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Osborn's Brain E-Book

Osborn's Brain E-Book

Anne G. Osborn | Gary L. Hedlund | Karen L. Salzman

(2017)

Additional Information

Book Details

Abstract

Comprehensive, visually appealing, and easy to understand, Osborn’s Brain, second edition, by the highly esteemed Dr. Anne G. Osborn, provides a solid framework for understanding the complex subject of brain imaging when studied cover to cover. Almost completely rewritten and featuring 75% new illustrations, it combines essential anatomy with gross pathology and imaging, clearly demonstrating why and how diseases appear the way they do. The most immediate emergent diagnostic topics are followed by nonemergent pathologies, integrating the most relevant information from Dr. Osborn’s entire career of accumulated knowledge, experience, and interest in neuropathology, neurosurgery, and clinical neurosciences.

  • Covers the "must-know" aspects of brain imaging together with spectacular pathology examples, relevant anatomy, and up-to-date techniques in neuroradiology—perfect for radiologists, neuroradiologists, neurosurgeons, and neurologists at all levels
  • Begins with emergent topics such as trauma, nontraumatic hemorrhage, stroke, and vascular lesions, followed by infections, demyelinating and inflammatory diseases, neoplasms, toxic-metabolic-degenerative disorders, and congenital brain malformations
  • Features more than 4,000 stunning, high-resolution radiologic images and medical illustrations, all of which are annotated to describe the most clinically significant features
  • Includes Dr. Osborn’s trademark summary boxes scattered throughout for quick review of essential facts, as well as the most recent and up-to-date references available
  • Helps readers think clearly about diagnoses, types of diagnoses, and the various pathologies that can affect the brain
  • Includes new WHO classifications of brain tumors, new entities including IgG4-related disease and CLIPPERS, new and emerging infectious diseases, and updated insights into brain trauma and brain degeneration

