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Mosby's Diagnostic and Laboratory Test Reference - E-Book

Mosby's Diagnostic and Laboratory Test Reference - E-Book

Kathleen Deska Pagana | Timothy J. Pagana | Theresa N Pagana

(2016)

Additional Information

Book Details

Abstract

Gain quick access to today’s most important diagnostic tests and procedures with Mosby’s Diagnostic & Laboratory Test Reference, 13th Edition! In this bestselling handbook, concise test entries are arranged alphabetically and reflect the latest in diagnostic testing and research. Each test includes vital information such as alternate or abbreviated test names, test explanation, normal and abnormal findings, possible critical values, and guidelines to patient care before, during, and after the test. To simplify lookup, related tests are cross-referenced. From the expert author team of Kathleen, Timothy, and Theresa Pagana, this reference offers convenient A-to-Z thumb tabs, a compact size, and a durable cover for everyday use on the job.

  • UNIQUE! Each test entry begins on a new page, making tests easy to find.
  • Alphabetically organized tests offer quick reference with A-to-Z thumb tabs, so you’ll never have to search for a test by having to first determine its correct category or body system.
  • User’s Guide to Test Preparation and Performance provides an overview and guidelines for each type of laboratory test and diagnostic procedure, so you can minimize worry about having to repeat a test due to an error.
  • Icon for patient teaching-related care indicates information that should be shared with patients and their families.
  • Normal findings for adult, elderly, and pediatric patients are included where applicable.
  • Abnormal findings are highlighted with directional arrows to show increased or decreased test results.
  • Possible critical values are highlighted to alert you to situations requiring immediate intervention.
  • Convenient appendix lists tests by body system and test type, making it easy to quickly locate related studies.
  • Drug interference with test results is indicated by a mortar and pestle icon. 
  • Cross-referencing of related tests makes them easy to find.
  • Abbreviations for tests are listed in the front and the back of the book, and symbols and units of measurement are listed in an appendix.
  • A durable cover with rounded edges helps prevent the book from being damaged and makes it easier to handle.
  • NEW test entries include the latest diagnostic tests and laboratory procedures.
  • NEW! Updated coverage reflects the latest research on the diagnostic values of results, accuracy of testing, and patient care and education for each test.

Table of Contents

Section Title Page Action Price
Front Cover Cover
IFC ES1
MOSBY’S DIAGNOSTIC AND LABORATORY TEST REFERENCE i
Copyright ii
Dedication iii
reviewers\r iv
preface\r v
contents ix
list of figures\r x
user’s guide to test preparation and procedures\r xi
Overview xi
Urine tests xiv
Overview xiv
Guidelines xiv
Stool tests xv
Overview xv
Guidelines xvi
X-ray studies xvi
Overview xvi
Radiation dose xvii
Risk of radiation xvii
Radiation associated with diagnostic testing xviii
Guidelines xix
Nuclear scanning xxi
Overview xxi
Guidelines xxi
Ultrasound studies xxii
Overview xxii
Guidelines xxii
Endoscopy procedures xxiii
Overview xxiii
Guidelines xxiii
A 1
abdominal ultrasound (Abdominal sonogram) 1
Interfering factors 2
Procedure and patient care 2
Before 2
During 3
After 3
Abnormal findings 3
Kidney 3
Gallbladder 3
Liver 3
Pancreas 3
Bile ducts 4
Abdominal aorta 4
Abdominal cavity 4
acetylcholine receptor antibody panel (AChR Ab,\rAnti–AChR antibody) 5
Interfering factors 6
Procedure and patient care 6
Abnormal findings 6
acid phosphatase (Prostatic acid phosphatase [PAP],\rTartrate-resistant acid phosphatase [TRAP]) 7
Interfering factors 7
Procedure and patient care 7
Abnormal findings 8
activated clotting time (ACT, Activated coagulation time) 9
Depends on use for the test and clinical situation 9
Interfering factors 10
Procedure and patient care 10
Abnormal findings 10
adrenocorticotropic hormone (ACTH, Corticotropin) 11
Type of testBlood 11
Interfering factors 12
Procedure and patient care 12
Abnormal findings 12
adrenocorticotropic hormone stimulation test with cosyntropin (ACTH stimulation test, Cortisol stimulation test) 13
Interfering factors 14
Procedure and patient care 14
Rapid test 14
24-hour test 14
3-day test 14
Abnormal findings 14
In Cushing syndrome 15
Increase higher than normal response 15
adrenocorticotropic hormone stimulation test\rwith metyrapone (ACTH stimulation test with metyrapone, Metyrapone test) 16
Contraindications 16
Potential complications 16
Interfering factors 17
Procedure and patient care 17
During 17
Blood 17
Urine 17
After 17
Abnormal findings 17
Increased cortisol precursors 17
No change in cortisol precursors 17
adrenal steroid precursors (Androstenediones [AD], Dehydroepiandrosterone\r[DHEA], Dehydroepiandrosterone sulfate [DHEA S], 11-Deoxycortisol, 17-Hydroxyprogesterone, 17-Hydroxypregnenolone, Pregnenolone) 18
Interfering factors 19
Procedure and patient care 19
Abnormal findings 19
age-related macular degeneration risk analysis\r(ARMD risk analysis, Y402H, and A69S) 20
Procedure and patient care 20
Abnormal findings 20
alanine aminotransferase (ALT, formerly Serum glutamic-pyruvic transaminase [SGPT]) 21
Type of testBlood 21
Interfering factors 21
Procedure and patient care 21
Abnormal findings 22
aldolase 23
Type of testBlood 23
Interfering factors 23
Procedure and patient care 23
Abnormal findings 24
aldosterone 25
Type of testBlood; urine (24-hour) 25
Blood 25
Urine (24-hour) 25
Test explanation and related physiology 25
Interfering factors 26
Procedure and patient care 26
During 27
After 27
Abnormal findings 27
alkaline phosphatase (ALP) 29
Type of testBlood 29
Interfering factors 29
Procedure and patient care 30
Abnormal findings 30
allergy blood testing (IgE antibody test, Radioallergosorbent test [RAST]) 31
Test explanation and related physiology 31
Contraindications 32
Interfering factors 32
Procedure and patient care 32
Abnormal findings 32
allergy skin testing 33
Type of testSkin 33
Contraindications 34
Potential complications 34
Interfering factors 34
Procedure and patient care 34
During 35
Prick-puncture method 35
Intradermal method 35
Patch method 35
After 35
Abnormal findings 36
alpha1-antitrypsin (A1AT, AAT, Alpha1-antitrypsin phenotyping) 37
Type of testBlood 37
Interfering factors 37
Procedure and patient care 38
Abnormal findings 38
alpha-fetoprotein (AFP, a1-Fetoprotein) 39
Type of testBlood 39
Interfering factors 39
Procedure and patient care 39
Abnormal findings 40
aluminum 41
Type of testBlood 41
Interfering factors 41
Procedure and patient care 41
Abnormal findings 42
amino acid profiles (Amino acid screen) 43
Type of testBlood; urine 43
Interfering factors 43
Procedure and patient care 44
During 44
After 44
Abnormal findings 44
ammonia level 45
Type of testBlood 45
Interfering factors 45
Procedure and patient care 46
Abnormal findings 46
amniocentesis (Amniotic fluid analysis) 47
Type of testFluid analysis 47
Contraindications 50
Potential complications 50
Interfering factors 50
Procedure and patient care 50
During 51
After 52
Abnormal findings 53
amylase 54
Type of testBlood; urine 54
Blood 54
Urine (24-hour) 54
Possible critical values 54
Test explanation and related physiology 54
Interfering factors 55
Procedure and patient care 55
Abnormal findings 55
amyloid beta protein precursor, soluble\ramyloid beta protein precursor, soluble (sBPP) 56
Type of testCerebrospinal fluid (CSF) analysis 56
Procedure and patient care 56
During 56
After 56
Abnormal findings 56
angiotensin 57
Type of testBlood 57
Interfering factors 57
Procedure and patient care 57
Abnormal findings 57
angiotensin-converting enzyme (ACE, Serum angiotensin-converting enzyme [SACE]) 58
Type of testBlood 58
Interfering factors 58
Procedure and patient care 58
Abnormal findings 58
anion gap (AG, R factor) 60
Type of testBlood 60
Interfering factors 60
Procedure and patient care 61
Abnormal findings 61
anticardiolipin antibodies (aCL antibodies, ACA,\rAntiphospholipid antibodies, Lupus anticoagulant) 62
Type of testBlood 62
Interfering factors 62
Procedure and patient care 62
Abnormal findings 63
anticentromere antibody test (Centromere antibody) 64
Type of testBlood 64
Procedure and patient care 64
Abnormal findings 64
Positive results 64
(Antinucleosome antibody [anti-NCS], Antihistone antibody test [anti-HST, AHA]) 65
Type of testBlood 65
Antinucleosome antibodies 65
Antihistone antibody 65
Test explanation and related physiology 65
Procedure and patient care 66
Abnormal findings 66
antichromatin antibody test (Antinucleosome antibody [anti-NCS], Antihistone antibody test [anti-HST, AHA]) 67
Type of testBlood 67
Procedure and patient care 67
Abnormal findings 67
antidiuretic hormone (ADH, Vasopressin) 68
Type of testBlood 68
Interfering factors 69
Procedure and patient care 70
Abnormal findings 70
anti-DNA antibody test (Anti–deoxyribonucleic acid\rantibodies, Antibody to double-stranded DNA, Anti–double-stranded DNA, Anti–ds-DNA, DNA antibody, Native double-stranded DNA) 71
Type of testBlood 71
Interfering factors 71
Procedure and patient care 71
Abnormal findings 72
antiextractable nuclear antigens (Anti-ENAs, Antibodies to extractable nuclear antigens, Antihistidyl transfer synthase\r[anti–Jo-1], Antiribonucleoprotein [anti-RNP], Anti-Smith [anti-SM]) 73
Type of testBlood 73
Procedure and patient care 73
Abnormal findings 73
antiglomerular basement membrane antibodies\r(Anti-GBM antibody, AGBM, Glomerular basement antibody,\rGoodpasture antibody) 75
Type of testBlood; microscopic examination of tissue 75
Procedure and patient care 75
Abnormal findings 75
Positive 75
antiglycan antibodies (Crohn disease prognostic panel,\rMultiple sclerosis antibody panel) 76
Type of testBlood 76
Procedure and patient care 76
Abnormal findings 76
antiliver/kidney microsomal type 1 antibodies\r(Anti-LKM-1 antibodies) 77
Procedure and patient care 77
Abnormal findings 77
antimitochondrial antibody (AMA) 78
Type of testBlood 78
Procedure and patient care 78
Abnormal findings 78
antimyocardial antibody (AMA) 79
