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Havard's Nursing Guide to Drugs - Mobile optimised site

Havard's Nursing Guide to Drugs - Mobile optimised site

Adriana P. Tiziani

(2017)

Additional Information

Book Details

Abstract

The premier drug guide for nurses and midwives since 1983.

Now in its first digital version, Havard's Nursing Guide to Drugs, 10th edition mobile-optimised site brings over 30 years of knowledge to your fingertips, allowing you to search by body system, therapeutic class or drug name. The same trusted, safe and up-to-date drug information is now accessible online via your mobile or tablet, providing the perfect support to your study or clinical practice.

It continues to deliver administration information regarding form, action, use, dose, adverse effects and interactions in compliance with current pharmaceutical guidelines from the Therapeutic Goods Administration and MIMS. Nursing points and cautions highlight best practice in drug administration and expanded focus on Patient teaching and advice ensures quality patient care.

  • All drugs listed by therapeutic class and by body system
  • Both trade names and generic drug names are provided
  • Icons indicate cautions for drugs used during pregnancy and breastfeeding, and drug specific restrictions in sport
  • Common abbreviations, units and concentrations

Table of Contents

Section Title Page Action Price
Front Cover cover
Inside Front Cover ifc1
Havard's Nursing Guide to Drugs i
Copyright Page iv
Contents by Therapeutic Class v
Contents by Body System vii
Preface ix
Introduction xi
The nurse’s role in drug therapy xi
Assessing the patient xi
Children and the elderly xiii
Drugs in sport xiii
Pregnancy xiv
Breastfeeding xv
Renal and liver impairment xv
Legal requirements xv
Storage xvi
Drug orders xvii
Legal responsibility xviii
Drug incidents (errors) xviii
A little pharmacokinetics xix
Pharmacokinetics and the older person xx
Drug dosage xx
Drug half-life xx
Therapeutic drug monitoring xxi
Why measure drug levels? xxi
Drug route xxi
Oral administration xxi
Parenteral administration xxii
Intramuscular xxii
Subcutaneous xxii
Intravenous xxii
Guide for safe administration xxiv
Check the order xxiv
Check the drug xxiv
Check the patient xxiv
Documentation xxv
Disposal xxv
Drug effects xxv
Summary xxvi
At a glance xxvi
Available forms xxvi
Action xxvi
Use xxvi
Dose xxvi
Adverse effects xxvi
Interactions xxvii
Nursing points/Cautions xxvii
Patient teaching and advice xxvii
General Patient teaching and advice xxviii
Dosage xxx
How to take xxx
Adverse effects xxxi
Storage xxxi
Other issues xxxii
Reviewers xxxiii
Acne treatment 1
Retinoids 2
General Actions of retinoids 2
General Adverse effects of oral retinoids 2
General Interactions of oral retinoids 2
General Nursing points/Cautions for retinoids 2
General Patient teaching and advice for retinoids 3
Topical therapy 3
Oral therapy 4
ACITRETIN (Neotigason, Novatin) 5
Analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) 11
General Actions of NSAIDs (not paracetamol) 11
General Adverse effects of NSAIDs (not paracetamol) 12
General Interactions of NSAIDs (not paracetamol) 12
General Nursing points/Cautions for NSAIDs (not paracetamol) 13
General Patient teaching and advice for NSAIDs 14
Topical gel 14
Eye drops 15
Suppositories 15
ASPIRIN (Aspro preparations, Aspro Clear Extra Strength, Astrix 100, Astrix Tablets, Cardasa, Cardiprin 100, Cartia, Disprin preparations, Solprin, Spren) 16
Available forms 16
Action 16
Use 16
Dose 16
Adverse effects 16
Interactions 16
Nursing points/Cautions 17
Anorectics and weight-loss agents 37
LIRAGUTIDE (Saxenda, Victoza) 37
Available form 37
Action 37
Antacids 41
ALUMINIUM HYDROXIDE HYDRATE (ALUMINIUM HYDROXIDE) (Alu-Tab) 41
Available form 41
Action 41
Use 41
Dose 41
Adverse effects 41
Interactions 41
Nursing points/Cautions 41
Anthelmintics 44
General Patient teaching and advice for helminth infestation 44
ALBENDAZOLE (Eskazole, Zentel) 45
Available forms 45
Action 45
Use 45
Dose 45
Hydatid disease 45
Neurocysticercosis 45
Capillariasis 45
Pinworm, threadworm, roundworm, hookworm, whipworm 45
Strongyloides 45
Cutaneous larva migrans 45
Mixed worm infestation (including liver flukes) 46
Tape worm 46
Adverse effects 46
Interactions 46
Nursing points/Cautions 46
Patient teaching and advice 46
IVERMECTIN (Soolantra, Stromectol) 47
Available forms 47
Action 47
Use 47
Dose 47
Adverse effects 47
Strongyloidiasis 47
Onchocerciasis 47
Scabies 47
Rosacea 47
Nursing points/Cautions 48
Patient teaching and advice 48
Scabies 48
Rosacea 48
MEBENDAZOLE (Combantrin-1 with Mebendazole, Combantrin-1 with Mebendazole Chocolate Squares, DeWorm Chewable Tablets, Ridworm, Vermox) 49
Available forms 49
Anti-Alzheimer’s Agents 52
General Actions of anti-Alzheimer’s agents (anticholinesterases) 52
General Adverse effects of anti-Alzheimer’s agents (anticholinesterases) 52
General Interactions of anti-Alzheimer’s agents (anticholinesterases) 53
General Nursing points/Cautions for anti-Alzheimer’s agents (anticholinesterases) 53
General Patient/Carer teaching and advice for anti-Alzheimer’s agents 53
DONEPEZIL HYDROCHLORIDE (Arazil, Aricept, Aridon, Aridon APN, Donepezil RBX, Donepezil-DRLA, Donepezil-GA) 54
Antianginal agents 58
General Patient teaching and advice for antianginal agents 59
GLYCERYL TRINITRATE (often abbreviated to GTN) (known as nitroglycerin in USA) (Anginine, DBL Glyceryl Trinitrate Concentrate Injection, Lycinate, Minitran, Nitrolingual Pump Spray, Nitro-Dur, Transiderm-Nitro) 59
Available forms 59
Action 59
Use 60
Dose 60
Treatment of acute attack 60
Prophylaxis 60
Adverse effects 60
Interactions 60
Nursing points/Cautions 61
Patient teaching and advice 62
Sublingual tablets 62
Sublingual spray 62
Transdermal patch 63
Note 63
ISOSORBIDE DINITRATE 63
ISOSORBIDE MONONITRATE (Duride, Imdur Durules, Isomonit, Isosorbide AN, Isosorbide PS, Monodur Durules) 63
Available forms 63
Action 63
Use 64
Dose 64
Acute angina 64
Prophylactic treatment of angina pectoris, myocardial ischaemia 64
Acute left ventricular failure 64
Chronic left ventricular failure 64
Adverse effects 64
Interactions 64
Nursing points/Cautions 64
Patient teaching and advice 65
IVABRADINE (Coralan) 65
Available forms 65
Action 65
Use 65
Dose 66
Adverse effects 66
Interactions 66
Nursing points/Cautions 66
Patient teaching and advice 67
NICORANDIL (Ikorel, Ikotab) 67
Available forms 67
Action 67
Use 67
Dose 67
Adverse effects 67
Interactions 67
Nursing points/Cautions 67
Patient teaching and advice 68
PERHEXILINE MALEATE (Pexsig) 68
Available form 68
Action 68
Use 68
Dose 68
Adverse effects 68
Short term (within 24 hours) 68
Long term (≥ 12 weeks of continuous therapy) 68
Interactions 68
Nursing points/Cautions 69
Patient teaching and advice 69
Antianxiety agents 70
General Actions of antianxiety agents 70
General Adverse effects of antianxiety agents 71
General Interactions of antianxiety agents 71
General Nursing points/Cautions for antianxiety agents 71
General Patient teaching and advice for antianxiety agents 72
ALPRAZOLAM (Alprax, Kalma) 73
