Additional Information
Book Details
Abstract
The new edition of this ground-breaking text is an essential resource for the management of drugs during pregnancy, labour and the postnatal period. Fully updated in line with current midwifery practice, it includes new chapters on Disorders of the Immune System and Recreational Drugs, and expanded coverage of pain relief.
The new edition of this ground-breaking text is an essential resource for the management of drugs during pregnancy, labour and the postnatal period. Fully updated in line with current midwifery practice, it includes new chapters on Disorders of the Immune System and Recreational Drugs, and expanded coverage of pain relief.
SUE JORDAN is Reader in Nursing and Midwifery at the School of Health and Human Science at Swansea University, UK.
"I consider this an essential text for our pharmacology module in year 1. Affordable, accessible and facilitates the students' achievement of NMC Essential Skills cluster 5 (medicines management)" - Anne Lincoln, Lecturer, Florence Nightingale School of Nursing and Midwifery, King's College London, UK
"This is a very comprehensive text ideally suited to it's intended audience. The layout is clear and content well organized giving valuable information in a very readable format. A must for all students and practising midwives." - Kate Taylor, Senior Lecturer, School of Nursing, Midwifery and Pre-Hospital Emergency Care, University of Worcester, UK
"...well presented text that will see the students through not only the first year module but their 3 years and post qualification." - Ellen Kitson-Reynolds, Faculty of Health Sciences, University of Southampton, UK
Praise for the first edition:
'An excellent book, It is well written and readable. Contains excellent information and is well researched and referenced. The practice points/implications for practice and case studies are relevant and enhance the book. I will be strongly recommending it to the units as well as to students and qualified staff, Drs could also benefit from reading this. Well Done.
- Mrs V R Morse, School of Care Sciences, University of Glamorgan
'A much needed& long overdue text which focuses on pharmacology in the midwifery setting. Well laid out& easy to read. A must for every student& practising midwifery.'
- Mrs Glenys McGuire, Department of Midwifery, University of Huddersfield
'This is an excellent and very useful textbook. I was delighted to read through it - valuable contents.'
- Mrs Linda Javncey, Department of Nursing& Midwifery, University of Stirling
'Extensive evidence based resource that students can use from the beginning of their career right into practice'
- Mrs Maggie Prain, School of Women's Health Studies, UCE Birmingham
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Cover | Cove | ||
Contents | vii | ||
List of Implications for Practice | xiii | ||
List of Figures | xiv | ||
List of Tables | xv | ||
List of Boxes | xvi | ||
List of Contributors | xvii | ||
Foreword | xviii | ||
Preface | xix | ||
Acknowledgements | xxi | ||
Using this Book | xxii | ||
List of Abbreviations | xxiii | ||
Part I: Introduction to Pharmacology | 1 | ||
Introduction | 2 | ||
1 Principles of Pharmacology | 3 | ||
The evidence base for pharmacological interventions | 3 | ||
Drug therapy | 5 | ||
Conclusion | 31 | ||
Further reading | 32 | ||
2 Administration of Medicines | 39 | ||
Oral administration | 39 | ||
Buccal/sublingual administration | 40 | ||
Rectal administration | 40 | ||
Vaginal administration | 42 | ||
Injections | 42 | ||
Intravenous administration | 45 | ||
Epidural and intrathecal administration | 51 | ||
Conclusion | 61 | ||
Further reading | 61 | ||
3 Law, Medicines and the Midwife | 62 | ||
Introduction | 62 | ||
Accountability | 63 | ||
The legal regulation of medicines | 64 | ||
Administration of prescription only medicine | 65 | ||
Alternatives to prescriptions for the supply and administration of medicines | 68 | ||
Professional requirements | 72 | ||
Civil liability | 73 | ||
Conclusion | 74 | ||
Further reading | 74 | ||
Part II: Drugs in Labour | 75 | ||
Introduction | 76 | ||
4 Pain relief | 77 | ||
Pathophysiology of pain | 77 | ||
Inhalation analgesia | 79 | ||
Opioids | 87 | ||
Local anaesthetics | 106 | ||
Summary: pain relief in labour | 122 | ||
Pain relief in pregnancy and the puerperium: NSAIDs and paracetamol | 124 | ||
Further reading | 130 | ||
5 Antiemetics | 131 | ||
Physiology of nausea and vomiting | 131 | ||
Emesis in early pregnancy | 133 | ||
Pharmacological management of emesis | 134 | ||
Dopamine (D2) antagonists (mainly metoclopramide and prochlorperazine) | 135 | ||
Antihistamines | 141 | ||