Type of testBlood 79
Procedure and patient care 79
Abnormal findings 79
antineutrophil cytoplasmic antibody (ANCA) 80
Type of testBlood 80
Procedure and patient care 81
Abnormal findings 81
antinuclear antibody (ANA) 82
Type of testBlood 82
Interfering factors 84
Procedure and patient care 85
Abnormal findings 85
antiparietal cell antibody (APCA) 86
Type of testBlood 86
Procedure and patient care 86
Abnormal findings 86
antiscleroderma antibody (Scl-70 antibody, Scleroderma antibody, RNA polymerase III antibody) 87
Type of testBlood 87
Interfering factors 87
Procedure and patient care 87
Abnormal findings 87
Positive results 87
antismooth muscle antibody (ASMA) 88
Type of testBlood 88
Procedure and patient care 88
Abnormal findings 88
antispermatozoal antibody (Sperm agglutination and\rinhibition, Sperm antibodies, Antisperm antibodies, Infertility screen) 89
Type of testFluid analysis; blood 89
Procedure and patient care 90
Sperm specimen 90
Abnormal findings 90
anti–SS-A (RO), anti–SS-B (LA), and anti–SS-C antibodies (Anti-Ro, Anti-La, Sjögren antibodies) 91
Type of testBlood 91
Procedure and patient care 92
Abnormal findings 92
Positive 92
antithrombin activity and antigen assay (Antithrombin III [AT-III] activity/assay, Functional antithrombin III assay, Heparin cofactor, Immunologic antithrombin III, Serine protease inhibitor) 93
Type of testBlood 93
Interfering factors 94
Procedure and patient care 94
Test results and clinical significance 94
antithyroglobulin antibody (Thyroid autoantibody, Thyroid antithyroglobulin antibody, Thyroglobulin antibody) 95
Type of testBlood 95
Interfering factors 95
Procedure and patient care 95
Abnormal findings 95
antithyroid peroxidase antibody (Anti-TPO, TPO-Ab,\rAntithyroid microsomal antibody, Thyroid autoantibody) 96
Procedure and patient care 96
Abnormal findings 96
antifactor Xa (Anti-Xa) 97
Type of testBlood 97
Adults and children > 8 weeks 97
Children <8 weeks 97
Test explanation and related physiology 97
Interfering factors 98
Procedure and patient care 98
Abnormal findings 98
apolipoproteins 99
Type of testBlood 99
Apo A-I 99
Apo B 99
Apo A-I/Apo B ratio 99
Lipoprotein (a) 99
Test explanation and related physiology 99
Interfering factors 100
Apo A-I 100
Apo B 101
Lipoprotein (a) 101
Procedure and patient care 101
Abnormal findings 101
apt test (Downey test, Qualitative fetal hemoglobin stool test, Stool for swallowed blood) 103
Type of testStool 103
Procedure and patient care 103
During 103
After 103
Abnormal findings 103
arterial blood gases (ABGs, blood gases) 104
Type of testBlood 104
pH 104
Pco2 104
HCO3 104
Po2 104
O2 saturation 104
O2 content 104
Base excess 104
Alveolar to arterial O2 difference 104
Possible critical values 104
Test explanation and related physiology 105
pH 105
Pco2 105
Bicarbonate (HCO3) or CO2 content 105
Po2 107
O2 saturation 107
O2 content 108
Base excess/deficit 108
Alveolar (A) to arterial (a) O2 difference (A-a gradient) 108
Contraindications 108
Potential complications 108
Interfering factors 109
Procedure and patient care 109
During 109
After 109
Abnormal findings 110
arteriography (Angiography) 112
Type of testX-ray with contrast dye 112
Contraindications 112
Potential complications 112
Procedure and patient care 113
During 113
After 114
Abnormal findings 114
Arteriography of the peripheral vascular system 114
Kidney arteriography 114
arthrocentesis with synovial fluid analysis 115
Type of testFluid analysis 115
Contraindications 117
Potential complications 117
Procedure and patient care 117
During 117
After 117
Abnormal findings 118
arthroscopy 119
Type of testEndoscopy 119
Contraindications 120
Potential complications 120
Procedure and patient care 120
During 120
After 121
Abnormal findings 121
aspartate aminotransferase (AST; Formerly called serum glutamic-oxaloacetic transaminase [SGOT]) 122
Type of testBlood 122
Normal findings 122
Test explanation and related physiology 122
Interfering factors 123
Procedure and patient care 123
1.1 Abnormal findings 123
B 125
barium enema (BE, Lower GI series) 125
Contraindications 125
Potential complications 125
Interfering factors 125
Procedure and patient care 126
Before 126
Day before examination 126
Day of examination 126
During 126
After 127
Abnormal findings 128
barium swallow 129
Type of test X-ray with contrast dye 129
Contraindications 129
Potential complications 129
Interfering factors 129
Procedure and patient care 129
During 130
After 130
Abnormal findings 130
Bence Jones protein (Free kappa and lambda light chains) 131
Type of test Urine 131
Interfering factors 132
Procedure and patient care 132
Abnormal findings 132
11 beta-prostaglandin F(2) alpha 133
Type of test Urine 133
Procedure and patient care 133
Abnormal findings 133
bilirubin 134
Type of test Blood 134
Possible critical values 134
Interfering factors 136
Procedure and patient care 136
Abnormal findings 136
bioterrorism infectious agents testing 138
Type of test Various (e.g. , blood, urine, stool, tissue culture, sputum, lymph node biopsy, skin) 138
Botulism infection 138
Anthrax 138
Hemorrhagic fever (yellow fever) 138
Plague 139
Brucellosis 139
Smallpox 139
Tularemia 139
Procedure and patient care 139
Before 139
During 140
After 140
Abnormal findings 140
bladder cancer markers (Bladder tumor antigen [BTA], Nuclear matrix protein 22 [NMP22]) 142
Type of test Urine 142
Interfering factors 143
Procedure and patient care 143
Abnormal findings 143
blood culture and sensitivity 144
Type of test Blood 144
Interfering factors 144
Procedure and patient care 144
During 145
After 145
Abnormal findings 145
blood smear (Peripheral blood smear, Red blood cell [RBC]\rmorphology, RBC smear) 146
Type of test Blood 146
Platelet examination 146
Procedure and patient care 148
During 148
After 148
Abnormal findings 148
blood typing (Blood group microarray testing) 149
Type of test Blood 149
ABO system 149
Rh factor 150
Other blood typing systems 151
Blood crossmatching 151
Procedure and patient care 151
Abnormal findings 151
bone densitometry (Bone mineral content [BMC], Bone mineral density [BMD], DEXA scan) 152
Type of test X-ray 152
Interfering factors 153
Procedure and patient care 153
During 154
After 154
Abnormal findings 154
bone marrow biopsy (Bone marrow examination, Bone marrow\raspiration) 155
Type of test Microscopic examination of tissue 155
Contraindications 157
Potential complications 157
Procedure and patient care 157
During 158
After 159
Abnormal findings 159
bone scan 160
Type of test Nuclear scan 160
Contraindications 161
Procedure and patient care 161
During 161
After 162
Abnormal findings 162
bone turnover markers (BTMs, N-telopeptide [NTx], Bone collagen\requivalents [BCEs], Osteocalcin [bone G1 a protein, BGP, osteocalc],\rPyridinium [PYD] crosslinks, Bone-specific alkaline phosphatase [BSAP], Amino-terminal propeptide of type I procollagen [P1NP], C-telopeptide [CTx]) 163
Type of test Blood; urine 163
N-telopeptide 163
C-telopeptide 163
Osteocalcin, serum (ng/mL) 163
Pyridium, urine (nm/mm) 163
Bone-specific alkaline phosphatase, serum (μg/L) 164
Interfering factors 165
Procedure and patient care 166
Blood 166
Urine 166
Anchor 538 166
Abnormal findings 166
bone x-ray 167
Type of test X-ray 167
Interfering factors 167
Procedure and patient care 167
During 168
After 168
Abnormal findings 168
brain scan (Cisternogram, Cerebral blood flow, DaT scan) 169
Type of test Nuclear scan 169
Contraindications 169
Interfering factors 169
Procedure and patient care 170
During 170
After 170
Abnormal findings 170
breast cancer genomics (Oncotype DX, Genotyping, MammaPrint) 171
Type of test Microscopic examination 171
Procedure and patient care 172
During 172
After 172
Abnormal findings 172
breast cancer tumor analysis (DNA ploidy status, S-phase fraction, Cathepsin D, HER-2 [c erbB2, neu] protein, p53 protein, Ki67 protein) 173
Type of test Microscopic examination 173
DNA ploidy 173
S-phase fraction 173
HER-2 protein 173
Cathepsin D 173
p53 protein 173
Ki67 protein 173
Test explanation and related physiology 173
DNA ploidy status and S-phase fraction 174
Cathepsin D 174
HER-2 (c erbB2, neu) protein 174
p53 protein 174
Ki67 protein 174
Interfering factors 174
Procedure and patient care 174
During 175
After 175
Abnormal findings 175
breast ductal lavage 176
Type of test Fluid analysis 176
Contraindications 176
Potential complications 176
Procedure and patient care 176
During 177
After 177
Abnormal findings 177
breast ultrasonography (Ultrasound mammography, Breast sonogram) 178
Type of test Ultrasound 178
Procedure and patient care 178
During 179
After 179
Abnormal findings 179
bronchoscopy 180
Type of test Endoscopy 180
Normal findings 180
Test explanation and related physiology 180
Contraindications 181
Potential complications 181
Procedure and patient care 181
During 181
After 183
Abnormal findings 183
C 184
calcitonin (Human calcitonin [HCT], Thyrocalcitonin) 184
Interfering factors 184
Procedure and patient care 185
Abnormal findings 185
calcium (Total/ionized calcium, Ca, Serum calcium) 186
Type of test Blood; urine 186
Possible critical values 186
Interfering factors 187
Procedure and patient care 188
Abnormal findings 188
caloric study (Oculovestibular reflex study) 189
Type of test Electrodiagnostic 189
Contraindications 189
Interfering factors 189
Procedure and patient care 189
During 189
After 190
Abnormal findings 190
cancer tumor markers (Tumor markers [TM], Tumor-associated\rmarkers) 191
Type of test blood 191
Interfering factors 191
Procedure and patient care 193
Abnormal findings 193
carbon dioxide content (CO2 content, CO2 combining power) 194
Type of test Blood 194
Possible critical values 194
Interfering factors 194
Procedure and patient care 195
Abnormal findings 195
carboxyhemoglobin (COHb, Carbon monoxide) 196
Type of test Blood 196
Possible critical values 196
Procedure and patient care 196
Abnormal findings 197
cardiac catheterization (Coronary angiography, Ventriculography) 198
Type of test X-ray with contrast dye 198
Contraindications 200
Potential complications 200
Procedure and patient care 201
During 202
After 203
Abnormal findings 203
cardiac nuclear scan (Myocardial perfusion scan, Myocardial perfusion imaging, Myocardial scan, Cardiac scan, Heart scan, Thallium scan, MUGA scan, Isonitrile scan, Sestamibi cardiac scan, Cardiac flow studies, and Nuclear stress test) 204
