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Ruppel's Manual of Pulmonary Function Testing - E-Book

Ruppel's Manual of Pulmonary Function Testing - E-Book

Carl Mottram

(2017)

Additional Information

Book Details

Abstract

Use this authoritative guide as an on-the-job reference — and to prepare for the CPFT and RPFT credentialing examinations! Ruppel's Manual of Pulmonary Function Testing, 11th Edition provides comprehensive coverage of common pulmonary function tests, testing techniques, and the pathophysiology that may be evaluated by each test. It also includes information on equipment, computers, and quality assurance, so you can develop the testing skills you need to find and assess lung abnormalities and conditions including asthma, COPD, emphysema, and cystic fibrosis. Written by Carl Mottram, a well-known expert in pulmonary function procedures, this bestselling guide helps you get accurate test results every time.

  • Entry- and Advanced-Level objectives prepare you for success on the Certified Pulmonary Function Technologist and Registered Pulmonary Function Technologist credentialing examinations, and follow the content guidelines suggested by the CPFT and RPFT exam matrices from the National Board for Respiratory Care (NBRC).
  • How To boxes provide step-by-step guidelines to performing pulmonary function tests, taking the guesswork out of completing accurate and result-producing tests.
  • PFT Tips highlight and reinforce the most important Pulmonary Function Testing information in every chapter. 
  • Case studies provide problem-solving challenges for common clinical cases, including each case history, PFT testing results, a technologist’s comments, and questions and answers.
  • Convenient study features include key terms, chapter outlines, learning objectives, suggested readings, a glossary, and self-assessment questions.
  • Authoritative, comprehensive resource conveys state-of-the-art information, and eliminates the need to search for information in other sources. 
  • Criteria for acceptability and repeatability are included in each test section, as well as interpretive strategies to help you adhere to recognized testing standards.
  • NEW! UPDATED content reflects the latest guidelines, testing procedure recommendations, and interpretive strategies of the American Thoracic Society/European Respiratory Society as well as the newest guidelines for exercise testing from the American Thoracic Society/American College of Chest Physicians. 
  • NEW! Practice tests on the Evolve companion website help you apply the knowledge learned in the text.
  • NEW! Summary Points at the end of chapters reinforce important entry-level and advanced-level concepts.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Inside Front Cover ES2
Ruppel’s manual of Pulmonary Function Testing iii
Copyright iv
Contributors/Reviewers v
Foreword vi
Preface vii
Distinctive features vii
Changes to this edition viii
Using this book viii
Evolve ancillaries viii
Acknowledgments ix
Contents x
Chapter 1: Indications for Pulmonary Function Testing 1
Pulmonary function tests 2
Airway Function Tests 2
Lung Volume and Ventilation Tests 5
Diffusing Capacity Tests 5
Blood Gases and Gas Exchange Tests 6
Cardiopulmonary Exercise Tests 6
Metabolic Measurements 7
Indications for pulmonary function testing 7
Spirometry 7
Lung Volumes 8
Diffusing Capacity 8
Blood Gases 9
Exercise Tests 10
Patterns of impaired pulmonary function 10
Obstructive Airway Diseases 10
Chronic Obstructive Pulmonary Disease 10
Emphysema 11
Chronic Bronchitis 12
Bronchiectasis 13
Management of Chronic Obstructive Pulmonary Disease 14
Hyperreactive Airway Disease: Asthma 15
Management of Asthma 16
Cystic Fibrosis 17
