3. Lymphocytes 74
4. Origin of Lymphocytes 78
5. Plasma Cells 79
6. Immune Responses 81
7. Circulation of Lymphocytes 81
8. Macrophages (Histiocytes) 82
9. Antigen Presenting Cells (APC) 84
10. Mast Cells 84
11. Polymorphonuclear Leucocytes or Granulocytes(Polymorphs) 85
CHAPTER 7 IMMUNE SYSTEM 2. LYMPH, LYMPH VESSELS, LYMPH NODES AND TONSILS 93
OBJECTIVES 93
CHAPTER OUTLINE 94
Lymph. 94
KEY WORDS, PHRASES AND CONCEPTS 94
1. Lymph 95
2. Lymph Vessels 95
3. Movement of Lymph 96
4. Methods of Studying Lymph Vessels 96
5. Edema 97
6. Lymph Nodes 97
7. Gut Associated Lymphoid Tissue (Galt) 101
8. Tonsils 102
Chapter 8 IMMUNE SYSTEM 3. THYMUS AND SPLEEN 105
OBJECTIVES 105
CHAPTER OUTLINE 105
Thymus 105
Spleen 106
KEY WORDS, PHRASES, CONCEPTS 106
THE THYMUS 107
1. Development of the Thymus 107
2. General Structure 107
3. Tissue Components 108
4. Blood Supply 109
5. Fate of T Lymphocytes 110
6. Functions of Thymus 110
7. Involution of the Thymus 112
THE SPLEEN 112
1. Development 112
2. Structure 112
3. Blood Circulation Through the Spleen 114
4. Functions of the Spleen 115
5. Effects of Splenectomy 116
CHAPTER 9 CARDIOVASCULAR SYSTEM 119
OBJECTIVES 119
CHAPTER OUTLINE 119
KEY WORDS, PHRASES, CONCEPTS 120
THE CIRCULATORY SYSTEM 121
1. General Functions and Composition of the Circulatory System 121
2. Cardiac Muscle 122
3. Structure of the Heart Wall 123
4. Valves of the Heart 124
5. The Cardiac Cycle 125
6. The Impulse Conducting System 125
7. Basic Organization of Blood Vessels above Precapillaries 126
8. Tissue Components of Vascular Wall 127
9. Arteries 129
10. Capillaries 131
11. Arteriovenous Anastomoses 133
12. Post-Capillary (Pericytic) Venules 133
13. Muscular Venules 133
14. Small and Medium Sized Veins 134
15. Large Veins 134
16. Vasa Vasora 134
17. Valves 134
Chapter 10 RESPIRATORY SYSTEM 1. THE UPPER AIRWAY 135
OBJECTIVES 135
CHAPTER OUTLINE 135
KEY WORDS, PHRASES, CONCEPTS 136
1. General 136
2. Nasal Cavities 137
3. Vascularization of Respiratory Mucosa 138
4. Development of the Nasal Cavities 139
5. Larynx (Larynx (Gk) A Throat) 140
6. Trachea 143
Chapter 11 RESPIRATORY SYSTEM 2. THE LUNGS 147
OBJECTIVES 147
CHAPTER OUTLINE 147
KEY WORDS, PHRASES, CONCEPTS 148
1. General 148
2. Bronchi 150
3. Bronchioles 151
4. Respiratory Bronchioles 152
5. Alveolar Ducts 152
6. Atria 153
7. Alveoli 153
8. The Air-Blood Interface 154
9. Pulmonary Circulation 154
10. Nerve Supply 155
11. Development of the Lungs 155
Chapter 12 DIGESTIVE SYSTEM 1. ORAL CAVITY 159
OBJECTIVES 159
CHAPTER OUTLINE 159
KEY WORDS, PHRASES, CONCEPTS 160
THE ORAL CAVITY 161
1. General 161
2. Lip (Lippa (Anglo-saxon) Lip also Labium (L) a Lip) 162
3. Cheek 162
4. Gingiva (Gingivae (L) Gums) 162
5. Tongue (Lingua (L) the Tongue also Glossa (Gk) the Tongue) 163
6. Development of the Tongue 167
7. The Hard Palate 168
8. The Soft Palate (Velum Palatinum from Velum (L) a Curtain) 169
9. Salivary Glands 169
10. Control of Salivary Gland Function 173
11. Development of the Oral Cavity 173
12. Development of Salivary Glands 175
Chapter 13 DIGESTIVE SYSTEM 2. TEETH 177
OBJECTIVES 177
CHAPTER OUTLINE 177
KEY WORDS, PHRASES, CONCEPTS: 178
