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Salters-Nuffield A level Biology Student Book 2

Salters-Nuffield A level Biology Student Book 2

Ann Scott | Nicola Wilberforce | Nick Owens | David Slingsby | Mark Smith | Author

(2016)

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Abstract

Salters-Nuffield A level Biology Student Book 2

Table of Contents

Section Title Page Action Price
Cover Cover
Contents iii
Contributors iv
About the SNAB course v
How to use this book vi
Topic 5: On the wild side 2
Chapter 5.1: What is an ecosystem? 4
Habitats 4
Communities and populations 5
What determines which species occur in a habitat? 5
Abiotic factors 5
Biotic factors 6
Adapted for survival 8
Ecosystems are dynamic 9
Primary succession 10
Secondary succession 12
Deflected succession 12
Chapter 5.2: Ecosystems rely on energy transfer 13
Producers and productivity 13
Photosynthesis 14
An overview 14
How photosynthesis works 15
Where does photosynthesis take place? 16
The light-dependent reactions 17
the light-independent reactions 20
The fate of glucose 21
Transfer of energy through the ecosystem 22
Energy transfer and feeding relationships 22
How efficient is the transfer of energy through the ecosystem? 23
Chapter 5.3: Is the climate changing? 27
Evidence for climate change 27
Temperature records over long periods 27
Studying peat bogs 27
Tree-ring analysis - dendrochronology 30
Putting the data together 31
Changing rainfall patterns 32
Chapter 5.4: Why is the climate changing? 33
Keeping the earth warm – the greenhouse effect 33
Which are the greenhouse gases? 34
Does increased carbon dioxide cause global warming? 36
A controversial issue 37
Chapter 5.5: Predicting future climates 39
Making mathematical models 39
A really reliable model 39
Extrapolation 39
Taking into account many factors at once 40
Do not expect models to be perfect 41
Climate model predicts a colder UK 42
Chapter 5.6: Coping with climate change 43
Changing distribution of species 43
Changing communities and alien invaders 43
Altered development 45
Faster photosynthesis – faster growth 45
A complex picture 47
Disrupted development and life cycles 48
Phenology: changing with the seasons 49
Making the most of the food supply 49
Chapter 5.7: Adapt or die 50
Changing over time 50
We now know 51
Evidence for evolution 51
Validating new evidence 51
Molecular evidence 52
Evolution observed 54
Speciation 55
What is a species? 55
How are new species formed? 55
Allopatric speciation 56
Sympatric speciation 57
It is not always clear cut! 58
Chapter 5.8: Getting the balance right 59
Out of balance 60
Combustion of fossil fuels 60
Deforestation 60
What else could upset the carbon dioxide balance? 61
The mystery of the disappearing carbon dioxide 62
Maintaining the balance 62
Using sustainable resources 62
Reforestation 63
Action needed to reduce climate change – not everyone agrees 63
Thinking Bigger 64
Topic 6: Infection, immunity and forensics 66
Chapter 6.1: Forensic biology 68
Identifying the body 68
DNA profiling 71
How is a DNA profile made? 73
Obtaining the DNA 73
Creating the fragments 73
Polymerase chain reaction 74
Separating the fragments 74
Visualising the fragments 76
Using the DNA profile 78
Is DNA profiling infallible? 79
Determining time of death 79
Body temperature 79
Rigor mortis 80
Decomposition 81
Forensic entomology 81
Estimating time since death 82
Other decomposers 85
Chapter 6.2: Cause of death 86
What killed George Watson and Nicki Overton? 86
How might Nicki have become infected? 90
Transmission of the TB bacterium 90
Transmission of HIV 91
Chapter 6.3: The body’s response to infection 92
Non-specific responses to infection 92
Lysozyme 92
Inflammation 93
Phagocytosis 93
Antimicrobial proteins – interferon 95
Specific immunity 96
B and T cells 96
The primary immune response 98
The secondary immune response 102
Avoiding attack by our own immune system 102
Chapter 6.4: The body’s response to TB 104
What is tuberculosis? 104
Symptoms of the disease 105
Primary infection with TB 105
Active tuberculosis 107
Glandular TB 108
How is TB diagnosed? 108
Skin and blood tests 108
Identification of bacteria 108
Chest X-rays 109
Chapter 6.5: The body’s response to HIV and AIDS 110
What are HIV and AIds? 110
HIV invades T helper cells 112
HIV hijacks the cell’s protein synthesis 112
New virus particles destroy T helper cells 115
The course of the disease – AIDS 115
The acute phase 115
The chronic phase 116
The disease phase 116
Chapter 6.6: Could the infections have been prevented? 117
Preventing entry of pathogens 117
