BOOK
Diagnostic Pathology: Neuropathology E-Book
B.K. Kleinschmidt-DeMasters | Tarik Tihan | Fausto Rodriguez
(2016)
Additional Information
Book Details
Abstract
Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Neuropathology is a visually stunning, easy-to-use reference covering all aspects of neuropathology. Nearly 1,700 outstanding images, including a wide variety of pathology stains and high-quality medical illustrations, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice.
- Thoroughly updated content throughout includes new biomarkers and genetic markers; new diagnostic, therapeutic, and prognostic techniques; new entities and antibodies; new immunohistochemical markers; the new "integrated" diagnosis schema; and much more.
- Features exclusive images not found in the 2016 updated WHO Classification system of CNS neoplasms.
- Presents complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions.
- High-quality, carefully annotated color images (both common and rare) depict classic pathological features as well as variant patterns that are prone to creating diagnostic problems.
- Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover\r | Cover | ||
Diagnostic Pathology: Neuropathology | iii | ||
Copyright Page | iv | ||
Table of Contents | xviii | ||
Dedications | vi | ||
Contributing Authors | ix | ||
Preface | xi | ||
What Is New and WHO Is Changing | xii | ||
Acknowledgments | xv | ||
Sections | xvii | ||
Part I: Neoplastic | 2 | ||
SECTION 1: Brain and Spinal Cord | 2 | ||
Infiltrative Astrocytic Neoplasms | 4 | ||
Chapter 1. Diffuse Astrocytoma | 4 | ||
TERMINOLOGY | 5 | ||
CLINICAL ISSUES | 5 | ||
IMAGING | 5 | ||
MACROSCOPIC | 5 | ||
MICROSCOPIC | 5 | ||
ANCILLARY TESTS | 6 | ||
DIFFERENTIAL DIAGNOSIS | 7 | ||
DIAGNOSTIC CHECKLIST | 7 | ||
SELECTED REFERENCES | 7 | ||
Chapter 2.\rAnaplastic Astrocytoma | 14 | ||
TERMINOLOGY | 15 | ||
CLINICAL ISSUES | 15 | ||
IMAGING | 15 | ||
MACROSCOPIC | 15 | ||
MICROSCOPIC | 15 | ||
ANCILLARY TESTS | 15 | ||
DIFFERENTIAL DIAGNOSIS | 15 | ||
SELECTED REFERENCES | 16 | ||
Chapter 3.\rGlioblastoma | 22 | ||
TERMINOLOGY | 23 | ||
ETIOLOGY/PATHOGENESIS | 23 | ||
CLINICAL ISSUES | 23 | ||
IMAGING | 23 | ||
MACROSCOPIC | 23 | ||
MICROSCOPIC | 24 | ||
ANCILLARY TESTS | 25 | ||
DIFFERENTIAL DIAGNOSIS | 25 | ||
SELECTED REFERENCES | 26 | ||
Chapter 4.\rGliosarcoma | 40 | ||
TERMINOLOGY | 41 | ||
ETIOLOGY/PATHOGENESIS | 41 | ||
CLINICAL ISSUES | 41 | ||
IMAGING | 41 | ||
MACROSCOPIC | 41 | ||
MICROSCOPIC | 41 | ||
ANCILLARY TESTS | 41 | ||
DIFFERENTIAL DIAGNOSIS | 42 | ||
DIAGNOSTIC CHECKLIST | 42 | ||
SELECTED REFERENCES | 42 | ||
Chapter 5.\rGranular Cell Astrocytoma of the Cerebrum | 48 | ||
