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Mosby's Manual of Diagnostic and Laboratory Tests - E-Book

Mosby's Manual of Diagnostic and Laboratory Tests - E-Book

Kathleen Deska Pagana | Timothy J. Pagana

(2017)

Additional Information

Book Details

Abstract

Writing care plans, understanding and performing tests, and interpreting test results is made easier with Mosby’s Manual of Diagnostic and Laboratory Tests, 6th Edition. This essential resource provides clear, concise overage of over 700 of the most commonly performed diagnostic and laboratory tests. Valuable in academic and clinical settings alike, it is beloved for its full-color design, user-friendly organization, and illustrations that help clarify keep concepts. Updated and streamlined content with new tests ensures you have the most relevant information. A new Diagnostic Testing for the Most Common Diseases section highlights the integration of medical testing as it relates to the top diseases or clinical syndromes.

  • Tests are presented comprehensively and consistently, in a sequence that best simulates priorities in clinical practice.
  • UNIQUE! Clinical Priorities boxes emphasize priorities and procedure considerations specific to understanding and performing tests.
  • UNIQUE! Test Results and Clinical Significance sections describe the significance of the test findings and discuss the pathophysiology of the disease process and how it relates to the test result.
  • UNIQUE! Home Care Responsibilities boxes focus on post-test factors for consideration.
  • UNIQUE! Related Tests sections list additional tests related to the main test — including tests that provide similar information, confirmatory information, and other tests used to evaluate the same organ, disease process, or symptom complex.
  • UNIQUE! Critical Values sections indicate test values of particular significance.
  • UNIQUE! Icons indicate drugs that increase or decrease test values and patient teaching priorities.
  • Age-Related Concerns boxes address pediatric and geriatric priorities.
  • NEW and UPDATED! New tests have been added and outdated tests have been removed to reflect current best practices.
  • NEW! A Diagnostic Testing for the Most Common Diseases section highlights the integration of medical testing as it relates to the top diseases or clinical syndromes.

Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC ES1
MOSBY’S Manual of Diagnostic and Laboratory Tests i
MOSBY’S: Manual of Diagnostic and Laboratory Tests iii
Copyright iv
Dedication v
Reviewers vi
Preface vii
Contents x
Diagnostic Testing for the Most Common Diseases xi
ADDISON’S DISEASE xi
ADRENAL FUNCTIONAL ABNORMALITIES xi
AIDS/IMMUNOLOGIC DEFICIENCY xi
ALLERGY xii
ALZHEIMER’S DISEASE/DEMENTIA xii
ANEMIA xii
ARTHRITIS xii
BACK PAIN xii
BENIGN PROSTATIC HYPERTROPHY xii
BLADDER CANCER xii
BOWEL OBSTRUCTION xiii
BREAST CANCER xiii
CARCINOID xiii
CARDIAC ARRHYTHMIA xiii
CELIAC DISEASE xiii
CERVICAL CANCER xiii
CIRRHOSIS xiii
COAGULATION ABNORMALITIES xiv
COLORECTAL CANCER xiv
COMA xiv
CONGESTIVE HEART FAILURE xiv
CORONARY OCCLUSIVE DISEASE xv
DIABETES xv
DIARRHEA xv
DYSFUNCTIONAL UTERINE BLEEDING xv
GALLBLADDER/BILIARY DISEASE xvi
GASTRO-ESOPHAGEAL REFLUX xvi
GASTROINTESTINAL BLEEDING xvi
HEMATURIA xvi
HEMOLYSIS xvi
HYPERTENSION xvi
INFERTILITY xvii
INFLAMMATORY BOWEL DISEASE xvii
IRON DEFICIENCY ANEMIA xvii
JAUNDICE xvii
LEUKEMIA/LYMPHOMA xvii
LIVER DISEASES/FAILURE xvii
LUNG CANCER xviii
LUPUS ERYTHEMATOSUS xviii
MATERNAL/FETAL EVALUATION xviii
MENOPAUSE xix
OSTEOPOROSIS xix
OVARIAN CANCER xix
PANCREATITIS xix
PARATHYROID FUNCTIONAL ABNORMALITIES xix
PEPTIC ULCER xix
PHEOCHROMOCYTOMA xix
PITUITARY FUNCTIONAL ABNORMALITIES xx
PNEUMONIA xx
PROSTATE CANCER xx
PULMONARY DISEASE ACUTE/CHRONIC xx
RENAL DISEASE xx
RENAL FAILURE xxi
RHEUMATOID ARTHRITIS xxi
SARCOIDOSIS xxi
SEXUAL ASSAULT xxi
SEXUALLY TRANSMITTED DISEASES xxi
SHORTNESS OF BREATH xxi
SLEEP APNEA xxi
STREPTOCOCCUS INFECTION xxi
STROKE SYNDROME xxii
THROMBOCYTOPENIA xxii
THROMBOSIS xxii
THYROID CANCER xxii
THYROID FUNCTIONAL ABNORMALITIES xxii
TRANSFUSION REACTION xxii
TUBERCULOSIS xxiii
URINARY STONES xxiii
VASCULAR DISEASE xxiii
1 - Guidelines for Proper Test Preparation and Performance 1
Overview 1
CODING FOR DIAGNOSTIC AND LABORATORY TESTS 1
LABORATORY METHODS 2
Latex Agglutination 2
Agglutination Inhibition 2
Hemagglutination 2
Electrophoresis 2
Immunoelectrophoresis 3
Immunofixation Electrophoresis 3
Immunoassay 3
Enzyme-Linked Immunosorbent Assay 3
Autoimmune Enzyme Immunoassay 3
Chemiluminescent Immunoassays 3
Fluorescent Immunoassays 4
Polymerase Chain Reaction 4
Fluorescence In Situ Hybridization 5
STANDARD PRECAUTIONS 5
PROPER SEQUENCING AND SCHEDULING OF TESTS 6
PROCEDURE AND PATIENT CARE 6
Before the Test 6
Patient Identification 7
Patient Education 7
Variables Affecting Test Results 7
During Testing 8
Specimen Collection 8
Transport and Processing of the Specimen 8
A Note About SI Units 8
After the Test 8
Reporting Test Results 8
2 - Blood Studies 10
Overview 13
Reasons for Obtaining Blood Studies 13
Methods of Blood Collection 13
Venous Puncture 13
Background Information 13
Collection Tubes 14
Technique 14
Before 14
During 16
After 16
Potential Complications 17
Preventing Interfering Factors 17
Drawing Blood From an Indwelling Venous Catheter 17
Drawing a Panel of Blood Studies 17
Arterial Puncture 17
Background Information 17
Technique 18
Before 18
During 18
After 18
3 - Electrodiagnostic Tests 477
Overview 477
REASONS FOR PERFORMING ELECTRODIAGNOSTIC STUDIES 477
PROCEDURAL CARE FOR ELECTRODIAGNOSTIC STUDIES 477
Before 477
During 478
After 478
POTENTIAL COMPLICATIONS OF ELECTRODIAGNOSTIC STUDIES 478
Cardiac Stress Testing 478
Contraction Stress Test 479
REPORTING OF RESULTS 479
Caloric Study (Oculovestibular Reflex Study) 479
NORMAL FINDINGS 479
INDICATIONS 479
TEST EXPLANATION 479
CONTRAINDICATIONS 479
INTERFERING FACTORS 479
PROCEDURE AND PATIENT CARE 480
Before 480
During 480
After 480
TEST RESULTS AND CLINICAL SIGNIFICANCE 480
RELATED TEST 480
NORMAL FINDINGS 481
INDICATIONS 481
TEST EXPLANATION 481
CONTRAINDICATIONS 483
POTENTIAL COMPLICATIONS 483
INTERFERING FACTORS 484
PROCEDURE AND PATIENT CARE 484
Before 484
During 484
After 484
TEST RESULTS AND CLINICAL SIGNIFICANCE 484
RELATED TESTS 485
Electrocardio 485
NORMAL FINDINGS 485
INDICATIONS 485
TEST EXPLANATION 485
INTERFERING FACTORS 488
PROCEDURE AND PATIENT CARE 488
Before 488
During 488
After 489
TEST RESULTS AND CLINICAL SIGNIFICANCE 489
RELATED TESTS 490
Electroencephalography (Electroencephalogram [EEG]) 490
NORMAL FINDINGS 490
INDICATIONS 490
TEST EXPLANATION 490
INTERFERING FACTORS 491
PROCEDURE AND PATIENT CARE 491
Before 491
During 492
After 492
TEST RESULTS AND CLINICAL SIGNIFICANCE 492
RELATED TEST 494
Electromyography (EMG) 494
NORMAL FINDINGS 494
INDICATIONS 494
TEST EXPLANATION 495
CONTRAINDICATIONS 495
POTENTIAL COMPLICATIONS 495
INTERFERING FACTORS 495
PROCEDURE AND PATIENT CARE 495
Before 495
During 496
After 497
TEST RESULTS AND CLINICAL SIGNIFICANCE 497
RELATED TEST 497
Electronystagmography (ENG, Electrooculography) 497
NORMAL FINDINGS 497
INDICATIONS 498
TEST EXPLANATION 498
CONTRAINDICATIONS 498
INTERFERING FACTORS 498
PROCEDURE AND PATIENT CARE 498
Before 498
During 499
After 499
TEST RESULTS AND CLINICAL SIGNIFICANCE 499
RELATED TEST 500
Electrophysiologic Study (EPS, Cardiac Mapping) 500
NORMAL FINDINGS 500
INDICATIONS 500
TEST EXPLANATION 500
CONTRAINDICATIONS 500
POTENTIAL COMPLICATIONS 500
INTERFERING FACTORS 501
PROCEDURE AND PATIENT CARE 501
Before 501
During 501
After 502
TEST RESULTS AND CLINICAL SIGNIFICANCE 502
RELATED TEST 502
Evoked Potential Studies (EP Studies, Evoked Brain Potentials, Evoked Responses, Visual-Evoked Responses [VERs], Auditory Brains... 502
NORMAL FINDINGS 502
INDICATIONS 502
TEST EXPLANATION 503
PROCEDURE AND PATIENT CARE 505
Before 505
During 505
After 505
