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Concepts in Pharmacogenomics: Fundamentals and Therapeutic Applications in Personalized Medicine

Concepts in Pharmacogenomics: Fundamentals and Therapeutic Applications in Personalized Medicine

Fundamentals and Therapeutic Applications in Personalized Medicine

Zdanowicz, Martin M.

(2017)

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Book Details

Abstract

As the growing field of pharmacogenomics continues to impact daily practice and offer promising new drug therapies, understanding this complex science is critical for all pharmacists—students, residents, and established practitioners.

To meet this need, ASHP’s Concepts in Pharmacogenomics has been completely updated for the second edition. Edited by Martin M. Zdanowicz, MA, PhD, the new edition covers both the fundamentals of pharmacogenomics and the latest genomic technologies.

Written by pharmacists and geneticists, it not only covers basic science concepts but also includes expanded coverage of therapeutic applications. Each chapter features key definitions, case studies, and clinical pearls, with figures and summary tables to further support learning.

Martin M. Zdanowicz, PhD currently serves as the Associate Dean for Health Studies at the University of Miami School of Nursing and Health Studies. He received a BS in Biology from NYU-Polytechnic, an MA in biology/physiology from SUNY Binghamton and a PhD in Pharmaceutical Sciences (Pharmacology) from St. John’s University. After completing his doctorate, he was a research associate at North Shore University Hospital-Cornell Medical College in the area of endocrinology and metabolism. A the Massachusetts College of Pharmacy and Health Sciences, he was a full-time faculty member and served as Chair of Pharmaceutical Sciences and Director of Graduate Studies. Dr. Zdanowicz moved to the South University School of Pharmacy in Savannah, Georgia, where he served as faculty and chair of Pharmaceutical Sciences. Teaching areas include pharmacology, pathophysiology and pharmacogenomics.
 
Zdanowicz has received the Trustee’s Awarded for teaching excellence and was voted pharmacy teacher of the year six times by students at two institutions. He received the Teacher of the Year award in 2015 from the School of Nursing and Health Studies at the University of Miami. His current research interests include pharmacogenomics, drugs of abuse, curriculum development and active learning techniques. Dr. Zdanowicz holds membership in a number of professional societies and has published numerous peer-reviewed articles and several textbooks

Table of Contents

Section Title Page Action Price
Dedication 3
Contents 5
Contributors 6
Preface 8
PART I: Fundamentals of\rPharmacogenomics 11
Chapter 1--Pharmacogenomics: Current and Future Promise 13
Chapter 2--The Genetic Basis of Pharmacogenomics 29
Chapter 3--Methodologies in\rPharmacogenomics 69
Chapter 4--The Pharmacogenetics of Drug Metabolism 117
Chapter 5--Pharmacogenomics of\rTransport Proteins 161
Chapter 6--Pharmacodynamics and Pharmacogenomics 193
PART II: Applications of Pharmacogenomics in Therapeutics 223
Chapter 7--Cardiovascular Disease 225
Chapter 8--Hematology/Oncology\rPharmacogenomics 267
Chapter 9--Central Nervous System 293
Chapter 10--Infectious Diseases 319
Chapter 11--Respiratory Diseases 337
Chapter 12--Toxicogenomics 367
Chapter 13--The Pharmacogenetics of\rAddiction 385
Chapter 14--Pharmacogenomics and\rDiabetes Mellitus 415
PART III: Important Issues in\rPharmacogenomics 445
Chapter 15--Pharmacogenomic Testing and Drug Labeling 447
Chapter 16--Pharmacogenomics in Practice: The Role of the Pharmacist 463
Chapter 17--Ethics and Pharmacogenomics 477
Chapter 18--Future of Pharmacogenomics in Clinical Practice 501
Index 509