Type of test Nuclear scan 204
Contraindications 205
Interfering factors 205
Procedure and patient care 205
During 205
After 206
Abnormal findings 206
cardiac stress testing (Exercise stress testing; Nuclear stress testing; Echo stress testing) 207
Type of test Electrodiagnostic; nuclear 207
Contraindications 208
Potential complications 208
Interfering factors 209
Procedure and patient care 209
During 209
After 209
Abnormal findings 210
carotid artery duplex scanning (Carotid ultrasound) 211
Type of test Ultrasound 211
Procedure and patient care 211
During 212
After 212
Abnormal findings 212
cell culture drug resistance testing (CCDRT, Chemosensitivity\rassay, Drug response assay) 213
Type of test Miscellaneous 213
Procedure and patient care 213
During 213
After 213
Abnormal findings 213
cell-free maternal DNA testing (Noninvasive prenatal testing\r[NIPT, cell-free DNA in maternal blood]) 214
Type of test Blood 214
Procedure and patient care 215
Abnormal findings 215
cell surface immunophenotyping (Flow cytometry cell surface immunophenotyping, Lymphocyte immunophenotyping, AIDS T-lymphocyte cell markers, CD4 marker, CD4/CD8 ratio, CD4 percentage) 216
Type of test Blood 216
Contraindications 217
Interfering factors 217
Procedure and patient care 217
Abnormal findings 218
cervical biopsy (LEEP procedure, Cone biopsy) 219
Type of test Microscopic examination 219
Possible critical values 219
Contraindications 219
Potential complications 219
Procedure and patient care 220
During 220
After 220
Abnormal findings 221
chest x-ray (CXR) 222
Type of test X-ray 222
Contraindications 223
Interfering factors 223
Procedure and patient care 223
During 223
After 223
Abnormal findings 224
chlamydia 225
Type of test Blood; microscopic examination 225
Interfering factors 226
Procedure and patient care 226
During 226
After 227
Abnormal findings 227
chloride, blood (CL) 228
Type of test Blood 228
Possible critical values 228
Interfering factors 228
Procedure and patient care 228
Abnormal findings 229
cholesterol 230
Type of test Blood 230
Interfering factors 231
Procedure and patient care 231
Abnormal findings 232
cholinesterase (CHS, Pseudocholinesterase [PChE], Cholinesterase\rRBC, Red blood cell cholinesterase, Acetylcholinesterase) 233
Type of test Blood 233
Interfering factors 234
Procedure and patient care 234
Abnormal findings 235
chorionic villus sampling (CVS, Chorionic villus biopsy [CVB]) 236
Type of test Cell analysis 237
Potential complications 237
Procedure and patient care 237
During 237
After 239
Abnormal findings 239
chromosome karyotype (Blood chromosome analysis, Chromosome\rstudies, Cytogenetics, Karyotype) 239
Type of test Blood 239
Procedure and patient care 239
During 239
After 240
Abnormal findings 240
Clostridium difficile (C. diff, Clostridial toxin assay) 241
Type of test Stool 241
Procedure and patient care 242
During 242
After 242
Abnormal findings 242
coagulating factors concentration (Coagulating factors, Blood-clotting factors) 243
Type of test Blood 243
Interfering factors 245
Procedure and patient care 245
Abnormal findings 245
cold agglutinins 248
Type of test Blood 248
Interfering factors 248
Procedure and patient care 248
Abnormal findings 249
colon cancer tumor analysis (Microsatellite instability [MSI] testing, DNA mismatch repair [MMR] genetic testing, BRAF mutation analysis, Oncotype DX colon cancer assay) 250
Type of test Microscopic examination 250
Procedure and patient care 251
During 251
After 251
Abnormal findingsUnfavorable test results indicating a high risk of cancer reoccurrence 251
colonoscopy 252
Type of test Endoscopy 252
Contraindications 253
Potential complications 253
Interfering factors 253
Procedure and patient care 253
During 253
After 254
Abnormal findings 254
colposcopy 255
Type of test Endoscopy 255
Contraindications 257
Interfering factors 257
Procedure and patient care 257
During 257
After 257
Abnormal findings 258
complement assay (Total, C3 and C4 complement) 259
Type of testBlood 259
Interfering factors 260
Procedure and patient care 260
Abnormal findings 261
complete blood count and differential count (CBC and diff) 262
computed tomography of the abdomen and\rpelvis (CT scan of the abdomen and pelvis, Helical/spiral\rCT scan of the abdomen and pelvis) 263
Type of test X-ray with contrast dye 263
Contraindications 265
Potential complications 266
Interfering factors 266
Procedure and patient care 266
During 267
After 267
Abnormal findings 268
computed tomography of the brain (CT scan of the brain, Helical/spiral CT scan of the brain) 269
Type of test X-ray with contrast dye 269
Contraindications 270
Potential complications 270
Procedure and patient care 270
During 271
After 271
Abnormal findings 271
computed tomography of the chest (Chest CT scan,\rHelical/spiral CT scan of the chest) 272
Type of test X-ray with contrast dye 272
Contraindications 272
Potential complications 273
Procedure and patient care 273
During 273
After 274
Abnormal findings 274
computed tomography of the heart (Coronary CT angiography, Coronary calcium score) 275
Type of test X-ray with contrast dye 275
Contraindications 276
Potential complications 276
Procedure and patient care 276
During 277
After 277
Abnormal findings 277
Coombs test, direct (Direct antiglobulin test [DAT]) 278
Type of test Blood 279
Interfering factors 279
Procedure and patient care 279
Abnormal findings 279
Coombs test, indirect (Blood antibody screening, Indirect antiglobulin test [IAT]) 280
Type of test Blood 280
Interfering factors 280
Procedure and patient care 280
Abnormal findings 280
cortisol, blood, urine, saliva (Hydrocortisone, Serum cortisol,\rSalivary cortisol) 282
Type of test Blood; urine; saliva 282
Serum 282
Urine (24-hour) 282
Saliva 282
Test explanation and related physiology 282
Interfering factors 283
Procedure and patient care 283
During 283
After 284
Abnormal findings 284
C-peptide (Connecting peptide insulin, Insulin C-peptide, Proinsulin\rC-peptide) 285
Type of test Blood 285
Interfering factors 286
Procedure and patient care 286
Abnormal findings 286
C-reactive protein test (CRP, High-sensitivity C-reactive protein [hs-CRP]) 287
Type of test Blood 287
Interfering factors 288
Procedure and patient care 288
Abnormal findings 288
creatine kinase (CK, Creatine phosphokinase [CPK]) 289
Type of test Blood 289
Total CPK 289
Isoenzymes 289
Test explanation and related physiology 289
Interfering factors 291
Procedure and patient care 291
Abnormal findings 291
creatinine, blood (Serum creatinine) 293
Type of test Blood 293
Possible critical values 293
Interfering factors 294
Procedure and patient care 294
Abnormal findings 294
creatinine clearance (CC, Estimated glomerular filtration rate [eGFR]) 295
Type of test Urine (24-hour); blood 295
Interfering factors 296
Procedure and patient care 297
Abnormal findings 297
cryoglobulin 298
Type of testBlood 298
Procedure and patient care 298
Abnormal findings 298
cystography (Cystourethrography, Voiding cystography, Voiding cystourethrography [VCUG]) 299
Type of test X-ray with contrast dye 299
Contraindications 299
Potential complications 299
Procedure and patient care 299
During 300
After 300
Abnormal findings 300
cystometry (Cystometrogram [CMG]) 301
Type of test Manometric 301
Contraindications 302
Procedure and patient care 302
During 302
After 303
Abnormal findings 303
cystoscopy (Endourology) 304
Type of test Endoscopy 304
Potential complications 304
Procedure and patient care 305
During 306
After 307
Abnormal findings 308
cytokines (interleukins) 309
Type of test Blood 309
Interfering factors 310
Procedure and patient care 310
Abnormal findings 310
cytolethal distending toxin B (CdtB) and antivinculin antibodies 311
Type of test Blood 311
Procedure and patient care 311
Abnormal findings 311
cytomegalovirus (CMV) 312
Type of test Blood 312
Procedure and patient care 313
Abnormal findings 313
D 314
D-dimer (Fragment D-dimer, Fibrin degradation product [FDP], Fibrin split products) 314
Interfering factors 315
Procedure and patient care 315
Abnormal findings 315
delta-aminolevulinic acid (Aminolevulinic acid [ALA], d-ALA) 316
Type of test Urine (24-hour) 316
Possible critical values 316
Interfering factors 316
Procedure and patient care 316
Abnormal findings 316
dental x-ray (Dental radiography) 317
Type of test X-ray 317
Interfering factors 318
Procedure and patient care 318
During 318
After 318
Abnormal findings 318
dexamethasone suppression test (DST, Prolonged/rapid DST, Cortisol suppression test, ACTH suppression test) 319
Type of test Blood; urine (24-hour) 319
Prolonged method 319
Rapid (overnight) method 319
Test explanation and related physiology 319
Interfering factors 320
Procedure and patient care 320
During 320
Prolonged test 320
Rapid test 321
After 321
Abnormal findings 321
diabetes mellitus autoantibody panel (Insulin autoantibody\r[IAA], Islet cell antibody [ICA], Glutamic acid decarboxylase antibody [GAD Ab]) 322
Type of test Blood 322
Procedure and patient care 322
Abnormal findings 322
2,3-diphosphoglycerate (2,3-DPG in erythrocytes) 323
Type of test Blood 323
Interfering factors 323
Procedure and patient care 323
Abnormal findings 324
disseminated intravascular coagulation screening\r(DIC screening) 325
Type of test Blood 325
Abnormal findings 325
drug monitoring (Therapeutic drug monitoring [TDM]) 327
Type of test Blood 327
Pharmacogenetics (genetic testing for drug monitoring) 329
Procedure and patient care 329
During 330
After 331
Abnormal findings 331
drug sensitivity genotype testing (AccuType) 332
Type of test Blood 332
Procedure and patient care 332
Abnormal findings 332
ductoscopy (Mammary ductoscopy) 333
Type of test Endoscopy 333
Normal findings 333
Test explanation and related physiology 333
Interfering factors 333
Procedure and patient care 333
During 334
After 335
Abnormal findings 335
E 336
echocardiography (Cardiac echo, Heart sonogram, Transthoracic echocardiography [TTE]) 336
Contraindications 337
Interfering factors 337
Procedure and patient care 337
During 337
After 337
Abnormal findings 338
electrocardiography (Electrocardiogram [ECG, EKG]) 339
Type of test Electrodiagnostic 339
Interfering factors 342
