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Skin Disease E-Book

Skin Disease E-Book

Thomas P. Habif | M. Shane Chapman | James G. H. Dinulos | Kathryn A. Zug

(2017)

Additional Information

Book Details

Abstract

Get practical guidance from renowned dermatologist Dr. Thomas Habif and his expert team of co-authors in this user-friendly, focused text. Written specifically for the non-specialist, this easy-to-follow reference offers precisely the diagnostic and treatment information you need to quickly identify the 250 skin disorders you’re most likely to see. It’s an ideal resource for any medical practitioner who’d rather treat than refer patients with skin disease, as well as an excellent review for board preparation.

  • Comprehensive yet concise, bullet-point format provides classification of primary, secondary, and special lesions, pediatric considerations, clinical pearls to guide decision making, and more.
  • Disorders Index at the front of the book speeds you quickly to a desired topic, and the dermatologic drug formulary and "differential diagnosis by anatomical region and lesion" guide provide rapid access to essential clinical information.
  • Easy-to-understand schematics indicate disease distribution across the body (from rare to common) for each key disorder.
  • Updated with the latest therapy options and expanded coverage of key topics, including drug reactions and tropical disease.
  • Hundreds of new and never-before-published images (more than 1,000 photographs in all) clearly depict how skin disorders present at different stages.

Table of Contents

Section Title Page Action Price
Front Cover cover
Disorders Index IFC2
Expert Consult page ii
Skin Disease iii
Copyright Page iv
Table Of Contents v
1 Topical Therapy 1
Basic Principles of Treatment 1
Maintaining the Skin Barrier 2
Skin Cleansing 2
Skin Bathing and Soaking 2
Skin Moisturization 2
Examples of Lubricating Creams and Lotions 3
Thicker Creams and Ointments 3
Lighter Creams 3
Lighter Lotions 3
Topical Formulations 3
Topical Application and Dosing 4
Wet Dressings 4
Benefits of Wet Dressings 4
Topical Corticosteroids 6
Description 6
Generic Versus Brand Names 6
Corticosteroid Potency: Groups I to VII 6
Choosing the Appropriate Strength 6
Prescribing Topical Corticosteroids 6
Dosing Schedules 6
Superpotent Topical Corticosteroids (Group I) 6
Groups II to VII Topical Corticosteroids 6
Methods of Application (Simple and Occlusive) 7
Simple 7
Occlusive 7
Method of Occlusion 7
Systemic Absorption 8
Steroid–Antibiotic Mixtures 8
Adverse Reactions 8
2 Eczema 12
Acute Eczematous Inflammation 12
Description 12
History 12
Skin Findings 12
Laboratory 12
Course and Prognosis 12
Management 12
Pearls 13
Rhus Dermatitis (Poison Ivy, Poison Oak, Poison Sumac) 15
Description 15
History 15
Skin Findings 15
Course and Prognosis 15
Discussion 15
Management 15
Pearls 17
Subacute Eczematous Inflammation (Subacute Eczema) 19
Description 19
History 19
Skin Findings 19
Etiology and Clinical Presentation 19
Treatment 19
Steroids and Other Nonsteroid Topical Prescription Therapies 19
Moisturizers 20
Antibiotics 20
Pearls 22
Chronic Eczematous Inflammation 25
Description 25
History 25
Skin Findings 25
Etiology and Clinical Presentation 25
Treatment 25
Topical Steroids 27
Systemic Therapy 27
Pearls 27
Lichen Simplex Chronicus 28
Description 28
History 28
Skin Findings 28
Laboratory 28
Course and Prognosis 28
Treatment 28
Discussion 29
Pearls 29
Hand Eczema 32
Description 32
History 32
Exogenous Factors 32
Endogenous Factors 32
Skin Findings 32
Nonskin Findings 32
Course and Prognosis 32
Treatment 35
Discussion 35
Pearls 35
Asteatotic Eczema 38
Description 38
History 38
Skin Findings 38
Nonskin Findings 38
Laboratory 38
Course and Prognosis 38
Discussion 39
Management 39
Pearls 40
Chapped, Fissured Feet 42
Description 42
History 42
Skin Findings 42
Discussion 42
Differential Diagnosis 42
Treatment 42
Pearls 42
Allergic Contact Dermatitis 45
Description 45
History 45
Skin Findings 45
Laboratory 46
Differential Diagnosis 48
Treatment 48
Pearls 49
Irritant Contact Dermatitis 51
Description 51
History 51
Skin Findings 51
Laboratory 52
Differential Diagnosis 52
Treatment 53
Pearls 54
Fingertip Eczema 55
Description 55
History 55
Etiology 55
Skin Findings 55
Course and Prognosis 55
Discussion and Differential Diagnosis 55
Management 55
Pearls 55
Keratolysis Exfoliativa 58
Description 58
History 58
Skin Findings 58
Course 58
Treatment 58
Pearls 58
Nummular Eczema 60
Description 60
History 60
Skin Findings 60
Laboratory 60
Differential Diagnosis 60
Course and Prognosis 60
Treatment 60
Discussion 61
Pearls 61
