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Book Details
Abstract
The topics covered in this volume describe contrasting types of Electron Paramagnetic Resonance (EPR) application, including inorganic paramagnetic systems, spin-labeling in highly dynamic systems such as RNAs and IDPs and applications of nitroxides in host:guest chemistry. EPR applications remain very significant in modern science and this volume compiles critical coverage of developments in the recent literature by a hand-picked group of researchers at the cutting-edge of the field. Providing a snap shot of the area, this book is a useful addition to any library supporting this research.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Cover | Cover | ||
| Contents | vii | ||
| Preface | v | ||
| Tuning the properties of nitroxide spin labels for use in electron paramagnetic resonance spectroscopy through chemical modification of the nitroxide framework | 1 | ||
| 1 Introduction | 1 | ||
| 2 The nitroxide spin label as a probe in EPR spectroscopy | 2 | ||
| 3 Synthetic routes to nitroxide spin labels | 8 | ||
| 4 Recent advances in applications of spin labels | 19 | ||
| 5 Summary | 26 | ||
| References | 26 | ||
| Trityl radicals as spin labels | 35 | ||
| 1 Introduction | 35 | ||
| 2 TAM radicals: structure and properties | 36 | ||
| 3 Synthesis of TAM radicals and TAM labeling of proteins and nucleic acids | 39 | ||
| 4 Electron spin relaxation of TAM radicals | 44 | ||
| 5 Peculiarities of PD EPR approaches to distance measurement using TAM spin labels | 46 | ||
| 6 Distance measurements at physiologically relevant temperatures | 50 | ||
| 7 Conclusion | 56 | ||
| Acknowledgments | 56 | ||
| References | 57 | ||
| Molecules as electron spin qubits | 61 | ||
| 1 Introduction | 61 | ||
| 2 Quantum hardware | 62 | ||
| 3 Experimental methods | 64 | ||
| 4 Organic molecular qubits | 66 | ||
| 5 Inorganic molecular qubits | 69 | ||
| 6 Outlook | 92 | ||
| Acknowledgments | 92 | ||
| References | 92 | ||
| Status and perspectives of a virtual multifrequency spectrometer for ESR | 98 | ||
| 1 Introduction | 98 | ||
| 2 Interpretative models for magnetic spectroscopies | 103 | ||
| 3 Spin Hamiltonian | 106 | ||
| 4 Stochastic diffusion operator, relaxation | 122 | ||
| 5 Stochastic ab initio spectra simulation of CW-ESR | 134 | ||
| 6 Towards a multi-body ESR: novel computational techniques | 140 | ||
| 7 Conclusions | 150 | ||
| Acknowledgments | 151 | ||
| References | 151 | ||
| Application of site-directed spin labelling for studying conformational changes in the catalytic cycle of G proteins activated by dimerization | 157 | ||
| 1 Introduction | 157 | ||
| 2 Site-directed spin labelling and EPR spectroscopy | 163 | ||
| 3 Conformational changes in the catalytic cycle of GADs | 165 | ||
| 4 Discussion | 174 | ||
| Acknowledgments | 177 | ||
| References | 177 | ||
| Nitroxides in host–guest chemistry: 2010–2016 | 180 | ||
| 1 Introduction | 180 | ||
| 2 Cyclodextrins as hosts | 181 | ||
| 3 Cucurbituril as a host | 195 | ||
| 4 Miscellaneous | 211 | ||
| 5 Conclusion | 231 | ||
| Acknowledgments | 231 | ||
| References | 231 |