Additional Information
Book Details
Abstract
Dermatology, Allergy, Immunity & Infection is a new e-book in a collection of subject-themed e-books containing relevant key articles from Paediatrics & Child Health. The e-books provide a perfect source of revision for post-graduate exams in paediatrics and portfolio material for life-long learning.
As well as mapping to the requirements of post-graduate training in paediatrics, these e-books also enable anyone with a short-term interest in a specific area to buy individual articles at a price-point that will give affordable access to all readers (from medical students to GPs and practitioners in related areas). The quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move.
About the journal
The parent journal (http://www.paediatricsandchildhealthjournal.co.uk/) is a rolling, continuously updated review of clinical medicine over a 4-year cycle covering all the important topics for post-graduate exams in paediatrics. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. A trainee representative on the Board ensures relevance and accessibility for exam candidates.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Dermatology, Allergy, Immunity and Infection: Prepare for the MRCPCH | Fm-1 | ||
| Copyright Page | Fm-2 | ||
| PREFACE | Fm-4 | ||
| Table of Contents | Fm-5 | ||
| Section 1: Dermatology | 1 | ||
| Assessing skin disease in children | 1 | ||
| Introduction | 1 | ||
| History | 1 | ||
| Associated symptoms | 1 | ||
| Timing | 1 | ||
| Previous treatments and efficacy | 1 | ||
| Family history | 1 | ||
| General health | 1 | ||
| Examination | 1 | ||
| Pattern, distribution and morphology | 1 | ||
| Investigations | 2 | ||
| Chronic skin disease | 2 | ||
| Hypo and depigmented conditions | 3 | ||
| Neonatal conditions | 4 | ||
| Common, benign neonatal conditions | 4 | ||
| Vascular lesions | 4 | ||
| Summary | 5 | ||
| FURTHER READING | 5 | ||
| The management of eczema in children | 6 | ||
| Introduction | 6 | ||
| Aetiology | 6 | ||
| Treatments | 8 | ||
| Complications | 10 | ||
| FURTHER READING | 11 | ||
| Management of infantile haemangioma | 12 | ||
| Introduction | 12 | ||
| Subtypes | 12 | ||
| Multiple haemangiomatosis | 12 | ||
| Extra-cutaneous haemangioma | 12 | ||
| Assessment of haemangioma | 12 | ||
| Investigation of IH | 14 | ||
| Treatment of haemangioma | 14 | ||
| Conclusion | 17 | ||
| FURTHER READING | 17 | ||
| Hair loss in infancy and childhood | 18 | ||
| Introduction | 18 | ||
| Normal hair growth | 18 | ||
| Evaluation of a child with hair loss | 18 | ||
| Hair disorders in infancy | 18 | ||
| My child’s hair won’t grow | 20 | ||
| My child has unruly hair | 21 | ||
| My child’s hair keeps coming out | 21 | ||
| My child has developed new patches of hair loss | 22 | ||
| Conclusion | 23 | ||
| FURTHER READING | 23 | ||
| Infections and infestations of the skin | 24 | ||
| Bacterial infections | 24 | ||
| Viral infections | 25 | ||
| Fungal infections | 27 | ||
| Infestations | 28 | ||
| FURTHER READING | 28 | ||
| Management of paediatric dermatological emergencies | 30 | ||
| Erythroderma | 30 | ||
| Collodian baby | 30 | ||
| Harlequin ichthyosis | 30 | ||
| Acute erythrodermic psoriasis (Figure 1) | 30 | ||
| Staphylococcal scalded skin syndrome (SSSS) (Figure 2) | 31 | ||
| Toxic shock syndrome (TSS) | 31 | ||
| Eczema herpeticum (Figure 3a and b) | 32 | ||
| Adverse drug reactions (ADRs) | 32 | ||
| StevenseJohnson syndrome (SJS) | 32 | ||
| Toxic epidermal necrolysis (TEN) | 33 | ||
| DRESS syndrome | 33 | ||
| Purpura fulminans | 34 | ||
| Infantile haemangiomas (Figure 4) | 34 | ||
| Epidermolysis bullosa | 34 | ||
| Conclusion | 34 | ||
| FURTHER READING | 34 | ||
| Section 2: Allergy | 36 | ||
| Paediatric allergy in review | 36 | ||
| Introduction | 36 | ||
| Prevalence | 36 | ||
| Risk factors | 36 | ||
| Diet and lifestyle | 37 | ||
| Pollutants | 37 | ||
| Immunological paradigms of sensitization and disease | 38 | ||
| The allergic march of childhood | 38 | ||
| Prospects for the future: intervention and prevention | 39 | ||
| FURTHER READING | 40 | ||
| The prevention and management of anaphylaxis | 41 | ||
| Introduction | 41 | ||
| What is anaphylaxis? | 41 | ||
| Management of anaphylaxis | 43 | ||
| Prevention of anaphylaxis | 46 | ||
| Conclusion | 47 | ||
| FURTHER READING | 47 | ||
| Diagnosis and management of food allergy | 49 | ||
| Introduction | 49 | ||
| Diagnosing food allergy | 50 | ||
| Managing food allergy | 55 | ||
| Follow up | 57 | ||
| Summary | 57 | ||
| FURTHER READING | 57 | ||
| Recurrent urticaria | 58 | ||
| Prevalence | 58 | ||
| Definition | 58 | ||
| Mechanism | 58 | ||
| Diagnosis of urticaria | 58 | ||
| Classification of urticaria subtypes | 59 | ||
| Assessment of disease activity | 61 | ||