Pompholyx 63
Description 63
History 63
Skin Findings 63
Course and Prognosis 63
Differential Diagnosis 63
Management 63
Discussion 64
Pearls 64
Prurigo Nodularis 65
Description 65
History 65
Skin Findings 65
Laboratory 65
Differential Diagnosis 65
Course and Prognosis 65
Treatment 66
Discussion 67
Pearls 67
Stasis Dermatitis 68
Description 68
History 68
Skin Findings 68
Laboratory 68
Treatment 68
Differential Diagnosis 69
Pearls 69
Venous Leg Ulcers 71
Description 71
History 71
Skin Findings 71
Laboratory 71
Differential Diagnosis 71
Treatment 71
Control of Chronic Venous Insufficiency 71
Ulcer Therapy 72
When to Refer 73
Pearls 73
Atopic Dermatitis 74
Description 74
Major Criteria (Four Required for Diagnosis) 74
Minor (or Less Specific) Features 74
History 74
Skin Findings 74
Infantile Phase (2 Months to 2 Years) 74
Childhood Phase (2–12 Years) 74
Adult Phase (12 Years to Adult) 74
Complications 75
Nonskin Findings 75
Laboratory 75
Differential Diagnosis 75
Treatment 76
Severe Atopic Dermatitis 76
Pearls 77
Autosomal Dominant Ichthyosis Vulgaris 79
Description 79
History 79
Skin Findings 79
Laboratory 79
Differential Diagnosis 79
Treatment 79
Pearls 80
Keratosis Pilaris 81
Description 81
History 81
Skin Findings 81
Laboratory 81
Differential Diagnosis 81
Treatment 81
Pearls 81
Pityriasis Alba 83
Description 83
History 83
Skin Findings 83
Laboratory 83
Differential Diagnosis 83
Treatment 83
Pearls 83
3 Urticaria 85
Acute Urticaria 85
Description 85
History 85
Skin Findings 85
Laboratory and Testing 85
Differential Diagnosis 85
Treatment 85
Pearls 86
Chronic Urticaria 87
Description 87
History 87
Skin Findings 87
Laboratory and Testing 87
Differential Diagnosis 88
Treatment 88
Pearls 89
Physical Urticaria 90
Description 90
History 90
Skin Findings 90
Tests 90
Differential Diagnosis 90
Treatment 91
Angioedema 92
Description 92
History 92
Skin Symptoms 92
Laboratory and Testing 92
Treatment 93
Pearls 93
Mastocytosis (Urticaria Pigmentosa) 94
Description 94
History 94
Skin Findings 94
Laboratory and Testing 94
Differential Diagnosis 95
Treatment 95
Pearls 95
Pruritic Urticarial Papules and Plaques of Pregnancy 98
Description 98
History 98
Skin Findings 98
Laboratory and Testing 98
Course and Prognosis 98
Discussion 98
Treatment 99
4 Acne, Rosacea, and Related Disorders 101
Acne 101
Description 101
History 101
Skin Findings 101
Nonskin Findings 101
Laboratory and Biopsy 101
Differential Diagnosis 102
Course and Prognosis 102
Treatment 102
Skin Sensitivity 102
Noninflamed Blocked Pores (Comedones—Blackheads and Whiteheads) 103
Inflamed Pores (Papules and Pustules) 103
Inflamed Nodules and Cysts (Nodulocystic Acne) 105
Changes in Pigment and Scarring 105
When to Refer 105
Pearls 106
Perioral Dermatitis 108
Description 108
History 108
Skin Findings 108
Differential Diagnosis 108
Course and Prognosis 108
Treatment 108
Pearls 109
Rosacea (Acne Rosacea) 110
Description 110
History 110
Skin Findings 110
Nonskin Findings 110
Laboratory and Biopsy 110
Differential Diagnosis 110
Course and Prognosis 110
Treatment 110
Pearls 112
Hidradenitis Suppurativa 114
Description 114
History 114
Skin Findings 114
Laboratory 114
Differential Diagnosis 114
Course and Prognosis 114
Treatment 115
Pearls 115
Hyperhidrosis 118
Definition 118
History 118
Skin Findings 118
Nonskin Findings 118
Laboratory and Biopsy 118
Differential Diagnosis 118
Course and Prognosis 118
Treatment 118
5 Psoriasis and Other Papulosquamous Diseases 120
Psoriasis 120
Description 120
History 120
Skin Findings 120
Chronic Plaque Psoriasis 120
Guttate Psoriasis 122
Inverse (Intertriginous) Psoriasis 122
Erythrodermic Psoriasis 123
Pustular Psoriasis 123
Nail Disease 123
Joint Disease 123
Laboratory 124
Differential Diagnosis 125
Treatment 125
Topical Therapy 125
Phototherapy 126
Systemic Therapy 127
Seborrheic Dermatitis 130
Description 130
History 130
Skin Findings 130
Laboratory 130
Differential Diagnosis 130
Treatment 130
Grover’s Disease (Transient Acantholytic Dermatosis) 135
Description 135
History 135
Skin Findings 135
Laboratory 135
Differential Diagnosis 135
Treatment 135
Pityriasis Rosea 136
Description 136
History 136
Skin Findings 136
Laboratory 136
Differential Diagnosis 137
Treatment 137
Pearls 137
Lichen Planus 139
Description 139
History 139
Skin Findings 139
Papular Lichen Planus 143
Hypertrophic Lichen Planus 143
Follicular Lichen Planus 143
Mucosal Lichen Planus 143
Nail Lichen Planus 143
Laboratory 143
Differential Diagnosis 144
Treatment 144
When to Refer 144
Pearls 144
Lichen Sclerosus 146
Description 146
History 146
Skin Findings 146
Laboratory 146
Differential Diagnosis 146
Treatment 147
