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Mosby's Dental Drug Reference - E-Book

Mosby's Dental Drug Reference - E-Book

Arthur H. Jeske

(2017)

Additional Information

Book Details

Abstract

No dental office should be without this quick-reference drug guide! Mosby's Dental Drug Reference, 12th Edition profiles the most commonly used drugs in dentistry, with emphasis on dental-specific considerations. More than 800 drug monographs make it easy to find information such as dosages, indications, contraindications, interactions, precautions, side effects, and serious reactions. Online resources include over 100 additional drug monographs, photos of common oral complications, patient education guides, and more. From lead editor Arthur Jeske, a well-known researcher and author in dental pharmacology, this pocket-sized reference provides the current, concise drug information you need at the point of care.

  • More than 800 drug monographs include each drug’s generic name, pronunciation, brand names, drug class, controlled substances schedule, mechanism of action, uses or indications, doses and routes of administration, side effects/adverse reactions, contraindications, precautions, pharmacokinetics, drug interactions of concern to dentistry, and more.
  • Detailed dental considerations at the end of each monograph include an easy-to-use, bulleted list of specific dental-related information as well as general drug information.
  • Durable, pocket-sized format provides essential drug information at a glance, and makes this guide ideal for chairside use.
  • Emphasis on oral health, prevention, and treatment from the dental hygienist’s perspective makes it easier to use drug information for patient and family education.
  • Coverage of oral contraceptives provides dental information on these commonly used drugs, often known only by their brand names.
  • Primers in the front of the guide include information on biologic agents, medication-related osteonecrosis of the jaw, and a list of online resources for the management of medically compromised patients along with management of common oral lesions.
  • Evolve companion website includes more than 100 additional monographs, photos of common oral complications, patient education guides, information on herbs and alternative medicine, and more.
  • NEW! More than 50 new monographs include newly released, FDA-approved drugs and up-to-date content on the latest drug therapies.

Table of Contents

Section Title Page Action Price
Front Cover cover
IFC_Evolve page IFC1
Additional Monographs on Evolve IFC2
Mosby's Dental Drug Reference i
Copyright Page iv
Drug Monograph Content Contributors and Reviewers v
Preface vii
A Detailed Guide to Mosby’s Dental Drug Reference, Twelfth Edition vii
Table Of Contents ix
Internet References for Additional Drug Information and Professional Guidelines xi
Medication-Related Osteonecrosis of the Jaw xiii
Monoclonal Antibodies and Other Biologic Drugs xv
Summary: xv
Classification: xv
Dental Considerations for Monoclonal Antibodies/Biologically Targeted Agents xv
General: xv
Consultations: xvi
Teach Patient/Family to: xvi
Reference: xvi
abacavir 1
Category and Schedule 1
Drug Class: 1
Mechanism of Action 1
Uses 1
Pharmacokinetics 1
Indications and Dosages 1
► HIV Infection (in combination with other antiretrovirals) 1
PO 1
Adults. 1
Children (3 mo–16 yr). 1
► Dosage in Hepatic Impairment 1
Mild Impairment. 1
Moderate to Severe Impairment. 1
Side Effects/Adverse Reactions 1
Adults 1
abarelix 2
Category and Schedule 2
Drug Class: 2
Mechanism of Action 2
Uses 2
Pharmacokinetics 2
Indications and Dosages 2
► Prostate Cancer 2
IM 2
Adults, Elderly. 2
Side Effects/Adverse Reactions 2
Frequent 2
Occasional 2
Rare 2
Precautions and Contraindications 3
Drug Interactions of Concern to Dentistry 3
Serious Reactions 3
Dental Considerations 3
General: 3
Consultations: 3
Teach Patient/Family to: 3
abatacept 3
Category and Schedule 3
Drug Class: 3
Mechanism of Action 3
Uses 3
Pharmacokinetics 3
Indications and Dosages 3
► Rheumatoid Arthritis (moderate to severe) in patients who have had an inadequate response to one or more disease-modifying antirheumatic drugs 3
IV 4
Adults. 4
Children. 4
abciximab 5
Category and Schedule 5
Drug Class: 5
Mechanism of Action 5
Uses 5
Pharmacokinetics 5
Indications and Dosages 5
► Percutaneous Coronary Intervention (PCI) 5
absorbable gelatin sponge 6
Category and Schedule 6
Drug Class: 6
Mechanism of Action 6
Uses 6
Pharmacokinetics 6
Indications and Dosages 6
► Dental Use 6
Adult. 6
Side Effects/Adverse Reactions 6
acamprosate calcium 7
Category and Schedule 7
Drug Class: 7
Mechanism of Actions 7
Uses 7
Pharmacokinetics 7
Indications and Dosages 7
► Maintenance of Alcohol Abstinence 7
PO 7
Adult. 7
Side Effects/Adverse Reactions 7
Precautions and Contraindications 7
Caution: 7
Drug Interactions of Concern to Dentistry 7
Dental Considerations 7
Teach Patient/Family to: 7
General: 7
Consultations: 8
Teach Patient/Family to: 8
acarbose 8
Category and Schedule 8
Drug Class: 8
Mechanism of Action 8
Uses 8
Pharmacokinetics 8
acebutolol 9
Category and Schedule 9
Drug Class: 9
Mechanism of Action 9
Uses 9
Pharmacokinetics 9
Indications and Dosages 10
► Mild-to-Moderate Hypertension 10
acetaminophen 11
Category and Schedule 11
Drug Class: 11
Mechanism of Action 11
Uses 11
Pharmacokinetics 11
Indications and Dosages 12
► Analgesia and Antipyresis 12
PO 12
Adults, Elderly. 12
acetazolamide 13
Category and Schedule 13
Drug Class: 13
Mechanism of Action 13
Uses 13
Pharmacokinetics 13
Indications and Dosages 14
► Glaucoma 14
acetohexamide 15
Category and Schedule 15
Drug Class: 15
Mechanism of Action 15
Uses 15
Pharmacokinetics 15
Indications and Dosages 15
► Diabetes Mellitus 15
PO 15
Adults, Elderly. 15
Side Effects/Adverse Reactions 16
Frequent 16
Occasional 16
Precautions and Contraindications 16
Caution: 16
Drug Interactions of Concern to Dentistry 16
Serious Reactions 16
Dental Considerations 16
General: 16
Consultations: 16
Teach Patient/Family to: 16
acetylcholine chloride 17
Category and Schedule 17
Drug Class: 17
Mechanism of Action 17
Uses 17
Pharmacokinetics 17
Indications and Dosages 17
► Production of Miosis 17
Intraocular 17
Adults, Elderly. 17
Side Effects/Adverse Reactions 17
Rare 17
Precautions and Contraindications 17
Drug Interactions of Concern to Dentistry 17
Serious Reactions 17
Dental Considerations 17
General: 17
Uses 18
Pharmacokinetics 18
Indications and Dosages 18
► Adjunctive Treatment of Viscid Mucus Secretions from Chronic Bronchopulmonary Disease and for Pulmonary Complications of Cystic Fibrosis 18
Nebulization 18
acetylcysteine 17
acitretin 19
Category and Schedule 19
Drug Class: 19
Mechanism of Action 19
Uses 19
Pharmacokinetics 19
Indications and Dosages 19
► Psoriasis 19
PO 19
Adults, Elderly. 19
Side Effects/Adverse Reactions 20
Frequent 20
Occasional 20
Precautions and Contraindications 20
Caution: 20
Drug Interactions of Concern to Dentistry 20
Serious Reactions 20
Dental Considerations 20
General: 20
Consultations: 20
Teach Patient/Family to: 20
acyclovir 21
Category and Schedule 21
Drug Class: 21
Mechanism of Action 21
Uses 21
Pharmacokinetics 21
Indications and Dosages 21
► Genital Herpes (initial episode) 21
adalimumab 23
Category and Schedule 23
Drug Class: 23
Mechanism of Action 23
Uses 23
Pharmacokinetics 23
Indications and Dosages 23
► Rheumatoid Arthritis 23
Subcutaneous 23
Adults, Elderly. 23
Side Effects/Adverse Reactions 23
Frequent 23
Occasional 23
Rare 23
Precautions and Contraindications 23
Caution: 23
Drug Interactions of Concern to Dentistry 23
Serious Reactions 23
Dental Considerations 23
General: 23
Consultations: 24
Teach Patient/Family to: 24
adapalene 24
Category and Schedule 24
Drug Class: 24
Mechanism of Action 24
Uses 24
Pharmacokinetics 24
Indications and Dosages 24
► Acne Vulgaris 24
Topical 24
Adults, Elderly, Children older than 12 yr. 24
Side Effects/Adverse Reactions 24
Frequent 24
Occasional 24
Precautions and Contraindications 24
Drug Interactions of Concern to Dentistry 24
Serious Reactions 24
Dental Considerations 24
General: 24
Teach Patient/Family to: 25
adefovir 25
Category and Schedule 25
Drug Class: 25
Mechanism of Action 25
Uses 25
Pharmacokinetics 25
Indications and Dosages 25
► Chronic Hepatitis B in Patients with Normal Renal Function 25
aflibercept 26
Category and Schedule 26
Drug Class: 26
Mechanism of Action 26
Uses 26
Pharmacokinetics 26
Indications and Dosages 26
► Age-Related Macular Degeneration (AMD) 26
albendazole 27
Category and Schedule 27
Drug Class: 27
Mechanism of Action 27
Uses 27
Pharmacokinetics 27
Indications and Dosages 27
► Neurocysticercosis 27
PO 27
Adults, Elderly weighing more than 60 kg. 27
Adults, Elderly weighing less than 60 kg. 27
► Cystic Hydatid 28
PO 28
Adults, Elderly weighing more than 60 kg. 28
Side Effects/Adverse Reactions 28
Frequent 28
Occasional 28
Precautions and Contraindications 28
Drug Interactions of Concern to Dentistry 28
Serious Reactions 28
Dental Considerations 28
General: 28
Consultations: 28
albiglutide 28
Category and Schedule 28
Drug Class: 28
Mechanism of Action 28
Uses 28
Pharmacokinetics 28
Indications and Dosages 29
► Type 2 Diabetes Mellitus 29
Adults. 29
Side Effects/Adverse Reactions 29
Frequent 29
Occasional 29
Precautions and Contraindications 29
Drug Interactions of Concern to Dentistry 29
Serious Reactions 29
Dental Considerations 29
General: 29
Consultations: 29
Teach Patient/Family to: 30
albuterol 30
Category and Schedule 30
Drug Class: 30
Mechanism of Action 30
Uses 30
Pharmacokinetics 30
Indications and Dosages 30
► Bronchospasm 30
PO 30
alclometasone 31
Category and Schedule 31
Drug Class: 31
Mechanism of Action 32
Uses 32
Pharmacokinetics 32
Indications and Dosages 32
► Atopic Dermatitis, Contact Dermatitis, Dermatitis, Discoid Lupus Erythematosus, Eczema, Exfoliative Dermatitis, Granuloma Annulare, Lichen Planus, Lichen Simplex, Polymorphous Light Eruption, Pruritus, Psoriasis, Rhus Dermatitis, Seborrheic Dermatitis, Xerosis 32
Topical 32
Adults, Adolescents, Children 1 yr and older. 32
Side Effects/Adverse Reactions 32
Frequent 32
Occasional 32
Rare 32
Precautions and Contraindications 32
Drug Interactions of Concern to Dentistry 32
Serious Reactions 32
Dental Considerations 32
General: 32
Teach Patient/Family to: 32
interleukin-2 (aldesleukin) 32
Category and Schedule 32
Drug Class: 32
Mechanism of Action 33
Uses 33
Pharmacokinetics 33
Indications and Dosages 33
► Metastatic Melanoma, Metastatic Renal Cell Carcinoma 33
IV 33
Adults 18 yr and older. 33
Side Effects/Adverse Reactions 33
Frequent 33
Occasional 33
Rare 33
Precautions and Contraindications 33
Drug Interactions of Concern to Dentistry 33
Serious Reactions 33
Dental Considerations 34
General: 34
Consultations: 34
Teach Patient/Family to: 34
alefacept 34
Category and Schedule 34
Drug Class: 34
alemtuzumab 35
Category and Schedule 35
Drug Class: 35
Mechanism of Action 35
Uses 35
Pharmacokinetics 35
Indications and Dosages 35
► Plaque Psoriasis 35
IV 35
Uses 36
Pharmacokinetics 36
Indications and Dosages 36
► Chronic Lymphocytic Leukemia 36
IV 36
Adults, Elderly. 36
Side Effects/Adverse Reactions 36
Frequent 36
Occasional 36
Precautions and Contraindications 36
Drug Interactions of Concern to Dentistry 36
Serious Reactions 36
Dental Considerations 36
General: 36
Consultations: 37
Teach Patient/Family to: 37
alendronate sodium 37
Category and Schedule 37
Drug Class: 37
Mechanism of Action 37
Uses 37
Pharmacokinetics 37
Indications and Dosages 37
► Osteoporosis (in Men) 37
PO 37
Adults, Elderly. 37
► Glucocorticoid-Induced Osteoporosis 38
alfuzosin 39
Category and Schedule 39
Drug Class: 39
Mechanism of Action 39
Uses 39
Pharmacokinetics 39
Indications and Dosages 39
► Bph 39
PO 39
Adults. 39
Side Effects/Adverse Reactions 39
Frequent 39
Occasional 39
Rare 39
Precautions and Contraindications 39
Caution: 39
Drug Interactions of Concern to Dentistry 39
Serious Reactions 40
Dental Considerations 40
General: 40
Consultations: 40
Teach Patient/Family to: 40
alglucosidase alfa 40
Category and Schedule 40
Drug Class: 40
Mechanism of Action 40
Uses 40
Pharmacokinetics 40
Indications and Dosages 40
► Replacement Therapy for Pompe Disease 40
IV Infusion 40
Adults. 40
Children (1 mo–3.5 yr. at first infusion). 40
Side Effects/Adverse Reactions 40
Frequent 40
Precautions and Contraindications 41
Caution: 41
Drug Interactions of Concern to Dentistry 41
Serious Reactions 41
Dental Considerations 41
General: 41
Teach Patient/Family to: 41
aliskiren 41
Category and Schedule 41
Drug Class: 41
Mechanism of Action 41
Uses 41
Pharmacokinetics 41
Indications and Dosages 42
► Hypertension (Monotherapy) 42
Adults. 42
Side Effects/Adverse Reactions 42
Frequent 42
Occasional 42
Rare 42
Precautions and Contraindications 42
Drug Interactions of Concern to Dentistry 42
Serious Reactions 42
Dental Considerations 42
General: 42
Consultations: 42
Teach patient/family to: 42
alitretinoin 42
Category and Schedule 42
Drug Class: 42
Mechanism of Action 42
allopurinol 43
Category and Schedule 43
Drug Class: 43
Mechanism of Action 43
Uses 43
Pharmacokinetics 43
Indications and Dosages 43
► KS Skin Lesions 43
Topical 43
Adults. 43
Side Effects/Adverse Reactions 43
Frequent 43
Precautions and Contraindications 43
Caution: 43
Drug Interactions of Concern to Dentistry 43
Serious Reactions 43
Dental Considerations 43
General: 43
Pharmacokinetics 44
Indications and Dosages 44
► Chronic Gouty Arthritis 44
almotriptan malate 45
Category and Schedule 45
Drug Class: 45
Mechanism of Action 45
Uses 45
Pharmacokinetics 45
Indications and Dosages 45
► Migraine Headache 45
PO 45
Adults, Elderly. 45
► Dosage in Renal Impairment 45
Side Effects/Adverse Reactions 45
Frequent 45
Occasional 45
Precautions and Contraindications 45
Caution: 45
Drug Interactions of Concern to Dentistry 46
Serious Reactions 46
Dental Considerations 46
General: 46
Consultations: 46
Teach Patient/Family to: 46
alogliptin 46
Category and Schedule 46
Drug Class: 46
Mechanism of Action 46
Uses 46
Pharmacokinetics 46
Indications and Dosages 46
► Type 2 Diabetes Mellitus 46
PO 46
Adults. 46
Side Effects/Adverse Reactions 47
Frequent 47
Occasional 47
Precautions and Contraindications 47
Drug Interactions of Concern to Dentistry 47
Serious Reactions 47
Dental Considerations 47
General: 47
Consultations: 47
Teach Patient/Family to: 48
alprazolam 48
Category and Schedule 48
Drug Class: 48
Mechanism of Action 48
Uses 48
Pharmacokinetics 48
Indications and Dosages 48
► Anxiety Disorders 48
alprostadil (prostaglandin e1, pge1) 50
Category and Schedule 50
Mechanism of Action 50
Uses 50
Pharmacokinetics 50
Indications and Dosages 50
► Maintain Patency of Ductus Arteriosus 50
IV Infusion 50
Neonates. 50
► Impotence 50
Pellet, Intracavernosal 50
Adults. 50
Side Effects/Adverse Reactions 50
Frequent 50
Occasional 50
Precautions and Contraindications 50
Caution: 50
Drug Interactions of Concern to Dentistry 50
alvimopan 51
Category and Schedule 51
Drug Class: 51
Mechanism of Action 51
Uses 51
Pharmacokinetics 51
Indications and Dosages 51
► Postoperative Control of Ileus 51
Adult. 51
Side Effects/Adverse Reactions 51
Frequent 51
Occasional 51
Precautions and Contraindications 51
Drug Interactions of Concern to Dentistry 51
Serious Reactions 51
Dental Considerations 51
General: 51
Consultations: 51
Teach patient/family to: 51
amantadine hydrochloride 52
Category and Schedule 52
Drug Class: 52
Mechanism of Action 52
Uses 52
Pharmacokinetics 52
Indications and Dosages 52
► Prevention and Symptomatic Treatment of Respiratory Illness Caused by Influenza A Virus 52
ambenonium 53
Category and Schedule 53
Drug Class: 53
Mechanism of Action 53
Uses 53
Pharmacokinetics 53
Indications and Dosages 53
► Myasthenia Gravis 53
PO 53
Adults. 53
Side Effects/Adverse Reactions 53
Frequent 53
Occasional 53
Rare 54
Precautions and Contraindications 54
Caution: 54
Drug Interactions of Concern to Dentistry 54
Serious Reactions 54
Dental Considerations 54
General: 54
Consultations: 54
Teach Patient/Family to: 54
ambrisentan 54
Category and Schedule 54
Drug Class: 54
amcinonide 55
Category and Schedule 55
Drug Class: 55
Mechanism of Action 55
Uses 55
Pharmacokinetics 55
Indications and Dosages 55
► Pulmonary Arterial Hypertension 55
Adult. 55
Side Effects/Adverse Reactions 55
Frequent 55
Occasional 55
Precautions and Contraindications 55
Drug Interactions of Concern to Dentistry 55
Serious Reactions 55
Dental Considerations 55
General: 55
Consultations: 55
Teach patient/family to: 55
Uses 56
Pharmacokinetics 56
Indications and Dosages 56
► Dermatoses 56
Topical 56
Adults, Elderly. 56
Side Effects/Adverse Reactions 56
Frequent 56
Occasional 56
Rare 56
Precautions and Contraindications 56
Drug Interactions of Concern to Dentistry 56
Serious Reactions 56
Dental Considerations 56
General: 56
Teach Patient/Family to: 56
amifostine 56
Category and Schedule 56
Drug Class: 56
Mechanism of Action 56
Uses 57
Pharmacokinetics 57
Indications and Dosages 57
► To Reduce Cumulative Renal Toxicity from Repeated Administration of Cisplatin in Patients with Advanced Ovarian Cancer 57
amiloride hydrochloride 58
Category and Schedule 58
Drug Class: 58
Mechanism of Action 58
Uses 59
Pharmacokinetics 59
Indications and Dosages 59
► To Counteract Potassium Loss Induced by Other Diuretics 59
PO 59
Adults, Children weighing more than 20 kg. 59
Elderly. 59
Children weighing 6–20 kg. 59
► Dosage in Renal Impairment 59
Side Effects/Adverse Reactions 59
Frequent 59
Occasional 59
Rare 59
Precautions and Contraindications 59
Caution: 59
Drug Interactions of Concern to Dentistry 59
Serious Reactions 59
Dental Considerations 59
General: 59
Consultations: 60
Teach Patient/Family to: 60
aminoglutethimide 60
Category and Schedule 60
Drug Class: 60
Mechanism of Action 60
Uses 60
Pharmacokinetics 60
Indications and Dosages 60
► Cushing’s Syndrome 60
PO 60
Adults. 60
Side Effects/Adverse Reactions 60
Frequent 60
Occasional 60
Rare 60
Precautions and Contraindications 60
Drug Interactions of Concern to Dentistry 60
Serious Reactions 60
Dental Considerations 61
General: 61
Consultations: 61
Teach Patient/Family to: 61
aminophylline/theophylline 61
Category and Schedule 61
Drug Class: 61
Mechanism of Action 62
Uses 62
Pharmacokinetics 62
Indications and Dosages 62
► Chronic Bronchospasm 62
aminosalicylic acid 63
Category and Schedule 63
Drug Class: 63
Mechanism of Action 63
Uses 63
Pharmacokinetics 63
Indications and Dosages 64
► Tuberculosis 64
PO 64
Adults, Elderly. 64
Children. 64
Side Effects/Adverse Reactions 64
Occasional 64
Rare 64
Precautions and Contraindications 64
Caution: 64
Drug Interactions of Concern to Dentistry 64
Serious Reactions 64
Dental Considerations 64
General: 64
Consultations: 64
Teach Patient/Family to: 64
amiodarone hydrochloride 65
Category and Schedule 65
Drug Class: 65
Mechanism of Action 65
Uses 65
Pharmacokinetics 65
Indications and Dosages 65
► Life-Threatening Recurrent Ventricular Fibrillation or Hemodynamically Unstable Ventricular Tachycardia 65
PO 65
Adults, Elderly. 65
Children. 65
IV Infusion 65
Adults. 65
Side Effects/Adverse Reactions 65
Expected 65
Frequent 65
Occasional 65
Rare 66
Precautions and Contraindications 66
Caution: 66
Drug Interactions of Concern to Dentistry 66
Serious Reactions 66
Dental Considerations 66
General: 66
Consultations: 66
Teach Patient/Family to: 66
amitriptyline hydrochloride 67
Category and Schedule 67
Drug Class: 67
Mechanism of Action 67
Uses 67
Pharmacokinetics 67
Indications and Dosages 67
► Depression 67
amlexanox 69
Category and Schedule 69
Drug Class: 69
Mechanism of Action 69
Uses 69
Pharmacokinetics 69
Indications and Dosages 69
► Aphthous Ulcers 69
Topical 69
Adults, Elderly. 69
Side Effects/Adverse Reactions 69
Rare 69
Precautions and Contraindications 69
Caution: 69
Drug Interactions of Concern to Dentistry 69
Serious Reactions 69
Dental Considerations 69
General: 69
Teach Patient/Family to: 69
Uses 70
Pharmacokinetics 70
Indications and Dosages 70
► Essential Hypertension, Stable Angina and Vasospastic Angina 70
Adult. 70
Child (6–17 yr). 70
Side effects/adverse reactions 70
Frequent 70
Occasional 70
Rare 70
Precautions and Contraindications 70
Drug Interactions of Concern to Dentistry 70
Serious Reactions 70
Dental Considerations 70
General: 70
Consultations: 71
Teach Patient/Family to: 71
amlodipine 69
amoxapine 71
Category and Schedule 71
Drug Class: 71
Mechanism of Action 71
Uses 71
Pharmacokinetics 71
Indications and Dosages 71
► Depression 71
PO 71
Adults. 71
Adolescents. 71
Elderly. 71
Side Effects/Adverse Reactions 71
Frequent 71
Occasional 71
Rare 71
Precautions and Contraindications 72
Caution: 72
Drug Interactions of Concern to Dentistry 72
Serious Reactions 72
Dental Considerations 72
General: 72
Consultations: 72
Teach Patient/Family to: 72
amoxicillin 73
Category and Schedule 73
Drug Class: 73
Mechanism of Action 73
Uses 73
Pharmacokinetics 73
Indications and Dosages 73
► Ear, Nose, and Throat Infections 73
amoxicillin/clavulanate potassium 74
Category and Schedule 74
Drug Class: 74
Mechanism of Action 75
Uses 75
Pharmacokinetics 75
Indications and Dosages 75
► Mild-to-Moderate Infections 75
amphetamine 76
Category and Schedule 76
Drug Class: 76
Mechanism of Action 76
Uses 76
Pharmacokinetics 76
Indications and Dosages 76
► Adhd 76
PO 76
Adults. 76
Adults, Children older than 12 yr. 76
Children 6–12 yr. 76
Children 3–6 yr. 77
► Narcolepsy 77
PO 77
Adults. 77
Adults, Children older than 12 yr. 77
Children 6–12 yr. 77
Side Effects/Adverse Reactions 77
Frequent 77
Occasional 77
Precautions and Contraindications 77
Caution: 77
Drug Interactions of Concern to Dentistry 77
Serious Reactions 77
Dental Considerations 77
General: 77
Consultations: 77
Teach Patient/Family to: 77
amphotericin b 78
Category and Schedule 78
Drug Class: 78
Mechanism of Action 78
Uses 78
Pharmacokinetics 78
Indications and Dosages 78
► Cryptococcosis; Blastomycosis; Systemic Candidiasis; Disseminated Forms of Moniliasis, Coccidioidomycosis, and Histoplasmosis; Zygomycosis; Sporotrichosis; Aspergillosis 78
IV Infusion (Fungizone) 78
Adults, Elderly. 78
Children. 78
► Invasive Fungal Infections Unresponsive to or Intolerant of Fungizone 78
IV Infusion (Abelcet) 78
Adults, Children. 78
► Empiric Treatment of Fungal Infections in Patients with Febrile Neutropenia; Aspergillosis, Candidiasis, or Cryptococcosis in Patients with Renal Impairment and Those Who Have Experienced Toxicity or Treatment Failure with Fungizone 78
IV Infusion (Ambisome) 78
amphotericin b, lipid-based 79
Category and Schedule 79
Drug Class: 79
Mechanism of Action 80
Uses 80
Pharmacokinetics 80
Indications and Dosages 80
► Invasive Fungal Infections Unresponsive to, or Intolerant of, Fungizone. 80
IV Infusion 80
Adults, Children. 80
Side Effects/Adverse Reactions 80
Frequent 80
Occasional 80
Precautions and Contraindications 80
Drug Interactions of Concern to Dentistry 80
Serious Reactions 80
Dental Considerations 80
General: 80
Consultations: 80
Teach Patient/Family to: 81
ampicillin 81
Category and Schedule 81
Drug Class: 81
Mechanism of Action 81
Uses 81
Pharmacokinetics 81
Indications and Dosages 81
► Respiratory Tract, Skin/Skin-Structure Infections 81
ampicillin sodium 82
Category and Schedule 82
Drug Class: 82
Mechanism of Action 83
Uses 83
Pharmacokinetics 83
Indications and Dosages 83
► Respiratory Tract, Skin and Skin-Structure Infections 83
ampicillin/sulbactam sodium 84
Category and Schedule 84
Drug Class: 84
Mechanism of Action 84
Uses 84
Pharmacokinetics 84
Indications and Dosages 84
► Skin and Skin-Structure, Intraabdominal, and Gynecologic Infections 84
IV, IM 84
Adults, Elderly. 84
► Dosage in Renal Impairment 84
Side Effects/Adverse Reactions 84
Frequent 84
Occasional 85
Precautions and Contraindications 85
Drug Interactions of Concern to Dentistry 85
Serious Reactions 85
Dental Considerations 85
General: 85
Consultations: 85
Teach Patient/Family to: 85
amprenavir 85
Category and Schedule 85
Drug Class: 85
Mechanism of Action 85
Uses 86
Pharmacokinetics 86
Indications and Dosages 86
► HIV-1 Infection (in combination with other antiretrovirals) 86
PO 86
Adults, Children 13–16 yr. 86
amyl nitrite 87
Category and Schedule 87
Drug Class: 87
Mechanism of Action 87
Uses 87
Pharmacokinetics 87
Indications and Dosages 87
► Acute Relief of Angina Pectoris 87
Nasal Inhalation 87
Adults, Elderly. 87
Side Effects/Adverse Reactions 87
Frequent 87
Occasional 88
Rare 88
Precautions and Contraindications 88
Drug Interactions of Concern to Dentistry 88
Serious Reactions 88
Dental Considerations 88
General: 88
Consultations: 88
Teach Patient/Family to: 88
anagrelide 88
Category and Schedule 88
Drug Class: 88
Mechanism of Action 88
Uses 89
Pharmacokinetics 89
Indications and Dosages 89
► Thrombocythemia 89
PO 89
Adults, Elderly. 89
Side Effects/Adverse Reactions 89
Frequent 89
Occasional 89
Rare 89
Precautions and Contraindications 89
Caution: 89
Drug Interactions of Concern to Dentistry 89
Serious Reactions 89
Dental Considerations 89
General: 89
Consultations: 89
Teach Patient/Family to: 89
anakinra 90
Category and Schedule 90
Drug Class: 90
Mechanism of Action 90
Uses 90
Pharmacokinetics 90
Indications and Dosages 90
► Rheumatoid Arthritis 90
Subcutaneous 90
Adults, Children older than 18 yr, Elderly. 90
Side Effects/Adverse Reactions 90
Occasional 90
Rare 90
Precautions and Contraindications 90
Drug Interactions of Concern to Dentistry 90
Serious Reactions 90
Dental Considerations 90
General: 90
Consultations: 90
Teach Patient/Family to: 91
anastrozole 91
Category and Schedule 91
Drug Class: 91
Mechanism of Action 91
Uses 91
Pharmacokinetics 91
Indications and Dosages 91
► Breast Cancer 91
PO 91
Adults, Elderly. 91
Side Effects/Adverse Reactions 91
Frequent 91
Occasional 91
Rare 91
Precautions and Contraindications 91
Drug Interactions of Concern to Dentistry 91
Serious Reactions 91
Dental Considerations 91
General: 91
Consultations: 92
Teach Patient/Family to: 92
anidulafungin 92
Category and Schedule 92
Drug Class: 92
Mechanism of Action 92
Uses 92
Pharmacokinetics 92
Indications and Dosages 92
► Candidemia 92
IV 92
Adults. 92
► Esophageal Candidiasis 93
IV 93
Adult. 93
Children. 93
Side Effects/Adverse Reactions 93
Rare 93
Precautions and Contraindications 93
Caution: 93
Drug Interactions of Concern to Dentistry 93
Serious Reactions 93
Dental Considerations 93
General: 93
Teach Patient/Family to: 93
apomorphine 93
Category and Schedule 93
Drug Class: 93
Mechanism of Action 93
Uses 93
Pharmacokinetics 93
Indications and Dosages 94
► Acute, Intermittent Treatment of Hypomobility (“Off Episodes”) Associated with Advanced Parkinson’s Disease 94
Injection Pen for Subcutaneous Administration 94
Adult, Elderly. 94
Side Effects/Adverse Reactions 94
Precautions and Contraindications 94
Drug Interactions of Concern to Dentistry 94
Dental Considerations 94
General: 94
Consultations: 94
Teach Patient/Family to: 94
apraclonidine hydrochloride 95
Category and Schedule 95
Drug Class: 95
Mechanism of Action 95
Uses 95
Pharmacokinetics 95
Indications and Dosages 95
► Glaucoma 95
apremilast 96
Category and Schedule 96
Drug Class: 96
Mechanism of Action 96
Uses 96
Pharmacokinetics 96
Indications and Dosages 96
► Active Psoriatic Arthritis or Plaque Psoriasis (Moderate to Severe) 96
PO 96
Adults. 96
Side Effects/Adverse Reactions 96
Frequent 96
Occasional 96
Precautions and Contraindications 96
Drug Interactions of Concern to Dentistry 97
Serious Reactions 97
Dental Considerations 97
General: 97
Teach Patient/Family to: 97
aprepitant 97
Category and Schedule 97
Drug Class: 97
Mechanism of Action 97
Uses 97
Pharmacokinetics 97
Indications and Dosages 97
► Prevention of Chemotherapy-Induced Nausea and Vomiting 97
PO 97
Adults, Elderly. 97
Side Effects/Adverse Reactions 97
Frequent 97
Occasional 97
Rare 97
Precautions and Contraindications 98
Caution: 98
Drug Interactions of Concern to Dentistry 98
Serious Reactions 98
Dental Considerations 98
General: 98
Consultations: 98
Teach Patient/Family to: 98
arformoterol tartrate 99
Category and Schedule 99
Drug Class: 99
Mechanism of Action 99
Uses 99
Pharmacokinetics 99
Indications and Dosages 99
► COPD 99
Oral Inhalation 99
Adults. 99
Children. 99
Side Effects/Adverse Reactions 99
Occasional 99
Rare 99
Precautions and Contraindications 99
Caution: 99
Drug Interactions of Concern to Dentistry 99
Serious Reactions 99
Dental Considerations 99
General: 99
Consultations: 100
Teach Patient/Family to: 100
aripiprazole 100
Category and Schedule 100
Drug Class: 100
Mechanism of Action 100
Uses 100
Pharmacokinetics 100
Indications and Dosages 100
► Schizophrenia, Bipolar Disorder 100
PO 100
Adults, Elderly. 100
Side Effects/Adverse Reactions 100
Frequent 100
Occasional 100
Rare 100
Precautions and Contraindications 100
Caution: 100
Drug Interactions of Concern to Dentistry 100
Serious Reactions 101
Dental Considerations 101
General: 101
Consultations: 101
Teach Patient/Family to: 101
armodafinil 101
Category and Schedule 101
Drug Class: 101
Mechanism of Action 101
Uses 101
Pharmacokinetics 101
Indications and Dosages 101
► Narcolepsy, Improve Wakefulness in Patients with Excessive Sleepiness; Obstructive Sleep Apnea 101
artemether/lumefantrine 102
Category and Schedule 102
Drug Class: 102
Mechanism of Action 102
Uses 103
Pharmacokinetics 103
Indications and Dosages 103
► Malaria due to Plasmodium falciparum 103
PO 103
Adults, 16 yr and older (who weigh 35 kg or greater). 103
Children younger than 16 yr old who weigh 25 to less than 35 kg. 103
Children younger than 16 yr old who weigh 15 to less than 25 kg. 103
Children younger than 16 yr old who weigh 5 to less than 15 kg. 103
Side Effects/Adverse Reactions 103
Frequent 103
Occasional 103
Rare 103
Precautions and Contraindications 103
Caution: 103
Drug Interactions of Concern to Dentistry 104
Serious Reactions 104
Dental Considerations 104
General: 104
Consultations: 104
Teach Patient/Family to: 104
articaine hydrochloride 105
Category and Schedule 105
Drug Class: 105
Mechanism of Action 105
Uses 105
Pharmacokinetics 105
Indications and Dosages 105
► Local, Infiltrative, or Conductive Anesthesia in Both Simple and Complex Dental or Periodontal Procedures 105
Infiltration 105
Adults, Elderly, Children older than 4 yr. 105
Side Effects/Adverse Reactions 105
Rare 105
Precautions and Contraindications 105
Caution: 105
Drug Interactions of Concern to Dentistry 105
Serious Reactions 106
Dental Considerations 106
General: 106
Teach Patient/Family to: 106
asenapine 106
Category and Schedule 106
Drug Class: 106
Mechanism of Action 106
Uses 106
Pharmacokinetics 106
Indications and Dosages 107
► Schizophrenia 107
aspirin/acetylsalicylic acid 108
Category and Schedule 108
Drug Class: 108
Mechanism of Action 108
Uses 108
Pharmacokinetics 108
Indications and Dosages 108
► Analgesia, Fever 108
PO, Rectal 108
atazanavir + cobicistat 110
Category and Schedule 110
Drug Class: 110
Mechanism of Action 110
Uses 110
Pharmacokinetics 110
Indications and Dosages 111
► HIV-1 Infection (treatment-naive or treatment-experienced) 111
PO 111
Adults. 111
Side Effects/Adverse Reactions 111
Frequent 111
Occasional 111
Precautions and Contraindications 111
Drug Interactions of Concern to Dentistry 111
Serious Reactions 111
Dental Considerations 112
General: 112
Consultations: 112
Teach Patient/Family to: 112
atazanavir sulfate 112
Category and Schedule 112
Drug Class: 112
Mechanism of Action 112
Uses 112
Pharmacokinetics 112
Indications and Dosages 112
► HIV-1 Infection 112
atenolol 114
Category and Schedule 114
Drug Class: 114
Mechanism of Action 114
Uses 114
Pharmacokinetics 114
Indications and Dosages 114
► Hypertension 114
atomoxetine 116
Category and Schedule 116
Drug Class: 116
Mechanism of Action 116
Uses 116
Pharmacokinetics 116
Indications and Dosages 116
► ADHD 116
PO 116
Adults, Children weighing 70 kg and more. 116
Children weighing less than 70 kg. 116
► Dosage in Hepatic Impairment 116
Side Effects/Adverse Reactions 116
Frequent 116
Occasional 116
Rare 117
Precautions and Contraindications 117
Caution: 117
Drug Interactions of Concern to Dentistry 117
Serious Reactions 117
Dental Considerations 117
General: 117
Consultations: 117
Teach Patient/Family to: 117
atorvastatin 117
Category and Schedule 117
Drug Class: 117
Mechanism of Action 117
Uses 118
Pharmacokinetics 118
Indications and Dosages 118
► Hyperlipidemia, Reduction of Risk of MI, Angina Revascularization Procedures 118
atropine sulfate 118
Category and Schedule 118
Drug Class: 118
Mechanism of Action 119
Uses 119
Pharmacokinetics 119
Indications and Dosages 119
► Asystole, Slow, Pulseless Electrical Activity 119
aurothioglucose/gold sodium thiomalate 120
Category and Schedule 120
Drug Class: 120
Mechanism of Action 120
Uses 120
Pharmacokinetics 120
Indications and Dosages 121
► Rheumatoid Arthritis (Aurothioglucose) 121
avanafil 122
Category and Schedule 122
Drug Class: 122
Mechanism of Action 122
Uses 122
Pharmacokinetics 122
Indications and Dosages 122
► Erectile Dysfunction 122
PO 122
Adults. 122
Side Effects/Adverse Reactions 123
Frequent 123
Occasional 123
Precautions and Contraindications 123
Drug Interactions of Concern to Dentistry 123
Serious Reactions 123
Dental Considerations 123
General: 123
Teach Patient/Family to: 123
axitinib 123
Category and Schedule 123
Drug Class: 123
Mechanism of Action 123
Uses 123
Pharmacokinetics 123
Indications and Dosages 124
► Renal Cell Cancer, Advanced 124
PO 124
Adults. 124
Side Effects/Adverse Reactions 124
Frequent 124
Occasional 124
Precautions and Contraindications 124
Drug Interactions of Concern to Dentistry 124
Serious Reactions 124
Dental Considerations 124
General: 124
Consultations: 124
Teach Patient/Family to: 125
azatadine maleate 125
Category and Schedule 125
Drug Class: 125
Mechanism of Action 125
Uses 125
Pharmacokinetics 125
Indications and Dosages 125
► Allergic Rhinitis 125
PO 125
Adults, Elderly, Children 12 yr or older. 125
Side Effects/Adverse Reactions 125
Frequent 125
Rare 125
Precautions and Contraindications 125
Drug Interactions of Concern to Dentistry 125
Serious Reactions 125
Dental Considerations 125
General: 125
Consultations: 126
Teach Patient/Family to: 126
azathioprine 126
Category and Schedule 126
Drug Class: 126
Mechanism of Action 126
Uses 126
Pharmacokinetics 126
Indications and Dosages 126
► Adjunct in Prevention of Renal Allograft Rejection 126
PO, IV 126
Adults, Elderly, Children. 126
► Rheumatoid Arthritis 126
PO 126
Adults. 126
Elderly. 127
► Dosage in Renal Impairment 127
Side Effects/Adverse Reactions 127
Frequent 127
Occasional 127
Rare 127
Precautions and Contraindications 127
Drug Interactions of Concern to Dentistry 127
Serious Reactions 127
Dental Considerations 127
General: 127
Consultations: 127
Teach Patient/Family to: 127
azelastine 127
Category and Schedule 127
Drug Class: 127
Mechanism of Action 128
Uses 128
Pharmacokinetics 128
Indications and Dosages 128
► Allergic Rhinitis 128
Nasal 128
Adults, Elderly, Children 12 yr and older. 128
Children 5–11 yr. 128
► Allergic Conjunctivitis 128
Ophthalmic 128
Adults, Elderly, Children 3 yr or older. 128
Side Effects/Adverse Reactions 128
Frequent 128
Rare 128
Precautions and Contraindications 128
Drug Interactions of Concern to Dentistry 128
Serious Reactions 128
Dental Considerations 128
General: 128
Teach Patient/Family: 128
azilsartan medoxomil 129
Category and Schedule 129
Drug Class: 129
Mechanism of Action 129
Uses 129
Pharmacokinetics 129
Indications and Dosages 129
► Hypertension 129
PO 129
Adults. 129
Side Effects/Adverse Reactions 129
Frequent 129
Occasional 129
Precautions and Contraindications 129
Drug Interactions of Concern to Dentistry 129
Serious Reactions 129
Dental Considerations 130
General: 130
Consultations: 130
Teach Patient/Family to: 130
azithromycin 130
Category and Schedule 130
Drug Class: 130
Mechanism of Action 130
Uses 130
Pharmacokinetics 130
Indications and Dosages 131
► Respiratory Tract, Skin, and Skin-Structure Infections 131
aztreonam 132
Category and Schedule 132
Drug Class: 132
Mechanism of Action 132
Uses 132
Pharmacokinetics 132
Indications and Dosages 132
► UTIs 132
bacitracin 134
Category and Schedule 134
Drug Class: 134
Mechanism of Action 134
Uses 134
Indications and Dosages 134
► Superficial Ocular Infections 134
Ophthalmic 134
Adults. 134
► Skin Abrasions, Superficial Skin Infections 134
Topical 134
Adults, Children. 134
► Surgical Treatment and Prophylaxis 134
Irrigation 134
Adults, Elderly. 134
Side Effects/Adverse Reactions 134
Rare 134
Precautions and Contraindications 134
Drug Interactions of Concern to Dentistry 134
Serious Reactions 134
Dental Considerations 134
General: 134
Teach Patient/Family to: 134
Mechanism of Action 135
Uses 135
Pharmacokinetics 135
Indications and Dosages 135
► Spasticity 135
PO 135
Adults. 135
Elderly. 135
Children. 135
Usual Intrathecal Dosage 135
Adults, Elderly, Children older than 12 yr. 135
Children 12 yr and younger. 135
Side Effects/Adverse Reactions 135
Frequent 135
Occasional 135
Rare 135
Precautions and Contraindications 135
Drug Interactions of Concern To Dentistry 135
Serious Reactions 135
Dental Considerations 135
General: 135
Teach Patient/Family: 136
baclofen 134
balsalazide 136
Category and Schedule 136
Drug Class: 136
Mechanism of Action 136
Uses 136
Pharmacokinetics 136
Indications and Dosages 136
► Ulcerative Colitis 136
PO 136
Adults, Elderly. 136
Side Effects/Adverse Reactions 136
Frequent 136
Occasional 136
Precautions and Contraindications 136
Drug Interactions of Concern to Dentistry 136
Serious Reactions 136
Dental Considerations 136
General: 136
Consultations: 136
becaplermin 137
Category and Schedule 137
Drug Class: 137
Mechanism of Action 137
Uses 137
Pharmacokinetics 137
Indications and Dosages 137
► Ulcers 137
Topical 137
Adults, Elderly. 137
Side Effects/Adverse Reactions 137
Occasional 137
Precautions and Contraindications 137
Caution: 137
Drug Interactions of Concern to Dentistry 137
Serious Reactions 137
Dental Considerations 137
General: 137
Consultations: 137
Teach Patient/Family to: 137
beclomethasone dipropionate/beclomethasone dipropionate hfa 138
Category and Schedule 138
Drug Class: 138
Mechanism of Action 138
Uses 138
Pharmacokinetics 138
Indications and Dosages 138
Oral Inhalation (QVAR only) 138
Adults, Adolescents. 138
Children 5–11 yr. 138
Nasal Inhalation 138
benazepril 139
Category and Schedule 139
Drug Class: 139
Mechanism of Action 139
Uses 139
Pharmacokinetics 139
Indications and Dosages 139
► Hypertension (monotherapy) 139
PO 139
Adults. 139
Elderly. 140
► Hypertension (combination therapy) 140
PO 140
Adults. 140
► Dosage in Renal Impairment 140
Side Effects/Adverse Reactions 140
Frequent 140
Occasional 140
Rare 140
Precautions and Contraindications 140
Caution: 140
Drug Interactions of Concern to Dentistry 140
Serious Reactions 140
Dental Considerations 140
General: 140
Consultations: 141
Teach Patient/Family to: 141
bendamustine 141
Category and Schedule 141
Drug Class: 141
Mechanism of Action 141
Uses 141
Pharmacokinetics 141
Indications and Dosages 141
IV 141
Adult. 141
Pediatric Dosing. 141
Dose Adjustments. 141
Side Effects/Adverse Reactions 142
Frequent 142
Occasional 142
Precautions and Contraindications 142
Drug Interactions of Concern to Dentistry 142
Serious Reactions 142
Dental Considerations 142
General: 142
Consultations: 142
Teach Patient/Family to: 142
bendroflumethiazide 143
Category and Schedule 143
Drug Class: 143
Mechanism of Action 143
Uses 143
Pharmacokinetics 143
Indications and Dosages 143
► Edema 143
benzocaine 144
Category and Schedule 144
Drug Class: 144
Mechanism of Action 145
Uses 145
Pharmacokinetics 145
Indications and Dosages 145
► Canker Sores 145
benzonatate 146
Category and Schedule 146
Drug Class: 146
Mechanism of Action 146
Uses 146
Pharmacokinetics 146
Indications and Dosages 146
► Antitussive 146
PO 146
Adults, Elderly, Children older than 10 yr. 146
Side Effects/Adverse Reactions 146
Occasional 146
Precautions and Contraindications 146
Caution: 146
Drug Interactions of Concern to Dentistry 146
Serious Reactions 146
Dental Considerations 146
General: 146
Uses 147
Pharmacokinetics 147
Indications and Dosages 147
► Edema 147
benzthiazide 146
benztropine mesylate 148
Category and Schedule 148
Drug Class: 148
Mechanism of Action 148
Uses 148
Pharmacokinetics 148
Indications and Dosages 148
► Parkinsonism 148
PO 148
bepridil 149
Category and Schedule 149
Drug Class: 149
Mechanism of Action 150
Uses 150
Pharmacokinetics 150
Indications and Dosages 150
► Chronic Stable Angina 150
PO 150
Adults, Elderly. 150
Side Effects/Adverse Reactions 150
Frequent 150
Occasional 150
Rare 150
Precautions and Contraindications 150
Caution: 150
Drug Interactions of Concern to Dentistry 150
Serious Reactions 150
Dental Considerations 150
General: 150
Consultations: 151
Teach Patient/Family to: 151
besifloxacin 151
Category and Schedule 151
Drug Class: 151
Mechanism of Action 151
Uses 151
Pharmacokinetics 151
Indications and Dosages 151
► Conjunctivitis 151
Adults, Children over 1 yr. 151
Side Effects/Adverse Reactions 151
Frequent 151
Occasional 151
Precautions and Contraindications 151
Drug Interactions of Concern to Dentistry 151
Serious Reactions 151
Dental Considerations 151
General: 151
betamethasone 152
Category and Schedule 152
Drug Class: 152
Mechanism of Action 152
Uses 152
Pharmacokinetics 152
Indications and Dosages 152
► Antiinflammation, Immunosuppression, Corticosteroid Replacement Therapy 152
PO 152
betaxolol 153
Category and Schedule 153
Drug Class: 153
Mechanism of Action 153
Uses 153
Pharmacokinetics 153
Indications and Dosages 153
► Hypertension 153
PO 153
Adults. 153
Elderly. 153
► Chronic Open-Angle Glaucoma and Ocular Hypertension 153
Ophthalmic (Eye Drops) 153
Adults, Elderly. 153
► Dosage in Renal Impairment 154