Available forms 73
Action 73
Use 73
Dose 73
Adverse effects 73
Interactions 73
Nursing points and Cautions/Patient teaching and advice 73
BROMAZEPAM (Lexotan) 74
Available forms 74
Antiarrhythmic agents 78
Class I 78
Class IA 78
DISOPYRAMIDE (Rythmodan) 78
Available forms 78
Action 78
Use 79
Dose 79
Adverse effects 79
Interactions 79
Nursing points/Cautions 79
Patient teaching and advice 80
Class IB 81
LIDOCAINE (LIGNOCAINE) HYDROCHLORIDE (Lidocaine Injection, Min-I-Jet Lidocaine Hydrochloride, Xylocard) 81
Available forms 81
Action 81
Use 81
Dose 81
Adverse effects 81
Interactions 81
Nursing points/Cautions 82
Note 82
Class IC 83
FLECAINIDE ACETATE (Flecatab, Tambocor) 83
Available forms 83
Action 83
Use 83
Dose 83
Adverse effects 83
Interactions 83
Nursing points/Cautions 83
Patient teaching and advice 84
Class II 84
Class III 85
AMIODARONE HYDROCHLORIDE (Aratac, Cardinorm, Cordarone X, Rithmik) 85
Available forms 85
Action 85
Use 85
Dose 85
Adverse effects 85
Interactions 85
Nursing points/Cautions 86
Patient teaching and advice 87
SOTALOL HYDROCHLORIDE (Cardol, Cardol 80 mg, Solavert, Sotacor) 87
Available forms 87
Action 87
Use 87
Dose 87
Adverse effects 88
Interactions 88
Nursing points/Cautions 88
Patient teaching and advice 89
Class IV 89
Atypical Antiarrhythmic Agents 90
ADENOSINE (Adenocor, Adenoscan Adenosine Mylan Injection) 90
Available forms 90
Action 90
Use 90
Dose 90
Adverse effects 90
Interactions 90
Nursing points/Cautions 90
Patient teaching and advice 91
Antiasthma agents, bronchodilators and respiratory agents 92
Symptom relievers (bronchodilators) 93
Symptom controllers (bronchodilators) 93
Symptom preventers (prophylactic and anti-inflammatory drugs) 93
General Patient teaching and advice for antiasthma agents and bronchodilators 93
Spacer device 94
Nebuliser 94
Aerolizer 94
Bronchodilators (Beta-2 Adrenoceptor Agonists (also Called Beta-2 Agonists)) 95
General Adverse effects of beta-2 adrenoceptor agonists 95
Common effects 95
Less common 95
General Interactions of beta-2 adrenoceptor agonists 95
FORMOTEROL (EFORMOTEROL) FUMARATE DIHYDRATE (Foradile, Oxis Turbuhaler) 96
Available forms 96
Action 96
Use 96
Dose 96
Adverse effects 96
Interactions 96
Nursing points/Cautions 96
Patient teaching and advice 97
Note 97
INDACATEROL (Onbrez Breezhaler) 97
Available form 97
Action 97
Use 97
Dose 97
Adverse effects 97
Interactions 97
Nursing points/Cautions 97
Patient teaching and advice 98
Note 98
OLODATEROL (Striverdi Respimat) 98
Available form 98
Action 98
Use 98
Dose 98
Adverse effects 98
Interactions 99
Nursing points/Cautions 99
Patient teaching and advice 99
Note 100
SALBUTAMOL SULFATE (known as albuterol in the USA) (Airomir Autohaler and Inhaler, Asmol CFC-free Inhaler, Asmol Uni Dose, Butamol, Epaq, Salbutamol Inhalation Solution, Ventolin preparations, Ventolin Obstetric Injection) 100
Available forms 100
Action 100
Use 100
Dose 100
Adverse effects 100
Interactions 100
Nursing points/Cautions 101
Patient teaching and advice 101
Metered dose aerosol inhaler 102
Rotahaler 102
Autohaler 103
SALMETEROL XINAFOATE (Serevent) 104
Available form 104
Antibacterial agents 136
General Nursing points/Cautions for antibacterial agents 137
General Patient teaching and advice for antibacterial agents 139
Inhibitors of Bacterial Cell Wall Synthesis 139
Penicillins 140
General Actions of penicillins 140
General Uses of penicillins 140
General Adverse effects of penicillins 140
General Interactions of penicillins 141
General Nursing points/Cautions for penicillins 141
General Patient teaching and advice for penicillins 142
AMOXICILLIN SODIUM 142
AMOXICILLIN TRIHYDRATE (Alphamox, Amoxil Oral, Bgramin, Cilamox, Maxamox, Ranmoxy, Xycilan, Yomax) 142
Available forms 142
Action 143
Use 143
Dose 143
Adverse effects 143
Interactions 143
Nursing points/Cautions 144
Patient teaching and advice 144
Note 144
AMOXICILLIN TRIHYDRATE WITH CLAVULANIC ACID (Augmentin preparations, AlphaClav Duo, AlphaClav Duo Forte, AmoxyClav, Clamoxyl preparations, Clavam, Clavulin preparations, Clavycillin, Curam preparations, GA-Amclav, Moxiclav preparations) 144
Available forms 144
Action 144
Use 144
Dose 144
Adverse effects 145
Interactions 145
Nursing points/Cautions 145
Patient teaching and advice 145
AMPICILLIN SODIUM (Ampicyn, Austrapen, Ibimycin) 145
Available forms 145
Action 145
Use 145
Dose 145
Anticoagulants and antithrombotic agents 216
General Patient teaching and advice for anticoagulants 217
Heparin and Low Molecular Weight Heparins (LMWHs) 217
HEPARIN SODIUM (Heparin Injection BP, Heparin Sodium Injection, Heparinised Saline) 217
Available forms 217
Action 217
Use 218
Dose 218
Adverse effects 218
Interactions 218
Nursing points/Cautions 219
Subcutaneous injection technique 219
General 219
Patient teaching and advice 220
Note 220
Low Molecular Weight Heparins 221
DALTEPARIN SODIUM (Fragmin) 221
Available forms 221
Action 221
Use 221
Dose 221
Acute DVT treatment 221
Treatment of symptomatic VTE in those with solid tumour cancers 221
Anticoagulation for haemodialysis 221
Thromboprophylaxis (surgery) 221
Thromboprophylaxis (general surgery associated with high thrombosis risk) 221
Thromboprophylaxis (orthopaedic surgery e.g. hip replacement) 221
Unstable coronary disease 221
Adverse effects 222
Interactions 222
Nursing points/Cautions 222
Patient teaching and advice 222
DANAPAROID SODIUM (Orgaran) 223
Antidepressants 240
General Nursing points/Cautions for all antidepressants 241
General Patient teaching and advice for all antidepressants 241
Tricyclic and Related Antidepressants (TCAs) 242
General Actions of TCAs 242
General Adverse effects of TCAs 242
General Interactions of TCAs 243
General Nursing points/Cautions for TCAs 244
General Patient teaching and advice for TCAs 244
AMITRIPTYLINE HYDROCHLORIDE (Endep, Entrip) 245
Available forms 245
Action 245
Use 245
Dose 245
Depression 245
Enuresis 245
Antidiabetic agents 267
Insulins 268
Available forms 269
General Actions of insulins 269
General Use of insulins 269
Dose 269
General Adverse effects of insulins 269
General Interactions of insulins 270
General Nursing points/Cautions for insulins 270
Short-acting (soluble) insulin 271
Long-acting (depot) insulin 271
Storage 271
Preparation 271
Administration 272
General Patient teaching and advice for insulins 272
Oral Hypoglycaemic Agents 276
General Nursing points/Cautions for oral hypoglycaemic agents 276
General Patient teaching and advice for oral hypoglycaemic agents 277
Sulfonylureas 278
General Actions of sulfonylureas 278
General Uses of sulfonylureas 278
General Adverse effects of sulfonylureas 278
General Interactions of sulfonylureas 278
General Nursing points/Cautions for sulfonylureas 279
General Patient teaching and advice for sulfonylureas 279
GLIBENCLAMIDE (Daonil, Glimel) 280
Available form 280
Action/Use 280
Dose 280
Interactions 280
Adverse effects/Nursing points/Cautions/Patient teaching and advice 280
Note 280
GLICLAZIDE (Diamicron 60 mg MR, Glyade, Glyade MR, Nidem, Oziclide MR) 280
Available forms 280
Antidiarrhoeal agents 299
General Nursing points/Cautions for antidiarrhoeal agents 300