Procedure and patient care 342
During 342
After 343
Abnormal findings 343
electroencephalography (Electroencephalogram [EEG]) 344
Type of test Electrodiagnostic 344
Interfering factors 345
Procedure and patient care 345
During 345
After 346
Abnormal findings 346
electromyography (EMG) 347
Type of test Electrodiagnostic 347
Contraindications 347
Potential complications 347
Interfering factors 347
Procedure and patient care 347
During 348
After 348
Abnormal findings 349
electromyography of the pelvic floor sphincter\r(Pelvic floor sphincter electromyography, Pelvic floor sphincter EMG, Rectal EMG procedure) 350
Type of test Electrodiagnostic 350
Contraindications 350
Procedure and patient care 350
During 351
After 351
Abnormal findings 351
electroneurography (ENG, Nerve conduction studies) 352
Type of test Electrodiagnostic 352
Interfering factors 352
Procedure and patient care 352
During 353
After 353
Abnormal findings 353
electronystagmography (Electrooculography) 354
Type of test Electrodiagnostic 354
Contraindications 354
Interfering factors 354
Procedure and patient care 355
During 355
After 355
Abnormal findings 355
electrophysiologic study (EPS, Cardiac mapping) 356
Type of test Electrodiagnostic; manometric 356
Tilt-table testing 356
Contraindications 356
Potential complications 357
Interfering factors 357
Procedure and patient care 357
During 357
Electrophysiologic study 357
Tilt-table test 358
After 358
Abnormal findings 358
endometrial biopsy 359
Type of test Microscopic examination of tissue 359
Contraindications 359
Potential complications 359
Procedure and patient care 359
During 360
After 360
Abnormal findings 360
endoscopic retrograde cholangiopancreatography (ERCP) 361
Type of test Endoscopy 361
Contraindications 362
Potential complications 362
Interfering factors 362
Procedure and patient care 362
During 362
After 364
Abnormal findings 364
epstein-barr virus testing (EBV antibody titer) 365
Type of test Blood 365
Procedure and patient care 367
Abnormal findings 367
erythrocyte fragility (Osmotic fragility [OF], Red blood cell fragility) 368
Type of test Blood 368
Interfering factors 368
Procedure and patient care 369
Abnormal findings 369
erythrocyte sedimentation rate (ESR, Sed rate test) 370
Type of test Blood 370
Westergren method 371
Test explanation and related physiology 371
Interfering factors 371
Procedure and patient care 371
Abnormal findings 371
erythropoietin (EPO) 372
Type of test Blood 372
Interfering factors 372
Procedure and patient care 372
Abnormal findings 373
esophageal function studies (Esophageal manometry, Esophageal motility studies) 374
Type of test Manometric 374
Manometry studies 374
Acid reflux with pH probe 374
Acid clearing 375
Bernstein test (acid perfusion) 375
Contraindications 375
Potential complications 375
Interfering factors 375
Procedure and patient care 375
During 376
After 377
Abnormal findings 377
esophagogastroduodenoscopy (EGD, Upper gastrointestinal\r[UGI] endoscopy, Gastroscopy) 378
Type of test Endoscopy 378
Contraindications 378
Potential complications 379
Interfering factors 379
Procedure and patient care 379
During 379
After 380
Abnormal findings 381
estrogen fractions (Estriol excretion, Estradiol, Estrone) 382
Type of test Urine (24-hour); blood 382
Possible critical values 382
Interfering factors 383
Procedure and patient care 383
Abnormal findings 384
estrogen receptor assay (ER assay, ERA, Estradiol receptor) 385
Type of test Microscopic examination 385
Interfering factors 385
Procedure and patient care 385
During 385
After 386
Abnormal findings 386
ethanol (Ethyl alcohol, Blood alcohol, Blood EtOH) 387
Type of test Blood; urine; gastric; breath 387
Possible critical values 387
Interfering factors 388
Procedure and patient care 388
Abnormal findings 388
evoked potential studies (EP studies, Evoked brain\rpotentials, Evoked responses) 389
Type of test Electrodiagnostic 389
Normal findings 389
Test explanation and related physiology 389
Procedure and patient care 390
During 391
After 391
Abnormal findings 391
Prolonged latency for VER 391
Prolonged latency for ABEP 391
Abnormal latency for SER 392
F 393
factor V Leiden (FVL, Mutation analysis) 393
Procedure and patient care 394
Abnormal findings 394
febrile antibodies (Febrile agglutinins) 395
Type of test Blood 395
Procedure and patient care 395
Abnormal findings 395
fecal fat (Fat absorption, Quantitative stool fat determination) 396
Type of test Stool 396
Interfering factors 396
Procedure and patient care 396
Before 396
During 397
After 397
Abnormal findings 397
ferritin 398
Type of test Blood 398
Interfering factors 398
Procedure and patient care 399
Abnormal findings 399
fetal biophysical profile (Biophysical profile [BPP]) 400
Type of test Ultrasound; fetal activity study 400
Score of less than 4 points may necessitate immediate delivery 400
Interfering factors 402
Procedure and patient care 402
During 402
After 402
Abnormal findings 402
fetal contraction stress test (Contraction stress test [CST], Oxytocin challenge test [OCT]) 403
Type of test Electrodiagnostic 403
Contraindications 404
Potential complications 404
Interfering factors 404
Procedure and patient care 404
During 404
After 405
Abnormal findings 405
fetal fibronectin (fFN) 406
Type of test Fluid analysis 406
Procedure and patient care 406
During 406
After 406
Abnormal findings 406
fetal hemoglobin (Kleihauer–Betke) 407
Type of test Blood 407
Interfering factors 407
Procedure and patient care 408
Abnormal findings 408
fetal nonstress test (Nonstress test [NST], Fetal activity determination) 409
Type of test Electrodiagnostic 409
Procedure and patient care 409
During 410
After 410
Abnormal findings 410
fetal scalp blood pH 411
Type of test Blood 411
Contraindications 411
Potential complications 411
Procedure and patient care 412
During 412
After 412
After delivery 412
Abnormal findings 412
fetoscopy 413
Type of test Endoscopy 413
Potential complications 413
Procedure and patient care 413
During 414
After 415
Abnormal findings 415
fibrinogen (Factor I, Quantitative fibrinogen) 416
Type of test Blood 416
Possible critical values 416
Interfering factors 416
Procedure and patient care 417
Abnormal findings 417
fluorescein angiography (FA, Ocular photography) 418
Type of test Other 418
Potential complications 418
Procedure and patient care 418
During 419
After 419
Abnormal findings 419
folic acid (Folate) 420
Type of test Blood 420
Interfering factors 420
Procedure and patient care 421
Abnormal findings 421
fungal testing (Antifungal antibodies; Beta-D-glucan, (1,3)-\rβ-D-glucan, Fungitell, Fungal culture, Fungal antigen assay, Fungal PCR testing) 422
Type of test Blood, microscopic examination 422
Normal findings 422
Test explanation and related physiology 422
Interfering factors 423
Procedure and patient care 423
Abnormal findings 423
G 424
galectin-3 (GAL-3) 424
Interfering factors 424
Procedure and patient care 424
Abnormal findings 424
gallbladder nuclear scanning (Hepatobiliary scintigraphy, Cholescintigraphy, DISIDA scanning, HIDA scanning) 425
Type of test Nuclear scan 425
Contraindications 425
Interfering factors 425
Procedure and patient care 426
During 426
After 426
Abnormal findings 426
gallium scan 427
Type of testNuclear scan 427
Contraindications 427
Interfering factors 427
Procedure and patient care 427
Before 427
During 428
After 428
Abnormal findings 428
gamma-glutamyl transpeptidase (GGTP, γ-GTP, Gamma-glutamyl transferase [GGT]) 429
Type of test Blood 429
Interfering factors 429
Procedure and patient care 429
Abnormal findings 430
gastric emptying scan 431
Type of test Nuclear scan 431
Contraindications 431
Interfering factors 431
Procedure and patient care 432
After 432
Abnormal findings 432
gastrin 433
Type of test Blood 433
Interfering factors 433
Procedure and patient care 434
Abnormal findings 434
gastroesophageal reflux scan (GE reflux scan, Aspiration scan) 435
Type of test Nuclear scan 435
Contraindications 435
Procedure and patient care 435
During 435
GE reflux scan 435
Aspiration scans 435
After 436
Abnormal findings 436
gastrointestinal bleeding scan (Abdominal scintigraphy, GI scintigraphy) 437
Type of test Nuclear scan 437
Contraindications 437
Interfering factors 437
Procedure and patient care 437
During 438
After 438
Abnormal findings 438
genetic testing (Breast cancer [BRCA] and ovarian cancer, Colon cancer, Cardiovascular disease, Tay-Sachs disease, Cystic fibrosis, Melanoma, Hemochromatosis, Thyroid cancer, Paternity [parentage analysis], Forensic genetic testing) 439
Type of test Blood; miscellaneous 439
Breast cancer and ovarian cancer genetic testing 439
Colon cancer genetic testing 440
Tay-Sachs disease genetic testing 441
Cystic fibrosis genetic testing 441
Melanoma genetic testing 442
Hemochromatosis genetic testing 442
Thyroid cancer genetic testing 443
Cardiac genetic testing 443
Paternity genetic testing (parentage analysis) 443
Forensic genetic testing 444
Contraindications 444
Procedure and patient care 444
During 445
After 445
Abnormal findings 445
gliadin, endomysial, and tissue transglutaminase antibodies 446
Type of test Blood 446
Interfering factors 446
Procedure and patient care 447
Abnormal findings 447
glucagon 448
Type of test Blood 448
Interfering factors 448
Procedure and patient care 449
Abnormal findings 449
glucose, blood (Blood sugar, Fasting blood sugar [FBS]) 450
Type of test Blood 451
Interfering factors 451
Procedure and patient care 451
Abnormal findings 452
glucose, postprandial (2-Hour postprandial glucose [2-Hour PPG], 1-Hour glucose screen) 453
Type of test Blood 453
Interfering factors 453
Procedure and patient care 453
Abnormal findings 454
glucose tolerance test (GTT, Oral glucose tolerance test [OGTT]) 455
Type of test Blood; urine 455
Plasma test 455
Urine test 455
Test explanation and related physiology 455
Contraindications 456
Potential complications 456
Interfering factors 456
Procedure and patient care 457
During 457
After 457
Abnormal findings 458
glycosylated hemoglobin (GHb, GHB, Glycohemoglobin, Glycolated hemoglobin, Hemoglobin [Hb A1c], Diabetic control index) 459
Type of test Blood 459
Interfering factors 461
Procedure and patient care 461
Abnormal findings 461
growth hormone (GH, Human growth hormone [HGH], Somatotropin\rhormone [SH]) 462
