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Current Therapy in Colon and Rectal Surgery E-Book

Current Therapy in Colon and Rectal Surgery E-Book

Victor W. Fazio | James M. Church | Conor P Delaney | Ravi P Kiran

(2016)

Additional Information

Book Details

Abstract

For more than 25 years, Current Therapy in Colon and Rectal Surgery has been the go-to resource for preparing for the American Board of Surgery certification exam. Following in this tradition, the 3rd Edition offers a comprehensive, contemporary summary of treatment options for colorectal diseases, with a focus on practical clinical science and applications. In a single, portable volume, you’ll find complete coverage of new diagnostic modalities, medical therapeutics, and surgical treatment options, including minimally invasive surgery. Easy to read and digest, it provides a quick consultation with experts on the essentials of colon and rectal surgery.

  • Consult this title for a quick overview before you enter the OR, and use it as a review tool for board certification and recertification.
  • Nearly 100 succinct chapters, just 3 or 4 pages each, written by leading experts in colorectal surgery.
  • Five chapters devoted exclusively to different aspects of rectal cancer.
  • Other key topics include minimally invasive surgery, reparative surgery, maturing outcomes, and managing surgical risk.
  • New chapters focus on hot topics such as intestinal transplants, enhanced recovery programs, and the management of peristomal hernias.
  • Updated information on the molecular biology of colorectal cancer and its implications for therapy.

Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC ES1
Current therapy in colon and rectal surgery i
Copyright ii
Dedication iii
Contributors v
Preface to the third edition xiii
Acknowledgments xiv
Contents xv
1 - ANAL AND PERIANAL REGION 1
1 - Anatomy and Physiology of the Colon, Rectum, and Anal Canal* 3
ANATOMY OF THE COLON AND RECTUM 3
Colon 3
Course and Peritoneal Coverings 3
Rectum 3
Peritoneal Relations and Fascial Attachments 3
ARTERIAL SUPPLY 4
Superior Mesenteric Artery 4
Inferior Mesenteric Artery 4
Collateral Circulation 5
VENOUS DRAINAGE 5
Superior Mesenteric Vein 5
Inferior Mesenteric Vein 5
LYMPHATIC DRAINAGE 5
INNERVATION 5
COLON AND RECTUM PHYSIOLOGY 6
Colonic Physiology 6
Absorption and Secretion 6
Digestion 6
Propulsion and Storage 6
ANAL CANAL ANATOMY 7
Lining 7
Muscles of the Anorectal Region 8
Perineal Body 8
Pelvic Floor Muscles 8
Innervation of the Anus 8
Motor Innervation 8
Sensory Innervation 9
Arterial Supply of the Anus 9
Lymphatic Drainage of the Anus 9
Venous Drainage of the Anus 9
ANAL CANAL PHYSIOLOGY 9
Mechanisms of Continence 9
Defecation 9
Physiologic Testing 9
Anal Manometry 9
Defecography by Fluoroscopy or Magnetic Resonance Imaging 10
Balloon Expulsion Test 10
Saline Continence Test 10
Rectal Compliance 10
Electromyography 10
Nerve Stimulation Techniques 10
Suggested Reading 11
2 - Hemorrhoids 12
EXTERNAL HEMORRHOIDS 12
ANATOMY AND ETIOLOGY OF INTERNAL HEMORRHOIDS 12
CLINICAL EVALUATION 12
NONEXCISIONAL OPTIONS 13
Medical Management 13
Sclerotherapy 13
Energy-Based Destruction 13
Hemorrhoidal Ligation with Rubber Bands 13
EXCISIONAL HEMORRHOIDECTOMY 13
Instrumentation for Excisional Hemmorrhoidectomy 14
PROCEDURE FOR PROLAPSING HEMORRHOIDS (STAPLED HEMMORHOIDOPEXY) 14
DOPPLER-GUIDED HEMORRHOIDAL DEARTERIALIZATION 14
POSTOPERATIVE MANAGEMENT AFTER HEMORRHOID SURGERY 14
CONCLUSION 15
Suggested Reading 15
3 - Chronic Anal Fissure 16
INTRODUCTION 16
DIAGNOSIS 16
PATHOPHYSIOLOGY 16
High-Pressure Chronic Anal Fissure 16
Low- and Normal-Pressure Chronic Anal Fissure 16
MANAGEMENT 17
Topical Creams 17
Botulinum Toxin 17
Fissurectomy 17
Cutaneous Advancement Flap 18
Lateral Internal Sphincterotomy 18
Surgical Technique 18
Risk of Incontinence 18
Tailored Sphincterotomy 18
Treatment of Low/Normal Pressure Chronic Anal Fissure 18
SUMMARY: CHOICE OF TREATMENT 19
Suggested Reading 19
4 - Anorectal Abscess 21
SURGICAL ANATOMY 21
ETIOLOGY 21
NATURAL HISTORY OF THE DISEASE AND SPREAD PATHWAYS 21
CLINICAL FEATURES 21
Perianal Abscess 21
Ischiorectal Abscess 21
Intersphincteric Abscess 22
Supralevator Abscess 22
Deep Postanal Abscess 22
Submucosal Abscess 22
DIAGNOSIS 22
Treatment of Anorectal Abscesses 22
Large Abscesses 22
Searching for a Fistula 22
Ischiorectal Abscess 23
Intersphincteric Abscesses 23
Supralevator Abscess 23
Submucosal Abscess 23
Role of Antibiotics and Biopsy 23
Postoperative Care 23
Complications 23
RECURRENCE AND THE DEVELOPMENT OF FISTULA IN ANO 23
Suggested Reading 23
5 - Anal Fistula 24
INTRODUCTION 24
ETIOLOGY 24
CLASSIFICATION 24
PRESENTATION 24
DIAGNOSIS AND EVALUATION 24
Preparation and Examination 25
2 - RECTAL AND PARARECTAL REGION 91
19 - Fecal Incontinence 93
INTRODUCTION AND INCIDENCE 93
CAUSES 93
ASSESSMENT 93
TREATMENT 94
Medical Management 94
Biofeedback 94
Surgery 94
Anal Sphincter Repair (Sphincteroplasty) 94
Postanal Repair 95
Anal Encirclement 95
Muscle Transposition 95
Sacral Nerve Stimulation 95
Posterior Tibial Nerve Stimulation 96
Continence Enemas 96
Stem Cells, Bulking Agents, and Other Techniques 96
Fecal Diversion 96
CONCLUSIONS 96
Suggested Readings 97
20 - Rectal Stricture: Etiology and Management 98
DEFINITION 98
PRESENTATION AND DIAGNOSIS 98
ETIOLOGY 98
BENIGN RECTAL STRICTURES 98
Rectal Strictures Related to Inflammatory Bowel Disease 98
MALIGNANT RECTAL STRICTURES 100
SUMMARY 100
Suggested Readings 100
21 - Management of Fecal Impaction 102