Management of Cystic Fibrosis 18
Upper or Large Airway Obstruction 18
Management of Upper or Large Airway Obstruction 19
Restrictive Lung Disease 19
Pulmonary Fibrosis 20
Pneumoconioses 20
Sarcoidosis 21
Diseases of the Chest Wall and Pleura 22
Neuromuscular Disorders 23
Congestive Heart Failure 24
Lung Transplantation 25
Preliminaries to patient testing 26
Before Patient Testing 26
The Twelve QSEs 26
Patient Preparation (Pre-Test Instructions) 27
Withholding Medications 27
Smoking Cessation 28
Other Patient Preparation Issues 28
Anthropometric Measurements 29
Physical Assessment 29
Pulmonary History 32
Test performance and sequence 32
Technologist-Driven Protocols 33
Patient Instruction 34
Summary 35
Case study 35
General References 37
Indications for Pulmonary Function Testing 37
Patterns of Impaired Pulmonary Function 38
Preliminaries to Patient Testing 38
Chapter 2: Spirometry 39
Vital capacity 40
Description 40
Technique 41
Significance and Pathophysiology 41
Forced vital capacity, forced expiratory volume, and forced expiratory flow 43
Description 43
Technique 44
Acceptability and Repeatability for Spirometry Results 48
Significance and Pathophysiology 49
Forced Vital Capacity 49
Forced Expiratory Volume 51
Forced Expiratory Volume Ratio 52
Forced Expiratory Flow 25%–75% 53
Flow-volume curve 54
Description 54
Technique 55
Significance and Pathophysiology 56
Flow-Volume Loops in Small Airway Obstruction 59
Flow-Volume Loops in Large Airway Obstruction 59
Flow-Volume Loops in Restrictive Disease 60
Peak expiratory flow 63
Description 63
Technique 63
Significance and Pathophysiology 64
Maximum voluntary ventilation 65
Description 65
Technique 65
Significance and Pathophysiology 66
Before- and after-bronchodilator studies 67
Description 67
Technique 67
Significance and Pathophysiology 69
Summary 70
Case studies 70
Entry-level 75
Advanced 77
General References 77
Spirometry 77
Peak Expiratory Flow 78
Before- and After-Bronchodilator Studies 78
Flow-Volume Curves 79
Standards and Guidelines 79
Chapter 3: Diffusing Capacity Tests 80
Carbon monoxide diffusing capacity 81
Description 81
Techniques 81
Single Breath-Hold Technique (Modified Krogh’s Technique) 82
Rebreathing Technique 89
Slow Exhalation Single-Breath Intrabreath Method 89
Membrane Diffusion Coefficient and Capillary Blood Volume 90
Significance and Pathophysiology 90
Summary 97
Case studies 97
Entry-level 101
Advanced 102
Selected bibliography 102
General References 102
Dlcosb 103
Dlcorb 103
Dlcoib 103
Standards and Guidelines 103
Chapter 4: Lung Volumes, Airway Resistance, and Gas Distribution Tests 104
Lung volumes: functional residual capacity, residual volume, total lung capacity, and residual volume/total lung capacity ... 105
Description 105
Technique 105
Open-Circuit, Multiple-Breath Nitrogen Washout 105
Closed-Circuit, Multiple-Breath Helium Dilution 109
Correcting for the “Switch-In” Error 111
Additional Comments on FRC by Gas Dilution Techniques 111
Body Plethysmography 112
Additional Comments on FRC by Plethysmography 116
Total Lung Capacity and Residual Volume/Total Lung Capacity Ratio 117
Significance and Pathophysiology 117
Airway resistance and conductance 120
Description 120
Technique 120
Significance and Pathophysiology 123
Gas distribution tests: single-breath nitrogen washout, closing volume, and closing capacity 125
Description 125
Technique 125
Significance and Pathophysiology 126
Δ%N2 750–1250 126
Slope of Phase III 126
Closing Volume and Closing Capacity 127
Multiple Breath nitrogen washout, lung clearance index, and phase III slope analysis 128
Description 128
Technique 128
Significance and Pathophysiology 128
Summary 128
Case studies 129
Entry-level 135
General References 137
Spirometry and Lung Volumes 137