Table of Contents

Section Title Page Action Price
Front\rCover Cover
Osborn‘s Brain: Imaging, Pathology, and Anatomy iii
Copyright iv
Dedications v
Preface vii
Image Contributors ix
Acknowledgments xi
Table of Contents xii
Section 1: Trauma 4
Chapter 1. Trauma Overview 5
Introduction 5
Imaging Acute Head\rTrauma 6
Trauma Imaging: Keys to\rAnalysis 9
Selected References 12
Chapter 2.\rPrimary Effects of CNS Trauma 13
Scalp and Skull Injuries 13
Extraaxial Hemorrhages 21
Parenchymal Injuries 38
Miscellaneous Injuries 48
Selected References 63
Chapter 3.\rSecondary Effects and Sequelae of CNS Trauma 65
Herniation Syndromes 65
Edema, Ischemia, and\rVascular Injury 75
Chronic Effects of CNS Trauma 81
Selected References 87
Section 2:\rNontraumatic Hemorrhage and Vascular Lesions 92
Chapter 4.\rApproach to Nontraumatic Hemorrhage and Vascular Lesions 93
Imaging Hemorrhage and\rVascular Lesions 93
Approach to Nontraumatic\rHemorrhage 96
Approach to Vascular\rDisorders of the CNS 99
Selected References 102
Chapter\r5. Spontaneous Parenchymal Hemorrhage 103
Evolution of Intracranial\rHemorrhage 105
Macrohemorrhages 115
Microhemorrhages 120
Selected References 122
Chapter 6.\rSubarachnoid Hemorrhage and Aneurysms 123
Subarachnoid Hemorrhage 124
Aneurysms 136
Selected References 154
Chapter 7.\rVascular Malformations 155
CVMs With Arteriovenous\rShunting 157
CVMs Without Arteriovenous\rShunting 176
Selected References 194
Chapter 8.\rArterial Anatomy and Strokes 197
Normal Arterial Anatomy and\rVascular Distributions 197
Arterial Infarcts 208
Miscellaneous Strokes 247
Selected References 252
Chapter\r9. Venous Anatomy and Occlusions 253
Normal Venous Anatomy and\rDrainage Patterns 253
Cerebral Venous Thrombosis 260
Venous Occlusion Mimics 273
Selected References 276
Chapter\r10. Vasculopathy 277
Normal Anatomy of the\rExtracranial Arteries 277
Atherosclerosis 281
Nonatheromatous\rVascular Diseases 295
Selected References 323
Section 3:\rInfection, Inflammation, and Demyelinating Diseases 326
Chapter 11.\rApproach to Infection, Inflammation, and Demyelination 327
CNS Infections 328
HIV/AIDS 329
Demyelinating and\rInflammatory Diseases 329
Chapter 12.\rCongenital, Acquired Pyogenic, and Acquired Viral Infections 331
Congenital Infections 331
Acquired Pyogenic\rInfections 346
Acquired Viral Infections 364
Selected References 376
Chapter\r13. Tuberculosis and Fungal, Parasitic, and Other Infections 377
Mycobacterial Infections 377
Fungal Infections 385
Miscellaneous and\rEmerging CNS Infections 407
Selected References 414
Chapter 14.\rHIV/AIDS 417
Overview 417
HIV Infection 418
Opportunistic Infections 426
Neoplasms in HIV/AIDS 444
Selected References 447
Chapter\r15. Demyelinating and Inflammatory Diseases 449
Multiple Sclerosis and Variants 449
Postinfection and\rPostimmunization Demyelination 464
Autoimmune Encephalitis 472
Inflammatory-Like\rDisorders 482
Selected References 491
Section 4:\rNeoplasms, Cysts, and Tumor-Like Lesions 496
Chapter\r16. Introduction to Neoplasms, Cysts, and Tumor-Like Lesions 497
Classification and Grading of CNS\rNeoplasms 497
Intracranial Cysts 506
Selected References 508
Chapter\r17. Astrocytomas 509
General Features of\rAstrocytomas 509
Localized Astrocytomas 512
Diffuse Astrocytomas 527
Selected References 550
Chapter\r18. Nonastrocytic Glial Neoplasms 553
Oligodendrogliomas 553
Ependymal Tumors 559
Choroid Plexus Tumors 568
Other Neuroepithelial\rTumors 576
Selected References 581
Chapter\r19. Neuronal and Glioneuronal Tumors 583
Glioneuronal Tumors 583
Neuronal Tumors 594
Selected References 606
Chapter\r20. Pineal and Germ Cell Tumors 607
Pineal Region Anatomy\rand Histology 608
Pineal Parenchymal Tumors 611
Germ Cell Tumors 619
Other Cell\" Pineal and Pineal\rRegion Neoplasms 630
Selected References 634
Chapter\r21. Embryonal Neoplasms 635
Medulloblastoma 635
Other CNS Embryonal Tumors 643
Malignant Rhabdoid\rTumors 652
Selected References 658
Chapter\r22. Tumors of the Meninges 659
Anatomy of the Cranial Meninges 659
Meningomas 660
Nonmeningothelial\rMesenchymal Tumors 674
Primary Melanocytic Lesions 686
Other Related Neoplasms 688
Selected References 692
Chapter\r23. Cranial Nerves and Nerve Sheath Tumors 695