Type of test Blood 462
Interfering factors 463
Procedure and patient care 463
During 463
Growth hormone test 463
Growth hormone suppression test 464
After 464
Abnormal findings 464
growth hormone stimulation test (GH provocation test, Insulin tolerance test [ITT], Arginine test) 465
Type of test Blood 465
Normal findings 465
Test explanation and related physiology 465
Contraindications 465
Potential complications 465
Procedure and patient care 465
During 466
After 466
Abnormal findings 466
H 467
haptoglobin 467
Possible critical values 467
Interfering factors 467
Procedure and patient care 468
Abnormal findings 468
Heinz body preparation 469
Type of test Blood 469
Procedure and patient care 469
Abnormal findings 469
Helicobacter pylori testing (Anti–Helicobacter pylori antibody,\rCampylobacter-like organism [CLO] test, H. pylori stool antigen) 470
Type of test Blood; microscopic examination of antral or duodenal biopsy specimen; breath test; stool 470
Blood test 470
Stool test 470
Test explanation and related physiology 470
Contraindications 471
Interfering factors 471
Procedure and patient care 471
During 472
After 472
Abnormal findings 472
hematocrit (Hct, Packed red blood cell volume, Packed cell\rvolume [PCV]) 473
Type of test Blood 473
Possible critical values 473
Interfering factors 473
Procedure and patient care 474
Abnormal findings 475
hemoglobin (Hb, Hgb) 476
Type of testBlood 476
Possible critical values 476
Interfering factors 476
Procedure and patient care 477
Abnormal findings 477
hemoglobin electrophoresis (Hgb electrophoresis) 478
Type of testBlood 478
Interfering factors 480
Procedure and patient care 480
Abnormal findings 480
hepatitis virus studies 481
Type of testBlood 481
Procedure and patient care 485
Abnormal findings 485
herpes simplex (Herpesvirus types 1 and 2, Herpes simplex virus types 1 and 2 [HSV 1, HSV 2], Herpes genitalis) 486
Type of test Blood; microscopic 486
Procedure and patient care 486
During 487
Urethral culture 487
Cervical culture 487
Blood for serology 487
Molecular PCR tissue and other fluids 487
After 487
Abnormal findings 487
hexosaminidase (Hexosaminidase A, Hex A, Total\rhexosaminidase, Hexosaminidase A and B) 488
Type of test Blood 488
Interfering factors 489
Procedure and patient care 489
Abnormal findings 489
?Decreased hexosaminidase A 489
?Decreased hexosaminidase A and B 489
HIV drug resistance testing (HIV genotype) 490
Type of test Blood 490
Interfering factors 490
Procedure and patient care 490
Abnormal findings 490
HIV RNA quantification (HIV viral load) 491
Type of test Blood 491
Interfering factors 493
Procedure and patient care 493
Abnormal findings 493
HIV serologic and virologic testing (AIDS serology, Acquired immunodeficiency serology, AIDS screen, Human immunodeficiency\rvirus [HIV] antibody test, Western blot test, p24 direct antigen, HIV-RNA viral test) 494
Type of test Blood or fluid analysis (saliva) 494
Interfering factors 496
Procedure and patient care 496
Abnormal findings 497
Holter monitoring 498
Type of test Electrodiagnostic 498
Contraindications 499
Interfering factors 499
Procedure and patient care 499
During 500
After 500
Abnormal findings 500
homocysteine (Hcy) 501
Type of testBlood 501
Contraindications 501
Interfering factors 501
Procedure and patient care 502
Abnormal findings 502
human chorionic gonadotropin (hCG, Pregnancy tests, hCG beta subunit) 503
Type of testBlood; urine 503
Interfering factors 504
Procedure and patient care 504
During 505
After 505
Abnormal findings 505
human lymphocyte antigen B27 (HLA-B27 antigen, Human leukocyte A antigen, White blood cell antigens, Histocompatibility leukocyte A antigen) 506
Type of test Blood 506
Procedure and patient care 506
Abnormal findings 506
human papillomavirus (HPV test, HPV DNA testing) 508
Type of test Fluid analysis 508
Interfering factors 509
Procedure and patient care 509
During 509
After 510
Abnormal findings 510
human placental lactogen (hPL, Human chorionic somatomammotropin\r[HCS]) 511
Type of test Blood 511
Interfering factors 511
Procedure and patient care 512
Abnormal findings 512
human T-cell lymphotropic virus (HTLV) I/II antibody 513
Type of test Blood 513
Procedure and patient care 513
Abnormal findings 513
17-hydroxycorticosteroids (17-OCHS) 514
Type of test Urine (24-hour) 514
Interfering factors 514
Procedure and patient care 515
Abnormal findings 515
5-hydroxyindoleacetic acid (5-HIAA) 516
Type of test Urine (24-hour) 516
Interfering factors 516
Procedure and patient care 516
Abnormal findings 517
21-hydroxylase antibodies 518
Type of test Blood 518
Procedure and patient care 518
Abnormal findings 518
hysterosalpingography (Uterotubography, Uterosalpingography,\rHysterogram) 519
Type of test X-ray with contrast dye 519
Contraindications 519
Potential complications 519
Procedure and patient care 519
During 519
After 520
Abnormal findings 520
hysteroscopy 521
Type of test Endoscopy 521
Normal findings 521
Test explanation and related physiology 521
Contraindications 522
Potential complications 522
Procedure and patient care 522
During 522
After 523
Abnormal findings 523
I 524
immunoglobulin quantification 524
Type of test Blood 524
IgG (mg/dL) 524
IgA (mg/dL) 524
IgM (mg/dL) 524
IgD and IgE 524
Interfering factors 525
Procedure and patient care 525
Abnormal findings 525
insulin assay 527
Type of test Blood 527
Possible critical values 527
Interfering factors 528
Procedure and patient care 528
Abnormal findings 528
insulin-like growth factor (IGF-1, Somatomedin C, Insulin-like growth factor binding proteins [IGF BP]) 529
Type of test Blood 529
Interfering factors 530
Procedure and patient care 530
Abnormal findings 530
intravascular ultrasound (IVUS) 531
Type of test Ultrasound 531
Interfering factors 532
Procedure and patient care 532
During 532
After 532
Abnormal findings 532
intrinsic factor antibody (IF ab) 533
Type of test Blood 533
Interfering factors 533
Procedure and patient care 533
Abnormal findings 533
iron level and total iron-binding capacity (Fe and TIBC, Transferrin saturation, Transferrin) 534
Type of test Blood 534
Iron 534
TIBC 534
Transferrin 534
Transferrin saturation 534
Test explanation and related physiology 534
Serum iron 534
Total iron-binding capacity and transferrin 535
Total iron-binding capacity and transferrin saturation 535
Contraindications 536
Interfering factors 536
Procedure and patient care 536
Abnormal findings 537
ischemia-modified albumin (IMA) 538
Type of test Blood 538
Normal findings 538
Test explanation and related physiology 538
Procedure and patient care 538
Abnormal findings 538
L 539
lactic acid (Lactate) 539
Interfering factors 539
Procedure and patient care 539
Abnormal findings 540
lactic dehydrogenase (LDH, Lactate dehydrogenase) 541
Type of test Blood 541
Total 541
Isoenzymes 541
Test explanation and related physiology 541
Interfering factors 542
Procedure and patient care 542
Abnormal findings 542
lactoferrin 543
Type of test Stool 543
Interfering factors 543
Procedure and patient care 543
During 543
After 544
Abnormal findings 544
lactose tolerance test (Hydrogen breath test) 545
Type of test Blood 545
Interfering factors 546
Procedure and patient care 546
During 546
After 547
Abnormal findings 547
lead 548
Type of test Blood 548
Critical values 548
Test explanation and related physiology 548
Procedure and patient care 548
Abnormal findings 548
legionnaires disease antibody test 549
Type of test Blood 549
Procedure and patient care 549
Abnormal findings 549
leucine aminopeptidase (LAP) 550
Type of test Blood; urine (24-hour) 550
Blood 550
Urine 550
Test explanation and related physiology 550
Interfering factors 550
Procedure and patient care 550
Abnormal findings 550
lipase 551
Type of test Blood 551
Interfering factors 551
Procedure and patient care 551
Abnormal findings 552
lipoprotein-associated phospholipase A2\r(Lp-PLA2 PLAC test) 553
Type of test Blood 553
Procedure and patient care 553
Abnormal findings 553
lipoproteins (High-density lipoproteins [HDLs, HDL-C], Low-\rdensity lipoproteins [LDLs, LDL-C], Very-low-density lipoproteins [VLDLs], Lipoprotein electrophoresis, Lipoprotein phenotyping,\rLipid fractionation, Non-HDL cholesterol, Lipid profile) 554
Type of test Blood 554
Interfering factors 556
Procedure and patient care 556
Abnormal findings 556
liquid biopsy 558
Type of test Blood, urine, CSF 558
Procedure and patient care 558
Abnormal findings 558
liver biopsy 559
Type of test Microscopic examination of tissue 559
Contraindications 560
Potential complications 560
Procedure and patient care 560
During 560
After 561
Abnormal findings 561
liver/spleen scanning (Liver scanning) 562
Type of testNuclear scan 562
Contraindications 562
Interfering factors 562
Procedure and patient care 562
During 562
After 563
Abnormal findings 563
lumbar puncture and cerebrospinal fluid\rexamination (LP and CSF examination, Spinal tap,\rCerebrospinal fluid analysis) 564
Type of test Fluid analysis 564
Pressure 565
Color 565
Blood 565
Cells 566
Culture and sensitivity 566
Protein 566
Glucose 566
Chloride 566
Lactic dehydrogenase 567
Lactic acid 567
Cytology 567
Tumor markers 567
Serology for syphilis 567
Glutamine 567
C-reactive protein 567
Contraindications 568
Potential complications 568
Procedure and patient care 568
During 568
After 570
Abnormal findings 570
lung biopsy 572
Type of test Microscopic examination of tissue 572
Contraindications 572
Potential complications 572
Procedure and patient care 572
During 572
Transbronchial lung biopsy 573
Transbronchial needle aspiration 573
Transbronchial brushing 574
Percutaneous needle biopsy 574
Open lung biopsy 574
Thoracoscopic lung biopsy 574
After 574
Abnormal findings 575
lung cancer molecular testing (AKT1, ALK, BRAF, Epidermal Growth Factor [EGFR], HER2, KRAS, MEK1, MET, NRAS, PIK3CA, RET, and ROS1) 576
Type of test Microscopic examination 576
Procedure and patient care 576
During 577
After 577
Abnormal findings 577
lung scan (Ventilation/perfusion scanning [VPS], Pulmonary scintiphotography, scan) 578
Type of test Nuclear scan 578
Contraindications 579
Interfering factors 579
Procedure and patient care 579
During 579
Ventilation scan 579
Perfusion scan 579
After 580
Abnormal findings 580