Pearls 148
Pityriasis Lichenoides et Varioliformis Acuta and Pityriasis Lichenoides Chronica 150
Description 150
History 150
Skin Findings 150
Laboratory 150
Differential Diagnosis 150
Treatment 150
6 Bacterial Infections 152
Impetigo 152
Description 152
History 152
Skin Findings 152
Bullous Impetigo 152
Nonbullous Impetigo (Crusted) 152
Nonskin Findings 152
Laboratory 152
Differential Diagnosis 153
Course and Prognosis 153
Treatment 153
Discussion 154
Cellulitis 156
Description 156
History 156
Skin Findings 156
Laboratory 156
Differential Diagnosis 156
Treatment 157
Secondary Bacterial Cellulitis From Pre-existing Wounds, Trauma, or Skin Lesions 157
Pearls 157
Erysipelas 160
Description 160
History 160
Skin Findings 160
Nonskin Findings 160
Laboratory 160
Course and Prognosis 161
Discussion 161
Treatment 161
Pearls 161
Folliculitis 163
Description 163
History 163
Skin Findings 163
Laboratory 163
Course and Prognosis 163
Discussion 163
Treatment 164
Pearls 164
Pseudofolliculitis Barbae (Razor Bumps, Ingrown Hairs) 165
Description 165
History 165
Skin Findings 165
Laboratory 165
Differential Diagnosis 165
Treatment 165
Shaving Instructions 166
Pearls 166
Furuncles and Carbuncles 168
Description 168
History 168
Skin Findings 168
Nonskin Findings 168
Laboratory 168
Differential Diagnosis 168
Course and Prognosis 168
Treatment 169
Furuncles and Carbuncles 169
Recurrent Furuncles and Carbuncles 169
Pearls 170
Pseudomonas Folliculitis 171
Description 171
History 171
Skin Findings 171
Nonskin Findings 171
Laboratory 171
Differential Diagnosis 171
Treatment 171
Preventative Measures 171
Otitis Externa 173
Description 173
History 173
Skin Findings 173
Nonskin Findings 173
Laboratory 173
Course and Prognosis 173
Discussion 174
Treatment 175
Pearls 175
7 Sexually Transmitted Infections 177
Syphilis 177
Description 177
History 177
Primary Syphilis 177
Secondary Syphilis 177
Latent Syphilis 177
Tertiary Syphilis 178
Congenital Syphilis 178
Skin Findings 179
Primary Syphilis 179
Secondary Syphilis 179
Latent Syphilis 179
Tertiary Syphilis 179
Laboratory and Testing 180
Differential Diagnosis 181
Primary Syphilis 181
Secondary Syphilis 181
Treatment 181
Chancroid 183
Description 183
History 183
Skin Findings 183
Nonskin Findings 183
Laboratory 183
Differential Diagnosis 183
Treatment 183
Pearls 183
Genital Warts (Condyloma Acuminata) 185
Description 185
History 185
Skin Findings 185
Differential Diagnosis 185
Treatment 186
Pearls 188
Genital Herpes Simplex 190
Description 190
History 190
Primary Infection 190
Recurrent Infection 190
Skin Findings 190
Laboratory and Testing 194
Differential Diagnosis 194
Treatment 194
Counseling 194
Systemic Therapy 194
Primary Infection 194
Recurrent Infection 194
Long-Term Suppressive Therapy 195
Reducing the Risk for Transmission 195
Pubic Lice (Pediculosis Pubis) 197
Description 197
History 197
Skin Findings 197
Standard Treatments 197
Nit Removal 198
Molluscum Contagiosum 199
Description 199
History 199
Skin Findings 199
Differential Diagnosis 199
Treatment 199
8 Viral Infections 203
Warts (Verruca Vulgaris) 203
Description 203
History 203
Skin Findings 203
Laboratory 203
Course and Prognosis 203
Treatment 204
Pearls 206
Flat Warts 210
Description 210
History 210
Skin Findings 210
Course and Prognosis 210
Treatment 210
Pearls 210
Plantar Warts 212
Description 212
Skin Findings 212
Laboratory 212
Course and Prognosis 212
Treatment 212
Pearls 212
Molluscum Contagiosum 214
Description 214
History 214
Skin Findings 214
Laboratory 214
Course and Prognosis 215
Differential Diagnosis 215
Treatment 215
Pearls 216
Herpes Simplex (Cold Sores, Fever Blisters) 218
Description 218
Primary Infection 218
Recurrent Infection 218
Laboratory 219
Differential Diagnosis 219
Course and Prognosis 219
Discussion 219
Treatment 219
Topical Agents 220
Oral Antiviral Agents 221
Pearls 222
Varicella (Chicken Pox) 226
Description 226
History 226
Skin Findings 226
Nonskin Findings 226
Laboratory 226
Complications 227
Differential Diagnosis 227
Treatment 227
Immunocompetent Patients 228
Immunocompromised Patients 228
Pearls 229
Varicella Zoster 231
Description 231
History 231
Skin Findings 231
Ophthalmic Zoster 232
Postherpetic Neuralgia 233
Laboratory 233
Treatment 233
Suppression of Inflammation, Pain, and Infection 233
Attenuation of the Acute Phase 233
Postherpetic Neuralgia 234
Prevention 234
Treatment 234
Varicella Vaccine 234
Pearls 235
Hand-Foot-and-Mouth Disease 236
Description 236
History 236
Skin Findings 236
Course 237
Laboratory 237
Differential Diagnosis 238
Treatment 238
Pearls 238
Zika Virus 240
Description 240
History 240
Skin Findings 240
Laboratory 240