General Patient teaching and advice for antidiarrhoeal agents 300
DIPHENOXYLATE HYDROCHLORIDE 300
Available forms 300
Action 300
Use 300
Dose 300
Adverse effects 300
Interactions 301
Nursing points/Cautions 301
Patient teaching and advice 301
Note 301
LOPERAMIDE HYDROCHLORIDE (Diacare, Diareze, Gastrex, GastroStop, Harmonise, Imodium, Lopedium, Pharmacy Action Diarrhoea Relief, StopIt) 301
Available forms 301
Action 301
Use 301
Dose 302
Adverse effects 302
Interactions 302
Nursing points/Cautions 302
Patient teaching and advice 302
Antidotes, antagonists and chelating agents 303
ACETYLCYSTEINE (Acetadote Concentrated Injection, DBL Acetylcysteine Injection Concentrate) 303
Available forms 303
Action 303
Use 303
Dose 303
Adverse effects 303
Interactions 303
Nursing points/Cautions 304
BETAINE (Cystadane) 304
Available form 304
Action 304
Antiemetic agents 333
Note 333
5HT3 Receptor Antagonists 334
General Adverse effects of 5HT3 receptor antagonists 334
General Interactions of 5HT3 receptor antagonists 334
General Nursing points/Cautions for 5HT3 receptor antagonists 334
General Patient teaching and advice for 5HT3 receptor antagonists 334
DOLASETRON MESILATE (MESYLATE) MONOHYDRATE (Dolasetron Mesylate) (Anzemet) 334
Available forms 334
Action 334
Use 334
Antiepileptics 347
General Adverse effects of antiepileptics 348
General Nursing points/Cautions for antiepileptics 348
General Patient teaching and advice for antiepileptics 349
ACETAZOLAMIDE (Diamox, Glaumox, Powder for Injection) 350
Available forms 350
Action 350
Antifungal agents 378
AMOROLFINE (Aporyl, Loceryl, Myconail, Sandoz Nail Repair) 378
Available form 378
Action 378
Use 378
Antiglaucoma agents 408
General Actions of antiglaucoma agents 408
General Ocular Adverse effects of antiglaucoma agents 409
General Adverse effects (uncommon) of antiglaucoma agents 409
General Nursing points/Cautions for antiglaucoma agents 409
General Patient teaching and advice for antiglaucoma agents 409
Instillation of eye drops 410
ACETAZOLAMIDE (Diamox, Glaumox Powder for Injection) 410
Available forms 410
Action 410
Antigout and uricolytic agents 422
ALLOPURINOL (Allosig, Progout, Zyloprim) 422
Available forms 422
Action 422
Use 423
Dose 423
Gout 423
High urate turnover conditions 423
High urate turnover conditions (with renal impairment) 423
Adverse effects 423
Interactions 423
Nursing points/Cautions 423
Patient teaching and advice 424
COLCHICINE (Colgout, Lengout) 424
Available form 424
Action 424
Use 424
Dose 424
Adverse effects 424
Interactions 425
Nursing points/Cautions 425
Patient teaching and advice 426
FEBUXOSTAT (Adenuric) 426
Available form 426
Action 426
Use 426
Dose 426
Adverse effects 426
Interactions 426
Nursing points/Cautions 426
Patient teaching and advice 427
PROBENECID (Pro-Cid) 427
Available form 427
Action 427
Use 427
Dose 427
Adverse effects 427
Interactions 428
Nursing points/Cautions 428
Patient teaching and advice 428
RASBURICASE RYS (Fasturtec) 429
Available forms 429
Action 429
Use 429
Dose 429
Adverse effects 429
Nursing points/Cautions 429
Antihistamines 431
General Actions of antihistamines 432
General Adverse effects of antihistamines 432
General Interactions of antihistamines 432
General Nursing points/Cautions for antihistamines 432
General Patient teaching and advice for antihistamines 432
Nasal spray instillation 432
Eye drop instillation 433
ALIMEMAZINE (TRIMEPRAZINE) TARTRATE (Vallergan, Vallergan Syrup Forte) 433
Available forms 433
Action 433
Use 434
Dose 434
Adverse effects 434
Interactions 434
Nursing points/Cautions 434
Antihypertensive agents 446
General Patient teaching and advice for antihypertensive agents 447
Alpha-Adrenoceptor Blocking Agents 447
General Actions of alpha-adrenoceptor blocking agents 447
General Adverse effects of alpha-adrenoceptor blocking agents 447
General Nursing points/Cautions for alpha-adrenoceptor blocking agents 448
General Patient teaching and advice for alpha-adrenoceptor blocking agents 448
PHENOXYBENZAMINE HYDROCHLORIDE (Dibenyline, Dibenzyline) 448
Available form 448
Action 448
Antimalarial agents 495
The malarial life cycle 495
Treatment 496
Prevention 496
General Patient teaching and advice for people travelling in malarial areas 496
Malaria and pregnancy 497
ARTEMETHER AND LUMEFANTRINE (Riamet) 497
Available forms 497
Action 497
Use 497
Dose 497
Adverse effects 498
Interactions 498
Nursing points/Cautions 498
Patient teaching and advice 498
ATOVAQUONE AND PROGUANIL HYDROCHLORIDE (Malarone Tablets (250/100), Malarone Junior Tablets (62.5/25), Promozio 250/100) 499
Available forms 499
Action 499
Use 499
Dose 499
Prophylaxis 499
Treatment 499
Adverse effects 499
Interactions 500
Nursing points/Cautions 500
Patient teaching and advice 500
MEFLOQUINE HYDROCHLORIDE (Lariam) 500
Available form 500
Action 500
Use 500
Dose (adults and children more than 45 kg) 501
Treatment (non-immune person from endemic malarial area) 501
Treatment (semi-immune person living in malaria endemic area) 501
Malaria prophylaxis (for a stay of 1–3 weeks in a malarial area) 501
Adverse effects 501
Interactions 501
Nursing points/Cautions 501
Patient teaching and advice 501
PRIMAQUINE PHOSPHATE (Primacin) 502
Available form 502
Action 502
Use 502
Dose 502
Adverse effects 502
Interactions 502
Nursing points/Cautions 502
Patient teaching and advice 503
QUININE BISULFATE HEPTAHYDRATE (QUININE BISULFATE) 503
QUININE DIHYDROCHLORIDE 503
QUININE SULFATE DIHYDRATE (QUININE SULFATE) (Quinate) 503
Available forms 503
Action 503
Use 503
Dose 503
Adverse effects 503
Interactions 504
Nursing points/Cautions 504
Patient teaching and advice 505
Note 505
Antimigraine agents 506
CYPROHEPTADINE HYDROCHLORIDE SESQUIHYDRATE (CYPROHEPTADINE HYDROCHLORIDE) (Periactin) 507
Available form 507
Antimycobacterial agents 515
DAPSONE 516
Available forms 516
Action 516
Use 516
Dose 516
Adverse effects 517
Interactions 517
Nursing points/Cautions 517
Patient teaching and advice 517
ETHAMBUTOL HYDROCHLORIDE (Myambutol) 518
Available forms 518
Antineoplastic agents 527
General Adverse effects of antineoplastic agents 528
General Interactions of antineoplastic agents 528
General Nursing points/Cautions for antineoplastic agents 528
General Patient teaching and advice for antineoplastic agents 530
ABIRATERONE ACETATE (Zytiga) 531
Available form 531
Action 531
Use 531
Dose 531
Adverse effects 531
Interactions 531
Nursing points/Cautions 531
Antineoplastic support agents 642
AMIFOSTINE (Ethyol) 642
Available form 642
Action 642
Use 642
Dose 642
Adverse effects 642
Interactions 642
Nursing points/Cautions 642
Patient teaching and advice 643
ANCESTIM (Stemgen) 643
Available form 643
Action 643
Use 643
Dose 643
Adverse effects 643
Nursing points/Cautions 644
Patient teaching and advice 644
MESNA (Uromitexan) 644
Available forms 644
Action 644
Use 644
Dose 644
Adverse effects 645
Interactions 645
Nursing points/Cautions 645
Patient teaching and advice 645
PALIFERMIN (Kepivance) 645
Available form 645
Action 645
Use 645
Anti-parkinson’s agents 655
Anticholinergic Anti-Parkinson’s Agents 656