Thoracic Gas Volume 137
Airway Resistance 137
Gas Dilution Lung Volumes 137
Gas Distribution 138
Standards and Guidelines 138
Chapter 5: Ventilation and Ventilatory Control Tests 139
Tidal volume, rate, and minute ventilation 140
Description 140
Technique 140
Significance and Pathophysiology 141
Respiratory dead space and alveolar ventilation 142
Description 142
Technique 143
Dead Space 143
Alveolar Ventilation 143
Significance and Pathophysiology 144
Ventilatory response tests for carbon dioxide and oxygen 145
Description 145
Technique 145
Significance and Pathophysiology 147
High-altitude simulation test 149
Description 149
Technique 149
Significance and Pathophysiology 151
Summary 152
Case studies 153
Entry-level 156
Advanced 156
General References 157
Ventilation 157
Control of Ventilation 157
High-Altitude Simulation Test (or Hypoxic Inhalation Test) 158
Chapter 6: Blood Gases and Related Tests 159
Chapter 7: Cardiopulmonary Exercise Testing and Field Tests 190
Field tests 192
Six-minute walk test (6mwt) reference set 194
Exercise protocols 195
Exercise workload 196
Cardiovascular monitors during exercise 200
Heart Rate and Electrocardiogram 200
Blood Pressure 203
Safety 205
Ventilation during exercise 206
Equipment Selection and Calibration 206
Minute Ventilation 208
Tidal Volume and Respiratory Rate 209
Flow-Volume Loop Analysis 212
Oxygen consumption, carbon dioxide production, and respiratory exchange ratio during exercise 213
Oxygen Consumption 213
Carbon Dioxide Production 215
Respiratory Exchange Ratio 215
Anaerobic or Ventilatory Threshold 216
Ventilatory Equivalent for Oxygen 217
Ventilatory Equivalent for Carbon Dioxide 218
Oxygen Pulse 218
Exercise blood gases 219
Arterial Catheterization 219
Arterial Puncture 219
Pulse Oximetry 220
Arterial Oxygen Tension During Exercise 220
Arterial Carbon Dioxide Tension During Exercise 221
Acid-Base Status During Exercise 222
Exercise Variables Calculated from Blood Gases 222
Cardiac output during exercise 223
Noninvasive Cardiac Output Techniques 223
Direct Fick Method 224
Thermodilution Method 224
Cardiac Output During Exercise 224
Symptoms Scales 225
Quality of Test 226
Interpretation Strategies 226
Summary 227
Case studies 228
Entry-level 240
Advanced 240
General References 242
Six-Minute Walk Test 242
Cardiovascular Monitoring During Exercise 242
Ventilation, Gas Exchange, and Blood Gases 242
Standards and Guidelines 242
Chapter 8: Pediatric Pulmonary Function Testing 244
Infant, toddler, and preschool pulmonary function testing 246
Purpose of Pulmonary Function Tests for Infants and Toddlers 246
Performance of Pulmonary Function Testing in Infants and Toddlers 247
Sedation as an Important Consideration 247
When Children Are Too Old for Infant-Style Testing and Too Young for Standard Testing 248
Lung Volume Measurement 248
Passive Tidal Techniques to Measure Respiratory Mechanics 250
Passive Tidal Loops 250
Passive Compliance, Resistance, and Time Constants 250
Thoracoabdominal Motion Analysis 252
Additional Passive Techniques Available to Measure in the Preschool Child 255
Impulse Oscillometry 255
Interrupter Technique (Rint) 256
Exhaled Nitric Oxide and Nasal Nitric Oxide 258
Forced Flow Techniques for Infants, Toddlers, and Preschool Children 259
Partial Expiratory Flow-Volume Curves 259
Forced Flows from Raised Lung Volume 261
Forced Deflation Technique 262
Spirometry 263
Age Considerations for Children Performing Spirometry 263
Ensuring Maximal Effort on the Part of the Child 264
Importance of Effort 267
Length of Exhalation for a Child During an FVC Maneuver 269
Reliability of FEF25%–75% in Children 271
Parameters of Inspiratory Forced Flow Helpful in Pediatrics 271
Role of Vocal Cord Dysfunction 272