Side Effects/Adverse Reactions 154
Frequent 154
Occasional 154
Rare 154
Precautions and Contraindications 154
Caution: 154
Drug Interactions of Concern to Dentistry 154
Serious Reactions 154
Dental Considerations 154
General: 154
Consultations: 155
Teach Patient/Family to: 155
bethanechol chloride 155
Category and Schedule 155
Drug Class: 155
Mechanism of Action 155
Uses 155
Pharmacokinetics 155
Indications and Dosages 155
► Postoperative and Postpartum Urine Retention, Atony of Bladder 155
PO 155
Adults, Elderly. 155
Children. 155
Side Effects/Adverse Reactions 155
Occasional 155
Precautions and Contraindications 155
Caution: 156
Drug Interactions of Concern to Dentistry 156
Serious Reactions 156
Dental Considerations 156
General: 156
Consultations: 156
bevacizumab 156
Category and Schedule 156
Drug Class: 156
Mechanism of Action 156
Uses 156
Pharmacokinetics 156
Indications and Dosages 156
► First-Line Treatment of Metastatic Carcinoma of the Colon or Rectum in Combination with 5-Fluorouracil (5-FU) 156
IV 156
Adults, Elderly. 156
Side Effects/Adverse Reactions 156
Frequent 156
Occasional 156
Rare 156
Precautions and Contraindications 156
Drug Interactions of Concern to Dentistry 157
Serious Reactions 157
Dental Considerations 157
General: 157
Consultations: 157
Teach Patient/Family to: 157
bexarotene 158
Category and Schedule 158
Drug Class: 158
Mechanism of Action 158
Uses 158
Pharmacokinetics 158
Indications and Dosages 158
► Cutaneous T-Cell Lymphoma Refractory to at Least One Prior Systemic Therapy 158
PO 158
bicalutamide 159
Category and Schedule 159
Drug Class: 159
Mechanism of Action 159
Uses 159
Pharmacokinetics 159
Indications and Dosages 159
► Prostatic Carcinoma 159
PO 159
Adults, Elderly. 159
Side Effects/Adverse Reactions 159
Frequent 159
Occasional 159
Rare 159
Precautions and Contraindications 159
Caution: 159
Drug Interactions of Concern to Dentistry 159
Serious Reactions 159
Dental Considerations 159
General: 159
Consultations: 160
Teach Patient/Family to: 160
bimatoprost 160
Category and Schedule 160
Drug Class: 160
Mechanism of Action 160
Uses 160
Pharmacokinetics 160
Indications and Dosages 160
► Glaucoma, Ocular Hypertension 160
Ophthalmic 160
Adults, Elderly. 160
Side Effects/Adverse Reactions 160
Frequent 160
Occasional 160
Rare 160
Precautions and Contraindications 161
Caution: 161
Drug Interactions of Concern to Dentistry 161
Serious Reactions 161
Dental Considerations 161
General: 161
Consultations: 161
Teach Patient/Family to: 161
biperiden 161
Category and Schedule 161
Drug Class: 161
Mechanism of Action 161
Uses 161
Pharmacokinetics 161
Indications and Dosages 161
► Extrapyramidal Symptoms 161
bismuth subsalicylate 162
Category and Schedule 162
Drug Class: 162
Mechanism of Action 162
Uses 163
Pharmacokinetics 163
Indications and Dosages 163
► Diarrhea, Gastric Distress 163
bisoprolol fumarate 163
Category and Schedule 163
Drug Class: 163
Mechanism of Action 163
Uses 164
Pharmacokinetics 164
Indications and Dosages 164
► Hypertension 164
PO 164
Adults. 164
Elderly. 164
► Dosage in Hepatic Impairment 164
Side Effects/Adverse Reactions 164
Frequent 164
Occasional 164
Rare 164
Precautions and Contraindications 164
Caution: 164
Drug Interactions of Concern to Dentistry 164
Serious Reactions 164
Dental Considerations 164
General: 164
Consultations: 165
Teach Patient/Family to: 165
bivalirudin 165
Category and Schedule 165
Drug Class: 165
Mechanism of Action 165
Uses 165
Pharmacokinetics 165
Indications and Dosages 165
► Anticoagulant in Patients with Unstable Angina Who Are Undergoing Percutaneous Transluminal Coronary Angioplasty (PTCA) in Conjunction with Aspirin 165
IV 165
Adults, Elderly. 165
Dosage in Renal Impairment 166
Side Effects/Adverse Reactions 166
Frequent 166
Occasional 166
Rare 166
Precautions and Contraindications 166
Drug Interactions of Concern To Dentistry 166
Serious Reactions 166
Dental Considerations 166
General: 166
Consultations: 166
Teach Patient/Family to: 166
bleomycin sulfate 166
Category and Schedule 166
Drug Class: 166
Mechanism of Action 166
Uses 167
Pharmacokinetics 167
Indications and Dosages 167
► As Monotherapy to Treat Testicular Carcinoma; Lymphomas (Including Hodgkin’s Disease, Choriocarcinoma, Reticulum Cell Sarcoma, and Lymphosarcoma); and Squamous Cell Carcinomas of the Head and Neck (Including Mouth, Tongue, Tonsil, Nasopharynx, Oropharynx, Sinus, Palate, Lip, Buccal Mucosa, Gingiva, Epiglottis, and Larynx) 167
IV, IM, Subcutaneous 167
boceprevir 168
Category and Schedule 168
Drug Class: 168
Mechanism of Action 168
Uses 168
Pharmacokinetics 168
Indications and Dosages 169
► Treatment of Chronic Hepatitis C (CHC) 169
PO 169
Adults. 169
Side Effects/Adverse Reactions 169
Frequent 169
Occasional 169
Precautions and Contraindications 169
Drug Interactions of Concern to Dentistry 169
Serious Reactions 169
Dental Considerations 169
General: 169
Consultations: 169
Teach Patient/Family to: 169
bosentan 169
Category and Schedule 169
Drug Class: 169
Mechanism of Action 170
Uses 170
Pharmacokinetics 170
Indications and Dosages 170
► PAH in Those with WHO Class III or IV Symptoms 170
PO 170
Adults, Elderly. 170
Children weighing less than 40 kg. 170
Side Effects/Adverse Reactions 170
Occasional 170
Rare 170
Precautions and Contraindications 170
Caution: 170
Drug Interactions of Concern to Dentistry 170
Serious Reactions 170
Dental Considerations 170
General: 170
Teach Patient/Family to: 170
brexpiprazole 171
Category and Schedule 171
Drug Class: 171
Mechanism of Action 171
Uses 171
Pharmacokinetics 171
Indications and Dosages 171
► Major Depressive Disorder (Adjunct to Antidepressants) 171
brimonidine 172
Category and Schedule 172
Drug Class: 172
Mechanism of Action 172
Uses 172
Pharmacokinetics 172
Indications and Dosages 172
► Glaucoma, Ocular Hypertension 172
Ophthalmic 172
Adults, Elderly, Children 2 yr and older. 172
Side Effects/Adverse Reactions 173
Occasional 173
Precautions and Contraindications 173
Caution: 173
Drug Interactions of Concern to Dentistry 173
Serious Reactions 173
Dental Considerations 173
General: 173
Consultations: 173
Teach Patient/Family to: 173
brinzolamide 173
Category and Schedule 173
Drug Class: 173
bromocriptine mesylate 174
Category and Schedule 174
Drug Class: 174
Mechanism of Action 174
Uses 174
Pharmacokinetics 174
Indications and Dosages 174
► Glaucoma, Ocular Hypertension 174
Ophthalmic 174
Adults, Elderly. 174
Side Effects/Adverse Reactions 174
Occasional 174
Rare 174
Precautions and Contraindications 174
Caution: 174
Drug Interactions of Concern to Dentistry 174
Serious Reactions 174
Dental Considerations 174
General: 174
Consultations: 174
Uses 175
Pharmacokinetics 175
Indications and Dosages 175
► Hyperprolactinemia 175
brompheniramine 176
Category and Schedule 176
Drug Class: 176
Mechanism of Action 176
Uses 176
Pharmacokinetics 176
Indications and Dosages 176
► Allergic Rhinitis, Anaphylaxis, Urticarial Transfusion Reactions, Urticaria 176
PO 176
bucindolol 177
Drug Class: 177
Mechanism of Action 177
Uses 177
Pharmacokinetics 177
Indications and Dosages 177
► Hypertension 177
PO 177
Adults. 177
► Congestive Heart Failure 178
PO 178
Adults. 178
Side Effects/Adverse Reactions 178
Frequent 178
Occasional 178
Rare 178
Precautions and Contraindications 178
Caution: 178
Drug Interactions of Concern to Dentistry 178
Serious Reactions 178
Dental Considerations 178
General: 178
Consultations: 179
Teach Patient/Family to: 179
buclizine hydrochloride 179
Category and Schedule 179
Drug Class: 179
Mechanism of Action 179
Uses 179
Pharmacokinetics 179
Indications and Dosages 179
► Motion Sickness 179
PO 179
Adults, Elderly, Children 12 yr and older. 179
Side Effects/Adverse Reactions 179
Frequent 179
Occasional 179
Precautions and Contraindications 179
Drug Interactions of Concern to Dentistry 179
Serious Reactions 179
Dental Considerations 180
General: 180
Teach Patient/Family to: 180
budesonide 180
Category and Schedule 180
Drug Class: 180
Mechanism of Action 180
Uses 180
Pharmacokinetics 180
Indications and Dosages 180
► Rhinitis 180
Intranasal (Rhinocort Aqua) 180
bumetanide 181
Category and Schedule 181
Drug Class: 181
Mechanism of Action 181
Uses 181
Pharmacokinetics 182
Indications and Dosages 182
► Edema 182
bupivacaine 183
Category and Schedule 183
Drug Class: 183
Mechanism of Action 183
Uses 183
Pharmacokinetics 183
Indications and Dosages 183
► Analgesic, Epidural (partial to moderate motor blockade) 183
IV 183
Adults, Elderly. 183
Children weighing more than 10 kg. 183
Children weighing less than 10 kg. 183
► Analgesic, Epidural (moderate to complete motor blockade) 184
buprenorphine hydrochloride 186
Category and Schedule 186
Drug Class: 186
Mechanism of Action 186
Uses 186
Pharmacokinetics: 186
Indications and Dosages 187
► Analgesia 187
IV, IM 187
Adults, Children older than 12 yr. 187
Children 2–12 yr. 187
Elderly. 187
► Opioid Dependence 187
Sublingual 187
Adults, Elderly, Children older than 16 yr. 187
Side Effects/Adverse Reactions 187
Frequent 187
Occasional 187
Precautions and Contraindications 187
Caution: 187
Drug Interactions of Concern to Dentistry 187
Serious Reactions 187
Dental Considerations 187
General: 187
Consultations: 188
Teach Patient/Family to: 188
buprenorphine + naloxone 188
Category and Schedule 188
Drug Class: 188
Mechanism of Action 188
Uses 188
Pharmacokinetics 188
Indications and Dosages 188
► Opioid Dependence 188
Adults. 188
Side Effects/Adverse Reactions 188
Frequent 188
Occasional 188
Precautions and Contraindications 188
Drug Interactions of Concern to Dentistry 189
Serious Reactions 189
Dental Considerations 189
General: 189
Consultations: 189
Teach Patient/Family to: 189
bupropion 190
Category and Schedule 190
Drug Class: 190
Mechanism of Action 190
Uses 190
Pharmacokinetics 190
Indications and Dosages 190
► Depression 190
PO (Immediate-Release) 190
buspirone hydrochloride 191
Category and Schedule 191
Drug Class: 191
Mechanism of Action 191
Uses 191
Pharmacokinetics 191
Indications and Dosages 192
► Short-Term Management (up to 4 wk) of Anxiety Disorders 192
PO 192
Adults. 192
Elderly. 192
Children. 192
Side Effects/Adverse Reactions 192
Frequent 192
Occasional 192
Rare 192
Precautions and Contraindications 192
Caution: 192
Drug Interactions of Concern to Dentistry 192
Serious Reactions 192
Dental Considerations 192
General: 192
Consultations: 192
Teach Patient/Family: 192
busulfan 193
Category and Schedule 193
Drug Class: 193
Mechanism of Action 193
Uses 193
Pharmacokinetics 193
Indications and Dosages 193
► Remission Induction in Chronic Myelogenous Leukemia (CML) 193
butabarbital sodium 195
Category and Schedule 195
Drug Class: 195
Mechanism of Action 195
Uses 195
Pharmacokinetics 195
Indications and Dosages 195
► Insomnia, Short-Term 195
butenafine 196
Category and Schedule 196
Drug Class: 196
Mechanism of Action 196
Uses 196
Pharmacokinetics 196
Indications and Dosages 196
► Tinea Pedis, Tinea Corporis, Tinea Cruris, Tinea Versicolor 196
Topical 196
Adults, Elderly, Children 12 yr and older. 196
Side Effects/Adverse Reactions 196
Occasional 196
Rare 196
Precautions and Contraindications 196
Caution: 196
Drug Interactions of Concern to Dentistry 196
Serious Reactions 196
butoconazole 197
Category and Schedule 197
Drug Class: 197
Mechanism of Action 197
Uses 197
Pharmacokinetics 197
Indications and Dosages 197
► Treatment of Candidiasis 197
Topical 197
Adults, Elderly. 197
Side Effects/Adverse Reactions 197
Occasional 197
Precautions and Contraindications 197
Caution: 197
Serious Reactions 197
Dental Considerations 197
General: 197
Indications and Dosages 198
► Analgesia 198
IV 198
butorphanol tartrate 197
cabergoline 200
Category and Schedule 200
Drug Class: 200
Mechanism of Action 200
Uses 200
Pharmacokinetics 200
Indications and Dosages 200
► Hyperprolactinemia (Idiopathic or Primary Pituitary Adenomas) 200
calcifediol 201
Category and Schedule 201
Drug Class: 201
Mechanism of Action 201
Uses 201
Pharmacokinetics 201
Indications and Dosages 201
► Secondary Hyperparathyroidism 201
PO 201
Adults. 201
Side Effects/Adverse Reactions 202
Frequent 202
Occasional 202
Precautions and Contraindications 202
Drug Interactions of Concern to Dentistry 202
Serious Reactions 202
Dental Considerations 202
General: 202
Consultations: 202
Teach Patient/Family to: 202
calcitonin 202
Category and Schedule 202
Drug Class: 202
Mechanism of Action 202
Uses 202
Pharmacokinetics 202
Indications and Dosages 203
► Skin Testing Before Treatment in Patients with Suspected Sensitivity to Calcitonin-Salmon 203
Intracutaneous 203
canagliflozin 204
Category and Schedule 204
Drug Class: 204
Mechanism of Action 204
Uses 204
Pharmacokinetics 204
Indications and Dosages 204
► Type 2 Diabetes Mellitus 204
PO 204
Adults. 204
Side Effects/Adverse Reactions 204
Frequent 204
Occasional 204
Precautions and Contraindications 204
Drug Interactions of Concern to Dentistry 205
Serious Reactions 205
Dental Considerations 205
General: 205
Consultations: 205
Teach Patient/Family to: 205
canakinumab 205
Category and Schedule 205
Drug Class: 205
Mechanism of Action 205
Uses 205
Pharmacokinetics 205
Indications and Dosages 206
► Cryopyrin-Associated Periodic Syndrome (CAPS) 206
Children ≥4 yr and adolescents. 206
Children ≥4 yr and adolescents >40 kg. 206
► Systemic Juvenile Idiopathic Arthritis (SJIA) 206
Children ≥2 yr and ≥7.5 kg and adolescents. 206
Side Effects/Adverse Reactions 206
Frequent 206
Occasional 206
Precautions and Contraindications 206
Drug Interactions of Concern to Dentistry 206
Serious Reactions 206
Dental Considerations 206
General: 206
Teach Patient/Family to: 206
candesartan cilexetil 207
Category and Schedule 207
Drug Class: 207
Mechanism of Action 207
Uses 207
Pharmacokinetics 207
Indications and Dosages 207
► Hypertension Alone or in Combination with Other Antihypertensives 207
PO 207
Adults, Elderly, Patients with mildly impaired liver or renal function. 207
Side Effects/Adverse Reactions 207
Occasional 207
Rare 207
Precautions and Contraindications 207
Caution: 207
Drug Interactions of Concern to Dentistry 207
Serious Reactions 207
Dental Considerations 207
General: 207
Consultations: 208
Teach Patient/Family to: 208
capecitabine 208
Category and Schedule 208
Drug Class: 208
Mechanism of Action 208
Uses 208
Pharmacokinetics 208
Indications and Dosages 208
► Metastatic Breast Cancer, Colon Cancer 208
PO 208
Adults, Elderly. 208
Side Effects/Adverse Reactions 208
Frequent 208
Occasional 208
Precautions and Contraindications 208
Caution: 209
Drug Interactions of Concern to Dentistry 209
Serious Reactions 209
Dental Considerations 209
General: 209
Consultations: 209
Teach Patient/Family to: 209
caprylidene 210
Category and Schedule 210
Drug Class: 210
Mechanism of Action 210
Uses 210
Pharmacokinetics 210
Indications and Dosages 210
► Dietary Management of Metabolic Processes Associated with Mild-to-Moderate Alzheimer’s Disease 210
PO 210
Adults. 210
Side Effects/Adverse Reactions 210
Frequent 210
Occasional 210
Precautions and Contraindications 210
Drug Interactions of Concern to Dentistry 210
Serious Reactions 210
Dental Considerations 210
General: 210
Consultations: 211
capsaicin 211
Category and Schedule 211
Drug Class: 211
Mechanism of Action 211
Uses 211
Pharmacokinetics 211
Indications and Dosages 211
► Treatment of Neuralgia, Osteoarthritis, Rheumatoid Arthritis 211
Topical 211
Adults, Elderly, Children older than 2 yr. 211
Side Effects/Adverse Reactions 211
Frequent 211
Precautions and Contraindications 211
Caution: 211
Drug Interactions of Concern to Dentistry 211
Serious Reactions 211
Dental Considerations 211
General: 211
Teach Patient/Family to: 211
captopril 212
Category and Schedule 212
Drug Class: 212
Mechanism of Action 212
Uses 212
Pharmacokinetics 212
Indications and Dosages 212
► Hypertension 212
carbachol 214
Category and Schedule 214
Drug Class: 214
Mechanism of Action 214
Uses 214
Pharmacokinetics 214
Indications and Dosages 214
► Glaucoma 214
carbamazepine 215
Category and Schedule 215
Drug Class: 215
Mechanism of Action 215
Uses 215
Pharmacokinetics 215
Indications and Dosages 215
► Seizure Control 215
carbamide peroxide 217
Category and Schedule 217
Drug Class: 217
Mechanism of Action 217
Uses 217
Pharmacokinetics 217
Indications and Dosages 217
► Earwax Removal 217
carbidopa 218
Category and Schedule 218
Drug Class: 218
Mechanism of Action 218
Uses 218
Pharmacokinetics 218
Indications and Dosages 218
► Parkinson’s Disease 218
PO 218
Adults, Patients receiving carbidopa-levodopa 10/100. 218
Patients receiving carbidopa-levodopa 25/250 or carbidopa-levodopa 25/100. 218
Side Effects/Adverse Reactions 218
Frequent 218
Occasional 219
Precautions and Contraindications 219
Drug Interactions of Concern to Dentistry 219
Serious Reactions 219
Dental Considerations 219
General: 219
Teach Patient/Family to: 219
carbidopa + levodopa 219
Category and Schedule 219
Drug Class: 219
Mechanism of Action 219
Uses 219
Pharmacokinetics 220
Indications and Dosages 220
► Treatment of Motor Fluctuations in Patients With Advanced Parkinson’s Disease 220
Adults. 220
Side Effects/Adverse Reactions 220
Frequent 220
Occasional 220
Precautions and Contraindications 220
Drug Interactions of Concern to Dentistry 220
Serious Reactions 220
Dental Considerations 220
General: 220
Consultations: 221
Teach Patient/Family to: 221
carbinoxamine maleate 221
Category and Schedule 221
Drug Class: 221
Mechanism of Action 221
Uses 221
Pharmacokinetics 221
Indications and Dosages 221
► Allergic Rhinitis 221
PO 221
Adults, Children 6 yr and older. 221
Children 18 mo–6 yr. 221
Children 9–18 mo. 221
Side Effects/Adverse Reactions 221
Frequent 221
Occasional 222
Rare 222
Precautions and Contraindications 222
Drug Interactions of Concern to Dentistry 222
Serious Reactions 222
Dental Considerations 222
General: 222
Teach Patient/Family to: 222
carboplatin 222
Category and Schedule 222
Drug Class: 222
Mechanism of Action 222
Uses 222
Pharmacokinetics 222
Indications and Dosages 222
► Ovarian Carcinoma (Monotherapy) 222
IV 222
Adults. 222
► Ovarian Carcinoma (Combination Therapy) 223
Adults. 223
Children. 223
► Dosage in Renal Impairment 223
Side Effects/Adverse Reactions 223
Frequent 223
Occasional 223
Rare 223
Precautions and Contraindications 223
Drug Interactions of Concern to Dentistry 223
Serious Reactions 223
Dental Considerations 223
General: 223
Consultations: 223
Teach Patient/Family to: 224
carglumic acid 224
Category and Schedule 224
Drug Class: 224
Mechanism of Action 224
Uses 224
Pharmacokinetics 224
Indications and Dosages 224
► Acute Hyperammonemia 224
PO 224
Adults, Children. 224
► Chronic Hyperammonemia 225
PO 225
Adults, Children. 225
Side Effects/Adverse Reactions 225
Frequent 225
Occasional 225
Precautions and Contraindications 225
Drug Interactions of Concern to Dentistry 225
Serious Reactions 225
Dental Considerations 225
General: 225
Consultations: 225
Teach Patient/Family to: 225
carisoprodol 225
Category and Schedule 225
Drug Class: 225
Mechanism of Action 225
Uses 225
Pharmacokinetics 225
carmustine 226
Category and Schedule 226
Drug Class: 226
Mechanism of Action 226
Uses 226
Pharmacokinetics 226
Indications and Dosages 226
► Adjunct to Rest, Physical Therapy, Analgesics, and Other Measures for Relief of Discomfort from Acute, Painful Musculoskeletal Conditions 226
PO 226
► Disseminated Hodgkin’s Disease, Non-Hodgkin’s Lymphoma, Multiple Myeloma, and Primary and Metastatic Brain Tumors in Previously Untreated Patients (Monotherapy) 226
IV (BiCNu) 226
Adults, Elderly. 226
Side Effects/Adverse Reactions 226
Frequent 226
Occasional 226
Precautions and Contraindications 226
Caution: 226
Drug Interactions of Concern to Dentistry 226
Serious Reactions 226
Dental Considerations 226
General: 226
Teach Patient/Family to: 226
Children. 226
► Implantation (Gliadel) 226
Adults, Elderly, Children. 226
Side Effects/Adverse Reactions 227
Frequent 227
Occasional 227
Rare 227
Precautions and Contraindications 227
Drug Interactions of Concern to Dentistry 227
Serious Reactions 227
Dental Considerations 227
General: 227
Consultations: 227
Teach Patient/Family to: 227
carteolol 228
Category and Schedule 228
Drug Class: 228
Mechanism of Action 228
Uses 228
Pharmacokinetics 228
Indications and Dosages 228
► Ocular Hypertension 228
PO 228
carvedilol 230
Category and Schedule 230
Drug Class: 230
Mechanism of Action 230
Uses 230
Pharmacokinetics 230
Indications and Dosages 230
► Hypertension 230
cefaclor 232
Category and Schedule 232
Drug Class: 232
Mechanism of Action 232
Uses 232
Pharmacokinetics 232
Indications and Dosages 232
► Bronchitis 232
cefadroxil 233
Category and Schedule 233
Drug Class: 233
Mechanism of Action 233
Uses 234
Pharmacokinetics 234
Indications and Dosages 234
► UTIs 234
cefazolin sodium 235
Category and Schedule 235
Drug Class: 235
Mechanism of Action 235
Uses 235
Pharmacokinetics 235
Indications and Dosages 235
► Uncomplicated UTIs 235
cefdinir 237
Category and Schedule 237
Drug Class: 237
Mechanism of Action 237
Uses 237
Pharmacokinetics 237
Indications and Dosages 237
► Community-Acquired Pneumonia 237
cefditoren pivoxil 238
Category and Schedule 238
Drug Class: 238
Mechanism of Action 238
Uses 239
Pharmacokinetics 239
Indications and Dosages 239
► Pharyngitis, Tonsillitis, Skin Infections 239
cefepime 240
Category and Schedule 240
Drug Class: 240
Mechanism of Action 240
Uses 240
Pharmacokinetics 240
Indications and Dosages 240
► Pneumonia 240
IV 240
Adults, Elderly. 240
Children 2 mo and older. 240
► Intraabdominal Infections 241
cefixime 242
Category and Schedule 242
Drug Class: 242
Mechanism of Action 242
Uses 242
Pharmacokinetics 242
Indications and Dosages 242
► Otitis Media, Acute Bronchitis, Acute Exacerbations of Chronic Bronchitis, Pharyngitis, Tonsillitis, and Uncomplicated UTIs 242
cefonicid sodium 243
Category and Schedule 243
Drug Class: 243
Mechanism of Action 243
Uses 243
Pharmacokinetics 243
Indications and Dosages 243
► UTIs 243
cefoperazone 245
Category and Schedule 245
Drug Class: 245
Mechanism of Action 245
Uses 245
Pharmacokinetics 245
Indications and Dosages 245
► Mild to Moderate Infections 245
cefotaxime sodium 246
Category and Schedule 246
Drug Class: 246
Mechanism of Action 246
Uses 246
Pharmacokinetics 246
Indications and Dosages 246
► Uncomplicated Infections 246
cefotetan disodium 248
Category and Schedule 248
Drug Class: 248
Mechanism of Action 248
Uses 248
Pharmacokinetics 248
Indications and Dosages 248
► UTIs 248
cefoxitin sodium 249
Category and Schedule 249
Drug Class: 249
Mechanism of Action 249
Uses 249
Pharmacokinetics 249
Indications and Dosages 250
► Mild to Moderate Infections 250
cefpodoxime proxetil 251
Category and Schedule 251
Drug Class: 251
Mechanism of Action 251
Uses 251
Pharmacokinetics 251
Indications and Dosages 251
► Chronic Bronchitis, Pneumonia 251
cefprozil 253
Category and Schedule 253
Drug Class: 253
Mechanism of Action 253
Uses 253
Pharmacokinetics 253
Indications and Dosages 253
► Pharyngitis, Tonsillitis 253
ceftaroline fosamil 254
Category and Schedule 254
Drug Class: 254
Mechanism of Action 254
Uses 254
Pharmacokinetics 254
Indications and Dosages 254
► Pneumonia, Community-Acquired 254
ceftazidime 255
Category and Schedule 255
Drug Class: 255
Mechanism of Action 255
Uses 256
Pharmacokinetics 256
Indications and Dosages 256
► UTIs 256
ceftibuten 257
Category and Schedule 257
Drug Class: 257
Mechanism of Action 257
Uses 257
Pharmacokinetics 257
Indications and Dosages 257
► Chronic Bronchitis 257
ceftizoxime sodium 259
Category and Schedule 259
Drug Class: 259
Mechanism of Action 259
Uses 259
Pharmacokinetics 259
Indications and Dosages 259
► Uncomplicated UTIs 259
ceftriaxone sodium 260
Category and Schedule 260
Drug Class: 260
Mechanism of Action 260
Uses 260
Pharmacokinetics 260
Indications and Dosages 260
► Mild to Moderate Infections 260
IV, IM 260
Adults, Elderly. 260
► Serious Infections 261
cefuroxime axetil/cefuroxime sodium 262
Category and Schedule 262
Drug Class: 262
Mechanism of Action 262
Uses 262
Pharmacokinetics 262
Indications and Dosages 262
► Ampicillin-Resistant Influenza; Bacterial Meningitis; Early Lyme Disease; GU Tract, Gynecologic, Skin and Bone Infections; Septicemia; Gonorrhea and Other Gonococcal Infections 262
IV, IM 262
celecoxib 264
Category and Schedule 264
Drug Class: 264
Mechanism of Action 264
Uses 264
Pharmacokinetics 264
Indications and Dosages 264
► Osteoarthritis 264
cephalexin 265
Category and Schedule 265
Drug Class: 265
Mechanism of Action 265
Uses 266
Pharmacokinetics 266
Indications and Dosages 266
► Bone Infections, Prophylaxis of Rheumatic Fever, Follow-up to Parenteral Therapy 266
cephradine 267
Category and Schedule 267
Drug Class: 267
Mechanism of Action 267
Uses 267
Pharmacokinetics 267
Indications and Dosages 267
► Mild, Moderate or Severe Infections of the Respiratory and GU Tracts; Bone, Joint and Skin Infections; Prostatitis; Otitis Media 267
PO 267
Adults, Elderly. 267
Children older than 9 mo. 267
► Dosage in Renal Impairment 267
Side Effects/Adverse Reactions 268
Frequent 268
Occasional 268
Rare 268
Precautions and Contraindications 268
Caution: 268
Drug Interactions of Concern to Dentistry 268
Serious Reactions 268
Dental Considerations 268
General: 268
Consultations: 268
Teach Patient/Family to: 268
certolizumab 268
Category and Schedule 268
Drug Class: 268
Mechanism of Action 268
Uses 269
Pharmacokinetics 269
Indications and Dosages 269
Adult. 269
Pediatric. 269
Side Effects/Adverse Reactions 269
Frequent 269
Occasional 269
Rare 269
Precautions and Contraindications 269
Caution: 269
Drug Interactions of Concern to Dentistry 269
Serious Reactions 269
Dental Considerations 269
General: 269
Consultations: 269
Teach Patient/Family to: 270
cetirizine 270
Category and Schedule 270
Drug Class: 270
Mechanism of Action 270
Uses 270
Pharmacokinetics 270
Indications and Dosages 270
► Allergic Rhinitis, Urticaria 270
PO 270
Adults, Elderly, Children older than 5 yr. 270
Children 2–5 yr. 270
Children 12–23 mo. 270
Children 6–11 mo. 270
► Dosage in Renal or Hepatic Impairment 270
Side Effects/Adverse Reactions 270
Occasional 270
Precautions and Contraindications 270
Caution: 270
Drug Interactions of Concern to Dentistry 270
Serious Reactions 271
Dental Considerations 271
General: 271
Teach Patient/Family: 271
cetuximab 271
Category and Schedule 271
Drug Class: 271
Mechanism of Action 271
Uses 271
Pharmacokinetics 271
Indications and Dosages 271
► Metastatic Colorectal Carcinoma 271
IV 271
Adults, Elderly. 271
Side Effects/Adverse Reactions 271
Frequent 271
Occasional 271
Rare 271
Precautions and Contraindications 271
Drug Interactions of Concern to Dentistry 271
Serious Reactions 272
Dental Considerations 272
General: 272
Consultations: 272
Teach Patient/Family to: 272
cevimeline 272
Category and Schedule 272
Drug Class: 272
Mechanism of Action 272
Uses 273
Pharmacokinetics 273
Indications and Dosages 273
► Dry Mouth 273
PO 273
Adults. 273
Side Effects/Adverse Reactions 273
Frequent 273
Occasional 273
Rare 273
Precautions and Contraindications 273
Caution: 273
Drug Interactions of Concern to Dentistry 273
Serious Reactions 273
Dental Considerations 273
General: 273
Consultations: 273
Teach Patient/Family to: 273
chloral hydrate 274
Category and Schedule 274
Drug Class: 274
Mechanism of Action 274
Uses 274
Pharmacokinetics 274
Indications and Dosages 274
► Premedication for Dental or Medical Procedures 274
chlordiazepoxide 275
Category and Schedule 275
Drug Class: 275
Mechanism of Action 275
Uses 275
Pharmacokinetics 275
Indications and Dosages 275
► Alcohol Withdrawal Symptoms 275
chlorhexidine gluconate 276
Category and Schedule 276
Drug Class: 276
Mechanism of Action 276
Uses 277
Pharmacokinetics 277
Indications and Dosages 277
► Gingivitis 277
Oral Rinse 277
chloroquine/chloroquine phosphate 277
Category and Schedule 277
Drug Class: 277
Mechanism of Action 278
Uses 278
Pharmacokinetics 278
Indications and Dosages 278
Chloroquine Phosphate 278
► Treatment of Malaria (Acute Attack): Dose (mg Base) 278
► Suppression of Malaria 278
chlorothiazide 279
Category and Schedule 279
Drug Class: 279
Mechanism of Action 279
Uses 279
Pharmacokinetics 279
Indications and Dosages 279
► Edema, Hypertension 279
PO 279
Adults. 279
Children 12 yr and older. 279
Children 2–12 yr. 279
Children 6 mo–2 yr. 279
Children younger than 6 mo. 280
► Hypertension 280
IV 280
Side Effects/Adverse Reactions 280
Expected 280
Frequent 280
Occasional 280
Precautions and Contraindications 280
Caution: 280
Drug Interactions of Concern to Dentistry 280
Serious Reactions 280
Dental Considerations 280
General: 280
Consultations: 280
Teach Patient/Family to: 281
chlorpheniramine 281
Category and Schedule 281
Drug Class: 281
Mechanism of Action 281
Uses 281
Pharmacokinetics 281
Indications and Dosages 281
► Allergic Rhinitis, Common Cold 281
PO 281
chlorpromazine 282
Category and Schedule 282
Drug Class: 282
Mechanism of Action 282
Uses 283
Pharmacokinetics 283
Indications and Dosages 283
► Severe Nausea or Vomiting 283
chlorpropamide 285
Category and Schedule 285
Drug Class: 285
Mechanism of Action 285
Uses 285
Pharmacokinetics 285
Indications and Dosages 285
► Diabetes Mellitus, Combination Therapy 285
PO 285
Adults. 285
Elderly. 285
► Renal Function Impairment 285
Side Effects/Adverse Reactions 285
Frequent 285
Occasional 285
Precautions and Contraindications 285
Caution: 285
Drug Interactions of Concern to Dentistry 285
Serious Reactions 285
Dental Considerations 285
General: 285
Consultations: 286
Teach Patient/Family to: 286
chlorthalidone 286
Category and Schedule 286
Drug Class: 286
Mechanism of Action 286
Uses 286
Pharmacokinetics 286
Indications and Dosages 286
► Hypertension, Edema 286
PO 286
Adults. 286
Elderly. 286
Side Effects/Adverse Reactions 286
Expected 286
Frequent 286
Occasional 286
Rare 286
Precautions and Contraindications 286
Caution: 287
Drug Interactions of Concern to Dentistry 287
Serious Reactions 287
Dental Considerations 287
General: 287
Consultations: 287
Teach Patient/Family to: 287
chlorzoxazone 287
Category and Schedule 287
Drug Class: 287
cholestyramine resin 288
Category and Schedule 288
Drug Class: 288
Mechanism of Action 288
Uses 288
Pharmacokinetics 288
Indications and Dosages 288
► Musculoskeletal Pain 288
PO 288
Adults, Elderly. 288
Children. 288
Side Effects/Adverse Reactions 288
Frequent 288
Occasional 288
Precautions and Contraindications 288
Caution: 288
Drug Interactions of Concern to Dentistry 288
Serious Reactions 288
Dental Considerations 288
General: 288
Indications and Dosages 289
► Primary Hypercholesterolemia 289
cholic acid 289
Category and Schedule 289
Drug Class: 289
Mechanism of Action 289
Uses 289
Pharmacokinetics 289
Indications and Dosages 290
► Bile Acid Synthesis Disorders, Peroxisomal Disorders 290
PO 290
Adults. 290
Side Effects/Adverse Reactions 290
Frequent 290
Occasional 290
Precautions and Contraindications 290
Drug Interactions of Concern to Dentistry 290
Serious Reactions 290
Dental Considerations 290
General: 290
Consultations: 290
Teach Patient/Family to: 290
ciclesonide 290
Category and Schedule 290
Drug Class: 290
Mechanism of Action 290
Pharmacokinetics 291
Indications and Dosages 291
► Asthma 291
Oral Inhalation (Alvesco) 291
Adults, Children 12 yr and older. 291
► Allergic Rhinitis 291
Nasal (Omnaris) 291
Adults, Children 6 yr and older. 291
Side Effects/Adverse Reactions 291
Frequent 291
Occasional 291
Rare 291
Precautions and Contraindications 291
Drug Interactions of Concern to Dentistry 291
Serious Reactions 291
Dental Considerations 291
General: 291
Consultations: 292
Teach Patient/Family to: 292
ciclopirox 292
Category and Schedule 292
Drug Class: 292
Mechanism of Action 292
Uses 292
Pharmacokinetics 292
Indications and Dosages 292
► Tinea Pedis 292
cimetidine 293
Category and Schedule 293
Drug Class: 293
Mechanism of Action 293
Uses 293
Pharmacokinetics 293
Indications and Dosages 293
► Active Ulcer 293
ciprofloxacin hydrochloride 295
Category and Schedule 295
Drug Class: 295
Mechanism of Action 295
Uses 295
Pharmacokinetics 295
Indications and Dosages 295
► Mild to Moderate UTIs 295
cisplatin 297
Category and Schedule 297
Drug Class: 297
Mechanism of Action 297
Uses 297
Pharmacokinetics 297
Indications and Dosages 297
► Advanced Bladder Carcinoma, Metastatic Ovarian Tumors, Metastatic Testicular Tumors 297
IV 297
Adults, Elderly, Children. 297
► Dosage in Renal Impairment 297
Side Effects/Adverse Reactions 298
Frequent 298
Occasional 298
Rare 298
Precautions and Contraindications 298
Drug Interactions of Concern to Dentistry 298
Serious Reactions 298
Dental Considerations 298
General: 298
Consultations: 298
Teach Patient/Family to: 299
clarithromycin 299
Category and Schedule 299
Drug Class: 299
Mechanism of Action 299
Uses 299
Pharmacokinetics 299
Indications and Dosages 299
► Bronchitis 299
clemastine fumarate 301
Category and Schedule 301
Drug Class: 301
Mechanism of Action 301
Uses 301
Pharmacokinetics 301
Indications and Dosages 301
► Allergic Rhinitis, Urticaria 301
PO 301
Adults, Children older than 11 yr. 301
Children 6–11 yr. 301
Children younger than 6 yr. 301
Elderly. 301
Side Effects/Adverse Reactions 301
Frequent 301
Occasional 301
Precautions and Contraindications 301
Caution: 301
Drug Interactions of Concern to Dentistry 301
Serious Reactions 302
Dental Considerations 302
General: 302
Teach Patient/Family to: 302
clevidipine 302
Category and Schedule 302
Drug Class: 302
Mechanism of Action 302
Uses 302
Pharmacokinetics 302
Indications and Dosages 303
► Hypertension when Oral Therapy Is Not Feasible or Desired, Perioperative Hypertension, Hypertensive Urgency, and Hypertensive Emergency 303
IV 303
Adults. 303
Side Effects/Adverse Reactions 303
Frequent 303
Occasional 303
Precautions and Contraindications 303
Caution: 303
Drug Interactions of Concern to Dentistry 303
Serious Reactions 303
Dental Considerations 303
General: 303
Consultations: 303
Teach Patient/Family to: 303
clindamycin 304
Category and Schedule 304
Drug Class: 304
Mechanism of Action 304
Uses 304
Pharmacokinetics 304
Indications and Dosages 304
► Chronic Bone and Joint, Respiratory Tract, Skin and Soft Tissue, Intraabdominal, and Female GU Infections; Endocarditis; Septicemia 304
clindamycin + tretinoin 305
Category and Schedule 305
Drug Class: 305
Mechanism of Action 305
Uses 305
clobazam 306
Category and Schedule 306
Drug Class: 306
Mechanism of Action 306
Uses 306
Pharmacokinetics 306
Indications and Dosages 306
► Acne Vulgaris 306
Topical 306
Adults, Children 12 yr and older. 306
Side Effects/Adverse Reactions 306
Frequent 306
Occasional 306
Precautions and Contraindications 306
Drug Interactions of Concern to Dentistry 306
Serious Reactions 306
Dental Considerations 306
General: 306
Teach Patient/Family to: 306
Indications and Dosages 307
► Lennox-Gastaut (adjunctive) 307
PO 307
Adults, Children 2 yr or older weighing less than 30 kg. 307
Children weighing more than 30 kg. 307
Elderly weighing less than 30 kg. 307
Elderly weighing more than 30 kg. 307
Side Effects/Adverse Reactions 307
Frequent 307
Occasional 307
Precautions and Contraindications 307
Drug Interactions of Concern to Dentistry 307
Serious Reactions 307
Dental Considerations 307
General: 307
Consultations: 307
Teach Patient/Family to: 308
clobetasol 308
Category and Schedule 308
Drug Class: 308
Mechanism of Action 308
Uses 308
Pharmacokinetics 308
Indications and Dosages 308
► Antiinflammatory, Corticosteroid Replacement Therapy 308
Topical 308
clocortolone 309
Category and Schedule 309
Drug Class: 309
Mechanism of Action 309
Uses 309
Pharmacokinetics 309
Indications and Dosages 309
► Dermatoses 309
Topical 309
Adults, Elderly, Children 12 yr and older. 309
Side Effects/Adverse Reactions 309
Occasional 309
Rare 309
Precautions and Contraindications 309
Caution: 309
Drug Interactions of Concern to Dentistry 309
Serious Reactions 309
Dental Considerations 310
General: 310
clofarabine 310
Category and Schedule 310
Drug Class: 310
Mechanism of Action 310
Uses 310
Pharmacokenetics 310
Indications and Dosages 310
► ALL 310
IV 310
Adults. 310
Children. 310
Side Effects/Adverse Reactions: 310
Frequent 310
Occasional 310
Precautions and Contraindications 311
Caution: 311
Drug Interactions of Concern to Dentistry 311
Serious Reactions 311
Dental Considerations 311
General: 311
Consultations: 311
Teach Family/Patient to: 311
clofazimine 311
Category and Schedule 311
Drug Class: 311
Mechanism of Action 311
clofibrate 312
Category and Schedule 312
Drug Class: 312
Mechanism of Action 312
Uses 312
Pharmacokinetics 312
Indications and Dosages 312
► Leprosy 312
Indications and Dosages 313
► Hypercholesterolemia 313
PO 313
Adults, Elderly. 313
Side Effects/Adverse Reactions 313
Frequent 313
Occasional 313
Rare 313
Precautions and Contraindications 313
Caution: 313
Drug Interactions of Concern to Dentistry 313
Serious Reactions 313
Dental Considerations 313
General: 313
Consultations: 313
Teach Patient/Family to: 313
clomiphene 313
Category and Schedule 313
Drug Class: 313
Mechanism of Action 313
Uses 313
Pharmacokinetics 313
Indications and Dosages 314
► Ovulatory Failure, Females 314
PO 314
Adults. 314
Side Effects/Adverse Reactions 314
Frequent 314
Occasional 314
Rare 314
Precautions and Contraindications 314
Caution: 314
Drug Interactions of Concern to Dentistry 314
Serious Reactions 314
Dental Considerations 314
General: 314
clomipramine hydrochloride 314
Category and Schedule 314
Drug Class: 314
Mechanism of Action 314
Uses 314
Pharmacokinetics 315
Indications and Dosages 315
► Obsessive-Compulsive Disorder 315
PO 315
Adults, Elderly. 315
Children 10 yr and older. 315
Side Effects/Adverse Reactions 315
Frequent 315
Occasional 315
Rare 315
Precautions and Contraindications 315
Caution: 315
Drug Interactions of Concern to Dentistry 315
Serious Reactions 315
Dental Considerations 315
General: 315
Consultations: 316
Teach Patient/Family to: 316
clonazepam 316
Category and Schedule 316
Drug Class: 316
Mechanism of Action 316
Uses 316
Pharmacokinetics 316
Indications and Dosages 316
► Adjunctive Treatment of Lennox-Gastaut Syndrome (Petit Mal Variant) and Akinetic, Myoclonic, and Absence (Petit Mal) Seizures 316
PO 316
Adults, Elderly, Children 10 yr and older. 316
Infants, Children younger than 10 yr or weighing less than 30 kg. 317
► Panic Disorder 317
PO 317
Adults, Elderly. 317
Side Effects/Adverse Reactions 317
Frequent 317
Occasional 317
Rare 317
Precautions and Contraindications 317
Caution: 317
Drug Interactions of Concern to Dentistry 317
Serious Reactions 317
Dental Considerations 317
General: 317
Consultations: 317
Teach Patient/Family to: 318
clonidine 318
Category and Schedule 318
Drug Class: 318
Mechanism of Action 318
Uses 318
Pharmacokinetics 318
Indications and Dosages 318
► Hypertension 318
clopidogrel 320
Category and Schedule 320
Drug Class: 320
Mechanism of Action 320
Uses 320
Pharmacokinetics 320
Indications and Dosages 320
► MI, Stroke Reduction 320
clorazepate dipotassium 321
Category and Schedule 321
Drug Class: 321
Mechanism of Action 321
Uses 321
Pharmacokinetics 321
Indications and Dosages 321
► Anxiety 321
PO (Regular-Release) 321
clotrimazole 323
Category and Schedule 323
Drug Class: 323
Mechanism of Action 323
Uses 323
Pharmacokinetics 323
Indications and Dosages 323
► Oropharyngeal Candidiasis Treatment 323
clozapine 324
Category and Schedule 324
Drug Class: 324
Mechanism of Action 324
Uses 324
Pharmacokinetics 324
Indications and Dosages 324
► Schizophrenic Disorders, Reduce Suicidal Behavior 324
PO 324
Adults. 324
Elderly. 324
Side Effects/Adverse Reactions 324
Frequent 324
Occasional 324
Rare 324
Precautions and Contraindications 324
Caution: 325
Drug Interactions of Concern to Dentistry 325
Serious Reactions 325
Dental Considerations 325
General: 325
Consultations: 325
Teach Patient/Family to: 325
cocaine hydrochloride 326
Category and Schedule 326
Drug Class: 326
Mechanism of Action 326
Uses 326
Pharmacokinetics 326
Indications and Dosages 326
► Anesthesia 326
Topical 326
Adults, Elderly, Children. 326
Side Effects/Adverse Reactions 326
Frequent 326
Occasional 326
Precautions and Contraindications 326
Drug Interactions of Concern to Dentistry 326
Serious Reactions 326
Dental Considerations 326
General: 326
Consultations: 327
Teach Patient/Family: 327
codeine phosphate/codeine sulfate 327
Category and Schedule 327
Drug Class: 327
Mechanism of Action 327
Uses 327
Pharmacokinetics 327
Indications and Dosages 328
► Analgesia 328
PO, IM, subcutaneous 328
Adults, Elderly. 328
Children. 328
► Cough 328
PO 328
Adults, Elderly, Children 12 yr and older. 328
Children 6–11 yr. 328
Children 2–5 yr. 328
► Dosage in Renal Impairment 328
Side Effects/Adverse Reactions 328
Frequent 328
Occasional 328
Rare 328
Precautions and Contraindications 328
Caution: 328
Drug Interactions of Concern to Dentistry 328
Serious Reactions 328
Dental Considerations 328
General: 328
Teach Patient/Family: 328
colchicine 329
Category and Schedule 329
Drug Class: 329
Mechanism of Action 329
Uses 329
Pharmacokinetics 329
Indications and Dosages 329
► Acute Gouty Arthritis 329
colesevelam 330
Category and Schedule 330
Drug Class: 330
Mechanism of Action 330
Uses 330
Pharmacokinetics 330
Indications and Dosages 330
► Primary Hyperlipidemia (Used as Monotherapy or in Combinations with an HMG COA Reductase Inhibitor, or “Statin”) 330
colestipol 331
Category and Schedule 331
Drug Class: 331
Mechanism of Action 331
Uses 331
Pharmacokinetics 331
Indications and Dosages 331
► Primary Hypercholesterolemia 331
PO, Granules 331
conivaptan 332
Category and Schedule 332
Drug Class: 332
Mechanism of Action 332
Uses 332
Pharmacokinetics 332
Indications and Dosages 332
► Hyponatremia 332
IV 332
Adults. 332
Side Effects/Adverse Reactions 333
Frequent 333
Occasional 333
Precautions and Contraindications 333
Caution: 333
Drug Interactions of Concern to Dentistry 333