The skin 117
Mucous membranes 117
Digestive system 117
Stomach acid 117
Gut flora 117
Becoming immune 118
Being vaccinated 119
Are vaccinations dangerous? 121
Chapter 6.7: Are there treatments for AIDS and TB? 122
Treating AIDS 122
Treating tuberculosis 122
What are antibiotics? 122
Searching for new antibiotics 123
Why do some microorganisms make antibiotics? 124
How antibiotics work 124
Classifying antibiotics 124
How antibiotics disrupt bacterial cell growth and division 124
Why do we still have diseases like TB? 125
We are not winning the race 125
Antibiotics provide another selection pressure 125
Antibiotic-resistant tb 126
Multiple-resistant bacteria 126
Antibiotic resistance and hospital acquired infections 127
Thinking Bigger 128
Topic 7: Run for your life 130
Chapter 7.1: Getting moving 132
Joints and movement 132
Joint structure 133
Muscles 135
How do muscles work? 135
Inside a muscle fibre 136
How the sarcomere shortens 138
Chapter 7.2: Energy for action 141
Releasing energy 141
Carbohydrate oxidation 142
Glycolysis first 142
The fate of pyruvate if oxygen is available 144
Fate of the hydrogens – the electron transport chain 145
The fate of pyruvate without oxygen 150
Chapter 7.3: Peak performance 154
Cardiac output 154
Stroke volume 154
Heart rate 155
Control of heart rate 157
Breathing 163
Lung volumes 163
The control of breathing 164
All muscle fibres are not the same 167
Slow twitch fibres 167
Fast twitch fibres 168
Chapter 7.4: Breaking out in a sweat 169
Temperature control 172
Temperature control receptors and effectors 172
Temperature regulation during exercise 174
Chapter 7.5: Overdoing it 177
Excessive exercise and immune suppression 178
Effects of exercise on immunity 178
How are joints damaged by exercise? 180
How can medical technology help? 180
Taking enough exercise 183
Chapter 7.6: Improving on nature 184
Performance-enhancing substances 184
Hormones 185
How hormones affect cells 186
Performance-enhancing substances not banned 190
Should performance-enhancing substance use be banned? 191
Thinking Bigger 192
Topic 8: Grey matter 194
Chapter 8.1: The nervous system and nerve impulses 196
What are nerve cells like? 196
Reflex arcs 198
The pupil reflex 199
How nerve cells transmit impulses 201
Inside a resting axon 202
What happens when a nerve is stimulated? 204
What causes an action potential? 204
How is the impulse passed along an axon? 206
Are impulses different sizes? 206
Speed of conduction 206
How does a nervous impulse pass between cells? 208
Synapse structure 208
How does the synapse transmit an impulse? 208
What is the role of synapses in nerve pathways? 210
Control and coordination 210
Types of synapse 211
Chapter 8.2: Reception of stimuli 215
How does light trigger nerve impulses? 215
Receptors 215
Plants can also detect and respond to environmental cues 219
Phytochromes – plant photoreceptors 219
Plants detect other environmental cues 223
Chapter 8.3: The brain 224
The cerebral hemispheres 224
The cerebellum and brain stem 225
Discovering the function of each brain region 226
Studies of individuals with damaged brain regions 226
Brain imaging 229
Positron Emission Tomography 231
From the eye to the brain 232
Chapter 8.4: Visual development 233
Axon growth 233
Evidence for a critical period in visual development 234
Medical observations 234
Research using animal models 235
What is happening during the critical period for developmentof vision? 236
Chapter 8.5: Making sense of what we see 238
Depth perception 238
Close objects 238
Distant objects 238
Is depth perception innate or learned? 239
Cross-cultural studies 239
Studies with newborn babies 241
Chapter 8.6: Learning and memory 243
Where memories are stored 243
How memories are stored 243
Sea slugs and habituation – changing synapse strength 243
More connection - longer memory 245
The ethics of using animals in medical research 246
Animal welfare rather than animal rights 247
Animal suffering and experience of pleasure 247
A utilitarian approach to the use of animals 247
Chapter 8.7: Problems with the synapses 248
Parkinson’s disease 248
Dopamine and parkinson’s disease 248
Treatment for parkinson’s disease 248
Excess dopamine 249
Depression 250
Serotonin and depression 250
Drug treatment for depression 251
How drugs affect synaptic transmission 251
The effect of ecstasy 252
Better treatments 252
How the outcomes of genome sequencing projects help 253
Using genetically modified organisms to produce drugs 257
Genetic modification 257
Concerns about genetic modification 262
Thinking Bigger 266
Answers 268
Index 287