luteinizing hormone (LH assay, Lutropin) and follicle-stimulating\rhormone (FSH) assay 581
Type of test Blood 581
Interfering factors 582
Procedure and patient care 582
Abnormal findings 582
lyme disease test 583
Type of test Blood 583
Normal findings 583
Western blot 583
Test explanation and related physiology 583
Interfering factors 584
Procedure and patient care 584
Abnormal findings 584
M 585
magnesium 585
Possible critical values 585
Interfering factors 585
Procedure and patient care 585
Abnormal findings 586
magnetic resonance imaging (MRI, Nuclear magnetic resonance imaging [NMRI]) 587
Type of test Magnetic field study 587
Potential complications 590
Contraindications 590
Interfering factors 590
Procedure and patient care 590
During 591
After 592
Abnormal findings 592
Brain 592
Heart 592
Other 592
mammography (Mammogram) 594
Type of test X-ray 594
Contraindications 595
Interfering factors 595
Procedure and patient care 597
During 597
After 598
Abnormal findings 598
maternal screen testing (Maternal triple screen, Maternal quadruple screen) 599
Type of test Blood or urine 599
Procedure and patient care 601
During 601
After 601
Abnormal findingsPositive screening tests (trisomy 21, trisomy 18, neural tube defects, abdominal wall defects) 601
measles rubeola antibody 603
Type of test Blood 603
N 622
natriuretic peptides (Atrial natriuretic peptide [ANP], Brain natriuretic peptide [BNP], N-terminal fragment of pro–brain [B-type] natriuretic peptide [NT–pro-BNP], C-type natriuretic peptide [CNP], Ventricular natriuretic peptide, CHF peptides) 622
Interfering factors 623
Procedure and patient care 623
Abnormal findings 623
neuron-specific enolase (NSE) 624
Type of test Blood 624
Procedure and patient care 624
Abnormal findings 624
neutrophil antibody screen (Granulocyte antibodies, Polymorphonucleocyte\rantibodies [PMN ab], Antigranulocyte antibodies, Antineutrophil antibodies, Neutrophil antibodies, Leukoagglutinin) 625
Type of test Blood 625
Interfering factors 625
Procedure and patient care 625
Abnormal findings 625
neutrophil gelatinase–associated lipocalin (NGAL, Lipocalin-2) 626
Type of test Blood 626
Procedure and patient care 626
Abnormal findings 627
newborn metabolic screening 628
Type of test Blood 628
Possible critical values 628
Interfering factors 631
Procedure and patient care 631
During 631
After 631
Abnormal findings 631
nicotine and metabolites (Nicotine, Cotinine, 3-Hydroxy Cotinine,\rNornicotine, Anabasine) 632
Type of test Urine/blood 632
Urine 632
Serum 632
Test explanation and related physiology 632
Interfering factors 634
Procedure and patient care 634
Before 634
During 634
Blood 634
Urine 634
Saliva 634
After 634
Abnormal finding 634
noninvasive prenatal testing (NIPT) 635
Type of test Blood 635
Interfering factors 635
Procedure and patient care 636
Abnormal findings 636
5′-nucleotidase 637
Type of test Blood 637
Normal findings 637
Test explanation and related physiology 637
Interfering factors 637
Procedure and patient care 637
Abnormal findings 637
O 638
obstruction series 638
Contraindications 639
Interfering factors 639
Procedure and patient care 639
During 639
After 639
Abnormal findings 639
octreotide scan (Carcinoid nuclear scan, Neuroendocrine\rnuclear scan) 640
Type of test Nuclear scan 640
Contraindications 640
Interfering factors 640
Procedure and patient care 640
During 641
After 641
Abnormal findings 641
osmolality, blood (Serum osmolality) 642
Type of test Blood 642
Possible critical values 642
Interfering factors 643
Procedure and patient care 643
Abnormal findings 643
osmolality, urine (Urine osmolality) 644
Type of test Urine 644
Procedure and patient care 645
Abnormal findings 645
oximetry (Pulse oximetry, Oxygen saturation) 646
Type of test Photodiagnostic 646
Normal findings 646
≤75% 646
Test explanation and related physiology 646
Procedure and patient care 646
During 647
After 647
Abnormal findings 647
P 648
pancreatic enzymes (Pancreatic secretory test, Amylase,Lipase, Trypsin, Chymotrypsin) 648
Procedure and patient care 649
Before 649
During 649
After 649
Abnormal findings 650
pancreatobiliary fish testing 651
Type of test Microscopic examination 651
Contraindications 651
Potential complications 651
Interfering factors 651
Procedure and patient care 651
During 652
After 652
Abnormal findings 652
Papanicolaou smear (Pap smear, Pap test, Cytologic test for cancer, Liquid-based cervical cytology [LBCC], ThinPrep) 653
Type of test Microscopic examination 653
Contraindications 654
Interfering factors 654
Procedure and patient care 654
During 655
After 655
Abnormal findings 656
paracentesis (Peritoneal fluid analysis, Ascitic fluid cytology, Peritoneal tap) 657
Type of test Fluid analysis 657
Contraindications 658
Potential complications 658
Procedure and patient care 658
During 659
After 659
Abnormal findings 659
parathyroid hormone (PTH, Parathormone) 661
Type of test Blood 661
Interfering factors 661
Procedure and patient care 661
Abnormal findings 662
parathyroid scan (Parathyroid scintigraphy) 663
Type of test Nuclear medicine 663
Contraindications 663
Procedure and patient care 663
During 663
After 664
Abnormal findings 664
partial thromboplastin time, activated (APTT, Partial thromboplastin time [PTT]) 665
Type of test Blood 665
Possible critical values 665
Interfering factors 666
Procedure and patient care 666
Abnormal findings 667
parvovirus B19 antibody 668
Type of test Blood 668
Procedure and patient care 668
Abnormal findings 668
pelvic ultrasonography (Pelvic ultrasonography in pregnancy, Obstetric ultrasonography, Vaginal ultrasound) 669
Type of test Ultrasound 669
Contraindications 671
Interfering factors 671
Procedure and patient care 671
During 671
After 671
Abnormal findings 671
pepsinogen 672
Type of test Blood/urine 672
Procedure and patient care 672
Abnormal findings 672
pericardiocentesis 673
Type of test Fluid analysis 673
Contraindications 673
Potential complications 673
Procedure and patient care 673
During 674
After 675
Abnormal findings 675
pheochromocytoma suppression and provocative testing (Clonidine suppression test [CST], Glucagon stimulation test) 676
Type of test Blood 676
Contraindications 676
Potential complications 676
Interfering factors 676
Procedure and patient care 677
During 677
Glucagon provocative test 677
Clonidine suppression test 677
After 677
Abnormal findings 677
phosphate (PO4, Phosphorus [P]) 678
Type of test Blood 678
Possible critical values 678
Interfering factors 679
Procedure and patient care 679
Abnormal findings 679
PI-linked antigen (Phosphatidylinositol antigen) 680
Type of test Blood 680
Procedure and patient care 680
Abnormal findings 680
placental growth factor (PGF) 681
Type of test Blood 681
Procedure and patient care 681
Abnormal findings 681
plasminogen (Fibrinolysin) 682
Type of testBlood 682
Interfering factors 682
Procedure and patient care 682
Abnormal findings 682
plasminogen activator inhibitor 1 (PAI-1) 683
Type of test Blood 683
Interfering factors 683
Procedure and patient care 683
Abnormal findings 684
platelet aggregation test (Ristocetin test) 685
Type of test Blood 685
Interfering factors 685
Procedure and patient care 685
Abnormal findings 686
platelet antibody detection (Antiplatelet antibody detection) 687
Type of test Blood 687
Interfering factors 688
Procedure and patient care 688
Abnormal findings 688
platelet count (Thrombocyte count) 689
Type of test Blood 689
Possible critical values 689
Interfering factors 690
Procedure and patient care 690
Abnormal findings 691
platelet function assay (Platelet closure time, PCT, Aspirin resistance tests, Bleeding time [BT], 11-Dehydro-thromboxane B2) 692
Type of test Blood, urine 692
Interfering factors 693
Procedure and patient care 693
Abnormal findings 694
platelet volume, mean (Mean platelet volume [MPV]) 695
Type of testBlood 695
Procedure and patient care 695
Abnormal findings 695
plethysmography, arterial (Ankle-brachial index [ABI]) 696
Type of test Manometric 696
Interfering factors 697
Procedure and patient care 697
During 697
After 697
Abnormal findings 697
pleural biopsy 698
Type of test Microscopic examination of tissue 698
Contraindications 698
Potential complications 698
Procedure and patient care 698
During 698
After 699
Abnormal findings 699
porphyrins and porphobilinogens 700
Type of test Urine (fresh and 24-hour) 700
Interfering factors 700
Procedure and patient care 701
Abnormal findings 701
positron emission tomography (PET scan) 702
Type of test Nuclear scan, x-ray 702
Neurology 702
Cardiology 703
Oncology 703
Bone 704
Interfering factors 704
Procedure and patient care 705
During 705
After 706
Abnormal findings 706
potassium, blood (K) 707
Type of test Blood 707
Possible critical values 707
Interfering factors 708
Procedure and patient care 708
Abnormal findings 709
potassium, urine (K) 710
Type of test Urine (24-hour) 710
Interfering factors 710
Procedure and patient care 710
Abnormal findings 710
prealbumin (PAB, Thyroxine-binding prealbumin [TBPA], Thyretin, Transthyretin) 711
Type of test Blood; urine (24-hour); cerebrospinal fluid (CSF) analysis 711
Possible critical values 711
Interfering factors 712
Procedure and patient care 712
Abnormal findings 712
pregnancy-associated plasma protein-A (PAPP-A) 713
Type of test Blood 713
Interfering factors 713
Procedure and patient care 713
Abnormal findings 713
pregnanediol 714
Type of test Urine (24-hour) 714
Interfering factors 714
Procedure and patient care 715
Abnormal findings 715
progesterone assay 716
Type of test Blood 716
Interfering factors 716
Procedure and patient care 717
Abnormal findings 717
progesterone receptor assay (PR assay, PRA, PgR) 718
Type of test Tumor-specimen analysis 718
Interfering factors 718
Procedure and patient care 718
During 719
After 719
Abnormal findings 719
prolactin levels (PRLs) 720
Type of test Blood 720
Interfering factors 720
Procedure and patient care 721
Abnormal findings 721
prostascint scan (Radioimmunoscintigraphy [RIS]) 722
Type of test Nuclear scan 722
Contraindications 722
Interfering factors 722
Procedure and patient care 722
During 722
After 723
Abnormal findings 723
prostate/rectal sonogram (Ultrasound prostate) 724
Type of test Ultrasound 724
Contraindications 725
Interfering factors 725
Procedure and patient care 725