INTRODUCTION 102
ETIOPATHOLOGY 102
Presentation 102
DIAGNOSIS 103
TREATMENT 103
Medical Treatment 103
Digital Evacuation 103
Enemas and Colonic Lavage 103
Oral Solutions 104
Stool Softeners 104
Laxatives 105
Endoscopic Disimpaction 105
SURGERY 105
Acute 105
Chronic 105
PREVENTION 105
CONCLUSION 105
Suggested Reading 105
22 - Rectal Prolapse 107
INTRODUCTION 107
PATHOPHYSIOLOGY 107
CLINICAL FEATURES 107
PREOPERATIVE CONSIDERATIONS 107
SURGICAL OPTIONS 108
Perineal Repairs 108
Abdominal Procedures 108
Recommendations 109
Problems 109
MANAGEMENT OF RECURRENT PROLAPSE 109
Suggested Reading 109
23 - Solitary Rectal Ulcer Syndrome 111
INTRODUCTION 111
CAUSE 111
PATHOPHYSIOLOGY 111
CLINICAL FEATURES 111
DIAGNOSIS 112
MANAGEMENT 112
Nonoperative Management 112
Surgery 113
CONCLUSIONS 113
Suggested Reading 113
24 - Rectocele 114
DEFINITION 114
CAUSES 114
SYMPTOMS 114
DIAGNOSIS 114
MANAGEMENT 115
SURGICAL TREATMENT 115
Transanal Repairs 115
Transvaginal Repairs 115
Transperineal Repairs 116
Comparison of Approaches 116
SUMMARY 116
Suggested Reading 117
25 - Rectal Foreign Bodies 118
EPIDEMIOLOGY 118
EVALUATION 118
CLASSIFICATION 118
American Association for the Surgery of Trauma Rectal Organ Injury Scale 118
Location of the Foreign Body 119
Intraperitoneal or Extraperitoneal 119
EXTRACTION 119
MANAGEMENT 119
POSTEXTRACTION CARE 120
Suggested Reading 120
26 - Diagnosis and Management of Sacral and Retrorectal Tumors 121
INTRODUCTION 121
ANATOMY OF THE RETRORECTAL SPACE 121
CLASSIFICATION SYSTEMS 121
CONGENITAL/DEVELOPMENTAL LESIONS 122
Germ Cell Tumors 122
Tailgut Cysts 123
Duplication Cysts 123
Anterior Sacral Meningocele 124
Chordoma 124
Osseous Tumors 125
Neurogenic Tumors 127
Nonosseous Mesenchymal Tumors 127
INFLAMMATORY LESIONS 127
METASTATIC LESIONS 127
DIAGNOSTIC APPROACHES TO SACRAL AND RETRORECTAL TUMORS 127
OPERATIVE APPROACHES 128
SUMMARY 130
Suggested Reading 130
27 - Management of Rectal Villous Tumors 132
INTRODUCTION 132
RECTAL ANATOMY AND PHYSIOLOGY 132
CLINICALLY SIGNIFICANT ASSOCIATIONS OF RECTAL FUNCTION 132
THERAPEUTIC OPTIONS RESULTING FROM THE LOCATION OF THE RECTUM 132
RECTAL VILLOUS TUMORS 132
ASSESSING THE LESION FOR CANCER 132
TREATMENT 132
Endoscopic Polypectomy 132
Transanal Excision 133
Transanal Endoscopic Microsurgery/Transanal Minimally Invasive Surgery 134
Delorme Procedure 134
Trans-sacral Resection 134
Anterior Resection 134
FOLLOW-UP 134
Suggested Reading 134
28 - Preoperative Evaluation of the Patient with Rectal Cancer: Staging and Strategy 135
INTRODUCTION 135
CLINICAL ASSESSMENT 135
History 135
Physical Examination 135
ENDOSCOPIC EVALUATION AND BIOPSY 135
PREOPERATIVE STAGING WITH IMAGING MODALITIES 136
Locoregional Evaluation 136
Tumor Stage and the Circumferential Resection Margin 136
Nodal Staging 137
Extramural Venous Invasion 138
Locoregional Imaging Synoptic Reports 138
Distant Metastatic Evaluation 138
Serum Tumor Markers 139
ROLE OF MULTIDISCIPLINARY CANCER CONFERENCES 139
Suggested Readings 140
29 - Cancer of the Rectum: Neoadjuvant Therapy 141
INTRODUCTION 141
RADIOTHERAPY TRIALS 141
ROLE OF CIRCUMFERENTIAL RESECTION MARGIN 141
MULTIMODALITY TREATMENT APPROACHES 141
RANDOMIZED TRIALS COMPARING NEOADJUVANT SHORT-COURSE RADIOTHERAPY WITH CHEMOTHERAPY–LONG-COURSE RADIOTHERAPY 142
RADIATION TREATMENT VOLUMES 142
RADIATION-RELATED TOXICITIES 142
OTHER PERIOPERATIVE RADIATION TREATMENT OPTIONS 142
Boosting the Dose 142
INTRAOPERATIVE RADIATION THERAPY 144
INTENSITY-MODULATED RADIATION THERAPY 144
HIGH-DOSE-RATE ENDORECTAL BRACHYTHERAPY 144
SUMMARY 144
Suggested Reading 144
30 - Cancer of the Rectum: Operative Management 146
INTRODUCTION 146
KEY ANATOMIC POINTS 146
PRESURGICAL PATIENT PREPARATION AND EVALUATION 146
PREOPERATIVE DECISION MAKING 147
Deciding Between an Open or Laparoscopic Approach 147
Should a Stapled or Hand-Sewn Restorative Procedure Be Performed? 147
SURGICAL PRINCIPLES 147
Total Mesorectal Excision 147
Ligation of the Inferior Mesenteric Artery 147
Distal Resection Margins 147
Choice of Anastomotic Configuration 147
Drainage 148
Diverting Stoma 148
KEY STEPS OF SURGICAL PROCEDURES 148
Low Anterior Resection 148
Positioning and Equipment 148
Trocar Placement 148
Exposure of the Operating Field 148
Identification of Inferior Mesenteric Vessels and Left Ureter 148
Division of the Vessels and Splenic Flexure Mobilization 148
Mobilization and Division of the Rectum 148
Exteriorization of the Specimen 149
Creation of the Anastomosis 149
Desufflation and Closure of Trocar Incisions 149
Abdominoperineal Resection 149
Closure of the Anal Opening 149
Mobilization of the Rectum 149
Proximal Division of the Left Colon 149
Perineal Dissection and Exteriorization 149
Closure of Pelvic Wound and Trocar Incisions and Creation of the Colostomy 149
PELVIC EXENTERATION 150
Surgical Approaches 150
Assessment Before Exenteration 150
Signs of Irresectability 150
Sacrectomy 150
Pelvic Sidewall Disease 150
Anterior Compartment/Urogenital Disease 150
Central Recurrence 150
Bladder Reconstruction 150
Perineal Reconstruction 150
OUTCOMES: SURVIVAL AND LOCAL RECURRENCE 150
Suggested Reading 151
31 - Local Treatment of Rectal Cancer 152
INTRODUCTION 152
PREOPERATIVE EVALUATION 152
INITIAL SELECTION 153
SURGICAL TECHNIQUE 153
Patient Preparation 153
Transanal Excision 153
Transanal Endoscopic Microsurgery/Transanal Endoscopic Operation 153
Transanal Minimally Invasive Surgery 154
MANAGEMENT OF THE SPECIMEN 154
FOLLOW-UP 154
RESULTS 154
Local Excision for T1N0 Rectal Cancer 154
Local Excision for T2N0 Rectal Cancer 154
