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Vascular and Endovascular Surgery E-Book

Vascular and Endovascular Surgery E-Book

Ian Loftus | Robert J. Hinchliffe

(2018)

Additional Information

Book Details

Abstract

Vascular and Endovascular Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities.

For this Sixth Edition the authorship team across the series has been expanded to include additional European and World experts, with an increased emphasis on global practice. Throughout all six volumes the contents have been extensively revised in line with recently published evidence. Detailed supportive key references are provided and are also included within the comprehensive list of references in the accompanying ebook. Links to recommended online videos have been added where appropriate.

  • The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within the major sub-specialties of general surgery.
  • Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter.

Vascular surgery is developing at a rapid pace, especially in the field of medical therapy and endovascular interventions. This new edition aims to put these developments into context, and give a balanced view with regard to technological advances and more traditional techniques. Vascular and endovascular practitioners will find this a very useful resource in their day to day clinical practice.


Table of Contents

Section Title Page Action Price
Front Cover Cover
Inside Front Cover ES2
Vascular and Endovascular Surgery iii
Copyright iv
Contents v
Series Editors’ preface vii
Editors’ preface ix
Acknowledgements ix
Evidence-based practice in surgery xi
Contributors xiii
Chapter 1: Epidemiological risk factors for PAD, risk stratification and risk factor management 1
Introduction 1
Epidemiology of PAD 1
Natural history of PAD: limb-specific, cardiovascular morbidity and mortality 3
Limb-specific outcomes 3
Association of PAD with atherosclerotic disease in other arterial beds 4
Association of PAD with subsequent cardiovascular morbidity and mortality 4
Epidemiological risk factors for PAD, risk stratification and risk factor management (Fig. 1.3) 5
Age and gender 6
Cigarette smoking 6
Diabetes mellitus 6
Blood pressure management (Fig. 1.4) 7
Dyslipidaemia 8
Antiplatelet therapy 10
Conclusions 11
Key references 12
Chapter 2: Assessment of chronic lower limb ischaemia 13
Introduction 13
Intermittent claudication 13
Rare causes of ischaemia 16
Persistent sciatic artery 16
Cystic adventitial disease (CAD) 17
Popliteal artery entrapment 18
Fibromuscular dysplasia (FMD) 18
Endofibrosis of the iliac artery 19
Buerger's disease 19
History and examination 19
History 19
Examination 20
Exercise challenge 20
ABPI measurement using a hand-held Doppler device 21
Toe pressures 22
Risk factors 22
Vascular laboratory 23
Waveform assessment and segmental pressures 23
Transcutaneous oximetry 24
Duplex ultrasound (DUS) 24
Assessment of suprainguinal arteries 26
Assessment of femoro-popliteal segment 26
Radiological investigations 26
Magnetic resonance angiography (MRA) 26
Technique 27
Contraindications 27
Computed tomographic angiography 28
Contrast media 29
Catheter angiography 31
Technique 31
Carbon dioxide (CO2) angiography 32
Chapter 3: Medical treatment of chronic lower limb ischaemia 36
Introduction 36
PAD diagnosis and screening 36
Modifying cardiovascular risk 38
Smoking cessation 38
Treatment of diabetes 39
Additional lifestyle modifications 39
Management of dyslipidaemia 39
Antiplatelet and antithrombotic medications 39
Blood pressure medication 39
Homocysteine-lowering medications 40
Medical treatment for symptomatic PAD 40
Exercise 40
Pharmacologic interventions 40
Naftidrofuryl oxalate 41
Cilostazol 41
Levocarnitine 41
HMG-CoA reductase inhibitors (Statin) 41
Pentoxifylline 41
Ramipril 41
Other medications 41
Intermittent Pneumatic Compression 42
Angiogenesis 42
Conclusions 42
