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Interatrial Block and Supraventricular Arrhythmias: Clinical Implications of Bayés’ Syndrome

Interatrial Block and Supraventricular Arrhythmias: Clinical Implications of Bayés’ Syndrome

Adrian Baranchuk

(2017)

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Book Details

Abstract

Bayés’ syndrome refers to the association between interatrial block and supraventricular arrhythmias—mainly the occurrence of atrial fibrillation. It is also a risk factor for cardio-embolic stroke. Rapid recognition by analyzing characteristic patterns in the surface ECG will help the physician to closely monitor the patient for atrial fibrillation and decide on anticoagulation therapy if the clinical risk of stroke is increased. Interatrial blocks were described several decades ago; however, they are now gaining the attention of the medical community as a means of helping to identify patients at high risk of developing atrial fibrillation and/or cardio-embolic stroke. I welcome all readers to navigate this book and to become familiar with this concept that is helping to renovate our models of predicting atrial fibrillation and stroke.
Interatrial Block and Supraventricular Arrhythmias: Clinical Implications of Bayés’ Syndrome, has been superbly edited by Adrian Baranchuk, an important clinical investigator of the syndrome. Baranchuk has thoughtfully and successfully pulled together the many threads of clinical research on the syndrome. This book will surely stimulate interest in what has been a largely neglected corner of cardiology. As a consequence of the outstanding work of Bayés, Baranchuk, and the authors who have contributed to this book, interatrial block is no longer a stepchild. -Eugene Braunwald, MD Boston, Massachusetts