| Quality of life | 61 | ||
| Principles of treatment of urticaria | 62 | ||
| Follow-up of chronic urticaria | 62 | ||
| FURTHER READING | 62 | ||
| WEBSITE | 63 | ||
| Allergic rhinitis — an overview of a common disease | 64 | ||
| Introduction | 64 | ||
| AR impacts on quality of life | 64 | ||
| Definition | 64 | ||
| Presentation | 64 | ||
| Differential diagnosis and co-morbidities | 65 | ||
| Allergic rhinitis and asthma | 65 | ||
| Differential diagnosis | 66 | ||
| Classification | 66 | ||
| Investigations | 66 | ||
| Therapy | 66 | ||
| Allergen specific immunotherapy (SIT) | 68 | ||
| Conclusion | 68 | ||
| FURTHER READING | 68 | ||
| Oral immunotherapy for the treatment of food allergy | 70 | ||
| Introduction | 70 | ||
| Immunological mechanisms of tolerance | 70 | ||
| Allergen specific immunotherapy for food allergy | 70 | ||
| Summary and challenges ahead | 74 | ||
| Role of funding source | 75 | ||
| FURTHER READING | 75 | ||
| Section 3: Infection and Immunity | 76 | ||
| Periodic fevers and autoinflammatory conditions | 76 | ||
| Introduction | 76 | ||
| Epidemiology | 76 | ||
| Pathogenesis | 76 | ||
| Assessment of possible AIS in a child with recurrent fever | 76 | ||
| Neonatal and infantile fevers | 77 | ||
| Childhood periodic fevers | 78 | ||
| Principles of treatment | 80 | ||
| Conclusion | 80 | ||
| FURTHER READING | 80 | ||
| Treating malaria in the UK | 81 | ||
| Background | 81 | ||
| Pathogenesis | 81 | ||
| Clinical presentation | 81 | ||
| Diagnosis | 82 | ||
| Treatment | 82 | ||
| FURTHER READING | 84 | ||
| Infection following haematopoietic stem cell transplantation | 85 | ||
| Introduction | 85 | ||
| Haematopoietic stem cell transplant procedure | 85 | ||
| Preventative measures | 85 | ||
| Assessment and treatment of pre-existing infection | 86 | ||
| Infection through the transplant period | 86 | ||
| Routine viral surveillance and treatment | 86 | ||
| Preservation of immune function through transplantation | 88 | ||
| Immunomodulatory treatments for GvHD | 89 | ||
| Future perspectives | 89 | ||
| Conclusion | 90 | ||
| FURTHER READING | 90 | ||
| Treating invasive Group A Streptococcal infections | 91 | ||
| Introduction | 91 | ||
| The bacterium | 91 | ||
| Epidemiology | 91 | ||
| Emm type and disease severity | 92 | ||
| Transmission | 92 | ||
| Risk factors for disease | 92 | ||
| Pathogenesis | 93 | ||
| Superantigens | 93 | ||
| Presentation | 94 | ||
| Diagnosis | 94 | ||
| Investigations | 94 | ||
| Management | 95 | ||
| Challenges in treatment | 95 | ||
| Sources of funding | 96 | ||
| FURTHER READING | 96 | ||
| Central nervous system herpesvirus infections | 97 | ||
| Introduction | 97 | ||
| Herpes simplex virus (HSV) | 97 | ||
| Sporadic HSV encephalitis (HSE) | 97 | ||
| Neonatal HSV CNS disease | 99 | ||
| Varicella-Zoster virus (VZV) | 99 | ||
| EpsteineBarr virus (EBV) | 100 | ||
| Cytomegalovirus (CMV) | 100 | ||
| HHV-6 | 101 | ||
| HHV-7 | 102 | ||
| Conclusions | 102 | ||
| FURTHER READING | 102 | ||
| Congenital cytomegalovirus infection | 104 | ||
| Introduction | 104 | ||
| Clinical manifestations | 105 | ||
| Diagnosis | 106 | ||
| Management | 107 | ||
| Long-term follow-up | 107 | ||
| Prevention | 108 | ||
| FURTHER READING | 108 | ||
| The normal function of the immune system in a clinical context | 109 | ||
| Introduction | 109 | ||
| Overview — the integrated immune response | 109 | ||
| First lines of defence | 109 | ||
| Complement | 109 | ||
| Cellular responses of the innate immune system | 110 | ||
| Adaptive immunity | 112 | ||
| Immunological memory | 115 | ||
| The spleen | 115 | ||
| Mucosal immune system | 115 | ||
| Conclusion | 116 | ||
| FURTHER READING | 116 | ||
| Current developments and trends in childhood immunization | 117 | ||
| Introduction | 117 | ||
| Live attenuated intranasal vaccine against influenza | 118 | ||
| Rotavirus gastroenteritis | 119 | ||
| Pertussis | 120 | ||
| Meningococcal vaccines | 120 | ||
| Conclusions | 121 | ||
| FURTHER READING | 122 | ||
| An update on HIV in children | 123 | ||
| Introduction | 123 | ||
| Pathways of infection and prevention | 123 | ||
| Financial disclosure statement | 127 | ||
| FURTHER READING | 128 | ||
| Advances in management of primary immunodeficiency | 129 | ||
| Diagnosis | 129 | ||
| Newborn screening | 130 | ||
| Management | 130 | ||
| FURTHER READING | 133 | ||
| Adverse events following immunizations: fact and fiction | 135 | ||
| Introduction | 135 | ||
| Vaccine registration | 135 | ||
| Definitions of adverse events following immunization (AEFI) | 135 | ||
| Fiction | 136 | ||
| Autoimmune diseases | 136 | ||
| MMR and autism | 137 | ||
| Background rates of AEFI | 137 | ||
| No fault compensation | 137 | ||
| Summary | 137 | ||
| FURTHER READING | 137 |