General Actions of anticholinergic anti-Parkinson’s agents 656
General Uses of anticholinergic anti-Parkinson’s agents 656
General Adverse effects of anticholinergic anti-Parkinson’s agents 656
General Interactions of anticholinergic anti-Parkinson’s agents 656
General Nursing points/Cautions for anticholinergic anti-Parkinson’s agents 657
General Patient teaching and advice for anticholinergic anti-Parkinson’s agents 657
BENZTROPINE MESILATE (BENZTROPINE MESYLATE) (Benztrop, Cogentin) 658
Antiplatelet Agents 678
ABCIXIMAB RMC (ReoPro) 678
Available form 678
Action 678
Use 678
Dose 678
Adverse effects 679
Interactions 679
Nursing points/Cautions 679
ASPIRIN (Aspro preparations, Aspro Clear Extra Strength, Astrix 100, Astrix Tablets, Cardasa, Cardiprin 100, Cartia, Disprin preparations, Solprin, Spren) 680
Antiprotozoal agents 692
ATOVAQUONE (Wellvone Suspension) 692
Available form 692
Action 692
Use 692
Dose 692
Adverse effects 692
Interactions 693
Nursing points/Cautions 693
Patient teaching and advice 693
Note 693
METRONIDAZOLE (Flagyl, Flagyl S Suspension, Metrogyl, Metronidazole Intravenous Infusion, Metronide, Rozex Cream and Gel, Zidoval Vaginal Gel) 693
Available forms 693
Action 693
Use 693
Dose 694
Adverse effects 694
Interactions 694
Nursing points/Cautions 695
Patient teaching and advice 695
PENTAMIDINE ISETIONATE (PENTAMIDINE ISETHIONATE) (DBL Pentamidine Isethionate for Injection) 696
Available form 696
Action 696
Use 696
Dose 696
Adverse effects 696
Interactions 697
Nursing points/Cautions 697
Patient teaching and advice 697
PYRIMETHAMINE (Daraprim) 697
Available form 697
Action 697
Use 697
Dose 698
Adverse effects 698
Interactions 698
Nursing points/Cautions 698
Patient teaching and advice 698
TINIDAZOLE (Fasigyn, Simplotan) 698
Available form 698
Action 698
Use 698
Dose 699
Adverse effects 699
Interactions 699
Nursing points/Cautions 699
Patient teaching and advice 699
Antipsychotic and mood-stabilising agents 701
General Adverse effects of antipsychotics 702
General Interactions of antipsychotics 703
General Nursing points/Cautions for antipsychotics 704
General Patient teaching and advice for antipsychotics 705
AMISULPRIDE (Amipride, Solian, Sulprix) 706
Available forms 706
Action 706
Use 706
Dose 706
Adverse effects 706
Interactions 706
Nursing points/Cautions 706
Patient teaching and advice 706
ARIPIPRAZOLE (Abilify, Ablify Maintena) 707
Available forms 707
Action 707
Use 707
Dose 707
Adverse effects 707
Interactions 707
Nursing points/Cautions 707
Antiulcer agents 733
Histamine H2-Receptor Antagonists 734
General Actions of H2-receptor antagonists 734
General Uses of H2-receptor antagonists 734
General Nursing points/Cautions for H2-receptor antagonists 734
General Patient teaching and advice for H2-receptor antagonists 734
CIMETIDINE (Magicul, Tagamet) 735
Available forms 735
Action 735
Use 735
Dose 735
Adverse effects 735
Interactions 735
Nursing points/Cautions 735
Patient teaching and advice 735
FAMOTIDINE (Ausfam, Famohexal, Pamacid, Pepzan) 736
Antiviral agents 748
General Adverse effects of antiretroviral agents 748
General Interactions of antiretroviral agents 749
General Nursing points/Cautions for antiretroviral agents 749
General Patient teaching and advice for antiretroviral agents 750
Note 751
ABACAVIR (Ziagen) 751
Available forms 751
Action 751
Use 751
Dose 751
Adverse effects 751
Nursing points/Cautions 751
Patient teaching and advice 751
Note 752
ACICLOVIR (Aciclovir Intravenous Infusion, AciVision, Acivir Cold Sore Cream, Acyclo-V, Blistex Antiviral Cold Sore Cream, Lovir, Lovir Cold Sore Cream, Nyal Antiviral Cold Sore Cream, Ozvir, Zovirax Cold Sore Cream, Zovirax Ophthalmic Ointment, Zovirax Tablets) 752
Available forms 752
Action 752
Use 752
Dose 752
Genital herpes 752
Herpes zoster (shingles) 752
Herpes simplex infections 752
Herpes simplex encephalitis (immunocompetent or immunocompromised) 752
Advanced symptomatic HIV disease 752
Adverse effects 753
Interactions 753
Nursing points/Cautions 753
Patient teaching and advice 753
ADEFOVIR DIPIVOXIL (Hepsera) 754
Available form 754
Action 754
Use 754
Dose 754
Adverse effects 754
Interactions 754
Nursing points/Cautions 754
Patient teaching and advice 755
ASUNAPEVIR (Sunvepra) 755
Available form 755
Action 755
Use 755
Dose 755
Adverse effects 755
Interactions 755
Nursing Points/Cautions 755
Patient teaching and advice 756
ATAZANAVIR (Reyataz) 756
Available forms 756
Action 756
Use 756
Dose 756
Therapy naive patient 756
Therapy experienced patient 756
Adverse effects 756
Interactions 756
Nursing points/Cautions 757
Patient teaching and advice 757
Note 757
BOCEPREVIR (Victrelis) 757
Available form 757
Action 758
Use 758
Dose 758
Adverse effects 758
Interactions 758
Nursing points/Cautions 758
Patient teaching and advice 759
CIDOFOVIR (Vistide) 759
Available form 759
Action 759
Use 759
Dose 759
Adverse effects 759
Interactions 760
Nursing points/Cautions 760
Patient teaching and advice 760
DACLATASVIR (Daklinza) 760
Available forms 760
Action 760
Use 761
Dose 761
Adverse effects 761
Interactions 761
Nursing points/Cautions 761
Patient teaching and advice 761
DARUNAVIR (Prezista) 761
Available forms 761
Action 762
Use 762
Dose 762
Adverse effects 762
Interactions 762
Nursing points/Cautions 762
Patient teaching and advice 762
DIDANOSINE (Videx EC) 763
Available forms 763
Action 763
Use 763
Dose 763
Adverse effects 763
Interactions 763
Nursing points/Cautions 763
Bladder function disorder agents 799
ALFUZOSIN HYDROCHLORIDE (Xatral SR) 800
Available form 800
Action 800
Use 800
Dose 800
Adverse effects 800
Interactions 800
Nursing points/Cautions 800
Patient teaching and advice 800
BETHANECHOL CHLORIDE (Urocarb) 801
Available form 801
Bone and calcium regulating agents 811
Bisphosphonates 812
General Actions of bisphosphonates 812
General Uses of bisphosphonates 812
General Adverse effects of bisphosphonates 813
General Interactions of bisphosphonates 813
General Nursing points/Cautions for bisphosphonates 813
General Patient teaching and advice for bisphosphonates 814
ALENDRONIC ACID (ALENDRONATE SODIUM) (Adronat, Alendro, Alendrobell, Densate, Fonat, Fosamax, Fosamax Once Weekly, Ossmax) 815
Cardiac glycosides 831
DIGOXIN (Lanoxin, Sigmaxin) 831
Available forms 831
Action 831
Use 831
Dose 831
Digitalising loading dose 831
Maintenance dose 832
Adverse effects 832
Interactions 832
Nursing points/Cautions 833
Patient teaching and advice 834
Note 835
MILRINONE LACTATE (Milrinone GH Concentrate for Infusion, Primacor Injection) 835
Available form 835
Action 835
Use 835
Dose 835
Adverse effects 835
Nursing points/Cautions 835
Cholinergic and anticholinergic agents 836
Cholinergic (Parasympathomimetic) Agents 836
General Actions of cholinergic agents 836
General Adverse effects of cholinergic agents 836
NEOSTIGMINE METHYLSULFATE (Neostigmine Injection BP) 837
Available forms 837
Action 837
Use 837
Dose 837
Adverse effects 837
Interactions 837
Nursing points/Cautions 837
PYRIDOSTIGMINE BROMIDE (Mestinon) 838
Available forms 838
Action 838
Use 838
Dose 838
Adverse effects 838
Interactions 838