Serious Reactions 333
Dental Considerations 333
Consultations: 333
Teach Patient/Family to: 333
cortisone acetate 333
Category and Schedule 333
Drug Class: 333
Mechanism of Action 333
Uses 333
Pharmacokinetics 334
Indications and Dosages 334
► Antiinflammation, Immunosuppression 334
cromolyn sodium 335
Category and Schedule 335
Drug Class: 335
Mechanism of Action 335
Uses 335
Pharmacokinetics 335
Indications and Dosages 335
► Asthma 335
Inhalation (Nebulization) 335
Adults, Elderly, Children older than 2 yr. 335
Aerosol spray 335
Adults, Elderly, Children 12 yr and older. 336
Children 5–11 yr. 336
► Prevention of Bronchospasm 336
Inhalation (Nebulization) 336
Adults, Elderly, Children older than 2 yr. 336
Aerosol spray 336
Adults, Elderly, Children older than 5 yr. 336
► Food Allergy, Inflammatory Bowel Disease 336
cyclobenzaprine hydrochloride 337
Category and Schedule 337
Drug Class: 337
Mechanism of Action 337
Uses 337
Pharmacokinetics 337
Indications and Dosages 337
► Acute, Painful Musculoskeletal Conditions 337
PO 337
Adults. 337
Elderly. 337
► Dosage in Hepatic Impairment 338
Mild. 338
Moderate and severe. 338
cyclopentolate hydrochloride 339
Category and Schedule 339
Drug Class: 339
Mechanism of Action 339
Uses 339
Pharmacokinetics 339
Indications and Dosages 339
► Cycloplegia Induction, Mydriasis Induction 339
Ophthalmic 339
Adults, Elderly, Children. 339
Neonates, infants. 339
Side Effects/Adverse Reactions 339
Occasional 339
Rare 339
Precautions and Contraindications 339
Drug Interactions of Concern to Dentistry 339
Serious Reactions 339
Dental Considerations 339
General: 339
cyclophosphamide 340
Category and Schedule 340
Drug Class: 340
Mechanism of Action 340
Uses 340
Pharmacokinetics 340
Indications and Dosages 340
► Ovarian Adenocarcinoma, Breast Carcinoma, Hodgkin’s Disease, Non-Hodgkin’s Lymphoma, Multiple Myeloma, Leukemia (Acute Lymphoblastic, Acute Myelogenous, Acute Monocytic, Chronic Granulocytic, Chronic Lymphocytic), Mycosis Fungoides, Disseminated Neuroblastoma, Retinoblastoma 340
cycloserine 341
Category and Schedule 341
Drug Class: 341
Mechanism of Action 341
Uses 341
Pharmacokinetics 341
Indications and Dosages 342
► TB 342
Adults, Elderly. 342
Children. 342
► Dosage in Renal Impairment 342
Side Effects/Adverse Reactions 342
Occasional 342
Precautions and Contraindications 342
Drug Interactions of Concern to Dentistry 342
Serious Reactions/Adverse Reactions 342
Dental Considerations 342
General: 342
Consultation: 342
Teach Patient/Family to: 342
cyclosporine 343
Category and Schedule 343
Drug Class: 343
Mechanism of Action 343
Uses 343
Pharmacokinetics 343
Indications and Dosages 343
► Transplantation, Prevention of Organ Rejection 343
cyproheptadine 345
Category and Schedule 345
Drug Class: 345
Mechanism of Action 345
Uses 345
Pharmacokinetics 345
Indications and Dosages 345
► Allergic Condition 345
cysteamine bitartrate 346
Category and Schedule 346
Drug Class: 346
Mechanism of Action 346
Uses 346
Pharmacokinetics 346
Indications and Dosages 346
► Cystinosis 346
PO 346
Adults. 346
Children older than 12 yr and weighing more than 110 lb. 346
Children 6–12 yr. 346
Side Effects/Adverse Reactions 346
Frequent 346
Occasional 346
Precautions and Contraindications 346
Drug Interactions of Concern to Dentistry 346
Serious Reactions 347
Dental Considerations 347
General: 347
Consultations: 347
Teach Patient/Family to: 347
cytarabine 347
Category and Schedule 347
Drug Class: 347
Mechanism of Action 347
Uses 347
Pharmacokinetics 347
Indications and Dosages 347
► To Induce Remission in Acute Lymphocytic Leukemia, Acute and Chronic Myelocytic Leukemia, Meningeal Leukemia, or Non-Hodgkin’s Lymphoma in Children 347
dabigatran 350
Category and Schedule 350
Drug Class: 350
Mechanism of Action 350
Uses 350
Pharmacokinetics 350
Indications and Dosages 350
► Nonvalvular Atrial Fibrillation 350
daclizumab 351
Category and Schedule 351
Drug Class: 351
Mechanism of Action 351
Uses 351
Pharmacokinetics 351
Indications and Dosages 351
► Prevention of Acute Renal Transplant Rejection (in combination with an immunosuppressive) 351
IV 351
Adults, Children. 351
Side Effects/Adverse Reactions 351
Occasional 351
Precautions and Contraindications 352
Caution: 352
Drug Interactions of Concern to Dentistry 352
Serious Reactions 352
Dental Considerations 352
General: 352
Consultations: 352
Teach Patient/Family to: 352
dalfampridine 352
Category and Schedule 352
Drug Class: 352
Mechanism of Action 352
Uses 352
Pharmacokinetics 352
Indications and Dosages 352
► Multiple Sclerosis 352
PO 352
Adults. 352
Side Effects/Adverse Reactions 352
Frequent 352
Occasional 352
Rare 353
Precautions and Contraindications 353
Caution: 353
Drug Interactions of Concern to Dentistry 353
Serious Reactions 353
Dental Considerations 353
General: 353
Consultations: 353
Teach Patient/Family to: 353
dalteparin sodium 353
Category and Schedule 353
Drug Class: 353
Mechanism of Action 353
Uses 353
Pharmacokinetics 353
Indications and Dosages 353
► Low- to Moderate-Risk Abdominal Surgery 353
Subcutaneous 353
Adults, Elderly. 353
► High-Risk Abdominal Surgery 354
danaparoid 354
Category and Schedule 354
Drug Class: 354
Mechanism of Action 355
Uses 355
Pharmacokinetics 355
Indications and Dosages 355
► Prevention of DVT 355
Subcutaneous 355
Adults, Elderly. 355
Side Effects/Adverse Reactions 355
Frequent 355
Occasional 355
Rare 355
Precautions and Contraindications 355
Caution: 355
Drug Interactions of Concern to Dentistry 355
Serious Reactions 355
Dental Considerations 355
General: 355
Consultations: 356
Teach Patient/Family to: 356
danazol 356
Category and Schedule 356
Drug Class: 356
Mechanism of Action 356
Uses 356
Pharmacokinetics 356
Indications and Dosages 356
► Endometriosis 356
dantrolene sodium 357
Category and Schedule 357
Drug Class: 357
Mechanism of Action 357
Uses 357
Pharmacokinetics 357
Indications and Dosages 357
► Spasticity 357
PO 357
Adults, Elderly. 357
Children. 358
► Prevention of Malignant Hyperthermic Crisis 358
PO 358
dapagliflozin + metformin 359
Category and Schedule 359
Drug Class: 359
Mechanism of Action 359
Uses 359
Pharmacokinetics 359
Indications and Dosages 359
► Type 2 Diabetes Mellitus 359
PO 359
Adults. 359
Side Effects/Adverse Reactions 359
Frequent 359
Occasional 359
Precautions and Contraindications 359
Drug Interactions of Concern to Dentistry 360
Serious Reactions 360
Dental Considerations 360
General: 360
Consultations: 360
Teach Patient/Family to: 360
dapiprazole hydrochloride 360
Category and Schedule 360
Drug Class: 360
Mechanism of Action 360
Uses 360
Pharmacokinetics 360
Indications and Dosages 360
► Drug-Induced Mydriasis 360
Ophthalmic 360
Adults, Elderly, Children. 360
dapsone 361
Category and Schedule 361
Drug Class: 361
Mechanism of Action 361
Uses 361
Pharmacokinetics 361
Indications and Dosages 361
► Leprosy 361
daptomycin 362
Category and Schedule 362
Drug Class: 362
Mechanism of Action 362
Uses 362
Pharmacokinetics 362
Indications and Dosages 362
► Complicated Skin and Skin-Structure Infections 362
IV 362
Adults, Elderly. 362
► Dosage in Renal Impairment 362
Side Effects/Adverse Reactions 362
Frequent 362
Occasional 362
Rare 362
Precautions and Contraindications 363
Caution: 363
Drug Interactions of Concern to Dentistry 363
Serious Reactions 363
Dental Considerations 363
General: 363
Consultations: 363
darbepoetin alfa 363
Category and Schedule 363
Drug Class: 363
Mechanism of Action 363
Uses 363
Pharmacokinetics 363
Indications and Dosages 363
► Anemia in Chronic Renal Failure 363
IV Bolus, Subcutaneous 363
darifenacin 364
Category and Schedule 364
Drug Class: 364
Mechanism of Action 364
Uses 364
Pharmacokinetics 364
Indications and Dosages 365
► Symptoms of Bladder Overactivity 365
PO 365
Adults. 365
Side Effects/Adverse Reactions 365
Frequent 365
Occasional 365
Precautions and Contraindications 365
Drug Interactions of Concern to Dentistry 365
Serious Reactions 365
Dental Considerations 365
General: 365
Teach Patient/Family: 365
darunavir 365
Category and Schedule 365
Drug Class: 365
Mechanism of Action 365
Uses 366
Pharmacokenetics 366
Indications and Dosages 366
► HIV Infection (in combination with ritonavir) 366
PO 366
Adults. 366
Side Effects/Adverse Reactions 366
Frequent 366
Occasional 366
Rare 366
Precautions and Contraindications 366
Drug Interactions of Concern to Dentistry 366
Serious Reactions 366
Dental Considerations 367
General: 367
Consultations: 367
Teach Patient/Family to: 367
darunavir + cobicistat 367
Category and Schedule 367
Drug Class: 367
Mechanism of Action 367
Uses 367
Pharmacokinetics 367
Indications and Dosages 367
► HIV-1 Infection (treatment-naive or treatment-experienced patients without darunavir resistance–associated substitutions) 367
PO 367
Adults. 367
Side Effects/Adverse Reactions 368
Frequent 368
Occasional 368
Precautions and Contraindications 368
Drug Interactions of Concern to Dentistry 368
Serious Reactions 368
Dental Considerations 368
General: 368
Consultations: 369
Teach Patient/Family to: 369
dasatinib 369
Category and Schedule 369
Drug Class: 369
Mechanism of Action 369
Uses 369
Pharmacokenetics 369
Indications and Dosages 369
► ALL, Philadelphia Chromosome-Positive, Resistant or Intolerant to Prior Therapy 369
PO 369
daunorubicin citrate liposome 371
Category and Schedule 371
Drug Class: 371
Mechanism of Action 371
Uses 371
Pharmacokinetics 371
Indications and Dosages 371
► KS 371
IV 371
Adults. 371
Side Effects/Adverse Reactions 371
Frequent 371
Occasional 371
Rare 371
Precautions and Contraindications 371
Drug Interactions of Concern to Dentistry 371
Serious Reactions 371
Dental Considerations 371
General: 371
Consultations: 372
Teach Patient/Family to: 372
decitabine 372
Category and Schedule 372
Drug Class: 372
Mechanism of Action 372
Uses 372
Pharmacokinetics 372
Indications and Dosages 372
► MDS 372
IV 372
Adults. 372
Side Effects/Adverse Reactions 372
Frequent 372
Occasional 373
Rare 373
Precautions and Contraindications 373
Drug Interactions of Concern to Dentistry 373
Serious Reactions 373
Dental Considerations 373
General: 373
Consultations: 373
Teach Patient/Family to: 373
deferiprone 374
Category and Schedule 374
Drug Class: 374
Mechanism of Action 374
Uses 374
Pharmacokinetics 374
Indications and Dosages 374
► Transfusional Iron Overload 374
PO 374
Adults. 374
Side Effects/Adverse Reactions 374
Frequent 374
Occasional 374
Precautions and Contraindications 374
delavirdine mesylate 375
Category and Schedule 375
Drug Class: 375
Mechanism of Action 375
Uses 375
Pharmacokinetics 375
Indications and Dosages 375
► HIV Infection (in combination with other antiretrovirals) 375
PO 375
Adults. 375
Side Effects/Adverse Reactions 375
Frequent 375
Occasional 375
Precautions and Contraindications 375
Caution: 375
Drug Interactions of Concern to Dentistry 375
Serious Reactions 375
Dental Considerations 375
General: 375
Dental Considerations 376
General: 376
Consultations: 376
Teach Patient/Family to: 376
demecarium bromide 376
Category and Schedule 376
Drug Class: 376
Mechanism of Action 376
Uses 376
Pharmacokinetics 376
Indications and Dosages 376
► Glaucoma 376
demeclocycline hydrochloride 377
Category and Schedule 377
Drug Class: 377
Mechanism of Action 377
Uses 378
Pharmacokinetics 378
Indications and Dosages 378
► Mild-to-Moderate Infections, Including Acne, Pertussis, Chronic Bronchitis, and UTIs 378
deoxycholic acid 379
Category and Schedule 379
Drug Class: 379
Mechanism of Action 379
Uses 379
Pharmacokinetics 379
Indications and Dosages 379
► Submental Convexity/Fullness 379
Adults. 379
Side Effects/Adverse Reactions 379
Frequent 379
Occasional 379
Precautions and Contraindications 379
Drug Interactions of Concern to Dentistry 379
Serious Reactions 380
Dental Considerations 380
General: 380
Consultations: 380
Teach Patient/Family to: 380
desipramine hydrochloride 380
Category and Schedule 380
Drug Class: 380
Mechanism of Action 380
Uses 380
Pharmacokinetics 380
Indications and Dosages 380
► Depression 380
PO 380
Adults. 380
Elderly. 380
Children older than 12 yr. 380
Children 6–12 yr. 380
Side Effects/Adverse Reactions 380
Frequent 380
Occasional 381
Rare 381
Precautions and Contraindications 381
Caution: 381
Drug Interactions of Concern to Dentistry 381
Serious Reactions 381
Dental Considerations 381
General: 381
Consultations: 381
Teach Patient/Family to: 381
desirudin 382
Category and Schedule 382
Drug Class: 382
Mechanism of Action 382
Uses 382
Pharmacokinetics 382
Indications and Dosages 382
► Prevention of DVT in Patients Undergoing Hip Replacement Surgery 382
desloratadine 383
Category and Schedule 383
Drug Class: 383
Mechanism of Action 383
Uses 383
Pharmacokinetics 383
Indications and Dosages 383
► Allergic Rhinitis, Urticaria 383
PO 383
Adults, Elderly, Children older than 12 yr. 383
► Dosage in Hepatic or Renal Impairment 383
Side Effects/Adverse Reactions 383
Frequent 383
Occasional 383
Rare 383
Precautions and Contraindications 383
Caution: 383
Drug Interactions of Concern to Dentistry 384
Serious Reactions 384
Dental Considerations 384
General: 384
Teach Patient/Family to: 384
desmopressin 384
Category and Schedule 384
Drug Class: 384
Mechanism of Action 384
Uses 384
Pharmacokinetics 384
Indications and Dosages 384
► Primary Nocturnal Enuresis 384
desonide 386
Category and Schedule 386
Drug Class: 386
Mechanism of Action 386
Uses 386
Pharmacokinetics 386
Indications and Dosages 386
► Dermatoses 386
Topical 386
Adults, Elderly. 386
► Otitis Externa 386
Aural 386
Adults, Elderly, Children. 386
Side Effects/Adverse Reactions 386
Occasional 386
Precautions and Contraindications 386
Caution: 386
Drug Interactions of Concern to Dentistry 386
Serious Reactions 386
Dental Considerations 386
General: 386
desoximetasone 387
Category and Schedule 387
Drug Class: 387
Mechanism of Action 387
Uses 387
Pharmacokinetics 387
Indications and Dosages 387
► Dermatoses 387
Topical 387
Adults, Elderly. 387
Children. 387
Side Effects/Adverse Reactions 387
Frequent 387
Occasional 387
Rare 387
Precautions and Contraindications 387
Caution: 387
Serious Reactions 387
Dental Considerations 387
General: 387
Teach Patient/Family to: 387
desvenlafaxine 388
Category and Schedule 388
Drug Class: 388
Mechanism of Action 388
Uses 388
Pharmacokinetics 388
Indications and Dosages 388
► Major Depressive Disorder 388
PO 388
dexamethasone 389
Category and Schedule 389
Drug Class: 389
Mechanism of Action 389
Uses 390
Pharmacokinetics 390
Indications and Dosages 390
► Antiinflammatory 390
dexamethasone sodium phosphate 391
Category and Schedule 391
Drug Class: 391
Mechanism of Action 392
Uses 392
Pharmacokinetics 392
Indications and Dosages 392
► Ocular Inflammatory Conditions 392
Ophthalmic, Ointment 392
dexchlorpheniramine 393
Category and Schedule 393
Drug Class: 393
Mechanism of Action 393
Uses 393
Pharmacokinetics 393
Indications and Dosages 393
► Allergic Rhinitis, Common Cold 393
PO 393
Adults, Elderly, Children 12 yr or older. 393
Children 6–11 yr. 393
Children 2–5 yr. 393
Side Effects/Adverse Reactions 393
Frequent 393
Occasional 393
Precautions and Contraindications 393
Caution: 393
Drug Interactions of Concern to Dentistry 393
Serious Reactions 394
Dental Considerations 394
General: 394
Teach Patient/Family: 394
dexlansoprazole 394
Category and Schedule 394
Drug Class: 394
Mechanisn of Action 394
Uses 394
Pharmacokinetics 394
Indications and Dosages 394
► Erosive Esophagitis 394
dexmethylphenidate hydrochloride 395
Category and Schedule 395
Drug Class: 395
Mechanism of Action 395
Uses 395
Pharmacokinetics 395
Indications and Dosages 395
► ADHD 395
PO 395
Patients new to dexmethylphenidate or methylphenidate. 395
Patients currently taking methylphenidate. 396
Side Effects/Adverse Reactions 396
Frequent 396
Occasional 396
Rare 396
Precautions and Contraindications 396
Caution: 396
Drug Interactions of Concern to Dentistry 396
Serious Reactions 396
Dental Considerations 396
General: 396
Consultations: 396
Teach Patient/Family to: 396
dextroamphetamine sulfate 397
Category and Schedule 397
Drug Class: 397
Mechanism of Action 397
Uses 397
Pharmacokinetics 397
Indications and Dosages 397
► Narcolepsy 397
dextromethorphan 398
Category and Schedule 398
Drug Class: 398
Mechanism of Action 398
dextromethorphan + quinidine 399
Category and Schedule 399
Drug Class: 399
Mechanism of Action 399
Uses 399
Pharmacokinetics 399
Indications and Dosages 399
► Cough 399
PO 399
Adults, Elderly, Children 12 yr and older. 399
Children 6–12 yr. 399
Children 2–5 yr. 399
Side Effects/Adverse Reactions 399
Rare 399
Precautions and Contraindications 399
Caution: 399
Drug Interactions of Concern to Dentistry 399
Serious Reactions 399
Dental Considerations 399
General: 399
Indications and Dosages 400
► Pseudobulbar Affect (PBA) 400
PO 400
Adults. 400
Side Effects/Adverse Reactions 400
Frequent 400
Occasional 400
Precautions and Contraindications 400
Drug Interactions of Concern to Dentistry 400
Serious Reactions 400
Dental Considerations 400
General: 400
Teach Patient/Family to: 400
diazepam 401
Category and Schedule 401
Drug Class: 401
Mechanism of Action 401
Uses 401
Pharmacokinetics 401
Indications and Dosages 401
► Anxiety, Skeletal Muscle Relaxation 401
diclofenac 403
Category and Schedule 403
Drug Class: 403
Mechanism of Action 403
Uses 403
Pharmacokinetics 403
Indications and Dosages 403
► Osteoarthritis 403
dicloxacillin sodium 405
Category and Schedule 405
Drug Class: 405
Mechanism of Action 405
Uses 405
Pharmacokinetics 405
Indications and Dosage 405
► Respiratory Tract Infection, Staphylococcal and Streptococcal Infections 405
PO 405
Adults, Elderly, Children weighing more than 40 kg. 405
Children weighing less than 40 kg. 405
Side Effects/Adverse Reactions 405
Frequent 405
Occasional 406
Precautions and Contraindications 406
Caution: 406
Drug Interactions of Concern to Dentistry 406
Serious Reactions 406
Dental Considerations 406
General: 406
Consultations: 406
Teach Patient/Family to: 406
dicyclomine hydrochloride 406
Category and Schedule 406
Drug Class: 406
Mechanism of Action 406
Uses 406
Pharmacokinetics 406
Indications and Dosages 406
► Functional Disturbances of GI Motility 406
PO 406
Adults. 406
Children older than 2 yr. 407
Children 6 mo–2 yr. 407
Elderly. 407
IM 407
Side Effects/Adverse Reactions 407
Frequent 407
Occasional 407
Rare 407
Precautions and Contraindications 407
Caution: 407
Drug Interactions of Concern to Dentistry 407
Serious Reactions 407
Dental Considerations 407
General: 407
Consultation: 407
Teach Patient/Family to: 407
didanosine 408
Category and Schedule 408
Drug Class: 408
Mechanism of Action 408
Uses 408
Pharmacokinetics 408
Indications and Dosages 408
► HIV Infection (in combination with other antiretrovirals) 408
PO (Chewable Tablets) 408
diethylpropion 410
Category and Schedule 410
Drug Class: 410
Mechanism of Action 410
Uses 410
Pharmacokinetics 410
Indications and Dosages 410
► Obesity 410
PO 410
Adults. 410
Side Effects/Adverse Reactions 410
Frequent 410
Occasional 410
Rare 410
Precautions and Contraindications 410
Caution: 410
Drug Interactions of Concern to Dentistry 410
Serious Reactions 410
Dental Considerations 410
General: 410
Consultations: 411
Teach Patient/Family to: 411
diflorasone 411
Category and Schedule 411
Drug Class: 411
Mechanism of Action 411
Uses 411
Pharmacokinetics 411
Indications and Dosages 411
► Dermatoses 411
Topical 411
Adults, Elderly. 411
Side Effects/Adverse Reactions 411
Rare 411
Precautions and Contraindications 411
Caution: 411
Serious Reactions 412
Dental Considerations 412
General: 412
diflunisal 412
Category and Schedule 412
Drug Class: 412
Mechanism of Action 412
Uses 412
Pharmacokinetics 412
Indications and Dosages 412
► Mild-to-Moderate Pain 412
digoxin 414
Category and Schedule 414
Drug Class: 414
Mechanism of Action 414
Uses 414
Pharmacokinetics 414
Indications and Dosages 414
► Rapid Loading Dose for the Management and Treatment of CHF; Control of Ventricular Rate in Patients with Atrial Fibrillation; Treatment and Prevention of Recurrent Paroxysmal Atrial Tachycardia 414
PO 414
dihydrotachysterol 415
Category and Schedule 415
Drug Class: 415
Mechanism of Action 415
Uses 416
Pharmacokinetics 416
Indications and Dosages 416
► Hypoparathyroidism 416
diltiazem hydrochloride 417
Category and Schedule 417
Drug Class: 417
Mechanism of Action 417
Uses 417
Pharmacokinetics 417
Indications and Dosages 417
► Angina Related to Coronary Artery Spasm (Prinzmetal’s Variant), Chronic Stable Angina (Effort-Associated) 417
PO 417
dimenhydrinate 419
Category and Schedule 419
Drug Class: 419
Mechanism of Action 419
Uses 419
Pharmacokinetics 419
Indications and Dosages 419
► Motion Sickness 419
PO 419
Adults, Elderly, Children older than 12 yr. 419
Children 6–12 yr. 419
Children 2–5 yr. 419
Side Effects/Adverse Reactions 419
Frequent 419
Occasional 419
Rare 419
Precautions and Contraindications 419
Caution: 419
Drug Interactions of Concern to Dentistry 420
Serious Reactions 420
Dental Considerations 420
General: 420
Teach Patient/Family to: 420
dimethyl fumarate 420
Category and Schedule 420
Drug Class: 420
Mechanism of Action 420
Uses 420
Pharmacokinetics 420
Indications and Dosages 420
► Multiple Sclerosis 420
PO 420
Adults. 420
Side Effects/Adverse Reactions 420
Frequent 420
Occasional 420
Precautions and Contraindications 421
Drug Interactions of Concern to Dentistry 421
Serious Reactions 421
Dental Considerations 421
General: 421
Consultations: 421
Teach Patient/Family to: 421
diphenhydramine 421
Category and Schedule 421
Drug Class: 421
Mechanism of Action 421
Uses 422
Pharmacokinetics 422
Indications and Dosages 422
► Moderate to Severe Allergic Reaction, Dystonic Reaction 422
dipivefrin hydrochloride 423
Category and Schedule 423
Drug Class: 423
Mechanism of Action 423
Uses 423
Pharmacokinetics 423
Indications and Dosages 423
► Glaucoma, Open-Angle 423
Ophthalmic, Topical 423
Adults, Elderly. 423
Side Effects/Adverse Reactions 423
Occasional 423
dipyridamole 424
Category and Schedule 424
Drug Class: 424
Mechanism of Action 424
Uses 424
Pharmacokinetics 424
Indications and Dosages 424
► Prevention of Thromboembolic Disorders 424
PO 424
Adults, Elderly. 424
Children. 424
► Diagnostic Aid 424
IV 424
Adults, Elderly (based on weight). 424
Side Effects/Adverse Reactions 424
Frequent 424
Occasional 424
Rare 424
Precautions and Contraindications 424
Caution: 424
Drug Interactions of Concern to Dentistry 424
Serious Reactions 424
Dental Considerations 424
General: 424
Precautions and Contraindications 425
Caution: 425
Drug Interactions of Concern to Dentistry 425
Serious Reactions 425
Dental Considerations 425
General: 425
Consultations: 425
Teach Patient/Family to: 425
dirithromycin 425
Category and Schedule 425
Drug Class: 425
Mechanism of Action 425
Uses 425
Pharmacokinetics 425
Indications and Dosages 425
► Pharyngitis, Tonsillitis 425
disopyramide phosphate 426
Category and Schedule 426
Drug Class: 426
Mechanism of Action 426
Uses 426
Pharmacokinetics 427
Indications and Dosages 427
► Suppression and Prevention of Ventricular Ectopy, Unifocal or Multifocal Premature Ventricular Contractions, Paired Ventricular Contractions (Couplets), and Episodes of Ventricular Tachycardia 427
disulfiram 428
Category and Schedule 428
Drug Class: 428
Mechanism of Action 428
Uses 428
Pharmacokinetics 428
Indications and Dosages 429
► Adjunct in Management of Selected Chronic Alcoholic Patients Who Want to Remain in State of Enforced Sobriety 429
PO 429
Adults, Elderly. 429
Side Effects/Adverse Reactions 429
Frequent 429
Occasional 429
Precautions and Contraindications 429
Caution: 429
Drug Interactions of Concern to Dentistry 429
Serious Reactions 429
Dental Considerations 429
General: 429
Consultations: 429
Teach Patient/Family to: 429
dobutamine hydrochloride 429
Category and Schedule 429
Drug Class: 429
Mechanism of Action 429
docetaxel 430
Category and Schedule 430
Drug Class: 430
Mechanism of Action 430
Uses 430
Pharmacokinetics 430
Indications and Dosages 430
► Short-Term Management of Cardiac Decompensation 430
IV Infusion 430
Adults, Elderly, Children. 430
Neonates. 430
Side Effects/Adverse Reactions 430
Frequent 430
Occasional 430
Rare 430
Precautions and Contraindications 430
Drug Interactions of Concern to Dentistry 430
Serious Reactions 430
Dental Considerations 430
General: 430
Indications and Dosages 431
► Breast Carcinoma 431
docosanol 432
Category and Schedule 432
Drug Class: 432
Mechanism of Action 432
Uses 432
Pharmacokinetics 432
Indications and Dosages 432
► Recurrent Herpes Labialis 432
Topical 432
Adult, Children older than 12 yr. 432
Side Effects/Adverse Reactions 432
docusate 433
Category and Schedule 433
Drug Class: 433
Mechanism of Action 433
Uses 433
Pharmacokinetics 433
Indications and Dosages 433
► Stool Softener 433
PO 433
Adults, Elderly, Children 12 yr and older. 433
Children 6–11 yr. 433
Children 3–5 yr. 433
Children younger than 3 yr. 433
Side Effects/Adverse Reactions 433
Occasional 433
Rare 433
Precautions and Contraindications 433
Caution: 433
Drug Interactions of Concern to Dentistry 433
Dental Considerations 433
Teach Patient/Family to: 433
Serious Reactions 434
Dental Considerations 434
General: 434
dofetilide 434
Category and Schedule 434
Drug Class: 434
Mechanism of Action 434
Uses 434
Pharmacokinetics 434
Indications and Dosages 434
► Maintain Normal Sinus Rhythm after Conversion from Atrial Fibrillation or Flutter 434
PO 434
Adults, Elderly. 434
Side Effects/Adverse Reactions 434
Occasional 434
Precautions and Contraindications 434
Caution: 434
Drug Interactions of Concern to Dentistry 434
Serious Reactions 435
Dental Considerations 435
General: 435
Consultations: 435
Teach Patient/Family to: 435
dolasetron 435
Category and Schedule 435
Drug Class: 435
Mechanism of Action 435
Uses 435
Pharmacokinetics 435
Indications and Dosages 435
► Prevention of Chemotherapy-Induced Nausea and Vomiting 435
PO 435
Adults. 435
Children 2–16 yr. 435
IV 435
Adults, Children 1–16 yr. 435
► Treatment or Prevention of Postoperative Nausea or Vomiting 436
PO 436
donepezil hydrochloride 436
Category and Schedule 436
Drug Class: 436
Mechanism of Action 436
Uses 436
Pharmacokinetics 437
Indications and Dosages 437
► Alzheimer’s Disease 437
PO 437
Adults, Elderly. 437
Side Effects/Adverse Reactions 437
Frequent 437
Occasional 437
Rare 437
Precautions and Contraindications 437
Caution: 437
Drug Interactions of Concern to Dentistry 437
Serious Reactions 437
Dental Considerations 437
General: 437
Consultations: 438
Teach Patient/Family to: 438
doripenem 438
Category and Schedule 438
Drug Class: 438
Mechanism of Action 438
Uses 438
Pharmacokinetics 438
Indications and Dosages 438
► Complicated Intraabdominal Infection 438
dornase alfa 439
Category and Schedule 439
Drug Class: 439
Mechanism of Action 439
Uses 439
Pharmacokinetics 439
Indications and Dosages 439
► To Improve Management of Pulmonary Function in Patients with Cystic Fibrosis 439
Nebulization 439
Adults, Children older than 5 yr. 439
Side Effects/Adverse Reactions 439
Frequent 439
Occasional 439
Precautions and Contraindications 439
Caution: 439
Drug Interactions of Concern to Dentistry 439
Serious Reactions 439
Dental Considerations 439
General: 439
Consultations: 439
Teach Patient/Family to: 439
dorzolamide hydrochloride 440
Category and Schedule 440
Drug Class: 440
Mechanism of Action 440
Uses 440
Pharmacokinetics 440
Indications and Dosages 440
► Glaucoma, Ocular Hypertension 440
Ophthalmic 440
Adults, Elderly. 440
Side Effects/Adverse Reactions 440
Frequent 440
Occasional 440
Precautions and Contraindications 440
Caution: 440
Drug Interactions of Concern to Dentistry 440
Serious Reactions 440
Dental Considerations 440
General: 440
Consultations: 440
Teach Patient/Family to: 440
Consultations: 441
doxazosin mesylate 441
Category and Schedule 441
Drug Class: 441
Mechanism of Action 441
Uses 441
Pharmacokinetics 441
Indications and Dosages 441
► Mild-to-Moderate Hypertension 441
doxepin hydrochloride 442
Category and Schedule 442
Drug Class: 442
Mechanism of Action 442
Uses 442
Pharmacokinetics 442
Indications and Dosages 443
► Depression, Anxiety 443
PO 443
Adults. 443
Elderly. 443
Adolescents. 443
Children 12 yr and younger. 443
► Pruritus Associated with Eczema 443
Topical 443
Adults, Elderly. 443
Side Effects/Adverse Reactions 443
Frequent 443
Occasional 443
Rare 443
Precautions and Contraindications 443
Caution: 443
Drug Interactions of Concern to Dentistry FOR TOPICAL FORM 443
Drug Interactions of Concern to Dentistry FOR SYSTEMIC-DOSE FORM 443
Serious Reactions 443
Dental Considerations 444
► Topical Form 444
doxorubicin 445
Category and Schedule 445
Drug Class: 445
Mechanism of Action 445
Uses 445
Pharmacokinetics 445
Indications and Dosages 445
► AIDS-Related Kaposi’s Sarcoma 445
doxycycline 446
Category and Schedule 446
Drug Class: 446
Mechanism of Action 446
Uses 446
Pharmacokinetics 446
Indications and Dosages 447
► Respiratory, Skin, and Soft-Tissue Infections; UTIs; Pelvic Inflammatory Disease (PID); Brucellosis; Trachoma; Rocky Mountain Spotted Fever; Typhus; Q Fever; Rickettsia; Severe Acne (Adoxa); Smallpox; Psittacosis; Ornithosis; Granuloma Inguinale; Lymphogranuloma Venereum; Intestinal Amebiasis (Adjunctive Treatment); Prevention of Rheumatic Fever 447
doxycycline hyclate (dental-systemic) 448
Category and Schedule 448
Drug Class: 448
Mechanism of Action 448
Uses 448
Pharmacokinetics 448
Indications and Dosages 448
PO 448
Adult. 448
doxycycline hyclate gel 449
Category and Schedule 449
Drug Class: 449
Mechanism of Action 449
Uses 449
Pharmacokinetics 449
Indications and Dosages 449
Topical 449
Adult. 449
Side Effects/Adverse Reactions 449
Precautions and Contraindications 449
Caution: 449
Drug Interactions of Concern to Dentistry 449
Serious Reactions 449
Dental Considerations 449
General: 449
Teach Patient/Family to: 449
Precautions and Contraindications 450
Caution: 450
Drug Interactions of Concern to Dentistry 450
Serious Reactions 450
Dental Consideratons 450
General: 450
Teach Patient/Family to: 450
dronabinol 450
Category and Schedule 450
Drug Class: 450
Mechanism of Action 450
Uses 450
Pharmacokinetics 450
Indications and Dosages 450
► Prevention of Chemotherapy-Induced Nausea and Vomiting 450
PO 450
Adults, Children. 450
► Appetite Stimulant 451
PO 451
Adults. 451
Side Effects/Adverse Reactions 451
Frequent 451
Occasional 451
Rare 451
Precautions and Contraindications 451
Caution: 451
Drug Interactions of Concern to Dentistry 451
Serious Reactions 451
Dental Considerations 451
General: 451
Teach Patient/Family to: 451
dronedarone 452
Category and Schedule 452
Drug Class: 452
Mechanism of Action 452
Uses 452
Pharmacokinetics 452
Indications and Dosages 452
► Atrial Fibrillation 452
droperidol 453
Category and Schedule 453
Drug Class: 453
Mechanism of Action 453
Uses 454
Pharmacokinetics 454
Indications and Dosages 454
► Preoperative 454
IM/IV 454
dulaglutide 455
Category and Schedule 455
Drug Class: 455
Mechanism of Action 455
Uses 455
Pharmacokinetics 455
Indications and Dosages 455
► Type 2 Diabetes Mellitus 455
Adults. 455
Side Effects/Adverse Reactions 455
Frequent 455
Occasional 455
Precautions and Contraindications 455
Drug Interactions of Concern to Dentistry 455
Serious Reactions 456
Dental Considerations 456
General: 456
Consultations: 456
Teach Patient/Family to: 456
duloxetine 456
Category and Schedule 456
Drug Class: 456
Mechanism of Action 456
Uses 456
Pharmacokinetics 456
Indications and Dosages 456
► Depression 456
PO 456
Adult. 456
► Diabetic Peripheral Neuropathic Pain 457
PO 457
Adult. 457
Side Effects/Adverse Reactions 457
Precautions and Contraindications 457
Drug Interactions of Concern to Dentistry 457
Serious Reactions 457
Dental Considerations 457
General: 457
Consultations: 457
Teach Patient/Family to: 457
dutasteride 458
Category and Schedule 458
Drug Class: 458
Mechanism of Action 458
Uses 458
Pharmacokinetics 458
Indications and Dosages 458
► BPH 458
PO 458
Adults, Elderly. 458
Side Effects/Adverse Reactions 458
Occasional 458
Precautions and Contraindications 458
Caution: 458
Drug Interactions of Concern to Dentistry 458
Serious Reactions 458
Dental Considerations 458
General: 458
Consultations: 458
Teach Patient/Family to: 458
dutasteride + tamsulosin 459
Category and Schedule 459
Drug Class: 459
Mechanism of Action 459
Uses 459
Pharmacokinetics 459
Indications and Dosages 459
► Benign Prostatic Hyperplasia (BPH) 459
PO 459
Adults. 459
Side Effects/Adverse Reactions 459
Frequent 459
Occasional 459
Precautions and Contraindications 459
Drug Interactions of Concern to Dentistry 459
Serious Reactions 460
Dental Considerations 460
General: 460
dyphylline 460
Category and Schedule 460
Drug Class: 460
Mechanism of Action 460
Uses 460
Pharmacokinetics 460
Indications and Dosages 460
► Chronic Bronchospasm, Asthma 460
PO 460
echothiophate iodide 462
Category and Schedule 462
Drug Class: 462
Mechanism of Action 462
Uses 462
Pharmacokinetics 462
Indications and Dosages 462
► Glaucoma 462
edoxaban 463
Category and Schedule 463
Drug Class: 463
Mechanism of Action 463
Uses 463
Pharmacokinetics 463
Indications and Dosages 463
► Deep Vein Thrombosis and Pulmonary Embolism 463
efavirenz 464
Category and Schedule 464
Drug Class: 464
Mechanism of Action 464
Uses 464
Pharmacokinetics 464
Indications and Dosages 464
► HIV Infection (in Combination with Other Antiretrovirals) 464
PO 464
Adults, Elderly, Children 3 yr and older weighing 40 kg or more. 464
Children 3 yr and older weighing 32.5 kg to less than 40 kg. 464
Children 3 yr and older weighing 25 kg to less than 32.5 kg. 465
Children 3 yr and older weighing 20 kg to less than 25 kg. 465
Children 3 yr and older weighing 15 kg to less than 20 kg. 465
Children 3 yr and older weighing 10 kg to less than 15 kg. 465
Side Effects/Adverse Reactions 465
Frequent 465
Occasional 465
Precautions and Contraindications 465
Caution: 465
Drug Interactions of Concern to Dentistry 465
Serious Reactions 465
Dental Considerations 465
General: 465
Consultations: 465
Teach Patient/Family to: 465
efinaconazole 466
Category and Schedule 466
Drug Class: 466
Mechanism of Action 466
Uses 466
Pharmacokinetics 466
Indications and Dosages 466
► Onychomycosis 466
Adults. 466
Side Effects/Adverse Reactions 466
Frequent 466
Occasional 466
Precautions and Contraindications 466
Drug Interactions of Concern to Dentistry 466
Serious Reactions 466
Dental Considerations 466
General: 466
Teach Patient/Family to: 466
Uses 467
Pharmacokinetics 467
Indications and Dosages 467
► Acute Migraine Headache 467
PO 467
Adults, Elderly. 467
Side Effects/Adverse Reactions 467
Occasional 467
Rare 467
Precautions and Contraindications 467
Caution: 467
Drug Interactions of Concern to Dentistry 467
Serious Reactions 467
Dental Considerations 467
General: 467
Consultations: 467
Teach Patient/Family to: 467
eletriptan 466
eliglustat 468
Category and Schedule 468
Drug Class: 468
Mechanism of Action 468
Uses 468
Pharmacokinetics 468
Indications and Dosages 468
► Gaucher’S Disease, Type 1 468
PO 468
Adults. 468
Side Effects/Adverse Reactions 468
Frequent 468
Occasional 468
Precautions and Contraindications 468
Drug Interactions of Concern to Dentistry 468
Serious Reactions 469
Dental Considerations 469
General: 469
Consultations: 469
Teach Patient/Family to: 469
eluxadoline 469
Category and Schedule 469
Drug Class: 469
Mechanism of Action 469
Uses 469
Pharmacokinetics 469
Indications and Dosages 469
► Irritable Bowel Syndrome With Diarrhea 469
PO 469
Adults. 469
Side Effects/Adverse Reactions 469
Frequent 469
Occasional 469
Precautions and Contraindications 469
Drug Interactions of Concern to Dentistry 470
Serious Reactions 470
Dental Considerations 470
General: 470
Consultations: 470
Teach Patient/Family to: 470
emedastine 470
Category and Schedule 470
Drug Class: 470
Mechanism of Action 470
Uses 470
Pharmacokinetics 470
Indications and Dosages 470
► Allergic Conjunctivitis 470
Ophthalmic 470
Adults, Elderly, Children 3 yr and older. 470
Side Effects/Adverse Reactions 470
Frequent 470
Occasional 470
empagliflozin 471
Category and Schedule 471
Drug Class: 471
Mechanism of Action 471
Uses 471
Pharmacokinetics 471
Indications and Dosages 471
► Type 2 Diabetes Mellitus 471
PO 471
Adults. 471
Side Effects/Adverse Reactions 471
Frequent 471
Occasional 471
Precautions and Contraindications 471
Caution: 471
Drug Interactions of Concern to Dentistry 471
Serious Reactions 471
Serious Reactions 472
Dental Considerations 472
General: 472
Consultations: 472
Teach Patient/Family to: 472
emtricitabine 472
Category and Schedule 472
Drug Class: 472
Mechanism of Action 472
Uses 472
Pharmacokinetics 472
Indications and Dosages 472
► HIV Infection (in Combination with Other Antiretrovirals) 472
PO 472
Adults, Elderly. 472
► Dosage in Renal Impairment 472
Side Effects/Adverse Reactions 473
Frequent 473
Occasional 473
Rare 473
Precautions and Contraindications 473
Caution: 473
Drug Interactions of Concern to Dentistry 473
Serious Reactions 473
Dental Considerations 473
General: 473
Consultations: 473
Teach Patient/Family to: 473
emtricitabine + rilpivirine + tenofovir disoproxil 473
Category and Schedule 473
Drug Class: 473
Mechanism of Action 473
Uses 474
Pharmacokinetics 474
Indications and Dosages 474
▸ HIV 474
PO 474
Adults. 474
Side Effects/Adverse Reactions 474
Frequent 474
Occasional 474
Precautions and Contraindications 474
Drug Interactions of Concern to Dentistry 474
Serious Reactions 474
Dental Considerations 474
General: 474
Teach Patient/Family to: 475
enalapril maleate 475
Category and Schedule 475
Drug Class: 475
Mechanism of Action 475
Uses 475
Pharmacokinetics 475
Indications and Dosages 475
► Hypertension Alone or in Combination with Other Antihypertensives 475
enfuvirtide 477
Category and Schedule 477
Drug Class: 477
Mechanism of Action 477
Uses 477
Pharmacokinetics 477
Indications and Dosages 477
► HIV Infection (in combination with other antiretrovirals) 477
Subcutaneous 477
Adults, Elderly. 477
Children 6–16 yr. 477
Pediatric dosing guidelines 477
Side Effects/Adverse Reactions 477
Expected 477
Frequent 477
Occasional 477
Rare 477
Precautions and Contraindications 477
Drug Interactions of Concern to Dentistry 478
Serious Reactions 478
Dental Considerations 478
General: 478
Consultations: 478
Teach Patient/Family to: 478
enoxaparin sodium 478
Category and Schedule 478
Drug Class: 478
Mechanism of Action 478
Uses 478
Pharmacokinetics 478
Indications and Dosages 479
► Prevention of DVT after Hip and Knee Surgery 479
entacapone 480
Category and Schedule 480
Drug Class: 480
Mechanism of Action 480
Uses 480
Pharmacokinetics 480
Indications and Dosages 480
► Adjunctive Treatment of Parkinson’s Disease 480
PO 480
Adults, Elderly. 480
Side Effects/Adverse Reactions 480
Frequent 480
Occasional 480
Rare 480
Precautions and Contraindications 480
Caution: 480
Drug Interactions of Concern to Dentistry 480
Serious Reactions 481
Dental Considerations 481
General: 481
Consultations: 481
Teach Patient/Family to: 481
ephedrine 481
Category and Schedule 481
Drug Class: 481
Mechanism of Action 481
Uses 481
Pharmacokinetics 481
Indications and Dosages 482
► Asthma 482
epinastine 483
Category and Schedule 483
Drug Class: 483
Mechanism of Action 483
Uses 483
Pharmacokinetics 483
Indications and Dosages 483
► Allergic Conjunctivitis 483
Ophthalmic 483
Adults, Elderly, Children 3 yr and older. 483
Side Effects/Adverse Reactions 483
Occasional 483
Rare 483
Precautions and Contraindications 483
Caution: 483
Drug Interactions of Concern to Dentistry 483
Serious Reactions 483
Dental Considerations 484
General: 484
epinephrine 484
Category and Schedule 484
Drug Class: 484
Mechanism of Action 484
Uses 484
Pharmacokinetics 484
Indications and Dosages 484
► Asystole 484
epinephryl borate 486
Category and Schedule 486
Drug Class: 486
Mechanism of Action 486
Uses 486
Pharmacokinetics 486
Indications and Dosages 486
► Glaucoma 486
Ophthalmic 486
Adults, Elderly. 486
Side Effects/Adverse Reactions 486
Frequent 486
Occasional 486
Precautions and Contraindications 486
Drug Interactions of Concern to Dentistry 486
Serious Reactions 486
Dental Considerations 486
General: 486
Consultations: 487
Teach Patient/Family to: 487
epirubicin 487
Category and Schedule 487
Drug Class: 487
Mechanism of Action 487
Uses 487
Pharmacokinetics 487
Indications and Dosages 487
► Breast Cancer 487
IV 487
Adults. 487
Side Effects/Adverse Reactions 487
Frequent 487
Occasional 487
Rare 487
Precautions and Contraindications 487
Drug Interactions of Concern to Dentistry 487
Serious Reactions 487
Dental Considerations 488
General: 488
Consultations: 488
Teach Patient/Family to: 488
eplerenone 488
Category and Schedule 488
Drug Class: 488
Mechanism of Action 488
Uses 489
Pharmacokinetics 489
Indications and Dosages 489
► Hypertension 489
epoetin alfa 490
Category and Schedule 490
Drug Class: 490
Mechanism of Action 490
Uses 490
Pharmacokinetics 490
Indications and Dosages 490
► Treatment of Anemia in Chemotherapy Patients 490
epoprostenol sodium, prostacyclin 492
Category and Schedule 492
Drug Class: 492
Mechanism of Action 492
Uses 492
Indications and Dosages 492
► Long-Term Treatment of New York Heart Association Class III and IV Primary Pulmonary Hypertension 492
IV Infusion 492
Adults, Elderly. 492
Side Effects/Adverse Reactions 492
Frequent 492
Occasional 492
Rare 492
Precautions and Contraindications 492
Drug Interactions of Concern to Dentistry 492
Serious Reactions 493
Dental Considerations 493
General: 493
Consultations: 493
Teach Patient/Family to: 493
eprosartan 493
Category and Schedule 493
Drug Class: 493
Mechanism of Action 493
Uses 493
Pharmacokinetics 493
Indications and Dosages 494
► Hypertension 494
PO 494
Adults, Elderly. 494
Side Effects/Adverse Reactions 494
Occasional 494
Rare 494
Precautions and Contraindications 494
Caution: 494