1. General 179
2. Enamel 180
3. Dentin 182
4. Cementum 183
5. Pulp 185
6. Periodontal Ligament 186
7. Development of Teeth 189
8. Tooth Eruption 193
9. Exfoliation 195
Chapter 14 DIGESTIVE SYSTEM 3. ESOPHAGUS AND STOMACH 197
OBJECTIVES 197
CHAPTER OUTLINE 198
Esophagus. 198
KEY WORDS, PHRASES, CONCEPTS 198
THE ESOPHAGUS 199
1. General 199
2. Detailed Structure 199
3. Blood Supply of the Esophagus 201
4. Nerve Supply 201
5. Development 202
THE STOMACH 202
1. General 202
2. Detailed Structure 203
3. Functions of the Stomach 206
4. Development 209
Chapter 15 DIGESTIVE SYSTEM 4. INTESTINES 211
OBJECTIVES 211
CHAPTER OUTLINE 212
Intestines 212
KEY WORDS, PHRASES, CONCEPTS 212
INTESTINES 213
1. General Structural Plan of the Gastrointestinal Tract 213
2. Development 215
SMALL INTESTINE 217
1. General Features of the Small Intestine 217
2. Detailed Structure and Function 217
3. Changes in the Small Intestine along Its Length 221
4. Immune Defense Mechanisms 221
5. Absorption 222
6. Further Development of the Midgut 223
LARGE INTESTINE 225
1. General Features 225
2. Regional Details 225
3. Mucosa 227
4. Nerve Supply of the Large Intestine 227
5. Development of the Hindgut 228
6. Functions of the Large Intestine 229
Chapter 16 Digestive System 5. Digestive Glands 233
OBJECTIVES 233
CHAPTER OUTLINE 234
Liver 234
Gall Bladder 234
The Exocrine Pancreas 234
KEY WORDS, PHRASES, CONCEPTS 234
THE LIVER 235
1. General 235
2. General Structure 236
3. Detailed Structure 237
4. Sinusoids 237
5. Bile Ducts 238
6. Structural Units of the Liver 238
7. Functions of the Liver 239
8. Development of the Liver 240
GALL BLADDER 242
1. General 242
2. Detailed Structure 242
3. Functions of the Gall Bladder 243
THE EXOCRINE PANCREAS 243
1. General 243
2. Detailed Structure 243
3. Regulation of Secretion 244
4. Development of the Duct System 244
5. Structure of the Duct System 245
Chapter 17 URINARY SYSTEM 1. KIDNEY 249
OBJECTIVES 249
CHAPTER OUTLINE 249
KEY WORDS, PHRASES, CONCEPTS 250
1. General 251
2. General Structure 251
3. Development 252
4. Detailed Structure 255
5. Blood Supply 259
6. Further Functions of the Kidney 260
Chapter 18 URINARY SYSTEM 2. RENAL PELVIS, CALYCES, URETER, BLADDER AND URETHRA 263
OBJECTIVES 263
CHAPTER OUTLINE 263
KEY WORDS, PHRASES, CONCEPTS 264
RENAL PELVIS, CALYCES AND URETER 264
1. General Structure 264
2. Ureters 265
3. The Bladder 266
4. Male Urethra 267
5. Female Urethra 268
6. Urination (Micturition) 269
7. Development of Bladder and Urethra 270
Chapter 19 MALE REPRODUCTIVE SYSTEM 1.THETESTIS 273
OBJECTIVES 273
CHAPTER OUTLINE 273
KEY WORDS, PHRASES, CONCEPTS 274
1. General 275
2. Testes. General 275
3. Detailed Structure. Seminiferous Epithelium 276
4. Spermatogenesis 277
5. Cycles of Seminiferous Epithelium 280
6. Sertoli cells 280
7. Interstitial cells (of Leydig) 281
8. Boundary layers of seminiferous tubules comprise: 283
9. Factors Influencing Testicular Function 283
10. Development of the Testis 284
Chapter 20 MALE REPRODUCTIVE SYSTEM 2. GENITAL DUCT SYSTEM, ACCESSORY GLANDS AND EXTERNAL GEN ITALIA 317
OBJECTIVES 289
CHAPTER OUTLINE 290
KEY WORDS, PHRASES, CONCEPTS 290