TERMINOLOGY | 49 | ||
CLINICAL ISSUES | 49 | ||
IMAGING | 49 | ||
MICROSCOPIC | 49 | ||
ANCILLARY TESTS | 49 | ||
DIFFERENTIAL DIAGNOSIS | 49 | ||
DIAGNOSTIC CHECKLIST | 50 | ||
SELECTED REFERENCES | 50 | ||
Oligodendroglial Neoplasms | 54 | ||
Chapter 6.\rOligodendroglioma | 54 | ||
TERMINOLOGY | 55 | ||
CLINICAL ISSUES | 55 | ||
IMAGING | 55 | ||
MACROSCOPIC | 55 | ||
MICROSCOPIC | 55 | ||
ANCILLARY TESTS | 55 | ||
DIFFERENTIAL DIAGNOSIS | 56 | ||
DIAGNOSTIC CHECKLIST | 56 | ||
SELECTED REFERENCES | 56 | ||
Chapter 7.\rAnaplastic Oligodendroglioma | 62 | ||
TERMINOLOGY | 63 | ||
CLINICAL ISSUES | 63 | ||
IMAGING | 63 | ||
MICROSCOPIC | 63 | ||
ANCILLARY TESTS | 63 | ||
SELECTED REFERENCES | 63 | ||
Chapter 8.\rMixed Oligoastrocytoma | 72 | ||
TERMINOLOGY | 73 | ||
CLINICAL ISSUES | 73 | ||
MICROSCOPIC | 73 | ||
ANCILLARY TESTS | 73 | ||
DIFFERENTIAL DIAGNOSIS | 73 | ||
DIAGNOSTIC CHECKLIST | 73 | ||
SELECTED REFERENCES | 73 | ||
Localized Astrocytic Neoplasms | 74 | ||
Chapter 9.\rPilocytic Astrocytoma | 74 | ||
TERMINOLOGY | 75 | ||
ETIOLOGY/PATHOGENESIS | 75 | ||
CLINICAL ISSUES | 75 | ||
IMAGING | 75 | ||
MACROSCOPIC | 75 | ||
MICROSCOPIC | 75 | ||
ANCILLARY TESTS | 76 | ||
DIFFERENTIAL DIAGNOSIS | 76 | ||
DIAGNOSTIC CHECKLIST | 77 | ||
SELECTED REFERENCES | 77 | ||
Chapter 10.\rPilomyxoid Astrocytoma | 86 | ||
TERMINOLOGY | 87 | ||
ETIOLOGY/PATHOGENESIS | 87 | ||
CLINICAL ISSUES | 87 | ||
IMAGING | 87 | ||
MICROSCOPIC | 87 | ||
ANCILLARY TESTS | 87 | ||
DIFFERENTIAL DIAGNOSIS | 88 | ||
DIAGNOSTIC CHECKLIST | 88 | ||
SELECTED REFERENCES | 88 | ||
Chapter 11.\rPleomorphic Xanthoastrocytoma | 92 | ||
TERMINOLOGY | 93 | ||
CLINICAL ISSUES | 93 | ||
IMAGING | 93 | ||
MACROSCOPIC | 93 | ||
MICROSCOPIC | 93 | ||
ANCILLARY TESTS | 93 | ||
DIFFERENTIAL DIAGNOSIS | 94 | ||
DIAGNOSTIC CHECKLIST | 94 | ||
SELECTED REFERENCES | 94 | ||
Chapter 12.\rSubependymal Giant Cell Astrocytoma | 100 | ||
TERMINOLOGY | 101 | ||
ETIOLOGY/PATHOGENESIS | 101 | ||
CLINICAL ISSUES | 101 | ||
IMAGING | 101 | ||
MACROSCOPIC | 101 | ||
MICROSCOPIC | 101 | ||
ANCILLARY TESTS | 101 | ||
DIFFERENTIAL DIAGNOSIS | 102 | ||
DIAGNOSTIC CHECKLIST | 102 | ||
SELECTED REFERENCES | 102 | ||
Tumors of Ependyma and Related Cells | 106 | ||
Chapter 13.\rEpendymoma | 106 | ||
TERMINOLOGY | 107 | ||
ETIOLOGY/PATHOGENESIS | 107 | ||
CLINICAL ISSUES | 107 | ||
IMAGING | 107 | ||
MACROSCOPIC | 107 | ||
MICROSCOPIC | 107 | ||
ANCILLARY TESTS | 108 | ||
DIFFERENTIAL DIAGNOSIS | 109 | ||
DIAGNOSTIC CHECKLIST | 109 | ||
SELECTED REFERENCES | 109 | ||
Chapter 14.\rAnaplastic Ependymoma | 122 | ||
TERMINOLOGY | 123 | ||
CLINICAL ISSUES | 123 | ||