TEST RESULTS AND CLINICAL SIGNIFICANCE 505
Prolonged Latency for VERs 505
Prolonged Latency for ABEPs 506
Abnormal Latency for SERs 506
RELATED TEST 506
Fetal Contraction Stress Test (CST, Oxytocin Challenge Test [OCT]) 507
NORMAL FINDINGS 507
INDICATIONS 507
TEST EXPLANATION 507
CONTRAINDICATIONS 508
POTENTIAL COMPLICATIONS 508
INTERFERING FACTORS 508
PROCEDURE AND PATIENT CARE 508
Before 508
During 509
After 509
TEST RESULTS AND CLINICAL SIGNIFICANCE 509
RELATED TEST 509
Fetal Nonstress Test (NST, Fetal Activity Determination) 509
NORMAL FINDINGS 509
INDICATIONS 509
TEST EXPLANATION 510
PROCEDURE AND PATIENT CARE 510
Before 510
During 510
After 511
TEST RESULTS AND CLINICAL SIGNIFICANCE 511
RELATED TEST 511
Holter Monitoring (Ambulatory Monitoring, Ambulatory Electrocardiography, Event Recorder) 511
NORMAL FINDINGS 511
INDICATIONS 511
TEST EXPLANATION 511
CONTRAINDICATIONS 512
INTERFERING FACTORS 512
PROCEDURE AND PATIENT CARE 512
Before 512
During 513
After 513
TEST RESULTS AND CLINICAL SIGNIFICANCE 513
RELATED TEST 514
Nerve Conduction Studies (NCS, Electroneurography) 514
NORMAL FINDINGS 514
INDICATIONS 514
TEST EXPLANATION 514
INTERFERING FACTORS 515
PROCEDURE AND PATIENT CARE 515
Before 515
During 515
After 515
TEST RESULTS AND CLINICAL SIGNIFICANCE 515
RELATED TEST 516
Pelvic Floor Sphincter Electromyography (Pelvic Floor Sphincter EMG, Rectal EMG Procedure) 516
NORMAL FINDINGS 516
INDICATIONS 516
TEST EXPLANATION 516
CONTRAINDICATIONS 516
PROCEDURE AND PATIENT CARE 517
Before 517
During 517
After 517
TEST RESULTS AND CLINICAL SIGNIFICANCE 517
RELATED TESTS 517
4 - Endoscopic Studies 518
Overview 518
INDICATIONS FOR ENDOSCOPY 518
INSTRUMENTATION 520
PROCEDURAL CARE FOR THE ENDOSCOPY PATIENT 520
Pulmonary and Gastrointestinal Endoscopy 520
Before 520
During 521
5 - Fluid Analysis Studies 567
Overview 567
REASONS FOR PERFORMING FLUID ANALYSIS 567
PROCEDURAL CARE FOR FLUID ANALYSIS 568
Before 568
During 568
After 569
POTENTIAL COMPLICATIONS OF FLUID ANALYSIS TESTING 569
REPORTING RESULTS 569
Amniocentesis (Amniotic Fluid Analysis) 569
NORMAL FINDINGS 569
INDICATIONS 570
TEST EXPLANATION 570
CONTRAINDICATIONS 572
POTENTIAL COMPLICATIONS 572
INTERFERING FACTORS 573
PROCEDURE AND PATIENT CARE 573
Before 573
During 573
After 574
TEST RESULTS AND CLINICAL SIGNIFICANCE 575
RELATED TESTS 575
NORMAL FINDINGS 576
INDICATIONS 576
TEST EXPLANATION 576
PROCEDURE AND PATIENT CARE 576
Before 576
During 576
After 576
TEST RESULTS AND CLINICAL SIGNIFICANCE 577
?Decreased Levels 577
RELATED TESTS 577
Arthrocentesis With Synovial Fluid Analysis (Synovial Fluid Analysis, Joint Aspiration) 577
NORMAL FINDINGS 577
TEST EXPLANATION 577
CONTRAINDICATIONS 578
POTENTIAL COMPLICATIONS 579
PROCEDURE AND PATIENT CARE 579
Before 579
During 579
After 579
TEST RESULTS AND CLINICAL SIGNIFICANCE 579
RELATED TEST 580
Breast Cyst and Nipple Discharge Fluid Analysis 580
NORMAL FINDINGS 580
INDICATIONS 580
TEST EXPLANATION 580
POTENTIAL COMPLICATIONS 581
PROCEDURE AND PATIENT CARE 581
Before 581
During 581
Nipple Discharge 581
Cyst Aspiration 581
After 582
TEST RESULTS AND CLINICAL SIGNIFICANCE 582
RELATED TESTS 582
Breast Ductal Lavage 582
NORMAL FINDINGS 582
POSSIBLE CRITICAL VALUES 582
INDICATIONS 582
TEST EXPLANATION 582
CONTRAINDICATIONS 583
POTENTIAL COMPLICATIONS 583
PROCEDURE AND PATIENT CARE 583
Before 583
During 583
After 583
TEST RESULTS AND CLINICAL SIGNIFICANCE 583
RELATED TESTS 584
Fetal Fibronectin (fFN) 584
NORMAL FINDINGS 584
INDICATIONS 584
TEST EXPLANATION 584
PROCEDURE AND PATIENT CARE 584
Before 584
During 584
After 585
TEST RESULTS AND CLINICAL SIGNIFICANCE 585
?Increased Levels 585
Human Papillomavirus (HPV Test, HPV DNA Testing) 585
NORMAL FINDINGS 585
INDICATIONS 585
TEST EXPLANATION 585
INTERFERING FACTORS 587
PROCEDURE AND PATIENT CARE 587
Before 587
During 587
After 588
TEST RESULTS AND CLINICAL SIGNIFICANCE 588
RELATED TEST 588
NORMAL FINDINGS 588
INDICATIONS 589
TEST EXPLANATION 589
Pressure 590
Color 590
Blood 590
Cells 591
Culture and Sensitivity 591
Protein 592
Glucose 592
Chloride 592
Lactic Dehydrogenase 592
Lactic Acid 592
Cytology 593
Tumor Markers 593
Serology for Syphilis 593
Glutamine 593
C-Reactive Protein 593
CONTRAINDICATIONS 593
POTENTIAL COMPLICATIONS 594
PROCEDURE AND PATIENT CARE 594
Before 594
During 594
After 595
TEST RESULTS AND CLINICAL SIGNIFICANCE 596
RELATED TESTS 596
Pancreatic Enzymes (Pancreatic Secretory Test, Amylase, Lipase, Trypsin, Chymotrypsin) 596
NORMAL FINDINGS 596
INDICATIONS 596
TEST EXPLANATION 597
PROCEDURE AND PATIENT CARE 597
Before 597
During 597
After 598
TEST RESULTS AND CLINICAL SIGNIFICANCE 598
?Increased Levels 598
?Decreased Levels 598
RELATED TESTS 598
Paracentesis (Peritoneal Fluid Analysis, Abdominal Paracentesis, Ascitic Fluid Cytology, Peritoneal Tap/Lavage) 598
NORMAL FINDINGS 598
INDICATIONS 599
TEST EXPLANATION 599
CONTRAINDICATIONS 600
POTENTIAL COMPLICATIONS 600
PROCEDURE AND PATIENT CARE 600
Before 600
During 601
After 601
TEST RESULTS AND CLINICAL SIGNIFICANCE 601
Exudate 601
Transudate 602
RELATED TESTS 602
Pericardiocentesis 602
NORMAL FINDINGS 602
INDICATIONS 602
TEST EXPLANATION 602
CONTRAINDICATIONS 603
POTENTIAL COMPLICATIONS 603
PROCEDURE AND PATIENT CARE 603
Before 603
During 603
After 604
TEST RESULTS AND CLINICAL SIGNIFICANCE 605
RELATED TESTS 605
Semen Analysis (Sperm Count, Sperm Examination, Seminal Cytology, Semen Examination) 606
NORMAL FINDINGS 606
INDICATIONS 606
TEST EXPLANATION 606
INTERFERING FACTORS 607
PROCEDURE AND PATIENT CARE 608
Before 608
During 608
After 608
TEST RESULTS AND CLINICAL SIGNIFICANCE 608
RELATED TESTS 609
Sexual Assault Testing 609
NORMAL FINDINGS 609
INDICATIONS 609
TEST EXPLANATION 609
CONTRAINDICATIONS 611
INTERFERING FACTORS 611
PROCEDURE AND PATIENT CARE 611
Before 611
During 611
After 611
TEST RESULTS AND CLINICAL SIGNIFICANCE 612
Sims-Huhner (Postcoital, Postcoital Cervical Mucus, Cervical Mucus Sperm Penetration) 612
NORMAL FINDINGS 612
INDICATIONS 612
TEST EXPLANATION 612
PROCEDURE AND PATIENT CARE 613
Before 613
During 613
After 613
TEST RESULTS AND CLINICAL SIGNIFICANCE 613
RELATED TESTS 613
Sweat Electrolytes (Iontophoretic Sweat) 613
NORMAL FINDINGS 613
INDICATIONS 614
TEST EXPLANATION 614
INTERFERING FACTORS 614
PROCEDURE AND PATIENT CARE 615
Before 615
During 615
After 615
TEST RESULTS AND CLINICAL SIGNIFICANCE 616
RELATED TESTS 616
Thoracentesis and Pleural Fluid Analysis (Pleural Tap) 616
NORMAL FINDINGS 616
INDICATIONS 616
TEST EXPLANATION 616
Gross Appearance 617
Cell Counts 617
Protein Content 618
Lactic Dehydrogenase 618
Glucose 618
Amylase 618
Triglyceride 618
Gram Stain and Bacteriologic Culture 618
Cultures for Mycobacterium tuberculosis and Fungus 618
Cytology 619
Carcinoembryonic Antigen 619
Special Tests 619
CONTRAINDICATIONS 619
POTENTIAL COMPLICATIONS 619
PROCEDURE AND PATIENT CARE 620
Before 620
During 620
After 620
TEST RESULTS AND CLINICAL SIGNIFICANCE 621
Exudate 621
Transudate 621
RELATED TESTS 622
6 - Manometric Studies 623
Overview 623
PROCEDURAL CARE FOR MANOMETRIC STUDIES 623
Before 623
During 623
After 624
POTENTIAL COMPLICATIONS OF MANOMETRIC STUDIES 624
REPORTING OF RESULTS 624
Esophageal Function Studies (Esophageal Manometry, Esophageal Motility Studies) 624
NORMAL FINDINGS 624
INDICATIONS 624
TEST EXPLANATION 625
Manometric Studies 625
Acid Reflux With pH Probe 625
Acid Clearing 626
Bernstein Test (Acid Perfusion) 626
The Bernstein test is simply an attempt to reproduce the symptoms of gastroesophageal reflux. If the patient suffers pain with t... 626
CONTRAINDICATIONS 626
POTENTIAL COMPLICATIONS 626
INTERFERING FACTORS 626
PROCEDURE AND PATIENT CARE 626
Before 626
During 626
After 627
TEST RESULTS AND CLINICAL SIGNIFICANCE 627
RELATED TESTS 628
Plethysmography, Arterial 628
NORMAL FINDINGS 628
INDICATIONS 628
TEST EXPLANATION 628
INTERFERING FACTORS 629
PROCEDURE AND PATIENT CARE 629
Before 629
During 629
After 629