Salvage Resection after Local Excision 155
ALTERNATIVE TO LOCAL EXCISION: ENDOCAVITARY CONTACT RADIATION 155
CONCLUSIONS: ALGORITHM FOR TREATMENT BY LOCAL EXCISION 156
32 - Locally Recurrent Rectal Cancer: Management and Follow-up 157
INTRODUCTION 157
NOMENCLATURE OF PELVIC RECURRENCE 157
CLINICAL EVALUATION FOR SUSPECTED PELVIC RECURRENCE 157
MANAGEMENT OF PELVIC RECURRENCE 158
Category I: Asymptomatic Local and Distant Recurrence 158
Category II: Symptomatic Local Recurrence in the Presence of Distant Disease 158
Category III: Unresectable, Isolated Local Recurrence 158
Category IV: Resectable Isolated Local Recurrence 158
Axial Recurrences 159
Anterior Recurrences 159
Posterior Recurrences 159
Lateral Recurrences 159
THE ROLE OF CHEMORADIATION FOR PELVIC RECURRENCE 159
PREOPERATIVE AND INTRAOPERATIVE CONSIDERATIONS 159
RECONSTRUCTION OPTIONS FOR PERINEAL DEFECTS 160
SUMMARY 160
Suggested Reading 160
33 - Perineal Hernia 162
INTRODUCTION 162
THERAPY 162
Patient Selection 162
Preoperative Preparation 162
Procedures 162
Alternative Methods 163
Postoperative Care 163
Complications 163
PREVENTION 164
SUMMARY 164
Suggested Reading 164
3 - COLON 165
34 - Preoperative Preparation of the Patient for Colon and Rectal Surgery 167
INTRODUCTION 167
RISK ASSESSMENT 167
CARDIOVASCULAR ASSESSMENT AND PREOPERATIVE MANAGEMENT 167
PREOPERATIVE PULMONARY ASSESSMENT AND MANAGEMENT 169
MANAGEMENT OF PATIENTS RECEIVING ANTITHROMBOTIC THERAPY 170
MANAGEMENT OF PREOPERATIVE ANEMIA 171
MANAGEMENT OF PREOPERATIVE MALNUTRITION 172
Suggested Reading 173
35 - Medical Treatment of Ulcerative Colitis and Other Colitides 174
ULCERATIVE COLITIS 174
Diagnosis 174
Treatment 174
Diet 174
5-Aminosalycilic Acid 174
Mild to Moderate Ulcerative Colitis 174
Proctitis and Left-Sided Ulcerative Colitis 176
Left-Sided Disease 176
Extensive Disease 177
Lack of Response to 5-Aminosalycilic Acid 177
Oral Budesonide 177
Corticosteroids 177
Severe Ulcerative Colitis 177
Cyclosporine 177
Azathioprine and 6-Mercaptopurine 178
Biologic Agents 178
Infliximab 178
Loss of Response. It is known that antibodies can develop in patients receiving anti-TNF-α agents with a loss of response to tre... 178
Infusion Reactions. Mild infusion reactions occur in 5% to 13% of patients, but severe infusion reactions requiring infliximab d... 179
Delayed Reactions. Delayed reactions occur 3 to 12 days after the administration of infliximab. These reactions result from the ... 179
Adalimumab 179
Golimumab 179
How to Choose an Anti-TNF-α Agent 179
Complications 179
What to Do Before Starting Anti-TNF-α Therapy 179
What to Do Once Treatment with an Anti-TNF-α Agent Is Started 179
Antiadhesion Molecules 180
Alternative Therapies 180
Nicotine 180
Clinical Scenarios 180
Quiescent Disease 180
Fulminant or Toxic Colitis 180
General Recommendations for Patients with Severe Ulcerative Colitis 181
Test for C. difficile Toxin A and B 181
Flexible Sigmoidoscopy with Biopsies 181
Deep Vein Thrombosis Prophylaxis 181
Evaluate for Tuberculosis and Hepatitis B 181
Avoid Narcotics and Antidiarrheal Medications 181
Do Not Use Antibiotics 181
Diet as Tolerated 181
Perform Close Observation and Consult Colorectal Surgery upon Admission 181
Vaccinations 181
Pregnancy 181
Cancer Risk 181
Colorectal Cancer Prevention 183
OTHER COLITIDES 183
Microscopic Colitis 183
Diversion Colitis 183
Radiation Colopathy 184
Drug-Induced Colitis 184
Suggested Reading 184
36 - Chronic Ulcerative Colitis: Surgical Options 186
INTRODUCTION 186
EVOLUTION OF SURGERY FOR ULCERATIVE COLITIS 186
INDICATIONS FOR SURGERY IN PERSONS WITH ULCERATIVE COLITIS 186
OPERATIONS FOR ULCERATIVE COLITIS 186
Ileostomy 186
Straight Ileoanal Anastomosis 186
Subtotal Colectomy 186
Abdominal Colectomy with Ileorectal Anastomosis 187
Ileostomy and Blowhole Colostomy 187
Total Proctocolectomy and Ileostomy 187
Proctectomy Surgical Technique 187
Continent Ileostomy 187
Restorative Proctocolectomy 188
Pouch Configuration and Anastomosis 188
Staging the Procedure 188
Technique of Creation of an Ileoanal J Pouch 188
Problems with Reach of the Pouch 188
OUTCOMES OF ILEAL POUCH–ANAL ANASTOMOSIS 189
Complications after Ileal Pouch–Anal Anastomosis 189
Overall Quality of Life 189
Function of the Pouch 189
Pouchitis 189
Pouch Failure 189
Pouch Fistula 189
Risk of Carcinoma 189
Fertility, Sexual Problems, and Obstetric Outcome 189
Extraintestinal Manifestations 189
Quantification of Risk for Pouch Failure after Ileal Pouch Anal Anastomosis Surgery 190
Salvage of the Failed Pelvic Pouch 190
Suggested Reading 190
37 - Management of Acute Toxic Colitis and Megacolon 191
INTRODUCTION 191
EPIDEMIOLOGY AND ETIOLOGY 191
PATHOPHYSIOLOGY 191
PRESENTATION 191
DIAGNOSIS 191
EVALUATION 192
MEDICAL MANAGEMENT 193
SURGICAL MANAGEMENT 195
Indications for Surgery 195
Surgical Options 195
CONCLUSION 196
Suggested Reading 196
38 - Pelvic Pouch: Complications and Their Management 197
INTRODUCTION 197
POUCH DYSFUNCTION 197
INTRAOPERATIVE COMPLICATIONS 197
POSTOPERATIVE COMPLICATIONS 197
Pelvis Sepsis and Anastomotic Leak 198
Postoperative Bleeding from the Pouch 198
Pouch-Perineal and Pouch-Vaginal Fistulae 198
Pouch Sinus 198
Leak from the Tip of the “J” 199
Pouch Prolapse 199
Pouchitis and Cuffitis 199
Crohn Disease of the Pouch 199
Outlet Dysfunction 199
Cancer of the Pouch 199
Pouch Failure 199
ABDOMINOPERINEAL APPROACH FOR POUCH SALVAGE 199
Operative Technique 200
Suggested Reading 200
39 - Pouchitis and Functional Complications of the Pelvic Pouch 201
INTRODUCTION 201
POUCHITIS 201