Treatment 240
Pearls 240
9 Fungal Infections 241
Candidiasis (Moniliasis) 241
Description 241
Candida Balanitis 242
Description 242
History 242
Skin Findings 242
Laboratory 242
Differential Diagnosis 242
Course and Prognosis 243
Treatment 243
Pearls 243
Candida Diaper Dermatitis 244
Description 244
History 244
Skin Findings 244
Laboratory 244
Differential Diagnosis 245
Treatment 245
Pearls 245
Candidiasis of Large Skinfolds (Candida Intertrigo) 246
Description 246
History 246
Skin Findings 246
Laboratory 246
Course and Prognosis 246
Differential Diagnosis 246
Treatment 246
Pearls 246
Tinea Versicolor 250
Description 250
History 250
Skin Findings 250
Nonskin Findings 250
Laboratory 250
Differential Diagnosis 250
Course and Prognosis 250
Treatment 250
Pearls 251
Malassezia Folliculitis 253
Description 253
History 253
Skin Findings 253
Laboratory 253
Differential Diagnosis 253
Course and Prognosis 253
Treatment 253
Pearls 253
Tinea of the Nails (Onychomycosis) 255
Description 255
History 255
Skin Findings 255
Distal Subungual Onychomycosis 255
White Superficial Onychomycosis 255
Proximal Subungual Onychomycosis 255
Candida Onychomycosis 255
Laboratory 255
Differential Diagnosis 255
Course and Prognosis 256
Treatment 256
Pearls 256
Angular Cheilitis (Perlèche) 258
Description 258
History 258
Skin Findings 258
Laboratory 258
Differential Diagnosis 258
Course and Prognosis 258
Treatment 258
Pearls 259
Cutaneous Fungal Infections 260
Description 260
History 260
Skin Findings 260
Laboratory 260
Differential Diagnosis 260
Treatment 260
Pearls 265
10 Exanthems and Drug Reactions 282
Nonspecific Viral Rash 282
Description 282
History 282
Skin Findings 282
Nonskin Findings 282
Laboratory and Biopsy 282
Differential Diagnosis 283
Course and Prognosis 283
Roseola Infantum 285
Description 285
History 285
Skin Findings 285
Nonskin Findings 285
Laboratory and Biopsy 285
Differential Diagnosis 285
Course and Prognosis 285
Treatment 285
Pearls 285
Erythema Infectiosum (Fifth Disease) 287
Description 287
History 287
Skin Findings 287
Nonskin Findings 287
Adults 287
Children 287
Pregnancy 287
Laboratory and Biopsy 288
Differential Diagnosis 288
Course and Prognosis 289
Treatment 289
Kawasaki Disease 290
Description 290
Centers for Disease Control and Prevention Diagnostic Criteria for Kawasaki Disease 290
Skin Findings 290
Conjunctival Injection 290
Changes in the Oral Mucous Membranes 290
Changes in the Extremities 290
Rash 290
Nonskin Findings 290
Fever 290
Cervical Lymphadenopathy 291
Cardiac Involvement 291
Laboratory 291
Course and Prognosis 292
Treatment 292
Cutaneous Drug Reactions 294
Description 294
History 294
Morbilliform Eruptions 294
Urticarial Drug Reactions 294
Internal–External Reactions 294
Erythema Multiforme and Toxic Epidermal Necrolysis Reactions 295
Exfoliative Erythroderma 295
Fixed Drug Eruptions 295
Drug-Induced Hyperpigmentation 298
Lichenoid Drug Reactions 298
Photosensitivity Drug Eruptions 298
Onycholysis 299
Small Vessel Necrotizing Vasculitis (Palpable Purpura) 299
Chemotherapy-Induced Acral Erythema 299
Acute Generalized Exanthematous Pustulosis 300
Toxic Shock Syndrome 302
Description 302
History 302
Skin Findings 302
Nonskin Findings 302
Laboratory and Biopsy 302
Differential Diagnosis 302
Course and Prognosis 302
Treatment 302
11 Hypersensitivity Syndromes and Vasculitis 306
Erythema Multiforme 306
Description 306
History 306
Skin Findings 306
Nonskin Findings 307
Laboratory and Biopsy 307
Course and Prognosis 307
Treatment 309
Stevens−Johnson Syndrome and Toxic Epidermal Necrolysis 310
Description 310
History 310
Skin Findings 310
Nonskin Findings 310
Laboratory and Biopsy 310
Differential Diagnosis 310
Course and Prognosis 310
Treatment 311
Erythema Nodosum 313
Description 313
History 313
Skin Findings 313
Nonskin Findings 314
Laboratory and Biopsy 314
Differential Diagnosis 314
Course and Prognosis 314
Treatment 314
Cutaneous Small Vessel Vasculitis (Hypersensitivity Vasculitis) 315
Description 315
History 315
Skin Findings 315
Nonskin Findings 316
Laboratory and Biopsy 316
Differential Diagnosis 316
Course and Prognosis 316
Treatment 316
Immunoglobulin a Vasculitis (Henoch–Schönlein Purpura) 319
Description 319
History 319
Skin Findings 319
Nonskin Findings 319
Laboratory and Biopsy 319
Differential Diagnosis 320
Course and Prognosis 320
Treatment 320
Schamberg’s Disease (Schamberg’s Purpura) 322
Description 322
History 322
Skin Findings 322
Nonskin Findings 322
Laboratory and Biopsy 322
Differential Diagnosis 322
Course and Prognosis 322
Treatment 322
Sweet’s Syndrome 324
Description 324
History 324
Skin Findings 324
Nonskin Findings 324
