Additional Information
Book Details
Abstract
Readership: General public, scientists, policy makers, health care workers, and politicians.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Contents | xxiii | ||
| About the Author | ix | ||
| Preface | xi | ||
| 1. Origins of the Epidemic | 1 | ||
| The Wee Beastie | 7 | ||
| The Molecular Battlefield | 10 | ||
| References | 27 | ||
| 2. How Well Do We Understand the 2014 Ebolavirus ? | 31 | ||
| Phylogenies Are Not Data | 40 | ||
| Evolution Caught Red-handed | 49 | ||
| References | 51 | ||
| 3. Ways in Which Ebola Guinea May Differ from Past Outbreaks: Evolution of Viral Phenotypes | 53 | ||
| “Going Airborne” | 53 | ||
| Shifting Other Routes of Transmission | 55 | ||
| Replicating More Slowly | 56 | ||
| Asymptomatic Transmission | 57 | ||
| Change in Host Tissue Virulence Patterns, and Primary Mode of Death | 61 | ||
| References | 63 | ||
| 4. Biological Knowledge and Ebola Policy | 65 | ||
| Indirect Transmissions | 69 | ||
| MRSA Indirect Transmission Analogy | 70 | ||
| Doctors and Nurses, The First Line of Defense | 74 | ||
| Reverse White Coat Syndrome? | 80 | ||
| References | 90 | ||
| 5. “How Cruel is That?” | 93 | ||
| “How Cruel is That?” | 94 | ||
| References | 113 | ||
| 6. With Blinded Eyes | 115 | ||
| References | 125 | ||
| 7. Are We Asking the Right Questions and Solving All the Right Problem(s)? | 127 | ||
| “We are Prepared to Handle an Ebola Outbreak in the United States” | 129 | ||
| Early Diagnosis to Protect the Public Health | 131 | ||
| References | 133 | ||
| 8. Evolution is Real: Deadly Consequences of Dogma | 137 | ||
| References | 143 | ||
| 9. Promising Treatments | 145 | ||
| Vaccine Development | 146 | ||
| Pharmaceutical Hopefuls | 149 | ||
| Managing the Spread via “Ebola-Free Zones” | 154 | ||
| Treating the Reservoir Hosts | 154 | ||
| Hemopurification (Dialysis) | 155 | ||
| References | 156 | ||
| 10. Policy Analysis | 159 | ||
| Probabilities and Modes of Transmission | 164 | ||
| Self-Monitoring, Self-Quarantine, or Mandatory Quarantine? | 170 | ||
| No Mutations? | 175 | ||
| Can Humans get Ebola from Dogs? | 176 | ||
| Policy Assessment | 177 | ||
| Conclusions | 177 | ||
| Recommendations | 178 | ||
| References | 179 | ||
| 11. A Rational Analysis of Irrational Decisions, or Don’t Fear the Reaper | 183 | ||
| Don’t Fear the Reaper | 189 | ||
| Fear and Government Policy | 192 | ||
| References | 195 | ||
| Appendix 1 | 197 | ||
| (a) Penalties for persons violating quarantine laws | 197 | ||
| Appendix 2: Ebola Virus Disease (EVD) Clinical Outcomes Data Form | 199 | ||
| Epilogue | 203 | ||
| February, 2015 | 205 | ||
| March, 2015 | 211 | ||
| Treating Vascular Leakage | 215 | ||
| References | 216 | ||
| Index | 219 |