Nursing points/Cautions 838
Patient teaching and advice 839
Anticholinergic Agents 839
General Actions of anticholinergic agents 839
General Adverse effects of anticholinergics 839
General Interactions of anticholinergics 840
General Nursing points/Cautions for anticholinergics 840
General Patient teaching and advice for anticholinergics 841
ATROPINE SULFATE MONOHYDRATE (ATROPINE SULFATE) (Atropine Injection, Atropine Sulfate Injection BP, Atropt, Minims Atropine Eye Drops) 841
Available forms 841
Action 841
Use 841
Dose 841
Corticosteroids 845
General Actions of coticosteroids 845
General Uses of coticosteroids 846
General Adverse effects of coticosteroids 846
General Interactions of coticosteroids 847
General Nursing points/Cautions for coticosteroids 848
Topical 850
Ophthalmic 851
Withdrawal 851
General Patient teaching and advice for coticosteroids 852
Topical (cream, ointment, lotion) 852
Nasal spray instillation 853
Eye drop instillation 853
BETAMETHASONE ACETATE, SODIUM PHOSPHATE 854
BETAMETHASONE DIPROPRONATE 854
BETAMETHASONE VALERATE (Antroquoril, Betnovate preparations, Celestone M Cream and Ointment, Cortival) 854
Available forms 854
Action 854
Use 854
Dose 854
Parenteral (1 mL = 5.7 mg beclomethasone) 854
Topical 854
Adverse effects 855
Interactions 855
Nursing points/Cautions/Withdrawal 855
Patient teaching and advice 855
Note 855
BUDESONIDE (Budamax, Budenofalk, Budenofalk Foam Enema, Cortiment, Entocort, Pulmicort, Rhinocort, Rhinocort Hayfever) 855
Available forms 855
Cough suppressants, expectorants and mucolytics 869
AMMONIUM CHLORIDE (Nyal Bronchitis Cough Medicine) 869
Available form 869
Action 869
Use 869
Dose 869
Nursing points/Cautions 869
Patient teaching and advice 869
Dermatological agents 876
Topical Ectoparasitical Agents 876
Pediculosis (Lice Infestation) 876
General Patient Teaching and Advice for pediculicides 876
BENZYL ALCOHOL (NeutraLice Advance) 877
Disease-modifying antirheumatic drugs (DMARDs) 889
Conventional Dmards 890
AURANOFIN (Ridaura) 890
Available form 890
Action 890
Use 890
Dose 890
Adverse effects 890
Interactions 890
Nursing points/Cautions 890
Patient teaching and advice 891
CICLOSPORIN (CYCLOSPORIN) (Neoral, Sandimmun) 891
Available forms 891
Action 891
Use 891
Dose 891
Adverse effects 892
Interactions 892
Nursing points/Cautions 893
Patient teaching and advice 894
HYDROXYCHLOROQUINE SULFATE (Hequinel, Plaquenil) 895
Available form 895
Action 895
Use 895
Dose 895
Adverse effects 895
Interactions 896
Nursing points/Cautions 896
Patient teaching and advice 896
LEFLUNOMIDE (Arabloc, Arava, Lunava) 897
Available forms 897
Action 897
Use 897
Dose 897
Adverse effects 897
Interactions 897
Nursing points/Cautions 898
Patient teaching and advice 898
METHOTREXATE (Methaccord, Methoblastin, Methotrexate Injection and Tablets, Trexject) 899
Available forms 899
Action 899
Use 899
Dose 899
Adverse effects 899
Interactions 900
Nursing points/Cautions 900
Patient teaching and advice 901
PENICILLAMINE (D Penamine) 902
Available forms 902
Action 902
Use 902
Dose 902
Adverse effects 902
Interactions 903
Nursing points/Cautions 903
Patient teaching and advice 903
SODIUM AUROTHIOMALATE (Gold Salt) (Myocrisin) 904
Available forms 904
Action 904
Use 904
Dose 904
Rheumatoid arthritis 904
Still’s disease 904
Adverse effects 904
Interactions 904
Nursing points/Cautions 904
Patient teaching and advice 905
SULFASALAZINE (Pyralin EN, Salazopyrin, Salazopyrin EN-Tabs) 905
Available forms 905
Action 905
Use 905
Dose 905
Adverse effects 905
Interactions 906
Nursing points/Cautions 906
Patient teaching and advice 906
Tumour Necrosis Factor Alpha (TNF-α) Antagonists 907
General Actions of TNF-α antagonists 907
General Adverse effects of TNF-α antagonists 907
General Interactions of TNF-α antagonists 907
General Nursing points/Cautions for TNF-α antagonists 907
General Patient teaching and advice for TNF-α antagonists 908
ADALIMUMAB (Humira) 909
Available forms 909
Action 909
Use 909
Dose 910
Adverse effects 910
Interactions 910
Nursing points/Cautions 910
Patient teaching and advice 910
CERTOLIZUMAB PEGOL (Cimzia) 910
Available form 910
Action 910
Use 910
Diuretics 923
General Nursing points/Cautions for diuretics 923
General Patient teaching and advice for diuretics 924
Carbonic Anhydrase Inhibitors 925
ACETAZOLAMIDE (Diamox, Glaumax Powder for Injection) 925
Available forms 925
Action 925
Use 925
Dose 925
Adverse effects 925
Interactions 925
Nursing points/Cautions 926
Patient teaching and advice 926
High-Ceiling (Loop) Diuretics 926
General Actions of high-ceiling (loop) diuretics 926
General Uses of high-ceiling (loop) diuretics 926
General Adverse effects of high-ceiling (loop) diuretics 927
General Interactions of high-ceiling (loop) diuretics 927
General Nursing points/Cautions for high-ceiling (loop) diuretics 927
General Patient teaching and advice for high-ceiling (loop) diuretics 928
BUMETANIDE (Burinex) 928
Available form 928
Action 928
Use 928
Dose 928
Drug dependence 945
ACAMPROSATE CALCIUM (Campral) 945
Available form 945
Action 945
Use 945
Dose 945
Adverse effects 945
Interactions 946
Nursing points/Cautions 946
Patient teaching and advice 946
BUPRENORPHINE (Norspan Transdermal Patch, Subutex, Temgesic) 946
Available forms 946
Erectile dysfunction agents 958
Intracavernosal Administration 959
General Adverse effects of intracavernosal administration 959
General Interactions of intracavernosal administration 959
General Nursing points/Cautions for intracavernosal administration 959
General Patient teaching and advice for intracavernosal administration 959
ALPROSTADIL (prostaglandin E1) (Caverject, Caverject Impulse, Prostin VR) 960
Available forms 960
Action 960
Use 960
Dose 960
Adverse effects/interaction 960
Nursing points/Cautions 960
Patient teaching and advice 960
Note 960
PAPAVERINE HYDROCHLORIDE (DBL Papaverine Hydrochloride Injection) 961
Available forms 961
Action 961
Use 961
Dose 961
Adverse effects 961
Interactions 961
Nursing points and Cautions 961
Patient teaching and advice 961
Phosphodiesterase type 5 (PDE5) inhibitors 962
General Actions of PDE5 inhibitors 962
General Adverse effects of PDE5 inhibitors 962
General Interactions of PDE5 inhibitors 962
General Nursing points/Cautions for PDE5 inhibitors 962
General Patient teaching and advice for PDE5 inhibitors 963
SILDENAFIL (Revatio, Silaran, Vasafil, Vedafil, Viagra) 963
Available forms 963
Action 963
Use 963
Dose 963
Adverse effects 964
Interactions 964
Nursing points/Cautions 964
Patient teaching and advice 964
TADALAFIL (Adcirca, Cialis) 964
Available forms 964
Action 964
Use 964
Dose 964
Adverse effects 965
Interactions 965
Eye, ear, nose and throat agents 969
The Eye 969
General Nursing points/Cautions for eye preparations 969
Instillation of eye drops 969
Insertion of eye ointment 970
General Patient teaching and advice for eye preparations 970
Cycloplegic and Mydriatic Drops 971
General Actions of cycloplegic and mydriatic drops 971
General Adverse effects of cycloplegic and mydriatic drops 971
General Interactions of cycloplegic and mydriatic drops 972