Laboratory and Biopsy 324
Differential Diagnosis 324
Course and Prognosis 324
Treatment 325
Panniculitis 327
Description 327
History 327
Skin Findings 327
Nonskin Findings 327
Laboratory and Biopsy 327
Differential Diagnosis 327
Course and Prognosis 327
Treatment 327
12 Infestations and Bites 329
Scabies 329
Description 329
History 329
Skin Findings 329
Laboratory and Testing 329
Differential Diagnosis 329
Treatment 330
Pearls 331
Lice (Pediculosis) 334
Description 334
Head Lice 334
History 334
Skin Findings 334
Differential Diagnosis 335
Treatment 335
Standard Topical 335
Alternative Therapies or “Home Remedies” 336
Oral Treatments 336
Nit Removal 336
Botfly Myiasis 337
Description 337
History 337
Skin Findings 337
Laboratory 337
Differential Diagnosis 337
Treatment 337
Pearls 338
Bee and Wasp Stings 339
Description 339
History 339
Skin Findings 339
Differential Diagnosis 339
Treatment 339
Black Widow Spider Bite 341
Description 341
History 341
Skin Findings 341
Differential Diagnosis 341
Treatment 341
Pearls 341
Brown Recluse Spider Bite 343
Description 343
History 343
Skin Findings 343
Laboratory and Pathology 343
Differential Diagnosis 344
Treatment 344
Pearls 344
Lyme Disease 345
Description 345
History 345
Skin Findings 345
Laboratory 345
Differential Diagnosis 345
Treatment 345
Rocky Mountain Spotted Fever 348
Description 348
History 348
Skin Findings 348
Nonskin Findings 348
Course and Prognosis 348
Laboratory 348
Differential Diagnosis 349
Treatment 349
Pearls 349
Flea Bites 350
13 Vesicular and Bullous Diseases 361
Dermatitis Herpetiformis 361
Description 361
History 361
Skin Findings 361
Nonskin Findings 361
Laboratory 361
Course and Prognosis 361
Differential Diagnosis 363
Treatment 363
Pearls 363
Pemphigus Vulgaris 365
Description 365
History 365
Skin Findings 365
Laboratory 365
Course and Prognosis 365
Differential Diagnosis 365
Treatment 366
Pearls 366
Pemphigus Foliaceus 368
Description 368
History 368
Skin Findings 368
Nonskin Findings 368
Laboratory 368
Differential Diagnosis 368
Course and Prognosis 368
Treatment 368
Pearls 368
Bullous Pemphigoid 369
Description 369
History 369
Skin Findings 369
Nonskin Findings 369
Laboratory 369
Differential Diagnosis 369
Course and Prognosis 369
Treatment 369
Pearls 370
14 Connective Tissue Diseases 372
Lupus Erythematosus 372
General Description 372
Treatment Overview 372
Chronic Cutaneous Lupus Erythematosus 375
Description 375
History 375
Laboratory 375
Skin Findings 375
Treatment 375
Subacute Cutaneous Lupus Erythematosus 378
Description 378
History 378
Skin Findings 378
Laboratory 378
Differential Diagnosis 378
Discussion 378
Neonatal Lupus 380
Acute Cutaneous Lupus Erythematosus 381
Description 381
History 381
Skin Findings 381
Differential Diagnosis 381
Laboratory 381
Treatment 381
Pearls 381
Dermatomyositis 383
Description 383
History 383
Skin Findings 383
Nonskin Findings 383
Laboratory 384
Complications 385
Course and Prognosis 385
Differential Diagnosis 386
Treatment 386
Pearls 387
Scleroderma 388
Description 388
History 388
Skin Findings 388
Nonskin Findings 388
Laboratory 388
Differential Diagnosis 389
Complications 389
Course and Prognosis 389
Treatment 389
Pearls 391
Morphea 392
Description 392
History 392
Skin Findings 392
Laboratory 392
Differential Diagnosis 392
Course and Prognosis 392
Treatment 392
Pearls 393
15 Light-Related Diseases and Disorders of Pigmentation 395
Sun-Damaged Skin, Actinic-Damaged Skin, and Photoaging 395
Description 395
History 395
Skin Findings 395
Laboratory 395
Differential Diagnosis 395
Course and Prognosis 395
Treatment 395
Pearls 396
Polymorphous Light Eruption 399
Description 399
History 399
Skin Findings 399
Laboratory 399
Differential Diagnosis 399
Course and Prognosis 399
Discussion 399
Treatment 399
Pearls 400
Porphyria Cutanea Tarda 402
Description 402
History 402
Skin Findings 402
Nonskin Findings 402
Laboratory 402
Differential Diagnosis 402
Course and Prognosis 402
Treatment 402
Vitiligo 405
Description 405
History 405
Skin Findings 405
Nonskin Findings 405
Laboratory 405
Differential Diagnosis 405
Course and Prognosis 405
Treatment 405
Pearls 406
Idiopathic Guttate Hypomelanosis 409
Description 409
History 409
Skin Findings 409
Laboratory 409
Differential Diagnosis 409
Course and Prognosis 409
Treatment 409
Pearls 409
Lentigo (Plural Lentigines), Juvenile Lentigo, Solar Lentigo 411
Description 411
History 411
Freckles 411
Juvenile Lentigines 411
Solar Lentigines 411
Skin Findings 411
Nonskin Findings 411
Laboratory 411
Differential Diagnosis 413
Course and Prognosis 413
Treatment 413
Pearls 413
Melasma (Chloasma, Mask of Pregnancy) 415