IMAGING | 123 | ||
MICROSCOPIC | 123 | ||
ANCILLARY TESTS | 123 | ||
DIFFERENTIAL DIAGNOSIS | 123 | ||
SELECTED REFERENCES | 123 | ||
Chapter 15.\rMyxopapillary Ependymoma | 128 | ||
TERMINOLOGY | 129 | ||
CLINICAL ISSUES | 129 | ||
IMAGING | 129 | ||
MACROSCOPIC | 129 | ||
MICROSCOPIC | 129 | ||
ANCILLARY TESTS | 129 | ||
DIFFERENTIAL DIAGNOSIS | 129 | ||
DIAGNOSTIC CHECKLIST | 129 | ||
SELECTED REFERENCES | 129 | ||
Chapter 16.\rSubependymoma | 134 | ||
TERMINOLOGY | 135 | ||
CLINICAL ISSUES | 135 | ||
IMAGING | 135 | ||
MACROSCOPIC | 135 | ||
MICROSCOPIC | 135 | ||
ANCILLARY TESTS | 135 | ||
DIFFERENTIAL DIAGNOSIS | 135 | ||
SELECTED REFERENCES | 135 | ||
Chapter 17.\rAstroblastoma | 138 | ||
TERMINOLOGY | 139 | ||
CLINICAL ISSUES | 139 | ||
IMAGING | 139 | ||
MACROSCOPIC | 139 | ||
MICROSCOPIC | 139 | ||
ANCILLARY TESTS | 139 | ||
DIFFERENTIAL DIAGNOSIS | 139 | ||
DIAGNOSTIC CHECKLIST | 140 | ||
SELECTED REFERENCES | 140 | ||
Chapter 18.\rAngiocentric Glioma | 144 | ||
TERMINOLOGY | 145 | ||
CLINICAL ISSUES | 145 | ||
IMAGING | 145 | ||
MACROSCOPIC | 145 | ||
MICROSCOPIC | 145 | ||
ANCILLARY TESTS | 145 | ||
DIFFERENTIAL DIAGNOSIS | 145 | ||
DIAGNOSTIC CHECKLIST | 145 | ||
SELECTED REFERENCES | 145 | ||
Chapter 19.\rChordoid Glioma of 3rd Ventricle | 150 | ||
TERMINOLOGY | 151 | ||
CLINICAL ISSUES | 151 | ||
IMAGING | 151 | ||
MACROSCOPIC | 151 | ||
MICROSCOPIC | 151 | ||
ANCILLARY TESTS | 151 | ||
DIFFERENTIAL DIAGNOSIS | 151 | ||
SELECTED REFERENCES | 151 | ||
Choroid Plexus Neoplasms | 154 | ||
Chapter 20.\rChoroid Plexus Papilloma and Atypical Papilloma | 154 | ||
TERMINOLOGY | 155 | ||
ETIOLOGY/PATHOGENESIS | 155 | ||
CLINICAL ISSUES | 155 | ||
IMAGING | 155 | ||
MACROSCOPIC | 155 | ||
MICROSCOPIC | 155 | ||
ANCILLARY TESTS | 155 | ||
DIFFERENTIAL DIAGNOSIS | 155 | ||
SELECTED REFERENCES | 155 | ||
Chapter 21.\rChoroid Plexus Carcinoma | 160 | ||
TERMINOLOGY | 161 | ||
ETIOLOGY/PATHOGENESIS | 161 | ||
CLINICAL ISSUES | 161 | ||
IMAGING | 161 | ||
MACROSCOPIC | 161 | ||
MICROSCOPIC | 161 | ||
ANCILLARY TESTS | 161 | ||
DIFFERENTIAL DIAGNOSIS | 161 | ||
DIAGNOSTIC CHECKLIST | 162 | ||
SELECTED REFERENCES | 162 | ||
Neuronal and Glioneuronal Neoplasms | 168 | ||
Chapter 22.\rGanglion Cell Tumors | 168 | ||
TERMINOLOGY | 169 | ||
ETIOLOGY/PATHOGENESIS | 169 | ||
CLINICAL ISSUES | 169 | ||
IMAGING | 169 | ||
MACROSCOPIC | 169 | ||
MICROSCOPIC | 169 | ||
ANCILLARY TESTS | 170 | ||
DIFFERENTIAL DIAGNOSIS | 171 | ||
DIAGNOSTIC CHECKLIST | 172 | ||
SELECTED REFERENCES | 172 | ||
Chapter 23.\rDesmoplastic Infantile Ganglioglioma | 178 | ||
TERMINOLOGY | 179 | ||
CLINICAL ISSUES | 179 | ||
IMAGING | 179 | ||
MACROSCOPIC | 179 | ||