Key references 43
Chapter 4: Intervention for chronic lower limb ischaemia 44
Introduction 44
Presenting symptoms 44
Exercise therapy 44
Medical therapy 45
Global trends toward revascularisation treatment 45
A regional approach to intervention 45
Aorto-iliac occlusive disease 45
Revascularisation of aorto-iliac disease 46
Surgical treatment for aorto-iliac disease 46
Percutaneous treatment for aorto-iliac disease 46
Percutaneous vs open surgery for aorto-iliac occlusive disease revascularisation 47
Angioplasty vs stent vs covered stent 48
Common femoral artery disease 49
Common femoral endarterectomy 49
Profundaplasty 49
Percutaneous treatment for the common femoral artery 50
Superficial femoral artery disease 50
Surgical bypass 50
Percutaneous treatment for the superficial femoral artery 51
Nitinol self-expanding stents 52
Stent grafts 52
Atherectomy 52
Drug-coated balloon angioplasty 52
Drug-eluting stents 52
Surgical bypass vs percutaneous intervention 53
Popliteal artery disease 53
Percutaneous treatment for the popliteal artery 54
Atherectomy 54
Nitinol, self-expanding stents 54
Novel devices for the popliteal artery 54
Infrapopliteal artery disease 54
Surgical bypass for infrapopliteal disease 55
Percutaneous treatment for infrapopliteal disease 55
Percutaneous Transluminal Angioplasty 55
Drug-coated balloon angioplasty 56
Bare-metal stents 56
Drug-eluting stents 56
Choice of revascularisation method for the infrapopliteal arteries 57
The angiosome concept 58
Primary amputation 58
Disclosure 59
Key references 59
Chapter 5: The diabetic foot 62
Introduction 62
Epidemiology 62
Development of foot ulceration 62
Diabetic peripheral neuropathies 62
Diagnosis of neuropathy 63
Peripheral artery disease (PAD) 63
Biomechanical aspects 64
Other risk factors 64
Management 65
The ‘at-risk’ foot 65
Ulcer management 65
Neuropathic ulcers 66
Ischaemic and neuroischaemic ulcers 67
Infection 67
Topical wound healing agents 68
Medical problems on the surgical ward 68
Charcot neuro-osteoarthropathy 69
Key references 70
Chapter 6: Amputation, rehabilitation and prosthetic developments 71
Introduction 71
Epidemiology 71
Indications for amputation 72
Level selection 72
Surgical considerations 73
Transfemoral amputation 74
Through-knee amputation 74
Transtibial amputation 75
Foot amputation 75
Rehabilitation 76
Planning 76
Stump management 76
Pain management 77
Early postoperative rehabilitation 77
Primary prosthetic rehabilitation 77
Sport activities for amputees 78
Prostheses 78
Prosthetic developments 79
Rehabilitation for the bariatric patient 80
Key references 81
Chapter 7: Revision vascular surgery 83
Introduction 83
Graft occlusion 83
Factors influencing graft occlusion 83
Local factors 83
General factors 84
Prevention of graft thrombosis 85
Management of graft stenosis (the failing graft) 85
Management of the occluded (failed) graft 86
Role of thrombolysis 86
Suprainguinal graft thrombosis 87
Infrainguinal graft thrombosis 87
Graft infection 88
Causes 88
Prevention 88
Presentation 88
Bacteriology 89
Diagnosis 89
Management 90
General principles 90
Infrarenal aortic graft infection 90
Graft aneurysms 94
True aneurysms 94
False aneurysms 95
Carotid artery 96
Infection 96
Aneurysm formation 97
Revision after CAS 97
Revision surgery after EVAR 97
Revision surgery after infected EVAR 98
Revision after TEVAR 98
Aortobronchial fistula 98
Aorto-oesophageal fistula 99
Infection 99
Key references 100
Chapter 8: Management of acute lower limb ischaemia 102
Introduction 102
Aetiology 102
Embolism 102
Atheroembolism 103
Thrombosis 103
Other causes 104
Recent changes 106
Clinical features 106
Initial management 107
Revascularisation 107
Irreversible (category III) leg ischaemia 107
Immediately threatened (category IIb ischaemia) 108
Threatened (category IIa ischaemia)/viable (category I ischaemia) 108
Choice between surgery and thrombolysis: the evidence 109