Description 415
History 415
Skin Findings 415
Differential Diagnosis 415
Course and Prognosis 415
Treatment 415
Pearls 415
16 Benign Skin Tumors 417
Seborrheic Keratosis 417
Description 417
History 417
Skin Findings 417
Nonskin Findings 418
Laboratory and Testing 418
Course and Prognosis 418
Discussion 418
Treatment 418
Pearls 418
Skin Tags 427
Description 427
History 427
Skin Findings 427
Nonskin Findings 427
Laboratory 427
Course and Prognosis 427
Differential Diagnosis 427
Treatment 427
Pearls 428
Dermatofibroma 429
Description 429
History 429
Skin Findings 429
Laboratory 429
Course and Prognosis 429
Discussion 429
Treatment 430
Pearls 431
Keloids and Hypertrophic Scars 432
Description 432
History 432
Skin Findings 432
Hypertrophic Scars 432
Keloids 432
Laboratory 432
Course and Prognosis 432
Differential Diagnosis 433
Discussion 433
Treatment 433
Pearls 434
Keratoacanthoma 435
Description 435
History 435
Skin Findings 435
Nonskin Findings 435
Laboratory and Pathology 435
Course and Prognosis 435
Discussion 436
Treatment 436
Pearls 436
Nevus Sebaceus 439
Description 439
History 439
Skin Findings 439
Nonskin Findings 439
Laboratory and Testing 439
Course and Prognosis 440
Differential Diagnosis 440
Treatment 440
Pearls 440
Chondrodermatitis Nodularis Helicis 442
Description 442
History 442
Skin Findings 442
Laboratory and Testing 442
Course and Prognosis 442
Differential Diagnosis 443
Discussion 443
Treatment 443
Pearls 443
Epidermal Cyst 444
Description 444
History 444
Skin Findings 444
Nonskin Findings 444
Laboratory 444
Course and Prognosis 444
Treatment 444
Pearls 445
Pilar Cyst 448
Description 448
History 448
Skin Findings 448
Laboratory and Testing 448
Discussion 448
Treatment 448
Pearls 449
Sebaceous Hyperplasia 450
Description 450
History 450
Skin Findings 450
Laboratory 451
Discussion 451
Treatment 451
Pearls 451
Syringoma 452
Description 452
History 452
Skin Findings 452
Laboratory and Pathology 452
Course and Prognosis 452
Differential Diagnosis 452
Discussion 452
Treatment 453
Pearls 453
17 Premalignant and Malignant Nonmelanoma Skin Tumors 454
Basal Cell Carcinoma 454
Description 454
History 454
Skin Findings 454
Nodular Basal Cell Carcinoma 454
Pigmented Basal Cell Carcinoma 456
Superficial Basal Cell Carcinoma 456
Micronodular Basal Cell Carcinoma 456
Morpheaform and Sclerosing Basal Cell Carcinomas 458
Advanced Basal Cell Carcinoma 458
Basal Cell Nevus Syndrome (Gorlin’s Syndrome) 460
Laboratory and Testing 460
Course and Prognosis 460
Discussion 460
Treatment 460
Cryotherapy 460
Curettage 460
Electrosurgery 461
Excision 461
Mohs’ Micrographic Surgery 461
Radiation Therapy 461
Nonsurgical Topical Chemotherapy and Immunotherapy 461
Photodynamic Therapy 462
Pearls 462
Actinic Keratosis 463
Description 463
History 463
Actinic Cheilitis 463
Laboratory and Testing 464
Course and Prognosis 465
Discussion 465
Treatment 465
Actinic Cheilitis Treatment 468
Pearls 468
Squamous Cell Carcinoma 470
Description 470
History 470
Skin Findings 470
Variants of Squamous Cell Carcinoma 471
Nonskin Findings 472
Laboratory and Testing 472
Course and Prognosis 473
Complications 473
Treatment 473
Bowen’s Disease 475
Description 475
History 475
Skin Findings 475
Nonskin Findings 475
Laboratory and Testing 475
Course and Prognosis 476
Differential Diagnosis 476
Clinical 476
Histologic 476
Discussion 476
Treatment 477
Pearls 478
Leukoplakia 479
Description 479
History 479
Skin Findings 479
Laboratory and Testing 479
Course and Prognosis 479
Differential Diagnosis 479
Discussion 480
Treatment 480
Pearls 480
Cutaneous T-Cell Lymphoma 481
Description 481
History 481
Skin Findings 481
Nonskin Findings 481
Laboratory and Testing 482
Differential Diagnosis 482
Treatment 483
Course and Prognosis 483
Pearls 484
Paget’s Disease of the Breast 485
Description 485
History 485
Skin Findings 485
Nonskin Findings 485
Laboratory and Testing 485
Course and Prognosis 485
Differential Diagnosis 485
Discussion 486
Treatment 486
Pearls 486
Extramammary Paget’s Disease 487
Description 487
History 487
Skin Findings 487
Nonskin Findings 487
Laboratory and Testing 487
Course and Prognosis 487
Differential Diagnosis 488
Clinical 488
Histologic 488
Treatment 488
Cutaneous Metastasis 490
Description 490
History 490
Skin Findings 490
Breast Cancer 491
Colon and Rectal Carcinoma 491
Melanoma 491
Lung Carcinoma 491
Renal Cell Carcinoma 492
Oral Squamous Cell Carcinoma 492
Neuroblastoma 492
Lymphomas 492
Leukemia Cutis 492
Nonskin Findings 493
Laboratory 493
Course and Prognosis 493
Discussion 493
Treatment 493
Pearls 493
18 Benign Melanocytic Neoplasms and Melanoma 495
Acquired Melanocytic Nevi (Moles) 495