Drug Interactions of Concern to Dentistry 494
Serious Reactions 494
Dental Considerations 494
General: 494
Consultations: 494
Teach Patient/Family to: 494
eptifibatide 494
Category and Schedule 494
Drug Class: 494
Mechanism of Action 495
Uses 495
Pharmacokinetics 495
Indications and Dosages 495
4Adjunct to Percutaneous Coronary Intervention 495
ergoloid mesylates 496
Category and Schedule 496
Drug Class: 496
Mechanism of Action 496
Uses 496
Pharmacokinetics 496
Indications and Dosages 496
► Age-Related Decline in Mental Capacity 496
PO 496
Adults, Elderly. 496
Side Effects/Adverse Reactions 496
Occasional 496
Precautions and Contraindications 496
Caution: 496
Serious Reactions 496
Dental Considerations 497
General: 497
Teach Patient/Family to: 497
ergotamine tartrate/dihydroergotamine 497
Category and Schedule 497
Drug Class: 497
Mechanism of Action 497
Uses 497
Pharmacokinetics 497
Indications and Dosages 497
► Vascular Headaches 497
PO (Cafergot [Fixed-Combination of Ergotamine and Caffeine]) 497
erlotinib 498
Category and Schedule 498
Drug Class: 498
Mechanism of Action 498
Uses 498
Pharmacokinetics 499
Indications and Dosages 499
► Non–Small-Cell Lung Pancreatic Cancer 499
PO 499
Adults, Elderly. 499
Side Effects/Adverse Reactions 499
Frequent 499
Occasional 499
Rare 499
Precautions and Contraindications 499
Drug Interactions of Concern to Dentistry 499
Serious Reactions 499
Dental Considerations 499
General: 499
Consultations: 499
Teach Patient/Family to: 499
ertapenem 500
Category and Schedule 500
Drug Class: 500
Mechanism of Action 500
Uses 500
Pharmacokinetics 500
Indications and Dosages 500
► Intraabdominal Infection 500
erythromycin 501
Category and Schedule 501
Drug Class: 501
Mechanism of Action 501
Uses 501
Pharmacokinetics 501
Indications and Dosages 501
► Mild-to-Moderate Infections of the Upper and Lower Respiratory Tract, Pharyngitis, Skin Infections 501
escitalopram 503
Category and Schedule 503
Drug Class: 503
Mechanism of Action 503
Uses 503
Pharmacokinetics 503
Indications and Dosages 503
► Depression, General Anxiety Disorder (GAD) 503
PO 503
Adults. 503
Elderly. 503
Side Effects/Adverse Reactions 503
Frequent 503
Occasional 503
Rare 503
Precautions and Contraindications 503
Caution: 503
Drug Interactions of Concern to Dentistry 503
Serious Reactions 504
Dental Considerations 504
General: 504
Consultations: 504
Teach Patient/Family to: 504
esomeprazole 504
Category and Schedule 504
Drug Class: 504
Mechanism of Action 504
Uses 504
Pharmacokinetics 504
Indications and Dosages 505
► Erosive Esophagitis 505
estazolam 506
Category and Schedule 506
Drug Class: 506
Mechanism of Action 506
Uses 506
Pharmacokinetics 506
Indications and Dosages 506
► Insomnia 506
PO 506
Adults (older than 18 yr). 506
Elderly, debilitated, liver disease, low serum albumin. 506
Side Effects/Adverse Reactions 506
Frequent 506
Occasional 506
Rare 506
Precautions and Contraindications 506
Caution: 506
Drug Interactions of Concern to Dentistry 506
Serious Reactions 506
Dental Considerations 507
General: 507
Teach Patient/Family to: 507
estradiol 507
Category and Schedule 507
Drug Class: 507
Mechanism of Action 507
Uses 507
Pharmacokinetics 507
Indications and Dosages 507
► Prostate Cancer 507
IM (Estradiol Valerate) 507
estradiol valerate + dienogest 509
Category and Schedule 509
Drug Class: 509
Mechanism of Action 509
Uses 509
Pharmacokinetics 509
Indications and Dosages 509
▸ Contraception or Treatment of Heavy Menstrual Bleeding 509
PO 509
Adults (Females). 509
Side Effects/Adverse Reactions 509
Frequent 509
Occasional 509
Precautions and Contraindications 509
Drug Interactions of Concern to Dentistry 510
Serious Reactions 510
Dental Considerations 510
General: 510
estramustine phosphate sodium 510
Category and Schedule 510
Drug Class: 510
Mechanism of Action 510
Uses 510
Pharmacokinetics 510
Indications and Dosages 510
► Prostatic Carcinoma 510
PO 510
Adults, Elderly. 510
Side Effects/Adverse Reactions 510
Frequent 510
Occasional 511
Rare 511
Precautions and Contraindications 511
Drug Interactions of Concern to Dentistry 511
Serious Reactions 511
Dental Considerations 511
General: 511
Consultations: 511
Teach Patient/Family to: 511
estrogens, conjugated; medroxyprogesterone acetate 511
Category and Schedule 511
Drug Class: 511
Mechanism of Action 511
Uses 512
Pharmacokinetics 512
Indications and Dosages 512
estropipate 513
Category and Schedule 513
Drug Class: 513
Mechanism of Action 513
Uses 513
Pharmacokinetics 513
Indications and Dosages 513
► Vasomotor Symptoms, Atrophic Vaginitis, Kraurosis Vulvae 513
eszopiclone 514
Category and Schedule 514
Drug Class: 514
Mechanism of Action 514
Uses 514
Pharmacokinetics 514
Indications and Dosages 515
► Insomnia 515
PO 515
Adult. 515
Side Effects/Adverse Reactions 515
Precautions and Contraindications 515
Drug Interactions of Concern to Dentistry 515
Dental Considerations 515
General: 515
Consultations: 515
Teach Patient/Family: 515
etanercept 515
Category and Schedule 515
Drug Class: 515
Mechanism of Action 515
Uses 516
Pharmacokinetics 516
Indications and Dosages 516
► Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis 516
ethambutol 517
Category and Schedule 517
Drug Class: 517
Mechanism of Action 517
Uses 517
Pharmacokinetics 517
Indications and Dosages 517
► TB 517
ethionamide 518
Category and Schedule 518
Drug Class: 518
Mechanism of Action 518
Uses 518
Pharmacokinetics 518
Indications and Dosages 518
► TB 518
PO 518
Adults, Elderly. 518
Children. 518
► Dosage in Renal Impairment 518
Side Effects/Adverse Reactions 518
Occasional 518
Rare 518
Precautions and Contraindications 518
Caution: 519
Drug Interactions of Concern to Dentistry 519
Serious Reactions 519
Dental Considerations 519
General: 519
Consultations: 519
Teach Patient/Family to: 519
ethosuximide 519
Category and Schedule 519
Drug Class: 519
Mechanism of Action 519
Uses 519
Pharmacokinetics 519
Indications and Dosages 519
► Absence Seizures 519
PO 519
Adults, Elderly, Children older than 6 yr. 519
Children 3–6 yr. 520
Side Effects/Adverse Reactions 520
Occasional 520
Rare 520
Precautions and Contraindications 520
Caution: 520
Drug Interactions of Concern to Dentistry 520
Serious Reactions 520
Dental Considerations 520
General: 520
Consultations: 520
Teach Patient/Family to: 520
etidronate disodium 520
Category and Schedule 520
Drug Class: 520
Mechanism of Action 520
Uses 520
Pharmacokinetics 521
Indications and Dosages 521
► Paget’s Disease 521
etodolac 521
Category and Schedule 521
Drug Class: 521
Mechanism of Action 522
Uses 522
Pharmacokinetics 522
Indications and Dosages 522
► Osteoarthritis, Rheumatoid Arthritis 522
PO (Immediate-Release) 522
etoposide, VP-16 523
Category and Schedule 523
Drug Class: 523
Mechanism of Action 523
Uses 523
Pharmacokinetics 523
Indications and Dosages 524
► Refractory Testicular Tumors 524
etravirine 525
Category and Schedule 525
Drug Class: 525
Mechanism of Action 525
Uses 525
Pharmacokinetics 525
Indications and Dosages 525
PO 525
Adult. 525
Side Effects/Adverse Reactions 526
Frequent 526
Occasional 526
Precautions and Contraindications 526
Drug Interactions of Concern to Dentistry 526
Serious Reactions 526
Dental Considerations 526
General: 526
Consultations: 526
Teach Patient/Family to: 526
everolimus 527
Category and Schedule 527
Drug Class: 527
Mechanism of Action 527
Uses 527
Pharmacokinetics 527
Indications and Dosages 527
► Breast Cancer, Advanced, Hormone Receptor-Positive, HER2-Negative 527
exemestane 529
Category and Schedule 529
Drug Class: 529
Mechanism of Action 529
Uses 529
Pharmacokinetics 529
Indications and Dosages 529
► Breast Cancer 529
PO 529
Adults, Elderly. 529
Side Effects/Adverse Reactions 529
Frequent 529
Occasional 530
Rare 530
Precautions and Contraindications 530
Drug Interactions of Concern to Dentistry 530
Serious Reactions 530
Dental Considerations 530
General: 530
Consultations: 530
Teach Patient/Family to: 530
exenatide 530
Category and Schedule 530
Drug Class: 530
Mechanism of Action 530
Uses 530
Pharmacokinetics 530
Indications and Dosages 530
► Treatment of Type 2 Diabetes Mellitus (NIDDM), Adjunct or Monotherapy 530
SC 530
Adults. 530
Side Effects/Adverse Reactions 531
Frequent 531
Occasional 531
Precautions and Contraindications 531
Caution: 531
Drug Interactions of Concern to Dentistry 531
Serious Reactions 531
Dental Considerations 531
General: 531
Consultations: 531
Teach Patient/Family to: 531
ezetimibe 531
Category and Schedule 531
Drug Class: 531
Mechanism of Action 532
Uses 532
Pharmacokinetics 532
Indications and Dosages 532
► Hypercholesterolemia 532
PO 532
Adults, Elderly. 532
Side Effects/Adverse Reactions 532
Occasional 532
Precautions and Contraindications 532
Caution: 532
Drug Interactions of Concern to Dentistry 532
Serious Reactions 532
Dental Considerations 532
General: 532
Consultations: 532
Teach Patient/Family to: 532
ezogabine 533
Category and Schedule 533
Drug Class: 533
Mechanism of Action 533
Uses 533
Pharmacokinetics 533
Indications and Dosages 533
► Partial-Onset Seizures, Adjunct 533
PO 533
Adults. 533
Elderly. 533
► Renal Impairment 533
► Hepatic Impairment 533
Side Effects/Adverse Reactions 533
Frequent 533
Occasional 533
Precautions and Contraindications 533
Drug Interactions of Concern to Dentistry 533
Serious Reactions 534
Dental Considerations 534
General: 534
Consultations: 534
Teach Patient/Family to: 534
famciclovir 535
Category and Schedule 535
Drug Class: 535
Mechanism of Action 535
Uses 535
Pharmacokinetics 535
Indications and Dosages 535
► Herpes Zoster 535
famotidine 536
Category and Schedule 536
Drug Class: 536
Mechanism of Action 536
Uses 536
Pharmacokinetics 536
Indications and Dosages 536
► Acute Treatment of Duodenal and Gastric Ulcers 536
febuxostat 537
Category and Schedule 537
Drug Class: 537
Mechanism of Action 538
Uses 538
Pharmacokinetics 538
Indications and Dosages 538
► Hyperuricemia in Patients with Gout 538
PO 538
Adults. 538
Side Effects/Adverse Reactions 538
Rare (≤1%) 538
Precautions and Contraindications 538
Caution: 538
Drug Interactions of Concern to Dentistry 538
Serious Reactions 538
Dental Considerations 538
General: 538
Consultations: 538
Teach Patient/Family to: 538
felbamate 539
Category and Schedule 539
Drug Class: 539
Mechanism of Action 539
Uses 539
Pharmacokinetics 539
Indications and Dosages 539
► Monotherapy or Adjunctive Therapy in the Treatment of Partial Seizures, with and without Generalization 539
felodipine 540
Category and Schedule 540
Drug Class: 540
Mechanism of Action 540
Uses 541
Pharmacokinetics 541
Indications and Dosages 541
► Hypertension 541
PO 541
Adults. 541
Elderly, Patients with impaired hepatic function. 541
Side Effects/Adverse Reactions 541
Frequent 541
Occasional 541
Rare 541
Precautions and Contraindications 541
Caution: 541
Drug Interactions of Concern to Dentistry 541
Serious Reactions 541
Dental Considerations 541
General: 541
Consultations: 542
Teach Patient/Family to: 542
fenofibrate 542
Category and Schedule 542
Drug Class: 542
Mechanism of Action 542
Uses 542
Pharmacokinetics 542
Indications and Dosages 542
► Reduction of Very High Serum Triglyceride Levels in Patients at Risk for Pancreatitis 542
fenoprofen calcium 543
Category and Schedule 543
Drug Class: 543
Mechanism of Action 543
Uses 543
Pharmacokinetics 543
Indications and Dosages 544
► Mild-to-Moderate Pain 544
fentanyl, buccal 545
Category and Schedule 545
Drug Class: 545
Mechanism of Action 545
Uses 545
Pharmacokinetics 545
Indications and Dosages 545
► Chronic Pain 545
Transmucosal form 545
Adults. 545
Side Effects/Adverse Reactions 545
Frequent 545
Occasional 545
Precautions and Contraindications 545
Drug Interactions of Concern to Dentistry 545
Serious Reactions 545
Dental Considerations 546
General: 546
Teach Patient/Family to: 546
fentanyl transdermal system 546
Category and Schedule 546
Drug Class: 546
Mechanism of Action 546
Uses 546
Pharmacokinetics 546
Indications and Dosages 546
► Chronic Pain 546
Topical 546
ferric citrate 547
Category and Schedule 547
Drug Class: 547
Mechanism of Action 547
Uses 547
Pharmacokinetics 547
Indications and Dosages 548
► Hyperphosphatemia 548
PO 548
Adults. 548
Side Effects/Adverse Reactions 548
Frequent 548
Occasional 548
Precautions and Contraindications 548
Drug Interactions of Concern to Dentistry 548
Serious Reactions 548
Dental Considerations 548
General: 548
Consultations: 548
Teach Patient/Family to: 548
fesoterodine 548
Category and Schedule 548
Drug Class: 548
Mechanism of Action 548
Uses 548
Pharmacokinetics 548
Indications and Dosages 549
► Overactive Bladder 549
PO 549
Adults. 549
Side Effects/Adverse Reactions 549
Frequent 549
Occasional 549
Precautions and Contraindications 549
Caution: 549
Drug Interactions of Concern to Dentistry 549
Serious Reactions 549
Dental Considerations 549
General: 549
Consultations: 549
Teach Patient/Family to: 549
fexofenadine hydrochloride 550
fidaxomicin 550
Category and Schedule 550
Drug Class: 550
Mechanism of Action 550
Uses 550
Pharmacokinetics 550
Indications and Dosages 550
► Allergic Rhinitis, Urticaria 550
PO 550
Adults, Elderly, Children 12 yr and older. 550
filgrastim 551
Category and Schedule 551
Drug Class: 551
Mechanism of Action 551
Uses 551
Pharmacokinetics 551
Indications and Dosages 551
► Treatment of Clostridium Difficile-Associated Diarrhea (CDAD) 551
PO 551
Adults. 551
Side Effects/Adverse Reactions 551
Frequent 551
Occasional 551
Precautions and Contraindications 551
Drug Interactions of Concern to Dentistry 551
Serious Reactions 551
Dental Considerations 551
General: 551
Teach Patient/Family to: 551
Indications and Dosages 552
► Myelosuppression 552
IV or Subcutaneous Infusion, Subcutaneous Injection 552
finafloxacin 553
Category and Schedule 553
Drug Class: 553
Mechanism of Action 553
Uses 553
Pharmacokinetics 553
Indications and Dosages 553
► Acute Otitis Externa 553
Children 1 yr and older and adults. 553
Side Effects/Adverse Reactions 553
Frequent 553
Occasional 553
Precautions and Contraindications 553
Drug Interactions of Concern to Dentistry 553
Serious Reactions 553
finasteride 554
Category and Schedule 554
Drug Class: 554
Mechanism of Action 554
Uses 554
Pharmacokinetics 554
Indications and Dosages 554
► BPH 554
fingolimod 555
Category and Schedule 555
Drug Class: 555
Mechanism of Action 555
Uses 555
Pharmacokinetics 555
Indications and Dosages 555
► Multiple Sclerosis 555
PO 555
Adults. 555
Side Effects/Adverse Reactions 555
Frequent 555
Occasional 555
Precautions and Contraindications 555
Drug Interactions of Concern to Dentistry 555
Serious Reactions 555
Dental Considerations 555
General: 555
Consultations: 556
Teach Patient/Family to: 556
flavoxate 556
Category and Schedule 556
Drug Class: 556
Mechanism of Action 556
Uses 556
Pharmacokinetics 556
Indications and Dosages 556
► To Relieve Symptoms of Cystitis, Prostatitis, Urethritis, Urethrocystitis, or Urethrotrigonitis 556
PO 556
Adults, Elderly, Adolescents. 556
Side Effects/Adverse Reactions 556
Frequent 556
Occasional 556
Rare 556
Precautions and Contraindications 556
Caution: 556
Drug Interactions of Concern to Dentistry 556
Serious Reactions 556
Dental Considerations 557
General: 557
Teach Patient/Family to: 557
flecainide 557
Category and Schedule 557
Drug Class: 557
Mechanism of Action 557
Uses 557
Pharmacokinetics 557
Indications and Dosages 557
► Life-Threatening Ventricular Arrhythmias, Sustained Ventricular Tachycardia 557
flibanserin 558
Category and Schedule 558
Drug Class: 558
Mechanism of Action 558
Uses 558
Pharmacokinetics 558
Indications and Dosages 558
► Hypoactive Sexual Desire Disorder (Females—Premenopausal) 558
PO 558
Adults. 558
Side Effects/Adverse Reactions 559
Frequent 559
Occasional 559
Precautions and Contraindications 559
Drug Interactions of Concern to Dentistry 559
Serious Reactions 559
Dental Considerations 559
General: 559
Consultations: 559
Teach Patient/Family to: 559
fluconazole 559
Category and Schedule 559
Drug Class: 559
Mechanism of Action 560
Uses 560
Pharmacokinetics 560
Indications and Dosages 560
► Oropharyngeal Candidiasis 560
flucytosine 561
Category and Schedule 561
Drug Class: 561
Mechanism of Action 561
Uses 561
Pharmacokinetics 562
Indications and Dosages 562
► Fungal Infections, Candidiasis, Cryptococcosis 562
PO 562
Adults, Elderly, Children. 562
► Dosage in Renal Function Impairment 562
Side Effects/Adverse Reactions 562
Occasional 562
Precautions and Contraindications 562
Caution: 562
Drug Interactions of Concern to Dentistry 562
Serious Reactions 562
Dental Considerations 562
General: 562
Consultations: 562
Teach Patient/Family to: 562
fludarabine phosphate 562
Category and Schedule 562
Drug Class: 562
Mechanism of Action 563
Uses 563
Pharmacokinetics 563
Indications and Dosages 563
► Chronic Lymphocytic Leukemia 563
fludrocortisone 564
Category and Schedule 564
Drug Class: 564
Mechanism of Action 564
Uses 564
Pharmacokinetics 564
Indications and Dosages 564
► Addison’s Disease 564
PO 564
Adults, Elderly. 564
► Salt-Losing Adrenogenital Syndrome 565
PO 565
Adults, Elderly. 565
Usual Pediatric Dosage 565
Children. 565
Side Effects/Adverse Reactions 565
Frequent 565
Occasional 565
Rare 565
Precautions and Contraindications 565
Caution: 565
Drug Interactions of Concern to Dentistry 565
Serious Reactions 565
Dental Considerations 565
General: 565
Consultations: 566
Teach Patient/Family to: 566
flumazenil 566
Category and Schedule 566
Drug Class: 566
Mechanism of Action 566
Uses 566
Pharmacokinetics 566
Indications and Dosages 566
► Reversal of Conscious Sedation or General Anesthesia 566
flunisolide 567
Category and Schedule 567
Drug Class: 567
Mechanism of Action 567
Uses 567
Pharmacokinetics 567
Indications and Dosages 567
► Long-Term Control of Bronchial Asthma, Assists in Reducing or Discontinuing Oral Corticosteroid Therapy 567
Inhalation 567
Adults, Elderly. 567
Children 6–15 yr. 567
► Relief of Symptoms of Perennial and Seasonal Rhinitis 568
Intranasal 568
Adults, Elderly. 568
Children 6–14 yr. 568
Side Effects/Adverse Reactions 568
Frequent 568
Occasional 568
Precautions and Contraindications 568
Caution: 568
Serious Reactions 568
Dental Considerations 568
General: 568
Consultations: 568
Teach Patient/Family to: 568
fluocinolone acetonide 569
Category and Schedule 569
Drug Class: 569
Mechanism of Action 569
Uses 569
Pharmacokinetics 569
Indications and Dosages 569
► Atopic Dermatitis 569
fluocinonide 570
Category and Schedule 570
Drug Class: 570
Mechanism of Action 570
Uses 570
Pharmacokinetics 570
Indications and Dosages 570
► Dermatoses 570
Topical 570
Adults, Elderly. 570
Side Effects/Adverse Reactions 570
Occasional 570
Rare 570
Precautions and Contraindications 570
Caution: 570
Drug Interactions of Concern to Dentistry 570
Serious Reactions 570
Dental Considerations 570
General: 570
Teach Patient/Family to: 570
fluorouracil, 5FU 571
Category and Schedule 571
Drug Class: 571
Mechanism of Action 571
Uses 571
Pharmacokinetics 571
Indications and Dosages 571
► Carcinoma of Breast, Colon, Pancreas, Rectum, and Stomach; in Combination with Levamisole after Surgical Resection in Patients with Duke’s Stage C Colon Cancer 571
IV 571
Adults, Elderly, Children. 571
► Multiple Actinic or Solar Keratoses 571
Topical (Carac) 571
fluoxetine hydrochloride 572
Category and Schedule 572
Drug Class: 572
Mechanism of Action 572
Uses 572
Pharmacokinetics 572
Indications and Dosages 572
► Depression, Obsessive-Compulsive Disorder 572
PO 572
Adults. 572
Elderly. 572
Children 7–17 yr. 572
► Panic Disorder 573
fluoxymesterone 574
Category and Schedule 574
Drug Class: 574
Mechanism of Action 574
Uses 574
Pharmacokinetics 574
Indications and Dosages 574
► Males (Hypogonadism) 574
fluphenazine decanoate 575
Category and Schedule 575
Drug Class: 575
Mechanism of Action 575
Uses 575
Pharmacokinetics 575
Indications and Dosages 575
► Psychotic Disorders 575
flurandrenolide 577
Category and Schedule 577
Drug Class: 577
Mechanism of Action 577
Uses 577
Pharmacokinetics 577
Indications and Dosages 577
► Antiinflammatory, Immunosuppressant, Corticosteroid Replacement Therapy 577
Topical 577
Adults, Elderly. 577
Children. 577
Side Effects/Adverse Reactions 577
Occasional 577
Rare 577
Precautions and Contraindications 577
Caution: 578
Drug Interactions of Concern to Dentistry 578
Serious Reactions 578
Dental Considerations 578
General: 578
flurazepam hydrochloride 578
Category and Schedule 578
Drug Class: 578
Mechanism of Action 578
Uses 578
Pharmacokinetics 578
Indications and Dosages 578
► Insomnia 578
PO 578
Adults. 578
Elderly, debilitated, liver disease, low serum albumin, Children 15 yr and older. 578
Side Effects/Adverse Reactions 578
Frequent 578
Occasional 578
Rare 578
Precautions and Contraindications 578
Caution: 579
Drug Interactions of Concern to Dentistry 579
Serious Reactions 579
Dental Considerations 579
General: 579
Consultations: 579
Teach Patient/Family to: 579
flurbiprofen 579
Category and Schedule 579
Drug Class: 579
Mechanism of Action 579
Uses 579
Pharmacokinetics 579
Indications and Dosages 579
► Rheumatoid Arthritis, Osteoarthritis 579
PO 579
Adults, Elderly. 579
► Dysmenorrhea, Pain 580
PO 580
Adults. 580
► Usual Ophthalmic Dosage 580
Adults, Elderly, Children. 580
Side Effects/Adverse Reactions 580
Occasional 580
Rare 580
Precautions and Contraindications 580
Caution: 580
Drug Interactions of Concern to Dentistry 580
Serious Reactions 580
Dental Considerations 580
General: 580
Consultations: 580
Teach Patient/Family to: 581
flutamide 581
Category and Schedule 581
Drug Class: 581
Mechanism of Action 581
Uses 581
Pharmacokinetics 581
Indications and Dosages 581
► Prostatic Carcinoma (in Combination with Leuprolide) 581
PO 581
Adults, Elderly. 581
Side Effects/Adverse Reactions 581
Frequent 581
Occasional 581
Rare 581
Precautions and Contraindications 581
Caution: 581
Serious Reactions 582
Dental Considerations 582
General: 582
fluticasone propionate 582
Category and Schedule 582
Drug Class: 582
Mechanism of Action 582
Uses 582
Pharmacokinetics 582
Indications and Dosages 582
► Allergic Rhinitis 582
Intranasal 582
Adults, Elderly. 582
Children 4 yr and older. 582
► Relief of Inflammation and Pruritus associated with Steroid-Responsive Disorders, such as Contact Dermatitis and Eczema 582
Topical 582
Adults, Elderly, Children 3 mo and older. 582
► Maintenance Treatment for Asthma for Those Previously Treated with Bronchodilators 582
Inhalation Powder (Flovent Diskus) 582
fluticasone + vilanterol 584
Category and Schedule 584
Drug Class: 584
Mechanism of Action 584
Uses 584
Pharmacokinetics 584
Indications and Dosages 584
► Asthma 584
fluvastatin 586
Category and Schedule 586
Drug Class: 586
Mechanism of Action 586
Uses 586
Pharmacokinetics 586
Indications and Dosages 586
► Hyperlipoproteinemia 586
PO 586
Adults, Elderly. 586
Patients requiring more than a 25% decrease in LDL cholesterol. 586
Side Effects/Adverse Reactions 586
Frequent 586
Occasional 586
Precautions and Contraindications 586
Caution: 586
Drug Interactions of Concern to Dentistry 586
Serious Reactions 586
fluvoxamine maleate 587
Category and Schedule 587
Drug Class: 587
Mechanism of Action 587
Uses 587
Pharmacokinetics 587
Indications and Dosages 587
► Obsessive-Compulsive Disorder 587
PO 587
Adults. 587
Children 8–17 yr. 587
Side Effects/Adverse Reactions 587
Frequent 587
Occasional 587
Rare 587
Precautions and Contraindications 587
Caution: 587
Drug Interactions of Concern to Dentistry 587
Serious Reactions 587
Dental Considerations 587
General: 587
Consultations: 588
Teach Patient/Family: 588
folic acid/sodium folate (vitamin B9) 588
Category and Schedule 588
Drug Class: 588
Mechanism of Action 588
Uses 588
Pharmacokinetics 588
Indications and Dosages 588
► Vitamin B9 Deficiency 588
formoterol fumarate 589
Category and Schedule 589
Drug Class: 589
Mechanism of Action 589
Uses 589
Pharmacokinetics 589
Indications and Dosages 589
► Asthma, COPD 589
fosamprenavir 590
Category and Schedule 590
Drug Class: 590
Mechanism of Action 590
Uses 590
Pharmacokinetics 591
Indications and Dosages 591
► HIV Infection in Patients Who Have Not Had Previous Protease Inhibitor Therapy 591
foscarnet sodium 592
Category and Schedule 592
Drug Class: 592
Mechanism of Action 592
Uses 592
Pharmacokinetics 592
Indications and Dosages 592
► CMV Retinitis 592
fosfomycin tromethamine 593
Category and Schedule 593
Drug Class: 593
Mechanism of Action 593
Uses 593
Pharmacokinetics 593
Indications and Dosages 594
► Uncomplicated UTIs 594
PO 594
Females. 594
Males. 594
Side Effects/Adverse Reactions 594
Occasional 594
Rare 594
Precautions and Contraindications 594
Caution: 594
Drug Interactions of Concern to Dentistry 594
Serious Reactions 594
Dental Considerations 594
General: 594
Teach Patient/Family: 594
fosinopril 594
Category and Schedule 594
Drug Class: 594
Mechanism of Action 594
Uses 594
Pharmacokinetics 594
Indications and Dosages 595
► Hypertension (Monotherapy) 595
fosphenytoin 596
Category and Schedule 596
Drug Class: 596
Mechanism of Action 596
Uses 596
Pharmacokinetics 596
Indications and Dosages 596
► Status Epilepticus 596
IV 596
frovatriptan 597
Category and Schedule 597
Drug Class: 597
Mechanism of Action 597
Uses 597
Pharmacokinetics 597
Indications and Dosages 598
► Acute Migraine Attack 598
PO 598
Adults, Elderly. 598
Side Effects/Adverse Reactions 598
Occasional 598
Rare 598
Precautions and Contraindications 598
Drug Interactions of Concern to Dentistry 598
Serious Reactions 598
Dental Considerations 598
General: 598
Consultations: 598
Teach Patient/Family to: 598
furosemide 598
Category and Schedule 598
Drug Class: 598
Mechanism of Action 599
Uses 599
Pharmacokinetics 599
Indications and Dosages 599
► Edema, Hypertension 599
PO 599
gabapentin 601
Category and Schedule 601
Drug Class: 601
Mechanism of Action 601
Uses 601
Pharmacokinetics 601
Indications and Dosages 601
► Adjunctive Therapy for Seizure Control 601
galantamine 602
Category and Schedule 602
Drug Class: 602
Mechanism of Action 602
Uses 602
Pharmacokinetics 603
Indications and Dosages 603
► Alzheimer’s Disease 603
PO 603
Adults, Elderly. 603
► Dosage in Renal Impairment 603
Side Effects/Adverse Reactions 603
Frequent 603
Occasional 603
Rare 603
Precautions and Contraindications 603
Caution: 603
Drug Interactions of Concern to Dentistry 603
Serious Reactions 603
Dental Considerations 603
General: 603
Consultations: 603
Teach Patient/Family to: 604
galsulfase 604
Category and Schedule 604
Drug Class: 604
Mechanism of Action 604
Uses 604
Pharmacokinetics 604
Indications and Dosages 604
► Maroteaux-Lamy Syndrome 604
IV 604
Adults. 604
Children (5 yr and older). 604
Side Effects/Adverse Reactions 604
Frequent 604
Precautions and Contraindications 604
Caution: 604
Drug Interactions of Concern to Dentistry 604
Serious Reactions 604
Dental Considerations 604
General 604
Consultations: 605
Teach Patient/Family to: 605
ganciclovir sodium 605
Category and Schedule 605
Drug Class: 605
Mechanism of Action 605
Uses 605
Pharmacokinetics 605
Indications and Dosages 605
► CMV Retinitis 605
gefitinib 607
Category and Schedule 607
Drug Class: 607
Mechanism of Action 607
Uses 607
Pharmacokinetics 607
Indications and Dosages 607
► Non–Small-Cell Lung Cancer 607
PO 607
Adults, Elderly. 607
Side Effects/Adverse Reactions 607
Frequent 607
Occasional 607
Rare 607
Precautions and Contraindications 607
Drug Interactions of Concern to Dentistry 607
Serious Reactions 607
Dental Considerations 607
General: 607
Consultations: 608
Teach Patient/Family to: 608
gemcitabine hydrochloride 608
Category and Schedule 608
Drug Class: 608
Mechanism of Action 608
Uses 608
Pharmacokinetics 608
Indications and Dosages 608
► Non–Small-Cell Lung Cancer (in Combination with Cisplatin) 608
gemfibrozil 610
Category and Schedule 610
Drug Class: 610
Mechanism of Action 610
Uses 610
Pharmacokinetics 610
Indications and Dosages 610
► Hyperlipidemia 610
PO 610
Adults, Elderly. 610
Side Effects/Adverse Reactions 610
Frequent 610
Occasional 610
Rare 610
Precautions and Contraindications 610
Caution: 610
Drug Interactions of Concern to Dentistry 610
Serious Reactions 610
Dental Considerations 610
General: 610
Consultations: 611
gemifloxacin mesylate 611
Category and Schedule 611
Drug Class: 611
Mechanism of Action 611
Uses 611
Pharmacokinetics 611
Indications and Dosages 611
► Acute Bacterial Exacerbation of Chronic Bronchitis 611
gentamicin sulfate 612
Category and Schedule 612
Drug Class: 612
Mechanism of Action 612
Uses 612
Pharmacokinetics 612
Indications and Dosages 613
► Acute Pelvic, Bone, Intraabdominal, Joint, Respiratory Tract, Burn Wound, Postoperative and Skin or Skin-Structure Infections; Complicated UTIs; Septicemia; Meningitis 613
gentamicin sulfate; prednisolone acetate 614
Category and Schedule 614
Drug Class: 614
Mechanism of Action 614
Uses 614
Pharmacokinetics 614
Indications and Dosages 614
► Treatment of Steroid Responsive Inflammatory Conditions, Superficial Ocular Infections 614
Ophthalmic Ointment 614
glatiramer 615
Category and Schedule 615
Drug Class: 615
Mechanism of Action 615
Uses 615
Pharmacokinetics 615
Indications and Dosages 615
► Multiple Sclerosis 615
Subcutaneous 615
Adults, Elderly. 615
Side Effects/Adverse Reactions 615
Expected 615
Frequent 615
Occasional 615
Rare 615
Precautions and Contraindications 615
Drug Interactions of Concern to Dentistry 615
Serious Reactions 615
Dental Considerations 615
General: 615
Dental Considerations 616
General: 616
Consultations: 616
Teach Patient/Family to: 616
glimepiride 616
Category and Schedule 616
Drug Class: 616
Mechanism of Action 616
Uses 616
Pharmacokinetics 616
Indications and Dosages 616
► Diabetes Mellitus 616
PO 616
Adults, Elderly. 616
► Dosage in Renal Impairment 617
PO 617
Adults. 617
Side Effects/Adverse Reactions 617
Frequent 617
Occasional 617
Precautions and Contraindications 617
Caution: 617
Drug Interactions of Concern to Dentistry 617
Serious Reactions 617
Dental Considerations 617
General: 617
Consultations: 617
Teach Patient/Family to: 617
glipizide 618
Category and Schedule 618
Drug Class: 618
Mechanism of Action 618
Uses 618
Pharmacokinetics 618
Indications and Dosages 618
► Diabetes Mellitus 618
PO 618
Adults. 618
Elderly. 618
Side Effects/Adverse Reactions 618
Frequent 618
Occasional 618
Precautions and Contraindications 618
Caution: 618
Drug Interactions of Concern to Dentistry 618
Serious Reactions 618
Dental Considerations 619
General: 619
Consultations: 619
Teach Patient/Family to: 619
glucagon hydrochloride 619
Category and Schedule 619
Drug Class: 619
Mechanism of Action 619
Uses 619
Pharmacokinetics 619
Indications and Dosages 620
► Hypoglycemia 620
IV, IM, Subcutaneous 620
Adults, Elderly, Children weighing more than 20 kg. 620
Children weighing 20 kg or less. 620
► Diagnostic Aid 620
IV, IM 620
Adults, Elderly. 620
Side Effects/Adverse Reactions 620
Occasional 620
Rare 620
Precautions and Contraindications 620
Caution: 620
Drug Interactions of Concern to Dentistry 620
Serious Reactions 620
Dental Considerations 620
General: 620
glyburide 620
Category and Schedule 620
Drug Class: 620
Mechanism of Action 620
Uses 620
Pharmacokinetics 620
Indications and Dosages 621
► Diabetes Mellitus 621
PO 621
Adults. 621
Elderly. 621
PO (Micronized Tablets [Glynase]) 621
Adults, Elderly. 621
► Dosage in Renal Impairment 621
Side Effects/Adverse Reactions 621
Frequent 621
Occasional 621
Precautions and Contraindications 621
Caution: 621
Drug Interactions of Concern to Dentistry 621
Serious Reactions 621
Dental Considerations 621
General: 621
Consultations: 622
Teach Patient/Family to: 622
glycerol phenylbutyrate 622
Category and Schedule 622
Drug Class: 622
Mechanism of Action 622
Uses 622
Pharmacokinetics 622
Indications and Dosages 622
► Urea Cycle Disorders 622
PO 622
Adults. 622
Side Effects/Adverse Reactions 622
Frequent 622
Occasional 622
Precautions and Contraindications 623
Drug Interactions of Concern to Dentistry 623
Serious Reactions 623
Dental Considerations 623
General: 623
Consultations: 623
Teach Patient/Family to: 623
glycopyrrolate 623
Category and Schedule 623
Drug Class: 623
Mechanism of Action 623
Uses 623
Pharmacokinetics 623
Indications and Dosages 623
► Preoperative Inhibition of Salivation and Excessive Respiratory Tract Secretions 623
IM 623
Adults, Elderly. 623
Children 2 yr and older. 623
Children younger than 2 yr. 623
► To Block Effects of Anticholinesterase Agents 624
IV 624
goserelin acetate 625
Category and Schedule 625
Drug Class: 625
Mechanism of Action 625
Uses 625
Pharmacokinetics 625
Indications and Dosages 625
► Prostatic Carcinoma 625
granisetron 626
Category and Schedule 626
Drug Class: 626
Mechanism of Action 626
Uses 627
Pharmacokinetics 627
Indications and Dosages 627
► Prevention of Chemotherapy-Induced Nausea and Vomiting 627
griseofulvin 628
Category and Schedule 628
Drug Class: 628
Mechanism of Action 628
Uses 628
Pharmacokinetics 628
Indications and Dosages 628
► Tinea Capitis, Tinea Corporis, Tinea Cruris, Tinea Pedis, Tinea Unguium 628
PO (Microsize Tablets, Oral Suspension) 628
guaifenesin 629
Category and Schedule 629
Drug Class: 629
Mechanism of Action 629
Uses 629
Pharmacokinetics 629
guanabenz 630
Category and Schedule 630
Drug Class: 630
Mechanism of Action 630
Uses 630
Pharmacokinetics 630
Indications and Dosages 630
► Expectorant 630
► Hypertension 630
PO 630
Adults. 630
Elderly. 630
Side Effects/Adverse Reactions 630
Rare 630
Precautions and Contraindications 630
Serious Reactions 630
Dental Considerations 630
General: 630
Frequent 630
Occasional 631
Rare 631
Precautions and Contraindications 631
Caution: 631
Drug Interactions of Concern to Dentistry 631
Serious Reactions 631
Dental Considerations 631
General: 631
Consultations: 631
Teach Patient/Family: 631
guanadrel sulfate 631
Category and Schedule 631
Drug Class: 631
Mechanism of Action 631
Uses 631
Pharmacokinetics 632
Indications and Dosages 632
► Hypertension 632
PO 632
Adults. 632
Elderly. 632
Side Effects/Adverse Reactions 632
Frequent 632
Occasional 632
Rare 632
Precautions and Contraindications 632
Caution: 632
Drug Interactions of Concern to Dentistry 632
Serious Reactions 632
Dental Considerations 632
General: 632
Consultations: 632
Teach Patient/Family: 632
guanethidine monosulfate 633
Category and Schedule 633
Drug Class: 633
Mechanism of Action 633
Uses 633
Pharmacokinetics 633
Indications and Dosages 633
► Hypertension 633
PO 633
Adults. 633
Side Effects/Adverse Reactions 633
Frequent 633
Occasional 633
Rare 633
Precautions and Contraindications 633
Caution: 633
Drug Interactions of Concern to Dentistry 633
Serious Reactions 633
Dental Considerations 633
General: 633
Consultations: 634
Teach Patient/Family to: 634
guanfacine 634
Category and Schedule 634
Drug Class: 634
Mechanism of Action 634
Uses 634
Pharmacokinetics 634
Indications and Dosages 634
► Hypertension 634
PO 634
Adults, Elderly. 634
Side Effects/Adverse Reactions 635
Frequent 635
Occasional 635
Precautions and Contraindications 635
Drug Interactions of Concern to Dentistry 635
Serious Reactions 635
Dental Considerations 635
General: 635
Consultations: 635
Teach Patient/Family to: 635
halcinonide 636
Category and Schedule 636
Drug Class: 636
Mechanism of Action 636
Uses 636
Pharmacokinetics 636
Indications and Dosages 636
► Dermatoses 636
Topical 636
Adults, Elderly. 636
Side Effects/Adverse Reactions 636
Occasional 636
Rare 636
Precautions and Contraindications 636
Serious Reactions 636
Dental Considerations 636
General: 636
Teach Patient/Family to: 636
Mechanism of Action 637
Uses 637
Pharmacokinetics 637
Indications and Dosages 637
► Treatment of Psychotic Disorders 637
haloperidol 636
histrelin 639
Category and Schedule 639
Drug Class: 639
Mechanism of Action 639
Uses 639
Pharmacokinetics 639
Indications and Dosages 639
Adult. 639
Pediatric. 639
Side Effects/Adverse Reactions 639
Frequent 639
Occasional 639
Precautions and Contraindications 639
Drug Interactions of Concern to Dentistry 639
Serious Reactions 639
Dental Considerations 640
Consultations: 640
Teach Patient/Family to: 640
homatropine hydrobromide 640
Category and Schedule 640
Drug Class: 640
Mechanism of Action 640
Uses 640
Pharmacokinetics 640
Indications and Dosages 640
► Mydriasis and Cycloplegia for Refraction 640
hydralazine hydrochloride 641
Category and Schedule 641
Drug Class: 641
Mechanism of Action 641
Uses 641
Pharmacokinetics 641
Indications and Dosages 641
► Moderate to Severe Hypertension 641
PO 641
Adults. 641
hydrochlorothiazide 642
Category and Schedule 642
Drug Class: 642
Mechanism of Action 643
Uses 643
Pharmacokinetics 643
Indications and Dosages 643
► Edema, Hypertension 643
hydrocodone bitartrate 644
Category and Schedule 644
Drug Class: 644
Mechanism of Action 644
Uses 644
Pharmacokinetics 644
Indications and Dosages 645
► Analgesia 645
hydrocodone 646
Category and Schedule 646
Drug Class: 646
Mechanism of Action 646
Uses 646
Pharmacokinetics 646
Indications and Dosages 646
Analgesia 646
► Hydrocodone and Acetaminophen 646
hydrocortisone 648
Category and Schedule 648
Drug Class: 648
Mechanism of Action 648
Uses 648
Pharmacokinetics 648
Indications and Dosages 648
► Acute Adrenal Insufficiency 648
hydroflumethiazide 650
Category and Schedule 650
Drug Class: 650
Mechanism of Action 650
Uses 650
Pharmacokinetics 650
Indications and Dosages 650
► Edema 650
PO 650
Adults, Elderly. 650
► Hypertension 650
Adults, Elderly, Children. 650
Side Effects/Adverse Reactions 650
Expected 650
Frequent 650
Occasional 650
Precautions and Contraindications 650
Drug Interactions of Concern to Dentistry 650
Serious Reactions 650
Dental Considerations 651
General: 651
Consultations: 651
Teach Patient/Family to: 651
hydromorphone hydrochloride 651
Category and Schedule 651
Drug Class: 651
Mechanism of Action 652
Uses 652
Pharmacokinetics 652
Indications and Dosages 652
► Analgesia 652
hydroxychloroquine sulfate 653
Category and Schedule 653
Drug Class: 653
Mechanism of Action 653
Uses 653
Pharmacokinetics 653
Indications and Dosages 654
► Treatment of Acute Attack of Malaria (Dosage in mg Base) 654
hydroxyurea 655
Category and Schedule 655
Drug Class: 655
Mechanism of Action 655
Uses 655
Pharmacokinetics 655
Indications and Dosages 655
► Melanoma; Recurrent, Metastatic, or Inoperable Ovarian Carcinoma 655
hydroxyzine 656
Category and Schedule 656
Drug Class: 656
Mechanism of Action 656
Uses 656
Pharmacokinetics 657
Indications and Dosages 657
► Anxiety 657
hyoscyamine 658
Category and Schedule 658
Drug Class: 658
Mechanism of Action 658
Uses 658
Pharmacokinetics 658
Indications and Dosages 658
► GI Tract Disorders 658
ibandronate sodium 660
Category and Schedule 660
Drug Class: 660
Mechanism of Action 660
Uses 660
PharmacoKinetics 660
Indications and Dosages 660
► Osteoporosis 660
PO 660
Adults, Elderly. 660
Side Effects/Adverse Reactions 660
Frequent 660
Occasional 660
Rare 660
Precautions and Contraindications 660
Drug Interactions of Concern to Dentistry 660
Serious Reactions 660
Dental Considerations 660
General: 660
Consultations: 661
Teach Patient/Family to: 661
ibuprofen 661
Category and Schedule 661
Drug Class: 661
Mechanism of Action 661
Uses 661
Pharmacokinetics 661
Indications and Dosages 661
► Acute or Chronic Rheumatoid Arthritis, Osteoarthritis, Migraine Pain, Gouty Arthritis 661
ibuprofen + famotidine 663
Category and Schedule 663
Drug Class: 663
Mechanism of Action 663
Uses 663
Pharmacokinetics 663
Indications and Dosages 663
► NSAID-Associated Ulcer Prophylaxis During Treatment for Osteoarthritis/Rheumatoid Arthritis 663
PO 663
Adults. 663
Side Effects/Adverse Reactions 663
Frequent 663
Occasional 663
Precautions and Contraindications 663
Drug Interactions of Concern to Dentistry 664
Serious Reactions 664
Dental Considerations 664
General: 664
Consultations: 664
Teach Patient/Family to: 664
ibutilide fumarate 664
Category and Schedule 664
Drug Class: 664
Mechanism of Action 664
Uses 665
Pharmacokinetics 665
Indications and Dosages 665
► Rapid Conversion of Atrial Fibrillation or Flutter of Recent Onset to Normal Sinus Rhythm 665
IV Infusion 665
Adults, Elderly weighing 60 kg and more. 665
Adults, Elderly weighing less than 60 kg. 665
Side Effects/Adverse Reactions 665
Occasional 665
Rare 665
Precautions and Contraindications 665
Drug Interactions of Concern to Dentistry 665
Serious Reactions 665
Dental Considerations 665
General: 665
Consultations: 665
Teach Patient/Family to: 665
idarubicin hydrochloride 666
Category and Schedule 666
Drug Class: 666
Mechanism of Action 666
Uses 666
Pharmacokinetics 666
Indications and Dosages 666
► AML 666
IV 666
Adults. 666
Children (solid tumor). 666
Children (leukemia). 666
► Dosage in Hepatic or Renal Impairment 666
Side Effects/Adverse Reactions 666
Frequent 666
Occasional 666
Rare 666
Precautions and Contraindications 666
Drug Interactions of Concern to Dentistry 666
Serious Reactions 666
Dental Considerations 667
General: 667
Consultations: 667
Teach Patient/Family to: 667
idelalisib 667
Category and Schedule 667
Drug Class: 667
Mechanism of Action 667
Uses 667
Pharmacokinetics 668
Indications and Dosages 668
► Chronic Lymphocytic Leukemia, Relapsed 668
idursulfase 669
Category and Schedule 669
Drug Class: 669
Mechanism of Action 669
Uses 669
Pharmacokinetics 669
Indications and Dosages 669
► Hunter Syndrome 669
IV 669
Adults. 669
Children (5 yr and older). 669
Side Effects/Adverse Reactions 669
Frequent 669
Rare 669
Precautions and Contraindications 669
Caution: 669
Drug Interactions of Concern to Dentistry 669
Serious Reactions 669
Dental Considerations 669
General: 669
Consultations: 669
Teach Patient/Family to: 669
ifosfamide 670
Category and Schedule 670
Drug Class: 670
Mechanism of Action 670
Uses 670
Pharmacokinetics 670
Indications and Dosages 670
► Germ Cell Testicular Carcinoma 670
IV 670
Adults. 670
Children. 670
Side Effects/Adverse Reactions 670
Frequent 670
Occasional 670