Other antiemetics | 144 | ||
Conclusion | 147 | ||
Further reading | 147 | ||
6 Drugs Increasing Uterine Contractility: Uterotonics (Oxytocics) | 148 | ||
Uterine contractility | 148 | ||
Uterotonics (oxytocics) | 149 | ||
Prostaglandins | 150 | ||
Oxytocin | 158 | ||
Newer drugs | 169 | ||
Summary: induction and augmentation of labour | 170 | ||
Ergometrine | 171 | ||
Further reading | 177 | ||
7 Drugs Decreasing Uterine Contractility/Tocolytics | 178 | ||
Calcium channel blockers (mainly nifedipine) | 179 | ||
Atosiban | 184 | ||
Beta2 adrenoceptor agonists | 184 | ||
Corticosteroids and tocolysis | 190 | ||
Further reading | 195 | ||
Part III: Disordered Physiology in Childbirth | 197 | ||
Introduction | 198 | ||
8 Drugs Affecting the Coagulation Process | 199 | ||
Haemostasis | 199 | ||
Anticoagulants | 202 | ||
Vitamin K1 (phytomenadione) | 216 | ||
Further reading | 220 | ||
9 Cardiovascular Disorders in Pregnancy | 221 | ||
Blood pressure in pregnancy | 221 | ||
Pre-eclampsia and eclampsia | 222 | ||
Magnesium sulphate | 227 | ||
Pregnancy-induced hypertension and hypertension in pregnancy | 237 | ||
Drugs used in hypertensive emergencies | 243 | ||
Other cardiovascular conditions | 245 | ||
Further reading | 246 | ||
Part IV: Drugs in Pregnancy | 247 | ||
Introduction | 248 | ||
10 Nutritional Supplements in Pregnancy: Iron and Folic Acid | 249 | ||
Nutrition in pregnancy | 249 | ||
Iron | 250 | ||
Folic acid | 259 | ||
Further reading | 262 | ||
11 Management of Gastric Acidity in Pregnancy | 263 | ||
Causes and management of heartburn in pregnancy | 263 | ||
Antacids | 265 | ||
Chelates and complexes (sucralfate) | 267 | ||
Acid suppressants | 268 | ||
Conclusion | 270 | ||
Further reading | 270 | ||
12 Laxatives in Pregnancy and the Puerperium | 271 | ||
Constipation | 271 | ||
Laxatives | 276 | ||
Conclusion | 283 | ||
Further reading | 283 | ||
13 Antimicrobial Agents | 284 | ||
Pathogenic and beneficial microorganisms | 285 | ||
Antimicrobials in pregnancy | 285 | ||
Antibacterials and their actions | 287 | ||
Antifungals and their actions | 291 | ||
Antivirals and their actions | 293 | ||
Antiprotozoals and their actions | 294 | ||
Antihelminthics and their actions | 295 | ||
Insecticides and their actions | 296 | ||
How the body handles antimicrobials | 297 | ||
Adverse effects of antimicrobials | 300 | ||
Conclusion | 305 | ||
Further reading | 307 | ||
14 Drugs and the Immune System | 308 | ||
The immune system | 308 | ||
Hypersensitivity or allergic responses | 310 | ||
Blood groups | 310 | ||
Rhesus incompatibility | 311 | ||
The immune system in pregnancy | 316 | ||
Allergic disorders in pregnancy | 318 | ||
Development of the immune system | 320 | ||
Conclusion | 322 | ||
Further reading | 322 | ||
Part V: Pregnancy in Women with Pre-existing Disease | 323 | ||
Introduction | 324 | ||
Further reading | 324 | ||
15 Asthma in Pregnancy | 325 | ||
Asthma | 325 | ||
Drugs used in asthma | 329 | ||
Conclusion | 337 | ||
Further reading | 337 | ||
16 Diabetes Mellitus and Pregnancy | 338 | ||
Diabetes | 338 | ||
Insulin needs in pregnancy | 339 | ||
Insulin | 342 | ||
Labour and diabetes | 348 | ||
Breastfeeding and diabetes | 348 | ||
Oral hypoglycaemics | 348 | ||
Conclusion | 351 | ||
Further reading | 351 | ||
17 Thyroid Disorders in Pregnancy | 352 | ||
Thyroid hormones | 352 | ||
Thyroid function tests (TFTs) in pregnancy | 353 | ||
Hyperthyroidism | 355 | ||
Hypothyroidism | 356 | ||
Other endocrine disorders | 360 | ||
Further reading | 360 | ||
18 Epilepsy in Pregnancy | 361 | ||
Epilepsy | 362 | ||
Effect of pregnancy on epilepsy | 362 | ||
Effect of epilepsy on pregnancy | 363 | ||
Antiepileptic drugs (AEDs) and congenital anomalies | 363 | ||
Antiepileptic drugs (AEDs) | 366 | ||
First-generation (older) antiepileptic drugs (AEDs) | 367 | ||
Newer antiepileptic drugs (AEDs) | 371 | ||
Management of epilepsy in pregnancy | 374 | ||
Conclusion | 376 | ||
Further reading | 376 | ||
19 Drugs and Mental Health | 377 | ||
Childbirth and mental health problems/mental illness | 377 | ||
Drugs prescribed for mental illness | 379 | ||
Selective serotonin reuptake inhibitors (SSRIs) | 379 | ||
Tricyclic antidepressants (TCAs) | 386 | ||
Antipsychotics | 387 | ||
Anxiolytics | 391 | ||
Lithium therapy | 391 | ||
Conclusion | 393 | ||
Further reading | 394 | ||
20 Recreational Drugs | 395 | ||
Alcohol/ethanol | 396 | ||
Caffeine | 401 | ||
Cigarettes | 403 | ||
Cannabis | 405 | ||
Recreational opioids | 407 | ||
Stimulants | 411 | ||
Conclusion | 416 | ||
Further reading | 416 | ||
Appendix I Quick Reference for Major Drug Groups/Drugs | 417 | ||
Appendix II Glossary | 436 | ||
References | 441 | ||
Index | 477 |