Peripheral artery thrombolysis 110
Contraindications (Box 8.2) 110
Technique 110
Percutaneous thrombectomy devices 112
Complications 112
Outcome 114
Surgical management 114
Balloon catheter embolectomy 114
Completion angiography 116
Failed embolectomy 116
Further management 117
Overall prognosis 117
Conclusions 118
Key references 118
Chapter 9: Vascular trauma 120
Introduction 120
Mechanism of injury 120
Blunt trauma 120
Penetrating trauma 120
Sequelae of vascular injuries 120
Clinical assessment 121
History 121
Examination 121
Diagnosis 123
Resuscitation and initial management 123
Special investigations 123
Plain radiography 123
Angiography 123
Ultrasound 124
General principles of management of vascular injury 124
Venous injuries 125
Endovascular management of vascular trauma 125
Cervical vascular injuries 126
Carotid artery injuries 126
Mechanism 126
Clinical signs 126
Diagnosis 127
Management 127
Operative technique 128
Vertebral artery injuries 128
Subclavian and axillary vascular injuries 128
Endovascular management of cervical vascular injuries 129
Thoracic vascular injuries 129
Clinical presentation and initial management 130
Diagnostic studies 130
Chest radiography 130
Angiography 131
Other imaging modalities 131
Treatment 131
Endovascular repair 131
Surgical repair 131
Abdominal vascular injuries 131
Diagnosis 131
Management 132
Aortic injury 133
Visceral artery injury 133
Renal artery injury 133
Inferior vena cava injury 133
Pelvic vascular injury 134
Extremity vascular trauma 134
Diagnosis 134
General principles of management 134
Vascular injuries to the upper limb (Fig. 9.16) 135
Brachial artery injuries 135
Distal arterial injuries to the upper limb 136
Vascular injuries to the lower limb 136
Femoral vascular injuries 136
Popliteal vascular injury 136
Resuscitative endovascular balloon occlusion of the aorta (REBOA) 137
Chapter 10: Extracranial cerebrovascular disease 140
Introduction 140
Aetiology and risk factors 140
Large-vessel thromboembolism 140
Small-vessel disease 140
Cardiogenic brain embolism 140
Haematological disorders 141
Non-atheromatous carotid diseases 141
Fibromuscular dysplasia (FMD) 141
Arteritis 142
Carotid aneurysm 142
Carotid dissection 142
Carotid body tumour 143
Presentation of carotid disease 144
Asymptomatic cerebrovascular disease 144
Symptomatic cerebrovascular disease 144
Carotid territory 144
Vertebrobasilar 145
Non-hemispheric 145
Investigation of carotid disease severity 145
Duplex ultrasound 145
Catheter angiography 147
Magnetic resonance angiography 147
Computed tomographic angiography (CTA) 147
Comparison of methods 147
Management of cerebrovascular disease 147
Best medical therapy’ 147
Management of carotid disease 149
Symptomatic carotid artery disease 149
Randomised trials comparing CEA with CAS in symptomatic patients 152
New ischaemic lesions on MR imaging 153
Asymptomatic carotid artery disease 153
Comparison of CEA and CAS in randomised trials 154
CEA/CAS and coronary bypass 154
Emergency CEA 156
Vertebral artery revascularisation 156
Surgical management of carotid disease – carotid endarterectomy 156
Anaesthesia 156
Technique 157
Perioperative monitoring and completion assessment 157
Operative complications 158
Cranial nerve injuries 158
Wound complications 158
Perioperative stroke 158
Long-term follow-up and restenosis 159
Patch infection 159
Endovascular treatment of carotid disease 159
Assessing suitability for CAS 159
Dual antiplatelet therapy 160
CAS technique 160
Cerebral protection devices 161
Distal protection devices 161
Distal balloon occlusion 161
Distal filter devices 162
Flow reversal/flow arrest (endovascular clamping) 162
Does stent design influence outcome? 164
Periprocedural haemodynamic problems 164
Haemodynamic depression 164
Hyperperfusion and intracranial haemorrhage 164
Management of post-CAS and CEA stroke 165
Distal embolism 165
Thrombosis 166
Dissection 166
Key references 167