ETIOLOGY AND PATHOGENESIS 201
Genetic Factors 201
The Microbiome 201
Mucosal Immunity 201
DIAGNOSIS 201
Categories of Pouchitis 202
TREATMENT 202
IRRITABLE POUCH SYNDROME 202
OTHER FUNCTIONAL DISORDERS 203
CONCLUSIONS 203
Suggested Reading 203
40 - Continent Ileostomy 204
INTRODUCTION 204
EVOLUTION OF THE CONTINENT ILEOSTOMY 204
TECHNIQUES TO BETTER FIX THE VALVE 204
POUCH DESIGN MODIFICATIONS 204
CURRENT INDICATIONS AND CONTRAINDICATIONS 205
CURRENT SURGICAL TECHNIQUE AND STATUS 205
Key Surgical Points 205
Typical Pouch Function 206
COMPLICATIONS OF A CONTINENT ILEOSTOMY 207
Perioperative Complications 207
Early Complications 207
Late Complications 207
Valve Slippage 207
Parastomal Hernia 207
Crohn Disease 207
Pouchitis 207
Valve Stenosis 207
Pouch Excision 207
WHAT TO DO WHEN A PATIENT PRESENTS ACUTELY WITH THE INABILITY TO INTUBATE HIS OR HER POUCH 208
CONCLUSIONS 208
Suggested Reading 208
41 - Unhealed Perineal Wound 209
INTRODUCTION 209
SPECIAL SITUATIONS LEADING TO AN UNHEALED PERINEAL WOUND 209
CAUSES 209
Technical Factors 209
Patient-Specific Factors 209
Crohn Disease 209
Radiation 209
PREVENTION 210
Preoperative 210
Intraoperative 210
Reconstruction of the Perineum with a Flap 210
DIAGNOSIS/WORKUP 211
NONOPERATIVE TREATMENT 211
OPERATIVE MANAGEMENT 211
SUMMARY 212
Suggested Reading 212
42 - Medical Management of Crohn Disease 213
INTRODUCTION 213
MEDICAL THERAPIES 213
5-Aminosalicylates 213
Antibiotics 213
Corticosteroids 213
Immunomodulators 213
Biologic Agents 214
Combination Therapy 214
PERIANAL AND FISTULIZING CROHN DISEASE 215
APPROACH TO MANAGEMENT OF CROHN DISEASE 215
SURGERY 216
POSTOPERATIVE RECURRENCE 216
SMOKING 216
NUTRITION 216
Suggested Reading 216
43 - Management of Crohn Colitis 217
MEDICAL MANAGEMENT 217
OPERATIVE INDICATIONS 217
PREOPERATIVE CONSIDERATIONS 217
OPERATIVE APPROACH 217
OPERATIVE OPTIONS 218
Disease of the Colon Alone 218
Disease of the Rectum Alone 218
Disease of the Colon and Rectum 218
SPECIAL SITUATIONS 219
Medications 219
Abscess 219
Severe Colitis 219
Growth Retardation 220
Fistula 220
Neoplasia 220
OUTCOME 220
SUMMARY 221
Suggested Reading 221
44 - Management of Perianal Crohn Disease 222
INTRODUCTION 222
PATHOPHYSIOLOGY 222
OTHER CONSIDERATIONS 222
PRESENTATIONS 222
Anal Sepsis 222
Anal Tags 222
Fissures 222
Stenosis 223
Perianal Skin Irritation 223
Internal Hemorrhoidal Prolapse 223
TREATMENT OF SEPSIS: ABSCESS AND FISTULA 223
RECTO/ANOVAGINAL FISTULA 224
OTHER MANIFESTATION OF PERIANAL CROHN DISEASE 224
SUMMARY 224
Suggested Reading 225
45 - Cecal Ulcer 226
INTRODUCTION 226
CAUSES 226
DIAGNOSIS 226
MANAGEMENT 227
CONCLUSION 227
Suggested Reading 227
46 - Pseudomembranous Clostridium Difficile Colitis 228
INTRODUCTION 228
PRESENTATION OF CLOSTRIDIUM DIFFICILE INFECTION 228
DIAGNOSIS 228
MEDICAL MANAGEMENT 229
SURGICAL MANAGEMENT 229
CONCLUSION 230
Suggested Reading 230
47 - Cytomegalovirus Ileocolitis and Kaposi Sarcoma in HIV/AIDS 231
INTRODUCTION 231
CYTOMEGALOVIRUS COLITIS 231
SURGERY 232
KAPOSI SARCOMA 232
Suggested Reading 233
48 - Diagnosis and Management of Acute Colonic Diverticulitis 234
INTRODUCTION 234
PRESENTATION 234
DIAGNOSTIC EVALUATION 234
MEDICAL MANAGEMENT 235
SURGICAL MANAGEMENT 235
Surgery 237
Suggested Reading 237
49 - Surgical Treatment of Diverticulitis and its Complications 239
INTRODUCTION 239
UNDERSTANDING DIVERTICULAR DISEASE AND ITS MANAGEMENT 239
ACUTE UNCOMPLICATED DIVERTICULITIS 239
Who Requires Elective Surgery after Uncomplicated Diverticulitis? 239
COMPLICATED DIVERTICULITIS 240
Acute Diverticulitis Complicated by Abscess Formation: Converting an Emergency Situation into a Semi-Elective Procedure 240
Acute Diverticulitis Complicated by Purulent or Feculent Peritonitis: Surgical Options in the Emergency Setting 241
Hartmann Procedure and Reversal 241
COMPLICATED DIVERTICULITIS WITH FISTULA FORMATION 242
Colovesical Fistulas: Diagnosis and Management 242
Colovaginal Fistulas: Diagnosis and Management 242
Colocutaneous Fistulas: Diagnosis and Management 242
ACUTE COLONIC OBSTRUCTION: PATIENT SELECTION FOR EMERGENT VERSUS SEMI-ELECTIVE OPERATIONS 242
RECURRENT DIVERTICULITIS IN PATIENTS WHO HAVE PREVIOUSLY UNDERGONE RESECTION FOR DIVERTICULAR DISEASE 243
Suggested Reading 243
50 - Lower Gastrointestinal Hemorrhage 244
INTRODUCTION 244
ETIOLOGY 244
INITIAL EVALUATION AND RESUSCITATION 244
DIAGNOSTIC TESTING 245
Scintigraphy 245
Multidetector Computed Tomography 246
Angiography 246
Colonoscopy 246
SURGERY 247
THE PROBLEM PATIENT: INTERMITTENT RECURRENT GASTROINTESTINAL BLEEDING 247
Suggested Reading 248
51 - Large Bowel Obstruction 249
INTRODUCTION 249
CLINICAL AND DIAGNOSTIC EVALUATION 249
SURGICAL MANAGEMENT 250
MALIGNANT AND BENIGN OBSTRUCTION 250
Right-Sided Obstruction 251
Left-Sided Obstruction 251
Self-Expanding Metallic Stents 252
COLONIC VOLVULUS 253
SIGMOID VOLVULUS 253
CECAL VOLVULUS 254
Suggested Reading 254
52 - Colonic Volvulus 255
INTRODUCTION 255
CECAL VOLVULUS 255
Background and Demographics 255
Pathophysiology 255
Signs and Symptoms 255
Diagnostic Imaging 255
Treatment 255
SIGMOID VOLVULUS 256
Background and Demographics 256
Pathophysiology 256
Signs and Symptoms 256
Diagnostic Imaging 256
Treatment 256
TRANSVERSE COLON VOLVULUS 258
Background and Demographics 258
Pathophysiology 259
Diagnostic Imaging 259
Signs and Symptoms 259
Treatment 259
Suggested Readings 259
53 - Colonic Pseudo-obstruction (Ogilvie Syndrome) 260
INTRODUCTION 260
EPIDEMIOLOGY 260
ETIOLOGY 260
SIGNS AND SYMPTOMS 260
DIAGNOSIS 261
TREATMENT OPTIONS 261
Initial Management 261