TEST RESULTS AND CLINICAL SIGNIFICANCE 630
RELATED TESTS 630
Tilt-Table Testing 630
NORMAL FINDINGS 630
INDICATIONS 630
TEST EXPLANATION 630
INTERFERING FACTORS 630
PROCEDURE AND PATIENT CARE 631
Before 631
During 631
After 631
TEST RESULTS AND CLINICAL SIGNIFICANCE 631
RELATED TEST 631
Tourniquet Test (Capillary Fragility) 631
NORMAL FINDINGS 631
INDICATIONS 631
TEST EXPLANATION 632
INTERFERING FACTORS 632
PROCEDURE AND PATIENT CARE 632
Before 632
During 632
Positive Pressure Test 632
Negative Pressure Test 632
After 632
TEST RESULTS AND CLINICAL SIGNIFICANCE 632
Positive: >2 Petechiae 632
RELATED TESTS 633
NORMAL FINDINGS 633
Maximal Urethral Pressures in Normal Patients (cm H2O) 633
INDICATIONS 633
TEST EXPLANATION 634
CONTRAINDICATIONS 634
PROCEDURE AND PATIENT CARE 635
Before 635
During 635
After 636
TEST RESULTS AND CLINICAL SIGNIFICANCE 636
RELATED TESTS 637
7 - Microscopic Studies and Associated Testing 638
OVERVIEW 638
REASONS FOR PERFORMING MICROSCOPIC STUDIES 638
PROCEDURAL CARE FOR MICROSCOPIC STUDIES 639
Before 639
During 640
After 640
LABORATORY HANDLING OF SPECIMENS 640
REPORTING OF RESULTS 640
Acid-Fast Bacilli Smear (AFB Smear) 641
NORMAL FINDINGS 641
INDICATIONS 641
TEST EXPLANATION 641
INTERFERING FACTORS 641
PROCEDURE AND PATIENT CARE 642
Before 642
During 642
After 642
TEST RESULTS AND CLINICAL SIGNIFICANCE 642
RELATED TESTS 642
Blood Culture and Sensitivity (Blood C&S) 642
NORMAL FINDINGS 642
INDICATIONS 642
TEST EXPLANATION 643
INTERFERING FACTORS 644
PROCEDURE AND PATIENT CARE 644
Before 644
During 644
After 644
TEST RESULTS AND CLINICAL SIGNIFICANCE 644
Blood Smear (Peripheral Blood Smear, Red Blood Cell Morphology, RBC Smear, WBC Differential) 644
NORMAL FINDINGS 644
INDICATIONS 644
TEST EXPLANATION 645
RBC Size Abnormalities 645
RBC Shape Abnormalities 645
RBC Color Abnormalities 645
RBC Intracellular Structure 646
WBC Examination 646
Platelet Examination 646
PROCEDURE AND PATIENT CARE 646
TEST RESULTS AND CLINICAL SIGNIFICANCE 646
RELATED TESTS 646
Bone Marrow Biopsy (Bone Marrow Examination, Bone Marrow Aspiration) 647
NORMAL FINDINGS 647
?Critical Values 647
INDICATIONS 647
TEST EXPLANATION 648
CONTRAINDICATIONS 649
POTENTIAL COMPLICATIONS 649
PROCEDURE AND PATIENT CARE 650
Before 650
During 650
After 650
TEST RESULTS AND CLINICAL SIGNIFICANCE 651
RELATED TEST 652
DNA Ploidy 652
S-Phase Fraction 652
HER 2 Protein 652
Cathepsin D 652
p53 Protein 652
Ki67 Protein 652
INDICATIONS 652
TEST EXPLANATION 652
Ploidy (DNA Index) and S-Phase Fraction 653
Cathepsin D 653
HER-2 (c erbB2, neu) Protein 653
p53 Protein 654
Ki67 Protein 654
INTERFERING FACTORS 654
PROCEDURE AND PATIENT CARE 654
Before 654
During 654
After 654
TEST RESULTS AND CLINICAL SIGNIFICANCE 654
RELATED TESTS 654
Cervical Biopsy (Punch Biopsy, Endocervical Biopsy, LEEP Cervical Biopsy, Cone Biopsy, Conization) 655
NORMAL FINDINGS 655
?Critical Values 655
INDICATIONS 655
TEST EXPLANATION 655
CONTRAINDICATIONS 655
POTENTIAL COMPLICATIONS 655
PROCEDURE AND PATIENT CARE 656
Before 656
During 656
After 656
TEST RESULTS AND CLINICAL SIGNIFICANCE 656
RELATED TESTS 657
Chlamydia 657
NORMAL FINDINGS 657
INDICATIONS 657
TEST EXPLANATION 657
INTERFERING FACTORS 658
PROCEDURE AND PATIENT CARE 658
Before 658
During 658
After 659
TEST RESULTS AND CLINICAL SIGNIFICANCE 659
RELATED TEST 659
Endometrial Biopsy 659
NORMAL FINDINGS 659
INDICATIONS 659
TEST EXPLANATION 659
CONTRAINDICATIONS 660
POTENTIAL COMPLICATIONS 660
PROCEDURE AND PATIENT CARE 660
Before 660
During 660
After 660
TEST RESULTS AND CLINICAL SIGNIFICANCE 661
Estrogen Receptor Assay (ER Assay, ERA, Estradiol Receptor) 661
Immunohistochemistry 661
Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) 661
INDICATIONS 661
TEST EXPLANATION 662
INTERFERING FACTORS 662
PROCEDURE AND PATIENT CARE 662
Before 662
During 662
After 662
TEST RESULTS AND CLINICAL SIGNIFICANCE 662
RELATED TESTS 662
NORMAL FINDINGS 663
INDICATIONS 663
TEST EXPLANATION 663
INTERFERING FACTORS 664
PROCEDURE AND PATIENT CARE 664
TEST RESULTS AND CLINICAL SIGNIFICANCE 664
?Increased Levels 664
RELATED TESTS 664
Herpes Simplex (Herpesvirus Types 1 and 2, Herpes Simplex Virus Type 1 and 2 [HSV 1 and 2], Herpes Genitalis) 665
NORMAL FINDINGS 665
INDICATIONS 665
TEST EXPLANATION 665
PROCEDURE AND PATIENT CARE 666
Before 666
During 666
Urethral Culture 666
Cervical Culture 666
Blood for Serologic Study 667
Molecular PCR Tissue and Other Fluids 667
After 667
TEST RESULTS AND CLINICAL SIGNIFICANCE 667
RELATED TEST 667
Liver Biopsy 667
NORMAL FINDINGS 667
INDICATIONS 667
TEST EXPLANATION 667
CONTRAINDICATIONS 668
POTENTIAL COMPLICATIONS 669
PROCEDURE AND PATIENT CARE 669
Before 669
During 669
After 670
TEST RESULTS AND CLINICAL SIGNIFICANCE 670
RELATED TESTS 670
Lung Biopsy 670
NORMAL FINDINGS 670
INDICATIONS 671
TEST EXPLANATION 671
CONTRAINDICATIONS 671
POTENTIAL COMPLICATIONS 671
PROCEDURE AND PATIENT CARE 672
Before 672
During 672
Transbronchial Lung Biopsy 672
Transbronchial Needle Aspiration 672
Transcatheter Bronchial Brushing 673
Percutaneous Needle Biopsy 673
Open Lung Biopsy 673
Thoracoscopic Biopsy 673
After 673
TEST RESULTS AND CLINICAL SIGNIFICANCE 673
RELATED TESTS 674
NORMAL FINDINGS 674
INDICATIONS 674
TEST EXPLANATION 674
PROCEDURE AND PATIENT CARE 675
Before 675
During 675
After 675
TEST RESULTS AND CLINICAL SIGNIFICANCE 675
RELATED TESTS 675
Pancreatobiliary FISH Testing 675
NORMAL FINDINGS 675
INDICATIONS 675
TEST EXPLANATION 675
CONTRAINDICATIONS 676
POTENTIAL COMPLICATIONS 676
INTERFERING FACTORS 676
PROCEDURE AND PATIENT CARE 676
Before 676
During 676
After 676
TEST RESULTS AND CLINICAL SIGNIFICANCE 676
RELATED TEST 677
Papanicolaou Test (Pap Test, Pap Smear, Cytologic Test for Cancer, Liquid-Based Cervical Cytology [LBCC], ThinPrep) 677
NORMAL FINDINGS 677
INDICATIONS 677
TEST EXPLANATION 677
CONTRAINDICATIONS 679
INTERFERING FACTORS 679
PROCEDURE AND PATIENT CARE 680
Before 680
During 680
After 681
TEST RESULTS AND CLINICAL SIGNIFICANCE 681
RELATED TESTS 681
Parkinson Disease Testing 681
NORMAL FINDINGS 681
INDICATIONS 682
TEST EXPLANATION 682
POTENTIAL COMPLICATIONS 682
PROCEDURE AND PATIENT CARE 682
Before 682
During 682
After 682
TEST RESULTS AND CLINICAL SIGNIFICANCE 683
RELATED TESTS 683
Pleural Biopsy 683
NORMAL FINDINGS 683
INDICATIONS 683
TEST EXPLANATION 683
CONTRAINDICATIONS 683
POTENTIAL COMPLICATIONS 683
PROCEDURE AND PATIENT CARE 684
Before 684
During 684
After 684
TEST RESULTS AND CLINICAL SIGNIFICANCE 684
RELATED TESTS 685
Progesterone Receptor Assay (PR Assay, PRA, PgR) 685
Immunochemistry 685
Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) 685
INDICATIONS 685
TEST EXPLANATION 685
INTERFERING FACTORS 686
PROCEDURE AND PATIENT CARE 686
Before 686
During 686
After 686
TEST RESULTS AND CLINICAL SIGNIFICANCE 686
RELATED TESTS 686
Prostate Cancer Genomics (Prostate Cancer Molecular Testing, Oncotype DX Prostate Genotyping, Prolaris, ProMark, Decipher) 686
NORMAL FINDINGS 686
INDICATIONS 687
TEST EXPLANATION 687
CONTRAINDICATIONS 687
PROCEDURE AND PATIENT CARE 687
Before 687
During 688
After 688
TEST RESULTS AND CLINICAL SIGNIFICANCE 688
RELATED TESTS 688
Renal Biopsy (Kidney Biopsy) 688
NORMAL FINDINGS 688
INDICATIONS 688
TEST EXPLANATION 688
CONTRAINDICATIONS 689
POTENTIAL COMPLICATIONS 689
PROCEDURE AND PATIENT CARE 690
Before 690
During 690
After 690
TEST RESULTS AND CLINICAL SIGNIFICANCE 691
SARS Viral Testing 691
NORMAL FINDINGS 691
INDICATIONS 691
TEST EXPLANATION 691
PROCEDURE AND PATIENT CARE 692
Before 692
During 692
After 692
TEST RESULTS AND CLINICAL SIGNIFICANCE 693
Sexually Transmitted Disease Testing (STD Culture, Culture of Cervix, Urethra, and Anus) 693
NORMAL FINDINGS 693
INDICATION 693
TEST EXPLANATION 693
INTERFERING FACTORS 694
PROCEDURE AND PATIENT CARE 695
Before 695
During 695
Cervical Culture 695
Anal Canal Culture 695
Oropharyngeal Culture 695
Urethral Culture 695
Urine Culture 696
After 696
TEST RESULTS AND CLINICAL SIGNIFICANCE 696