Cranial Nerve Anatomy 695
Schwannomas 708
Neurofibromas 723
Malignant Nerve Sheath\rNeoplasms 726
Selected References 730
Chapter\r24. Lymphomas and Hematopoietic and Histiocytic Tumors 731
Lymphomas and Related\rDisorders 731
Histiocytic Tumors 750
Hematopoietic Tumors and\rTumor-Like Lesions 761
Selected References 769
Chapter\r25. Sellar Neoplasms and Tumor-Like Lesions 771
Sellar Region Anatomy 772
Normal Imaging Variants 777
Congenital Lesions 784
Neoplasms 790
Miscellaneous Lesions 806
Differential Diagnosis of a\rSellar Region Mass 815
Selected References 818
Chapter\r26. Miscellaneous Tumors and Tumor- Like Conditions 819
Extracranial Tumors and Tumor-\rLike Conditions 819
Intracranial Pseudotumors 830
Selected References 834
Chapter\r27. Metastases and Paraneoplastic Syndromes 835
Metastatic Lesions 835
Paraneoplastic Syndromes 860
Selected References 866
Chapter\r28. Nonneoplastic Cysts 867
Scalp Cysts 868
Extraaxial Cysts 871
Parenchymal Cysts 887
Intraventricular Cysts 893
Selected References 901
Section 5:\rToxic, Metabolic, Degenerative, and CSF Disorders 904
Chapter 29.\rApproach to Toxic, Metabolic, Degenerative, and CSF Disorders 905
Anatomy and Physiology of the\rBasal Ganglia and Thalami 906
Toxic and Metabolic\rDisorders 908
Degenerative and CSF\rDisorders 917
Selected References 918
Chapter\r30. Toxic Encephalopathy 919
Alcohol and Related Disorders 919
Amphetamines and\rDerivatives 931
Opioids and Derivatives 935
Inhaled Gases and Toxins 936
Metal Poisoning and\rToxicity 942
Treatment-Related\rDisorders 943
Selected References 948
Chapter\r31. Inherited Metabolic Disorders 949
Normal Myelination and\rWhite Matter\rDevelopment 951
Classification of Inherited\rMetabolic Disorders 955
IMDs Predominantly\rAffecting White Matter 959
IMDs Predominantly\rAffecting Gray Matter 981
Disorders Affecting Both\rGray and White Matter 992
Selected References 1016
Chapter\r32. Acquired Metabolic and Systemic Disorders 1017
Hypertensive Encephalopathies 1017
Glucose Disorders 1029
Thyroid Disorders 1036
Parathyroid and Related\rDisorders 1040
Seizures and Related\rDisorders 1047
Miscellaneous Disorders 1056
Selected References 1069
Chapter\r33. Dementias and Brain Degenerations 1071
The Normal Aging Brain 1072
Dementias 1075
Degenerative Disorders 1096
Selected References 1117
Chapter\r34. Hydrocephalus and CSF Disorders 1119
Normal Development of the\rVentricles and Cisterns 1119
Normal Anatomy of the Ventricles and Cisterns 1120
Normal Variants 1124
Hydrocephalus 1129
CSF Leaks and Sequelae 1148
Selected References 1155
Section 6:\rCongenital Malformations of the Skull and Brain 1158
Chapter 35. Embryology and Approach to\rCongenital Malformations 1159
Cerebral Hemisphere Formation 1159
Midbrain and Hindbrain\rDevelopment 1163
Imaging Approach to Brain\rMalformations 1166
Chapter 36.\rPosterior Fossa Malformations 1169
Posterior Fossa Anatomy 1169
Chiari Malformations 1174
Hindbrain Malformations 1186
Selected References 1194
Chapter 37.\rCommissural and Cortical Maldevelopment 1195
Normal Development and\rAnatomy of the Cerebral\rCommissures 1195
Commissural Anomalies 1197
Malformations of Cortical\rDevelopment Overview 1201
Malformations With Abnormal\rCell Numbers/Types 1202
Abnormalities of Neuronal\rMigration 1210
Malformations Secondary to\rAbnormal Postmigrational\rDevelopment 1219
Selected References 1224
Chapter\r38. Holoprosencephalies, Related Disorders, and Mimics 1225
Anencephaly 1225
Holoprosencephaly 1225
Holoprosencephaly Variants 1231
Related Midline Disorders 1234
Holoprosencephaly Mimics 1237
Selected References 1240
Chapter 39.\rFamilial Cancer Predisposition Syndromes 1241
Neurofibromatosis and\rSchwannomatosis 1241
Other Common Familial\rTumor Syndromes 1254
Rare Familial Cancer\rSyndromes 1266
Selected References 1278
Chapter\r40. Vascular Neurocutaneous Syndromes 1279
Capillary Malformation\rSyndromes 1279
Other Vascular\rPhakomatoses 1285
Selected References 1294
Chapter 41.\rAnomalies of the Skull and Meninges 1295
Normal Development and\rAnatomy of the Skull Base 1295
Cephaloceles 1298
Craniosynostoses 1305
Meningeal Anomalies 1311
Selected References 1315
Index 1317