Chapter 11: Vascular disorders of the upper limb 168
Introduction 168
Clinical examination 168
Occlusive disease 168
Brachiocephalic artery 168
Aorto-brachiocephalic bypass 169
Brachiocephalic endarterectomy 169
Endovascular treatment 169
Subclavian artery 170
Carotid–subclavian bypass 170
Carotid transposition 170
Crossover grafts 170
Endovascular treatment 171
Upper arm arteries 173
Lower arm and hand arteries 173
Aneurysmal disease 173
Upper arm artery aneurysms 175
Lower arm and hand artery aneurysms 175
Ulnar artery aneurysm or hypothenar hammer syndrome 175
Upper limb embolism 176
Other causes of acute ischaemia 176
Thoracic outlet syndrome 177
Neurogenic thoracic outlet compression syndrome (N-TOCS) 177
Diagnosis 177
Treatment 177
Transaxillary resection of first rib 177
Arterial thoracic outlet compression syndrome 179
Surgical management 179
Combined supraclavicular and infraclavicular approach 179
Subclavian–axillary vein thrombosis 181
Primary SVT 182
Diagnosis 182
Treatment 182
Secondary SVT 183
Key references 184
Chapter 12: Primary and secondary vasospastic disorders (Raynaud's phenomenon) and vasculitis 187
Introduction 187
Raynaud's phenomenon 187
Pathophysiology 189
Neural mechanisms 189
Vascular mechanisms 189
Intravascular mechanisms 189
Clinical features 189
Investigations 189
Management 190
General measures 190
Drug therapy 191
Calcium channel blockers 191
Other vasodilators 192
Prostaglandins 192
Other treatments 192
Sympathectomy 192
Conclusion 192
Connective tissue diseases 192
Vasculitis 193
Takayasu's arteritis 194
Buerger's disease (thromboangiitis obliterans) 195
Giant cell arteritis 196
Polyarteritis nodosa 197
Small-vessel vasculitis 198
ANCA-associated vasculitis (AAVs) 198
Immune complex-mediated vasculitis 199
Primary cutaneous small-vessel vasculitis 200
Key references 200
Chapter 13: Peripheral and abdominal aortic aneurysms 201
Introduction 201
Epidemiology 201
Pathophysiology 202
Proteolysis 202
Inflammation 202
Biomechanics 202
Genetics 203
Clinical features 203
Screening 203
Diagnosis 204
Principles of management 204
Preoperative assessment 205
Repair of intact abdominal aortic aneurysm 205
Open repair 206
Operative repair of ruptured abdominal aortic aneurysm 206
EVAR 207
Indications and eligibility for EVAR 207
Patient assessment and EVAR technique 208
EVAR-related complications and device failure 208
Endoleak 208
Graft migration and dislocation 209
Kinking and occlusion 209
Other EVAR-related complications 209
Surveillance after EVAR 209
Outcomes after EVAR 210
The future of EVAR 212
Infected aneurysms 214
Mycotic aneurysms 215
Microbial aneurysmal arteritis 215
Clinical features and management principles of infected aneurysms 215
Peripheral aneurysms 215
Iliac aneurysms 215
Common femoral aneurysms 216
True femoral aneurysms 216
False femoral aneurysms 216
Popliteal artery aneurysms 216
Key references 219
Chapter 14: Thoracic and thoraco-abdominal aortic disease 221
Introduction 221
Imaging of the thoracic aorta 221
Thoracic aortic aneurysms (TAAs) 222
Classification and aetiology 222
Incidence, clinical presentation and indications for treatment 223
Technique of surgical repair 223
Endovascular repair of thoracic aneurysms 223
Neurological complications following endovascular thoracic procedures 225
Outcome of treatment 226
Recommendations for practice 226
Thoraco-abdominal aortic aneurysms (TAAAs) 226
Classification and aetiology 226
Incidence, clinical presentation and indications for treatment 226
Technique of surgical repair 227
Results of surgical repair of thoraco-abdominal aneurysms 228
Endovascular repair of thoraco-abdominal aortic aneurysms 228
Results of endovascular repair of TAAA 228
Hybrid visceral revascularisation and endovascular repair of thoraco-abdominal aortic aneurysms 229
Recommendations for practice 230
Thoracic dissection and acute aortic syndrome 231
