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The Biology of Psychological Disorders

The Biology of Psychological Disorders

David Linden

(2011)

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Book Details

Abstract

Psychological disorders – their origins, clinical symptoms and treatment – have a central place in contemporary public health debate. Understanding how disruptions in the brain's biological mechanisms can influence our thoughts, feelings and actions is one of the most exciting challenges for psychologists in the twenty-first century.

The Biology of Psychological Disorders is an authoritative account of some of the most prevalent psychological disorders, from schizophrenia, depression, mania and substance abuse to disorders of childhood, adolescence and ageing. Detailed and engaging coverage of these disorders is combined with a comprehensive grounding in the fundamentals of neuroscience and the principles of psychopharmacology that underpin their treatment. Drawing on the fields of psychology, psychiatry, neuroscience and biology, this highly relevant text is an invaluable resource for students of biological psychology and psychopharmacology, trainee psychiatrists and anyone interested in understanding, researching and treating psychological disorders.
"A great resource that addresses some of the key questions in our discipline, this timely book combines a foundation in the basic principles of biological psychology with an integrative, critical evaluation of the neurobiological underpinnings of a broad range of psychological disorders." – Dr Alexander Sumich, Division of Psychology, Nottingham Trent University, UK

"This textbook challenges mental health professionals to reclaim the lost territory of neuropsychiatry. Linden presents both basic and more advanced concepts of contemporary neuroscience, resisting the tendency to leave the study of the brain to
neurology. Every student of brain and behaviour will appreciate this resource." – Dr Stephan Heckers, Chair and Professor of the Department of Psychiatry, Vanderbilt University, USA

"This timely and well researched text is an engaging and thorough exploration of the biological basis of psychological disorders and their pharmacological treatment. It will be a superb source for those with an interest in medicine, neuroscience, biopsychology and psychopharmacology, and essential reading for undergraduate and postgraduate students, teachers and clinicians." – Dr Nikola Bridges, School of Psychology, University of Central Lancashire, UK


An innovative, clearly structured and authoritative book that presents the latest research on the biological roots of a number of psychological disorders, from dementia to sleep disorders
David Linden is Professor of Translational Neuroscience at the School of Psychology and the Department of Psychological Medicine and Neurology of Cardiff University, UK. He is also an Honorary Consultant Psychiatrist at the same institution, with a special interest in Neuropsychiatry.
 

Table of Contents

Section Title Page Action Price
Cover\r Cover
Half-Title\r i
Title\r iii
Copyright\r iv
Brief Contents v
Preface xix
Introduction xxi
PART I BASIC NEUROSCIENCE AND RESEARCH METHODS 1
1 Neuroanatomy 3
2 Neurophysiology and Basic Neurochemistry 41
3 Neuroendocrinology 57
4 Genetics 68
5 Animal Models of Human Behaviour and Mental Disorders 90
PART II PSYCHOPHARMACOLOGY 99
6 General Principles of Psychopharmacology 101
7 Neurotransmitter Receptors and Postsynaptic Signalling Pathways 117
8 Physical Therapies 140
9 Biological Effects of Psychotherapy 146
PART III CLINICAL DISORDERS 151
10 Schizophrenia and Related Disorders 153
11 Depression 184
12 Mania and Bipolar Disorder 202
13 Anxiety Disorders 213
14 Biology of Personality Disorders 229
15 Biology of Substance-Related Disorders 241
16 Eating Disorders and Disorders of Impulse Control 271
17 Mental Disorders of Childhood and Adolescence 282
18 Biology of Sexual and Gender Identity Disorders 300
19 Biology of Sleep Disorders 306
20 Ageing and Dementia 315
21 Neuropsychiatry 333
Afterword: The Future of Biological Psychiatry 355
Glossary: Biological and Neuroanatomical Terms and Methods 358
References 364
Index 381