Pharmacologic Management 261
Endoscopic Therapy 262
Surgery 262
SUMMARY 262
Suggested Reading 262
54 - Management of the Malignant Polyp 264
INTRODUCTION 264
BIOLOGY 264
ASSESSMENT OF POLYPS 264
POLYPECTOMY 264
HISTOLOGY 264
MARGIN 265
NODES 265
SURGICAL CONSIDERATIONS 265
COMORBIDITIES 266
SUMMARY 266
Suggested Reading 266
55 - Colorectal Cancer Screening and Surveillance 267
SCREENING FOR COLORECTAL CANCER 267
Who Should Be Screened? Determining Risk 267
Screening Average-Risk Persons 267
CANCER PREVENTION TESTS 267
Colonoscopy 267
Flexible Sigmoidoscopy 268
Computed Tomographic Colonography 268
CANCER DETECTION TESTS 269
Fecal Occult Blood Tests 269
Stool DNA 269
SCREENING IN PERSONS AT AN ABOVE-AVERAGE RISK FOR COLORECTAL CANCER 269
Surveillance Colonoscopy in Patients with Adenomatous Lesions at Baseline 269
Surveillance Colonoscopy in Patients with Serrated Lesions at Baseline 270
Surveillance Colonoscopy after Piecemeal Polypectomy 270
Surveillance Colonoscopy after Endoscopic Resection of a Malignant Polyp 271
Surveillance Colonoscopy in Patients with Colorectal Cancer 271
Surveillance Colonoscopy in Patients with Inflammatory Bowel Disease 271
Surveillance Colonoscopy in Patients with a Family History of Colorectal Cancer or Adenomatous Polyps 271
WHEN SHOULD SCREENING AND SURVEILLANCE STOP IN THE AVERAGE-RISK POPULATION? 271
CONCLUSION 271
Suggested Readings 271
56 - Molecular Genetics of Colorectal Cancer 273
INTRODUCTION 273
GROWTH CONTROL 273
DNA REPAIR 273
CLINICAL SIGNIFICANCE 273
COMPLEXITY 274
Suggested Reading 274
57 - Polyposis Syndromes 275
INTRODUCTION 275
REGISTRIES 275
DEFINITIONS 275
FAMILIAL ADENOMATOUS POLYPOSIS 275
Genetic Testing 275
Genotype/Phenotype 275
Colorectal Cancer in Familial Adenomatous Polyposis 276
Surgical Options for the Large Bowel 276
Extracolonic Manifestations 276
Ampullary Cancer and Duodenal Adenomas 277
Thyroid Cancer 277
Adrenal Masses 277
Brain Tumors 277
Hepatoblastoma 277
Gardner-Type Manifestations 277
Congenital Hypertrophy of the Retinal Pigmented Epithelium 277
Surveillance 278
The IRA 278
The IPAA 278
Oligopolyposis/Attenuated Familial Adenomatous Polyposis 278
MYH-ASSOCIATED POLYPOSIS (MAP) 278
POLYMERASE PROOFREADING–ASSOCIATED POLYPOSIS 279
SERRATED POLYPOSIS 279
HAMARTOMATOUS POLYPOSES 279
Peutz-Jegher Polyposis 279
Juvenile Polyposis 279
PTEN Tumor Hamartoma Syndrome 280
HEREDITARY MIXED POLYPOSIS SYNDROME 280
Suggested Reading 280
58 - Desmoid Disease 281
INTRODUCTION 281
BIOLOGY 281
EPIDEMIOLOGY 281
GENETICS AND DESMOID RISK 281
DESMOID SEVERITY: A STAGING SYSTEM 281
MANAGEMENT 282
Setting Expectations 282
A Philosophy of Care 282
Extra-abdominal Desmoid Tumors 282
Abdominal Wall Tumors 282
Intra-abdominal Desmoid Disease 282
Workup 282
Medical Treatment 282
Role of Surgery 283
Complications of Desmoid Disease 283
Small Bowel Obstruction 283
Ureteric Obstruction 283
Abscess/Enterocutaneous Fistula 283
Superior Mesenteric Artery Aneurysm 284
Points about Operating on Persons with Desmoid Disease 284
SUMMARY AND GENERAL COMMENTS ABOUT THE EFFECT OF DESMOID DISEASE ON SURGICAL STRATEGY IN FAMILIAL ADENOMATOUS POLYPOSIS 284
Suggested Reading 284
59 - Hereditary Nonpolyposis\rColorectal Cancer and Lynch Syndrome 285
INTRODUCTION 285
HISTORICAL PERSPECTIVE AND CLARIFICATION OF TERMS 285
GENETIC AND MOLECULAR CAUSE OF LYNCH SYNDROME 285
HISTOLOGIC FEATURES OF LYNCH TUMORS 285
DIAGNOSING LYNCH SYNDROME 286
Clinical Criteria 286
Models 286
Tumor Testing 286
GENETIC COUNSELING AND TESTING 287
CLINICAL MANIFESTATIONS AND MANAGEMENT 288
COLORECTAL CANCER RISK MANAGEMENT 288
Surveillance Colonoscopy and Polypectomy 288
Chemoprevention 288
Surgery 289
Colectomy in the Absence of Cancer 289
Treatment of Colon Cancer 289
Rectal Cancer in Persons with Lynch Syndrome 289
RISK MANAGEMENT OF EXTRACOLONIC MANIFESTIONS 289
Endometrial and Ovarian Cancer 289
Upper Gastrointestinal Tract 290
Urinary Tract 290
Skin Neoplasms 290
Other Cancers 290
CLINICAL VARIATIONS OF HNPCC AND LYNCH SYNDROME 290
Familial Colorectal Cancer Type X 290
Likely Lynch Syndrome: Amsterdam Criteria with a Microsatellite Instability High Colorectal Cancer, but Germline Testing Is Not ... 290
Tumor Lynch 291
SUMMARY 291
Suggested Reading 291
60 - Cancer of the Appendix and Pseudomyxoma Peritonei Syndrome 292
INTRODUCTION 292
PATHOLOGY OF APPENDICEAL MALIGNANT TUMORS 292
Carcinoid Tumors 292
Adenocarcinoid Tumors of the Appendix (Goblet Cell Carcinoid) 292
Epithelial (Noncarcinoid) Tumors of the Appendix 292
Mucinous Adenoma and Adenocarcinoma 292
Nonmucinous Adenocarcinoma 293
DIAGNOSIS OF APPENDICEAL MALIGNANT TUMORS 293
Carcinoid 293
Adenocarcinoma and Mucinous Adenocarcinoma 294
Pseudomyxoma Peritonei Syndrome 294
TREATMENT OF APPENDICEAL TUMORS 295
Carcinoid Tumors 295
Appendiceal Adenocarcinoma 296
Management of Appendiceal Neoplasms with Peritoneal Dissemination 296
Perioperative Chemotherapy 297
Serial Debulking 297
CYTOREDUCTIVE SURGERY AND PERIOPERATIVE CHEMOTHERAPY 298
Survival by Completeness of Cytoreduction 298
Survival by Histologic Assessment 298
Survival by Prior Surgical Score 298
Treatment of Adenocarcinoid Appendiceal Malignancy 298
Morbidity and Mortality Rates 299
Peritonectomy 299
Perioperative Chemotherapy 300
Suggested Reading 300
61 - Surgical Management of Cancer of the Colon 301
INTRODUCTION 301
EPIDEMIOLOGY 301
Prognostic Factors 301
PREOPERATIVE EVALUATION 301
PREOPERATIVE PREPARATION 301
OPERATIVE PRINCIPLES AND TECHNIQUES 302
Exploration 302
Surgical Treatment of Right Colon Cancer 302