MICROSCOPIC | 179 | ||
ANCILLARY TESTS | 179 | ||
DIFFERENTIAL DIAGNOSIS | 179 | ||
SELECTED REFERENCES | 179 | ||
Chapter 24.\rDysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) | 184 | ||
TERMINOLOGY | 185 | ||
ETIOLOGY/PATHOGENESIS | 185 | ||
CLINICAL ISSUES | 185 | ||
IMAGING | 185 | ||
MACROSCOPIC | 185 | ||
MICROSCOPIC | 185 | ||
ANCILLARY TESTS | 185 | ||
DIFFERENTIAL DIAGNOSIS | 185 | ||
DIAGNOSTIC CHECKLIST | 185 | ||
SELECTED REFERENCES | 185 | ||
Chapter 25.\rCentral Neurocytoma | 188 | ||
TERMINOLOGY | 189 | ||
CLINICAL ISSUES | 189 | ||
IMAGING | 189 | ||
MICROSCOPIC | 189 | ||
ANCILLARY TESTS | 189 | ||
DIFFERENTIAL DIAGNOSIS | 189 | ||
SELECTED REFERENCES | 189 | ||
Chapter 26.\rExtraventricular Neurocytoma | 194 | ||
TERMINOLOGY | 195 | ||
CLINICAL ISSUES | 195 | ||
IMAGING | 195 | ||
MACROSCOPIC | 195 | ||
MICROSCOPIC | 195 | ||
ANCILLARY TESTS | 195 | ||
DIFFERENTIAL DIAGNOSIS | 195 | ||
SELECTED REFERENCES | 195 | ||
Chapter 27.\rCerebellar Liponeurocytoma | 200 | ||
TERMINOLOGY | 201 | ||
CLINICAL ISSUES | 201 | ||
IMAGING | 201 | ||
MICROSCOPIC | 201 | ||
ANCILLARY TESTS | 201 | ||
DIFFERENTIAL DIAGNOSIS | 201 | ||
DIAGNOSTIC CHECKLIST | 201 | ||
SELECTED REFERENCES | 201 | ||
Chapter 28.\rDysembryoplastic Neuroepithelial Tumor | 202 | ||
TERMINOLOGY | 203 | ||
CLINICAL ISSUES | 203 | ||
IMAGING | 203 | ||
MACROSCOPIC | 203 | ||
MICROSCOPIC | 203 | ||
ANCILLARY TESTS | 203 | ||
DIFFERENTIAL DIAGNOSIS | 204 | ||
DIAGNOSTIC CHECKLIST | 204 | ||
SELECTED REFERENCES | 204 | ||
Chapter 29.\rRosette-Forming Glioneuronal Tumor of 4th Ventricle | 210 | ||
TERMINOLOGY | 211 | ||
ETIOLOGY/PATHOGENESIS | 211 | ||
CLINICAL ISSUES | 211 | ||
IMAGING | 211 | ||
MICROSCOPIC | 211 | ||
ANCILLARY TESTS | 211 | ||
DIFFERENTIAL DIAGNOSIS | 211 | ||
DIAGNOSTIC CHECKLIST | 211 | ||
SELECTED REFERENCES | 211 | ||
Chapter 30.\rPapillary Glioneuronal Tumor | 214 | ||
TERMINOLOGY | 215 | ||
CLINICAL ISSUES | 215 | ||
IMAGING | 215 | ||
MACROSCOPIC | 215 | ||
MICROSCOPIC | 215 | ||
ANCILLARY TESTS | 215 | ||
DIFFERENTIAL DIAGNOSIS | 215 | ||
DIAGNOSTIC CHECKLIST | 215 | ||
SELECTED REFERENCES | 215 | ||
Chapter 31.\rParaganglioma of Filum Terminale | 218 | ||
TERMINOLOGY | 219 | ||
CLINICAL ISSUES | 219 | ||
IMAGING | 219 | ||
MACROSCOPIC | 219 | ||
MICROSCOPIC | 219 | ||
ANCILLARY TESTS | 219 | ||
DIFFERENTIAL DIAGNOSIS | 219 | ||
DIAGNOSTIC CHECKLIST | 219 | ||
SELECTED REFERENCES | 219 | ||
Chapter 32.\rMalignant Glioneuronal Tumors | 222 | ||
TERMINOLOGY | 223 | ||
CLINICAL ISSUES | 223 | ||
MICROSCOPIC | 223 | ||
ANCILLARY TESTS | 223 | ||
DIFFERENTIAL DIAGNOSIS | 223 | ||
DIAGNOSTIC CHECKLIST | 223 | ||