During 725
After 725
Abnormal findings 725
prostate-specific antigen (PSA), prostate cancer gene 3 (PCA3), MI-prostate score (MiPS) 726
Type of test Blood 726
Interfering factors 727
Procedure and patient care 727
Abnormal findings 728
protein (Protein electrophoresis, Immunofixation electrophoresis [IFE], Serum protein electrophoresis [SPEP], Albumin, Globulin, Total protein) 729
Type of test Blood; urine 729
Interfering factors 731
Procedure and patient care 732
During 732
Blood 732
Urine 732
After 732
Abnormal findings 732
protein C, protein S 733
Type of test Blood 733
Interfering factors 733
Procedure and patient care 733
Abnormal findings 734
prothrombin time (PT, Protime, International normalized ratio [INR]) 735
Possible critical values 735
Interfering factors 737
Procedure and patient care 737
Abnormal findings 738
pulmonary angiography (Pulmonary arteriography) 739
Type of test X-ray with contrast dye 739
Contraindications 739
Potential complications 739
Procedure and patient care 739
During 740
After 740
Abnormal findings 740
pulmonary function tests (PFTs) 741
Contraindications 744
Procedure and patient care 744
During 744
Spirometry and airflow rates 744
Gas exchange/diffusing capacity of the lung (DL) 745
Inhalation tests (bronchial provocation studies) 745
After 745
Abnormal findings 745
pyelography (Intravenous pyelography [IVP], Excretory urography\r[EUG], Intravenous urography [IUG, IVU], Retrograde pyelography, Antegrade pyelography) 746
Type of test X-ray with contrast dye 746
Normal findings 746
Test explanation and related physiology 746
Contraindications 747
Potential complications 747
Interfering factors 748
Procedure and patient care 748
During 749
After 750
Abnormal findings 750
R 751
rabies-neutralizing antibody test 751
Procedure and patient care 751
Abnormal findings 751
red blood cell count (RBC count, Erythrocyte count) 752
Type of test Blood 752
Interfering factors 752
Procedure and patient care 753
Abnormal findings 753
red blood cell indices (RBC indices, Blood indices) 754
Type of test Blood 754
Mean corpuscular volume 754
Mean corpuscular hemoglobin 755
Mean corpuscular hemoglobin concentration 756
Red blood cell distribution width 756
Interfering factors 756
Procedure and patient care 756
Abnormal findings 757
renal biopsy (Kidney biopsy) 758
Type of test Microscopic examination of tissue 758
Contraindications 759
Potential complications 759
Procedure and patient care 759
During 759
After 760
Abnormal findings 760
renal scanning (Kidney scan, Radiorenography, Radionuclide renal imaging, Nuclear imaging of the kidney, DSMA renal scan, DTPA renal scan, Captopril renal scan) 761
Type of test Nuclear scan 761
Renal blood flow (perfusion) scan 761
Renal structural scan 761
Renal function scan (Renogram) 762
Renal hypertension scan 762
Renal obstruction scan 762
Contraindications 762
Procedure and patient care 762
During 763
After 764
Abnormal findings 764
renin assay, plasma (Plasma renin activity [PRA], Plasma renin concentration [PRC]) 765
Type of test Blood 765
Plasma renin assay 765
Renal vein 765
Test explanation and related physiology 765
Contraindications 767
Potential complications 767
Interfering factors 767
Procedure and patient care 768
During 768
After 768
Abnormal findings 769
reticulocyte count (Retic count) 770
Type of test Blood 770
Interfering factors 770
Procedure and patient care 771
Abnormal findings 771
rheumatoid factor (RF) 772
Type of test Blood 772
Interfering factors 772
Procedure and patient care 773
Abnormal findings 773
ribosome P antibodies (Ribosomal P Ab, Anti–ribosome P antibodies) 774
Type of test Blood 774
Procedure and patient care 774
Abnormal findings 774
rubella antibody test (German measles test) 775
Type of test Blood 775
Normal findings 775
Possible critical values 775
Test explanation and related physiology 775
Procedure and patient care 776
Abnormal findings 776
S 777
salivary gland nuclear imaging (Parotid gland nuclear imaging) 777
Contraindications 777
Interfering factors 777
Procedure and patient care 777
Before 777
During 778
Abnormal findings 778
SARS viral testing 779
Type of test Blood; fluid analysis 779
Procedure and patient care 779
During 779
After 780
Abnormal findings 780
scrotal ultrasound (Ultrasound of testes) 781
Type of test Ultrasound 781
Procedure and patient care 782
During 782
After 782
Abnormal findings 782
semen analysis (Sperm count, Sperm examination) 783
Type of test Fluid analysis 783
Interfering factors 784
Procedure and patient care 784
During 785
After 785
Abnormal findings 785
sentinel lymph node biopsy (SLNB, Lymphoscintigraphy) 786
Type of test Nuclear scan 786
Contraindications 786
Potential complications 786
Procedure and patient care 786
During 786
After 787
Abnormal findings 787
serotonin (5-hydroxytryptamine, 5-HT) and chromogranin A 788
Type of test Blood 788
Interfering factors 789
Procedure and patient care 789
Abnormal findings 789
sexual assault testing (rape testing) 790
Type of test Blood; fluid analysis 790
Contraindications 791
Interfering factors 791
Procedure and patient care 791
During 792
After 792
Abnormal findings 792
sexually transmitted disease testing (STD testing) 793
Type of test Microscopic examination 793
Interfering factors 795
Procedure and patient care 795
During 795
Cervical culture 795
Anal canal culture 795
Oropharyngeal culture 795
Urethral culture 796
Urine culture 796
Pap smear ThinPrep See p. 653 796
After 796
Abnormal findings 797
sialography 798
Type of test X-ray 798
Contraindications 798
Potential complications 798
Procedure and patient care 798
During 798
After 799
Abnormal findings 799
sickle cell screen (Sickledex, Hemoglobin [Hgb] S test) 800
Type of test Blood 800
Interfering factors 800
Procedure and patient care 800
Abnormal findings 801
sigmoidoscopy (Proctoscopy, Anoscopy) 802
Type of test Endoscopy 802
Contraindications 802
Potential complications 802
Interfering factors 802
Procedure and patient care 802
During 802
After 803
Abnormal findings 803
Sims-Huhner test (Postcoital test, Postcoital cervical mucus test, Cervical mucus sperm penetration test) 804
Type of testFluid analysis 804
Procedure and patient care 804
During 805
After 805
Abnormal findings 805
skin biopsy (Cutaneous immunofluorescence biopsy, Skin biopsy antibodies, Skin immunohistopathology, Direct immunofluorescence antibody test) 806
Type of test Microscopic examination 806
Procedure and patient care 806
During 806
After 806
Abnormal findings 806
skull x-ray 807
Type of test X-ray 807
Procedure and patient care 807
During 807
After 807
Abnormal findings 807
sleep studies (Polysomnography [PSG]) 808
Type of test Electrodiagnostic; various 808
Interfering factors 810
Procedure and patient care 810
During 810
Multiple sleep latency testing 811
Multiple wake testing 811
After 811
Abnormal findings 811
small bowel follow-through (SBF, Small bowel enema) 812
Type of test X-ray with contrast dye 812
Contraindications 812
Potential complications 812
Interfering factors 813
Procedure and patient care 813
During 813
Small bowel enema 813
After 814
Abnormal findings 814
Type of testBlood 815
Possible critical values 815
Interfering factors 815
Procedure and patient care 816
Abnormal findings 816
Type of testUrine (24-hour) 817
Interfering factors 817
Procedure and patient care 818
Abnormal findings 818
spinal x-ray (Cervical, thoracic, lumbar, sacral, and coccygeal x-ray studies) 819
Type of test X-ray 819
Contraindications 819
Procedure and patient care 819
During 819
After 820
Abnormal findings 820
sputum culture and sensitivity (C&S, Culture and Gram stain) 821
Type of test Sputum 821
Procedure and patient care 821
During 822
After 822
Abnormal findings 822
sputum cytology 823
Type of test Sputum 823
Procedure and patient care 823
During 823
After 823
Abnormal findings 823
stool culture (Stool for culture and sensitivity [C&S], Stool for ova and parasites [O&P]) 824
Type of test Stool 824
Interfering factors 824
Procedure and patient care 824
During 825
Tape test 825
After 825
Abnormal findings 825
stool cancer screening (stool for occult blood, Stool for OB, Fecal occult blood test [FOBT], Fecal immunotest [FIT], DNA stool sample) 826
Type of test Stool 826
Interfering factors 827
Procedure and patient care 827
During 828
Hemoccult slide test 828
Tablet test 828
DNA Home Test 828
After 828
Abnormal findings 828
Streptococcus serologic testing (Antistreptolysin O titer [ASO], Antideoxyribonuclease-B titer, [Anti-DNase-B, ADNase-B, ADB], Streptococcus group B antigen detection, Streptozyme) 829
Type of test Blood; CSF 829
Interfering factors 830
Procedure and patient care 830
Abnormal findings 830
substance abuse testing (Urine drug testing, Drug screening, Toxicology screening) 831
Type of test Urine; blood; various 831
Interfering factors 832
Procedure and patient care 833
During 833
After 833
Abnormal findings 833
swallowing examination (Videofluoroscopy swallowing examination) 834
Type of test X-ray with contrast dye 834
Contraindications 834
Procedure and patient care 834
During 835
After 835
Abnormal findings 835
sweat electrolytes test (lontophoretic sweat test) 836
Type of test Fluid analysis 836
Procedure and patient care 836
During 836
After 837
Abnormal findings 837
syphilis detection test (Serologic test for syphilis [STS], Venereal\rDisease Research Laboratory [VDRL], Rapid plasma reagin [RPR], Fluorescent treponemal antibody test [FTA]) 838
Type of test Blood 838
Normal findings 838
Test explanation and related physiology 838
Interfering factors 839
Procedure and patient care 839
Abnormal findings 839
T 840
testosterone (Dihydrotestosterone [DHT]) 840
Type of test Blood 840
Interfering factors 841
Procedure and patient care 841
Abnormal findings 842
thoracentesis and pleural fluid analysis (Pleural tap) 843
Type of test Fluid analysis 843
Gross appearance 843
Cell counts 844
Protein content 844
Lactic dehydrogenase 845
Glucose 845
Amylase 845
Triglyceride 845
Gram stain and bacteriologic culture 845
Cultures for Mycobacterium tuberculosis and fungus 845
Cytology 846
Carcinoembryonic antigen 846
Special tests 846
Contraindications 846
Potential complications 846
Procedure and patient care 846
During 847
After 847
Abnormal findings 848
thoracoscopy 849