Description 495
History 495
Skin Findings 495
Junctional Nevi 495
Compound Nevi 495
Intradermal Nevi 495
Nevus Spilus 495
Blue Nevi 495
Spitz Nevus (Spindle and Epithelial Cell Nevus) 497
Halo Nevi 497
Recurrent Nevi 497
Laboratory 497
Course and Prognosis 498
Differential Diagnosis 498
Treatment 498
Pearls 498
Atypical Melanocytic Nevus (Dysplastic Nevus) 500
Description 500
History 500
Skin Findings 502
Nonskin Findings 502
Laboratory 502
Differential Diagnosis 502
Course and Prognosis 502
Treatment 506
Pearls 506
Melanoma 507
Description 507
History 507
Skin Findings 507
Major Subtypes of Melanoma 507
Superficial Spreading Melanoma 507
Nodular Melanoma 507
Lentigo Maligna Melanoma 507
19 Vascular Tumors and Malformations 521
Infantile Hemangiomas 521
Description 521
History 521
Skin Findings 521
Nonskin Findings 521
Laboratory and Pathology 522
Differential Diagnosis 523
Course and Prognosis 523
Treatment 523
When to Refer 524
Pearls 524
Vascular Malformations 526
Description 526
History 526
Skin Findings 526
Capillary Malformations (Slow Flow) 526
Venous Malformations (Slow Flow) 526
Lymphatic Malformation (Slow Flow) 526
Arterial Malformations (Fast Flow) 527
Nonskin Findings 527
Laboratory and Pathology 527
Differential Diagnosis 527
Course and Prognosis 527
Treatment 528
When to Refer 528
Cherry Angioma 529
Description 529
History 529
Skin Findings 529
Nonskin Findings 529
Laboratory and Pathology 529
Differential Diagnosis 529
Course and Prognosis 529
Treatment 529
Pearls 529
Angiokeratoma 531
Description 531
History 531
Angiokeratoma of Fordyce (Most Common) 531
Solitary or Papular Angiokeratomas 531
Angiokeratoma of Mibelli 531
Angiokeratoma Corporis Diffusum 531
Skin Findings 531
Nonskin Findings 531
Laboratory and Pathology 533
Differential Diagnosis 533
Course and Prognosis 533
Treatment 533
When to Refer 533
Pearls 533
Venous Lake 535
Description 535
History 535
Skin Findings 535
Laboratory and Biopsy 535
Differential Diagnosis 535
Course and Prognosis 535
Treatment 535
When to Refer 535
Pearls 535
Pyogenic Granuloma 536
Description 536
History 536
Skin Findings 536
Laboratory and Pathology 536
Differential Diagnosis 536
Course and Prognosis 536
Treatment 538
When to Refer 538
Pearls 538
Kaposi’s Sarcoma 539
Description 539
History 539
Skin Findings 539
Nonskin Findings 539
Laboratory and Biopsy 539
Differential Diagnosis 540
Treatment 540
Classic Kaposi’s Sarcoma 540
Endemic Kaposi’s Sarcoma 540
Immunosuppression-Associated Kaposi’s Sarcoma 540
AIDS-Associated Kaposi’s Sarcoma 540
Pearls 540
Telangiectasias 541
Description 541
History 541
Primary Telangiectasias 541
Hereditary Hemorrhagic Telangiectasia (Osler–Rendu–Weber Disease) 541
Hereditary Benign Telangiectasia 541
Ataxia Telangiectasia (Louis–Bar Syndrome) 541
Generalized Essential Telangiectasia 541
Unilateral Nevoid Telangiectasia 541
Secondary Telangiectasias 541
Skin Findings 543
Nonskin Findings 543
Laboratory and Pathology 544
Differential Diagnosis 545
Discussion 545
Treatment 545
Pearls 545
Spider Angioma (Nevus Araneus) 546
Description 546
History 546
Skin Findings 546
Nonskin Findings 546
Laboratory and Biopsy 546
Differential Diagnosis 546
Course and Prognosis 546
Treatment 546
Pearls 547
20 Hair and Nail Diseases 548
Androgenic Alopecia (Male Pattern Baldness) 548
Description 548
History 548
Skin Findings 548
Course and Prognosis 548
Treatment 548
Pearls 549
Androgenetic Alopecia in Women (Female Pattern Hair Loss) 551
Description 551
History 551
Skin Findings 551
Laboratory 551
Treatment 552
Pearls 552
Telogen Effluvium 554
Description 554
History 554
Skin Findings 554
Nonskin Findings 554
Laboratory 554
Course and Prognosis 555
Differential Diagnosis 555
Treatment 555
Pearls 555
Hair Facts and Hair Cycle Dynamics 555
Scalp Biopsy Mechanics 556
Alopecia Areata 557
Description 557
History 557
Skin Findings 557
Nonskin Findings 557
Laboratory 557
Differential Diagnosis 558
Treatment 558
Pearls 558
Trichotillomania 561
Description 561
History 561
Skin Findings 561
Laboratory 561
Differential Diagnosis 561
Treatment 561
Pearls 562
Nail Diseases 563
Anatomy 563
Growth Rates 563
Nail Biopsy 563
Ridging and Beading 563
Onycholysis 564
Habit-Tic Deformity 565
Psoriasis 565
Acute Paronychia 567
Chronic Paronychia 568
Pseudomonas Species Infection 569
Hangnail 570
Ingrown Toenail 570
Subungual Hematoma 571
Nail Hypertrophy 572
White Spots or Bands 573
Distal Plate Splitting (Onychoschizia) 574
Beau’s Lines 574
Digital Mucous Cysts 574
Nevi and Melanoma 576
Fungal Nail Infections 578
Description 578
History 578
Skin Findings 578
Etiology 579
Laboratory 579
Differential Diagnosis 580