General Nursing points/Cautions for cycloplegic and mydriatic drops 972
General Patient teaching and advice for cycloplegic and mydriatic drops 972
ATROPINE SULFATE MONOHYDRATE (ATROPINE SULFATE) (Atropt, Minims Atropine Eye Drops) 972
Available form 972
Action 972
Use 972
Fibrinolytic agents 993
General Adverse effects of fibrinolytic agents 993
General Interactions of fibrinolytic agents 993
General Nursing points/Cautions for fibrinolytic agents 993
ALTEPLASE (Actilyse) 995
Available forms 995
Action 995
Use 995
Dose 995
Adverse effects 995
Interactions 995
Nursing points/Cautions 995
PROTEIN C (Ceprotin) 996
Available form 996
Action 996
Use 996
Dose 997
Adverse effects 997
Interactions 997
Nursing points/Cautions 997
Patient teaching and advice 997
RETEPLASE (Rapilysin) 998
Available form 998
Gastrointestinal agents (miscellaneous) 1000
MEBEVERINE HYDROCHLORIDE (Colese, Colofac) 1000
Available form 1000
Action 1000
Use 1000
Dose 1000
Adverse effects 1000
Nursing points/Cautions 1000
Patient teaching and advice 1000
URSODEOXYCHOLIC ACID (Urso, Ursodox GH, Ursofalk, Ursosan) 1001
Available forms 1001
Action 1001
Use 1001
Dose 1001
Adverse effects 1001
Interactions 1001
Nursing points/Cautions 1001
Patient teaching and advice 1001
Agents Used in Inflammatory Bowel Disease 1002
BALSALAZIDE SODIUM (Colazide) 1002
Available form 1002
Action 1002
Use 1002
Dose 1002
Adverse effects 1002
Interactions 1002
Nursing points/Cautions 1002
Patient teaching and advice 1002
MESALAZINE (Mesasal, Mezavant, Pentasa, Pentasa Oral, Salofalk preparations) 1003
Available forms 1003
Action 1003
Use 1003
Dose 1003
Adverse effects 1003
Interactions 1003
Nursing points/Cautions 1004
Patient teaching and advice 1004
OLSALAZINE SODIUM (Dipentum) 1005
Available forms 1005
Action 1005
Use 1005
Dose 1005
Adverse effects 1005
Interactions 1005
General anaesthetics 1010
Dose 1011
General Adverse effects of general anaesthetics 1011
General Interactions of general anaesthetics 1011
General Nursing points/Cautions for general anaesthetics 1011
General Patient teaching and advice for General anaesthetics 1012
DESFLURANE (Suprane) 1012
Available form 1012
Properties and actions 1012
Use 1012
Adverse effects 1012
Interactions 1012
Haemopoietic agents 1020
General Actions of haemopoietic agents 1020
General Adverse effects of haemopoietic agents 1020
General Nursing points/Cautions for haemopoietic agents 1021
General Patient teaching and advice for haemopoietic agents 1022
DARBEPOETIN ALFA (Aranesp) 1023
Available forms 1023
Action 1023
Use 1023
Dose 1023
Adverse effects 1024
Nursing points/Cautions 1024
Patient teaching and advice 1024
EPOETIN ALFA (Eprex) 1024
Available forms 1024
Action 1024
Use 1024
Dose 1024
Adverse effects 1025
Interactions 1025
Nursing points/Cautions 1025
Patient teaching and advice 1025
EPOETIN BETA (NeoRecormon) 1025
Available forms 1025
Action 1025
Use 1025
Dose 1026
Adverse effects 1026
Nursing points/Cautions 1026
Patient teaching and advice 1026
EPOETIN LAMBDA (Novicrit) 1027
Available forms 1027
Action 1027
Use 1027
Dose 1027
Adverse effects 1027
Interactions 1027
Nursing points/Cautions 1027
Haemostatics 1029
ELTROMBOPAG OLAMINE (Revolade) 1029
Available forms 1029
Action 1029
Use 1030
Dose 1030
Adverse effects 1030
Interactions 1030
Nursing points/Cautions 1030
Patient teaching and advice 1031
FIBRINOGEN (RiaSTAP) 1031
Available form 1031
Action 1031
Use 1031
Dose 1031
Adverse effects 1031
Nursing points/Cautions 1031
Note 1032
ORNIPRESSIN (Por-8 Ferring) 1032
Available form 1032
Hypothalamic and pituitary hormones 1045
Gonadotrophin-Releasing Hormone 1046
GOSERELIN ACETATE (Zoladex 3.6 mg Implant, Zoladex 10.8 mg Implant) 1046
Available forms 1046
Action 1046
Use 1046
Dose 1046
Adverse effects 1047
Interactions 1047
Nursing points/Cautions 1047
Patient teaching and advice 1048
Note 1048
LEUPRORELIN ACETATE (Eligard, Lucrin, Lucrin Depot) 1048
Available forms 1048
Action 1048
Use 1048
Dose 1048
Adverse effects 1048
Interactions 1049
Nursing points/Cautions 1049
Patient teaching and advice 1049
Growth Hormone Release-Inhibiting Factor 1050
LANREOTIDE ACETATE (Somatuline Autogel, Somatuline LA) 1050
Available forms 1050
Action 1050
Use 1050
Dose 1050
Acromegaly 1050
Carcinoid tumour 1050
GEP endocrine tumours 1050
Adverse effects 1050
Interactions 1050
Nursing points/Cautions 1051
Patient teaching and advice 1051
OCTREOTIDE (DBL Octreotide Injection, Octreotide MaxRx, Octreotide Sun, Sandostatin, Sandostatin LAR) 1051
Available forms 1051
Action 1051
Use 1051
Dose 1051
Acromegaly 1051
GEP endocrine tumour 1052
Complications after pancreatic surgery 1052
Advanced neuroendocrine tumour of midgut 1052
Adverse effects 1052
Interactions 1052
Nursing points/Cautions 1052
Patient teaching and advice 1053
PASIREOTIDE (Signifor, Signifor LAR) 1053
Available form 1053
Action 1053
Use 1053
Dose 1054
Adverse effects 1054
Interactions 1054
Nursing points/Cautions 1054
Patient teaching and advice 1055
Anterior Pituitary Hormones 1056
Growth Hormone (Somatotropic Hormones) 1056
SOMATROPIN (SOMATOTROPHIN/SOMATOTROPIN) (Genotropin, Genotropin GoQuick, Genotropin MiniQuick, Humatrope, Norditropin, NutropinAq Cartridge Solution for Injection, Omnitrope, Saizen, SciTropin A, Zomacton) 1056
Available forms 1056
Action 1056
Use 1056
Dose 1056
Adverse effects 1057
Interactions 1057
Nursing points/Cautions 1057
Patient teaching and advice 1058
TETRACOSACTIDE (TETRACOSACTRIN) (Synacthen, Synacthen Depot) 1058
Available forms 1058
Action 1058
Use 1059
Dose 1059
Adverse effects 1059
Interactions 1059
Nursing points/Cautions 1059
Patient teaching and advice 1060
Prolactin Suppression 1061
QUINAGOLIDE HYDROCHLORIDE (Norprolac) 1061
Available forms 1061
Action 1061
Use 1061
Dose 1061
Adverse effects 1061
Interactions 1061
Nursing points/Cautions 1061
Patient teaching and advice 1061
Posterior Pituitary Hormones 1062
Antidiuretic Hormone (ADH) 1062
DESMOPRESSIN (Minirin Melt, Minirin Tablets) DESMOPRESSIN ACETATE (Minirin Injection, Minirin Nasal Spray or Solution, Octostim Injection) 1062
Available forms 1062
Action 1062
Use 1062
Dose 1062
Adverse effects 1063
Interactions 1063
Nursing points/Cautions 1063
Patient teaching and advice 1064
TERLIPRESSIN (Glypressin Solution, Lucassin) 1065
Available form 1065
Action 1065
Use 1065
Dose 1065
Adverse effects 1065
Interactions 1065
Nursing points/Cautions 1065
VASOPRESSIN (Pitressin) 1066
Available form 1066
Action 1066
Use 1066
Dose 1066
Adverse effects 1066
Interactions 1066
Nursing points/Cautions 1066
Patient teaching and advice 1067
Immunomodifiers 1068
General Adverse effects of immunomodifiers 1068
General Interactions of immunomodifiers 1068
General Nursing points/Cautions for immunomodifiers 1068
General Patient teaching and advice for immunomodifiers 1069
ANTITHYMOCYTE GLOBULIN 1069
ANTITHYMOCYTE GLOBULIN (RABBIT) (Thymoglobuline) 1069
Available form 1069
Action 1069
Use 1069
Dose 1069
Adverse effects 1070
Interactions 1070
Nursing points/Cautions 1070
Patient teaching and advice 1071
APREMILAST (Otezla) 1071
Available form 1071
Action 1071
Use 1071
Dose 1071
Adverse effects 1071