RELATED TESTS 696
NORMAL FINDINGS 697
INDICATIONS 697
TEST EXPLANATION 697
PROCEDURE AND PATIENT CARE 697
Before 697
During 697
After 697
TEST RESULTS AND CLINICAL SIGNIFICANCE 698
RELATED TESTS 698
Sputum Culture and Sensitivity (Sputum C&S, Sputum Culture, and Gram Stain) 698
NORMAL FINDINGS 698
INDICATIONS 698
TEST EXPLANATION 698
PROCEDURE AND PATIENT CARE 699
Before 699
During 699
After 699
TEST RESULTS AND CLINICAL SIGNIFICANCE 700
RELATED TEST 700
Sputum Cytology 700
NORMAL FINDINGS 700
INDICATIONS 700
TEST EXPLANATION 700
INTERFERING FACTORS 700
PROCEDURE AND PATIENT CARE 701
Before 701
During 701
After 701
TEST RESULTS AND CLINICAL SIGNIFICANCE 701
RELATED TEST 701
Throat and Nose Cultures 702
NORMAL FINDINGS 702
INDICATIONS 702
TEST EXPLANATION 702
INTERFERING FACTORS 703
PROCEDURE AND PATIENT CARE 703
Before 703
During 704
After 704
TEST RESULTS AND CLINICAL SIGNIFICANCE 704
RELATED TEST 705
NORMAL FINDINGS 705
INDICATIONS 705
TEST EXPLANATION 705
PROCEDURE AND PATIENT CARE 706
Before 706
During 706
After 706
TEST RESULTS AND CLINICAL SIGNIFICANCE 706
RELATED TESTS 706
Thyroid Fine Needle Aspiration Biopsy (FNAB, Skinny-Needle Thyroid Biopsy, Fine Needle Aspiration [FNA]) 706
NORMAL FINDINGS 706
INDICATIONS 706
TEST EXPLANATION 707
CONTRAINDICATIONS 707
POTENTIAL COMPLICATIONS 707
PROCEDURE AND PATIENT CARE 707
Before 707
During 707
After 708
TEST RESULTS AND CLINICAL SIGNIFICANCE 708
RELATED TESTS 708
Tuberculosis Culture (TB Culture, BACTEC Method, Polymerase Chain Reaction, AFB Smear) 708
NORMAL FINDINGS 708
INDICATIONS 708
TEST EXPLANATION 708
INTERFERING FACTORS 709
PROCEDURE AND PATIENT CARE 709
Before 709
During 709
After 710
TEST RESULTS AND CLINICAL SIGNIFICANCE 710
RELATED TESTS 710
Tuberculosis Testing (TB Testing, Interferon Gamma Release Assay [IGRA, T-Spot.TB], QuantiFERON-TB Gold [QFT, QFT-G, TB Gold Tes... 710
TEST EXPLANATION 710
INTERFERING FACTORS 711
PROCEDURE AND PATIENT CARE 712
Before 712
During 712
After 712
TEST RESULTS AND CLINICAL SIGNIFICANCE 712
?Increased Levels 712
RELATED TESTS 712
Varicella Virus Testing (Antibody Testing for Varicella Zoster Virus, Varicella Zoster Virus [VZV], Herpes Virus-3) 712
NORMAL FINDINGS 712
INDICATIONS 713
TEST EXPLANATION 713
PROCEDURE AND PATIENT CARE 713
Before 713
During 714
After 714
TEST RESULTS AND CLINICAL SIGNIFICANCE 714
RELATED TESTS 714
Virus Testing 714
NORMAL FINDINGS 714
INDICATIONS 714
TEST EXPLANATION 714
INTERFERING FACTORS 716
PROCEDURE AND PATIENT CARE 717
Before 717
During 717
After 717
TEST RESULTS AND CLINICAL SIGNIFICANCE 717
RELATED TEST 717
Wound and Soft-Tissue Culture and Sensitivity (C&S) 717
NORMAL FINDINGS 717
INDICATIONS 717
TEST EXPLANATION 718
INTERFERING FACTORS 718
PROCEDURE AND PATIENT CARE 718
Before 718
During 718
After 719
TEST RESULTS AND CLINICAL SIGNIFICANCE 719
Zika Virus (ZIKV) 719
NORMAL FINDINGS 719
INDICATIONS 719
TEST EXPLANATION 720
INTERFERING FACTORS 720
PROCEDURE AND PATIENT CARE 720
TEST RESULTS AND CLINICAL SIGNIFICANCE 720
8 - Nuclear Scanning 721
Overview 721
REASONS FOR PERFORMING NUCLEAR MEDICINE STUDIES 721
PROCEDURAL CARE FOR NUCLEAR SCANS 723
Before 723
During 723
After 723
REPORTING OF RESULTS 724
Bone Scan 724
NORMAL FINDINGS 724
INDICATIONS 724
TEST EXPLANATION 724
CONTRAINDICATIONS 725
PROCEDURE AND PATIENT CARE 726
Before 726
During 726
After 727
TEST RESULTS AND CLINICAL SIGNIFICANCE 727
RELATED TESTS 727
Brain Scan (Cisternogram, Cerebral Blood Flow, DaT Scan) 727
NORMAL FINDINGS 727
INDICATIONS 728
TEST EXPLANATION 728
CONTRAINDICATIONS 729
INTERFERING FACTORS 729
PROCEDURE AND PATIENT CARE 729
Before 729
During 730
After 730
TEST RESULTS AND CLINICAL SIGNIFICANCE 731
RELATED TESTS 731
NORMAL FINDINGS 731
INDICATIONS 731
TEST EXPLANATION 732
CONTRAINDICATIONS 732
PROCEDURE AND PATIENT CARE 732
Before 732
During 732
After 733
TEST RESULTS AND CLINICAL SIGNIFICANCE 733
RELATED TESTS 733
Cardiac Nuclear Scan (Myocardial Perfusion Scan, Myocardial Perfusion Imaging, Myocardial Scan, Cardiac Scan, Heart Scan, Thalli... 733
NORMAL FINDINGS 733
INDICATIONS 733
TEST EXPLANATION 734
INTERFERING FACTORS 736
PROCEDURE AND PATIENT CARE 736
Before 736
During 737
After 738
TEST RESULTS AND CLINICAL SIGNIFICANCE 738
RELATED TESTS 738
NORMAL FINDINGS 738
INDICATIONS 738
TEST EXPLANATION 739
CONTRAINDICATIONS 739
INTERFERING FACTORS 739
PROCEDURE AND PATIENT CARE 740
Before 740
During 741
After 741
TEST RESULTS AND CLINICAL SIGNIFICANCE 741
RELATED TESTS 741
Gallium Scan 741
NORMAL FINDINGS 741
INDICATIONS 741
TEST EXPLANATION 742
CONTRAINDICATIONS 742
INTERFERING FACTORS 742
PROCEDURE AND PATIENT CARE 742
Before 742
During 743
After 743
TEST RESULTS AND CLINICAL SIGNIFICANCE 743
Gastric Emptying Scan 743
NORMAL FINDINGS 743
INDICATIONS 743
TEST EXPLANATION 743
CONTRAINDICATIONS 744
INTERFERING FACTORS 744
PROCEDURE AND PATIENT CARE 744
Before 744
During 745
After 745
TEST RESULTS AND CLINICAL SIGNIFICANCE 745
RELATED TEST 745
Gastroesophageal Reflux Scan (GE Reflux Scan, Aspiration Scan) 745
NORMAL FINDINGS 745
INDICATIONS 746
TEST EXPLANATION 746
CONTRAINDICATIONS 746
PROCEDURE AND PATIENT CARE 746
Before 746
During 746
GE Reflux Scan 746
Aspiration Scan 747
After 747
TEST RESULTS AND CLINICAL SIGNIFICANCE 747
RELATED TEST 747
Gastrointestinal Bleeding Scan (Abdominal Scintigraphy, GI Scintigraphy) 747
NORMAL FINDINGS 747
INDICATIONS 747
TEST EXPLANATION 747
CONTRAINDICATIONS 748
INTERFERING FACTORS 749
PROCEDURE AND PATIENT CARE 749
Before 749
During 749
After 749
TEST RESULTS AND CLINICAL SIGNIFICANCE 750
RELATED TESTS 750
Liver/Spleen Scanning (Liver Scanning) 750
NORMAL FINDINGS 750
INDICATIONS 750
TEST EXPLANATION 750
CONTRAINDICATIONS 751
INTERFERING FACTORS 751
PROCEDURE AND PATIENT CARE 751
Before 751
During 752
After 752
TEST RESULTS AND CLINICAL SIGNIFICANCE 752
RELATED TESTS 753
Lung Scan (Ventilation/Perfusion Scanning [VPS], V/Q Scan) 753
NORMAL FINDINGS 753
INDICATIONS 753
TEST EXPLANATION 753
CONTRAINDICATIONS 755
INTERFERING FACTORS 755
PROCEDURE AND PATIENT CARE 755
Before 755
During 756
Ventilation Scan 756
Perfusion Scan 756
After 756
TEST RESULTS AND CLINICAL SIGNIFICANCE 757
RELATED TESTS 757
Meckel Diverticulum Nuclear Scan 757
NORMAL FINDINGS 757
INDICATIONS 757
TEST EXPLANATION 757
PROCEDURE AND PATIENT CARE 758
Before 758
During 758
After 758
TEST RESULTS AND CLINICAL SIGNIFICANCE 758
Octreotide Scan (Carcinoid Nuclear Scan, MIBG Scintigraphy, Neuroendocrine Nuclear Scan) 758
NORMAL FINDINGS 758
INDICATIONS 759
TEST EXPLANATION 759
CONTRAINDICATIONS 759
INTERFERING FACTORS 759
PROCEDURE AND PATIENT CARE 759
Before 759
During 760
After 760
TEST RESULTS AND CLINICAL SIGNIFICANCE 760
Parathyroid Scan (Parathyroid Scintigraphy) 760
NORMAL FINDINGS 760
INDICATIONS 760
TEST EXPLANATION 761
CONTRAINDICATIONS 761
INTERFERING FACTORS 761
PROCEDURE AND PATIENT CARE 761
Before 761
During 761
After 762
TEST RESULTS AND CLINICAL SIGNIFICANCE 762
RELATED TESTS 762
Positron Emission Tomography (PET Scan) 762
NORMAL FINDINGS 762
INDICATIONS 762
TEST EXPLANATION 762
Neurology 764
Cardiology 765
Oncology 765
Bone 766
INTERFERING FACTORS 767
PROCEDURE AND PATIENT CARE 767
Before 767
During 768
After 768
TEST RESULTS AND CLINICAL SIGNIFICANCE 768
RELATED TESTS 768
ProstaScint Scan (Radioimmunoscintigraphy [RIS]) 769
NORMAL FINDINGS 769
INDICATIONS 769
TEST EXPLANATION 769
CONTRAINDICATIONS 769
INTERFERING FACTORS 769
PROCEDURE AND PATIENT CARE 769
Before 769
During 770
After 770
TEST RESULTS AND CLINICAL SIGNIFICANCE 770
RELATED TESTS 770
NORMAL FINDINGS 770
INDICATIONS 770
TEST EXPLANATION 771
Renal Blood Flow (Perfusion) Scan 771
Renal Structural Scan 771
Renal Function Scan (Renogram) 772
Renal Hypertension Scan 772
Renal Obstruction Scan 772
CONTRAINDICATIONS 773
PROCEDURE AND PATIENT CARE 773
Before 773
During 773
After 774
TEST RESULTS AND CLINICAL SIGNIFICANCE 774
RELATED TESTS 775
Salivary Gland Nuclear Imaging (Parotid Gland Nuclear Imaging) 775