Pathology, classification and clinical presentations 231
Investigation of suspected acute aortic syndrome 232
Initial management of acute aortic dissection 233
Endovascular management of complicated acute type B thoracic dissection 233
Early management of uncomplicated type B dissection 234
Treatment of chronic type B dissections 234
Management of intramural haematoma and penetrating aortic ulcer 235
Recommendations for practice 235
Traumatic aortic injury (TAI) 235
Recommendations for practice 236
Aorto-oesophageal and aortopulmonary fistula 236
Chapter 15: Disorders of the renal and mesenteric circulation 238
Renal vascular disease 238
Renal artery disease 238
Atherosclerotic renovascular disease 238
Prevalence 238
Definitions 238
Pathophysiology 238
Clinical presentation 239
Diagnosis5,6 239
Management 240
Renal revascularisation 240
Surgical treatment 240
Endovascular treatment 241
Revascularisation versus medical therapy 242
Renal stenting during treatment of aortic aneurysmal disease 242
Renal artery denervation 243
Other renal vascular disorders 244
Renal artery aneurysm 244
Renal trauma 244
Fibromuscular dysplasia 244
Post-transplant renal artery stenosis 244
Mid-aortic syndrome 244
Mesenteric vascular disease 245
Acute thromboembolic occlusion of the superior mesenteric artery 245
Mesenteric ischaemia 246
Chronic mesenteric ischaemia 246
Acute mesenteric venous thrombosis 248
Non-occlusive mesenteric ischaemia 248
Key references 250
Chapter 16: Central venous and dialysis access 251
Introduction 251
Central venous access 251
Indications 251
Methods 251
Complications 251
Temporary dialysis access 252
Methods 252
Complications of CVCs 252
Insertion 252
Catheter dysfunction 252
Catheter-locking solutions 252
Catheter lumen thrombosis 253
Central vein thrombosis 253
Fibrin sheaths 253
Catheter-related infection 253
Permanent dialysis access 254
Access planning 254
Preoperative assessment 254
Duplex ultrasound 255
Venography 255
Primary access 255
Secondary and tertiary access 256
Factors affecting access patency 257
Access failure 258
Failure to mature 258
Stenosis and thrombosis 258
Prevention of access failure 258
Access surveillance 258
Access salvage 258
AVF stenosis 258
AVG stenosis 259
AVF and AVG thrombosis 260
Other access complications 260
Infection 260
Haemorrhage 261
Steal 261
Carpal tunnel syndrome 262
Cardiac failure 262
Venous hypertension and central vein obstruction 262
Aneurysm 263
Cannulation 264
Access in children 264
Key references 264
Chapter 17: Varicose veins 266
Introduction 266
Pathophysiology 266
Normal venous function 266
Chronic venous hypertension 266
Varicose veins 266
Epidemiology and natural history 267
Clinical presentation 268
Thread veins and reticular veins (CEAP C1) 268
Varicose veins (CEAP C2) 268
Oedema and skin changes (CEAP C3–C4) 268
Chronic venous ulceration: healed or active (CEAP C5–C6) 269
Clinical assessment 270
History 270
Patient examination 270
Hand-held Doppler and other bedside tests 270
Venous investigations 270
Colour duplex ultrasound scanning 270
Other venous investigations 271
Treatment 272
Conservative options, medications and compression 272
Conservative options 272
Venoactive drugs and pharmacotherapy 272
Compression stockings and garments 272
Principles of endovenous and surgical interventions 273
Informed consent 273
Endovenous thermal ablation 273
Setting and anaesthesia 274
Technique 274
Endovenous laser ablation (EVLA) 275
Radiofrequency ablation (RFA) 275
Other modalities for thermal ablation 275
Complications 275
Ultrasound-guided foam sclerotherapy (UGFS) 276
Setting and anaesthesia 276
Technique 276
Choice of sclerosant 277
Complications 277
Non-thermal, non-tumescent endovenous modalities 277
Mechanochemical ablation (MOCA) 277
Cyanoacrylate glue closure 277
Traditional surgery for varicose veins 277
Setting and anaesthesia 277
Technique 278
Complications 278
Treatment of recurrent varicose veins 278