VCD Combined with Intrathoracic Airflow Obstruction 274
Nonrepeatability in the Expiratory Maneuver 275
Airway Malacia 275
Diffusion capacity 276
Other Measured and Clinically Followed Parameters of Pulmonary Function in Pediatrics 278
Maximal Respiratory Pressures 278
Maximal Voluntary Ventilation 281
Arterial Blood Gases 281
Lung volumes 281
First Step 282
Important Plethysmographic Parameters 282
Role of Measurement of Airway Resistance 283
Bronchoprovocation challenges 283
Pulmonary Exercise Stress Testing 285
Exhaled nitric oxide standards for testing 287
Variability in Reference Sets and Predicted Values for Pediatrics 288
What the future holds for pediatric pulmonary function laboratories 290
Summary 291
Case studies 291
General References 300
Spirometry 300
Predicted Values and Reference Equations 300
Vocal Cord Dysfunction and Obstructing Upper Airway Lesions 301
Exercise Stress Testing 301
Pulmonary Function Testing in Infants and Very Young Children 301
Oscillometry and Nitric Oxide 302
Standards and Guidelines 303
Chapter 9: Bronchoprovocation Challenge Testing 304
Bronchoprovocation challenge testing 305
Methacholine Challenge 306
Five-Breath Dosimeter Method 310
2-Minute Tidal Breathing Method 310
Histamine Challenge 314
Mannitol Challenge 315
Exercise Challenge 317
Eucapnic Voluntary Hyperventilation 320
Summary 323
Case studies 323
Entry-level 326
Advanced 327
Bronchial Challenge 328
Guidelines and Standards 328
Chapter 10: Specialized Test Regimens 329
Respiratory muscle strength testing 330
Description 330
Technique 330
Significance and Pathophysiology 332
Exhaled nitric oxide 333
Description 333
Techniques 334
Online FeNO in Adults 334
Offline FeNO in Adults 335
Nasal Nitric Oxide 336
Significance and Pathophysiology 336
Forced oscillation technique 338
Preoperative pulmonary function testing 341
Spirometry 342
Bronchodilator Studies 342
Blood Gas Analysis 342
Exercise Testing 342
Diffusing Capacity (Dlco) 342
Perfusion and Scans 342
Pulmonary Artery Occlusion Pressure 343
Pulmonary function testing for social security disability 343
Forced Vital Capacity and Forced Expiratory Volume 344
Diffusing Capacity 345
Arterial Blood Gases 346
Exercise Testing 346
Metabolic measurements: indirect calorimetry 347
Description 347
Techniques 347
Open-Circuit Calorimetry 347
Closed-Circuit Calorimetry 348
Performing Metabolic Measurements 348
Metabolic Calculations 350
Significance and Pathophysiology 352
Summary 354
Case studies 354
Entry-level 359
Advanced 359
Respiratory Muscle Strength Testing 360
Exhaled Nitric Oxide 360
Forced Oscillation Technique 360
Preoperative Pulmonary Function Testing 361
Respiratory Impairment for Disability 361
Metabolic Measurements: Indirect Calorimetry 361
Guidelines and Standards 362
Chapter 11: Pulmonary Function Testing Equipment 363
Volume-displacement spirometers 364
Water-Seal Spirometers 364
Dry Rolling Seal Spirometers 367
Bellows-Type Spirometers 368
Flow-sensing spirometers 369
Turbines 370
Pressure Differential Flow Sensors 371
Heated-Wire Flow Sensors 373
Pitot Tube Flow Sensors 374
Ultrasonic Flow Sensors 374
Flow Sensor Summary 375
Portable (Office) Spirometers 376
Peak flowmeters 379
Body plethysmographs 380
Pressure Plethysmographs 380
Flow Plethysmographs 380
Breathing valves 384
Free Breathing and Demand Valves 384
Directional Valves 385
Gas-Sampling Valves 386
Pulmonary gas analyzers 387
Oxygen Analyzers 387
Polarographic Electrodes 387
Zirconium Fuel Cells 388
Infrared Absorption (CO2, CO) Analyzers 388
Emission Spectroscopy Analyzers 390
Thermal Conductivity Analyzers 391
Gas Chromatography 392
Chemoluminescence Analyzers 393
Gas-Conditioning Devices 394
Blood gas analyzers, oximeters, and related devices 395
pH Electrodes 395