Rare 670
Precautions and Contraindications 670
Drug Interactions of Concern to Dentistry 670
Serious Reactions 670
Dental Considerations 670
General: 670
Consultations: 671
Teach Patient/Family to: 671
iloperidone 671
Category and Schedule 671
Drug Class: 671
Mechanism of Action 671
Uses 671
Pharmacokinetics 671
Indications and Dosages 672
► Schizophrenia 672
PO 672
Adults. 672
Side Effects/Adverse Reactions 672
Frequent 672
Occasional 672
Rare 672
Precautions and Contraindications 672
Caution: 672
Drug Interactions of Concern to Dentistry 672
Serious Reactions 672
Dental Considerations 672
General: 672
Consultations: 673
Teach Patient/Family to: 673
iloprost 673
Category and Schedule 673
Drug Class: 673
Mechanism of Action 673
Uses 673
Pharmacokinetics 673
Indications and Dosages 673
► Pulmonary Hypertension in Patients with NYHA Class III or IV Symptoms 673
Oral Inhalation 673
Adults, Elderly. 673
Side Effects/Adverse Reactions 674
Frequent 674
Occasional 674
Rare 674
Precautions and Contraindications 674
Caution: 674
Drug Interactions of Concern to Dentistry 674
Serious Reactions 674
Dental Considerations 674
General: 674
Consultations: 674
Teach Patient/Family to: 674
imatinib mesylate 674
Category and Schedule 674
Drug Class: 674
Mechanism of Action 674
Uses 675
Pharmacokinetics 675
Indications and Dosages 675
► CML 675
PO 675
Adults, Elderly. 675
Children. 675
Side Effects/Adverse Reactions 675
Frequent 675
Occasional 675
Rare 675
Precautions and Contraindications 675
Caution: 675
Drug Interactions of Concern to Dentistry 675
Serious Reactions 675
Dental Considerations 676
General: 676
Consultations: 676
Teach Patient/Family to: 676
imipramine 676
Category and Schedule 676
Drug Class: 676
Mechanism of Action 676
Uses 676
Pharmacokinetics 676
Indications and Dosages 676
► Depression 676
PO 676
Adults. 676
Elderly. 677
Children. 677
► Enuresis 677
PO 677
Children older than 6 yr. 677
Side Effects/Adverse Reactions 677
Frequent 677
Occasional 677
Rare 677
Precautions and Contraindications 677
Caution: 677
Drug Interactions of Concern to Dentistry 677
Serious Reactions 677
Dental Considerations 677
General: 677
Consultations: 678
Teach Patient/Family to: 678
imiquimod 678
Category and Schedule 678
Drug Class: 678
Mechanism of Action 678
Uses 678
Pharmacokinetics 678
Indications and Dosages 678
► Warts/Condyloma Acuminata 678
Topical 678
Adults, Elderly, Children 12 yr and older. 678
Side Effects/Adverse Reactions 678
Frequent 678
Occasional 678
indacaterol 679
Category and Schedule 679
Drug Class: 679
Mechanism of Action 679
Uses 679
Pharmacokinetics 679
Indications and Dosages 679
► COPD, Maintenance 679
Oral inhalation 679
Adults. 679
Side Effects/Adverse Reactions 679
Frequent 679
Occasional 679
Precautions and Contraindications 679
Caution: 679
Drug Interactions of Concern to Dentistry 679
Serious Reactions 679
Dental Considerations 679
General: 679
Consultations: 679
Teach Patient/Family to: 679
Drug Interactions of Concern to Dentistry 680
Serious Reactions 680
Dental Considerations 680
General: 680
Consultations: 680
Teach Patient/Family to: 680
indapamide 680
Category and Schedule 680
Drug Class: 680
Mechanism of Action 680
Uses 680
Pharmacokinetics 680
Indications and Dosages 681
► Edema 681
indinavir 682
Category and Schedule 682
Drug Class: 682
Mechanism of Action 682
Uses 682
PharmacoKinetics 682
Indications and Dosages 682
► HIV Infection (in Combination with Other Antiretrovirals) 682
indomethacin 683
Category and Schedule 683
Drug Class: 683
Mechanism of Action 683
Uses 683
PharmacoKinetics 683
Indications and Dosages 684
► Moderate-to-Severe Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis 684
infliximab 685
Category and Schedule 685
Drug Class: 685
Mechanism of Action 685
Uses 685
PharmacoKinetics 686
Indications and Dosages 686
► Moderate-to-Severe Crohn’s Disease 686
ingenol mebutate 687
Category and Schedule 687
Drug Class: 687
Mechanism of Action 687
Uses 687
Pharmacokinetics 687
Indications and Dosages 687
► Actinic Keratoses 687
Topical 687
Adults. 687
Side Effects/Adverse Reactions 687
Frequent 687
Occasional 687
Precautions and Contraindications 687
Drug Interactions of Concern to Dentistry 687
Serious Reactions 687
Dental Considerations 687
General: 687
Teach Patient/Family to: 687
insulin 688
Category and Schedule 688
Drug Class: 688
Mechanism of Action 688
Uses 688
PharmacoKinetics 688
Indications and Dosages 688
► Treatment of Insulin-Dependent Type 1 Diabetes Mellitus and Non–Insulin-Dependent Type 2 Diabetes Mellitus When Diet or Weight Control Has Failed to Maintain Satisfactory Blood Glucose Levels or in Event of Fever, Infection, Pregnancy, Surgery, or Trauma, or Severe Endocrine, Hepatic or Renal Dysfunction; Emergency Treatment of Ketoacidosis (Regular Insulin); to Promote Passage of Glucose Across Cell Membrane in Hyperalimentation (Regular Insulin): to Facilitate Intracellular Shift of Potassium in Hyperkalemia (Regular Insulin) 688
Subcutaneous 688
Adults, Elderly, Children. 688
Adolescents (during growth spurt). 688
Side Effects/Adverse Reactions 688
Occasional 688
Infrequent 689
Rare 689
Precautions and Contraindications 689
Drug Interactions of Concern to Dentistry 689
Serious Reactions 689
Dental Considerations 689
General: 689
Consultations: 689
Teach Patient/Family to: 689
insulin glargine 689
Category and Schedule 689
Drug Class: 689
Mechanism of Action 690
Uses 690
PharmacoKinetics 690
Indications and Dosages 690
► Treatment of Insulin-Dependent Type 1 Diabetes Mellitus, Non–Insulin-Dependent Type 2 Diabetes Mellitus When Diet or Weight Control Therapy Has Failed to Maintain Satisfactory Blood Glucose Levels or in Event of Fever, Infection, Pregnancy, Severe Endocrine, Liver or Renal Dysfunction, Surgery, or Trauma, Regular Insulin Used in Emergency Treatment of Ketoacidosis, to Promote Passage of Glucose Across Cell Membrane in Hyperalimentation, to Facilitate Intracellular Shift of Potassium in Hyperkalemia 690
Subcutaneous 690
Adults, Elderly, Children. 690
Side Effects/Adverse Reactions 690
Frequent 690
Occasional 690
Infrequent 690
Rare 690
Precautions and Contraindications 690
Drug Interactions of Concern to Dentistry 690
Serious Reactions 691
Dental Considerations 691
General: 691
Consultations: 691
Teach Patient/Family to: 691
insulin glulisine 691
Category and Schedule 691
Drug Class: 691
Mechanism of Action 691
Uses 691
PharmacoKinetics 691
Indications and Dosages 692
► Diabetes Mellitus (Type 1 and Type 2) 692
Subcutaneous, Infusion Pump 692
Adults, Elderly, Children. 692
Side Effects/Adverse Reactions 692
Occasional 692
Infrequent 692
Rare 692
Precautions and Contraindications 692
Drug Interactions of Concern to Dentistry 692
Serious Reactions 692
Dental Considerations 692
General: 692
Consultations: 692
Teach Patient/Family to: 692
interferon alfa-2a 693
Category and Schedule 693
Drug Class: 693
Mechanism of Action 693
Uses 693
PharmacoKinetics 693
Indications and Dosages 693
► Hairy Cell Leukemia 693
interferon alfa-2a/2b 694
Category and Schedule 694
Drug Class: 694
Mechanism of Action 695
Uses 695
PharmacoKinetics 695
interferon alfa-2b 697
Category and Schedule 697
Drug Class: 697
Mechanism of Action 697
Uses 697
PharmacoKinetics 697
Indications and Dosages 697
► Hairy-Cell Leukemia 697
IM, Subcutaneous 697
Adults. 697
► Condyloma Acuminatum 698
Intralesional 698
interferon alfa-n3 699
Category and Schedule 699
Drug Class: 699
Mechanism of Action 699
Uses 699
PharmacoKinetics 699
Indications and Dosages 699
► Condyloma Acuminatum 699
Intralesional 699
Adults, Children 18 yr and older. 699
Side Effects/Adverse Reactions 699
Frequent 699
Occasional 700
Rare 700
Precautions and Contraindications 700
Caution: 700
Drug Interactions of Concern to Dentistry 700
Serious Reactions 700
Dental Considerations 700
General: 700
Consultations: 700
Teach Patient/Family to: 700
interferon gamma-1b 700
Category and Schedule 700
Drug Class: 700
Mechanism of Action 700
Uses 700
PharmacoKinetics 700
Indications and Dosages 701
► Chronic Granulomatous Disease; Severe, Malignant Osteoporosis 701
Subcutaneous 701
Adults, Children older than 1 yr. 701
Side Effects/Adverse Reactions 701
Frequent 701
Occasional 701
Rare 701
Precautions and Contraindications 701
Caution: 701
Drug Interactions of Concern to Dentistry 701
Serious Reactions 701
Dental Considerations 701
General: 701
Consultations: 701
Teach Patient/Family to: 701
ipratropium bromide 702
Category and Schedule 702
Drug Class: 702
Mechanism of Action 702
Uses 702
PharmacoKinetics 702
Indications and Dosages 702
► Bronchospasm, Acute Treatment 702
irbesartan 703
Category and Schedule 703
Drug Class: 703
Mechanism of Action 703
Uses 703
PharmacoKinetics 703
Indications and Dosages 704
► Hypertension Alone or in Combination with Other Antihypertensives 704
isavuconazonium sulfate 704
Category and Schedule 704
Drug Class: 704
Mechanism of Action 705
Uses 705
Pharmacokinetics 705
Indications and Dosages 705
► Aspergillosis, Invasive 705
isocarboxazid 706
Category and Schedule 706
Drug Class: 706
Mechanism of Action 706
Uses 706
PharmacoKinetics 706
Indications and Dosages 706
► Depression Refractory to Other Antidepressants or Electroconvulsive Therapy 706
PO 706
Adults, Elderly. 706
Side Effects/Adverse Reactions 706
Frequent 706
Occasional 707
Rare 707
Precautions and Contraindications 707
Caution: 707
Drug Interactions of Concern to Dentistry 707
Serious Reactions 707
Dental Considerations 707
General: 707
Consultations: 707
Teach Patient/Family: 707
isoetharine hydrochloride 708
Category and Schedule 708
Drug Class: 708
Mechanism of Action 708
Uses 708
PharmacoKinetics 708
Indications and Dosages 708
► Bronchospasm 708
Hand-Bulb Nebulizer 708
isoniazid 709
Category and Schedule 709
Drug Class: 709
Mechanism of Action 709
Uses 709
PharmacoKinetics 709
Indications and Dosages 709
► TB (in Combination with One or More Antituberculars) 709
isosorbide 710
Category and Schedule 710
Drug Class: 710
Mechanism of Action 710
Uses 710
PharmacoKinetics 710
Indications and Dosages 711
► Acute Angina, Prophylactic Management in Situations Likely to Provoke Attack 711
isosorbide dinitrate/isosorbide mononitrate 712
Category and Schedule 712
Drug Class: 712
Mechanism of Action 712
Uses 712
PharmacoKinetics 712
Indications and Dosages 713
► Angina 713
PO (Isosorbide Dinitrate) 713
isoxsuprine hydrochloride 714
Category and Schedule 714
Drug Class: 714
Mechanism of Action 714
Uses 714
PharmacoKinetics 714
Indications and Dosages 714
► Raynaud’s Syndrome 714
IV Infusion 714
Adults, Elderly. 714
Side Effects/Adverse Reactions 714
Rare 714
Precautions and Contraindications 714
Caution: 714
Drug Interactions of Concern to Dentistry 714
Serious Reactions 714
Dental Considerations 714
General: 714
Consultations: 715
isradipine 715
Category and Schedule 715
Drug Class: 715
Mechanism of Action 715
Uses 715
PharmacoKinetics 715
Indications and Dosages 715
► Hypertension 715
PO 715
Adults, Elderly. 715
Side Effects/Adverse Reactions 715
Frequent 715
Occasional 715
Rare 715
Precautions and Contraindications 715
Caution: 715
Drug Interactions of Concern to Dentistry 716
Serious Reactions 716
Dental Considerations 716
General: 716
Consultations: 716
Teach Patient/Family to: 716
itraconazole 716
Category and Schedule 716
Drug Class: 716
Mechanism of Action 716
Uses 717
PharmacoKinetics 717
Indications and Dosages 717
► Blastomycosis, Histoplasmosis 717
ivabradine 718
Category and Schedule 718
Drug Class: 718
Mechanism of Action 718
Uses 718
Pharmacokinetics 718
Indications and Dosages 718
► Heart Failure 718
PO 718
Adults. 718
Side Effects/Adverse Reactions 719
Frequent 719
Occasional 719
Precautions and Contraindications 719
Drug Interactions of Concern to Dentistry 719
Serious Reactions 719
Dental Considerations 719
General: 719
Consultations: 719
Teach Patient/Family to: 719
ivacaftor 720
Category and Schedule 720
Drug Class: 720
Mechanism of Action 720
Uses 720
Pharmacokinetics 720
Indications and Dosages 720
► Cystic Fibrosis 720
Oral 720
Adults. 720
Children older than 6 yr. 720
► Dosage in Hepatic Impairment 720
Side Effects/Adverse Reactions 720
Frequent 720
Occasional 720
Precautions and Contraindications 720
Drug Interactions of Concern to Dentistry 720
Serious Reactions 720
Dental Considerations 720
General: 720
Consultations: 721
ivermectin 721
Category and Schedule 721
Drug Class: 721
Mechanism of Action 721
Uses 721
Pharmacokinetics 721
Indications and Dosages 721
► Rosacea 721
Adults. 721
Side Effects/Adverse Reactions 721
Frequent 721
Occasional 721
Precautions and Contraindications 721
Drug Interactions of Concern to Dentistry 721
Serious Reactions 721
Dental Considerations 721
General: 721
Teach Patient/Family to: 721
Mechanism of Action 722
Uses 722
PharmacoKinetics 722
Indications and Dosages 722
Adult. 722
Pediatric. 722
Dose Adjustment 722
Side Effects/Adverse Reactions 722
Frequent 722
Occasional 722
Precautions and Contraindications 722
Drug Interactions of Concern to Dentistry 723
Serious Reactions 723
Dental Considerations 723
General: 723
Consultations: 723
Teach Patient/Family to: 723
ixabepilone 721
kanamycin sulfate 724
Category and Schedule 724
Drug Class: 724
Mechanism of Action 724
Uses 724
Indications and Dosages 724
Wound and Surgical Site Irrigation 724
Adults, Elderly. 724
Side Effects/Adverse Reactions 724
Occasional 724
Rare 724
Precautions and Contraindications 724
Drug Interactions of Concern to Dentistry 724
Serious Reactions 724
Dental Considerations 724
General: 724
Consultations: 724
Teach Patient/Family to: 724
Mechanism of Action 725
Uses 725
Pharmacokinetics 725
Indications and Dosages 725
► Sole Anesthetic for Short Diagnostic and Surgical Procedures That Do Not Require Skeletal Muscle Relaxation, Induction of Anesthesia Before Administering Other General Anesthetics, Supplement to Low-Potency Agents 725
IV 725
ketamine 724
ketoconazole 726
Category and Schedule 726
Drug Class: 726
Mechanism of Action 726
Uses 726
Pharmacokinetics 726
Indications and Dosages 726
► Histoplasmosis, Blastomycosis, Systemic Candidiasis, Chronic Mucocutaneous Candidiasis, Coccidioidomycosis, Paracoccidioidomycosis, Chromomycosis, Seborrheic Dermatitis, Tinea Corporis, Tinea Capitis, Tinea Manus, Tinea Cruris, Tinea Pedis, Tinea Unguium (Onychomycosis), Oral Thrush, Candiduria 726
PO 726
ketoprofen 727
Category and Schedule 727
Drug Class: 727
Mechanism of Action 728
Uses 728
Pharmacokinetics 728
Indications and Dosages 728
► Acute or Chronic Rheumatoid Arthritis and Osteoarthritis 728
ketorolac tromethamine 729
Category and Schedule 729
Drug Class: 729
Mechanism of Action 729
Uses 729
Pharmacokinetics 729
Indications and Dosages 730
► Short-Term Relief of Mild-to-Moderate Pain (Multiple Doses) 730
PO 730
labetalol hydrochloride 732
Category and Schedule 732
Drug Class: 732
Mechanism of Action 732
Uses 732
Pharmacokinetics 732
Indications and Dosages 732
► Hypertension 732
PO 732
Side Effects/Adverse Reactions 732
Frequent 732
Occasional 732
Rare 732
Precautions and Contraindications 732
Caution: 733
Drug Interactions of Concern to Dentistry 733
Serious Reactions 733
Dental Considerations 733
General: 733
Consultations: 733
Teach Patient/Family to: 733
lacosamide 733
Category and Schedule 733
Drug Class: 733
Mechanism of Action 734
Uses 734
Pharmacokinetics 734
Indications and Dosages 734
► Partial-Onset Seizures 734
Adult. 734
Side Effects/AdversE Reactions 734
Frequent 734
Occasional 734
Precautions and Contraindications 734
Drug Interactions of Concern to Dentistry 734
Serious Reactions 734
Dental Considerations 734
General: 734
Consultations: 734
Teach Patient/Family: 734
lamivudine 735
Category and Schedule 735
Drug Class: 735
Mechanism of Action 735
Uses 735
Pharmacokinetics 735
Indications and Dosages 735
► HIV Infection (in Combination with Other Antiretrovirals) 735
Side Effects/Adverse Reactions 735
Frequent 735
Occasional 735
Precautions and Contraindications 735
Caution: 736
Drug Interactions of Concern to Dentistry 736
Serious Reactions 736
Dental Considerations 736
General: 736
Consultations: 736
Teach Patient/Family to: 736
lamotrigine 736
Category and Schedule 736
Drug Class: 736
Mechanism of Action 736
Uses 736
Pharmacokinetics 736
Indications and Dosages 736
► Seizure Control in Patients Receiving Enzyme-Inducing Antiepileptic Drug (EIAEDS), But Not Valproic Acid 736
PO 736
Adults, Elderly, Children older than 12 yr. 736
Side Effects/Adverse Reactions 737
Frequent 737
Occasional 737
Rare 737
Precautions and Contraindications 737
Caution: 737
Drug Interactions of Concern to Dentistry 738
Serious Reactions 738
Dental Considerations 738
General: 738
Consultations: 738
Teach Patient/Family to: 738
lanreotide 738
Category and Schedule 738
Drug Class: 738
Mechanism of Action 738
Uses 739
Pharmacokinetics 739
Indications and Dosages 739
SC Injection 739
Adult. 739
Dose Adjustments 739
Side Effects/Adverse Reactions 739
Frequent 739
Precautions and Contraindications 739
Drug Interactions of Concern to Dentistry 739
Serious Reactions 739
Dental Considerations 739
General: 739
Consultations: 739
Teach Patient/Family to: 740
lansoprazole 740
Category and Schedule 740
Drug Class: 740
Mechanism of Action 740
Uses 740
Pharmacokinetics 740
Indications and Dosages 740
► Duodenal Ulcer 740
Side Effects/Adverse Reactions 741
Occasional 741
Rare 741
Precautions and Contraindications 741
Caution: 741
Drug Interactions of Concern to Dentistry 741
Serious Reactions 741
Dental Considerations 741
General: 741
Teach Patient/Family to: 741
lanthanum carbonate 741
Category and Schedule 741
Drug Class: 741
Mechanism of Action 741
Uses 742
Pharmacokinetics 742
Indications and Dosages 742
► Reduce Serum Phosphate in End-Stage Renal Disease 742
PO 742
Adults, Elderly. 742
Side Effects/Adverse Reactions 742
Frequent 742
Precautions and Contraindications 742
Drug Interactions of Concern to Dentistry 742
Serious Reactions 742
Dental Considerations 742
General: 742
Consultations: 742
Teach Patient/Family to: 742
lapatinib 743
Category and Schedule 743
Drug Class: 743
Mechanism of Action 743
Uses 743
Pharmacokinetics 743
Indications and Dosages 743
► Breast Cancer 743
PO 743
Adults. 743
Side Effects/Adverse Reactions 743
Frequent 743
Occasional 743
Precautions and Contraindications 743
Drug Interactions of Concern to Dentistry 744
Serious Reactions 744
Dental Considerations 744
General: 744
Consultations: 744
Teach Patient/Family to: 744
latanoprost 744
Category and Schedule 744
Drug Class: 744
Mechanism of Action 744
Uses 744
Pharmacokinetics 745
Indications and Dosages 745
► Glaucoma, Ocular Hypertension 745
Ophthalmic 745
Adults, Elderly. 745
Side Effects/Adverse Reactions 745
Frequent 745
Occasional 745
Rare 745
Precautions and Contraindications 745
Caution: 745
Drug Interactions of Concern to Dentistry 745
Serious Reactions 745
Dental Considerations 745
General: 745
Consultations: 745
ledipasvir + sofosbuvir 746
Category and Schedule 746
Drug Class: 746
Mechanism of Action 746
Uses 746
Pharmacokinetics 746
Indications and Dosages 746
► Chronic Hepatitis C (CHC) Infection in Monoinfected (HCV) or Coinfected (HCV/HIV-1) Genotype 1 Patients 746
leflunomide 747
Category and Schedule 747
Drug Class: 747
Mechanism of Action 747
Uses 747
Pharmacokinetics 747
Indications and Dosages 748
► Rheumatoid Arthritis 748
PO 748
Adults, Elderly. 748
Side Effects/Adverse Reactions 748
Frequent 748
Precautions and Contraindications 748
Caution: 748
Drug Interactions of Concern to Dentistry 748
Serious Reactions 748
Dental Considerations 748
General: 748
Consultations: 748
Teach Patient/Family to: 748
letrozole 748
Category and Schedule 748
Drug Class: 748
Mechanism of Action 748
Uses 748
Pharmacokinetics 749
Indications and Dosages 749
► Breast Cancer 749
PO 749
Adults, Elderly. 749
Side Effects/Adverse Reactions 749
Frequent 749
Occasional 749
Rare 749
Precautions and Contraindications 749
Caution: 749
Drug Interactions of Concern to Dentistry 749
Serious Reactions 749
Dental Considerations 749
General: 749
Consultations: 749
Teach Patient/Family to: 749
leucovorin calcium (folinic acid, citrovorum factor) 749
Category and Schedule 749
Drug Class: 749
Mechanism of Action 750
Uses 750
Pharmacokinetics 750
Indications and Dosages 750
► Conventional Rescue Dosage in Methotrexate Rescue 750
PO, IV, IM 750
Side Effects/Adverse Reactions 750
Frequent 750
Occasional 750
Precautions and Contraindications 750
Drug Interactions of Concern to Dentistry 750
Serious Reactions 750
Dental Considerations 751
General: 751
Consultations: 751
Teach Patient/Family to: 751
leuprolide acetate 751
Category and Schedule 751
Drug Class: 751
Mechanism of Action 751
Uses 751
Pharmacokinetics 751
Indications and Dosages 751
► Advanced Prostatic Carcinoma 751
Side Effects/Adverse Reactions 752
Frequent 752
Occasional 752
Rare 752
Precautions and Contraindications 752
Drug Interactions of Concern to Dentistry 752
Serious Reactions 752
Dental Considerations 752
General: 752
Consultations: 752
Teach Patient/Family to: 753
levalbuterol 753
Category and Schedule 753
Drug Class: 753
Mechanism of Action 753
Uses 753
Pharmacokinetics 753
Indications and Dosages 753
► Treatment and Prevention of Bronchospasm 753
Nebulization 753
Adults, Elderly, Children 12 yr and older. 753
Children 3–11 yr. 753
Side Effects/Adverse Reactions 753
Frequent 753
Occasional 753
Rare 753
Precautions and Contraindications 753
Caution: 753
Drug Interactions of Concern to Dentistry 754
Serious Reactions 754
Dental Considerations 754
General: 754
Consultations: 754
Teach Patient/Family to: 754
levetiracetam 754
Category and Schedule 754
Drug Class: 754
Mechanism of Action 754
Uses 754
Pharmacokinetics 754
Indications and Dosages 755
► Partial-Onset Seizures 755
PO 755
Adults, Elderly. 755
Children 4–16 yr. 755
► Dosage in Renal Impairment 755
Side Effects/Adverse Reactions 755
Frequent 755
Occasional 755
Rare 755
Precautions and Contraindications 755
Caution: 755
Drug Interactions of Concern to Dentistry 755
Serious Reactions 755
Dental Considerations 755
General: 755
Consultation: 755
Teach Patient/Family to: 755
levobetaxolol hydrochloride 755
Category and Schedule 755
Drug Class: 755
Mechanism of Action 756
Uses 756
Pharmacokinetics 756
Indications and Dosages 756
► Glaucoma, Ocular Hypertension 756
Ophthalmic 756
Adults, Elderly. 756
Side Effects/Adverse Reactions 756
Frequent 756
Occasional 756
Rare 756
Precautions and Contraindications 756
Drug Interactions of Concern to Dentistry 756
Serious Reactions 756
Dental Considerations 756
General: 756
Consultations: 756
Teach Patient/Family to: 756
levobunolol hydrochloride 757
Category and Schedule 757
Drug Class: 757
Mechanism of Action 757
Uses 757
Pharmacokinetics 757
Indications and Dosages 757
► Glaucoma, Ocular Hypertension 757
Ophthalmic 757
Adults, Elderly. 757
Side Effects/ Adverse Reactions 757
Frequent 757
Occasional 757
Rare 757
Precautions and Contraindications 757
Drug Interactions of Concern to Dentistry 757
Serious Reactions 757
Dental Considerations 757
General: 757
Consultations: 757
levocabastine 758
Category and Schedule 758
Drug Class: 758
Mechanism of Action 758
Uses 758
Pharmacokinetics 758
Indications and Dosages 758
► Allergic Conjunctivitis 758
Ophthalmic 758
Adults, Elderly, Children 12 yr or older. 758
Side Effects/Adverse Reactions 758
Frequent 758
Occasional 758
Rare 758
Precautions and Contraindications 758
Caution: 758
Drug Interactions of Concern to Dentistry 758
Serious Reactions 758
Dental Considerations 758
General: 758
Teach Patient/Family to: 758
levocetirizine 759
Category and Schedule 759
Drug Class: 759
Mechanism of Action 759
Uses 759
Pharmacokinetics 759
Indications and Dosages 759
► Seasonal Rhinitis 759
Adults and Children 12 yr. 759
Children 6 to 11 yr. 759
Side Effects/Adverse Reactions 759
Frequent 759
Occasional 759
Rare 759
Precautions and Contraindications 759
Drug Interactions of Concern to Dentistry 759
Serious Reactions 759
Dental Considerations 759
General: 759
Consultations: 760
Teach Patient/Family: 760
levodopa 760
Category and Schedule 760
Drug Class: 760
Mechanism of Action 760
Uses 760
Pharmacokinetics 760
Indications and Dosages 760
► Parkinsonism 760
Adults, Elderly. 760
Side Effects/Adverse Reactions 760
Frequent 760
Occasional 760
Rare 760
Precautions and Contraindications 760
Caution: 760
Drug Interactions of Concern to Dentistry 761
Serious Reactions 761
Dental Considerations 761
General: 761
Consultations: 761
Teach Patient/Family to: 761
levofloxacin 761
Category and Schedule 761
Drug Class: 761
Mechanism of Action 761
Uses 761
Pharmacokinetics 762
Indications and Dosages 762
► Bronchitis 762
Side Effects/Adverse Reactions 762
Occasional 762
Rare 762
Precautions and Contraindications 763
Caution: 763
Drug Interactions of Concern to Dentistry 763
Serious Reactions 763
Dental Considerations 763
General: 763
Consultations: 763
Teach Patient/Family to: 763
levothyroxine 763
Category and Schedule 763
Drug Class: 763
Mechanism of Action 763
Uses 763
Pharmacokinetics 764
Indications and Dosages 764
► Hypothyroidism 764
Side Effects/Adverse Reactions 764
Occasional 764
Rare 764
Precautions and Contraindications 764
Caution: 764
Drug Interactions of Concern to Dentistry 764
Serious Reactions 764
Dental Considerations 764
General: 764
Consultations: 765
lidocaine hydrochloride 765
Category and Schedule 765
Drug Class: 765
Mechanism of Action 765
Uses 765
Pharmacokinetics 765
Indications and Dosages 765
► Rapid Control of Acute Ventricular Arrhythmias after an MI, Cardiac Catheterization, Cardiac Surgery, or Digitalis-Induced Ventricular Arrhythmias 765
IM 765
Side Effects/Adverse Reactions 766
Occasional 766
Rare 766
Precautions and Contraindications 766
Caution: 766
Drug Interactions of Concern to Dentistry 766
Patch Form 766
Injectable Form 766
Serious Reactions 766
Dental Considerations 766
► Patch Form 766
General: 766
Teach Patient/Family to: 766
lidocaine transoral delivery system 767
Category and Schedule 767
Drug Class: 767
Mechanism of Action 767
Uses 767
Pharmacokinetics 767
Indications and Dosages 767
Topical 767
Adult. 767
Side Effects/Adverse Reactions 767
Precautions and Contraindications 767
Caution: 767
Drug Interactions of Concern to Dentistry 767
Serious Reactions 767
Dental Considerations 767
General: 767
Teach Patient/Family to: 767
linaclotide 768
Category and Schedule 768
Drug Class: 768
Mechanism of Action 768
Uses 768
Pharmacokinetics 768
Indications and Dosages 768
► Chronic Idiopathic Constipation (CIC) 768
linagliptin + metformin hydrochloride 769
Category and Schedule 769
Drug Class: 769
Mechanism of Action 769
Uses 769
Pharmacokinetics 769
Indications and Dosages 769
► Type 2 Diabetes Mellitus 769
PO 769
Adults. 769
Elderly. 770
Side Effects/Adverse Reactions 770
Frequent 770
Occasional 770
Precautions and Contraindications 770
Drug Interactions of Concern to Dentistry 770
Serious Reactions 770
Dental Considerations 770
General: 770
Consultations: 770
Teach Patient/Family to: 770
lincomycin HCl 771
Category and Schedule 771
Drug Class: 771
Mechanism of Action 771
Uses 771
Pharmacokinetics 771
Indications and Dosages 771
Side Effects/Adverse Reactions 772
Frequent 772
Occasional 772
Rare 772
Precautions and Contraindications 772
Caution: 772
Drug Interactions of Concern to Dentistry 772
Serious Reactions 772
Alert 772
Dental Considerations 772
General: 772
Consultations: 772
Teach Patient/Family to: 772
linezolid 772
Category and Schedule 772
Drug Class: 772
Mechanism of Action 772
Uses 773
Pharmacokinetics 773
Indications and Dosages 773
► Vancomycin-Resistant Infections 773
Side Effects/Adverse Reactions 773
Occasional 773
Rare 773
Precautions and Contraindications 773
Caution: 773
Drug Interactions of Concern to Dentistry 773
Serious Reactions 773
Dental Considerations 774
General: 774
Consultations: 774
Teach Patient/Family to: 774
liothyronine (T3) 774
Category and Schedule 774
Drug Class: 774
Mechanism of Action 774
Uses 774
Pharmacokinetics 774
Indications and Dosages 774
► Hypothyroidism 774
PO 774
Adults, Elderly. 774
Children. 774
► Myxedema 775
Side Effects/Adverse Reactions 775
Occasional 775
Rare 775
Precautions and Contraindications 775
Caution: 775
Drug Interactions of Concern to Dentistry 775
Serious Reactions 775
Dental Considerations 775
General: 775
Consultations: 775
liraglutide 776
Category and Schedule 776
Drug Class: 776
Mechanism of Action 776
Uses 776
Pharmacokinetics 776
Indications and Dosages 776
► Treatment of Type 2 Diabetes 776
Subcutaneous injection 776
Adults. 776
Side Effects/Adverse Reactions 776
Frequent 776
Occasional 776
Precautions and Contraindications 776
Drug Interactions of Concern to Dentistry 776
Serious Reactions 776
Dental Considerations 776
General: 776
Consultations: 777
Teach Patient/Family to: 777
liotrix 777
Category and Schedule 777
Drug Class: 777
Mechanism of Action 777
Uses 777
Pharmacokinetics 777
Indications and Dosages 777
► Hypothyroidism 777
Side Effects/Adverse Reactions 778
Occasional 778
Rare 778
Precautions and Contraindications 778
Caution: 778
Drug Interactions of Concern to Dentistry 778
Serious Reactions 778
Dental Considerations 778
General: 778
Consultations: 778
Teach Patient/Family to: 778
lisdexamfetamine dimesylate 778
Category and Schedule 778
Drug Class: 778
Mechanism of Action 779
Uses 779
Pharmacokinetics 779
Indications and Dosages 779
► ADHD 779
PO 779
Adults. 779
Children (6–12 yr). 779
Side Effects/Adverse Reactions 779
Adult 779
Precautions and Contraindications 779
Drug Interactions of Concern to Dentistry 779
Serious Reactions 780
Dental Considerations 780
General: 780
Teach Patient/Family to: 780
lisinopril 780
Category and Schedule 780
Drug Class: 780
Mechanism of Action 780
Uses 780
Pharmacokinetics 781
Indications and Dosages 781
► Hypertension (Used Alone) 781
Side Effects/Adverse Reactions 781
Frequent 781
Occasional 781
Rare 781
Precautions and Contraindications 781
Caution: 781
Drug Interactions of Concern to Dentistry 781
Serious Reactions 781
Dental Considerations 782
General: 782
Consultations: 782
Teach Patient/Family to: 782
lithium carbonate/lithium citrate 782
Category and Schedule 782
Drug Class: 782
Mechanism of Action 782
Uses 783
Pharmacokinetics 783
Indications and Dosages 783
Alert 783
► Prevention or Treatment of Acute Mania, Manic Phase of Bipolar Disorder (Manic-Depressive Illness) 783
PO 783
Adults. 783
Elderly. 783
Children 12 yr and older. 783
Children younger than 12 yr. 783
Side Effects/Adverse Reactions 783
Occasional 783
Rare 783
Precautions and Contraindications 783
Caution: 783
Drug Interactions of Concern to Dentistry 783
Serious Reactions 783
Dental Considerations 783
General: 783
Consultations: 784
Teach Patient/Family to: 784
lixisenatide 784
Category and Schedule 784
Drug Class: 784
Mechanism of Action 784
Uses 784
Pharmacokinetics 784
Indications and Dosages 784
► Diabetes Mellitus, Type 2 784
Adults. 784
Side Effects/Adverse Reactions 784
Frequent 784
Occasional 784
Precautions and Contraindications 784
Drug Interactions of Concern to Dentistry 785
Serious Reactions 785
Dental Considerations 785
General: 785
Consultations: 785
Teach Patient/Family to: 785
lodoxamide 785
Category and Schedule 785
Drug Class: 785
Mechanism of Action 785
Uses 785
Pharmacokinetics 785
Indications and Dosages 785
► Treatment of Vernal Keratoconjunctivitis, Conjunctivitis, and Keratitis 785
Ophthalmic 785
Adults, Elderly, Children 2 yr or older. 785
Side Effects/Adverse Reactions 785
Frequent 785
Occasional 786
Rare 786
Precautions and Contraindications 786
Caution: 786
Drug Interactions of Concern to Dentistry 786
Serious Reactions 786
Dental Considerations 786
General: 786
Teach Patient/Family to: 786
lomefloxacin hydrochloride 786
Category and Schedule 786
Drug Class: 786
Mechanism of Action 786
Uses 786
Pharmacokinetics 786
Indications and Dosages 786
► Complicated UTIs 786
PO 786
Adults, Elderly. 786
► Uncomplicated UTIs 787
Side Effects/Adverse Reactions 787
Occasional 787
Rare 787
Precautions and Contraindications 787
Caution: 787
Drug Interactions of Concern to Dentistry 787
Serious Reactions 787
Dental Considerations 787
General: 787
Consultations: 787
Teach Patient/Family to: 787
lomustine 788
Category and Schedule 788
Drug Class: 788
Mechanism of Action 788
Uses 788
Pharmacokinetics 788
Indications and Dosages 788
► Disseminated Hodgkin’s Disease, Primary and Metastatic Brain Tumors 788
PO 788
Adults, Elderly. 788
Children. 788
Side Effects/Adverse Reactions 788
Frequent 788
Occasional 788
Precautions and Contraindications 788
Caution: 788
Drug Interactions of Concern to Dentistry 788
Serious Reactions 788
Dental Considerations 789
General: 789
Consultations: 789
Teach Patient/Family to: 789
loperamide hydrochloride 789
Category and Schedule 789
Drug Class: 789
Mechanism of Action 789
Uses 789
Pharmacokinetics 789
Indications and Dosages 790
► Acute Diarrhea 790
PO (Capsules) 790
Side Effects/Adverse Reactions 790
Frequent 790
Rare 790
Precautions and Contraindications 790
Caution: 790
Drug Interactions of Concern to Dentistry 790
Serious Reactions 790
Dental Considerations 790
General: 790
Teach Patient/Family: 790
loracarbef 791
Category and Schedule 791
Drug Class: 791
Mechanism of Action 791
Uses 791
Pharmacokinetics 791
Indications and Dosages 791
► Bronchitis 791
Side Effects/Adverse Reactions 791
Frequent 791
Occasional 791
Rare 791
Precautions and Contraindications 791
Caution: 791
Drug Interactions of Concern to Dentistry 792
Serious Reactions 792
Dental Considerations 792
General: 792
Consultations: 792
Teach Patient/Family to: 792
loratadine 792
Category and Schedule 792
Drug Class: 792
Mechanism of Action 792
Uses 792
Pharmacokinetics 792
Indications and Dosages 793
► Allergic Rhinitis, Urticaria 793
PO 793
Adults, Elderly, Children 6 yr and older. 793
Children 2–5 yr. 793
► Dosage in Hepatic Impairment 793
Side Effects/Adverse Reactions 793
Frequent 793
Occasional 793
Rare 793
Precautions and Contraindications 793
Caution: 793
Drug Interactions of Concern to Dentistry 793
Serious Reactions 793
Dental Considerations 793
General: 793
Teach Patient/Family to: 793
lorazepam 793
Category and Schedule 793
Drug Class: 793
Mechanism of Action 793
Uses 794
Pharmacokinetics 794
Indications and Dosages 794
► Anxiety 794
Side Effects/Adverse Reactions 794
Frequent 794
Occasional 794
Rare 794
Precautions and Contraindications 794
Caution: 794
Drug Interactions of Concern to Dentistry 794
Serious Reactions 794
Dental Considerations 795
General: 795
Consultations: 795
Teach Patient/Family to: 795
lorcaserin 795
Category and Schedule 795
Drug Class: 795
Mechanism of Action 795
Uses 795
Pharmacokinetics 795
Indications and Dosages 795
► Weight management 795
PO 795
Adults. 795
Side Effects/Adverse Reactions 795
Frequent 795
Occasional 795
Precautions and Contraindications 796
Drug Interactions of Concern to Dentistry 796
Serious Reactions 796
Dental Considerations 796
General: 796
Consultations: 796
Teach Patient/Family to: 796
losartan 797
Category and Schedule 797
Drug Class: 797
Mechanism of Action 797
Uses 797
Pharmacokinetics 797
Indications and Dosages 797
► Hypertension 797
Side Effects/Adverse Reactions 797
Frequent 797
Occasional 797
Rare 797
Precautions and Contraindications 797
Caution: 797
Drug Interactions of Concern to Dentistry 797
Serious Reactions 798
Dental Considerations 798
General: 798
Consultations: 798
Teach Patient/Family to: 798
loteprednol etabonate; tobramycin 798
Category and Schedule 798
Drug Class: 798
Mechanism of Action 798
Uses 798
Pharmacokinetics 798
Indications and Dosages 799
► Steroid-Responsive Inflammatory Ocular Conditions for Which a Corticosteroid is Indicated and Where Superficial Bacterial Ocular Infection or a Risk of Bacterial Ocular Infection Exists 799
Ophthalmic 799
Adults, Elderly. 799
Side Effects/Adverse Reactions 799
Frequent 799
Occasional 799
Rare 799
Precautions and Contraindications 799
Drug Interactions of Concern to Dentistry 799
Serious Reactions 799
Dental Considerations 799
General: 799
lovastatin 799
Category and Schedule 799
Drug Class: 799
Mechanism of Action 799
Uses 800
Pharmacokinetics 800
Indications and Dosages 800
► Hyperlipoproteinemia, Primary Prevention of Coronary Artery Disease 800
Side Effects/Adverse Reactions 800
Frequent 800
Occasional 800
Rare 800
Precautions and Contraindications 800
Caution: 800
Drug Interactions of Concern to Dentistry 800
Serious Reactions 800
Dental Considerations 800
General: 800
Teach Patient/Family to: 800
loxapine 801
Category and Schedule 801
Drug Class: 801
Mechanism of Action 801
Uses 801
Pharmacokinetics 801
Indications and Dosages 801
► Psychotic Disorders 801
PO 801
Adults. 801
Side Effects/Adverse Reactions 801
Frequent 801
Occasional 801
Precautions and Contraindications 801
Caution: 801
Drug Interactions of Concern to Dentistry 801
Serious Reactions 801
Dental Considerations 802
General: 802
Consultations: 802
Teach Patient/Family to: 802
lucinactant 802
Category and Schedule 802
Drug Class: 802
Mechanism of Action 802
Uses 802
Pharmacokinetics 802
lurasidone 803
Category and Schedule 803
Drug Class: 803
Mechanism of Action 803
Uses 803
Pharmacokinetics 803
Indications and Dosages 803
► Respiratory Distress Prophylaxis 803
Endotracheal 803
Premature infants. 803
Side Effects/Adverse Reactions 803
Frequent 803
Occasional 803
Precautions and Contraindications 803
Drug Interactions of Concern to Dentistry 803
Serious Reactions 803
Dental Considerations 803
General: 803
Consultations: 803
► Schizophrenia 803
PO 803
Adults. 803
► Dosage in Renal Impairment 803
► Dosage in Hepatic Impairment 804
Side Effects/Adverse Reactions 804
Frequent 804
Occasional 804
Precautions and Contraindications 804
Drug Interactions of Concern to Dentistry 804
Serious Reactions 804
Dental Considerations 804
General: 804
Consultations: 804
Teach Patient/Family to: 804
mafenide 805
Category and Schedule 805
Drug Class: 805
Mechanism of Action 805
Uses 805
Pharmacokinetics 805
Indications and Dosages 805
► Burns 805
Topical 805
Adults, Elderly, Children. 805
Side Effects/Adverse Reactions 805
Frequent 805
Occasional 805
Rare 805
Precautions and Contraindications 805
Drug Interactions of Concern to Dentistry 805
Serious Reactions 805
Dental Considerations 805
General: 805
Consultations: 805
Teach Patient/Family to: 805
magaldrate 806
Category and Schedule 806
Drug Class: 806
Mechanism of Action 806
Uses 806
Pharmacokinetics 806
Indications and Dosages 806
► Hyperacidity and Gas 806
PO 806
Adults, Elderly. 806
Side Effects/Adverse Reactions 806
Rare 806
Precautions and Contraindications 806
Caution: 806
Drug Interactions of Concern to Dentistry 806
Serious Reactions 806
Dental Considerations 806
General: 806
Uses 807
Pharmacokinetics 807
Indications and Dosages 807
► Mild-to-Moderate Depression 807
maprotiline 806
mebendazole 808
Category and Schedule 808
Drug Class: 808
Mechanism of Action 808
Uses 808
Pharmacokinetics 809
Indications and Dosages 809
► Trichuriasis, Ascariasis, Hookworm 809
mecasermin 809
Category and Schedule 809
Drug Class: 809
Mechanism of Action 809
Uses 809
Pharmacokinetics 810
Indications and Dosages 810
► Primary IGF-1 Deficiency (Severe) 810
SC 810
Children. 810
Side Effects/Adverse Reactions 810
Occasional 810
Rare 810
Precautions and Contraindications 810
Caution: 810
Drug Interactions of Concern to Dentistry 810
Serious Reactions 810
Dental Considerations 810
General: 810
meclizine 810
Category and Schedule 810
Drug Class: 810
Mechanism of Action 810
Uses 811
Pharmacokinetics 811
Indications and Dosages 811
► Motion Sickness 811
meclofenamate sodium 812
Category and Schedule 812
Drug Class: 812
Mechanism of Action 812
Uses 812
Pharmacokinetics 812
Indications and Dosages 812
► Mild-to-Moderate Pain 812
medroxyprogesterone acetate 813
Category and Schedule 813
Drug Class: 813
Mechanism of Action 814
Uses 814
Pharmacokinetics 814
Indications and Dosages 814
► Endometrial Hyperplasia 814
medrysone 815
Category and Schedule 815
Drug Class: 815
Mechanism of Action 815
Uses 815
Pharmacokinetics 815
Indications and Dosages 815
► Ophthalmic Disorders 815
Ophthalmic 815
Adults, Elderly, Children 3 yr and older. 815
Side Effects/Adverse Reactions 815
Frequent 815
Occasional 815
Precautions and Contraindications 815
Drug Interactions of Concern to Dentistry 815
Serious Reactions 815
Dental Considerations 815
General: 815
Teach Patient/Family to: 815
mefenamic acid 816
Category and Schedule 816
Drug Class: 816
Mechanism of Action 816
Uses 816
Pharmacokinetics 816
Indications and Dosages 816
► Mild-to-Moderate Pain, Lower Back Pain, Dysmenorrhea 816
PO 816
Adults, Elderly, Children 14 yr and older. 816
Side Effects/Adverse Reactions 816
Occasional 816
Rare 816
Precautions and Contraindications 816
Caution: 816
Drug Interactions of Concern to Dentistry 816
Serious Reactions 816
Dental Considerations 817
General: 817
Consultations: 817
Teach Patient/Family to: 817
mefloquine 817
Category and Schedule 817
Drug Class: 817
Mechanism of Action 817
Uses 817
Pharmacokinetics 817
Indications and Dosages 817
► Suppression of Malaria 817
PO 817
Adults. 817
Children more than 45 kg. 817
Children 30–45 kg. 817
Children 20–30 kg. 817
Children 10–20 kg. 817
► Treatment of Malaria 818
PO 818
Adults. 818
Children. 818
Side Effects/Adverse Reactions 818
Occasional 818
Rare 818
Precautions and Contraindications 818
Drug Interactions of Concern to Dentistry 818
Serious Reactions 818
Dental Considerations 818
General: 818
Consultations: 818
Teach Patient/Family to: 818
megestrol acetate 818
Category and Schedule 818
Drug Class: 818
Mechanism of Action 818
Uses 818
meloxicam 819
Category and Schedule 819
Drug Class: 819
Mechanism of Action 819
Uses 819
Pharmacokinetics 819
Indications and Dosages 819
► Palliative Treatment of Advanced Breast Cancer 819
► Osteoarthritis, Rheumatoid Arthritis 819