NORMAL FINDINGS 775
INDICATIONS 775
TEST EXPLANATION 775
CONTRAINDICATIONS 776
INTERFERING FACTORS 776
PROCEDURE AND PATIENT CARE 776
Before 776
During 776
After 776
TEST RESULTS AND CLINICAL SIGNIFICANCE 776
Scrotal Nuclear Imaging (Scrotal Scan, Testicular Imaging) 777
NORMAL FINDINGS 777
INDICATIONS 777
TEST EXPLANATION 777
PROCEDURE AND PATIENT CARE 777
Before 777
During 777
After 777
TEST RESULTS AND CLINICAL SIGNIFICANCE 778
?Increased Testicular Blood Flow 778
?Decreased Testicular Blood Flow 778
RELATED TEST 778
Sentinel Lymph Node Biopsy (SLNB, Lymphoscintigraphy) 778
NORMAL FINDINGS 778
INDICATIONS 778
TEST EXPLANATION 778
CONTRAINDICATIONS 779
POTENTIAL COMPLICATIONS 779
PROCEDURE AND PATIENT CARE 779
Before 779
DURING 779
After 780
TEST RESULTS AND CLINICAL SIGNIFICANCE 780
Thyroid Scanning (Thyroid Scintiscan) 780
NORMAL FINDINGS 780
INDICATIONS 780
TEST EXPLANATION 780
CONTRAINDICATIONS 782
POTENTIAL COMPLICATIONS 782
INTERFERING FACTORS 782
PROCEDURE AND PATIENT CARE 782
Before 782
During 783
After 783
TEST RESULTS AND CLINICAL SIGNIFICANCE 783
RELATED TESTS 783
Total Blood Volume (TBV, Red Blood Cell [RBC] Volume) 784
NORMAL FINDINGS 784
INDICATIONS 784
TEST EXPLANATION 784
PROCEDURE AND PATIENT CARE 784
Before 784
During 785
After 785
TEST RESULTS AND CLINICAL SIGNIFICANCE 785
?Increased Levels 785
?Decreased Levels 785
RELATED TEST 785
WBC Scan (Inflammatory Scan) 785
NORMAL FINDINGS 785
INDICATIONS 785
TEST EXPLANATION 785
INTERFERING FACTORS 786
PROCEDURE AND PATIENT CARE 786
Before 786
During 786
After 786
TEST RESULTS AND CLINICAL SIGNIFICANCE 787
9 - Stool Tests 788
REASONS FOR PERFORMING STOOL STUDIES 788
PROCEDURAL CARE FOR STOOL STUDIES 789
Before 789
During 789
After 789
REPORTING OF RESULTS 789
Apt Test (Downey Test, Qualitative Fetal Hemoglobin Stool Test, Stool for Swallowed Blood) 789
NORMAL FINDINGS 789
INDICATIONS 789
TEST EXPLANATION 789
PROCEDURE AND PATIENT CARE 790
Before 790
During 790
After 790
TEST RESULTS AND CLINICAL SIGNIFICANCE 790
RELATED TEST 790
Clostridium difficile Testing (C. diff., Clostridial Toxin Assay) 790
NORMAL FINDINGS 790
INDICATIONS 791
TEST EXPLANATION 791
PROCEDURE AND PATIENT CARE 791
Before 791
During 792
After 792
TEST RESULTS AND CLINICAL SIGNIFICANCE 792
RELATED TESTS 792
Fecal Calprotectin 792
NORMAL FINDINGS 792
INDICATIONS 792
TEST EXPLANATION 792
INTERFERING FACTORS 793
PROCEDURE AND PATIENT CARE 793
Before 793
During 793
TEST RESULTS AND CLINICAL SIGNIFICANCE 793
RELATED TESTS 793
Fecal Fat (Fat Absorption, Quantitative Stool Fat Determination) 793
NORMAL FINDINGS 793
INDICATIONS 793
TEST EXPLANATION 794
INTERFERING FACTORS 794
PROCEDURE AND PATIENT CARE 794
Before 794
During 795
After 795
TEST RESULTS AND CLINICAL SIGNIFICANCE 795
?Increased Levels 795
RELATED TEST 795
Lactoferrin 795
NORMAL FINDINGS 795
INDICATIONS 795
TEST EXPLANATION 796
INTERFERING FACTORS 796
PROCEDURE AND PATIENT CARE 796
Before 796
During 796
After 796
TEST RESULTS AND CLINICAL SIGNIFICANCE 796
RELATED TESTS 797
Stool Culture (Stool for Culture and Sensitivity [Stool C&S], Stool for Ova and Parasites [O&P]) 797
NORMAL FINDINGS 797
INDICATIONS 797
TEST EXPLANATION 797
INTERFERING FACTORS 797
PROCEDURE AND PATIENT CARE 798
Before 798
During 798
Tape Test 798
After 798
TEST RESULTS AND CLINICAL SIGNIFICANCE 798
RELATED TEST 798
Stool for Leukocytes (White Blood Cell Stool Test, Fecal Leukocyte Stain, Stool for White Cells) 799
NORMAL FINDINGS 799
INDICATIONS 799
TEST EXPLANATION 799
PROCEDURE AND PATIENT CARE 799
Before 799
During 799
After 799
TEST RESULTS AND CLINICAL SIGNIFICANCE 799
RELATED TESTS 800
Stool for Occult Blood (Stool for OB, Fecal Occult Blood Test [FOBT], Fecal Immunochemical Test [FIT], DNA Stool Sample) 800
NORMAL FINDINGS 800
INDICATIONS 800
TEST EXPLANATION 800
INTERFERING FACTORS 802
PROCEDURE AND PATIENT CARE 802
Before 802
During 803
Hemoccult Slide Test 803
Tablet Test 803
DNA Home Test 803
After 803
TEST RESULTS AND CLINICAL SIGNIFICANCE 803
RELATED TESTS 804
10 - Ultrasound Studies 805
Overview 805
REASONS FOR PERFORMING ULTRASOUND STUDIES 805
PRINCIPLES OF ULTRASONOGRAPHY 806
PROCEDURAL CARE FOR ULTRASONOGRAPHY 808
Before 808
During 808
After 809
INTERFERING FACTORS 809
POTENTIAL COMPLICATIONS 809
REPORTING OF RESULTS 810
NORMAL FINDINGS 810
INDICATIONS 810
TEST EXPLANATION 810
INTERFERING FACTORS 811
PROCEDURE AND PATIENT CARE 812
Before 812
During 812
After 812
TEST RESULTS AND CLINICAL SIGNIFICANCE 813
Kidney 813
Pancreas 813
Gallbladder 814
Liver 814
Bile Ducts 814
Abdominal Aorta 814
Abdominal Cavity 814
RELATED TESTS 814
Breast Ultrasonography (Ultrasound Mammography, Breast Sonogram) 815
NORMAL FINDINGS 815
INDICATIONS 815
TEST EXPLANATION 815
PROCEDURE AND PATIENT CARE 815
Before 815
During 816
After 816
TEST RESULTS AND CLINICAL SIGNIFICANCE 816
RELATED TESTS 817
Carotid Artery Duplex Scan (Carotid Ultrasound) 817
NORMAL FINDINGS 817
INDICATIONS 817
TEST EXPLANATION 817
PROCEDURE AND PATIENT CARE 818
Before 818
During 818
After 818
TEST RESULTS AND CLINICAL SIGNIFICANCE 819
RELATED TEST 819
Contraceptive Device Localization (Intrauterine Device [IUD] Localization) 819
NORMAL FINDINGS 819
INDICATIONS 819
TEST EXPLANATION 819
INTERFERING FACTORS 819
PROCEDURE AND PATIENT CARE 819
Before 819
During 820
After 820
TEST RESULTS AND CLINICAL SIGNIFICANCE 820
Echocardiography (Cardiac Echography, Heart Sonography, Transthoracic Echocardiography [TTE]) 820
NORMAL FINDINGS 820
INDICATIONS 820
TEST EXPLANATION 820
CONTRAINDICATIONS 822
INTERFERING FACTORS 822
PROCEDURE AND PATIENT CARE 822
Before 822
During 822
After 823
TEST RESULTS AND CLINICAL SIGNIFICANCE 823
RELATED TEST 824
Fetal Biophysical Profile (BPP) 824
NORMAL FINDINGS 824
?Critical Values 824
INDICATIONS 824
TEST EXPLANATION 825
INTERFERING FACTORS 826
PROCEDURE AND PATIENT CARE 826
Before 826
During 826
After 826
TEST RESULTS AND CLINICAL SIGNIFICANCE 827
RELATED TESTS 827
Intravascular Ultrasound (IVUS) 827
NORMAL FINDINGS 827
INDICATIONS 827
TEST EXPLANATION 827
INTERFERING FACTORS 828
PROCEDURE AND PATIENT CARE 828
Before 828
During 828
After 828
TEST RESULTS AND CLINICAL SIGNIFICANCE 828
RELATED TEST 829
Ocular and Orbit Ultrasonography 829
NORMAL FINDINGS 829
INDICATIONS 829
TEST EXPLANATION 829
PROCEDURE AND PATIENT CARE 829
Before 829
During 829
After 829
TEST RESULTS AND CLINICAL SIGNIFICANCE 829
NORMAL FINDINGS 830
INDICATIONS 830
TEST EXPLANATION 830
CONTRAINDICATIONS 831
INTERFERING FACTORS 831
PROCEDURE AND PATIENT CARE 832
Before 832
During 832
After 832
TEST RESULTS AND CLINICAL SIGNIFICANCE 832
RELATED TESTS 833
Prostate and Rectal Sonography 834
NORMAL FINDINGS 834
INDICATIONS 834
TEST EXPLANATION 834
CONTRAINDICATIONS 835
INTERFERING FACTORS 835
PROCEDURE AND PATIENT CARE 835
Before 835
During 835
After 835
TEST RESULTS AND CLINICAL SIGNIFICANCE 835
RELATED TEST 836
Scrotal Ultrasonography (Ultrasound of Testes) 836
NORMAL FINDINGS 836
INDICATIONS 836
TEST EXPLANATION 836
PROCEDURE AND PATIENT CARE 837
Before 837
During 837
After 837
TEST RESULTS AND CLINICAL SIGNIFICANCE 837
Thyroid Ultrasonography (Thyroid Echography, Thyroid Sonography) 838
NORMAL FINDINGS 838
INDICATIONS 838
TEST EXPLANATION 838
PROCEDURE AND PATIENT CARE 838
Before 838
During 839
After 839
TEST RESULTS AND CLINICAL SIGNIFICANCE 839
RELATED TEST 839
Transesophageal Echocardiography (TEE) 840
NORMAL FINDINGS 840
INDICATIONS 840
TEST EXPLANATION 840
CONTRAINDICATIONS 841
POTENTIAL COMPLICATIONS 841
PROCEDURE AND PATIENT CARE 842
Before 842
During 842
After 842
TEST RESULTS AND CLINICAL SIGNIFICANCE 842
RELATED TEST 843
Vascular Ultrasound Studies (Venous/Arterial Doppler Ultrasound, Venous/Arterial Duplex Scan) 843
Venous 843
Arterial 843
INDICATIONS 843
TEST EXPLANATION 843
INTERFERING FACTORS 844
PROCEDURE AND PATIENT CARE 844
Before 844
During 844
Venous Doppler Studies 844
Arterial Doppler Studies 845
After 845