1. Detailed Structure 291
2. Development of the Duct System 293
3. Seminal Vesicles 294
4. Prostate 295
5. Bulbourethral Glands 295
6. Seminal Fluid 296
7. External Genitalia 296
8. Development of Genital Ligaments 297
9. Cryptorchidism (Undescended Testis) 297
10. Penis 297
11. Development of the External Genitalia 299
Chapter 21 FEMALE REPRODUCTIVE SYSTEM 1. OVARY 317
OBJECTIVES 303
CHAPTER OUTLINE 303
KEY WORDS, PHRASES, CONCEPTS 304
1. General 305
2. General Structure of the Ovary 306
3. Oogenesis 306
4. Interstitial cells (Interstitiocytes) 309
5. Hilum cells 309
6. Ovulation 309
7. Corpus Luteum (Luteal Gland) 310
8. Blood Supply of the Ovary 311
9. Nerve Supply 311
10. Lymphatics 311
11. Hormonal Background of the Ovarian Cycle 311
12. Development of the Ovary 313
Chapter 22 FEMALE REPRODUCTIVE SYSTEM 2. UTERINE TUBES, UTERUS AND VAGINA 317
OBJECTIVES 317
CHAPTER OUTLINE 317
Uterine tubes 317
The Uterus 317
KEY WORDS, PHRASES, CONCEPTS 318
UTERINE TUBES 319
1. General 319
2. Detailed Structure 319
3. Functions of the Uterine Tubes 320
THE UTERUS 321
1. General 321
2. Peritoneal Relationships 321
3. Myometrium 321
4. Mucosa (Endometrium or Tunica Mucosa) 322
5. The Menstrual Cycle 323
6. Cervix 325
7. Functions of the Uterus 326
8. Vagina 326
9. Development of the Uterine Tubes, Uterus and Vagina 328
Chapter 23 FEMALE REPRODUCTIVE SYSTEM 3. EXTERNAL GENITALIA AND MAMMARY GLANDS 331
OBJECTIVES 331
CHAPTER OUTLINE 331
External genitalia 331
Mammary glands 332
KEY WORDS, PHRASES, CONCEPTS 332
1. General 332
2. Development of the External Genitalia 334
MAMMARY GLANDS 334
1. General 334
2. Detailed Structure 335
3. Endocrine and Neural Control of the Mammary Gland 337
4. Development 337
Chapter 24 FEMALE REPRODUCTIVE SYSTEM 4. PLACENTA 339
OBJECTIVES 339
CHAPTER OUTLINE 340
KEY WORDS, PHRASES, CONCEPTS 340
THE PLACENTA 341
1. General 341
2. Processes Prior to Fertilization 341
3. Fertilization 343
4. Cleavage 344
5. The Implantation Period 344
6. The Lacunar Stage of Placental Development 345
7. The Trabecular Stage of Placental Development 346
8. Development of Villi 346
9. Decidua (Endometrium) 347
10. Structure of the Placenta 348
11. Blood Supply of the Placenta 348
12. Structure of the Full Term Placenta 349
13. Functions of the Placenta 349
THE UMBILICAL CORD 350
1. General 350
2. Detailed Structure 351
Chapter 25 THE EYE 353
OBJECTIVES 353
CHAPTER OUTLINE 353
KEY WORDS, PHRASES, CONCEPTS 354
THE EYE 355
1. Development of the Optic Cup and Lens Vesicle 355
2. Development of the Retina, Iris and Ciliary Body 356
3. The Cornea 357
4. Sclera 357
5. Limbus (Sclerocorneal Junction) 358
6. The Anterior Chamber 358
7. The Posterior Chamber 358
8. The Uvea 359
9. The Lens 361
10. The Ciliary Zonule or Suspensory Ligament of the Lens 361
11. Vitreous Body (Humor) 361
12. Retina 362
13. Macula Lutea and Fovea Centralis 367
14. Optic Papilla (Optic Disc or Nerve Head) 367
15. Retinal Vessels 367
16. Optic Nerve 368
Chapter 26 THE EAR 369
OBJECTIVES 369
CHAPTER OUTLINE 370
KEY WORDS, PHRASES, CONCEPTS 370
THE EAR 371
1. General 371
2. The External Ear 372
3. The Middle Ear 374
4. The Internal Ear 376
Index 391