PO 819
Adults, Elderly. 819
► Palliative Treatment of Advanced Endometrial Carcinoma 819
► Anorexia, Cachexia, Weight Loss 819
Side Effects/Adverse Reactions 819
Frequent 819
Occasional 819
Rare 819
Precautions and Contraindications 819
Serious Reactions 819
Dental Considerations 819
General: 819
Teach Patient/Family to: 819
Adults. 819
Side Effects/Adverse Reactions 820
Frequent 820
Occasional 820
Rare 820
Precautions and Contraindications 820
Caution: 820
Drug Interactions of Concern to Dentistry 820
Serious Reactions 820
Dental Considerations 820
General: 820
Consultations: 820
Teach Patient/Family to: 820
melphalan 821
Category and Schedule 821
Drug Class: 821
Mechanism of Action 821
Uses 821
Pharmacokinetics 821
Indications and Dosages 821
► Ovarian Carcinoma 821
memantine + donepezil 822
Category and Schedule 822
Drug Class: 822
Mechanism of Action 822
Uses 822
Pharmacokinetics 823
Indications and Dosages 823
► Alzheimer Dementia (Moderate to Severe) 823
PO 823
Adults. 823
Side Effects/Adverse Reactions 823
Frequent 823
Occasional 823
Precautions and Contraindications 823
Drug Interactions of Concern to Dentistry 823
Serious Reactions 823
Dental Considerations 823
General: 823
Consultations: 824
Teach Patient/Family to: 824
memantine hydrochloride 824
Category and Schedule 824
Drug Class: 824
Mechanism of Action 824
Uses 824
Pharmacokinetics 824
Indications and Dosages 824
► Alzheimer’s Disease 824
PO 824
Adults, Elderly. 824
Side Effects/Adverse Reactions 824
Occasional 824
Rare 824
Precautions and Contraindications 824
Caution: 824
Drug Interactions of Concern to Dentistry 825
Serious Reactions 825
Dental Considerations 825
General: 825
Consultations: 825
Teach Patient/Family to: 825
meperidine hydrochloride 825
Category and Schedule 825
Drug Class: 825
Mechanism of Action 825
Uses 825
Pharmacokinetics 825
Indications and Dosages 826
► Analgesia 826
PO, IM, Subcutaneous 826
Adults, Elderly. 826
Children. 826
► Patient-Controlled Analgesia 826
IV 826
Adults. 826
► Dosage in Renal Impairment 826
Side Effects/Adverse Reactions 826
Frequent 826
Occasional 826
Rare 826
Precautions and Contraindications 826
Caution: 826
Drug Interactions of Concern to Dentistry 826
Serious Reactions 826
Dental Considerations 826
General: 826
Teach Patient/Family to: 826
mephentermine sulfate 827
Category and Schedule 827
Drug Class: 827
Mechanism of Action 827
Uses 827
Pharmacokinetics 827
Indications and Dosages 827
► Hypotension (Secondary to Spinal Anesthesia) 827
Uses 828
Pharmacokinetics 828
Indications and Dosages 828
► Epilepsy 828
mephobarbital 827
mepivacaine HCl 829
Category and Schedule 829
Drug Class: 829
Mechanism of Action 829
Uses 829
Pharmacokinetics 829
Indications and Dosages 829
► Regional Anesthesia 829
Side Effects/Adverse Reactions 830
Occasional 830
Rare 830
Precautions and Contraindications 830
Caution: 830
Drug Interactions of Concern to Dentistry 830
Serious Reactions 830
Dental Considerations 830
General: 830
Teach Patient/Family to: 830
meprobamate 831
Category and Schedule 831
Drug Class: 831
Mechanism of Action 831
Uses 831
Pharmacokinetics 831
Indications and Dosages 831
► Anxiety Disorders 831
PO 831
Adults, Children 12 yr and older. 831
Children 6–12 yr. 831
Elderly. 831
► Dosage in Renal Impairment 831
Side Effects/Adverse Reactions 831
Frequent 831
Occasional 831
Precautions and Contraindications 831
Caution: 831
Drug Interactions of Concern to Dentistry 831
Serious Reactions 831
Dental Considerations 831
General: 831
Consultations: 832
Teach Patient/Family to: 832
mercaptopurine (6-MP) 832
Category and Schedule 832
Drug Class: 832
Mechanism of Action 832
Uses 832
Pharmacokinetics 832
Indications and Dosages 832
► ALL 832
PO 832
Adults, Elderly, Children. 832
► Dosage in Renal Impairment 832
Side Effects/Adverse Reactions 832
Frequent 832
Occasional 832
Precautions and Contraindications 832
Caution: 832
Drug Interactions of Concern to Dentistry 833
Serious Reactions 833
Dental Considerations 833
General: 833
Consultations: 833
Teach Patient/Family to: 833
meropenem 833
Category and Schedule 833
Drug Class: 833
Mechanism of Action 833
Uses 833
Pharmacokinetics 833
Indications and Dosages 833
► Mild-to-Moderate Infections 833
mesalamine/ 5-aminosalicylic acid (5-ASA) 834
Category and Schedule 834
Drug Class: 834
Mechanism of Action 834
Uses 834
Pharmacokinetics 835
Indications and Dosages 835
► Ulcerative Colitis (Induction of Remission), Proctosigmoiditis, Proctitis 835
mesna 836
Category and Schedule 836
Drug Class: 836
Mechanism of Action 836
Uses 836
Pharmacokinetics 836
Indications and Dosages 836
► Prevention of Hemorrhagic Cystitis in Patients Receiving Ifosfamide 836
IV 836
Adults, Elderly. 836
► Prevention of Hemorrhagic Cystitis in Patients Receiving Cyclophosphamide 837
PO 837
mesoridazine besylate 837
Category and Schedule 837
Drug Class: 837
Mechanism of Action 837
Uses 838
Pharmacokinetics 838
Indications and Dosages 838
► Schizophrenia 838
metaproterenol sulfate 839
Category and Schedule 839
Drug Class: 839
Mechanism of Action 839
Uses 840
Pharmacokinetics 840
Indications and Dosages 840
► Treatment of Bronchospasm 840
PO 840
Adults, Children 10 yr and older. 840
Elderly. 840
Children 6–9 yr. 840
Children 2–5 yr. 840
Children younger than 2 yr. 840
Inhalation 840
metaraminol 841
Category and Schedule 841
Drug Class: 841
Mechanism of Action 841
Uses 841
Pharmacokinetics 841
Indications and Dosages 841
► Prevention of Hypotension 841
IM/Subcutaneous 841
metaxalone 842
Category and Schedule 842
Drug Class: 842
Mechanism of Action 842
Uses 842
Pharmacokinetics 842
Indications and Dosages 842
► Muscle Relaxant 842
PO 842
Adults, Elderly, Children older than 12 yr. 842
Side Effects/Adverse Reactions 842
Occasional 842
Precautions and Contraindications 842
Caution: 842
Drug Interactions of Concern to Dentistry 842
Serious Reactions 842
Dental Considerations 842
General: 842
Consultations: 843
Teach Patient/Family to: 843
metformin hydrochloride 843
Category and Schedule 843
Drug Class: 843
Mechanism of Action 843
Uses 843
Pharmacokinetics 843
Indications and Dosages 843
► Diabetes Mellitus 843
PO (500-mg, 1000-mg Tablet) 843
methadone hydrochloride 845
Category and Schedule 845
Drug Class: 845
Mechanism of Action 845
Uses 845
Pharmacokinetics 845
Indications and Dosages 845
► Analgesia 845
PO 845
methamphetamine 846
Category and Schedule 846
Drug Class: 846
Mechanism of Action 846
Uses 846
Pharmacokinetics 846
Indications and Dosages 846
► ADHD 846
PO 846
Adults, Children 6 yr and older. 846
► Appetite Suppressant 847
PO 847
Adults, Children 12 yr and older. 847
Side Effects/Adverse Reactions 847
Frequent 847
Occasional 847
Precautions and Contraindications 847
Caution: 847
Drug Interactions of Concern to Dentistry 847
Serious Reactions 847
Dental Considerations 847
General: 847
Consultations: 847
Teach Patient/Family to: 847
methazolamide 848
Category and Schedule 848
Drug Class: 848
Mechanism of Action 848
Uses 848
Pharmacokinetics 848
Indications and Dosages 848
► Glaucoma 848
PO 848
Adults, Elderly. 848
Side Effects/Adverse Reactions 848
Occasional 848
Rare 848
Precautions and Contraindications 848
Caution: 848
Drug Interactions of Concern to Dentistry 848
Methazolamide (Neptazane, GlaucTabs) 848
Serious Reactions 848
Dental Considerations 849
General: 849
Consultations: 849
Teach Patient/Family to: 849
methenamine 849
Category and Schedule 849
Drug Class: 849
Mechanism of Action 849
Uses 849
Pharmacokinetics 849
Indications and Dosages 849
► UTI 849
PO 849
Adults, Elderly. 849
Children 6–12 yr. 849
Side Effects/Adverse Reactions 849
Occasional 849
Rare 849
Precautions and Contraindications 849
Caution: 849
methimazole 850
Category and Schedule 850
Drug Class: 850
Mechanism of Action 850
Uses 850
Pharmacokinetics 850
Indications and Dosages 850
► Hyperthyroidism 850
PO 850
Adults, Elderly. 850
Children. 850
Side Effects/Adverse Reactions 850
Frequent 850
Occasional 850
Rare 850
Precautions and Contraindications 850
Caution: 850
Drug Interactions of Concern to Dentistry 850
Serious Reactions 850
Dental Considerations 850
General: 850
Teach Patient/Family to: 850
Serious Reactions 851
Dental Considerations 851
General: 851
Consultations: 851
Teach Patient/Family to: 851
methocarbamol 851
Category and Schedule 851
Drug Class: 851
Mechanism of Action 851
Uses 851
Pharmacokinetics 851
Indications and Dosages 851
► Musculoskeletal Spasm 851
IM/IV 851
methotrexate sodium 852
Category and Schedule 852
Drug Class: 852
Mechanism of Action 852
Uses 853
Pharmacokinetics 853
Indications and Dosages 853
► Trophoblastic Neoplasms 853
methoxy polyethylene glycol-epoetin beta 855
Category and Schedule 855
Drug Class: 855
Mechanism of Action 855
Uses 855
Pharmacokinetics 855
Indications and Dosages 855
► Patients Not Currently Treated with an Erythropoiesis Stimulating Agent (ESA) 855
methsuximide 856
Category and Schedule 856
Drug Class: 856
Mechanism of Action 856
Uses 856
Pharmacokinetics 856
Indications and Dosages 857
► Absence Seizures 857
PO 857
Adults, Elderly. 857
Children. 857
Side Effects/Adverse Reactions 857
Frequent 857
Occasional 857
Precautions and Contraindications 857
Caution: 857
Drug Interactions of Concern to Dentistry 857
Serious Reactions 857
Dental Considerations 857
General: 857
Consultations: 857
Teach Patient/Family to: 857
methyldopa/methyldopate 858
Category and Schedule 858
Drug Class: 858
Mechanism of Action 858
Uses 858
Pharmacokinetics 858
Indications and Dosages 858
► Moderate-to-Severe Hypertension 858
PO 858
methylergonovine 859
Category and Schedule 859
Drug Class: 859
Mechanism of Action 859
Uses 859
Pharmacokinetics 859
Indications and Dosages 860
► Prevention and Treatment of Postpartum and Postabortion Hemorrhage Caused by Atony or Involution 860
PO 860
methylphenidate hydrochloride 860
Category and Schedule 860
Drug Class: 860
Mechanism of Action 860
Uses 861
Pharmacokinetics 861
Indications and Dosages 861
► ADHD 861
methylprednisolone 862
Category and Schedule 862
Drug Class: 862
Mechanism of Action 862
Uses 862
Pharmacokinetics 862
Indications and Dosages 863
► Substitution Therapy for Deficiency States: Acute or Chronic Adrenal Insufficiency, Adrenal Insufficiency Secondary to Pituitary Insufficiency, and Congenital Adrenal Hyperplasia; Nonendocrine Disorders: Allergic, Collagen, Hepatic, Intestinal Tract, Ocular, Renal, and Skin Diseases; Arthritis; Bronchial Asthma; Cerebral Edema; Malignancies; and Rheumatic Carditis 863
PO 863
methyltestosterone 864
Category and Schedule 864
Drug Class: 864
Mechanism of Action 864
Uses 864
Pharmacokinetics 864
Indications and Dosages 865
► Breast Cancer 865
metipranolol hydrochloride 865
Category and Schedule 865
Drug Class: 865
Mechanism of Action 865
Uses 866
Pharmacokinetics 866
Indications and Dosages 866
► Glaucoma, Ocular Hypertension 866
Ophthalmic 866
Adults, Elderly. 866
Side Effects/Adverse Reactions 866
Frequent 866
Occasional 866
Rare 866
Precautions and Contraindications 866
Drug Interactions of Concern to Dentistry 866
Serious Reactions 866
Dental Considerations 866
General: 866
Consultations: 866
Teach Patient/Family to: 866
metoclopramide 866
Category and Schedule 866
Drug Class: 866
Mechanism of Action 867
Uses 867
Pharmacokinetics 867
Indications and Dosages 867
► Prevention of Chemotherapy-Induced Nausea and Vomiting 867
metolazone 868
Category and Schedule 868
Drug Class: 868
Mechanism of Action 868
Uses 869
Pharmacokinetics 869
Indications and Dosages 869
► Edema 869
metoprolol tartrate 870
Category and Schedule 870
Drug Class: 870
Mechanism of Action 870
Uses 870
Pharmacokinetics 870
Indications and Dosages 871
► Mild-to-Moderate Hypertension 871
metronidazole hydrochloride 873
Category and Schedule 873
Drug Class: 873
Mechanism of Action 873
Uses 873
Pharmacokinetics 873
Indications and Dosages 873
► Amebiasis 873
metyrosine 875
Category and Schedule 875
Drug Class: 875
Mechanism of Action 875
Uses 875
Pharmacokinetics 875
Indications and Dosages 875
► Pheochromocytoma (Preoperative) 875
PO 875
Adults, Elderly. 875
Side Effects/Adverse Reactions 875
Frequent 875
Occasional 875
Rare 875
Precautions and Contraindications 875
Drug Interactions of Concern to Dentistry 875
Serious Reactions 875
Dental Considerations 875
General: 875
Consultations: 876
Teach Patient/Family to: 876
mexiletine hydrochloride 876
Category and Schedule 876
Drug Class: 876
Mechanism of Action 876
Uses 876
Pharmacokinetics 876
Indications and Dosages 876
► Arrhythmia 876
PO 876
Adults, Elderly. 876
Side Effects/Adverse Reactions 876
Frequent 876
Occasional 876
Precautions and Contraindications 876
Caution: 876
Drug Interactions of Concern to Dentistry 876
Serious Reactions 877
Dental Considerations 877
General: 877
Consultations: 877
Teach Patient/Family to: 877
miconazole 877
Category and Schedule 877
Drug Class: 877
Mechanism of Action 877
Uses 877
Pharmacokinetics 877
Indications and Dosages 878
► Coccidioidomycosis 878
midazolam hydrochloride 879
Category and Schedule 879
Drug Class: 879
Mechanism of Action 879
Uses 879
Pharmacokinetics 879
Indications and Dosages 879
► Preoperative Sedation 879
PO 879
midodrine 881
Category and Schedule 881
Drug Class: 881
Mechanism of Action 881
Uses 881
Pharmacokinetics 881
Indications and Dosages 881
► Orthostatic Hypotension 881
PO 881
mifepristone 882
Category and Schedule 882
Drug Class: 882
Mechanism of Action 882
Uses 882
Pharmacokinetics 882
Indications and Dosages 882
► Hyperglycemia in Patients with Cushing’s Syndrome 882
PO 882
Adults. 882
Dosage in Renal Impairment. 882
Dosage in Hepatic Impairment. 883
Side Effects/Adverse Reactions 883
Frequent 883
Occasional 883
Precautions and Contraindications 883
Drug Interactions of Concern to Dentistry 883
Serious Reactions 883
Dental Considerations 883
General: 883
Consultations: 883
Teach Patient/Family to: 884
miglitol 884
Category and Schedule 884
Drug Class: 884
Mechanism of Action 884
Uses 884
Pharmacokinetics 884
Indications and Dosages 884
► Diabetes Mellitus 884
PO 884
Adults, Elderly. 884
Side Effects/Adverse Reactions 884
Frequent 884
Occasional 884
Precautions and Contraindications 884
Caution: 884
Drug Interactions of Concern to Dentistry 884
Dental Considerations 884
General: 884
Consultations: 885
Teach Patient/Family to: 885
miglustat 885
Category and Schedule 885
Drug Class: 885
Mechanism of Action 885
Uses 885
Pharmacokinetics 885
Indications and Dosages 885
► Gaucher’s Disease 885
PO 885
Adults, Elderly. 885
► Dosage in Renal Impairment 885
Patients with creatinine clearance of 50–70 ml/min. 885
Patients with creatinine clearance of 30–49 ml/min. 885
Side Effects/Adverse Reactions 885
Expected 885
Frequent 885
Occasional 885
Precautions and Contraindications 885
Caution: 885
Drug Interactions of Concern to Dentistry 886
Serious Reactions 886
Dental Considerations 886
General: 886
Consultations: 886
Teach Patient/Family to: 886
milnacipran 886
Category and Schedule 886
Drug Class: 886
Mechanism of Action 886
Uses 886
Pharmacokinetics 886
Indications and Dosages 886
► Fibromyalgia 886
PO 886
Adults, Elderly. 886
Side Effects/Adverse Reactions 887
Frequent 887
Occasional 887
Rare 887
Precautions and Contraindications 887
Caution: 887
Drug Interactions of Concern to Dentistry 887
Serious Reactions 887
Dental Considerations 887
General: 887
Teach Patient/Family: 887
minocycline hydrochloride 888
Category and Schedule 888
Drug Class: 888
Mechanism of Action 888
Uses 888
Pharmacokinetics 888
Indications and Dosages 888
► Mild, Moderate, or Severe Prostate, Urinary Tract, and CNS Infections (excluding meningitis); Uncomplicated Gonorrhea; Inflammatory Acne; Brucellosis; Skin Granulomas; Cholera; Trachoma; Nocardiasis; Yaws; and Syphilis When Penicillins Are Contraindicated 888
PO 888
minoxidil 890
Category and Schedule 890
Drug Class: 890
Mechanism of Action 890
Uses 890
Pharmacokinetics 890
Indications and Dosages 890
► Severe Symptomatic Hypertension, Hypertension Associated with Organ Damage, Hypertension That Has Failed to Respond to Maximal Therapeutic Dosages of a Diuretic or Two Other Antihypertensives 890
PO 890
mipomersen 891
Category and Schedule 891
Drug Class: 891
Mechanism of Action 891
Uses 892
Pharmacokinetics 892
Indications and Dosages 892
► Homozygous Familial Hypercholesterolemia (HoFH) 892
Adults. 892
Side Effects/Adverse Reactions 892
Frequent 892
Occasional 892
Precautions and Contraindications 892
Drug Interactions of Concern to Dentistry 892
Serious Reactions 892
Dental Considerations 892
General: 892
Consultations: 892
Teach Patient/Family to: 892
mirtazapine 893
Category and Schedule 893
Drug Class: 893
Mechanism of Action 893
Uses 893
Pharmacokinetics 893
Indications and Dosages 893
► Depression 893
PO 893
Adults. 893
Elderly. 893
Side Effects/Adverse Reactions 893
Frequent 893
Occasional 893
Rare 893
Precautions and Contraindications 893
Caution: 893
Drug Interactions of Concern to Dentistry 893
Serious Reactions 893
Dental Considerations 894
General: 894
Consultations: 894
Teach Patient/Family to: 894
misoprostol 894
Category and Schedule 894
Drug Class: 894
Mechanism of Action 894
Uses 894
Pharmacokinetics 894
mitotane 895
Category and Schedule 895
Drug Class: 895
Mechanism of Action 895
Uses 895
Pharmacokinetics 895
Indications and Dosages 895
► Prevention of NSAID-Induced Gastric Ulcer 895
► Adrenocortical Carcinomas 895
PO 895
Adults. 895
Elderly. 895
Adults, Elderly. 895
Side Effects/Adverse Reactions 895
Frequent 895
Occasional 895
Rare 895
Precautions and Contraindications 895
Caution: 895
Serious Reactions 895
Dental Considerations 895
General: 895
Consultations: 895
Precautions and Contraindications 896
Caution: 896
Drug Interactions of Concern to Dentistry 896
Serious Reactions 896
Dental Considerations 896
General: 896
Consultations: 896
Teach Patient/Family to: 896
mitoxantrone 896
Category and Schedule 896
Drug Class: 896
Mechanism of Action 896
modafinil 898
Category and Schedule 898
Drug Class: 898
Mechanism of Action 898
Uses 898
Pharmacokinetics 898
Indications and Dosages 898
► Narcolepsy, Other Sleep Disorders 898
PO 898
Adults, Elderly. 898
Side Effects/Adverse Reactions 898
Frequent 898
Occasional 899
Precautions and Contraindications 899
Caution: 899
Drug Interactions of Concern to Dentistry 899
Serious Reactions 899
Dental Considerations 899
General: 899
Teach Patient/Family to: 899
moexipril hydrochloride 899
Category and Schedule 899
Drug Class: 899
Mechanism of Action 899
Uses 899
Pharmacokinetics 899
Indications and Dosages 900
► Hypertension 900
molindone 901
Category and Schedule 901
Drug Class: 901
Mechanism of Action 901
Uses 901
Pharmacokinetics 901
Indications and Dosages 901
► Schizophrenia 901
PO 901
Adults, Children 12 yr and older. 901
Elderly. 901
Side Effects/Adverse Reactions 901
Frequent 901
Occasional 901
Rare 901
Precautions and Contraindications 902
Caution: 902
Drug Interactions of Concern to Dentistry 902
Serious Reactions 902
Dental Considerations 902
General: 902
Consultations: 902
Teach Patient/Family to: 902
mometasone furoate monohydrate 902
Category and Schedule 902
Drug Class: 902
Mechanism of Action 903
Uses 903
Pharmacokinetics 903
Indications and Dosages 903
► Allergic Rhinitis 903
mometasone furoate + formoterol fumarate 904
Category and Schedule 904
Drug Class: 904
Mechanism of Action 904
Uses 904
Pharmacokinetics 904
Indications and Dosages 904
► Asthma 904
Oral Inhalation 904
Adults, Children 12 yr and older. 904
Side Effects/Adverse Reactions 904
Frequent 904
Occasional 904
Precautions and Contraindications 904
Drug Interactions of Concern to Dentistry 905
Serious Reactions 905
Dental Considerations 905
General: 905
Consultations: 905
Teach Patient/Family to: 905
montelukast 905
Category and Schedule 905
Drug Class: 905
Mechanism of Action 905
Uses 905
Pharmacokinetics 906
Indications and Dosages 906
► Bronchial Asthma 906
PO 906
Adults, Elderly, Adolescents older than 14 yr. 906
Children 6–14 yr. 906
Children 1–5 yr. 906
Side Effects/Adverse Reactions 906
Adults, Adolescents 15 yr and older 906
Frequent 906
Occasional 906
moricizine hydrochloride 907
Category and Schedule 907
Drug Class: 907
Mechanism of Action 907
Uses 907
Pharmacokinetics 907
Indications and Dosages 907
► Arrhythmias 907
PO 907
Adults, Elderly. 907
Side Effects/Adverse Reactions 907
Frequent 907
Occasional 907
Precautions and Contraindications 907
Caution: 907
Drug Interactions of Concern to Dentistry 907
Serious Reactions 907
Dental Considerations 907
General: 907
Consultations: 908
Teach Patient/Family to: 908
morphine sulfate 908
Category and Schedule 908
Drug Class: 908
Mechanism of Action 908
Uses 908
Pharmacokinetics 908
Indications and Dosages 908
moxifloxacin hydrochloride 910
Category and Schedule 910
Drug Class: 910
Mechanism of Action 910
Uses 910
Pharmacokinetics 911
Indications and Dosages 911
► Acute Bacterial Sinusitis, Community-Acquired Pneumonia 911
mupirocin 912
Category and Schedule 912
Drug Class: 912
Mechanism of Action 912
Uses 912
Pharmacokinetics 912
Indications and Dosages 912
► Impetigo, Infected Traumatic Skin Lesions 912
Topical 912
Adults, Elderly, Children. 912
► Nasal Colonization of Resistant Staphylococcus Aureus 912
Intranasal 912
Adults, Elderly, Children 12 yr and older. 912
Side Effects/Adverse Reactions 913
Frequent 913
Occasional 913
Rare 913
Precautions and Contraindications 913
Caution: 913
Drug Interactions of Concern to Dentistry 913
Serious Reactions 913
Dental Considerations 913
General: 913
mycophenolate mofetil 913
Category and Schedule 913
Drug Class: 913
Mechanism of Action 913
Uses 913
Pharmacokinetics 913
Indications and Dosages 913
► Prevention of Renal Transplant Rejection 913
PO, IV 913
Adults, Elderly. 913
► Prevention of Heart Transplant Rejection 914
PO, IV 914
nabumetone 916
Category and Schedule 916
Drug Class: 916
Mechanism of Action 916
Uses 916
Pharmacokinetics 916
Indications and Dosages 916
► Acute or Chronic Rheumatoid Arthritis and Osteoarthritis 916
PO 916
Adults, Elderly. 916
Side Effects/Adverse Reactions 916
Frequent 916
Occasional 916
Rare 916
Precautions and Contraindications 916
Caution: 916
Drug Interactions of Concern to Dentistry 916
Serious Reactions 916
Dental Considerations 917
General: 917
Consultations: 917
Teach Patient/Family to: 917
nadolol 917
Category and Schedule 917
Drug Class: 917
Mechanism of Action 917
Uses 917
Pharmacokinetics 917
Indications and Dosages 918
► Mild-to-Moderate Hypertension, Angina 918
PO 918
Adults. 918
Elderly. 918
► Dosage in Renal Impairment 918
Side Effects/Adverse Reactions 918
Frequent 918
Occasional 918
Rare 918
Precautions and Contraindications 918
Caution: 918
Drug Interactions of Concern to Dentistry 918
Serious Reactions 918
Dental Considerations 918
General: 918
Consultations: 919
Teach Patient/Family to: 919
nafarelin 919
Category and Schedule 919
Drug Class: 919
Mechanism of Action 919
Uses 919
Pharmacokinetics 919
Indications and Dosages 919
► Endometriosis 919
Intranasal 919
Adults. 919
► Central Precocious Puberty 920
Intranasal 920
Children. 920
naftifine 920
Category and Schedule 920
Drug Class: 920
Mechanism of Action 920
Uses 920
Pharmacokinetics 920
Indications and Dosages 920
► Tinea Pedis, Tinea Cruris, Tinea Corporis 920
Topical 920
Adults, Elderly, Children 12 yr and older. 920
Side Effects/Adverse Reactions 920
Frequent 920
Occasional 920
Rare 920
Precautions and Contraindications 920
Drug Interactions of Concern to Dentistry 920
Serious Reactions 920
Dental Considerations 920
General: 920
nalbuphine hydrochloride 921
Category and Schedule 921
Drug Class: 921
Mechanism of Action 921
Uses 921
Pharmacokinetics 921
Indications and Dosages 921
► Analgesia 921
IV, IM, Subcutaneous 921
nalmefene hydrochloride 922
Category and Schedule 922
Drug Class: 922
Mechanism of Action 922
Uses 923
Pharmacokinetics 923
Indications and Dosages 923
► Reversal of Opioid Depression 923
naloxegol 924
Category and Schedule 924
Drug Class: 924
Mechanism of Action 924
Uses 924
Pharmacokinetics 924
Indications and Dosages 924
► Opioid-Induced Constipation 924
PO 924
Adults. 924
Side Effects/Adverse Reactions 924
Frequent 924
Occasional 924
Precautions and Contraindications 924
Drug Interactions of Concern to Dentistry 924
Serious Reactions 925
Dental Considerations 925
General: 925
Consultations: 925
Teach Patient/Family to: 925
naloxone hydrochloride 925
Category and Schedule 925
Drug Class: 925
Mechanism of Action 925
Uses 925
Pharmacokinetics 925
Indications and Dosages 926
► Opioid Toxicity 926
IV, IM, Subcutaneous 926
Adults, Elderly. 926
Children 5 yr and older and weighing 22 kg or more. 926
Children younger than 5 yr and weighing less than 22 kg. 926
► Postanesthesia Narcotic Reversal 926
naltrexone + bupropion 927
Category and Schedule 927
Drug Class: 927
Mechanism of Action 927
Uses 927
Pharmacokinetics 927
Indications and Dosages 927
► Chronic Weight Management 927
PO 927
Adults. 927
Side Effects/Adverse Reactions 927
Frequent 927
Occasional 928
Precautions and Contraindications 928
Drug Interactions of Concern to Dentistry 928
Serious Reactions 928
Dental Considerations 928
General: 928
Consultations: 928
Teach Patient/Family to: 928
naltrexone hydrochloride 929
Category and Schedule 929
Drug Class: 929
Mechanism of Action 929
Uses 929
Pharmacokinetics 929
Indications and Dosages 929
► Naloxone Challenge Test to Determine if Patient is Opioid Dependent 929
Alert 929
IV 929
naproxen/naproxen sodium 930
Category and Schedule 930
Drug Class: 930
Mechanism of Action 930
Uses 931
Pharmacokinetics 931
Indications and Dosages 931
► Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis 931
naproxen + esomeprazole 932
Category and Schedule 932
Drug Class: 932
Mechanism of Action 933
Uses 933
Pharmacokinetics 933
Indications and Dosages 933
Reduce NSAID-Associated Gastric Ulcers During Treatment for Arthritis 933
PO 933
Adults. 933
Side Effects/Adverse Reactions 933
Frequent 933
Occasional 933
Precautions and Contraindications 933
Drug Interactions of Concern to Dentistry 933
Serious Reactions 934
Dental Considerations 934
General: 934
Consultations: 934
Teach Patient/Family to: 934
naratriptan 934
Category and Schedule 934
Drug Class: 934
Mechanism of Action 934
Uses 934
Pharmacokinetics 935
Indications and Dosages 935
► Acute Migraine Attack 935
PO 935
Adults. 935
► Dosage in Mild-to-Moderate Hepatic or Renal Impairment 935
Side Effects/Adverse Reactions 935
Occasional 935
Rare 935
Precautions and Contraindications 935
Caution: 935
Drug Interactions of Concern to Dentistry 935
Serious Reactions 935
Dental Considerations 935
General: 935
Consultations: 935
Teach Patient/Family to: 935
nateglinide 936
Category and Schedule 936
Drug Class: 936
Mechanism of Action 936
Uses 936
Pharmacokinetics 936
Indications and Dosages 936
► Diabetes Mellitus 936
PO 936
Adult, Elderly. 936
Side Effects/Adverse Reactions 936
Frequent 936
Occasional 936
Rare 936
Precautions and Contraindications 936
Caution: 936
Drug Interactions of Concern to Dentistry 936
Serious Reactions 936
Dental Considerations 937
General: 937
Consultations: 937
Teach Patient/Family to: 937
nebivolol 937
Category and Schedule 937
Drug Class: 937
Mechanism of Action 937
Uses 937
Pharmacokinetics 937
Indications and Dosages 937
► Hypertension 937
PO 937
Adults, Elderly. 937
► Dosage in Renal Impairment 937
Adults (creatinine clearance less than 30 ml/min). 937
► Dosage in Hepatic Impairment (Moderate) 937
Adults. 937
Side Effects/Adverse Reactions 938
Adults 938
Frequent 938
Occasional 938
Rare 938
Precautions and Contraindications 938
Caution: 938
Drug Interactions of Concern to Dentistry 938
Serious Reactions 938
Dental Considerations 938
General: 938
Consultations: 939
Teach Patient/Family to: 939
nebivolol + valsartan 939
Category and Schedule 939
Drug Class: 939
Mechanism of Action 939
Uses 939
Pharmacokinetics 939
Indications and Dosages 939
► Hypertension 939
PO 939
Adults. 939
Side Effects/Adverse Reactions 940
Frequent 940
Occasional 940
Precautions and Contraindications 940
Drug Interactions of Concern to Dentistry 940
Serious Reactions 940
Dental Considerations 940
General: 940
Consultations: 940
Teach Patient/Family to: 940
nedocromil sodium 940
Category and Schedule 940
Drug Class: 940
Mechanism of Action 941
Uses 941
Pharmacokinetics 941
Indications and Dosages 941
► Mild-to-Moderate Asthma 941
Oral Inhalation 941
Adults, Elderly, Children 6 yr and older. 941
► Allergic Conjunctivitis 941
Ophthalmic 941
Adults, Elderly, Children 3 yr and older. 941
Side Effects/Adverse Reactions 941
Frequent 941
Occasional 941
Rare 941
Precautions and Contraindications 941
Caution: 941
Drug Interactions of Concern to Dentistry 941
Serious Reactions 941
Dental Considerations 941
Nedocromil Sodium (Alocril) 941
nefazodone hydrochloride 942
Category and Schedule 942
Drug Class: 942
Mechanism of Action 942
Uses 942
Pharmacokinetics 942
Indications and Dosages 942
► Depression, Prevention of Relapse of Acute Depressive Episode 942
PO 942
Adults. 942
Elderly. 942
Children. 942
Side Effects/Adverse Reactions 942
Frequent 942
Occasional 942
Precautions and Contraindications 942
Caution: 942
Drug Interactions of Concern to Dentistry 942
Serious Reactions 942
Dental Considerations 943
General: 943
Consultations: 943
Teach Patient/Family to: 943
nelarabine 943
Category and Schedule 943
Drug Class: 943
Mechanism of Action 943
Uses 943
Pharmacokinetics 943
Indications and Dosages 943
► T-cell ALL (Relapsed or Refractory) 943
IV 943
Adults. 943
nelfinavir 945
Category and Schedule 945
Drug Class: 945
Mechanism of Action 945
Uses 945
Pharmacokinetics 945
Indications and Dosages 945
► HIV Infection 945
PO 945
Adults. 945
Children 2–13 yr. 946
Side Effects/Adverse Reactions 946
Frequent 946
Occasional 946
Rare 946
Precautions and Contraindications 946
Caution: 946
Drug Interactions of Concern to Dentistry 946
Serious Reactions 946
Dental Considerations 946
General: 946
Consultations: 946
Teach Patient/Family to: 946
neostigmine 946
Category and Schedule 946
Drug Class: 946
Mechanism of Action 947
Uses 947
Pharmacokinetics 947
Indications and Dosages 947
► Myasthenia Gravis 947
PO 947
netupitant + palonosetron 948
Category and Schedule 948
Drug Class: 948
Mechanism of Action 948
Uses 948
Pharmacokinetics 948
Indications and Dosages 949
► Prevention of Acute and Delayed Cancer Chemotherapy–Induced Nausea and Vomiting 949
PO 949
Adults. 949
Side Effects/Adverse Reactions 949
Frequent 949
Occasional 949
Precautions and Contraindications 949
Drug Interactions of Concern to Dentistry 949
Serious Reactions 949
Dental Considerations 949
General: 949
Consultations: 949
Teach Patient/Family to: 949
nevirapine 949
Category and Schedule 949
Drug Class: 949
Mechanism of Action 950
Uses 950
Pharmacokinetics 950
Indications and Dosages 950
► HIV Infection 950
PO 950
Adults. 950
Children older than 8 yr. 950
Children 2 mo–8 yr. 950
Side Effects/Adverse Reactions 950
Frequent 950
Occasional 950
Rare 950
Precautions and Contraindications 950
Caution: 950
Drug Interactions of Concern to Dentistry 950
Serious Reactions 950
Dental Considerations 950
General: 950
Consultations: 950
Teach Patient/Family to: 950
niacin, nicotinic acid 951
Category and Schedule 951
Drug Class: 951
Mechanism of Action 951
Uses 951
Pharmacokinetics 951
Indications and Dosages 951
► Hyperlipidemia 951
PO (Immediate-Release) 951
nicardipine hydrochloride 952
Category and Schedule 952
Drug Class: 952
Mechanism of Action 952
Uses 952
Pharmacokinetics 952
Indications and Dosages 953
► Chronic Stable (Effort-Associated) Angina 953
nicotine 954
Category and Schedule 954
Drug Class: 954
Mechanism of Action 954
Uses 954
Pharmacokinetics 954
Indications and Dosages 955
► Smoking Cessation Aid to Relieve Nicotine Withdrawal Symptoms 955
PO (Chewing Gum) 955
nifedipine 956
Category and Schedule 956
Drug Class: 956
Mechanism of Action 957
Uses 957
Pharmacokinetics 957
Indications and Dosages 957
► Prinzmetal’s Variant Angina, Chronic Stable (Effort-Associated) Angina 957
PO 957
nilotinib 958
Category and Schedule 958
Drug Class: 958
Mechanism of Action 958
Uses 958
Pharmacokinetics 958
Indications and Dosages 958
PO 958
Adults. 958
Side Effects/Adverse Reactions 959
Adult 959
Frequent 959
Occasional 959
Precautions and Contraindications 959
Drug Interactions of Concern to Dentistry 960
Serious Reactions 960
Dental Considerations 960
General: 960
Consultations: 960
Teach Patient/Family to: 960
nilutamide 960
Category and Schedule 960
Drug Class: 960
Mechanism of Action 960
Uses 960
Pharmacokinetics 960
Indications and Dosages 960
► Prostatic Carcinoma 960
PO 960
Adults, Elderly. 960
Side Effects/Adverse Reactions 960
Frequent 960
Occasional 961
Precautions and Contraindications 961
Drug Interactions of Concern to Dentistry 961
Serious Reactions 961
Dental Considerations 961
General: 961
Consultations: 961
Teach Patient/Family to: 961
nimodipine 961
Category and Schedule 961
Drug Class: 961
Mechanism of Action 961
Uses 961
Pharmacokinetics 962
Indications and Dosages 962
► Improvement in Neurologic Deficits after Subarachnoid Hemorrhage from Ruptured Congenital Aneurysms 962
PO 962
Adults, Elderly. 962
Side Effects/Adverse Reactions 962
Occasional 962
Rare 962
Precautions and Contraindications 962
Drug Interactions of Concern to Dentistry 962
Serious Reactions 962
Dental Considerations 962
General: 962
Consultations: 962
Teach Patient/Family to: 962
nintedanib 962
Category and Schedule 962
Drug Class: 962
Mechanism of Action 963
Uses 963
Pharmacokinetics 963
Indications and Dosages 963
► Idiopathic Pulmonary Fibrosis (IPF) 963
PO 963
Adults. 963
Side Effects/Adverse Reactions 963
Frequent 963
Occasional 963
Precautions and Contraindications 963
Drug Interactions of Concern to Dentistry 963
Serious Reactions 963
Dental Considerations 963
General: 963
Consultations: 964
Teach Patient/Family to: 964
nipradilol 964
Category and Schedule 964
Drug Class: 964
Mechanism of Action 964
Uses 964
Pharmacokinetics 964
Indications and Dosages 964
► Hypertension, Essential 964
nisoldipine 965
Category and Schedule 965
Drug Class: 965
Mechanism of Action 965
Uses 966
Pharmacokinetics 966
Indications and Dosages 966
► Hypertension 966
PO 966
Adults. 966
Side Effects/Adverse Reactions 966
Frequent 966
Occasional 966
Rare 966
Precautions and Contraindications 966
Caution: 966
Serious Reactions 966
Dental Considerations 966
General: 966
Consultations: 966
nitazoxanide 967
Category and Schedule 967
Drug Class: 967
Mechanism of Action 967
Uses 967
Pharmacokinetics 967
Indications and Dosages 967
► Diarrhea 967
PO 967
Children 12 yr and older. 967
Children 4–11 yr. 967
Children 12–47 mo. 967
Side Effects/Adverse Reactions 967
Occasional 967
Rare 967
Precautions and Contraindications 967
Drug Interactions of Concern to Dentistry 967
Serious Reactions 967
Dental Considerations 967
General: 967
Consultations: 967
Teach Patient/Family to: 967
nitrofurantoin sodium 968
Category and Schedule 968
Drug Class: 968
Mechanism of Action 968
Uses 968
Pharmacokinetics 968
Indications and Dosages 968
► UTIs 968
PO (Furadantin, Macrodantin) 968
nitrofurazone 969
Category and Schedule 969
Drug Class: 969
Mechanism of Action 969
Uses 969
Pharmacokinetics 969
Indications and Dosages 969
► Burns, Catheter-Related UTI, Skin Grafts 969
Topical 969
Adults. 969
Side Effects/Adverse Reactions 969
Occasional 969
Precautions and Contraindications 969
Drug Interactions of Concern to Dentistry 969
Serious Reactions 969
Dental Considerations 969
General: 969
Consultations: 969
Teach Patient/Family to: 969
nitroglycerin 970
Category and Schedule 970
Drug Class: 970
Mechanism of Action 970
Uses 970
Pharmacokinetics 970
Indications and Dosages 970
► Acute Relief of Angina Pectoris, Acute Prophylaxis 970
Lingual Spray 970
nizatidine 972
Category and Schedule 972
Drug Class: 972
Mechanism of Action 972
Uses 972
Pharmacokinetics 972
Indications and Dosages 972
► Active Duodenal Ulcer 972
PO 972
Adults, Elderly. 972
► Prevention of Duodenal Ulcer Recurrence 973
norethindrone 973
Category and Schedule 973
Drug Class: 973
Mechanism of Action 973
Uses 974
Pharmacokinetics 974
Indications and Dosages 974
► Contraception 974
norfloxacin 975
Category and Schedule 975
Drug Class: 975
Mechanism of Action 975
Uses 975
Pharmacokinetics 975
Indications and Dosages 975
► UTIs 975
norgestrel 976
Category and Schedule 976
Drug Class: 976
Mechanism of Action 976
Uses 976
Pharmacokinetics 976
Indications and Dosages 976
► Contraception, Female 976
PO 976
Adults. 976
Side Effects/Adverse Reactions 976
Frequent 976
Occasional 977
Rare 977
Precautions and Contraindications 977
Caution: 977
Drug Interactions of Concern to Dentistry 977
Serious Reactions 977
Dental Considerations 977
General: 977
Teach Patient/Family to: 977
nortriptyline hydrochloride 977
Category and Schedule 977
Drug Class: 977
Mechanism of Action 977
Uses 977
Pharmacokinetics 977
Indications and Dosages 978
► Depression 978
nystatin 979
Category and Schedule 979
Drug Class: 979
Mechanism of Action 979
Uses 979
Pharmacokinetics 979
Indications and Dosages 979
Intestinal Infections 979
obeticholic acid 981
Category and Schedule 981
Drug Class: 981
Mechanism of Action 981
Uses 981
Pharmacokinetics 981
Indications and Dosages 981
► Primary Biliary Cholangitis 981
PO 981
Adults. 981
Side Effects/Adverse Reactions 981
Frequent 981
Occasional 981
Precautions and Contraindications 981
Drug Interactions of Concern to Dentistry 981
Serious Reactions 981
Dental Considerations 981
General: 981
Consultations: 982
Teach Patient/Family to: 982
octreotide acetate 982
Category and Schedule 982
Drug Class: 982
Mechanism of Action 982
Uses 982
Pharmacokinetics 982
Indications and Dosages 982
► Diarrhea 982
olanzapine 983
Category and Schedule 983
Drug Class: 983
Mechanism of Action 983
Uses 984
Pharmacokinetics 984
Indications and Dosages 984
► Schizophrenia 984
olaparib 985
Category and Schedule 985
Drug Class: 985
Mechanism of Action 986
Uses 986
Pharmacokinetics 986
Indications and Dosages 986
► Ovarian Cancer, Advanced 986
PO 986
Adults. 986
Side Effects/Adverse Reactions 986
Frequent 986
Occasional 986
Precautions and Contraindications 986
Drug Interactions of Concern to Dentistry 986
Serious Reactions 986
Dental Considerations 987
General: 987
Consultations: 987
Teach Patient/Family to: 987
olmesartan 987
Category and Schedule 987
Drug Class: 987
Mechanism of Action 987
Uses 987
Pharmacokinetics 987
Indications and Dosages 987
► Hypertension (with or without Other Antihypertensive Agents) 987
PO 987
Adults. 987
Elderly. 988
Side Effects/Adverse Reactions 988
Adults 988
Frequent 988
Occasional 988
Children 988
Precautions and Contraindications 988
Drug Interactions of Concern to Dentistry 988
Serious Reactions 988
Dental Considerations 988
General: 988
Consultations: 988
Teach Patient/Family to: 988
olmesartan medoxomil 988
Category and Schedule 988
Drug Class: 988
Mechanism of Action 988
Uses 989
Pharmacokinetics 989
Indications and Dosages 989
► Hypertension 989
PO 989
Adults, Elderly, Patients with mildly impaired hepatic or renal function. 989
Side Effects/Adverse Reactions 989
Occasional 989
Rare 989
Precautions and Contraindications 989
Caution: 989
Drug Interactions of Concern to Dentistry 989
Serious Reactions 989
Dental Considerations 989
General: 989
Consultations: 989
Teach Patient/Family to: 990
olodaterol 990
Category and Schedule 990
Drug Class: 990
Mechanism of Action 990
Uses 990
Pharmacokinetics 990
Indications and Dosages 990
Dosage and Routes: 990
► Chronic Obstructive Pulmonary Disease 990
Adults. 990
PO 990
Side Effects/Adverse Reactions 990
Frequent 990
Occasional 990
Precautions and Contraindications 990
Drug Interactions of Concern to Dentistry 991
Serious Reactions 991
Dental Considerations 991
General: 991
Consultations: 991
Teach Patient/Family to: 991
olopatadine 991
Category and Schedule 991
Drug Class: 991
Mechanism of Action 991
Uses 991
Pharmacokinetics 991
Indications and Dosages 991
► Allergic Conjunctivitis 991
Topical, Ophthalmic/Intranasal 991
Adult. 991
olsalazine sodium 992
Category and Schedule 992
Drug Class: 992
Mechanism of Action 992
Uses 992
Pharmacokinetics 992
Indications and Dosages 992
► Maintenance of Controlled Ulcerative Colitis 992
PO 992
Adults, Elderly. 992
Side Effects/Adverse Reactions 992
Frequent 992
Occasional 992
Precautions and Contraindications 992
Drug Interactions of Concern to Dentistry 992
Serious Reactions 992
Dental Considerations 992
General: 992
Consultations: 992
Teach Patient/Family to: 992
Occasional 993
Rare 993
Precautions and Contraindications 993
Caution: 993
Serious Reactions 993
Dental Considerations 993
General: 993
Consultations: 993
Teach Patient/Family to: 993
omalizumab 993
Category and Schedule 993
Drug Class: 993
Mechanism of Action 993
Uses 993
Pharmacokinetics 993
Indications and Dosages 993
► Moderate-to-Severe Persistent Asthma in Patients Who Are Reactive to a Perennial Allergen and Whose Asthma Symptoms Have Been Inadequately Controlled with Inhaled Corticosteroids 993
Subcutaneous 993
Adults, Elderly, Children 12 yr and older. 993
Side Effects/Adverse Reactions 994
Frequent 994
Occasional 994
Rare 994
Precautions and Contraindications 994
Caution: 994
Drug Interactions of Concern to Dentistry 994
Serious Reactions 994
Dental Considerations 994
General: 994
Consultations: 995
Teach Patient/Family to: 995
ombitasvir, paritaprevir, ritonavir, and dasabuvir 995
Category and Schedule 995
Drug Class: 995
Mechanism of Action 995
Uses 995
Pharmacokinetics 995
Indications and Dosages 996
► Chronic Hepatitis C: 996
PO 996
Adults. 996
Side Effects/Adverse Reactions 996
Frequent 996
Occasional 996
Precautions and Contraindications 996
Drug Interactions of Concern to Dentistry 996
Serious Reactions 997
Dental Considerations 997
General: 997
Consultations: 997
Teach Patient/Family to: 997