TEST RESULTS AND CLINICAL SIGNIFICANCE 845
RELATED TESTS 845
11 - Urine Studies 846
Overview 846
REASONS FOR OBTAINING URINE SPECIMENS 847
TYPES OF URINE SPECIMENS 847
First Morning Specimen 847
Random Urine Specimen 848
Timed Urine Collection 848
Double-Voided Specimen 848
Urine Specimen for Culture and Sensitivity 849
Other Body Fluids 849
COLLECTION METHODS 849
Common Collection Methods 849
Routine Void Specimen 849
Midstream and Clean-Catch Specimens 849
24-Hour Urine Collection 849
Special Collection Methods 850
Urethral Catheterization 850
Suprapubic Aspiration 850
Pediatric Collections 850
TRANSPORT, STORAGE, AND PRESERVATION 851
URINE REAGENT STRIPS 851
REPORTING OF RESULTS 852
Amylase, Urine 852
NORMAL FINDINGS 852
INDICATIONS 852
TEST EXPLANATION 852
INTERFERING FACTORS 853
PROCEDURE AND PATIENT CARE 853
TEST RESULTS AND CLINICAL SIGNIFICANCE 853
?Increased Levels 853
RELATED TESTS 854
Bence-Jones Protein (Free Kappa and Lambda Light Chains) 854
NORMAL FINDINGS 854
INDICATIONS 854
TEST EXPLANATION 854
INTERFERING FACTORS 855
PROCEDURE AND PATIENT CARE 855
TEST RESULTS AND CLINICAL SIGNIFICANCE 855
?Increased Levels 855
RELATED TEST 855
11 Beta-Prostaglandin F(2) Alpha, Urine 855
NORMAL FINDINGS 855
INDICATIONS 856
TEST EXPLANATION 856
PROCEDURE AND PATIENT CARE 856
TEST RESULTS AND CLINICAL SIGNIFICANCE 856
?Increased Levels 856
Bladder Cancer Markers (Bladder Tumor Antigen [BTA], Nuclear Matrix Protein 22 [NMP22]) 856
NORMAL FINDINGS 856
INDICATIONS 857
TEST EXPLANATION 857
INTERFERING FACTORS 857
PROCEDURE AND PATIENT CARE 857
TEST RESULTS AND CLINICAL SIGNIFICANCE 858
?Increased Levels 858
Bone Turnover Markers (BTMs, N-Telopeptide [NTx], Bone Collagen Equivalents [BCEs], Osteocalcin [Bone G1a Protein, BGP, Osteocal... 858
NORMAL FINDINGS 858
INDICATIONS 859
TEST EXPLANATION 859
INTERFERING FACTORS 860
PROCEDURE AND PATIENT CARE 860
TEST RESULTS AND CLINICAL SIGNIFICANCE 860
?Increased Levels 860
?Decreased Levels 861
RELATED TESTS 861
Chloride, Urine (CI) 861
NORMAL FINDINGS 861
INDICATIONS 861
TEST EXPLANATION 861
INTERFERING FACTORS 861
PROCEDURE AND PATIENT CARE 861
TEST RESULTS AND CLINICAL SIGNIFICANCE 862
?Increased Levels 862
?Decreased Levels 862
RELATED TESTS 862
Cortisol, Urine (Hydrocortisone, Urine Cortisol, Free Cortisol) 862
NORMAL FINDINGS 862
INDICATIONS 862
TEST EXPLANATION 862
INTERFERING FACTORS 863
PROCEDURE AND PATIENT CARE 863
TEST RESULTS AND CLINICAL SIGNIFICANCE 863
?Increased Levels 863
?Decreased Levels 863
RELATED TESTS 864
Delta-Aminolevulinic Acid (Aminolevulinic Acid [ALA], δ-ALA) 864
NORMAL FINDINGS 864
?Critical Values 864
INDICATIONS 864
TEST EXPLANATION 864
INTERFERING FACTORS 865
PROCEDURE AND PATIENT CARE 865
TEST RESULTS AND CLINICAL SIGNIFICANCE 865
?Increased Levels 865
RELATED TESTS 865
Glucose, Urine (Urine Sugar) 865
NORMAL FINDINGS 865
INDICATIONS 865
TEST EXPLANATION 865
INTERFERING FACTORS 866
PROCEDURE AND PATIENT CARE 866
TEST RESULTS AND CLINICAL SIGNIFICANCE 867
?Increased Levels 867
RELATED TESTS 867
17-Hydroxycorticosteroids (17-OCHS) 867
NORMAL FINDINGS 867
INDICATIONS 867
TEST EXPLANATION 868
INTERFERING FACTORS 868
PROCEDURE AND PATIENT CARE 868
TEST RESULTS AND CLINICAL SIGNIFICANCE 868
?Increased Levels 868
?Decreased Levels 869
RELATED TEST 869
5-Hydroxindoleacetic Acid (5-HIAA) 869
NORMAL FINDINGS 869
INDICATIONS 869
TEST EXPLANATION 869
INTERFERING FACTORS 869
PROCEDURE AND PATIENT CARE 870
TEST RESULTS AND CLINICAL SIGNIFICANCE 870
?Increased Levels 870
?Decreased Levels 870
17-Ketosteroid (17-KS) 870
NORMAL FINDINGS 870
INDICATIONS 870
TEST EXPLANATION 871
INTERFERING FACTORS 871
PROCEDURE AND PATIENT CARE 871
TEST RESULTS AND CLINICAL SIGNIFICANCE 871
?Increased Levels 871
?Decreased Levels 872
RELATED TEST 872
Microalbumin (MA) 872
NORMAL FINDINGS 872
INDICATION 872
TEST EXPLANATION 873
INTERFERING FACTORS 873
PROCEDURE AND PATIENT CARE 873
TEST RESULTS AND CLINICAL SIGNIFICANCE 874
?Increased Levels 874
Microglobulin (Beta-2 Microglobulin [B2M], Alpha 1 Microglobulin, and Retinol-Binding Protein) 874
NORMAL FINDINGS 874
INDICATIONS 874
TEST EXPLANATION 874
INTERFERING FACTORS 875
PROCEDURE AND PATIENT CARE 875
Before 875
During 875
Blood 875
Urine 875
TEST RESULTS AND CLINICAL SIGNIFICANCE 875
?Increased Urine Levels 875
?Increased Serum Levels 876
RELATED TESTS 876
Nicotine and Metabolites (Nicotine, Cotinine, 3-Hydroxy-Cotinine, Nornicotine, Anabasine) 876
INDICATIONS 877
TEST EXPLANATION 877
INTERFERING FACTORS 878
PROCEDURE AND PATIENT CARE 878
Before 878
During 878
Blood 878
Urine 878
Saliva 878
After 878
TEST RESULTS AND CLINICAL SIGNIFICANCE 878
Osmolality, Urine 878
NORMAL FINDINGS 878
INDICATIONS 879
TEST EXPLANATION 879
PROCEDURE AND PATIENT CARE 879
TEST RESULTS AND CLINICAL SIGNIFICANCE 880
?Increased Levels 880
?Decreased Levels 880
RELATED TESTS 880
Porphyrins and Porphobilinogens (Uroporphyrins, Coproporphyrin, Free Erythrocyte Protoporphyrin [FEP]) 880
NORMAL FINDINGS 880
INDICATIONS 881
TEST EXPLANATION 881
INTERFERING FACTORS 881
PROCEDURE AND PATIENT CARE 882
Porphobilinogens 882
Porphyrins 882
TEST RESULTS AND CLINICAL SIGNIFICANCE 882
RELATED TESTS 882
Potassium, Urine (K) 882
NORMAL FINDINGS 882
INDICATIONS 882
TEST EXPLANATION 883
INTERFERING FACTORS 883
PROCEDURE AND PATIENT CARE 883
TEST RESULTS AND CLINICAL SIGNIFICANCE 883
?Increased Levels 883
?Decreased Levels 883
RELATED TESTS 884
Pregnanediol 884
NORMAL FINDINGS 884
INDICATIONS 884
TEST EXPLANATION 884
INTERFERING FACTORS 885
PROCEDURE AND PATIENT CARE 885
TEST RESULTS AND CLINICAL SIGNIFICANCE 885
?Increased Levels 885
?Decreased Levels 885
RELATED TEST 886
Sodium, Urine (Na) 886
NORMAL FINDINGS 886
INDICATIONS 886
TEST EXPLANATION 886
INTERFERING FACTORS 887
PROCEDURE AND PATIENT CARE 887
TEST RESULTS AND CLINICAL SIGNIFICANCE 887
?Increased Levels 887
?Decreased Levels 887
RELATED TESTS 888
Substance Abuse Testing (Urine Drug Testing, Drug Screening) 888
NORMAL FINDINGS 888
INDICATIONS 888
TEST EXPLANATION 888
INTERFERING FACTORS 890
PROCEDURE AND PATIENT CARE 890
Before 890
During 890
After 890
TEST RESULTS AND CLINICAL SIGNIFICANCE 891
RELATED TEST 891
Toxicology 891
NORMAL FINDINGS 891
INDICATIONS 891
TEST EXPLANATION 891
Commonly Abused Drugs 892
Marijuana (Cannabis) 892
Cocaine (Including Crack) 893
Phencyclidine (PCP) 893
Amphetamines (Especially Methamphetamine) 893
Morphine and Other Narcotic Alkaloids 893
Barbiturates 893
Common Toxins 893
Lead 893
Other Heavy Metals 893
INTERFERING FACTORS 893
PROCEDURE AND PATIENT CARE 893
Before 893
During 893
After 894
TEST RESULTS AND CLINICAL SIGNIFICANCE 894
RELATED TESTS 894
Uric Acid, Urine 894
NORMAL FINDINGS 894
INDICATIONS 894
TEST EXPLANATION 894
INTERFERING FACTORS 895
PROCEDURE AND PATIENT CARE 895
TEST RESULTS AND CLINICAL SIGNIFICANCE 895
?Increased Levels (Uricosuria) 895
?Decreased Levels 895
RELATED TEST 896
Urinalysis (UA) 896
NORMAL FINDINGS 896
INDICATIONS 896
TEST EXPLANATION 897
Laboratory Examination 897
Appearance and Color 897
Odor 898
pH 898
Protein 899
Glucose 899
Specific Gravity 899
Leukocyte Esterase (WBC Esterase) 900
Nitrites 900
Ketones 900
Bilirubin and Urobilinogen 900
Microscopic Examination of Urine Sediment 901
Crystals 901
Casts 901
Hyaline Casts. Hyaline casts are conglomerations of protein and are indicative of proteinuria. A few hyaline casts are normally ... 901
Cellular Casts. Cellular casts are conglomerations of degenerated cells. Various types are described in the following paragraphs... 901
INTERFERING FACTORS 902
Appearance and Color 902
Odor 903
pH 903
Protein 903
Specific Gravity 903
Leukocyte Esterase 903
Ketones 903
Bilirubin and Urobilinogen 904
Crystals 904
WBCs 904
RBCs 904
PROCEDURE AND PATIENT CARE 904
TEST RESULTS AND CLINICAL SIGNIFICANCE 905
APPEARANCE AND COLOR 905
ODOR 905
pH 906
12 - X-Ray Studies 921
Overview 922
REASON FOR PERFORMING X-RAY STUDIES 922
PRINCIPLES OF RADIOLOGY 922
PLAIN RADIOGRAPHY 923