Surgical Treatment of Transverse Colon Cancer 304
Surgical Treatment of Splenic Flexure and Descending Colon Cancer 304
Surgical Treatment of Sigmoid Colon Cancer 305
LAPAROSCOPIC COLECTOMY 306
SPECIAL CONSIDERATIONS 306
Obstruction and Perforation 306
Prophylactic Oophorectomy 307
ASSESSMENT OF QUALITY OF COLECTOMY 307
POSTOPERATIVE SURVEILLANCE 307
SUMMARY 307
Suggested Readings 308
62 - Management of Metastatic Colorectal Cancer 309
INTRODUCTION 309
CHEMOTHERAPY 309
5-Fu 309
Capecitabine 309
Irinotecan 309
Oxaliplatin 311
MAINTENANCE CHEMOTHERAPY 311
BIOLOGIC AGENTS 311
FIRST-LINE TARGETED OPTIONS 312
THIRD- AND FOURTH-LINE OPTIONS 312
OLIGOMETASTATIC DISEASE 312
ROLE OF RESECTION OF PRIMARY LESION 313
IMMUNOTHERAPY 313
CONCLUSIONS 313
Suggested Reading 313
63 - Management of Colorectal Liver Metastasis 314
INTRODUCTION 314
DIAGNOSIS AND PREOPERATIVE WORKUP 314
Imaging 314
Serologic and Molecular Markers 314
Histology 314
Needle Biopsy 314
Multidisciplinary Planning 314
STAGING AND PROGNOSIS 314
PROGNOSTIC SCORES 315
TREATMENT 315
Chemotherapy 315
Neoadjuvant Chemotherapy for Resectable Liver Disease 315
Neoadjuvant Chemotherapy for Unresectable Liver Disease 315
Adjuvant Chemotherapy 315
Hepatic Arterial Infusion 316
Resectability 316
Resectable Liver Disease 316
Synchronous Liver Metastasis 316
Unresectable Liver Disease 317
Repeat Resections for Multiple Liver Metastases 317
Local Ablative Therapy 317
Radiofrequency Ablation 317
Microwave Ablation 318
Cryotherapy 318
Irreversible Electroporation 318
Colorectal Liver Metastases with Extrahepatic Spread 318
Lung 318
Peritoneal 318
Lymph Node Involvement 318
Inferior Vena Cava 318
Recurrence 318
SURVEILLANCE 318
CONCLUSION 318
Suggested Readings 318
64 - Colorectal Metastases to the Lung 320
INTRODUCTION 320
INDICATIONS FOR RESECTION OF COLORECTAL METASTASES 320
OUTCOMES OF PATIENTS UNDERGOING RESECTION AND PROGNOSTIC FACTORS 320
LUNG AND LIVER METASTASIS 321
SURGICAL APPROACH 321
DEVELOPMENT OF A PROSPECTIVE RANDOMIZED TRIAL: THE PULMONARY METASTASECTOMY IN COLORECTAL CANCER TRIAL 322
CONCLUSION 322
Suggested Reading 322
65 - Nonepithelial Colorectal Tumors 323
INTRODUCTION 323
BENIGN NONADENOMATOUS LESIONS OF THE COLON AND RECTUM 323
Benign Lymphoid Hyperplasia 323
Lipomas 323
Treatment 323
CAVERNOUS HEMANGIOMA 323
Characteristic Features 324
Treatment 325
Surgery (Laparotomy/Laparoscopic) 325
LEIOMYOMA AND LEIOMYOSARCOMA 326
Characteristic Features 326
Surgery 326
PRIMARY LYMPHOMA OF THE COLON AND RECTUM 326
SUMMARY 327
Suggested Reading 327
66 - Management of Colonic Ischemia 328
INTRODUCTION 328
ETIOLOGY AND PATHOGENESIS 328
CLASSIFICATION 328
CLINICAL PRESENTATION 329
DIAGNOSIS 330
MANAGEMENT 330
OUTCOME 331
SPECIAL TOPICS 331
Ischemic Colitis after Aortic Surgery 331
Colonic Ischemia after Cardiopulmonary Bypass 332
Ischemic Colitis Associated with Colon Carcinoma and Obstructing Colon Lesions 332
Total Colonic Ischemia 332
Ischemic Proctosigmoiditis 332
CONCLUSION 333
Suggested Readings 333
67 - Colon and Rectal Trauma 334
INTRODUCTION 334
ETIOLOGY 334
DIAGNOSIS 334
Physical Examination 334
Imaging 334
Diagnostic Peritoneal Lavage 335
Laparoscopy 335
TREATMENT 336
Colon Injuries 336
Damage Control 337
Rectal Injuries 338
Overview 338
Diversion 338
Direct Repair 338
Drainage 338
Distal Washout 338
Rectal Foreign Bodies 339
Suggested Reading 340
68 - Endometriosis of the Colon and Rectum 341
INTRODUCTION 341
PAIN 341
INFERTILITY 341
DIAGNOSIS 341
Physical Examination 341
Endoscopy 341
Imaging 342
SURGICAL MANAGEMENT 342
Results after Surgical Therapy 343
Combined Medical and Surgical Therapy 343
CONCLUSION 343
Suggested Reading 343
69 - Pneumatosis Cystoides Intestinalis 345
INTRODUCTION 345
ETIOLOGY 345
CLASSIFICATION 345
HISTOLOGY AND GROSS PATHOLOGY 345
SYMPTOMS 345
DIAGNOSIS 346
TREATMENT 347
Suggested Readings 348
70 - Constipation 349
INTRODUCTION 349
CAUSES 349
CLASSIFYING CONSTIPATION 349
ASSESSMENT 349
History 349
Physical Examination 350
INVESTIGATIONS 350
TREATMENT 351
Medical 351
Newer Promotility Agents 352
Biofeedback for Pelvic Floor Dyssynergia 352
Change in Position of Defecation 352
Surgery 352
Outlet Obstruction Constipation 355
Suggested Reading 355
4 - SMALL INTESTINE 357
71 - Small Bowel Obstruction 359
EXTENT OF THE PROBLEM 359
CLINICAL PRESENTATION 359
IMAGING 359
MRI and Ultrasound 360
MANAGEMENT OF SMALL BOWEL OBSTRUCTION 360
Nonadhesive Obstruction 361
Hernias 361
Crohn Disease 361
Malignancy 361
Intussusception 361
Gallstone Ileus 361
Bariatric Patient 361
Surgical Technique 361
Adhesive Obstruction 361
Hernias 362
Crohn Disease and Other Inflammatory Conditions 362
Malignancy 362
Intussusception 363
Gallstone Ileus 363
The Bariatric Patient 363
Laparoscopic versus Open Lysis of Adhesions 363
Early Postoperative Bowel Obstruction 363
Prevention of Adhesions 363
SUMMARY 364
Suggested Reading 365
72 - Medical Management of Short Bowel Syndrome 366
INTRODUCTION 366
ANATOMY OF SHORT BOWEL SYNDROME 366
DIETARY MANAGEMENT OF SHORT BOWEL SYNDROME 366
PHARMACOLOGIC TREATMENT OF SHORT BOWEL SYNDROME 366
PARENTERAL AND ENTERAL NUTRITION 366
HORMONAL TREATMENT FOR SHORT BOWEL SYNDROME 369
COMPLICATIONS ASSOCIATED WITH SHORT BOWEL SYNDROME 369
CONCLUSION 370
Suggested Reading 371
73 - Surgery for Gut Failure: Auto-Reconstruction and Allo-Transplantation 372
INTRODUCTION 372
GUT ADAPTATION 372
MEDICAL MANAGEMENT 372
SURGICAL REHABILITATION 373
Strategy 373
Autologous Reconstruction 373
Intestinal Lengthening 376
INTESTINAL AND MULTIVISCERAL TRANSPLANTATION 376
