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Tu Youyou's Journey In The Search For Artemisinin

Tu Youyou's Journey In The Search For Artemisinin

Zhang Wenhu | Wang Manyuan | Yang Lan

(2018)

Table of Contents

Section Title Page Action Price
Contents xiii
Preface vii
Beginning from the Nobel Prize 1
Getting Informed about Winning the Nobel Prize 1
Award Ceremony 2
A Gift from Traditional Chinese Medicine to the World 2
Setting Ambition at a Young Age 5
A Severe Disease 5
On the Origins of Tu Youyou’s Name 6
Turbulence and Disease 7
The Beginning of a Dream 8
Studying at Peking University 11
Entering Peking University 11
Selecting Pharmacognosy 12
The Legendary Professor Lou Zhicen 13
Mentor Lin Qishou 15
Wholeheartedly Moving Forward 17
Beginning of Work 17
Participating in “Traditional Chinese Medicine Training Workshops for Western Medical Doctors” 19
Sacrificing Family for Work 21
Encountering “Project 523” 25
Invitation from Project 523 26
Origin of “Project 523” 26
Significance of “Project 523” 28
Horrible Malaria 31
A Horrible Disease 31
A Mysterious Leaf 32
A Scary Ballad 33
A Bold Inference 33
A Hateful Tyrant 34
History of the Antimalarial Fight 35
Handbook of Prescriptions for Emergency 35
Compendium of Materia Medica 36
A Knocking Brick for the Door of the Qing Dynasty 37
Legend of Cinchona 38
The Discovery of Ross 39
War and Malaria 43
The Battle of Gallipoli 43
World War II 44
The Vietnam War 45
The Sequel to Malaria 46
The Launch of Antimalarial Research 47
Collection of Antimalarial Prescriptions 47
The Indistinct Artemisia Annua L. 48
Firing the First Shot at Malaria 49
A Way Out 50
Inspiration and Success 53
Studying the Ancient Books of Traditional Chinese Medicine 53
Inspiration Piercing through Dark Clouds 54
Specimen 191 57
The New Extraction Scheme 57
Specimen 191 58
Ether with Low Boiling Point 59
Research on Artemisia annua L. 60
Experiments on Laboratory Rats 61
Pharmacodynamic Study 62
The Safety Experiment 62
Personally Testing Efficacy 65
Not Giving Up 65
Taking the Lead for a Personal Drug Trial 66
More Clinical Trials 67
Antimalarial Symphony 71
The Prologue 71
The Setback 72
The Upsurge 73
From Crystal to Drug 75
Extracting Antimalarial Monomer 75
Final Discovery of Artemisinin 77
Breathtaking Clinical Trials 78
A Large Stage in China 79
Unique Artemisinin 81
Kekule and the Benzene Ring 81
New Drug without Nitrogen 82
Terpenoids 83
Three-Dimensional Structure 84
Rectification of the Name of Artemisia annua L. 87
What is Artemisia annua L.? 87
Six Varieties of Artemisia annua L. 88
Each Showing Its Special Prowess 91
Artemisinin 91
Dihydroartemisinin 93
The Popular Artemether 96
Efficient Artesunate 97
Coartem 98
Introduction into Africa 101
Artemisia annua L. Farming 101
Establishment of Pharmaceutical Factories 102
Story of DDT 103
The Humble New Drug 104
Magical COTECXIN 105
Looking for the Discoverer 107
Censure and Dispute 107
Miller’s Search 108
Glory to Tu Youyou 109
Winning the Nobel Prize 111
Behind the Medal 111
Why Her? 112
Epilogue 115