Interactions 1071
Nursing points/Cautions 1071
Patient teaching and advice 1072
AZATHIOPRINE (Azamun, Azapin, Azran, Imazan, Imuran, Thioprine) 1072
Available forms 1072
Action 1072
Use 1072
Dose 1072
Adverse effects 1072
Interactions 1072
Nursing points/Cautions 1073
Patient teaching and advice 1073
BASILIXIMAB (Simulect) 1073
Available form 1073
Laxatives 1108
General Uses of laxatives 1108
General Adverse effects of laxatives 1108
General Nursing points/Cautions for laxatives 1109
General Patient teaching and advice for laxatives 1109
Bulk-Forming Laxatives 1110
General Actions of bulk-forming laxatives 1110
ISPAGHULA (Fybogel) 1110
Lipid regulating agents 1122
HMG-CoA Reductase Inhibitors (Statins) 1123
General Actions of statins 1123
General Uses of statins 1124
General Adverse effects of statins 1124
General Interactions of statins 1124
General Nursing points/Cautions for statins 1124
General Patient teaching and advice for statins 1125
ATORVASTATIN (Atorvachol, Lipitor, Lorstat, Torvastat, Trovas) 1125
Available forms 1125
Action 1126
Use 1126
Local anaesthetics 1139
General Actions of local anaesthetics 1139
Surface (topical) anaesthesia 1139
Local (infiltration) anaesthesia 1139
Regional nerve block anaesthesia 1139
Spinal anaesthesia 1139
General Uses of local anaesthetics 1140
General Doses for local anaesthetics 1140
General Adverse effects of local anaesthetics 1140
General Interactions of local anaesthetics 1140
General Nursing points/Cautions for local anaesthetics 1140
General Patient teaching and advice for local anaesthetics 1142
ARTICAINE HYDROCHLORIDE 1142
Metabolic disorders agents 1151
AGALSIDASE ALFA (GHU) (Replagal) 1151
Available form 1151
Action 1151
Use 1151
Dose 1151
Adverse effects 1151
Interactions 1152
Nursing points/Cautions 1152
Patient teaching and advice 1152
AGALSIDASE BETA (RCH) (Fabrazyme) 1152
Available forms 1152
Action 1152
Use 1152
Dose 1152
Adverse effects 1152
Interactions 1153
Nursing points/Cautions 1153
Patient teaching and advice 1153
ALGLUCOSIDASE ALFA (RHU) (Myozyme) 1153
Available form 1153
Action 1153
Use 1154
Dose 1154
Adverse effects 1154
Nursing points/Cautions 1154
Patient teaching and advice 1154
ASFOTASE ALFA (Strensiq) 1155
Available form 1155
Action 1155
Use 1155
Dose 1155
Adverse effects 1155
Interaction 1155
Nursing points/Cautions 1155
Movement disorder agents 1169
Multiple Sclerosis 1169
ALEMTUZUMAB (Lemtrada, MabCampath) 1170
Available form 1170
Action 1170
Use 1170
Dose 1170
Adverse effects 1170
Interactions 1170
Nursing points/Cautions 1170
Patient teaching and advice 1171
DIMETHYL FUMARATE (Tecfidera) 1171
Available form 1171
Action 1171
Use 1171
Muscle relaxants 1187
BACLOFEN (Bacthecal, Clofen, Lioresal, Lioresal Intrathecal, Stelax) 1187
Available forms 1187
Action 1187
Use 1187
Dose 1187
Adverse effects 1188
Interactions 1188
Nursing points/Cautions 1188
Patient teaching and advice 1190
BOTULINUM TOXIN TYPE A (Botox, Dysport) 1190
Available forms 1190
Action 1190
Use 1190
Dose 1191
Adverse effects 1191
General 1191
Blepharospasm 1191
Strabismus 1191
Spasmodic dysphonia 1191
Cervical dystonia (spasmodic torticollis) 1191
Nerve VII disorder 1191
Focal spasticity (upper limb, post-stroke) 1191
Hyperhidrosis 1191
Focal spasticity (children) 1191
Chronic migraine 1191
Overactive bladder/Neurogenic detrusor overactivity 1191
Glabellar lines 1191
Crow’s feet 1191
Forehead lines 1191
Interactions 1191
Nursing points/Cautions 1192
Patient teaching and advice 1193
DANTROLENE SODIUM HEMIHEPTAHYDRATE (DANTROLENE SODIUM) (Dantrium Capsules, Dantrium Powder for Injection) 1194
Available forms 1194
Action 1194
Use 1194
Dose 1194
Adverse effects 1194
Interactions 1194
Nursing points/Cautions 1194
Patient teaching and advice 1195
INCOBOTULINUMTOXINA (Xeomin) 1195
Available form 1195
Action 1195
Use 1195
Dose 1195
Adverse effects 1196
General 1196
Blepharospasm 1196
Cervical dystonia (spasmodic torticollis) 1196
Spasticity (upper limb, post-stroke) 1196
Glabellar lines 1196
Interactions 1196
Nursing points/Cautions 1196
Patient teaching and advice 1197
ORPHENADRINE CITRATE (Norflex) 1197
Available form 1197
Action 1197
Neuromuscular blocking agents 1200
Non-Depolarising Blocking Agents 1200
General Actions of non-depolarising blocking agents 1200
General Uses of non-depolarising blocking agents 1200
General Adverse effects of non-depolarising blocking agents 1201
General Interactions of non-depolarising blocking agents 1201
General Nursing points/Cautions for non-depolarising blocking agents 1201
General Patient teaching and advice for non-depolarising blocking agents 1202
ATRACURIUM BESYLATE (DBL Atracurium Besylate Injection, Tracrium Injectable) 1203
Opioid analgesics 1209
General Actions of opioids 1210
General Adverse effects of opioids 1210
General Interactions of opioids 1210
General Nursing points/Cautions for opioids 1211
General Patient teaching and advice for opioids 1213
ALFENTANIL HYDROCHLORIDE (Alfentanil GH, Rapifen) 1213
Available forms 1213
Action 1213
Use 1213
Dose 1213
Adverse effects 1213
Interactions 1213
Nursing points/Cautions 1214
Patient teaching and advice 1214
BUPRENORPHINE (Norspan Transdermal Patch, Subutex, Temgesic) 1214
Available forms 1214
Action 1214
Use 1214
Dose 1214
Adverse effects 1214
Interactions 1215
Nursing points/Cautions 1215
Patient teaching and advice 1215
Note 1216
CODEINE PHOSPHATE HEMIHYDRATE (CODEINE PHOSPHATE) (Actacode Linctus, Codeine Linctus, Codeine Phosphate Tablets) 1216
Available forms 1216
Action 1216
Pregnancy, childbirth and breastfeeding 1233
Agents Used to Treat Infertility 1233
General Adverse effects of infertility agents 1234
General Nursing points/Cautions for infertility agents 1235
General Patient teaching and advice for infertility agents 1235
CETRORELIX ACETATE (Cetrotide) 1235
Available forms 1235
Pulmonary hypertension agents 1266
AMBRISENTAN (Volibris) 1266
Available forms 1266
Action 1266
Use 1266
Dose 1266
Adverse effects 1266
Interactions 1267
Nursing points/Cautions 1267
Patient teaching and advice 1267
BOSENTAN MONOHYDRATE (Tracleer) 1267
Available forms 1267
Action 1267
Use 1267
Dose 1268
Adverse effects 1268
Interactions 1268
Nursing points/Cautions 1268
Patient teaching and advice 1268
EPOPROSTENOL (Flolan, Veletri) 1269
Available forms 1269
Action 1269
Use 1269
Dose 1269
Adverse effects 1269
Interactions 1269
Nursing points/Cautions 1269
Patient teaching and advice 1270
ILOPROST TROMETAMOL (Ventavis) 1270
Available form 1270
Action 1270
Use 1270
Dose 1270
Adverse effects 1271
Interactions 1271
Nursing points/Cautions 1271
Patient teaching and advice 1271
MACITENTAN (Opsumit) 1271
Available form 1271
Action 1272
Use 1272
Dose 1272
Adverse effects 1272
Interactions 1272
Nursing points/Cautions 1272
Patient teaching and advice 1272
SELEXIPAG (Uptravi) 1273
Available form 1273
Action 1273
Use 1273
Dose 1273
Adverse effects 1273
Interactions 1273
Nursing points/Cautions 1273
Patient teaching and advice 1274
TREPROSTINIL SODIUM (Remodulin) 1274
Available forms 1274
Action 1274
Use 1274
Dose 1274
Adverse effects 1274
Interactions 1274
Nursing points/Cautions 1275