Types 376
Indications 377
Contraindications 378
Early Referral 378
Transplantation Surgery 378
Postoperative Management 379
Current Global Activities 380
Long-Term Survival 380
Allograft Function 381
Quality of Life 381
New Insights 382
SUMMARY 383
Suggested Reading 383
74 - Crohn Disease of the Duodenum, Stomach, and Esophagus 385
INTRODUCTION 385
CLINICAL PRESENTATION 385
INVESTIGATIONS IN UPPER GASTROINTESTINAL CROHN DISEASE 385
MEDICAL TREATMENT 386
ENDOSCOPIC TREATMENT 386
SURGERY 386
SUMMARY 387
Suggested Readings 387
75 - Management of Small Bowel Crohn Disease 388
INTRODUCTION 388
MEDICAL MANAGEMENT 388
INDICATIONS FOR SURGERY 388
PREOPERATIVE CONSIDERATIONS 388
OPERATIVE APPROACH 388
SURGICAL OPTIONS 389
Bypass 389
Resection 389
Strictureplasty 390
SPECIAL SITUATIONS 390
Medications 390
Abscess 390
Free Perforation 390
Hemorrhage 390
Growth Retardation 390
Fistula 390
Neoplasia 390
Obstruction 390
OUTCOME 392
SUMMARY 392
Selected Reading 392
76 - Small Bowel Neoplasms 393
INTRODUCTION 393
PRESENTATION 393
DIAGNOSIS 393
MANAGEMENT 394
Adenocarcinoma without Metastatic Disease 394
Carcinoid Tumors 394
Lymphomas 395
GIST Tumors 395
CONCLUSION 395
ACKNOWLEDGMENT 395
Suggested Readings 395
77 - Neuroendocrine Tumors of the Small and Large Intestine 396
DEFINITION 396
INCIDENCE, EPIDEMIOLOGY, AND RESEARCH 396
CLINICAL PRESENTATION 397
DIAGNOSIS 397
CLASSIFICATION 398
SURGICAL TREATMENT 398
Small Intestine 398
Appendix 398
Colon 398
Rectum 398
Locally Advanced and Metastatic Disease 399
Hedinger Syndrome 402
ADJUVANT THERAPY 402
FOLLOW-UP 403
PROGNOSIS 403
Suggested Reading 403
78 - Enterocutaneous Fistulas 404
INTRODUCTION 404
PATHOGENESIS 404
GENERAL ASPECTS OF CARE 404
COMPLICATIONS 404
PLAN OF CARE 404
Prevention 404
Stabilization 406
Wound Care 406
Nutritional Support 407
Nasogastric Tubes and Other Drainage Tubes 407
Protection of the Gastric, Duodenal, and Upper Gastrointestinal Tract Mucosa from Ulceration 407
Other Supplements 407
Investigation/Elucidation 407
Therapeutic Decisions 407
Will It Close? 407
The Decision to Operate 407
Definitive Therapy 408
Timing of Surgery 408
Surgery 408
Choice of Incision 408
The Operation Itself 408
Anastomosis 409
Abdominal Wound Closure 409
What Type of Operation Should One Undertake? 409
Gastrostomy and Feeding Jejunostomy 410
The Healing Phase 410
Fibrin Glue 410
Short Bowel Syndrome 410
PROGNOSIS 410
Suggested Reading 411
79 - Acute and Chronic Mesenteric Ischemia 412
INTRODUCTION 412
ACUTE MESENTERIC ISCHEMIA 412
Clinical Presentation 412
Evaluation 413
Treatment 413
SMA Embolus 414
SMA Thrombus 414
Mesenteric Venous Thrombosis 414
Nonocclusive Mesenteric Ischemia 414
Bowel Viability 414
Laparoscopy 415
CHRONIC MESENTERIC ISCHEMIA 415
Presentation 416
Evaluation 416
Operative Treatment 416
Angioplasty 416
CONCLUSION 417
Suggested Readings 417
80 - Radiation Enteritis and Proctocolitis 418
BACKGROUND 418
PATHOPHYSIOLOGY 418
PREDISPOSING RISK FACTORS 418
GRADING SYSTEMS 418
DIAGNOSTIC WORKUP 418
PREVENTION 419
MANAGEMENT OF RADIATION ENTERITIS 419
Management of Radiation Injury to the Small Bowel 419
Acute Radiation Enteritis 419
Chronic Radiation Enteritis 419
Management of Radiation Injury to the Colon 420
Acute Radiation Colitis 420
Chronic Radiation Colitis 420
Management of Radiation Injury to the Rectum 420
Topical Therapy 421
Hyperbaric Oxygen 421
Medical Therapy 421
Endoscopic Management 421
Surgery 421
CONCLUSION 422
Suggested Readings 422
5 - COMPLICATIONS (AND OTHER MISCELLANEOUS TOPICS) 425
81 - Colorectal Surgery in the High-Risk Patient 427
INTRODUCTION 427
IDENTIFICATION OF THE HIGH-RISK PATIENT 427
MINIMIZING RISK ASSOCIATED WITH EMERGENCY SURGERY 428
MINIMIZING RISK ASSOCIATED WITH CARDIAC DISEASE 429
MINIMIZING RISK ASSOCIATED WITH PULMONARY DISEASE 430
MINIMIZING RISK ASSOCIATED WITH IMMUNOSUPPRESSION 431
Steroids 431
Diabetes 431
Chemoradiotherapy 431
MINIMIZING RISK ASSOCIATED WITH MALNUTRITION 432
MINIMIZING RISK ASSOCIATED WITH HEPATIC DISEASE 432
MINIMIZING RISK ASSOCIATED WITH RENAL DISEASE 433
MINIMIZING RISK IN MORBIDLY OBESE PATIENTS 433
Suggested Reading 433
82 - Reoperative Pelvic Surgery 434
INTRODUCTION 434
ANATOMIC FACTORS 434
The Ureters 434
Presacral Veins 434
Pelvic Nerves 434
POSTOPERATIVE CHANGES IN THE PELVIS 434
Approach to Reoperative Pelvic Surgery 434
Preoperative Planning 434
Timing 434
Patient Preparation 435
Define the Anatomy 435
Anticipate and Prepare for a Difficult Case 435
Functional Considerations 435
Intraoperative Conduct 435
Patient Positioning 435
Optimizing Visibility and Exposure 435
Access to the Pelvis 436
Identification of Specific Pelvic Structures 436
Ureter 436
Bladder 436
Rectal Stump 436
Vagina 437
Autonomic Nerves 437
Control of Bleeding 437
Drainage 437
SPECIFIC CLINICAL SITUATIONS 437
Reversal of Hartmann Procedure for Diverticulitis 437
Recurrent Rectal Cancer 437
Redo Ileoanal Pelvic Pouch Procedure 438
SUMMARY 438
Suggested Reading 438
83 - Nutritional Support in Colorectal Surgery 439
INTRODUCTION 439
NUTRITIONAL ASSESSMENT 439
INDICATIONS FOR NUTRITIONAL SUPPORT 439
General Indications 439
Severe Malnutrition 439
Postoperative Nutrition 439
Specific CRS Indications 440
Inflammatory Bowel Disease 440
Colorectal Cancer 440
ESTIMATION OF NUTRIENT REQUIREMENTS 440
Calories 440
Protein 440
DIETARY COMPOSITION AND DELIVERY 441
Hospital-Based Diets 441
Clear Liquid Diet 441
Regular Diet 441
Low-Residue Diet 441
Oral Supplements 441
Liquid Formula Diets 441
Enteral Nutrition 441
Access for EN 442