FLUOROSCOPY 923
TOMOGRAPHY 923
CONTRAST STUDIES 923
DIGITAL SUBTRACTION ANGIOGRAPHY 923
RADIATION DOSE 925
RISK OF RADIATION 925
Radiation Associated With Diagnostic Testing 925
CONTRAINDICATIONS 927
POTENTIAL COMPLICATIONS 927
INTERFERING FACTORS 928
PROCEDURE AND PATIENT CARE 928
Before 928
During 929
After 929
REPORTING OF RESULTS 929
Arteriography (Angiography; Renal, Mesenteric, Adrenal, Cerebral, and Lower Extremity Arteriography) 929
NORMAL FINDINGS 929
INDICATIONS 929
TEST EXPLANATION 929
CONTRAINDICATIONS 932
POTENTIAL COMPLICATIONS 932
PROCEDURE AND PATIENT CARE 932
Before 932
During 933
After 934
TEST RESULTS AND CLINICAL SIGNIFICANCE 935
Adrenal Angiography 935
Arteriography of Lower Extremity 935
Brain Arteriography 935
Kidney Arteriography 936
Barium Enema (BE, Lower GI Series) 936
NORMAL FINDINGS 936
INDICATIONS 936
TEST EXPLANATION 936
CONTRAINDICATIONS 937
POTENTIAL COMPLICATIONS 937
INTERFERING FACTORS 937
PROCEDURE AND PATIENT CARE 938
Before 938
During 939
After 940
TEST RESULTS AND CLINICAL SIGNIFICANCE 940
RELATED TESTS 941
Barium Swallow (Esophagogram) 941
NORMAL FINDINGS 941
INDICATIONS 941
TEST EXPLANATION 941
CONTRAINDICATIONS 942
POTENTIAL COMPLICATIONS 942
INTERFERING FACTORS 942
PROCEDURE AND PATIENT CARE 942
Before 942
During 942
After 942
TEST RESULTS AND CLINICAL SIGNIFICANCE 943
RELATED TEST 943
Bone Densitometry (Bone Mineral Content [BMC], Bone Absorptiometry, Bone Mineral Density [BMD], DEXA Scan) 943
NORMAL FINDINGS 943
INDICATIONS 944
TEST EXPLANATION 944
INTERFERING FACTORS 946
PROCEDURE AND PATIENT CARE 946
Before 946
During 946
After 947
TEST RESULTS AND CLINICAL SIGNIFICANCE 947
RELATED TESTS 948
NORMAL FINDINGS 948
INDICATIONS 948
TEST EXPLANATION 948
INTERFERING FACTORS 949
PROCEDURE AND PATIENT CARE 949
Before 949
During 949
After 949
TEST RESULTS AND CLINICAL SIGNIFICANCE 949
Cardiac Catheterization (Coronary Angiography, Angiocardiography, Ventriculography) 950
NORMAL FINDINGS 950
INDICATIONS 950
TEST EXPLANATION 950
CONTRAINDICATIONS 953
POTENTIAL COMPLICATIONS 953
PROCEDURE AND PATIENT CARE 953
Before 953
During 954
After 955
TEST RESULTS AND CLINICAL SIGNIFICANCE 955
RELATED TESTS 956
Chest X-Ray (CXR) 956
NORMAL FINDINGS 956
INDICATIONS 956
TEST EXPLANATION 956
CONTRAINDICATIONS 959
INTERFERING FACTORS 959
PROCEDURE AND PATIENT CARE 960
Before 960
During 960
After 960
TEST RESULTS AND CLINICAL SIGNIFICANCE 960
Lung 960
Heart 961
Chest Wall 961
Diaphragm 961
Mediastinum 961
RELATED TEST 962
NORMAL FINDINGS 962
INDICATIONS 962
TEST EXPLANATION 962
CONTRAINDICATIONS 964
POTENTIAL COMPLICATIONS 965
INTERFERING FACTORS 965
PROCEDURE AND PATIENT CARE 965
Before 965
During 965
After 967
TEST RESULTS AND CLINICAL SIGNIFICANCE 967
Liver 967
Pancreas 967
Spleen 967
Gallbladder/Biliary System 967
Kidneys 967
Adrenal gland 967
GI Tract 967
Uterus, Fallopian Tubes, Ovaries 967
Prostate 968
Retroperitoneum 968
Peritoneum 968
RELATED TEST 968
NORMAL FINDINGS 968
INDICATIONS 968
TEST EXPLANATION 968
CONTRAINDICATIONS 969
POTENTIAL COMPLICATIONS 969
PROCEDURE AND PATIENT CARE 969
Before 969
During 970
After 970
TEST RESULTS AND CLINICAL SIGNIFICANCE 970
RELATED TEST 971
Computed Tomography, Chest (Chest CT Scan; Helical/Spiral CT Scan, Chest) 971
NORMAL FINDINGS 971
INDICATIONS 971
TEST EXPLANATION 971
CONTRAINDICATIONS 972
POTENTIAL COMPLICATIONS 973
PROCEDURE AND PATIENT CARE 973
Before 973
During 973
After 973
TEST RESULTS AND CLINICAL SIGNIFICANCE 974
Lung 974
Heart 974
Chest Wall 974
Diaphragm 974
Mediastinum 974
RELATED TEST 975
Computed Tomography, Heart (Coronary CT Angiography, Coronary Calcium Score) 975
NORMAL FINDINGS 975
INDICATIONS 975
TEST EXPLANATION 975
CONTRAINDICATIONS 977
POTENTIAL COMPLICATIONS 977
PROCEDURE AND PATIENT CARE 977
Before 977
During 977
After 978
TEST RESULTS AND CLINICAL SIGNIFICANCE 978
RELATED TESTS 978
Cystography (Cystourethrography, Voiding, Cystography, Voiding Cystourethrography) 978
NORMAL FINDINGS 978
INDICATIONS 978
TEST EXPLANATION 979
CONTRAINDICATIONS 979
POTENTIAL COMPLICATIONS 979
PROCEDURE AND PATIENT CARE 979
Before 979
During 979
After 980
TEST RESULTS AND CLINICAL SIGNIFICANCE 980
Dental X-Ray (Dental Radiography) 981
NORMAL FINDINGS 981
INDICATIONS 981
TEST EXPLANATION 981
INTERFERING FACTORS 981
CONTRAINDICATIONS 981
PROCEDURE AND PATIENT CARE 982
Before 982
During 982
After 982
TEST RESULTS AND CLINICAL SIGNIFICANCE 982
Hysterosalpingography (Uterotubography, Uterosalpingography, Hysterogram) 982
NORMAL FINDINGS 982
INDICATIONS 982
TEST EXPLANATION 982
CONTRAINDICATIONS 983
POTENTIAL COMPLICATIONS 983
INTERFERING FACTORS 983
PROCEDURE AND PATIENT CARE 983
Before 983
During 984
After 984
TEST RESULTS AND CLINICAL SIGNIFICANCE 984
Kidney, Ureter, and Bladder X-Ray (KUB, Flat Plate of the Abdomen, Plain Film of the Abdomen, Scout Film) 985
NORMAL FINDINGS 985
INDICATIONS 985
TEST EXPLANATION 985
CONTRAINDICATIONS 985
INTERFERING FACTORS 986
PROCEDURE AND PATIENT CARE 986
Before 986
During 986
After 987
TEST RESULTS AND CLINICAL SIGNIFICANCE 987
RELATED TEST 987
Mammography (Mammogram, Digital Mammography) 987
Breast Imaging Reporting and Database System (BI-RADS®) 987
INDICATIONS 987
Screening Mammography Guidelines 988
National Institutes of Health 988
American Cancer Society 988
U.S. Preventive Services Task Force 988
When to Stop Screening 988
Diagnostic Mammography 988
TEST EXPLANATION 989
CONTRAINDICATIONS 991
INTERFERING FACTORS 991
PROCEDURE AND PATIENT CARE 991
Before 991
During 992
After 992
TEST RESULTS AND CLINICAL SIGNIFICANCE 992
RELATED TESTS 993
Myelography (Myelogram, CT Myelography) 993
NORMAL FINDINGS 993
INDICATIONS 993
TEST EXPLANATION 993
CONTRAINDICATIONS 994
POTENTIAL COMPLICATIONS 994
PROCEDURE AND PATIENT CARE 994
Before 994
During 994
After 995
TEST RESULTS AND CLINICAL SIGNIFICANCE 995
RELATED TEST 995
Obstruction Series 995
NORMAL FINDINGS 995
INDICATIONS 996
TEST EXPLANATION 996
CONTRAINDICATIONS 996
INTERFERING FACTORS 996
PROCEDURE AND PATIENT CARE 996
Before 996
During 997
After 997
TEST RESULTS AND CLINICAL SIGNIFICANCE 997
RELATED TEST 997
Percutaneous Transhepatic Cholangiography (PTC, PTHC) 997
NORMAL FINDINGS 997
INDICATIONS 998
TEST EXPLANATION 998
CONTRAINDICATIONS 998
POTENTIAL COMPLICATIONS 999
INTERFERING FACTORS 999
PROCEDURE AND PATIENT CARE 999
Before 999
During 999
After 999
TEST RESULTS AND CLINICAL SIGNIFICANCE 1000
RELATED TEST 1001
NORMAL FINDINGS 1001
INDICATIONS 1001
TEST EXPLANATION 1001
CONTRAINDICATIONS 1002
POTENTIAL COMPLICATIONS 1002
INTERFERING FACTORS 1003
PROCEDURE AND PATIENT CARE 1003
Before 1003
During 1003
Intravenous Pyelography 1003
Retrograde Pyelography 1004
Antegrade Pyelography 1004
After 1004
TEST RESULTS AND CLINICAL SIGNIFICANCE 1004
RELATED TESTS 1005
Sialography 1005
NORMAL FINDINGS 1005
INDICATIONS 1005
TEST EXPLANATION 1005
CONTRAINDICATIONS 1006
POTENTIAL COMPLICATIONS 1006
PROCEDURE AND PATIENT CARE 1006
Before 1006
During 1006
After 1006
TEST RESULTS AND CLINICAL SIGNIFICANCE 1006
Skull X-Ray 1007
NORMAL FINDINGS 1007
INDICATIONS 1007
TEST EXPLANATION 1007
PROCEDURE AND PATIENT CARE 1008
Before 1008
During 1008
After 1008
TEST RESULTS AND CLINICAL SIGNIFICANCE 1008
RELATED TEST 1009
Small Bowel Follow-Through (SBF, Small Bowel Enema) 1009
NORMAL FINDINGS 1009
INDICATIONS 1009
TEST EXPLANATION 1009
CONTRAINDICATIONS 1010
POTENTIAL COMPLICATIONS 1010
INTERFERING FACTORS 1010
PROCEDURE AND PATIENT CARE 1011
Before 1011
During 1011
Small Bowel Enema 1011
After 1011
TEST RESULTS AND CLINICAL SIGNIFICANCE 1011
RELATED TEST 1012
Spinal X-Rays (Cervical, Thoracic, Lumbar, Sacral, or Coccygeal X-Ray Studies) 1012
NORMAL FINDINGS 1012
INDICATIONS 1012
TEST EXPLANATION 1012
CONTRAINDICATIONS 1013
PROCEDURE AND PATIENT CARE 1013
Before 1013
During 1013
After 1013
TEST RESULTS AND CLINICAL SIGNIFICANCE 1014
RELATED TESTS 1014
Swallowing Examination (Videofluoroscopy Swallowing Examination) 1014
NORMAL FINDINGS 1014