Pco2 Electrodes 396
Po2 Electrodes 398
Laboratory Analyzers 399
Point-of-Care Analyzers 400
Transcutaneous Po2 and Pco2 Electrodes 400
Spectrophotometric Oximeters 401
Pulse Oximeter 402
Reflective Spectrophotometers 405
Computers for pulmonary function testing 406
Data Acquisition and Instrument Control 407
Pulmonary Function Data Storage and Programs 409
Temporary Storage or No Data Storage 409
Permanent Individual Patient Data Files 409
Database Storage 409
Summary 410
Self-assessment questions 411
Entry-level 411
Advanced 411
Spirometers 412
Peak Flowmeters 413
Plethysmographs 413
Gas Analyzers 413
Blood Gas Electrodes, Oximeters, and Related Devices 414
Computers 414
Chapter 12: Quality Systems in the Pulmonary Function Laboratory 415
Quality manual 417
Quality system essentials 418
Organization 418
Customer Focus 418
Facilities and Safety 418
Pulmonary Function Tests 419
Blood Gases 420
Personnel 422
Purchasing and Inventory 424
Equipment 424
Installation, Validation, and Verification 425
Equipment Maintenance 425
Process Management 426
Control Methods: Mechanical and Biologic 426
Quality Control Tools and Materials 426
Syringes 426
Sine-Wave Rotary Pumps 427
Computerized Syringes 428
Computer-Driven Syringes 428
Explosive Decompression Devices 428
Dlco Simulator 428
Quality Control Concepts 429
Spirometry Calibration and Mechanical Quality Control 430
Gas Analyzers and Dlco Systems 434
Physiologic Range 434
Sampling Conditions 434
Two-Point Calibration 435
Multiple-Point (Linearity) Calibration 435
Dlco Systems 436
Body Plethysmographs 438
Mouth Pressure Transducer 438
Box Pressure Transducer 439
Flow Transducer 439
Biologic Controls 440
Calibration and Quality Control of Blood Gas Analyzers 442
Tonometry 445
Commercially Prepared Controls 445
Documents and Records 449
Information Management 449
Nonconforming Event Management 450
Assessments 450
Continual Improvement 451
Technologist’s Feedback 454
Path of workflow 454
Pretest Process 454
Testing 455
Test Method Selection 455
Test Performance 456
Using Criteria for Acceptability/Repeatability 456
Examine Printed Tracings or Displayed Graphics Whenever Available 456
Look at Numeric Data 457
Evaluate Key Indicators 457
Posttesting 459
Summary 459
Case studies 460
Entry-level 463
Advanced 463
General References 464
Standards and Guidelines 464
Calibration and Quality Control 465
Chapter 13: Reference Values and Interpretation Strategies 466
Selecting and using reference values 467
Spirometry 468
Lung Volumes 468
Diffusing Capacity 468
Establishing what is abnormal 469
Pulmonary function testing interpretation, “bringing it all together” 474
Interpretation algorithm 474
Quality Review and “The Graph” 474
The Ratio” 475
Gas Exchange 476
Bronchodilator Response 477
Grading Severity and Assessing Change in Lung Function 477
Summary 478
Case studies 478
Entry-level 485
Advanced 485
General 486
Spirometry 486
Lung Volumes 486
Diffusing Capacity 486
Appendix A: Answers to Self-Assessment Questions 488
Chapter 1, Indications for pulmonary function testing 488
Chapter 2, Spirometry 488
Chapter 3, Diffusing capacity tests 488
Chapter 4, Lung volumes, airway resistance, and gas distribution tests 488
Chapter 5, Ventilation and ventilatory control tests 488
Chapter 6, Blood gases and related tests 488
Chapter 7, Cardiopulmonary exercise testing and field tests 488
Chapter 8, Pediatric pulmonary function testing 489
Chapter 9, Bronchoprovocation CHALLENGE testing 489
Chapter 10, Specialized test regimens 489
Chapter 11, Pulmonary function testing equipment 489
Chapter 12, Quality systems in the pulmonary function laboratory 489
Chapter 13, Reference values and interpretation strategies 489
Glossary 490
Index 508
Inside Back Cover ES3