Table of Contents

Section Title Page Action Price
Cover i
Title Page v
Copyright vi
Contents vii
About the Authors ix
Foreword xiii
Preface xvii
Chapter 1: The Long Journey to the Diagnosis of Interatrial Blocks: ECG-VCG Criteria 1
Introduction 1
Where Are the Interatrial Blocks Anatomically Located? 3
When Should an ECG Pattern Be Considered a Block? 5
How to Diagnose Interatrial Blocks 5
How to Measure the Duration of the P-Wave (ECG) and the P Loops (VCG)? 6
The ECG-VCG Diagnostic Criteria 9
Clinical Implications 14
Conclusions 15
References 15
Chapter 2: Normal Atrial Electrical Activity 17
Introduction 17
Normal P-Wave: Where Does It Come From? 18
Interatrial Routes: Anatomy and Function 19
Variability of Sinus Rhythm Origin and P-Wave Morphology 22
Atrial Geometry and Size as Determinants of P-Wave Morphology in Healthy Men 23
References 24
Chapter 3: Structure of the Bachmann’s Bundle 27
Introduction 27
Gross Anatomy of the Atria 28
Normal Atrial Myoarchitecture 30
The Gross Structure of the Bachmann’s Bundle and Its Extensions 32
Structural Myoarchitecture of the Bachmann’s Bundle 38
Bachmann’s Bundle and Its Vascularization 40
Conclusion 41
References 41
Chapter 4: Pathophysiology of the Interatrial Blocks 43
Introduction 43
Electrophysiological, Ultrastructural, and Anatomic Atrial Remodeling 44
How to Detect Atrial Fibrosis: From New Imaging Techniques to Old ECG Recordings 46
The Value of ECG/VCG in Understanding the Pathophysiology of IAB 48
Conclusions 49
References 49
Chapter 5: Contributions of Noncontact Mapping to the Understanding of Normal Atrial Activation 51
Introduction 51
Interatrial Activation 51
Clinical Significance of Advanced Interatrial Block (IAB) 55
Role of Advanced IAB as Risk Predictor of Atrial Fibrillation 57
Conclusion 58
References 58
Chapter 6: Contributions of Noncontact and Contact Mapping to the Understanding of Interatrial Block 61
Introduction 61
Noncontact Mapping to Record Interatrial Conduction During Sinus Rhythm and Atrial Pacing 62
Activation Mapping of Interatrial Block in Sinus Rhythm and Atrial Arrhythmias 63
Future Considerations 64
References 65
Chapter 7: Epidemiology of Interatrial Block 67
Introduction 67
Prevalence 67
Pathophysiology 69
Clinical Implications and Associated Conditions 71
Therapeutic Approaches 75
Conclusion 76
References 77
Chapter 8: Consensus Document on Interatrial Blocks: 2016 Update 79
Introduction 79
Classification of Blocks at the Atrial Level 80
Rules for IAB to Be Considered a Specific ECG Pattern 80
The ECG-VCG Diagnostic Criteria of Advanced IAB (A-IAB) 81
Unanswered Questions: The Challenges Ahead 84
Conclusions 85
References 85
Chapter 9: Interatrial Block and Supraventricular Arrhythmias: Bayés’ Syndrome 89
Introduction 89
Identification of the Syndrome 90
Importance of Contributing to Predict AF Integrating the ECG Within the Risk Model 92
Brief Summary on the Importance of Detecting AF 93
References 94
Chapter 10: Correlation of Interatrial Block with Left Atrial Enlargement and P-Wave Terminal Force 97
Introduction and Definitions 97
Correlation of Interatrial Block with P-Wave Terminal Force 98
Correlation of IAB with Left Atrial Enlargement 103
Summary 104
References 104
Chapter 11: Interatrial Block and Stroke 107
Introduction 107
Methods 107
Definition of IAB 108
Etiopathogenesis 108
Data and Discussion 109
Therapeutic Interventions for IAB 112
Conclusion 112
References 113
Chapter 12: Interatrial Block as a Predictor of Atrial Fibrillation 117
Introduction 117
Pathophysiological Considerations 118
General Population 119
Post Catheter Ablation of Atrial Fibrillation and Flutter 119
Post Cardioversion of Atrial Fibrillation 121
Cardiomyopathies 121
After Cardiac Surgery 122
Conclusion 123
References 123
Chapter 13: Interatrial Block as a Predictor of Post-CABG Atrial Fibrillation 125
Introduction 125
Atrial Fibrillation Following Cardiac Surgery 126
Interatrial Block Is Not a Predictor of Post-CABG Atrial Fibrillation 126
P-Wave Morphology and PCAF 127
Conclusion 128
References 128
Chapter 14: Interatrial Block in Octogenarians and Up 129
Introduction 129
References 134
Chapter 15: Interatrial Block in Hemodialysis Patients 137
Introduction 137
Recent Insight on Uremic Cardiomyopathy 138
IAB as a Sign of Uremic Cardiomyopathy 138
Literature Review 139
Prevalence of IAB in Hemodialysis Patients 139
Pathophysiology of IAB in Hemodialysis Patients 139
Clinical Implications of IAB in the Hemodialysis Population 140
Advanced IAB (and Bayés’ Syndrome) in Hemodialysis Population 140
Renal Replacement Therapies and P-Wave Changes 142
Conclusions 142
References 142
Chapter 16: Interatrial Block in Severe Heart Failure and the Impact of Cardiac Resynchronization Therapy 145
Introduction 145
Congestive Heart Failure and Atrial Fibrillation: Cause and Effect 145
Predicting Atrial Fibrillation in Heart Failure: Role of Advanced Interatrial Block 147
Reverse Structural Remodeling of the Left Ventricle and Left Atrium: Role of Cardiac Resynchronization Therapy 149
Conclusion 151
References 151
Chapter 17: Interatrial Block in Patients with Sleep Apnea and the Impact of CPAP 155
Introduction 155
The Link Between OSA and AF 156
The Prevalence of IAB in Patients with Moderate to Severe OSA 157
Reverse Atrial Electrical Remodeling Induced by CPAP 158
Conclusion 159
References 159
Chapter 18: Progressive Interatrial Block 161
Introduction 161
Pathophysiology of the Atrial Conduction 162
Progressive IAB and Progressive Interatrial Remodeling 164
Reversal of Progressive Atrial Remodeling 166
Post-Atrial Fibrillation Cardioversion 166
Post-Atrial Fibrillation Catheter Ablation 167
Post-Mitral Valve Commissurotomy 167
Post-Cardiac Resynchronization Therapy 167
Post-Continuous Positive Airway Pressure in Obstructive Sleep Apnea 168
Conclusion 168
References 168
Chapter 19: Atrial Resynchronization by Biatrial Pacing: Is This a Solution? 171
Introduction 171
Technical Aspects (Chronic Implants) 172
Antiarrhythmic Properties 174
Hemodynamic Effects 177
Conclusion 179
References 180
Chapter 20: The Future (and Challenge) of Treating Interatrial Block in the 21st Century 183
Introduction 183
Should We Prevent Atrial Arrhythmias in These Patients? 184
Should We Consider Anticoagulation in Patients Without Evidence of Atrial Fibrillation or Atrial Flutter? 186
References 189
Index 191