Patient teaching and advice 1275
Sedatives and hypnotics 1276
General Adverse effects of sedatives and hypnotics 1277
General Interactions of sedatives and hypnotics 1277
General Nursing points/Cautions for sedatives and hypnotics 1277
General Patient teaching and advice for sedatives and hypnotics 1278
CHLORAL HYDRATE (Chloral Hydrate Mixture) 1279
Available form 1279
Action 1279
Use 1279
Dose 1279
Adverse effects 1279
Interactions 1279
Nursing points/Cautions 1279
Patient teaching and advice 1280
DEXMEDETOMIDINE (Precedex) 1280
Available form 1280
Action 1280
Use 1280
Dose 1280
Adverse effects 1280
Interactions 1280
Nursing points/Cautions 1280
FLUNITRAZEPAM (Hypnodorm) 1281
Sex hormones 1288
Androgens and Anabolic Steroids 1288
General Actions of androgens and anabolic steroids 1288
General Uses of androgens and anabolic steroids 1289
General Adverse effects of androgens and anabolic steroids 1289
General Interactions of androgens and anabolic steroids 1289
General Nursing points/Cautions for androgens and anabolic steroids 1289
General Patient teaching and advice for androgens and anabolic steroids 1290
MESTEROLONE (Proviron) 1291
Stimulants 1325
General Adverse effects of stimulants 1325
General Nursing points/Cautions for stimulants 1326
General Patient teaching and advice for stimulants 1326
ARMODAFINIL (Nuvigil) 1327
Available form 1327
Action 1327
Use 1327
Dose 1327
Adverse effects 1327
Interactions 1327
Nursing points/Cautions 1327
Patient teaching and advice 1328
ATOMOXETINE (Strattera) 1328
Available forms 1328
Action 1328
Use 1328
Dose 1328
Adverse effects 1328
Interactions 1328
Nursing points/Cautions 1329
Patient teaching and advice 1329
CAFFEINE (No Doz) 1329
Sympathomimetic agents 1335
General Interactions of sympathomimetic agents 1335
General Nursing points/Cautions for sympathomimetic agents 1336
ADRENALINE (EPINEPHRINE) (Epipen, Epipen Jr) ADRENALINE (EPINEPHRINE) ACID TARTRATE (Adrenaline–Link Injection BP, Aspen Adrenaline Injection) ADRENALINE (EPINEPHRINE) HYDROCHLORIDE (Adrenaline Hydrochloride Injection 1 : 10,000 (Min-I-Jet)) 1336
Available forms 1336
Action 1337
Use 1337
Dose 1337
Anaphylaxis 1337
Cardiopulmonary resuscitation (in absence of ventricular fibrillation) 1337
Adverse effects 1337
Interactions 1338
Nursing points/Cautions 1338
Patient teaching and advice 1338
Note 1339
DOBUTAMINE HYDROCHLORIDE (DBL Dobutamine Hydrochloride Injection, Dobutrex) 1339
Available forms 1339
Action 1339
Use 1339
Dose 1339
Adverse effects 1339
Interactions 1339
Nursing points/Cautions 1340
DOPAMINE HYDROCHLORIDE (DBL Sterile Dopamine Concentrate) 1340
Available form 1340
Action 1340
Use 1340
Dose 1341
Adverse effects 1341
Interactions 1341
Nursing points/Cautions 1341
EPHEDRINE SULFATE (DBL Ephedrine Sulfate Injection) 1342
Available form 1342
Action 1342
Use 1342
Dose 1342
Adverse effects 1342
Interactions 1342
Nursing points/Cautions 1342
Note 1343
ISOPRENALINE HYDROCHLORIDE (known as isoproterenol in USA) (Isuprel) 1343
Available forms 1343
Action 1343
Use 1343
Dose 1343
Adverse effects 1344
Interactions 1344
Nursing points/Cautions 1344
METARAMINOL TARTRATE (Metaraminol Montrose) 1344
Available form 1344
Action 1344
Use 1344
Thyroid and antithyroid agents 1348
Thyroid Agents 1350
LIOTHYRONINE SODIUM (Tertroxin) 1350
Available form 1350
Action 1350
Use 1350
Dose 1350
Adverse effects 1350
Interactions 1350
Nursing points/Cautions 1350
Patient teaching and advice 1351
THYROXINE SODIUM (Eltroxin, Eutroxsig, Oroxine) 1351
Available forms 1351
Action 1351
Use 1351
Dose 1351
Adverse effects 1351
Interactions 1351
Nursing points/Cautions 1352
Patient teaching and advice 1352
Antithyroid Agents 1353
CARBIMAZOLE (Carbimazol Aristo, Neo-Mercazole) 1353
Available form 1353
Action 1353
Use 1353
Dose 1353
Adverse effects 1354
Interactions 1354
Nursing points/Cautions 1354
Patient teaching and advice 1354
PROPYLTHIOURACIL (PTU) 1354
Available form 1354
Action 1354
Use 1355
Dose 1355
Adverse effects 1355
Interactions 1355
Nursing points/Cautions 1355
Patient teaching and advice 1355
SODIUM IODIDE (131I) (Sodium Iodide (131I) Capsules (Therapy), (Sodium Iodide (131I) Solution BP (Therapy) 1356
Available forms 1356
Action 1356
Use 1356
Dose 1356
Adverse effects 1356
Interactions 1356
Nursing points/Cautions 1356
Patient teaching and advice 1357
Vaccines, immunoglobulins and antivenoms 1358
Vaccines 1358
General Actions of vaccines 1358
General Uses of vaccines 1358
General Interactions of vaccines 1358
General Nursing points/Cautions for vaccines 1359
General Patient teaching and advice for vaccines 1361
Notes 1362
Overseas travel and vaccination 1362
Healthcare workers and vaccination 1362
BCG VACCINE (BCG Vaccine) 1364
Vasodilators 1400
ALPROSTADIL (prostaglandin E1) (Caverject, Caverject Impulse, Prostin VR) 1400
Available forms 1400
Action 1400
Use 1400
Dose 1400
Adverse effects 1400
Nursing points/Cautions 1400
BETAHISTINE DIHYDROCHLORIDE (Seniere, Serc) 1401
Vitamins, minerals and electrolytes 1403
Vitamins 1403
Vitamin A 1403
VITAMIN A (also known as Retinol) (Blackmores Vitamin A 5000, Nature’s Own Vitamin A 5000 IU, Phebra Vitamin A 50,000 IU) 1403
Available forms 1403
Action 1403
Miscellaneous agents 1437
EICOSAPENTAENOIC ACID/DOCOSAHEXAENOIC ACID (Omacor) 1437
Available form 1437
Action 1437
Use 1437
Dose 1437
Adverse effects 1437
Interactions 1437
Appendix 1: Poisoning and its treatment 1447
Aims 1448
Action 1448
Swallowed poison 1448
Inhaled poison 1448
Poison in contact with skin 1449
Poison in contact with eyes 1449
Hospital management 1449
Treatment with activated charcoal (Carbosorb X) 1450
Action and use 1450
Adult dose 1450
Paediatric dose 1451
Nursing points/Cautions 1451
Note 1451
Appendix 2: Poisons information centres and medicine information centres 1452
Poisons information centres 1452
Appendix 3: Changes to drug names 1454
Appendix 4: Normal Reference Values 1456
Reference intervals for haematology 1456
Reference intervals* for clinical chemistry (blood, serum and plasma) 1458
Reference intervals for therapeutic drug monitoring (serum) 1462
Reference intervals* for clinical chemistry (urine) 1465
Reference intervals for toxic substances 1467
Reference intervals for tests performed on cerebrospinal fluid (CSF) 1468
Reference intervals for tests of gastrointestinal function 1468
Reference intervals for tests of immunological function 1469
Lymphocyte subsets, whole blood, heparinised 1469
Reference values for semen analysis 1470
Bibliography 1471
Glossary 1481
Drug administration 1485
Topical applications 1486
Index 1487
A 1487
B 1496
C 1500
D 1506
E 1511
F 1513
G 1516
H 1518
I 1522
J 1525
K 1525
L 1525
M 1529
N 1534
O 1537
P 1539
Q 1546
R 1546
S 1548
T 1553
U 1557
V 1558
W 1560
X 1560
Y 1560
Z 1560
Havard’s nursing guide to drugs 10e 1563
Common Abbreviations 1563
Times 1563
Routes 1563
Useful units and concentrations 1563
Drug Doses and Drip Rates Calculation Formulae 1564
Oral drugs (solids, liquids) 1564
Parenteral drugs 1564
Solutions (IM, IV injections) 1564
Powders 1564
IV infusions 1564
Infusion pumps 1564
Inside Back Cover ibc1