omega-3-carboxylic acids 997
Category and Schedule 997
Drug Class: 997
Mechanism of Action 997
Uses 997
Pharmacokinetics 997
Indications and Dosages 997
► Severe Hypertriglyceridemia (TGL ≥500 mg/dl) 997
PO 997
Adults. 997
omega-3 fatty acids 998
Category and Schedule 998
Drug Class: 998
Mechanism of Action 998
Uses 998
Pharmacokinetics 998
Indications and Dosages 998
► Hypertriglyceridemia, Severe (≥500 mg/dl), Adjunct to Diet 998
PO 998
Adults. 998
Side Effects/Adverse Reactions 998
Frequent 998
Occasional 998
Rare 998
Precautions and Contraindications 998
Drug Interactions of Concern to Dentistry 998
Serious Reactions 998
Dental Considerations 998
General: 998
Consultations: 998
Teach Patient/Family to: 998
Caution: 999
Drug Interactions of Concern to Dentistry 999
Serious Reactions 999
Dental Considerations 999
General: 999
Consultations: 999
Teach Patient/Family to: 999
omeprazole 999
Category and Schedule 999
Drug Class: 999
Mechanism of Action 999
Uses 999
Pharmacokinetics 1000
Indications and Dosages 1000
► Erosive Esophagitis, Poorly Responsive GERD, Active Duodenal Ulcer, Prevention and Treatment of NSAID-Induced Ulcers 1000
ondansetron, oral soluble film 1001
Category and Schedule 1001
Drug Class: 1001
Mechanism of Action 1001
Uses 1001
Pharmacokinetics 1001
Indications and Dosages 1001
► Prevention of Chemotherapy-Induced Nausea and Vomiting 1001
oprelvekin (interleukin-2, IL-2) 1002
Category and Schedule 1002
Drug Class: 1002
Mechanism of Action 1002
Uses 1002
Pharmacokinetics 1002
Indications and Dosages 1002
► Prevention of Thrombocytopenia 1002
Subcutaneous 1002
Adults. 1002
Children. 1002
Side Effects/Adverse Reactions 1002
Frequent 1002
Precautions and Contraindications 1002
Drug Interactions of Concern to Dentistry 1002
Serious Reactions 1002
Dental Considerations 1002
General: 1002
Teach Patient/Family: 1002
Dental Considerations 1003
General: 1003
Consultations: 1003
Teach Patient/Family to: 1003
orlistat 1003
Category and Schedule 1003
Drug Class: 1003
Mechanism of Action 1003
Uses 1003
Pharmacokinetics 1004
Indications and Dosages 1004
► Weight Reduction 1004
PO 1004
Adults, Elderly, Children 12–16 yr. 1004
Side Effects/Adverse Reactions 1004
Frequent 1004
Occasional 1004
Rare 1004
Precautions and Contraindications 1004
Caution: 1004
Drug Interactions of Concern to Dentistry 1004
Serious Reactions 1004
Dental Considerations 1004
General: 1004
Consultations: 1004
Teach Patient/Family to: 1004
orphenadrine 1004
Category and Schedule 1004
Drug Class: 1004
Mechanism of Action 1004
Uses 1005
Pharmacokinetics 1005
Indications and Dosages 1005
► Musculoskeletal Pain 1005
IM/IV 1005
oseltamivir 1006
Category and Schedule 1006
Drug Class: 1006
Mechanism of Action 1006
Uses 1006
Pharmacokinetics 1006
Indications and Dosages 1006
► Influenza 1006
ospemifene 1007
Category and Schedule 1007
Drug Class: 1007
Mechanism of Action 1007
Uses 1007
Pharmacokinetics 1007
Indications and Dosages 1007
► Adult Dyspareunia, Moderate to Severe 1007
PO 1007
Adults. 1007
Side Effects/Adverse Reactions 1007
Frequent 1007
Occasional 1007
Precautions and Contraindications 1007
Drug Interactions of Concern to Dentistry 1007
Serious Reactions 1007
Dental Considerations 1008
General: 1008
Teach Patient/Family to: 1008
oxacillin 1008
Category and Schedule 1008
Drug Class: 1008
Mechanism of Action 1008
Uses 1008
Pharmacokinetics 1008
Indications and Dosages 1008
► Upper Respiratory Tract, Skin, and Skin-Structure Infections 1008
oxaliplatin 1009
Category and Schedule 1009
Drug Class: 1009
Mechanism of Action 1009
Uses 1009
Pharmacokinetics 1009
Indications and Dosages 1009
► Metastatic Colon or Rectal Cancer in Patients Whose Disease Has Recurred or Progressed During or Within 6 Mo of Completing First-Line Therapy with Bolus 5-Fluorouracil (5-FU), Leucovorin, and Irinotecan 1009
oxandrolone 1011
Category and Schedule 1011
Drug Class: 1011
Mechanism of Action 1011
Uses 1011
Pharmacokinetics 1011
Indications and Dosages 1011
► Weight Gain 1011
Adults, Elderly. 1011
Children. 1011
Side Effects/Adverse Reactions 1011
Frequent 1011
Occasional 1011
Rare 1011
Precautions and Contraindications 1011
Caution: 1012
Drug Interactions of Concern to Dentistry 1012
Serious Reactions 1012
Dental Considerations 1012
General: 1012
Consultations: 1012
Teach Patient/Family to: 1012
oxaprozin 1012
Category and Schedule 1012
Drug Class: 1012
Mechanism of Action 1012
Uses 1012
Pharmacokinetics 1012
Indications and Dosages 1012
► Osteoarthritis 1012
PO 1012
Adults, Elderly. 1012
► Rheumatoid Arthritis 1013
PO 1013
Adults, Elderly. 1013
► Juvenile Rheumatoid Arthritis 1013
Children weighing more than 54 kg. 1013
Children weighing 32–54 kg. 1013
Children weighing 22–31 kg. 1013
► Dosage in Renal Impairment 1013
Side Effects/Adverse Reactions 1013
Occasional 1013
Rare 1013
Precautions and Contraindications 1013
Caution: 1013
Drug Interactions of Concern to Dentistry 1013
Serious Reactions 1013
Dental Considerations 1013
General: 1013
Consultations: 1013
Teach Patient/Family to: 1014
oxazepam 1014
Category and Schedule 1014
Drug Class: 1014
Mechanism of Action 1014
Uses 1014
Pharmacokinetics 1014
Indications and Dosages 1014
► Mild-to-Moderate Anxiety 1014
oxcarbazepine 1015
Category and Schedule 1015
Drug Class: 1015
Mechanism of Action 1015
Uses 1015
Pharmacokinetics 1015
Indications and Dosages 1015
► Adjunctive Treatment of Seizures 1015
PO 1015
Adults, Elderly. 1015
Children 4–16 yr. 1015
► Conversion to Monotherapy 1016
oxiconazole 1017
Category and Schedule 1017
Drug Class: 1017
Mechanism of Action 1017
Uses 1017
Pharmacokinetics 1017
Indications and Dosages 1017
► Tinea pedis 1017
oxidized cellulose 1018
Category and Schedule 1018
Drug Class: 1018
Mechanism of Action 1018
Uses 1018
Pharmacokinetics 1018
Indications and Dosages 1018
► Surgical Procedures to Assist in the Control of Capillary, Venous, and Small Arterial Hemorrhage When Ligation or Other Conventional Methods of Control Are Impractical or Ineffective 1018
Topical 1018
Adults. 1018
Side Effects/Adverse Reactions 1018
Frequency Not Defined 1018
Precautions and Contraindications 1018
Caution: 1018
Serious Reactions 1018
Dental Considerations 1018
General: 1018
oxybutynin 1019
Category and Schedule 1019
Drug Class: 1019
Mechanism of Action 1019
Uses 1019
Pharmacokinetics 1019
Indications and Dosages 1019
► Neurogenic Bladder 1019
PO 1019
oxycodone 1020
Category and Schedule 1020
Drug Class: 1020
Mechanism of Action 1020
Uses 1020
Pharmacokinetics 1020
Indications and Dosages 1021
► Analgesia 1021
PO (Controlled-Release) 1021
oxycodone + naltrexone 1022
Category and Schedule 1022
Drug Class: 1022
Mechanism of Action 1022
Uses 1022
Pharmacokinetics 1022
Indications and Dosages 1022
► Pain Management 1022
PO 1022
Adults. 1022
Side Effects/Adverse Reactions 1023
Frequent 1023
Occasional 1023
Precautions and Contraindications 1023
Drug Interactions of Concern to Dentistry 1024
Serious Reactions 1024
Dental Considerations 1024
General: 1024
Consultations: 1024
Teach Patient/Family to: 1024
oxymetazoline 1024
Category and Schedule 1024
Drug Class: 1024
Mechanism of Action 1025
Uses 1025
Pharmacokinetics 1025
Indications and Dosages 1025
► Rhinitis 1025
Intranasal 1025
oxymetholone 1025
Category and Schedule 1025
Drug Class: 1025
Mechanism of Action 1026
Uses 1026
Pharmacokinetics 1026
Indications and Dosages 1026
► Anemia, Chronic Renal Failure, Acquired Aplastic Anemia, Chemotherapy-Induced Myelosuppression, Fanconi’s Anemia, Red Cell Aplasia 1026
PO 1026
Adults, Elderly, Children. 1026
Side Effects/Adverse Reactions 1026
Frequent 1026
Occasional 1026
Rare 1026
Precautions and Contraindications 1026
Caution: 1026
Drug Interactions of Concern to Dentistry 1026
Serious Reactions 1026
Dental Considerations 1027
General: 1027
Consultations: 1027
Teach Patient/Family to: 1027
paclitaxel 1028
Category and Schedule 1028
Drug Class: 1028
Mechanism of Action 1028
Uses 1028
Pharmacokinetics 1028
Indications and Dosages 1028
► Ovarian Cancer 1028
paliperidone 1029
Category and Schedule 1029
Drug Class: 1029
Mechanism Of Action 1029
Uses 1029
Pharmacokinetics 1029
Indications and Dosages 1029
► Schizophrenia 1029
PO (Extended-Release) 1029
Adults. 1029
► Renal Impairment 1030
PO (Extended-Release) 1030
Side Effects/Adverse Reactions 1030
Frequent 1030
Occasional 1030
Rare 1030
Precautions and Contraindications 1030
Caution: 1030
Drug Interactions of Concern to Dentistry 1030
Serious Reactions 1030
Dental Considerations 1030
General: 1030
Consultations: 1031
Teach Patient/Family to: 1031
palonosetron hydrochloride 1031
Category and Schedule 1031
Drug Class: 1031
Mechanism of Action 1031
Uses 1031
Pharmacokinetics 1031
Indications and Dosages 1031
► Chemotherapy-Induced Nausea and Vomiting 1031
IV 1031
Adults, Elderly. 1031
Side Effects/Adverse Reactions 1031
Occasional 1031
Rare 1031
Precautions and Contraindications 1031
Drug Interactions of Concern to Dentistry 1032
Serious Reactions 1032
Dental Considerations 1032
General: 1032
Teach Patient/Family to: 1032
pamidronate disodium 1032
Category and Schedule 1032
Drug Class: 1032
Mechanism of Action 1032
Uses 1032
Pharmacokinetics 1032
Indications and Dosages 1032
► Hypercalcemia 1032
pancreatin/pancrelipase 1033
Category and Schedule 1033
Drug Class: 1033
Mechanism of Action 1033
Uses 1033
Pharmacokinetics 1034
Indications and Dosages 1034
► Pancreatic Insufficiency 1034
Adult. 1034
Children 7–12 yr. 1034
Children 1–6 yr. 1034
Side Effects/Adverse Reactions 1034
Frequent 1034
Occasional 1034
Rare 1034
Precautions and Contraindications 1034
Drug Interactions of Concern to Dentistry 1034
Serious Reactions 1034
Dental Considerations 1034
General: 1034
Consultations: 1034
Teach Patient/Family to: 1034
panitumumab 1034
Category and Schedule 1034
Drug Class: 1034
Mechanism of Action 1034
Uses 1034
Pharmacokinetics 1035
Indications and Dosages 1035
► EGFR-Positive Metastatic Colorectal Cancer 1035
IV Infusion 1035
Adults. 1035
► Dosing Adjustments 1035
Infusion Reactions 1035
► Dermatologic Toxicity 1035
Dermatologic toxicity (grade 3 or 4). 1035
Dermatologic toxicity (grade 2 or lower), and the patient is symptomatically improved after withholding no more than 2 doses of panitumumab. 1035
Side Effects/Adverse Reactions 1035
Frequent 1035
Occasional 1035
Rare 1035
Precautions and Contraindications 1035
Drug Interactions of Concern to Dentistry 1035
Serious Reactions 1035
Dental Considerations 1035
General: 1035
Consultations: 1035
Teach Patient/Family to: 1035
panobinostat 1036
Category and Schedule 1036
Drug Class: 1036
Mechanism of Action 1036
Uses 1036
Pharmacokinetics 1036
Indications and Dosages 1036
► Multiple Myeloma 1036
PO 1036
Adults. 1036
Side Effects/Adverse Reactions 1036
Frequent 1036
Occasional 1036
Precautions and Contraindications 1036
Drug Interactions of Concern to Dentistry 1037
Serious Reactions 1037
Dental Considerations 1037
General: 1037
Consultations: 1037
Teach Patient/Family to: 1037
pantoprazole 1038
Category and Schedule 1038
Drug Class: 1038
Mechanism of Action 1038
Uses 1038
Pharmacokinetics 1038
Indications and Dosages 1038
► Erosive Esophagitis 1038
papaverine hydrochloride 1039
Category and Schedule 1039
Drug Class: 1039
Mechanism of Action 1039
Uses 1039
Pharmacokinetics 1039
Indications and Dosages 1039
► Vascular Spasm 1039
IV/IM 1039
paregoric 1040
Category and Schedule 1040
Drug Class: 1040
Mechanism of Action 1040
Uses 1040
Pharmacokinetics 1040
Indications and Dosages 1040
► Antidiarrheal 1040
PO 1040
Adults, Elderly. 1040
Children. 1040
Side Effects/Adverse Reactions 1040
Frequent 1040
Occasional 1040
Rare 1040
Precautions and Contraindications 1041
Caution: 1041
Drug Interactions of Concern to Dentistry 1041
Serious Reactions 1041
Dental Considerations 1041
General: 1041
Teach Patient/Family to: 1041
pargyline 1041
Category and Schedule 1041
Drug Class: 1041
Mechanism of Action 1041
Uses 1041
Pharmacokinetics 1041
Indications and Dosages 1041
► Hypertension 1041
PO 1041
Adults. 1041
Side Effects/Adverse Reactions 1041
Frequent 1041
Occasional 1041
Rare 1041
Precautions and Contraindications 1042
Caution: 1042
Drug Interactions of Concern to Dentistry 1042
Serious Reactions 1042
Dental Considerations 1042
General: 1042
Consultations: 1042
Teach Patient/Family to: 1042
paromomycin 1042
Category and Schedule 1042
Drug Class: 1042
Mechanism of Action 1042
Uses 1042
Pharmacokinetics 1042
Indications and Dosages 1042
► Intestinal Amebiasis 1042
PO 1042
Adults, Elderly, Children. 1042
► Hepatic Coma 1043
PO 1043
Adults, Elderly. 1043
Side Effects/Adverse Reactions 1043
Occasional 1043
Rare 1043
Precautions and Contraindications 1043
Drug Interactions of Concern to Dentistry 1043
Serious Reactions 1043
Dental Considerations 1043
General: 1043
Consultations: 1043
Teach Patient/Family to: 1043
paroxetine hydrochloride 1043
Category and Schedule 1043
Drug Class: 1043
Mechanism of Action 1043
Uses 1043
Pharmacokinetics 1044
Indications and Dosages 1044
► Depression 1044
pazopanib 1045
Category and Schedule 1045
Drug Class: 1045
Mechanism of Action 1045
Uses 1045
Pharmacokinetics 1045
Indications and Dosages 1045
► Advanced Renal Cell Cancer 1045
PO 1045
Adults, Elderly. 1045
► Dosage Adjustment for Moderate Hepatic Impairment 1046
Side Effects/Adverse Reactions 1046
Frequent 1046
Occasional 1046
Precautions and Contraindications 1046
Drug Interactions of Concern to Dentistry 1046
Serious Reactions 1046
Dental Considerations 1046
General: 1046
Consultations: 1046
Teach Patient/Family to: 1046
pegfilgrastim 1047
Category and Schedule 1047
Drug Class: 1047
Mechanism of Action 1047
Uses 1047
Pharmacokinetics 1047
Indications and Dosages 1047
► Myelosuppression 1047
Subcutaneous 1047
Adults, Elderly. 1047
Side Effects/Adverse Reactions 1047
Frequent 1047
Precautions and Contraindications 1047
Drug Interactions of Concern to Dentistry 1047
Serious Reactions 1047
Dental Considerations 1047
General: 1047
Consultations: 1048
Teach Patient/Family to: 1048
peginterferon alfa-2a 1048
Category and Schedule 1048
Drug Class: 1048
Mechanism of Action 1048
Uses 1048
Pharmacokinetics 1048
Indications and Dosages 1048
► Hepatitis C 1048
Subcutaneous 1048
Adults 18 yr and older, Elderly. 1048
► Dosage in Renal Impairment 1048
► Dosage in Hepatic Impairment 1048
Side Effects/Adverse Reactions 1048
Frequent 1048
Occasional 1048
Precautions and Contraindications 1048
Caution: 1048
Drug Interactions of Concern to Dentistry 1049
Serious Reactions 1049
Dental Considerations 1049
General: 1049
Consultations: 1049
Teach Patient/Family to: 1049
peginterferon alfa-2b 1049
Category and Schedule 1049
Drug Class: 1049
Mechanism of Action 1049
Uses 1050
Pharmacokinetics 1050
Indications and Dosages 1050
► Chronic Hepatitis C, Monotherapy 1050
Subcutaneous 1050
Adults 18 yr and older, Elderly. 1050
► Chronic Hepatitis C 1050
Side Effects/Adverse Reactions 1050
Frequent 1050
Occasional 1050
Rare 1050
Precautions and Contraindications 1050
Caution: 1050
Drug Interactions of Concern to Dentistry 1050
Serious Reactions 1050
Dental Considerations 1051
General: 1051
Consultations: 1051
Teach Patient/Family to: 1051
pegvisomant 1051
Category and Schedule 1051
Drug Class: 1051
Mechanism of Action 1051
Uses 1051
Pharmacokinetics 1051
Indications and Dosages 1052
► Acromegaly 1052
Subcutaneous 1052
Adults, Elderly. 1052
Side Effects/Adverse Reactions 1052
Frequent 1052
Occasional 1052
Rare 1052
Precautions and Contraindications 1052
Drug Interactions of Concern to Dentistry 1052
Serious Reactions 1052
Dental Considerations 1052
General: 1052
Consultations: 1052
Teach Patient/Family to: 1052
penbutolol 1052
Category and Schedule 1052
Drug Class: 1052
Mechanism of Action 1052
Uses 1052
Pharmacokinetics 1053
Indications and Dosages 1053
► Hypertension 1053
PO 1053
Adults. 1053
Elderly. 1053
Side Effects/Adverse Reactions 1053
Frequent 1053
Occasional 1053
Rare 1053
Precautions and Contraindications 1053
Caution: 1053
Drug Interactions of Concern to Dentistry 1053
Serious Reactions 1053
Dental Considerations 1053
General: 1053
Consultations: 1054
Teach Patient/Family to: 1054
penciclovir 1054
Category and Schedule 1054
Drug Class: 1054
Mechanism of Action 1054
Uses 1054
Pharmacokinetics 1054
Indications and Dosages 1054
► Herpes Labialis (Cold Sores) 1054
Topical 1054
Adolescents, Adults. 1054
Side Effects/Adverse Reactions 1054
Frequent 1054
Occasional 1054
Rare 1055
Precautions and Contraindications 1055
Caution: 1055
Drug Interactions of Concern to Dentistry 1055
Serious Reactions 1055
Dental Considerations 1055
General: 1055
Teach Patient/Family to: 1055
penicillin G benzathine 1055
Category and Schedule 1055
Drug Class: 1055
Mechanism of Action 1055
Uses 1055
Pharmacokinetics 1055
Indications and Dosages 1056
► Group A Streptococcal Infections 1056
penicillin G potassium 1057
Category and Schedule 1057
Drug Class: 1057
Mechanism of Action 1057
Uses 1057
Pharmacokinetics 1057
Indications and Dosages 1057
► Sepsis, Meningitis, Pericarditis, Endocarditis, Pneumonia Caused by Susceptible Gram-Positive Organisms (Not Staphylococcus aureus) and Some Gram-Negative Organisms 1057
IV, IM 1057
Adults, Elderly. 1057
Children. 1057
► Dosage in Renal Impairment 1057
Side Effects/Adverse Reactions 1057
Occasional 1057
Rare 1057
Precautions and Contraindications 1057
Drug Interactions of Concern to Dentistry 1057
Serious Reactions 1057
Dental Considerations 1058
General: 1058
Consultations: 1058
Teach Patient/Family to: 1058
penicillin V potassium 1058
Category and Schedule 1058
Drug Class: 1058
Mechanism of Action 1058
Uses 1058
Pharmacokinetics 1058
Indications and Dosages 1058
► Mild-to-Moderate Respiratory Tract or Skin or Skin-Structure Infections, Otitis Media, Necrotizing Ulcerative Gingivitis 1058
pentamidine isethionate 1059
Category and Schedule 1059
Drug Class: 1059
Mechanism of Action 1059
Uses 1059
Pharmacokinetics 1059
Indications and Dosages 1059
► Pneumocystis carinii Pneumonia (PCP) 1059
IV, IM 1059
Adults, Elderly. 1059
Children. 1060
► Prevention of PCP 1060
Inhalation 1060
Adults, Elderly. 1060
Children 5 yr and older. 1060
Children younger than 5 yr. 1060
Side Effects/Adverse Reactions 1060
Frequent 1060
Occasional 1060
Rare 1060
Precautions and Contraindications 1060
Caution: 1060
Drug Interactions of Concern to Dentistry 1060
Serious Reactions 1060
Dental Considerations 1060
General: 1060
Consultations: 1060
Teach Patient/Family to: 1060
pentazocine hydrochloride; naloxone hydrochloride 1061
Category and Schedule 1061
Drug Class: 1061
Mechanism of Action 1061
Uses 1061
Pharmacokinetics 1061
Indications and Dosages 1061
► Pain, Moderate-to-Severe 1061
PO 1061
Adults, Elderly, Children 12 yr and older. 1061
Side Effects/Adverse Reactions 1061
Occasional 1061
Precautions and Contraindications 1061
Caution: 1061
Drug Interactions of Concern to Dentistry 1061
Serious Reactions 1062
Dental Considerations 1062
General: 1062
Teach Patient/Family: 1062
pentazocine 1062
Combination Products 1062
Category and Schedule 1062
Drug Class: 1062
Mechanism of Action 1062
Uses 1062
Pharmacokinetics 1062
Indications and Dosages 1062
► Analgesia 1062
PO (with Naloxone) 1062
Adults. 1062
Elderly. 1062
► Subcutaneous/IM/IV (without Naloxone) 1063
pentobarbital 1064
Category and Schedule 1064
Drug Class: 1064
Mechanism of Action 1064
Uses 1064
Pharmacokinetics 1064
Indications and Dosages 1064
► Preanesthetic 1064
pentosan polysulfate 1066
Category and Schedule 1066
Drug Class: 1066
Mechanism of Action 1066
Uses 1066
Pharmacokinetics 1066
Indications and Dosages 1066
► Interstitial Cystitis 1066
PO 1066
Adults, Elderly. 1066
Side Effects/Adverse Reactions 1066
Frequent 1066
Occasional 1066
Precautions and Contraindications 1066
Drug Interactions of Concern to Dentistry 1066
Serious Reactions 1066
Dental Considerations 1066
General: 1066
Consultations: 1067
Teach Patient/Family to: 1067
pentostatin 1067
Category and Schedule 1067
Drug Class: 1067
Mechanism of Action 1067
Uses 1067
Pharmacokinetics 1067
Indications and Dosages 1067
► Hairy Cell Leukemia 1067
IV 1067
Adults, Elderly. 1067
► Dosage in Renal Impairment 1067
Side Effects/Adverse Reactions 1067
Frequent 1067
Occasional 1067
Precautions and Contraindications 1067
Serious Reactions 1067
Dental Considerations 1068
pentoxifylline 1068
Category and Schedule 1068
Drug Class: 1068
Mechanism of Action 1068
Uses 1068
Pharmacokinetics 1068
Indications and Dosages 1068
► Intermittent Claudication 1068
PO 1068
Adults, Elderly. 1068
Side Effects/Adverse Reactions 1068
Occasional 1068
Rare 1068
Precautions and Contraindications 1068
Caution: 1068
Drug Interactions of Concern to Dentistry 1068
Serious Reactions 1068
Dental Considerations 1069
General: 1069
Consultations: 1069
Teach Patient/Family to: 1069
perindopril 1069
Category and Schedule 1069
Drug Class: 1069
Mechanism of Action 1069
Uses 1069
Pharmacokinetics 1069
Indications and Dosages 1069
► Hypertension 1069
PO 1069
Adults, Elderly. 1069
Side Effects/Adverse Reactions 1070
Occasional 1070
Precautions and Contraindications 1070
Caution: 1070
Drug Interactions of Concern to Dentistry 1070
Serious Reactions 1070
Dental Considerations 1070
General: 1070
Consultations: 1070
Teach Patient/Family to: 1070
perindopril arginine + amlodipine 1071
Category and Schedule 1071
Drug Class: 1071
Mechanism of Action 1071
Uses 1071
Pharmacokinetics 1071
Indications and Dosages 1071
► Hypertension 1071
PO 1071
Adults. 1071
Side Effects/Adverse Reactions 1071
Frequent 1071
Occasional 1071
Precautions and Contraindications 1072
Drug Interactions of Concern to Dentistry 1072
Serious Reactions 1072
Dental Considerations 1072
General: 1072
Consultations: 1072
Teach Patient/Family to: 1072
perphenazine 1072
Category and Schedule 1072
Drug Class: 1072
Mechanism of Action 1073
Uses 1073
Pharmacokinetics 1073
Indications and Dosages 1073
► Severe Schizophrenia 1073
phenazopyridine hydrochloride 1074
Category and Schedule 1074
Drug Class: 1074
Mechanism of Action 1074
Uses 1074
Pharmacokinetics 1075
Indications and Dosages 1075
► Urinary Analgesic 1075
PO 1075
Adults. 1075
Children 6 yr and older. 1075
► Dosage in Renal Impairment 1075
Side Effects/Adverse Reactions 1075
Occasional 1075
Precautions and Contraindications 1075
Caution: 1075
Drug Interactions of Concern to Dentistry 1075
Serious Reactions 1075
Dental Considerations 1075
General: 1075
phendimetrazine 1075
Category and Schedule 1075
Drug Class: 1075
Mechanism of Action 1075
Uses 1075
Pharmacokinetics 1076
Indications and Dosages 1076
► Obesity 1076
PO 1076
Adults, Elderly. 1076
Side Effects/Adverse Reactions 1076
Occasional 1076
Precautions and Contraindications 1076
Caution: 1076
Drug Interactions of Concern to Dentistry 1076
Serious Reactions 1076
Dental Considerations 1076
General: 1076
Consultations: 1076
Teach Patient/Family to: 1076
phenelzine sulfate 1077
Category and Schedule 1077
Drug Class: 1077
Mechanism of Action 1077
Uses 1077
Pharmacokinetics 1077
Indications and Dosages 1077
► Depression Refractory to Other Antidepressants or Electroconvulsive Therapy 1077
PO 1077
Adults. 1077
Elderly. 1077
Side Effects/Adverse Reactions 1077
Frequent 1077
Occasional 1077
Rare 1077
Precautions and Contraindications 1077
Caution: 1077
Drug Interactions of Concern to Dentistry 1077
Serious Reactions 1078
Dental Considerations 1078
General: 1078
Consultations: 1078
Teach Patient/Family to: 1078
phenobarbital 1078
Category and Schedule 1078
Drug Class: 1078
Mechanism of Action 1078
Uses 1078
Pharmacokinetics 1079
Indications and Dosages 1079
► Status Epilepticus 1079
IV 1079
Adults, Elderly, Children, Neonates. 1079
► Seizure Control 1079
PO, IV 1079
Adults, Elderly, Children older than 12 yr. 1079
Children 6–12 yr. 1079
Children 1–5 yr. 1079
Children younger than 1 yr. 1079
Neonates. 1079
► Sedation 1079
PO, IM 1079
phenoxybenzamine 1080
Category and Schedule 1080
Drug Class: 1080
Mechanism of Action 1080
Uses 1080
Pharmacokinetics 1080
Indications and Dosages 1080
► Pheochromocytoma 1080
PO 1080
Adults. 1080
Children. 1080
Side Effects/Adverse Reactions 1081
Frequent 1081
Occasional 1081
Rare 1081
Precautions and Contraindications 1081
Drug Interactions of Concern to Dentistry 1081
Serious Reactions 1081
Dental Considerations 1081
General: 1081
Consultations: 1081
Teach Patient/Family to: 1081
phentermine 1081
Category and Schedule 1081
Drug Class: 1081
Mechanism of Action 1081
Uses 1082
Pharmacokinetics 1082
Indications and Dosages 1082
► Obesity 1082
PO 1082
Adults, Children older than 16 yr. 1082
Side Effects/Adverse Reactions 1082
Occasional 1082
Precautions and Contraindications 1082
Caution: 1082
Drug Interactions of Concern to Dentistry 1082
Serious Reactions 1082
Dental Considerations 1082
General: 1082
Consultations: 1082
Teach Patient/Family to: 1082
phentolamine 1083
Category and Schedule 1083
Drug Class: 1083
Mechanism of Action 1083
Uses 1083
Pharmacokinetics 1083
Indications and Dosages 1083
► Extravasation of Norepinephrine 1083
Subcutaneous 1083
phenylephrine hydrochloride 1085
Category and Schedule 1085
Drug Class: 1085
Mechanism of Action 1085
Uses 1085
Pharmacokinetics 1085
Indications and Dosages 1085
► Nasal Decongestant 1085
Nasal Spray, Nasal Solution 1085
phenylephrine hydrochloride; sulfacetamide sodium 1086
Category and Schedule 1086
Drug Class: 1086
Mechanism of Action 1086
Uses 1086
phenytoin 1087
Category and Schedule 1087
Drug Class: 1087
Mechanism of Action 1087
Uses 1087
Pharmacokinetics 1087
Indications and Dosages 1087
► Topical Application to Conjunctiva That Relieves Congestion, Itching, Minor Irritation; Whitens Sclera of Eye 1087
Ophthalmic 1087
Adults, Elderly, Children 12 yr and older. 1087
Side Effects/Adverse Reactions 1087
Occasional 1087
Precautions and Contraindications 1087
Drug Interactions of Concern to Dentistry 1087
Serious Reactions 1087
Dental Considerations 1087
General: 1087
Teach Patient/Family: 1087
Indications and Dosages 1088
physostigmine 1090
Category and Schedule 1090
Drug Class: 1090
Mechanism of Action 1090
Uses 1090
Indications and Dosages 1090
► To Reverse CNS Effects of Anticholinergic Drugs and Tricyclic Antidepressants 1090
IV, IM 1090
Adults, Elderly. 1090
Children. 1090
Side Effects/Adverse Reactions 1090
Expected 1090
Occasional 1090
Rare 1090
Precautions and Contraindications 1090
Drug Interactions of Concern to Dentistry 1090
Serious Reactions 1090
Dental Considerations 1091
General: 1091
Teach Patient/Family to: 1091
phytonadione 1091
Category and Schedule 1091
Drug Class: 1091
Mechanism of Action 1091
Uses 1091
Pharmacokinetics 1091
Indications and Dosages 1091
► Hypoprothrombinemia Caused by Vitamin K Malabsorption 1091
PO/IM 1091
pilocarpine hydrochloride 1092
Category and Schedule 1092
Drug Class: 1092
Mechanism of Action 1092
Uses 1092
Pharmacokinetics 1092
Indications and Dosages 1092
► Dry Mouth Associated with Radiation Treatment for Head and Neck Cancer 1092
pimecrolimus 1093
Category and Schedule 1093
Drug Class: 1093
Mechanism of Action 1093
Uses 1093
pimozide 1094
Category and Schedule 1094
Drug Class: 1094
Mechanism of Action 1094
Uses 1094
Pharmacokinetics 1094
Indications and Dosages 1094
► Atopic Dermatitis (Eczema) 1094
Topical 1094
Adults, Elderly, Children 2–17 yr. 1094
► Tourette’s Disorder 1094
PO 1094
Adults, Elderly. 1094
Children older than 12 yr. 1094
Side Effects/Adverse Reactions 1094
Rare 1094
Precautions and Contraindications 1094
Caution: 1094
Drug Interactions of Concern to Dentistry 1094
Serious Reactions 1094
Dental Considerations 1094
General: 1094
Occasional 1094
Rare 1095
Precautions and Contraindications 1095
Caution: 1095
Drug Interactions of Concern to Dentistry 1095
Serious Reactions 1095
Dental Considerations 1095
General: 1095
Consultations: 1096
Teach Patient/Family to: 1096
pindolol 1096
Category and Schedule 1096
Drug Class: 1096
Mechanism of Action 1096
Uses 1096
Pharmacokinetics 1096
Indications and Dosages 1096
► Mild-to-Moderate Hypertension 1096
pioglitazone 1098
Category and Schedule 1098
Drug Class: 1098
Mechanism of Action 1098
Uses 1098
Pharmacokinetics 1098
Indications and Dosages 1098
► Diabetes Mellitus, Combination Therapy 1098
PO 1098
Adult, Elderly. 1098
Side Effects/Adverse Reactions 1098
Frequent 1098
Occasional 1098
Precautions and Contraindications 1098
Caution: 1098
Drug Interactions of Concern to Dentistry 1098
Serious Reactions 1098
Dental Considerations 1098
General: 1098
Consultations: 1099
Teach Patient/Family to: 1099
pirbuterol 1099
Category and Schedule 1099
Drug Class: 1099
Mechanism of Action 1099
Uses 1099
Pharmacokinetics 1099
Indications and Dosages 1099
► Prevention of Bronchospasm 1099
pirfenidone 1100
Category and Schedule 1100
Drug Class: 1100
Mechanism of Action 1100
Uses 1100
Pharmacokinetics 1100
Indications and Dosages 1100
► Idiopathic pulmonary fibrosis 1100
PO 1100
Adults. 1100
Side Effects/Adverse Reactions 1101
Frequent 1101
Occasional 1101
Precautions and Contraindications 1101
Drug Interactions of Concern to Dentistry 1101
Serious Reactions 1101
Dental Considerations 1101
General: 1101
Consultations: 1101
Teach Patient/Family to: 1101
piroxicam 1102
Category and Schedule 1102
Drug Class: 1102
Mechanism of Action 1102
Uses 1102
Pharmacokinetics 1102
Indications and Dosages 1102
► Acute or Chronic Rheumatoid Arthritis and Osteoarthritis 1102
PO 1102
Adults, Elderly. 1102
Children. 1102
Side Effects/Adverse Reactions 1102
Frequent 1102
Occasional 1102
Rare 1102
Precautions and Contraindications 1102
Caution: 1102
Drug Interactions of Concern to Dentistry 1102
Serious Reactions 1102
Dental Considerations 1103
General: 1103
Consultations: 1103
Teach Patient/Family to: 1103
pitavastatin 1103
Category and Schedule 1103
Drug Class: 1103
Mechanism of Action 1103
Uses 1103
Pharmacokinetics 1103
Indications and Dosages 1104
► Hypercholesterolemia, Mixed Dyslipidemia 1104
PO 1104
Adults. 1104
► Dosage in Renal Impairment 1104
Mild to moderate impairment (CrCl 30 to less than 60 ml/min or ESRD on hemodialysis). 1104
Moderate to severe impairment (CrCl less than 30 ml/min and not on hemodialysis). 1104
Side Effects/Adverse Reactions 1104
Occasional 1104
Rare 1104
Precautions and Contraindications 1104
Caution: 1104
Drug Interactions of Concern to Dentistry 1104
Serious Reactions 1104
Dental Considerations 1104
General: 1104
Consultations: 1104
Teach Patient/Family to: 1105
podofilox 1105
Category and Schedule 1105
Drug Class: 1105
Mechanism of Action 1105
Uses 1105
Pharmacokinetics 1105
Indications and Dosages 1105
► Anogenital Warts 1105
podophyllum resin 1106
Category and Schedule 1106
Drug Class: 1106
Mechanism of Action 1106
Uses 1106
Pharmacokinetics 1106
Indications and Dosages 1106
► Genital Warts (Condylomata Acuminate) 1106
Topical 1106
Adults, Elderly, Children. 1106
Side Effects/Adverse Reactions 1106
Occasional 1106
Precautions and Contraindications 1106
Drug Interactions of Concern to Dentistry 1106
Serious Reactions 1106
Dental Considerations 1106
General: 1106
Consultations: 1107
Teach Patient/Family to: 1107
polymyxin B 1107
Category and Schedule 1107
Drug Class: 1107
Mechanism of Action 1107
Uses 1107
Pharmacokinetics 1107
Indications and Dosages 1107
► Mild-to-Moderate Infections 1107
IV 1107
polymyxin B sulfate; trimethoprim sulfate 1108
Category and Schedule 1108
Drug Class: 1108
Mechanism of Action 1108
Uses 1108
Pharmacokinetics 1108
Indications and Dosages 1108
► Treatment of Surface Ocular Bacterial Conjunctivitis and Blepharoconjunctivitis 1108
Ophthalmic 1108
Adults, Elderly, Children. 1108
Side Effects/Adverse Reactions 1108
Occasional 1108
Precautions and Contraindications 1108
Drug Interactions of Concern to Dentistry 1108
Serious Reactions 1108
Dental Considerations 1108
General: 1108
pomalidomide 1109
Category and Schedule 1109
Drug Class: 1109
Mechanism of Action 1109
Uses 1109
Pharmacokinetics 1109
Indications and Dosages 1109
► Multiple Myeloma, Relapsed/Refractory 1109
PO 1109
Adults. 1109
Side Effects/Adverse Reactions 1109
Frequent 1109
Occasional 1109
Precautions and Contraindications 1109
Drug Interactions of Concern to Dentistry 1110
Serious Reactions 1110
Dental Considerations 1110
General: 1110
Consultations: 1110
Teach Patient/Family to: 1110
posaconazole 1110
Category and Schedule 1110
Drug Class: 1110
Mechanism of Action 1110
Uses 1110
Pharmacokinetics 1111
Indications and Dosages 1111
► Prophylaxis of Invasive Fungal Infections 1111
potassium chloride 1112
Category and Schedule 1112
Drug Class: 1112
Mechanism of Action 1112
Uses 1112
Pharmacokinetics 1112
Indications and Dosages 1113
► Prevention of Hypokalemia (on Diuretic Therapy) 1113
potassium acetate/potassium bicarbonate-citrate/potassium chloride/potassium gluconate 1114
Category and Schedule 1114
Drug Class: 1114
Mechanism of Action 1114
Uses 1114
Pharmacokinetics 1114
Indications and Dosages 1114
► Prevention of Hypokalemia (in Patients on Diuretic Therapy) 1114
povidone iodine 1115
Category and Schedule 1115
Drug Class: 1115
Mechanism of Action 1115
Uses 1115
Indications and Dosages 1115
Topical 1115
Adults, Children. 1115
Side Effects/Adverse Reactions 1115
Frequent 1115
Precautions and Contraindications 1115
Caution: 1115
Drug Interactions of Concern to Dentistry 1115
Serious Reactions 1115
Dental Considerations 1115
General: 1115
Teach Patient/Family to: 1115
pramipexole 1116
Category and Schedule 1116
Drug Class: 1116
Mechanism of Action 1116
Uses 1116
Pharmacokinetics 1116
Indications and Dosages 1116
► Parkinson’s Disease 1116
PO 1116
Adults, Elderly. 1116
► Dosage in Renal Impairment 1116
Side Effects/Adverse Reactions 1116
Frequent 1116
Occasional 1116
Rare 1116
Precautions and Contraindications 1116
Caution: 1116
Drug Interactions of Concern to Dentistry 1117
Serious Reactions 1117
Dental Considerations 1117
General: 1117
Consultations: 1117
Teach Patient/Family to: 1117
prasugrel 1117
Category and Schedule 1117
Drug Class: 1117
Mechanisn of Action 1117
Uses 1117
Pharmacokinetics 1117
Indications and Dosages 1118
► Antiplatelet Therapy 1118
PO 1118
Adult, Elderly (under the age of 75). 1118
Side Effects/Adverse Reactions 1118
Frequent 1118
Occasional 1118
Rare 1118
Precautions and Contraindications 1118
Drug Interactions of Concern to Dentistry 1118
Serious Reactions 1118
Dental Considerations 1118
General: 1118
Consultations: 1118
Teach Patient/Family to: 1118
pravastatin 1119
Category and Schedule 1119
Drug Class: 1119
Mechanism of Action 1119
Uses 1119
Pharmacokinetics 1119
Indications and Dosages 1119
► Hyperlipidemia, Primary and Secondary Prevention of Cardiovascular Events in Patients with Elevated Cholesterol Levels 1119
PO 1119
Adults, Elderly. 1119
Children 14–18 yr. 1119
Children 8–13 yr. 1119
► Dosage in Hepatic and Renal Impairment 1119
Side Effects/Adverse Reactions 1119
Occasional 1119
Rare 1119
Precautions and Contraindications 1119
Caution: 1119
Drug Interactions of Concern to Dentistry 1119
prazosin hydrochloride 1120
Category and Schedule 1120
Drug Class: 1120
Mechanism of Action 1120
Uses 1120
Pharmacokinetics 1120
Indications and Dosages 1120
► Mild-to-Moderate Hypertension 1120
PO 1120
Adults, Elderly. 1120
Children. 1120
Side Effects/Adverse Reactions 1120
Frequent 1120
Occasional 1120
Rare 1120
Precautions and Contraindications 1120
Caution: 1120
Drug Interactions of Concern to Dentistry 1120
Serious Reactions 1120
Dental Considerations 1120
General: 1120
Dental Considerations 1121
General: 1121
Consultations: 1121
Teach Patient/Family to: 1121
prednisolone 1121
Category and Schedule 1121
Drug Class: 1121
Mechanism of Action 1121
Uses 1121
Pharmacokinetics 1121
Indications and Dosages 1122
► Substitution Therapy for Deficiency States: Acute or Chronic Adrenal Insufficiency, Congenital Adrenal Hyperplasia, and Adrenal Insufficiency Secondary to Pituitary Insufficiency; Nonendocrine Disorders: Arthritis; Rheumatic Carditis; Allergic, Collagen, Intestinal Tract, Liver, Ocular, Renal, Skin Diseases; Bronchial Asthma; Cerebral Edema; Malignancies 1122
PO 1122
prednisolone acetate 1123
Category and Schedule 1123
Drug Class: 1123
Mechanism of Action 1123
Uses 1123
Pharmacokinetics 1123
Indications and Dosages 1123
► Conjunctivitis 1123
Ophthalmic 1123
Adults, Elderly, Children. 1123
Side Effects/Adverse Reactions 1124
Occasional 1124
Precautions and Contraindications 1124
Caution: 1124
Drug Interactions of Concern to Dentistry 1124
Serious Reactions 1124
Dental Considerations 1124
General: 1124
Consultations: 1124
Teach Patient/Family to: 1125
prednisolone acetate; sulfacetamide sodium 1125
Category and Schedule 1125
Drug Class: 1125
Mechanism of Action 1125
Uses 1125
Pharmacokinetics 1125
Indications and Dosages 1125
► Steroid-Responsive Inflammatory Ocular Conditions for Which a Corticosteroid is Indicated and Where Superficial Bacterial Ocular Infection or a Risk of Bacterial Ocular Infection Exists 1125
Ophthalmic Ointment 1125
prednisolone sodium phosphate 1127
Category and Schedule 1127
Drug Class: 1127
Mechanism of Action 1127
Uses 1127
Pharmacokinetics 1127
Indications and Dosages 1127
► Asthma 1127
prednisone 1129
Category and Schedule 1129
Drug Class: 1129
Mechanism of Action 1129
Uses 1129
Pharmacokinetics 1129
Indications and Dosages 1129
► Substitution Therapy in Deficiency States: Acute or Chronic Adrenal Insufficiency, Congenital Adrenal Hyperplasia, and Adrenal Insufficiency Secondary to Pituitary Insufficiency; Nonendocrine Disorders: Arthritis; Rheumatic Carditis; Allergic, Collagen, Intestinal Tract, Liver, Ocular, Renal, Skin Diseases; Bronchial Asthma; Cerebral Edema; Malignancies 1129
PO 1129
Adults, Elderly. 1129
Children. 1129
Side Effects/Adverse Reactions 1129
Frequent 1129
Occasional 1130
Rare 1130
Precautions and Contraindications 1130
Caution: 1130
Drug Interactions of Concern to Dentistry 1130
Serious Reactions 1130
Dental Considerations 1130
General: 1130
Consultations: 1130
Teach Patient/Family to: 1131
pregabalin 1131
Category and Schedule 1131
Drug Class: 1131
Mechanism of Action 1131
Uses 1131
Pharmacokinetics 1131
Indications and Dosages 1131
► Partial-Onset Seizures 1131
prilocaine hydrochloride (local) 1132
Category and Schedule 1132
Drug Class: 1132
Mechanism of Action 1132
Uses 1132
Pharmacokinetics 1132
Indications and Dosages 1132
► Dental Injection: Infiltration or Conduction Block 1132
primaquine 1134
Category and Schedule 1134
Drug Class: 1134
Mechanism of Action 1134
Uses 1134
Pharmacokinetics 1134
Indications and Dosages 1134
► Treatment of Malaria 1134
primidone 1135
Category and Schedule 1135
Drug Class: 1135
Mechanism of Action 1135
Uses 1135
Pharmacokinetics 1135
Indications and Dosages 1135
► Seizure Control 1135
PO 1135
Adults, Elderly, Children 8 yr and older. 1135
Children younger than 8 yr. 1135
Neonates. 1135
Side Effects/Adverse Reactions 1136
Frequent 1136
Occasional 1136
Rare 1136
Precautions and Contraindications 1136
Caution: 1136
Drug Interactions of Concern to Dentistry 1136
Serious Reactions 1136
Dental Considerations 1136
General: 1136
Consultations: 1136
Teach Patient/Family to: 1136
probenecid 1137
Category and Schedule 1137
Drug Class: 1137
Mechanism of Action 1137
Uses 1137
Pharmacokinetics 1137
Indications and Dosages 1137
► Gout 1137
procaine 1138
Category and Schedule 1138
Drug Class: 1138
Mechanism of Action 1138
Uses 1138
Pharmacokinetics 1138
Indications and Dosages 1138
► Spinal Anesthesia 1138
Intrathecal 1138
procarbazine hydrochloride 1140
Category and Schedule 1140
Drug Class: 1140
Mechanism of Action 1140
Uses 1140
Pharmacokinetics 1140
Indications and Dosages 1140
► Advanced Hodgkin’s Disease 1140
PO 1140
Adults, Elderly. 1140
Children. 1140
Side Effects/Adverse Reactions 1140
Frequent 1140
Occasional 1140
Rare 1140
Precautions and Contraindications 1140
Caution: 1140
Drug Interactions of Concern to Dentistry 1140
Serious Reactions 1141
Dental Considerations 1141
General: 1141
Consultations: 1141
Teach Patient/Family to: 1141
prochlorperazine 1141
Category and Schedule 1141
Drug Class: 1141
Mechanism of Action 1141
Pharmacokinetics 1142
Indications and Dosages 1142
► Nausea and Vomiting 1142
procyclidine 1143
Category and Schedule 1143
Drug Class: 1143
Mechanism of Action 1144
Uses 1144
Pharmacokinetics 1144
Indications and Dosages 1144
► Drug-Induced Extrapyramidal Reactions 1144
progesterone 1145
Category and Schedule 1145
Drug Class: 1145
Mechanism of Action 1145
Uses 1145
Pharmacokinetics 1145
Indications and Dosages 1145
► Amenorrhea 1145
promethazine hydrochloride 1146
Category and Schedule 1146
Drug Class: 1146
Mechanism of Action 1146
Uses 1147
Pharmacokinetics 1147
Indications and Dosages 1147
► Allergic Symptoms 1147
propafenone hydrochloride 1148
Category and Schedule 1148
Drug Class: 1148
Mechanism of Action 1148
Uses 1148
Pharmacokinetics 1148
Indications and Dosages 1149
► Documented, Life-Threatening Ventricular Arrhythmias, such as Sustained Ventricular Tachycardia 1149
PO (Prompt-Release) 1149
propantheline 1150
Category and Schedule 1150
Drug Class: 1150
Mechanism of Action 1150
Uses 1150
Pharmacokinetics 1150
Indications and Dosages 1150
► Peptic Ulcer 1150
PO 1150
Adults, Elderly. 1150
Children. 1150
Side Effects/Adverse Reactions 1150
Frequent 1150
Occasional 1150
Rare 1150
Precautions and Contraindications 1150
Caution: 1150
Drug Interactions of Concern to Dentistry 1150
Serious Reactions 1151
Dental Considerations 1151
General: 1151
Consultations: 1151
Teach Patient/Family to: 1151
propofol 1151
Category and Schedule 1151
Drug Class: 1151
Mechanism of Action 1151
Uses 1151
Pharmacokinetics 1151
Indications and Dosages 1151
► Intensive Care Unit Sedation 1151
IV 1151
Adults, Elderly. 1151
► Anesthesia 1152
IV 1152
Adults, American Society of Anesthesiologists (ASA) I and II patients. 1152
Elderly, Debilitated, Hypovolemic, ASA III or IV patients. 1152
Children 3 yr and older, ASA I or II patients. 1152
Children 2 mo–16 yr. 1152
Side Effects/Adverse Reactions 1152
Frequent 1152