Areas of controversy 279
Treatment of incompetent perforating veins 279
Management of varicosities 279
Saphenous preserving interventions 280
Thromboprophylaxis after endovenous procedures 280
Compression after superficial venous interventions 280
Evidence for varicose vein interventions 280
Endovenous thermal ablation 280
Ultrasound-guided foam sclerotherapy 281
Mechanochemical ablation and cyanoacrylate glue closure 281
Choosing between treatment modalities 281
Rationing of varicose vein treatments 282
Atypical varicose veins 282
Vulval and pelvic varices 282
Congenital causes of varicose veins 282
Conclusions 282
Key references 283
Chapter 18: Chronic leg swelling 285
Chronic venous insufficiency (CVI) 285
Clinical features 285
Skin changes 285
Varicose veins 285
Pain 285
Swelling 285
Ulceration 286
Epidemiology 286
Aetiology 286
Macrocirculation 286
Deep and superficial reflux 286
Perforating vein reflux 286
Microcirculation 287
Classification 287
Investigation 287
Hand-held Doppler 288
Duplex scanning 288
Venography 288
Computed tomography venography 288
Magnetic resonance imaging 288
Intravascular ultrasound 288
Functional measurements 288
Ambulatory venous pressure measurement 288
Plethysmography 288
Treatment 288
General measures 288
Graduated elastic compression 289
Intermittent pneumatic compression 290
Laser and electromagnetic therapy 290
Pharmacotherapy 290
Dressings 290
Emollients 290
Oxpentifylline (pentoxifylline) 290
Nutrition 290
Superficial venous intervention 290
Superficial venous surgery 290
Perforating vein surgery 290
Deep venous valvular reconstruction 291
Skin grafting 291
Endovascular management of venous outflow obstruction 291
Venous bypass 291
Preventing the post-thrombotic limb 292
Summary 292
Dependency and inactivity 292
Lymphoedema 292
Aetiology 292
Primary 293
Secondary 294
Presentation 294
History 294
Examination 294
Clinical staging 295
Investigation 295
Duplex ultrasonography 295
Lymphangioscintigraphy (isotope lymphography) 295
Computed tomography 295
Magnetic resonance imaging 296
Interstitial magnetic resonance lymphangiography 296
Fluorescence microlymphangiography 296
Contrast lymphangiography 296
Treatment 296
General measures 296
Manual lymphatic drainage 296
Graduated elastic compression 296
Intermittent pneumatic compression 296
Thermal treatment 297
Complex decongestive physiotherapy (complex physical therapy) 297
Prevention of infection 297
Drugs 297
Surgical treatments 297
Debulking operations 297
Bypass procedures 298
Key references 299
Chapter 19: The acutely swollen leg 301
Introduction 301
Pathophysiology of oedema 301
Medical history 301
Physical examination 302
Differential diagnosis 302
Musculotendinous rupture 302
Baker's cyst 302
Cellulitis and erysipelas 302
Necrotising fasciitis 302
Lymphoedema 303
Bilateral swelling 303
Deep venous thrombosis 303
Pathophysiology of DVT 303
Clinical decision rules 303
Imaging techniques 304
Treatment of DVT 305
Prognosis 306
Iliofemoral deep vein thrombosis 307
Post-thrombotic syndrome 307
Catheter-directed thrombolysis 308
New treatment modalities 308
EKOS endowave 308
Angiojet 309
Other PMT devices 309
The future 309
Chapter 20: Vascular anomalies 312
Introduction 312
Classification 312
Vascular tumours 312
Infantile haemangioma 312
Diagnosis and imaging 314
Complications and structural associations 314
Management 314
Congenital haemangioma 314
Tufted angioma 315
Kaposiform haemangioendothelioma (KHE) 315
Vascular malformations 315
Capillary malformations 315
Salmon patch (naevus simplex; erythema nuchae) 315
Port-wine stains (naevus flameus) 315
Low-flow vascular malformations 316
Low-flow venous malformations (LFVM) 316
Low-flow lymphatic malformations (LFLM) 316
Diagnosis and imaging 317
Management 317
High-flow vascular malformations 318
Diagnosis and imaging: 319
Management 320
Follow-up and outcomes 320
Conclusions 321
Index 323