INDICATIONS 1014
TEST EXPLANATION 1014
CONTRAINDICATIONS 1015
PROCEDURE AND PATIENT CARE 1015
Before 1015
During 1015
After 1015
TEST RESULTS AND CLINICAL SIGNIFICANCE 1015
RELATED TEST 1015
T-Tube and Operative Cholangiography 1015
NORMAL FINDINGS 1015
INDICATIONS 1015
TEST EXPLANATION 1016
POTENTIAL COMPLICATIONS 1016
INTERFERING FACTORS 1016
PROCEDURE AND PATIENT CARE 1016
Before 1016
During 1016
Operative Cholangiogram 1016
T-Tube Cholangiogram 1017
After 1017
TEST RESULTS AND CLINICAL SIGNIFICANCE 1017
RELATED TESTS 1017
Upper Gastrointestinal Tract X-Ray (Upper GI Series, UGI) 1017
NORMAL FINDINGS 1017
INDICATIONS 1017
TEST EXPLANATION 1018
CONTRAINDICATIONS 1018
POTENTIAL COMPLICATIONS 1018
INTERFERING FACTORS 1018
PROCEDURE AND PATIENT CARE 1019
Before 1019
During 1019
After 1020
TEST RESULTS AND CLINICAL SIGNIFICANCE 1020
RELATED TEST 1021
Venography (Phlebography, Venogram) 1021
NORMAL FINDINGS 1021
INDICATIONS 1021
TEST EXPLANATION 1021
CONTRAINDICATIONS 1021
POTENTIAL COMPLICATIONS 1022
PROCEDURE AND PATIENT CARE 1022
Before 1022
During 1022
After 1023
TEST RESULTS AND CLINICAL SIGNIFICANCE 1023
RELATED TESTS 1023
13 - Miscellaneous Studies 1024
Overview 1024
Allergy Skin Testing 1024
NORMAL FINDINGS 1024
INDICATIONS 1025
TEST EXPLANATION 1025
CONTRAINDICATIONS 1025
POTENTIAL COMPLICATIONS 1026
INTERFERING FACTORS 1026
PROCEDURE AND PATIENT CARE 1026
Before 1026
During 1026
Prick-Puncture Method (Scratch Test) 1026
Intradermal Method 1026
Patch Method 1027
After 1027
TEST RESULTS AND CLINICAL SIGNIFICANCE 1027
Allergy-Related Diseases 1027
RELATED TEST 1027
Bioterrorism Infectious Agents Testing (Botulism, Anthrax, Hemorrhagic Fever, Plague, Smallpox, Tularemia, Brucellosis) 1027
NORMAL FINDINGS 1027
INDICATIONS 1028
TEST EXPLANATION 1028
Botulism Infection 1028
Anthrax 1029
Hemorrhagic Fever (Yellow Fever) 1029
Plague 1029
Brucellosis 1030
Smallpox 1030
Tularemia 1030
PROCEDURE AND PATIENT CARE 1030
Before 1030
During 1031
After 1031
TEST RESULTS AND CLINICAL SIGNIFICANCE 1031
Breast Cancer Genomics (Oncotype DX Genotyping, MammaPrint) 1031
NORMAL FINDINGS 1031
INDICATIONS 1031
TEST EXPLANATION 1031
CONTRAINDICATIONS 1032
PROCEDURE AND PATIENT CARE 1032
Before 1032
During 1032
After 1032
TEST RESULTS AND CLINICAL SIGNIFICANCE 1032
RELATED TESTS 1033
Cell Culture Drug Resistance Testing (CCDRT, Chemosensitivity Assay, Drug Response Assay) 1033
NORMAL FINDINGS 1033
INDICATIONS 1033
TEST EXPLANATION 1033
PROCEDURE AND PATIENT CARE 1033
Before 1033
During 1033
After 1033
TEST RESULTS AND CLINICAL SIGNIFICANCE 1033
Chorionic Villus Sampling (CVS, Chorionic Villus Biopsy [CVB]) 1034
NORMAL FINDINGS 1034
INDICATIONS 1034
TEST EXPLANATION 1034
POTENTIAL COMPLICATIONS 1034
PROCEDURE AND PATIENT CARE 1034
Before 1034
During 1035
After 1035
TEST RESULTS AND CLINICAL SIGNIFICANCE 1036
RELATED TESTS 1036
NORMAL FINDINGS 1036
INDICATIONS 1036
TEST EXPLANATION 1036
PROCEDURE AND PATIENT CARE 1037
Before 1037
During 1037
After 1037
TEST RESULTS AND CLINICAL SIGNIFICANCE 1038
RELATED TEST 1038
Fluorescein Angiography (FA, Ocular Photography) 1038
NORMAL FINDINGS 1038
INDICATIONS 1038
TEST EXPLANATION 1038
POTENTIAL COMPLICATIONS 1039
PROCEDURE AND PATIENT CARE 1039
Before 1039
During 1039
After 1040
TEST RESULTS AND CLINICAL SIGNIFICANCE 1040
?Increased Levels 1040
?Decreased Levels 1040
Genetic Testing (Breast Cancer [BRCA] and Ovarian Cancer, Colon Cancer, Cardiovascular Disease, Tay-Sachs Disease, Cystic Fibros... 1040
NORMAL FINDINGS 1040
INDICATIONS 1040
TEST EXPLANATION 1040
Breast Cancer and Ovarian Cancer Genetic Testing 1041
Colon Cancer Genetic Testing 1042
Cardiovascular Disease Genetic Testing 1043
Tay-Sachs Disease Genetic Testing 1044
Cystic Fibrosis Genetic Testing 1044
Melanoma Genetic Testing 1045
Hemochromatosis Genetic Testing 1045
Thyroid Cancer Genetic Testing 1046
Paternity Genetic Testing (Parentage Analysis) 1046
Forensic Genetic Testing 1047
CONTRAINDICATIONS 1047
PROCEDURE AND PATIENT CARE 1047
Before 1047
During 1047
After 1048
TEST RESULTS AND CLINICAL SIGNIFICANCE 1048
RELATED TESTS 1048
Helicobacter pylori Testing (Campylobacter pylori, Anti–Helicobacter pylori Immunoglobulin G [IgG] Antibody, Campylobacter-Like ... 1048
IgM 1048
IgG 1048
Breath Test 1048
Stool Test 1048
INDICATIONS 1049
TEST EXPLANATION 1049
INTERFERING FACTORS 1050
PROCEDURE AND PATIENT CARE 1050
Before 1050
During 1050
After 1051
TEST RESULTS AND CLINICAL SIGNIFICANCE 1051
?Increased Levels 1051
RELATED TESTS 1051
Laboratory Genetics 1051
NORMAL FINDINGS 1051
INDICATIONS 1051
TEST EXPLANATION 1051
CONTRAINDICATIONS 1052
PROCEDURE AND PATIENT CARE 1053
Before 1053
During 1053
After 1053
TEST RESULTS AND CLINICAL SIGNIFICANCE 1053
Related Tests 1053
Genetic Testing (p. 1040); Breast Cancer Tumor Analysis (p. 652) 1053
Magnetic Resonance Imaging (MRI, Nuclear Magnetic Resonance Imaging [NMRI]) 1053
NORMAL FINDINGS 1053
INDICATIONS 1053
TEST EXPLANATION 1053
POTENTIAL COMPLICATIONS 1057
CONTRAINDICATIONS 1057
INTERFERING FACTORS 1058
PROCEDURE AND PATIENT CARE 1058
Before 1058
During 1059
After 1060
TEST RESULTS AND CLINICAL SIGNIFICANCE 1060
Brain 1060
Heart 1060
Breast 1061
Gastrointestinal 1061
Other 1061
RELATED TEST 1061
Oximetry (Pulse Oximetry, Ear Oximetry, Oxygen Saturation) 1061
NORMAL FINDINGS 1061
?Critical Values 1062
INDICATIONS 1062
TEST EXPLANATION 1062
INTERFERING FACTORS 1062
PROCEDURE AND PATIENT CARE 1063
Before 1063
During 1063
After 1063
TEST RESULTS AND CLINICAL SIGNIFICANCE 1063
?Increased Levels 1063
?Decreased Levels 1063
RELATED TESTS 1064
Pulmonary Function Tests (PFTs) 1064
NORMAL FINDINGS 1064
INDICATIONS 1065
TEST EXPLANATION 1065
CONTRAINDICATIONS 1067
POTENTIAL COMPLICATIONS 1067
PROCEDURE AND PATIENT CARE 1068
Before 1068
During 1068
Spirometry and Airflow Rates 1068
Gas Exchange: Diffusing Capacity of Lung (DL) 1068
Inhalation Tests (Bronchial Provocation Studies) 1069
After 1069
TEST RESULTS AND CLINICAL SIGNIFICANCE 1069
RELATED TESTS 1070
Sleep Studies (Polysomnography [PSG], Multiple Sleep Latency Tests [MSLT], Multiple Wake Test [MWT]) 1070
NORMAL FINDINGS 1070
INDICATIONS 1070
TEST EXPLANATION 1070
INTERFERING FACTORS 1072
PROCEDURE AND PATIENT CARE 1073
Before 1073
During 1073
Multiple Sleep Latency Testing 1073
Multiple Wake Testing 1073
After 1073
TEST RESULTS AND CLINICAL SIGNIFICANCE 1073
Tuberculin Skin Testing (TST, Tuberculin Test, Mantoux Test, PPD Test) 1074
NORMAL FINDINGS 1074
INDICATIONS 1074
TEST EXPLANATION 1074
CONTRAINDICATIONS 1076
INTERFERING FACTORS 1076
PROCEDURE AND PATIENT CARE 1076
Before 1076
During 1076
After 1077
TEST RESULTS AND CLINICAL SIGNIFICANCE 1077
Positive Results 1077
Negative Results 1077
RELATED TESTS 1077
Urea Breath Test (UBT, H. pylori Breath Test) 1077
NORMAL FINDINGS 1077
INDICATIONS 1078
TEST EXPLANATION 1078
INTERFERING FACTORS 1078
PROCEDURE AND PATIENT CARE 1078
Before 1078
During 1078
After 1079
TEST RESULTS AND CLINICAL SIGNIFICANCE 1079
RELATED TESTS 1079
Bibliography 1080
Illustration Credits 1083
A - ALPHABETICAL LIST OF TESTS 1084
A 1084
B 1085
C 1085
D 1086
E 1087
F 1087
G 1088
H 1088
I 1088
K 1089
L 1089
M 1089
N 1090
O 1090
P 1090
Q 1091
R 1091
S 1091
T 1092
U 1093
V 1093
W 1093
X 1093
Z 1093
B - PANEL TESTING 1094
CARDIAC RISK PREDICTORS 1094
COAGULATION PROFILE 1094
COMPLETE BLOOD COUNT 1094
DISSEMINATED INTRAVASCULAR COAGULATION (DIC) SCREEN 1094
ELECTROLYTES 1094
LIPID PROFILE 1094
LIVER PROFILE 1094
METABOLIC ASSAY 1094
RENAL FUNCTION 1095
THYROID FUNCTION STUDIES 1095
C - ABBREVIATIONS FOR DIAGNOSTIC AND LABORATORY TESTS 1096
A 1096
B 1096
C 1096
D 1096
E 1097
F 1097
G 1097
H 1097
I 1097
K 1097
L 1098
M 1098
N 1098
O 1098
P 1098
R 1098
S 1098
T 1099
U 1099
V 1099
W 1099
Index 1100
A 1100
B 1104
C 1106
D 1110
E 1111
F 1113
G 1114
H 1116
I 1118
J 1120
K 1120
L 1120
M 1121
N 1123
O 1124
P 1125
Q 1128
R 1128
S 1130
T 1132
U 1134
V 1135
W 1136
X 1137
Y 1137
Z 1137
IBC ES2