Occasional 1152
Rare 1152
Precautions and Contraindications 1152
Caution: 1152
Drug Interactions of Concern to Dentistry 1152
Serious Reactions 1152
Dental Considerations 1152
General: 1152
propranolol hydrochloride 1153
Category and Schedule 1153
Drug Class: 1153
Mechanism of Action 1153
Uses 1153
Pharmacokinetics 1153
Indications and Dosages 1153
► Hypertension 1153
PO 1153
Adults, Elderly. 1153
Children. 1153
► Angina 1154
propylthiouracil 1156
Category and Schedule 1156
Drug Class: 1156
Mechanism of Action 1156
Uses 1156
Pharmacokinetics 1156
Indications and Dosages 1156
► Hyperthyroidism 1156
PO 1156
Adults, Elderly. 1156
Children. 1156
Neonates. 1156
Side Effects/Adverse Reactions 1156
Frequent 1156
Occasional 1156
Rare 1156
Precautions and Contraindications 1156
Caution: 1156
Drug Interactions of Concern to Dentistry 1156
Serious Reactions 1156
Dental Considerations 1156
General: 1156
Consultations: 1157
protein C, human 1157
Category and Schedule 1157
Drug Class: 1157
Mechanism of Action 1157
Uses 1157
Pharmacokinetics 1157
Indications and Dosages 1157
► Severe Congenital Protein C Deficiency for the Prevention and Treatment of Venous Thrombosis and Purpura Fulminans, Replacement Therapy for Pediatric and Adult Patients 1157
Injection, Powder for Reconstitution 1157
Adults. 1157
Side Effects/Adverse Reactions 1157
Occasional 1157
Precautions and Contraindications 1157
Caution: 1157
Drug Interactions of Concern to Dentistry 1157
Serious Reactions 1158
Dental Considerations 1158
General: 1158
Consultations: 1158
Teach Patient/Family to: 1158
protriptyline 1158
Category and Schedule 1158
Drug Class: 1158
Mechanism of Action 1158
Uses 1158
Pharmacokinetics 1158
Indications and Dosages 1158
► Depression 1158
PO 1158
Adults. 1158
Elderly. 1158
Side Effects/Adverse Reactions 1158
Frequent 1158
Occasional 1158
Rare 1158
Precautions and Contraindications 1159
Caution: 1159
Drug Interactions of Concern to Dentistry 1159
Serious Reactions 1159
Dental Considerations 1159
General: 1159
Consultations: 1159
Teach Patient/Family to: 1159
pseudoephedrine 1160
Category and Schedule 1160
Drug Class: 1160
Mechanism of Action 1160
Uses 1160
Pharmacokinetics 1160
Indications and Dosages 1160
► Decongestant 1160
PO 1160
pyrazinamide 1161
Category and Schedule 1161
Drug Class: 1161
Mechanism of Action 1161
Uses 1161
Pharmacokinetics 1161
Indications and Dosages 1161
► TB (in Combination with Other Antituberculars) 1161
PO 1161
Adults. 1161
Children. 1161
Side Effects/Adverse Reactions 1161
Frequent 1161
Rare 1161
Precautions and Contraindications 1162
Caution: 1162
Drug Interactions of Concern to Dentistry 1162
Serious Reactions 1162
Dental Considerations 1162
General: 1162
Consultations: 1162
Teach Patient/Family to: 1162
pyridostigmine bromide 1162
Category and Schedule 1162
Drug Class: 1162
Mechanism of Action 1162
Uses 1162
Pharmacokinetics 1162
Indications and Dosages 1162
► Myasthenia Gravis 1162
PO 1162
Adults, Elderly. 1162
PO (Extended-Release) 1162
pyridoxine hydrochloride (vitamin B6) 1164
Category and Schedule 1164
Drug Class: 1164
Mechanism of Action 1164
Uses 1164
Pharmacokinetics 1164
Indications and Dosages 1164
► Pyridoxine Deficiency 1164
PO 1164
pyrimethamine 1165
Category and Schedule 1165
Drug Class: 1165
Mechanism of Action 1165
Uses 1165
Pharmacokinetics 1165
Indications and Dosages 1165
► Toxoplasmosis 1165
quazepam 1167
Category and Schedule 1167
Drug Class: 1167
Mechanism of Action 1167
Uses 1167
Pharmacokinetics 1167
Indications and Dosages 1167
► Insomnia 1167
PO 1167
Adults (older than 18 yr). 1167
Elderly, debilitated, liver disease. 1167
Side Effects/Adverse Reactions 1167
Frequent 1167
Occasional 1167
Rare 1167
Precautions and Contraindications 1167
Caution: 1167
Drug Interactions of Concern to Dentistry 1167
Serious Reactions 1167
Dental Considerations 1168
General: 1168
Consultations: 1168
Teach Patient/Family to: 1168
quetiapine 1168
Category and Schedule 1168
Drug Class: 1168
Mechanism of Action 1168
Uses 1168
Pharmacokinetics 1168
Indications and Dosages 1168
► To Manage Manifestations of Psychotic Disorders, Bipolar Disorder 1168
PO 1168
Adults, Elderly. 1168
► Dosage in Hepatic Impairment, Elderly or Debilitated Patients, and Those Predisposed to Hypotensive Reactions 1168
Side Effects/Adverse Reactions 1169
Frequent 1169
Occasional 1169
Rare 1169
Precautions and Contraindications 1169
Drug Interactions of Concern to Dentistry 1169
Serious Reactions 1169
Dental Considerations 1169
General: 1169
Consultations: 1169
Teach Patient/Family to: 1169
quinapril 1170
Category and Schedule 1170
Drug Class: 1170
Mechanism of Action 1170
Uses 1170
Pharmacokinetics 1170
Indications and Dosages 1170
► Hypertension (Monotherapy) 1170
quinidine 1172
Category and Schedule 1172
Drug Class: 1172
Mechanism of Action 1172
Uses 1172
Pharmacokinetics 1172
Indications and Dosages 1172
► Maintenance of Normal Sinus Rhythm after Conversion of Atrial Fibrillation or Flutter; Prevention of Premature Atrial, AV, and Ventricular Contractions; Paroxysmal Atrial Tachycardia; Paroxysmal AV Junctional Rhythm; Atrial Fibrillation; Atrial Flutter; Paroxysmal Ventricular Tachycardia Not Associated with Complete Heart Block 1172
PO 1172
quinine 1174
Category and Schedule 1174
Drug Class: 1174
Mechanism of Action 1174
Uses 1174
Pharmacokinetics 1174
Indications and Dosages 1174
► Nocturnal Leg Cramps 1174
rabeprazole sodium 1176
Category And Schedule 1176
Drug Class: 1176
Mechanism Of Action 1176
Uses 1176
Pharmacokinetics 1176
Indications And Dosages 1176
► GERD 1176
raloxifene 1177
Category And Schedule 1177
Drug Class: 1177
Mechanism Of Action 1177
Uses 1177
Pharmacokinetics 1177
Indications And Dosages 1177
► Prevention or Treatment of Osteoporosis 1177
PO 1177
Adults, Elderly. 1177
Side Effects/Adverse Reactions 1177
Frequent 1177
Occasional 1177
Rare 1177
Precautions And Contraindications 1177
Caution: 1178
Drug Interactions Of Concern To Dentistry 1178
Serious Reactions 1178
Dental Considerations 1178
General: 1178
Consultations: 1178
raltegravir 1178
Category And Schedule 1178
Drug Class: 1178
Mechanism Of Action 1178
Uses 1178
Pharmacokinetics 1178
Indications And Dosages 1178
► HIV Infection 1178
PO 1178
Adults. 1178
Adolescents (16 yr). 1178
Side Effects/Adverse Reactions 1178
► Adult 1178
Frequent 1178
Occasional 1178
Precautions And Contraindications 1178
Drug Interactions Of Concern To Dentistry 1179
Serious Reactions 1179
Dental Considerations 1179
General: 1179
Consultations: 1179
Teach Patient/Family to: 1179
ramipril 1179
Category And Schedule 1179
Drug Class: 1179
Mechanism Of Action 1179
Uses 1179
Pharmacokinetics 1179
Indications And Dosages 1180
► Hypertension (Monotherapy) 1180
ranitidine hydrochloride/ranitidine bismuth citrate 1181
Category And Schedule 1181
Drug Class: 1181
Mechanism Of Action 1181
Uses 1181
Pharmacokinetics 1182
Indications And Dosages 1182
► Duodenal Ulcers, Gastric Ulcers, Gastroesophageal Reflux Disease 1182
rasagiline 1183
Category And Schedule 1183
Drug Class: 1183
Mechanism Of Action 1183
Uses 1183
Pharmacokinetics 1183
Indications And Dosages 1183
► Parkinson’s Disease, Monotherapy 1183
regorafenib 1184
Category and Schedule 1184
Drug Class: 1184
Mechanism of Action 1185
Uses 1185
Pharmacokinetics 1185
Indications and Dosages 1185
► Colorectal Cancer, Metastatic 1185
repaglinide 1186
Category And Schedule 1186
Drug Class: 1186
Mechanism Of Action 1186
Uses 1186
Pharmacokinetics 1186
Indications And Dosages 1186
► Diabetes Mellitus 1186
PO 1186
Adults, Elderly. 1186
Side Effects/Adverse Reactions 1187
Frequent 1187
Occasional 1187
Rare 1187
Precautions And Contraindications 1187
Caution: 1187
Drug Interactions Of Concern To Dentistry 1187
Serious Reactions 1187
Dental Considerations 1187
General: 1187
Consultations: 1187
Teach Patient/Family to: 1187
reserpine 1187
Category And Schedule 1187
Drug Class: 1187
Mechanism Of Action 1188
Uses 1188
Pharmacokinetics 1188
Indications And Dosages 1188
► Hypertension 1188
retapamulin 1189
Category And Schedule 1189
Drug Class: 1189
Mechanism Of Action 1189
Uses 1189
Pharmacokinetics 1189
Indications And Dosages 1189
► Impetigo Caused by Staphylococcus aureus or Streptococcus pyogenes 1189
Topical 1189
Adults. 1189
Children (9 mo or older). 1189
Side Effects/Adverse Reactions 1189
Occasional 1189
► Adults 1189
► Children 1189
Precautions And Contraindications 1189
reteplase, recombinant 1190
Category And Schedule 1190
Drug Class: 1190
Mechanism Of Action 1190
Uses 1190
Pharmacokinetics 1190
Indications And Dosages 1190
► Acute MI, CHF 1190
IV Bolus 1190
Adults, Elderly. 1190
Side Effects/Adverse Reactions 1190
Frequent 1190
Precautions And Contraindications 1190
Drug Interactions Of Concern To Dentistry 1190
Serious Reactions 1190
Dental Considerations 1190
General: 1190
Consultations: 1190
Teach Patient/Family to: 1190
Dental Considerations 1191
General: 1191
Consultations: 1191
Teach Patient/Family to: 1191
ribavirin 1191
Category And Schedule 1191
Drug Class: 1191
Mechanism Of Action 1191
Uses 1191
Pharmacokinetics 1191
Indications And Dosages 1192
► Chronic Hepatitis C 1192
PO (Capsule or Oral Solution in Combination with Interferon Alfa-2b) 1192
rifabutin 1193
Category And Schedule 1193
Drug Class: 1193
Mechanism Of Action 1193
Uses 1193
Pharmacokinetics 1193
Indications And Dosages 1193
► Prevention of MAC Disease (First Episode) 1193
PO 1193
Adults, Elderly. 1193
► Prevention of Recurrent MAC Disease 1194
PO 1194
Adults, Elderly. 1194
► Dosage in Renal Impairment 1194
Side Effects/Adverse Reactions 1194
Frequent 1194
Occasional 1194
Rare 1194
Precautions And Contraindications 1194
Caution: 1194
Drug Interactions Of Concern To Dentistry 1194
Serious Reactions 1194
Dental Considerations 1194
General: 1194
Consultations: 1194
Teach Patient/Family to: 1194
rifampin 1194
Category And Schedule 1194
Drug Class: 1194
Mechanism Of Action 1194
Uses 1195
Pharmacokinetics 1195
Indications And Dosages 1195
► Tuberculosis 1195
rifapentine 1196
Category And Schedule 1196
Drug Class: 1196
Mechanism Of Action 1196
Uses 1197
Pharmacokinetics 1197
Indications And Dosages 1197
► TB 1197
PO 1197
Adults, Elderly. 1197
Side Effects/Adverse Reactions 1197
Rare 1197
Precautions And Contraindications 1197
Caution: 1197
Drug Interactions Of Concern To Dentistry 1197
Serious Reactions 1197
Dental Considerations 1197
General: 1197
Consultations: 1197
Teach Patient/Family to: 1198
rifaximin 1198
Category and Schedule 1198
Drug Class: 1198
Mechanism of Action 1198
Uses 1198
Pharmacokinetics 1198
Indications and Dosages 1198
► Reduction of Overt Hepatic Encephalopathy Recurrence 1198
rilpivirine 1199
Category and Schedule 1199
Drug Class: 1199
Mechanism of Action 1199
Uses 1199
Pharmacokinetics 1199
Indications and Dosages 1199
► Treatment of HIV-1 Infection 1199
PO 1199
Adults. 1199
Side Effects/Adverse Reactions 1199
Frequent 1199
Occasional 1199
Precautions and Contraindications 1200
Drug Interactions of Concern to Dentistry 1200
Serious Reactions 1200
Dental Considerations 1200
General: 1200
Consultations: 1200
Teach Patient/Family to: 1200
riluzole 1200
Category And Schedule 1200
Drug Class: 1200
Mechanism Of Action 1200
Uses 1200
Pharmacokinetics 1200
Indications And Dosages 1200
► ALS 1200
PO 1200
Adults, Elderly. 1200
Side Effects/Adverse Reactions 1200
Frequent 1200
Occasional 1200
Precautions And Contraindications 1201
Drug Interactions Of Concern To Dentistry 1201
Serious Reactions 1201
Dental Considerations 1201
General: 1201
Consultations: 1201
Teach Patient/Family to: 1201
rimantadine hydrochloride 1201
Category And Schedule 1201
Drug Class: 1201
Mechanism Of Action 1201
Uses 1202
Pharmacokinetics 1202
Indications And Dosages 1202
► Influenza A Virus 1202
rimexolone 1202
Category And Schedule 1202
Drug Class: 1202
risedronate sodium 1203
Category And Schedule 1203
Drug Class: 1203
Mechanism Of Action 1203
Uses 1203
Pharmacokinetics 1203
Indications And Dosages 1203
► Inflammation after Ocular Surgery, Treatment of Anterior Uveitis 1203
Ophthalmic 1203
Adults, Elderly. 1203
Side Effects/Adverse Reactions 1203
Occasional 1203
Precautions And Contraindications 1203
Caution: 1203
Drug Interactions Of Concern To Dentistry 1203
Serious Reactions 1203
Dental Considerations 1203
General: 1203
Indications And Dosages 1204
► Paget’s Disease 1204
risperidone 1204
Category And Schedule 1204
Drug Class: 1204
Mechanism Of Action 1204
Uses 1205
Pharmacokinetics 1205
Indications And Dosages 1205
► Psychotic Disorder 1205
ritonavir 1206
Category And Schedule 1206
Drug Class: 1206
Mechanism Of Action 1206
Uses 1207
Pharmacokinetics 1207
Indications And Dosages 1207
► HIV Infection 1207
PO 1207
Adults, Children 12 yr and older. 1207
Children younger than 12 yr. 1207
Side Effects/Adverse Reactions 1207
Frequent 1207
Occasional 1207
Rare 1207
Precautions And Contraindications 1207
Caution: 1207
Drug Interactions Of Concern To Dentistry 1207
Serious Reactions 1207
Dental Considerations 1208
General: 1208
Consultations: 1208
Teach Patient/Family to: 1208
rituximab 1208
Category And Schedule 1208
Drug Class: 1208
Mechanism Of Action 1208
Uses 1208
Pharmacokinetics 1208
Indications And Dosages 1208
► Non-Hodgkin’s Lymphoma 1208
IV 1208
Adults. 1208
Side Effects/Adverse Reactions 1208
Frequent 1208
Occasional 1208
Precautions And Contraindications 1208
Drug Interactions Of Concern To Dentistry 1208
Serious Reactions 1208
Dental Considerations 1209
General: 1209
Consultations: 1209
Teach Patient/Family to: 1209
rivaroxaban 1209
Category and Schedule 1209
Drug Class: 1209
Mechanism of Action 1209
Uses 1209
Pharmacokinetics 1209
Indications and Dosages 1210
► Nonvalvular Atrial Fibrillation (to Prevent Stroke and Systemic Embolism) 1210
rivastigmine tartrate 1211
Category And Schedule 1211
Drug Class: 1211
Mechanism Of Action 1211
Pharmacokinetics 1211
Indications And Dosages 1211
► Alzheimer’s Disease 1211
PO 1211
Adults, Elderly. 1211
Side Effects/Adverse Reactions 1211
Frequent 1211
Occasional 1211
Rare 1211
Precautions And Contraindications 1211
Caution: 1211
Drug Interactions Of Concern To Dentistry 1211
Serious Reactions 1211
Dental Considerations 1211
General: 1211
Consultations: 1212
Teach Patient/Family to: 1212
rizatriptan benzoate 1212
Category And Schedule 1212
Drug Class: 1212
Mechanism Of Action 1212
Uses 1212
Pharmacokinetics 1212
Indications And Dosages 1212
► Acute Migraine Attack 1212
PO 1212
Adults older than 18 yr, Elderly. 1212
Side Effects/Adverse Reactions 1212
Frequent 1212
Occasional 1212
Rare 1213
Precautions And Contraindications 1213
Caution: 1213
Drug Interactions Of Concern To Dentistry 1213
Serious Reactions 1213
Dental Considerations 1213
General: 1213
Consultations: 1213
Teach Patient/Family to: 1213
roflumilast 1213
Category and Schedule 1213
Drug Class: 1213
Mechanism of Action 1213
ropinirole hydrochloride 1214
Category And Schedule 1214
Drug Class: 1214
Mechanism Of Action 1214
Uses 1214
Pharmacokinetics 1214
Indications and Dosages 1214
► COPD 1214
PO 1214
Adults. 1214
Side Effects/Adverse Reactions 1214
Frequent 1214
Occasional 1214
Precautions and Contraindications 1214
Drug Interactions of Concern to Dentistry 1214
Serious Reactions 1214
Dental Considerations 1214
General: 1214
Teach Patient/Family to: 1214
Pharmacokinetics 1215
Indications And Dosages 1215
► Parkinson’s Disease 1215
PO 1215
Adults, Elderly. 1215
Side Effects/Adverse Reactions 1215
Frequent 1215
Occasional 1215
Rare 1215
Precautions And Contraindications: Hypersensitivity 1215
Drug Interactions Of Concern To Dentistry 1215
Serious Reactions 1215
Dental Considerations 1215
General: 1215
Consultations: 1215
Teach Patient/Family to: 1215
rosiglitazone maleate 1216
Category And Schedule 1216
Drug Class: 1216
Mechanism Of Action 1216
Uses 1216
Pharmacokinetics 1216
Indications And Dosages 1216
► Diabetes Mellitus, Combination Therapy 1216
PO 1216
rosuvastatin calcium 1217
Category And Schedule 1217
Drug Class: 1217
Mechanism Of Action 1217
Uses 1217
Pharmacokinetics 1217
Indications And Dosages 1217
► Hyperlipidemia, Dyslipidemia 1217
rotigotine 1218
Category and Schedule 1218
Drug Class: 1218
Mechanism of Action 1218
Uses 1218
Pharmacokinetics 1218
Indications and Dosages 1219
► Parkinson’s Disease 1219
sacubitril + valsartan 1220
Category and Schedule 1220
Drug Class: 1220
Mechanism of Action 1220
Uses 1220
Pharmacokinetics 1220
Indications and Dosages 1220
► Heart Failure 1220
PO 1220
Adults. 1220
Side Effects/Adverse Reactions 1220
Frequent 1220
Occasional 1220
Precautions and Contraindications 1220
Drug Interactions of Concern to Dentistry 1221
Serious Reactions 1221
Dental Considerations 1221
General: 1221
Consultations: 1221
Teach Patient/Family to: 1221
salmeterol 1221
Category And Schedule 1221
Drug Class: 1221
Mechanism Of Action 1221
Uses 1221
Pharmacokinetics 1221
Indications And Dosages 1221
► Prevention and Maintenance Treatment of Asthma 1221
Inhalation (Diskus) 1221
Adults, Elderly, Children 4 yr and older. 1221
► Prevention of Exercise-Induced Bronchospasm 1222
salsalate 1222
Category And Schedule 1222
Drug Class: 1222
Mechanism Of Action 1222
Uses 1223
Pharmacokinetics 1223
Indications And Dosages 1223
► Rheumatoid Arthritis, Osteoarthritis Pain 1223
PO 1223
Adults, Elderly. 1223
Side Effects/Adverse Reactions 1223
Occasional 1223
Precautions And Contraindications 1223
Caution: 1223
Drug Interactions Of Concern To Dentistry 1223
Serious Reactions 1223
Dental Considerations 1223
General: 1223
Consultations: 1224
Teach Patient/Family to: 1224
sapropterin 1224
Category And Schedule 1224
Drug Class: 1224
Mechanism Of Action 1224
Uses 1224
Pharmacokinetics 1224
Indications And Dosages 1224
► Management of Phenylketonuria 1224
Adult. 1224
Side Effects/Adverse Reactions 1224
Frequent 1224
Occasional 1225
Precautions And Contraindications 1225
Drug Interactions Of Concern To Dentistry 1225
Serious Reactions 1225
Dental Considerations 1225
General: 1225
Consultations: 1225
Teach Patient/Family to: 1225
saquinavir 1225
Category And Schedule 1225
Drug Class: 1225
Mechanism Of Action 1225
Uses 1226
Pharmacokinetics 1226
Indications And Dosages 1226
► HIV Infection in Combination with Other Antiretrovirals 1226
PO 1226
Adults, Elderly. 1226
► Dosage Adjustments When Given in Combination Therapy 1226
Side Effects/Adverse Reactions 1226
Occasional 1226
Rare 1226
Precautions And Contraindications 1226
Caution: 1226
Drug Interactions Of Concern To Dentistry 1226
Serious Reactions 1226
Dental Considerations 1226
General: 1226
Consultations: 1226
Teach Patient/Family to: 1226
sargramostim (granulocyte macrophage colony-stimulating factor, GM-CSF) 1227
Category And Schedule 1227
Drug Class: 1227
Mechanism Of Action 1227
Uses 1227
Pharmacokinetics 1227
Indications And Dosages 1227
► Myeloid Recovery Following Bone Marrow Transplant (BMT) 1227
saxagliptin 1228
Category And Schedule 1228
Drug Class: 1228
Mechanism Of Action 1229
Uses 1229
Pharmacokinetics 1229
Indications And Dosages 1229
► Type 2 Diabetes Mellitus 1229
PO 1229
Adults. 1229
Concurrent use with strong CYP3A4/5 inhibitors. 1229
► Dosage in Renal Impairment 1229
Mild impairment (CrCl greater than 50 ml/min). 1229
Moderate to severe impairment (CrCl 50 ml/min or less). 1229
ESRD requiring dialysis. 1229
Side Effects/Adverse Reactions 1229
Frequent 1229
Occasional 1229
Rare 1229
Precautions And Contraindications 1229
Caution: 1229
Drug Interactions Of Concern To Dentistry 1229
Serious Reactions 1229
Dental Considerations 1229
General: 1229
Consultations: 1230
Teach Patient/Family to: 1230
scopolamine 1230
Category And Schedule 1230
Drug Class: 1230
Mechanism Of Action 1230
Uses 1230
Pharmacokinetics 1230
Indications And Dosages 1230
► Prevention of Motion Sickness 1230
secobarbital 1231
Category And Schedule 1231
Drug Class: 1231
Mechanism Of Action 1231
Uses 1231
Pharmacokinetics 1231
Indications And Dosages 1231
► Insomnia 1231
selegiline hydrochloride 1233
Category And Schedule 1233
Drug Class: 1233
Mechanism Of Action 1233
Uses 1233
Pharmacokinetics 1233
Indications And Dosages 1233
► Adjunctive Treatment for Parkinsonism 1233
PO 1233
Adults. 1233
Elderly. 1233
Side Effects/Adverse Reactions 1233
Frequent 1233
Occasional 1233
Rare 1233
Precautions And Contraindications 1233
Caution: 1233
Drug Interactions Of Concern To Dentistry 1233
Serious Reactions 1233
Dental Considerations 1234
General: 1234
Consultations: 1234
Teach Patient/Family to: 1234
sertaconazole 1234
Category And Schedule 1234
Drug Class: 1234
Mechanism Of Action 1234
Uses 1234
Pharmacokinetics 1234
Indications And Dosages 1234
► Tinea Pedis 1234
Topical 1234
Adults, Elderly, Children 12 yr and older. 1234
Side Effects/Adverse Reactions 1234
Rare 1234
Precautions And Contraindications 1234
Drug Interactions Of Concern To Dentistry 1234
Serious Reactions 1235
Dental Considerations 1235
General: 1235
sertraline 1235
Category And Schedule 1235
Drug Class: 1235
Mechanism Of Action 1235
Uses 1235
Pharmacokinetics 1235
Indications And Dosages 1235
► Depression 1235
sevelamer hydrochloride 1237
Category And Schedule 1237
Drug Class: 1237
Mechanism Of Action 1237
Uses 1237
Pharmacokinetics 1237
Indications And Dosages 1237
► Hyperphosphatemia 1237
PO 1237
Adults, Elderly. 1237
Side Effects/Adverse Reactions 1237
Frequent 1237
Occasional 1237
Precautions And Contraindications 1237
Drug Interactions Of Concern To Dentistry 1237
Serious Reactions 1237
Dental Considerations 1237
General: 1237
Consultations: 1237
Teach Patient/Family to: 1238
sildenafil citrate 1238
Category And Schedule 1238
Drug Class: 1238
Mechanism Of Action 1238
Uses 1238
Pharmacokinetics 1238
Indications And Dosages 1238
► Erectile Dysfunction 1238
PO 1238
Adults. 1238
Elderly older than 65 yr. 1238
Side Effects/Adverse Reactions 1238
Frequent 1238
Occasional 1238
Rare 1238
Precautions And Contraindications 1238
Caution: 1238
Drug Interactions Of Concern To Dentistry 1239
Serious Reactions 1239
Dental Considerations 1239
General: 1239
silodosin 1239
Category and Schedule 1239
Drug Class: 1239
Mechanism of Action 1239
Uses 1239
Pharmacokinetics 1239
Indications and Dosages 1239
► Benign Prostatic Hyperplasia 1239
PO 1239
Adults. 1239
► Renal Impairment 1239
Side Effects/Adverse Reactions 1239
Frequent 1239
Occasional 1239
Precautions and Contraindications 1239
Drug Interactions of Concern to Dentistry 1240
Serious Reactions 1240
Dental Considerations 1240
General: 1240
Teach Patient/Family to: 1240
simethicone 1240
Category And Schedule 1240
Drug Class: 1240
Mechanism Of Action 1240
Uses 1240
Pharmacokinetics 1240
Indications And Dosages 1240
► Antiflatulent 1240
PO 1240
Adults, Elderly, Children 12 yr and older. 1240
Children 2–11 yr. 1240
Children younger than 2 yr. 1240
Side Effects/Adverse Reactions 1240
Precautions And Contraindications 1241
Drug Interactions Of Concern To Dentistry 1241
Serious Reactions 1241
Dental Considerations 1241
General: 1241
Teach Patient/Family to: 1241
simvastatin 1241
Category And Schedule 1241
Drug Class: 1241
Mechanism Of Action 1241
Uses 1241
Pharmacokinetics 1241
Indications And Dosages 1242
► Adjunct to Diet to Decrease Heterozygous Familial Hypercholesterolemia in Adolescents 10–17 Yr of Age (Girls at Least 1-Yr Post-menarche) 1242
Heterozygous Familial Hypercholesterolemia 1242
tacrine hydrochloride 1275
Category And Schedule 1275
Drug Class: 1275
Cholinesterase Inhibitor 1275
Mechanism Of Action 1275
Uses 1275
Pharmacokinetics 1275
Indications And Dosages 1275
► Alzheimer’s Disease 1275
PO 1275
Adults, Elderly. 1275
► Dosage in Hepatic Impairment 1275
Side Effects/Adverse Reactions 1275
Frequent 1275
Occasional 1275
Rare 1275
Precautions And Contraindications 1275
Caution: 1275
Drug Interactions Of Concern To Dentistry 1275
Serious Reactions 1275
Dental Considerations 1276
General: 1276
Consultations: 1276
Teach Patient/Family to: 1276
tacrolimus 1276
Category And Schedule 1276
Drug Class: 1276
Mechanism Of Action 1276
Uses 1276
Pharmacokinetics 1276
Indications And Dosages 1277
► Prevention of Liver Transplant Rejection 1277
ulipristal 1393
Category and Schedule 1393
Drug Class: 1393
Mechanism of Action 1393
Uses 1393
Pharmacokinetics 1393
Indications and Dosages 1393
► Emergency Contraception 1393
PO 1393
Adults (females). 1393
Side Effects/Adverse Reactions 1393
Frequent 1393
Occasional 1393
Precautions and Contraindications 1393
Drug Interactions of Concern to Dentistry 1393
Serious Reactions 1393
Dental Considerations 1393
General: 1393
Teach Patient/Family to: 1393
Uses 1394
Pharmacokinetics 1394
Indications and Dosages 1394
► Chronic Obstructive Pulmonary Disease (COPD) 1394
Adults. 1394
Side Effects/Adverse Reactions 1394
Frequent 1394
Occasional 1394
Precautions and Contraindications 1394
Drug Interactions of Concern to Dentistry 1394
Serious Reactions 1394
Dental Considerations 1394
General: 1394
Consultations: 1395
Teach Patient/Family to: 1395
umeclidinium + vilanterol 1393
unoprostone isopropyl 1395
Category And Schedule 1395
Drug Class: 1395
Mechanism Of Action 1395
Uses 1395
Pharmacokinetics 1395
Indications And Dosages 1395
► Glaucoma, Ocular Hypertension 1395
Ophthalmic 1395
Adults, Elderly. 1395
Side Effects/Adverse Reactions 1395
Frequent 1395
Occasional 1395
Precautions And Contraindications 1395
Caution: 1395
ursodiol 1396
Category And Schedule 1396
Drug Class: 1396
Mechanism Of Action 1396
Uses 1396
Indications And Dosages 1396
► Dissolution of Radiolucent, Noncalcified Gallstones When Cholecystectomy Is Not Recommended; Treatment of Biliary Cirrhosis 1396
valacyclovir 1398
Category and Schedule 1398
Drug Class: 1398
Mechanism of Action 1398
Uses 1398
Pharmacokinetics 1398
Indications and Dosages 1398
► Herpes Zoster (shingles) 1398
valganciclovir hydrochloride 1399
Category and Schedule 1399
Drug Class: 1399
Mechanism of Action 1399
Uses 1399
Pharmacokinetics 1399
Indications and Dosages 1399
► CMV Retinitis in Patients with Normal Renal Function 1399
valproic acid/valproate sodium/divalproex sodium 1401
Category and Schedule 1401
Drug Class: 1401
Mechanism of Action 1401
Uses 1401
Pharmacokinetics 1401
Indications and Dosages 1401
► Seizures 1401
valrubicin 1402
Category and Schedule 1402
Drug Class: 1402
Mechanism of Action 1402
Uses 1403
Pharmacokinetics 1403
Indications and Dosages 1403
► Bladder Cancer 1403
Intravesical 1403
Adults, Elderly. 1403
Side Effects/Adverse Reactions 1403
Frequent 1403
Occasional 1403
Rare 1403
Precautions and Contraindications 1403
Drug Interactions of Concern to Dentistry 1403
Serious Reactions 1403
Dental Considerations 1403
General: 1403
Consultations: 1403
Teach Patient/Family to: 1403
valsartan 1404
Category and Schedule 1404
Drug Class: 1404
Mechanism of Action 1404
Uses 1404
Pharmacokinetics 1404
Indications and Dosages 1404
► Hypertension 1404
vancomycin hydrochloride 1405
Category and Schedule 1405
Drug Class: 1405
Mechanism of Action 1405
Uses 1405
Pharmacokinetics 1405
Indications and Dosages 1405
► Treatment of Bone, Respiratory Tract, Skin, and Soft Tissue Infections; Endocarditis, Peritonitis, and Septicemia; Prevention of Bacterial Endocarditis in Those at Risk (If Penicillin Is Contraindicated) When Undergoing Biliary, Dental, GI, GU, or Respiratory Surgery or Invasive Procedures 1405
IV 1405
vardenafil 1406
Category and Schedule 1406
Drug Class: 1406
Mechanism of Action 1406
Uses 1406
Pharmacokinetics 1406
Indications and Dosages 1406
► Erectile Dysfunction 1406
PO 1406
Adults. 1406
Elderly, older than 65 yr. 1406
► Dosage in Moderate Hepatic Impairment 1407
varenicline 1407
Category and Schedule 1407
Drug Class: 1407
Mechanism of Action 1408
Uses 1408
Pharmacokinetics 1408
Indications and Dosages 1408
► Aid to Smoking Cessation 1408
Adult. 1408
Side Effects/Adverse Reactions 1408
Frequent 1408
Occasional 1408
Rare 1408
Precautions and Contraindications 1408
Drug Interactions of Concern to Dentistry 1408
Dental Considerations 1408
General: 1408
Consultations: 1408
Teach Patient/Family: 1408
vasopressin 1409
Category and Schedule 1409
Drug Class: 1409
Mechanism of Action 1409
Uses 1409
Pharmacokinetics 1409
Indications and Dosages 1409
► Cardiac Arrest 1409
venlafaxine 1410
Category and Schedule 1410
Drug Class: 1410
Mechanism of Action 1410
Uses 1410
Pharmacokinetics 1410
Indications and Dosages 1410
► Depression 1410
PO 1410
verapamil hydrochloride 1412
Category and Schedule 1412
Drug Class: 1412
Mechanism of Action 1412
Uses 1412
Pharmacokinetics 1412
Indications and Dosages 1412
► Supraventricular Tachyarrhythmias, Temporary Control of Rapid Ventricular Rate with Atrial Fibrillation or Flutter 1412
IV 1412
Adults, Elderly. 1412
Children 1–15 yr. 1412
► Arrhythmias, Including Prevention of Recurrent Paroxysmal Supraventricular Tachycardia and Control of Ventricular Resting Rate in Chronic Atrial Fibrillation or Flutter (with Digoxin) 1413
vidarabine 1414
Category and Schedule 1414
Drug Class: 1414
Mechanism of Action 1414
Uses 1414
Pharmacokinetics 1414
Indications and Dosages 1414
► Treatment of Keratitis, Keratoconjunctivitis Caused by Human Herpes Virus, Types 1 and 2 1414
Ophthalmic 1414
Adults, Elderly. 1414
Side Effects/Adverse Reactions 1414
Frequent 1414
Occasional 1414
vigabatrin 1415
Category and Schedule 1415
Drug Class: 1415
Mechanism of Action 1415
Uses 1415
Pharmacokinetics 1415
Indications and Dosages 1415
► Partial-Onset Seizures 1415
Adult. 1415
Side Effects/Adverse Reactions 1415
Frequent 1415
Occasional 1415
Precautions and Contraindications 1415
Caution: 1415
Drug Interactions of Concern to Dentistry 1415
Serious Reactions 1415
Dental Considerations 1415
General: 1415
Teach Patient/Family to: 1415
Dental Considerations 1416
General: 1416
Consultations: 1416
Teach Patient/Family to: 1416
vilazodone 1416
Category and Schedule 1416
Drug Class: 1416
Mechanism of Action 1416
Uses 1416
Pharmacokinetics 1416
Indications and Dosages 1416
► Depression 1416
PO 1416
Adults. 1416
Side Effects/Adverse Reactions 1416
Frequent 1416
Occasional 1416
Precautions and Contraindications 1416
Drug Interactions of Concern to Dentistry 1417
Serious Reactions 1417
Dental Considerations 1417
General: 1417
Consultations: 1417
Teach Patient/Family to: 1417
vinblastine sulfate 1417
Category and Schedule 1417
Drug Class: 1417
Mechanism of Action 1417
Uses 1417
Pharmacokinetics 1417
Indications and Dosages 1417
► Remission Induction in Advanced Testicular Carcinoma, Advanced Mycosis Fungoides, Breast Carcinoma, Choriocarcinoma, Disseminated Hodgkin’s Disease, Non-Hodgkin’s Lymphoma, Kaposi’s Sarcoma (KS), or Letterer-Siwe Disease 1417
IV 1417
Adults, Elderly. 1417
Children. 1418
► Maintenance Dose for Treatment of Advanced Testicular Carcinoma, Advanced Mycosis Fungoides, Breast Carcinoma, Choriocarcinoma, Disseminated Hodgkin’s Disease, Non-Hodgkin’s Lymphoma, KS, or Letterer-Siwe Disease 1418
IV 1418
Adults, Elderly, Children. 1418
Side Effects/Adverse Reactions 1418
Frequent 1418
Occasional 1418
Rare 1418
Precautions and Contraindications 1418
Drug Interactions of Concern to Dentistry 1418
Serious Reactions 1418
Dental Considerations 1418
General: 1418
Consultations: 1419
Teach Patient/Family to: 1419
vincristine sulfate 1419
Category and Schedule 1419
Drug Class: 1419
Mechanism of Action 1419
Uses 1419
Pharmacokinetics 1419
Indications and Dosages 1420
► Acute Leukemia, Advanced Non-Hodgkin’s Lymphoma, Disseminated Hodgkin’s Disease, Neuroblastoma, Rhabdomyosarcoma, Wilms’ Tumor 1420
IV 1420
Adults, Elderly. 1420
Children. 1420
Children weighing less than 10 kg or with a body surface area less than 1 m2 0.05 mg/kg. 1420
► Dosage in Hepatic Impairment 1420
Side Effects/Adverse Reactions 1420
Expected 1420
Frequent 1420
Occasional 1420
Rare 1420
Precautions and Contraindications 1420
Drug Interactions of Concern to Dentistry 1420
Serious Reactions 1420
Dental Considerations 1420
General: 1420
Consultations: 1421
Teach Patient/Family to: 1421
vinorelbine 1421
Category and Schedule 1421
Drug Class: 1421
Mechanism of Action 1421
Uses 1421
Pharmacokinetics 1421
Indications and Dosages 1421
► Unresectable, Advanced Non–Small-Cell Lung Cancer (as Monotherapy or in Combination with Cisplatin) 1421
IV 1421
Adults, Elderly. 1421
► Dosage Adjustment Guidelines 1421
► Combination Therapy (with Cisplatin) 1422
IV Injection 1422
Adults, Elderly. 1422
Side Effects/Adverse Reactions 1422
Frequent 1422
Occasional 1422
Rare 1422
Precautions and Contraindications 1422
Drug Interactions of Concern to Dentistry 1422
Serious Reactions 1422
Dental Considerations 1422
General: 1422
Consultations: 1422
Teach Patient/Family to: 1423
vismodegib 1423
Category and Schedule 1423
Drug Class: 1423
Mechanism of Action 1423
Uses 1423
Pharmacokinetics 1423
Indications and Dosages 1423
► Basal Cell Cancer, Metastatic or Locally Advanced 1423
PO 1423
Adults. 1423
Side Effects/Adverse Reactions 1423
Frequent 1423
Occasional 1423
Precautions and Contraindications 1423
Drug Interactions of Concern to Dentistry 1423
Serious Reactions 1423
Dental Considerations 1424
General: 1424
Consultations: 1424
Teach Patient/Family to: 1424
vorapaxar 1424
Category and Schedule 1424
Drug Class: 1424
Mechanism of Action 1424
Uses 1424
Pharmacokinetics 1424
Indications and Dosages 1424
► History of MI or PAD 1424
PO 1424
Adults. 1424
Side Effects/Adverse Reactions 1424
Frequent 1424
Occasional 1424
Precautions and Contraindications 1424
Drug Interactions of Concern to Dentistry 1424
Serious Reactions 1424
Dental Considerations 1425
General: 1425
Consultations: 1425
Teach Patient/Family to: 1425
vortioxetine 1425
Category and Schedule 1425
Drug Class: 1425
Mechanism of Action 1425
Uses 1425
Pharmacokinetics 1425
Indications and Dosages 1425
► Major Depressive Disorder 1425
PO 1425
Adults. 1425
Side Effects/Adverse Reactions 1425
Frequent 1425
Occasional 1426
Precautions and Contraindications 1426
Drug Interactions of Concern to Dentistry 1426
Serious Reactions 1426
Dental Considerations 1426
General: 1426
Consultations: 1426
Teach Patient/Family to: 1426
warfarin sodium 1427
Category and Schedule 1427
Drug Class: 1427
Mechanism of Action 1427
Uses 1427
Pharmacokinetics 1427
Indications and Dosages 1427
Anticoagulant 1427
PO 1427
Adults, Elderly. 1427
Children. 1427
Usual Elderly Dosage (Maintenance) 1427
PO, IV 1427
Elderly. 1427
Side Effects/Adverse Reactions 1427
Occasional 1427
Rare 1427
Precautions and Contraindications 1427
Caution: 1427
Drug Interactions of Concern to Dentistry 1427
Serious Reactions 1428
Dental Considerations 1428
General: 1428
Consultations: 1428
Teach Patient/Family to: 1428
zafirlukast 1429
Category and Schedule 1429
Drug Class: 1429
Mechanism of Action 1429
Uses 1429
Pharmacokinetics 1429
Indications and Dosages 1429
► Bronchial Asthma 1429
PO 1429
Adults, Elderly, Children 12 yr and older. 1429
Children 5–11 yr. 1429
Side Effects/Adverse Reactions 1429
Frequent 1429
Occasional 1429
Rare 1429
Precautions and Contraindications 1429
Caution: 1429
Drug Interactions of Concern to Dentistry 1429
Serious Reactions 1429
Dental Considerations 1430
General: 1430
Consultations: 1430
Teach Patient/Family to: 1430
zalcitabine 1430
Category and Schedule 1430
Drug Class: 1430
Mechanism of Action 1430
Uses 1430
Pharmacokinetics 1430
Indications and Dosages 1430
► HIV Infection (in Combination with Other Antiretrovirals) 1430
PO 1430
Adults, Children 13 yr and older. 1430
Children younger than 13 yr. 1430
► Dosage in Renal Impairment 1430
Side Effects/Adverse Reactions 1430
Frequent 1430
Occasional 1431
Rare 1431
Precautions and Contraindications 1431
Caution: 1431
Drug Interactions of Concern to Dentistry 1431
Serious Reactions 1431
Dental Considerations 1431
General: 1431
Consultations: 1431
Teach Patient/Family to: 1431
zaleplon 1431
Category and Schedule 1431
Drug Class: 1431
Mechanism of Action 1432
Uses 1432
Pharmacokinetics 1432
Indications and Dosages 1432
► Insomnia 1432
PO 1432
Adults. 1432
Elderly. 1432
Side Effects/Adverse Reactions 1432
Expected 1432
Frequent 1432
Occasional 1432
Rare 1432
Precautions and Contraindications 1432
Caution: 1432
Drug Interactions of Concern to Dentistry 1432
Serious Reactions 1432
Dental Considerations 1432
General: 1432
Consultations: 1432
Teach Patient/Family to: 1432
zanamivir 1433
Category and Schedule 1433
Drug Class: 1433
Mechanism of Action 1433
Uses 1433
Pharmacokinetics 1433
Indications and Dosages 1433
► Influenza Virus 1433
ziconotide 1434
Category and Schedule 1434
Drug Class: 1434
Mechanism of Action 1434
Uses 1434
Pharmacokinetics 1434
Indications and Dosages 1434
► Pain Control 1434
Intrathecal 1434
Adults, Elderly. 1434
Side Effects/Adverse Reactions 1434
Frequent 1434
Occasional 1434
Rare 1434
Precautions and Contraindications 1434
Drug Interactions of Concern to Dentistry 1434
Serious Reactions 1434
Dental Considerations 1434
General: 1434
Consultations: 1434
Teach Patient/Family to: 1434
zidovudine 1435
Category and Schedule 1435
Drug Class: 1435
Mechanism of Action 1435
Uses 1435
Pharmacokinetics 1435
Indications and Dosages 1435
► HIV Infection 1435
PO 1435
zileuton 1436
Category and Schedule 1436
Drug Class: 1436
Mechanism of Action 1436
Uses 1436
Pharmacokinetics 1436
Indications and Dosages 1436
► Bronchial Asthma 1436
PO 1436
Adults, Elderly, Children 12 yr and older. 1436
Side Effects/Adverse Reactions 1437
Frequent 1437
Occasional 1437
Rare 1437
Precautions and Contraindications 1437
Caution: 1437
Drug Interactions of Concern to Dentistry 1437
Serious Reactions 1437
Dental Considerations 1437
General: 1437
Consultations: 1437
Teach Patient/Family to: 1437
ziprasidone 1437
Category and Schedule 1437
Drug Class: 1437
Mechanism of Action 1437
Uses 1437
Pharmacokinetics 1437
Indications and Dosages 1438
► Schizophrenia 1438
zoledronic acid 1439
Category and Schedule 1439
Drug Class: 1439
Mechanism of Action 1439
Uses 1439
Pharmacokinetics 1439
Indications and Dosages 1439
► Hypercalcemia 1439
IV Infusion 1439
zolmitriptan 1440
Category and Schedule 1440
Drug Class: 1440
Mechanism of Action 1440
Uses 1440
Pharmacokinetics 1440
Indications and Dosages 1440
► Acute Migraine Attack 1440
PO 1440
Adults, Elderly, Children older than 18 yr. 1440
Intranasal 1441
Adults, Elderly. 1441
Side Effects/Adverse Reactions 1441
Frequent 1441
Occasional 1441
Rare 1441
Precautions and Contraindications 1441
Caution: 1441
Drug Interactions of Concern to Dentistry 1441
Serious Reactions 1441
Dental Considerations 1441
General: 1441
Consultations: 1441
Teach Patient/Family to: 1441
zolpidem tartrate 1442
Category and Schedule 1442
Drug Class: 1442
Mechanism of Action 1442
Uses 1442
Pharmacokinetics 1442
Indications and Dosages 1442
► Insomnia 1442
PO 1442
Adults. 1442
Elderly, Debilitated. 1442
Side Effects/Adverse Reactions 1442
Occasional 1442
Rare 1442
Precautions and Contraindications 1442
Caution: 1442
Drug Interactions of Concern to Dentistry 1442
Serious Reactions 1442
Dental Considerations 1442
General: 1442
Consultations: 1443
Teach Patient/Family to: 1443
zonisamide 1443
Category and Schedule 1443
Drug Class: 1443
Mechanism of Action 1443
Uses 1443
Pharmacokinetics 1443
Indications and Dosages 1443
► Partial Seizures 1443
PO 1443
Adults, Elderly, Children older than 16 yr. 1443
Side Effects/Adverse Reactions 1443
Frequent 1443
Occasional 1443
Rare 1443
Precautions and Contraindications 1443
Caution: 1443
Drug Interactions of Concern to Dentistry 1443
Serious Reactions 1444
Dental Considerations 1444
General: 1444
Consultations: 1444
Teach Patient/Family to: 1444
Appendix A Abbreviations e1
Appendix B Combination Drugs by Trade Name e9
Appendix C Drugs Associated With Dry Mouth e17
Appendix D Drugs That Affect Taste e22
Alcohol Detoxification e22
Alkalosis Agent e22
Alzheimer’s e22
Analgesics (NSAIDS) e22
Anesthetics (General) e22
Anesthetics (Local) e22
Anorexiants e22
Antacids e22
Antagonists e22
Antianemic e22
Antianxiety e22
Antiarthritic e22
Anticholinergics e22
Anticonvulsants e22
Antidepressants e22
Antidiabetics e22
Antidiarrheals e22
Antiemetics e22
Antifungals e22
Antigout e22
Antihyperlipidemics e23
Antiinfectives e23
Antiinflammatory/Antiarthritic e23
Antimigraine e23
Antineoplastic e23
Antiparkinson e23
Antiprotozoal e23
Antipsychotics e23
Antithyroid e23
Antivirals e23
Anxiolytic/Sedatives e23
Asthma Preventives e23
Bronchodilators e23
Calcium-Affecting Drugs e23
Cancer Chemotherapeutics e24
Cardiovascular e24
Cns Stimulants e24
Decongestant e24
Diuretics e24
Glucocorticoids e24
Gallstone Solubilization e24
Hemorheologic e24
Immunomodulators e24
Immunosuppressants e24
Irritable Bowel Syndrome e24
Hypnotic e24
Methylxanthines e24
Nicotine Cessation e24
Ophthalmics e24
Proton Pump Inhibitors e24
Retinoid, Systemic e24
Salivary Stimulant e24
Sedative-Hypnotic e24
Relaxants e25
Vitamins e25
Appendix E Complementary and Alternative Medications and Dietary Supplements e26
aloe vera e26
Other Names: e26
Class: e26
Major Ingredients e26
Claimed Actions e26
Uses e26
Administration e26
Side Effects e26
Appendix F Preventing Medication Errors and Improving Medication Safety e72
Communicating Prescription Information e72
Zeros and Decimal Points e73
Abbreviations e73
Ambiguous or Incomplete Orders e73
High-Alert Medications e73
Appendix G Oral Contraceptives e75
Category and Schedule e75
Drug Class: e75
Mechanism of Action e75
Uses e75
Pharmacokinetics e75
Indications and Dosages e75
► Contraception e75
Generic and Trade Name Index 1445
A 1445
B 1450
C 1452
D 1457
E 1460
F 1462
G 1463
H 1464
I 1467
J 1469
K 1469
L 1470
M 1471
N 1474
O 1476
P 1478
Q 1483
R 1483
S 1485
T 1488
U 1491
V 1491
W 1493
X 1493
Y 1493
Z 1493
Weights and Equivalents IBC1
Metric System IBC1
Weight Conversion, Pounds to Kilograms IBC1
Household Equivalents—Approximate IBC1
Calculations for Determining the Amount of Local Anesthetic and/or Vasoconstrictor in Dental Cartridges IBC2
Typical Local Anesthetic Concentrations IBC2
Typical Vasoconstrictor Concentrations IBC2
General Calculation Guidelines IBC2