Type of test Endoscopy 849
Contraindications 849
Potential complications 849
Procedure and patient care 849
During 849
After 850
Abnormal findings 850
throat and nose cultures 851
Type of test Microscopic examination 851
Interfering factors 852
Procedure and patient care 852
During 852
After 852
Abnormal findings 852
thromboelastography (Thromboelastometry) 853
Type of test Blood 853
Test explanation and related physiology 853
Interfering factors 853
Procedure and patient care 854
Abnormal findings 855
thrombosis indicators\rfibrin monomers (Fibrin degradation products [FDPs], Fibrin split products [FSPs])\rfibrinopeptide A (FPA)\rprothrombin fragment (F1 + 2) 856
Type of test Blood 856
Possible critical values 856
Interfering factors 857
Procedure and patient care 857
Abnormal findings 857
thyroglobulin (Tg, Thyrogen-stimulated thyroglobulin) 858
Type of test Blood 858
Interfering factors 859
Procedure and patient care 859
Abnormal findings 859
thyroid cancer genomic testing (Gene Expression Classifier\r(GEC), Medullary Thyroid Malignancy Classifier [MTC], BRAF gene) 860
Type of test Microscopic examination 861
Procedure and patient care 861
During 861
After 861
Abnormal findings 861
thyroid fine needle aspiration biopsy (FNAB,\rSkinny-needle thyroid biopsy, Fine needle aspiration [FNA]) 862
Type of test Microscopic examination of tissue 862
Contraindications 862
Potential complications 863
Procedure and patient care 863
During 863
After 863
Abnormal findings 863
thyroid scanning (Thyroid scintiscan) 864
Type of test Nuclear scan 864
Contraindications 865
Potential complications 865
Interfering factors 865
Procedure and patient care 865
During 865
After 866
Abnormal findings 866
thyroid-stimulating hormone (TSH, Thyrotropin, TRH stimulation\rtest) 867
Type of test Blood 867
Interfering factors 867
Procedure and patient care 868
Abnormal findings 868
thyroid-stimulating hormone stimulation test (TSH stimulation test) 869
Type of test Blood 869
Procedure and patient care 869
Abnormal findings 869
thyroid-stimulating immunoglobulins (TSIs, Long-acting thyroid stimulator [LATS], Thyroid-binding inhibitory immunoglobulin [TBII], Thyrotropin receptor antibody, Thyroid-stimulating hormone receptor [TSHR] antibodies) 870
Type of test Blood 870
Interfering factors 870
Procedure and patient care 870
Abnormal findings 871
thyroid ultrasound (Thyroid echogram, Thyroid sonogram) 872
Type of test Ultrasound 872
Procedure and patient care 872
During 872
After 872
Abnormal findings 872
thyrotropin-releasing hormone stimulation test (TRH stimulation test, Thyrotropin-releasing factor stimulation test [TRF stimulation test]) 873
Type of test Blood 873
Interfering factors 873
Procedure and patient care 874
Abnormal findings 874
thyroxine, total and free (T4, Thyroxine screen, FT4) 875
Type of testBlood 875
Interfering factors 876
Procedure and patient care 876
Abnormal findings 877
thyroxine-binding globulin (TBG, Thyroid-binding globulin) 878
Type of test Blood 878
Interfering factors 878
Procedure and patient care 878
Abnormal findings 879
TORCH test 880
total blood volume (TBV, Red blood cell [RBC] volume) 881
Type of test Nuclear scan 881
Procedure and patient care 882
Before 882
During 882
After 882
Abnormal findings 882
toxoplasmosis antibody titer 883
Type of test Blood 883
Procedure and patient care 883
Abnormal findings 883
transesophageal echocardiography (TEE) 884
Type of test Endoscopy/ultrasound 884
Contraindications 884
Potential complications 885
Procedure and patient care 885
During 885
After 886
Abnormal findings 886
transferrin receptor (TfR) assay 887
Type of test Blood 887
Interfering factors 887
Procedure and patient care 888
Abnormal findings 888
triglycerides (TGs) 889
Type of test Blood 889
Possible critical values 889
Interfering factors 889
Procedure and patient care 889
Abnormal findings 890
triiodothyronine (T3 radioimmunoassay) 891
Type of test Blood 891
Interfering factors 891
Procedure and patient care 892
Abnormal findings 892
troponins (Cardiac-specific troponin T [cTnT], Cardiac-specific troponin I [cTnI]) 893
Type of test Blood 893
Interfering factors 894
Procedure and patient care 894
Abnormal findings 895
tuberculin skin test (TST, Tuberculin test, Mantoux test, Purified\rprotein derivative [PPD] test) 896
Type of test Skin 896
Contraindications 896
Procedure and patient care 897
During 897
After 897
Abnormal findings 897
tuberculosis culture (TB culture, Acid-fast bacillus [AFB] smear) 898
Type of test Microbiology culture 898
Interfering factors 899
Procedure and patient care 899
During 899
After 899
Abnormal findings 899
tuberculosis testing (TB testing, Interferon gamma release assay [IGRA, T-Spot.TB], QuantiFERON-TB Gold [QFT, QFT-G, TB Gold test, TB blood test], Nucleic acid amplification for TB [NAAT], TB antibody) 900
Type of test Blood, sputum, fluid analysis 900
Normal findings 900
Interfering factors 901
Procedure and patient care 901
During 901
After 902
Abnormal finding 902
U 903
upper gastrointestinal x-ray study (Upper GI series, UGI) 903
Contraindications 903
Potential complications 904
Interfering factors 904
Procedure and patient care 904
Before 904
During 904
After 905
Abnormal findings 905
urea breath test (UBT, Helicobacter pylori breath test) 906
Type of test Other 906
Interfering factors 906
Procedure and patient care 907
During 907
After 907
Abnormal findings 907
urea nitrogen blood test (Blood urea nitrogen [BUN]) 908
Type of test Blood 908
Possible critical values 908
Interfering factors 908
Procedure and patient care 909
Abnormal findings 909
uric acid, blood, and urine 910
Type of test Blood; urine 910
Blood 910
Urine 910
Possible critical values 910
Interfering factors 911
Procedure and patient care 911
During 911
Blood 911
Urine 911
After 912
Blood 912
Urine 912
Abnormal findings 912
urinalysis (UA) 913
Type of test Urine 913
Appearance and color 914
Odor 914
pH 914
Protein 916
Glucose 917
Osmolality 917
Specific gravity 917
Leukocyte (WBC) esterase 919
Nitrites 919
Ketones 919
Bilirubin and urobilinogen 919
Crystals 919
Casts 919
Interfering factors 921
Appearance and color 921
Odor 921
pH 921
Protein 921
Specific gravity 921
Leukocyte esterase 921
Ketones 921
Bilirubin and urobilinogen 922
Crystals 922
WBCs 922
RBCs 922
Procedure and patient care 922
During 922
After 923
Abnormal findings 923
Appearance and color 923
Odor 923
pH 924
Protein 924
Glucose 924
Specific gravity 925
Leukocyte esterase 925
Nitrites 925
Ketones 925
Crystals 926
Granular casts 926
Fatty casts 926
Epithelial casts 926
Waxy casts 926
Hyaline casts 926
Red blood cells and casts 927
White blood cells and casts 927
urinary stone analysis (Renal calculus analysis) 928
Type of test Urine 928
Interfering factors 928
Procedure and patient care 928
During 929
After 929
Abnormal findings 929
urine culture and sensitivity (C&S) 930
Type of test Urine; microscopic 930
Interfering factors 930
Procedure and patient care 930
During 931
After 931
Abnormal findings 931
urine flow studies (Uroflowmetry, Urodynamic studies) 932
Type of test Urodynamic 932
Procedure and patient care 932
During 932
After 933
Abnormal findings 933
uroporphyrinogen-1-synthase 934
Type of test Blood 934
Normal findings 934
Test explanation and related physiology 934
Procedure and patient care 934
Abnormal findings 934
V 935
vanillylmandelic acid (VMA), homovanillic acid (HVA), and\rcatecholamines (Epinephrine, Norepinephrine, Metanephrine, Normetanephrine, Dopamine) 935
VMA 935
HVA 935
Catecholamines 935
Interfering factors 936
Procedure and patient care 937
Before 937
During 937
After 937
Abnormal findings 938
vascular ultrasound studies (Venous Doppler ultrasound, Venous duplex scan) 939
Type of test Ultrasound 939
Venous 939
Arterial 939
Test explanation and related physiology 939
Interfering factors 940
Procedure and patient care 940
During 940
Venous studies 940
Arterial studies 940
After 941
Abnormal findings 941
venography of lower extremities (Phlebography, Venogram) 942
Type of test X-ray with contrast dye 942
Contraindications 942
Potential complications 942
Procedure and patient care 943
During 943
After 943
Abnormal findings 943
viral cultures 944
Type of test Blood; urine; stool; throat; skin lesions 944
Interfering factors 945
Procedure and patient care 945
During 945
After 945
Abnormal findings 945
virus testing 946
Type of test Blood; miscellaneous 946
Interfering factors 946
Procedure and patient care 947
Abnormal findings 947
vitamin B12 (Cyanocobalamin) and methylmalonic acid (MMA) 948
Type of testBlood; urine 948
Procedure and patient care 948
Abnormal findings 949
vitamin D (25-hydroxy vitamin D2 and D3; 1,25-dihydroxyvitamin D [1,25(OH)2D]) 950
Type of test Blood 950
Normal findings 950
Test explanation and related physiology 950
Interfering factors 951
Procedure and patient care 951
Abnormal findings 952
W 953
white blood cell count and differential count\r(WBC and differential, Leukocyte count) 953
Total WBCs 953
Differential count 953
WBCs <2500 or >30,000/mm3 953
Interfering factors 955
Procedure and patient care 955
Abnormal findings 956
?Increased/decreased differential count 956
white blood cell scan (WBC scan, Inflammatory scan) 958
Type of testNuclear scan 958
Procedure and patient care 958
During 958
After 959
Abnormal findings 959
wound culture and sensitivity (C&S) 960
Type of test Microscopic examination 960
Normal findings 960
Test explanation and related physiology 960
Interfering factors 960
Procedure and patient care 960
During 960
After 961
Abnormal findings 961
D 962
d-xylose absorption test (Xylose tolerance test) 962
Contraindications 962
Interfering factors 962
Procedure and patient care 963
During 963
After 963
Abnormal findings 963
Z 964
zinc protoporphyrin (ZPP) 964
Test explanation and related physiology 964
Procedure and patient care 964
Abnormal findings 964
A - list of tests by body system 965
B - list of tests by type 977
C - disease and organ panels 988
D - symbols and units of measurement\r 992
bibliography 994
Index 998
A 998
B 1002
C 1005
D 1009
E 1011
F 1012
G 1014
H 1015
I 1019
J 1020
K 1020
L 1020
M 1022
N 1024
O 1026
P 1026
Q 1030
R 1031
S 1032
T 1035
U 1037
V 1038
W 1039
X 1039
Y 1040
Z 1040
abbreviations for diagnostic and laboratory tests ES3