Early Postoperative Feeding: “Fast Track” 443
Parenteral Nutrition 443
Access for PN 443
Concomitant EN and PN 443
Overfeeding 444
NEW DIRECTIONS 444
Immunonutrition 444
Preoperative Carbohydrate Loading 444
SUMMARY 444
Suggested Reading 444
84 - Prevention and Management of Sepsis 445
BACKGROUND 445
PREVENTION 445
Defining Risk 445
Preventive Measures 445
Bowel Preparation 445
Prophylactic Antibiotics 445
Intact Anastomosis 445
Tension-Free Anastomosis 445
Well-Vascularized Anastomosis 445
Consideration for Diversion 445
Appropriate Use of Drains 446
MANAGEMENT OF INTRA-ABDOMINAL SEPSIS 446
Goal-Directed Hemodynamic Support 446
Evaluation 446
Nonoperative Interventions 446
Operation versus Observation 447
Open Abdomen 447
Return to the Operating Room 447
Suggested Readings 447
85 - Management of Anastomotic Leak 448
INTRODUCTION 448
WHAT DEFINES A LEAK? 448
PRINCIPLES OF MANAGEMENT 448
EARLY DIAGNOSIS 448
IMAGING 448
CRP LEVELS 448
ENDOSCOPY 449
VARIABLES DIRECTING MANAGEMENT 449
Location: Intraperitoneal versus Extraperitoneal 449
Type of Anastomosis: Ileocolic versus Colorectal/Ileorectal 449
Symptoms: Sepsis versus Symptomatic versus Asymptomatic 449
Previously Diverted: Proximal Diverting Ostomy versus Nondiverted 450
LEAK MANAGEMENT TOOLS 450
ENDO-VACUUM ASSISTED CLOSURE 450
ENDOSCOPIC STENTS, CLIPS, AND GLUE 450
TRANSANAL REPAIR TECHNIQUES 451
TURNBULL-CUTAIT PULL THROUGH 451
SUMMARY 451
Suggested Reading 451
86 - Complications of Colonoscopy 452
INTRODUCTION 452
RISK MANAGEMENT 452
HEMORRHAGE 452
Steps Prior to Colonoscopy 452
Risk Factors for Bleeding 453
Prevention of Bleeding 453
Treatment of Bleeding 453
PERFORATION 454
Causes of Perforation 454
Diagnosis of Perforation 454
Management of Perforation 454
Suggested Readings 455
87 - Management of Hemorrhage during Pelvic Surgery 456
INTRODUCTION 456
PERTINENT ANATOMY 456
BLEEDING 458
TACTICS FOR CONTROL OF PELVIC BLEEDING 458
Major Vessel Bleeding 458
Iliac Vessels 458
Minor Vessel Bleeding 459
Presacral Bleeding 459
Pelvic Packing 459
Suture Ligation 459
Thumbtacks 459
Muscle Fragment Welding 459
Bipolar Electrocautery 459
Hemostasis Step-by-Step Technique 460
Hemostatic Agents 460
Mechanical Hemostatic Agents 460
Active Hemostatic Agents 460
Flowable Hemostatic Agents 461
Fibrin Sealants 461
CONCLUSION 461
Selected Reading 461
88 - Urologic Issues in Colorectal Surgery 462
INTRODUCTION 462
INFECTION 462
URETER 462
BLADDER 463
URETHRA 464
REPRODUCTIVE STRUCTURES 465
NERVES 465
BLOOD VESSELS 467
Suggested Readings 467
89 - Prevention and Treatment of Complications of Laparoscopic Colorectal Surgery 468
INTRODUCTION 468
GENERAL COMPLICATIONS 468
Contraindications 468
Peritoneal Access Complications 468
Pneumoperitoneum Complications 468
Thromboembolic Complications 469
Electrosurgical Complications 469
Positioning Complications 469
Bleeding Complications 469
Tumor Identification Difficulties 470
Contamination 470
Anastomosis Complications 470
Urologic Complications 471
CONCLUSIONS 471
Suggested Reading 471
90 - Prevention and Management of Ostomy Complications 472
INTRODUCTION 472
OSTOMY CREATION 472
Preoperative Discussion and Consent 472
Siting the Stoma 472
Creating and Maturing the Stoma 473
End Ileostomy 474
Loop Ileostomy 474
COMPLICATIONS 474
Early Complications 474
Appliance Issues/Skin Irritation 474
Ischemia 474
Stoma Stenosis 475
Retraction 475
Late Complications 475
Parastomal Hernia 475
Prolapse 475
Stricture 475
Peristomal Pyoderma 475
Parastomal Ulcer 475
Abscess and Fistula 476
SUMMARY 476
Suggested Reading 476
91 - Stoma and Wound Considerations: Nursing Management 477
PREOPERATIVE PREPARATION 477
Preoperative Counseling 477
Stoma Site Marking 477
POSTOPERATIVE MANAGEMENT 477
SPECIAL CONSIDERATIONS 478
Continent ileostomy 478
WOUND MANAGEMENT 478
POSTDISCHARGE FOLLOW-UP 478
COLOSTOMY IRRIGATION 478
ILEOSTOMY LAVAGE 484
CONCLUSION 484
Suggested Readings 485
92 - Measuring Outcomes 486
INTRODUCTION 486
TYPES OF OUTCOME MEASURES 486
Structural Measures 486
Process Measures 486
Outcome Measures 487
Person-Centered Outcomes 487
MEASURING QUALITY OF LIFE 487
Instruments for Assessing Quality of Life 488
Colorectal Cancer Care 488
Inflammatory Bowel Disease 488
Fecal Incontinence 488
Sexual Function 488
CONSIDERATIONS IN CHOOSING OUTCOME MEASURES 488
SUMMARY 489
Suggested Readings 489
93 - Medical Documentation and Coding for the Colorectal Surgeon 490
INTRODUCTION 490
PROCESS OF CPT CODE DEVELOPMENT 490
CPT CODING FOR EVALUATION AND MANAGEMENT SERVICES 490
Office Evaluation and Management Coding 490
HOSPITAL-BASED EVALUATION AND MANAGEMENT DOCUMENTATION AND CODING 491
CPT CODING FOR SURGICAL PROCEDURES 492
SUMMARY 492
Suggested Reading 492
94 - Enhanced Recovery Pathways After Colorectal Surgery 493
BACKGROUND 493
COMPONENTS OF EVIDENCE-BASED CARE 493
EVIDENCE FOR IMPROVED OUTCOME 493
Colonic Surgery 493
Rectal Surgery 493
Other Colorectal Procedures 493
IMPLEMENTATION STRATEGY AND TREATMENT ALGORITHM 494
Colonic Surgery Protocol 494
Rectal Surgery Protocol 494
THE WAY FORWARD 494
Suggested Readings 495
95 - Managing Complex Ventral/Parastomal Hernias in Colorectal Surgical Patients 496
INTRODUCTION 496
PERMANENT ENTEROSTOMY—PARASTOMAL HERNIA REPAIR 496
Open Repair 496
Laparoscopic Repair 497
TEMPORARY ENTEROSTOMY 498
PROSTHETIC CHOICE 498
HERNIA REPAIR IN INFLAMMATORY BOWEL DISEASE 499
CONCLUSION 500
Selected Reading 500
Index 501
A 501
B 502
C 503
D 506
E 507
F 507
G 508
H 508
I 509
J 510
K 510
L 510
M 511
N 511
O 512
P 512
Q 514
R 514
S 515
T 516
U 517
V 517
W 518
Z 518
IBC ES2