Treatment 580
21 Neonatal Disease 582
Erythema Toxicum Neonatorum 582
Description 582
History 582
Skin Findings 582
Nonskin Findings 582
Laboratory and Biopsy 582
Differential Diagnosis 582
Course and Prognosis 582
Treatment 582
Cutis Marmorata 583
Description 583
History 583
Skin Findings 583
Laboratory and Biopsy 583
Differential Diagnosis 583
Treatment 583
Miliaria 584
Description 584
History 584
Skin Findings 584
Nonskin Findings 584
Laboratory and Biopsy 584
Differential Diagnosis 584
Course and Prognosis 584
Treatment 584
22 Cutaneous Manifestations of Internal Disease 586
Acquired Cutaneous Paraneoplastic Syndromes 586
Description 586
Pruritus 587
History 587
Skin Findings 587
Laboratory and Testing 587
Course and Prognosis 587
Differential Diagnosis 587
Treatment 587
Dermatomyositis 588
History 588
Skin Findings 588
Nonskin Findings 588
Laboratory and Testing 588
Course and Prognosis 589
Differential Diagnosis 589
Treatment 589
Sweet’s Syndrome 590
History 590
Skin Findings 590
Nonskin Findings 590
Laboratory and Testing 590
Course and Prognosis 590
Differential Diagnosis 590
Treatment 590
Carcinoid Syndrome 592
History 592
Skin Findings 592
Nonskin Findings 592
Laboratory and Tests 592
Course and Prognosis 592
Differential Diagnosis 592
Treatment 592
Glucagonoma Syndrome 593
History 593
Skin Findings 593
Nonskin Findings 593
Laboratory and Testing 593
Course and Prognosis 593
Differential Diagnosis 593
Treatment 593
Paraneoplastic Pemphigus 594
History 594
Skin Findings 594
Nonskin Findings 594
Laboratory 594
Course and Prognosis 594
Differential Diagnosis 594
Sign of Leser–Trélat 595
History 595
Skin Findings 595
Laboratory and Testing 595
Course and Prognosis 595
Differential Diagnosis 595
Treatment 595
Pearls 595
Inherited Cutaneous Paraneoplastic Syndromes 596
Description 596
History 596
Cowden’s Syndrome 597
Description 597
Skin Findings 597
Nonskin Findings 597
Laboratory and Testing 597
Course and Prognosis 597
Treatment 597
Gardner’s Syndrome 598
Description 598
Skin Findings 598
Nonskin Findings 598
Laboratory and Testing 598
Course and Prognosis 598
Treatment 598
Muir–Torre Syndrome 599
Description 599
Skin Findings 599
Nonskin Findings 599
Laboratory and Testing 599
Course and Prognosis 599
Treatment 599
Discussion 599
Pearls 599
Acanthosis Nigricans 601
Description 601
History 601
Skin Findings 601
Nonskin Findings 601
Laboratory and Testing 601
Discussion 601
Treatment 601
Pearls 602
Neurofibromatosis 603
Description 603
History 603
Skin Findings 603
Nonskin Findings 603
Laboratory and Testing 603
Course and Prognosis 603
Discussion 604
Treatment 605
Pearls 605
Tuberous Sclerosis 607
Description 607
History 607
Skin Findings 607
Nonskin Findings 607
Central Nervous System 607
Renal System 607
Cardiac System 607
Pulmonary System 607
Other Organ Systems 608
Laboratory and Testing 608
Course and Prognosis 608
Differential Diagnosis 608
Treatment 609
Granuloma Annulare 611
Description 611
History 611
Skin Findings 611
Nonskin Findings 611
Laboratory and Testing 611
Differential Diagnosis 611
Treatment 613
Pearls 613
Necrobiosis Lipoidica 614
Description 614
History 614
Skin Findings 614
Nonskin Findings 614
Laboratory and Testing 614
Course and Prognosis 614
Treatment 614
Pearls 615
Pyoderma Gangrenosum 617
Description 617
History 617
Skin Findings 617
Nonskin Findings 617
Laboratory and Testing 618
Differential Diagnosis 618
Treatment 618
Systemic Therapy 618
Topical Therapy 619
Course and Prognosis 619
23 Lasers in Dermatology 621
Introduction 621
Uses of Lasers in Dermatology 621
Pigmentation 621
Blood Vessels 621
Hair Removal 621
Tattoo Removal 621
Wrinkles and Rhytids (Skin Tightening) 622
Destruction and Ablation 622
Wavelengths 622
Complications and Limitations 623
24 Leishmaniasis 624
Description 624
History 624
Skin Findings 625
Cutaneous Leishmaniasis 625
Mucocutaneous Leishmaniasis 625
Diffuse Cutaneous Leishmaniasis 627
Nonskin Findings 627
Visceral Leishmaniasis (Kala Azar) 627
Laboratory 627
Course and Prognosis 627
Differential Diagnosis 628
Treatment 628
Pearl 629
25 Leprosy (Hansen’s Disease) 630
Description 630
History 630
Skin Findings 631
Lepromatous Leprosy 632
Borderline Leprosy 632
Tuberculoid Leprosy 632
Nonskin Findings 632
Laboratory and Testing 633
Course and Prognosis 633
Differential Diagnosis 633
Treatment 633
Discussion 633
A Quick Reference Formulary 635
Dietary Recommendations 644
Do Eat… 644
Do Limit… 644
Index 645
A 645
B 647
C 649
D 651
E 653
F 654
G 655
H 656
I 658
J 659
K 659
L 660
M 661
N 663
O 664
P 665
Q 668
R 668
S 669
T 671
U 673
V 673
W 674
X 674
Y 674
Z 674
Corticosteroids (Topical) 680