SELECTED REFERENCES | 223 | ||
Chapter 33.\rDiffuse Leptomeningeal Glioneuronal Tumor | 226 | ||
TERMINOLOGY | 227 | ||
CLINICAL ISSUES | 227 | ||
IMAGING | 227 | ||
MICROSCOPIC | 227 | ||
ANCILLARY TESTS | 227 | ||
DIFFERENTIAL DIAGNOSIS | 227 | ||
DIAGNOSTIC CHECKLIST | 227 | ||
SELECTED REFERENCES | 227 | ||
Pineal Parenchymal Neoplasms | 228 | ||
Chapter 34.\rPineal Parenchymal Neoplasms | 228 | ||
TERMINOLOGY | 229 | ||
ETIOLOGY/PATHOGENESIS | 229 | ||
CLINICAL ISSUES | 229 | ||
IMAGING | 229 | ||
MICROSCOPIC | 229 | ||
ANCILLARY TESTS | 229 | ||
DIFFERENTIAL DIAGNOSIS | 229 | ||
DIAGNOSTIC CHECKLIST | 230 | ||
SELECTED REFERENCES | 230 | ||
Chapter 35.\rPapillary Tumor of the Pineal Region | 236 | ||
TERMINOLOGY | 237 | ||
ETIOLOGY/PATHOGENESIS | 237 | ||
CLINICAL ISSUES | 237 | ||
IMAGING | 237 | ||
MICROSCOPIC | 237 | ||
ANCILLARY TESTS | 237 | ||
DIFFERENTIAL DIAGNOSIS | 237 | ||
SELECTED REFERENCES | 237 | ||
Chapter 36.\rPineal Anlage Tumor | 240 | ||
TERMINOLOGY | 241 | ||
CLINICAL ISSUES | 241 | ||
IMAGING | 241 | ||
MACROSCOPIC | 241 | ||
MICROSCOPIC | 241 | ||
ANCILLARY TESTS | 241 | ||
DIFFERENTIAL DIAGNOSIS | 241 | ||
SELECTED REFERENCES | 241 | ||
Embryonal Neoplasms | 244 | ||
Chapter 37.\rMedulloblastoma | 244 | ||
TERMINOLOGY | 245 | ||
ETIOLOGY/PATHOGENESIS | 245 | ||
CLINICAL ISSUES | 245 | ||
IMAGING | 245 | ||
MACROSCOPIC | 245 | ||
MICROSCOPIC | 245 | ||
ANCILLARY TESTS | 246 | ||
DIFFERENTIAL DIAGNOSIS | 247 | ||
DIAGNOSTIC CHECKLIST | 247 | ||
SELECTED REFERENCES | 247 | ||
Chapter 38.\rCNS Embryonal Neoplasms | 258 | ||
TERMINOLOGY | 259 | ||
CLINICAL ISSUES | 259 | ||
IMAGING | 259 | ||
MICROSCOPIC | 259 | ||
ANCILLARY TESTS | 260 | ||
DIFFERENTIAL DIAGNOSIS | 260 | ||
DIAGNOSTIC CHECKLIST | 260 | ||
SELECTED REFERENCES | 260 | ||
Chapter 39.\rEmbryonal Tumor With Multilayered Rosettes, C19MC Altered | 264 | ||
TERMINOLOGY | 265 | ||
CLINICAL ISSUES | 265 | ||
IMAGING | 265 | ||
MACROSCOPIC | 265 | ||
MICROSCOPIC | 265 | ||
ANCILLARY TESTS | 265 | ||
DIFFERENTIAL DIAGNOSIS | 265 | ||
DIAGNOSTIC CHECKLIST | 265 | ||
SELECTED REFERENCES | 265 | ||
Chapter 40.\rEwing Sarcoma | 268 | ||
TERMINOLOGY | 269 | ||
ETIOLOGY/PATHOGENESIS | 269 | ||
CLINICAL ISSUES | 269 | ||
IMAGING | 269 | ||
MICROSCOPIC | 269 | ||
ANCILLARY TESTS | 269 | ||
DIFFERENTIAL DIAGNOSIS | 269 | ||
DIAGNOSTIC CHECKLIST | 269 | ||
SELECTED REFERENCES | 269 | ||
Chapter 41.\rAtypical Teratoid/Rhabdoid Tumor | 272 | ||
TERMINOLOGY | 273 | ||
ETIOLOGY/PATHOGENESIS | 273 | ||
CLINICAL ISSUES | 273 | ||
IMAGING | 273 | ||
MACROSCOPIC | 273 | ||
MICROSCOPIC | 273 | ||
ANCILLARY TESTS | 273 | ||
DIFFERENTIAL DIAGNOSIS | 274 | ||
DIAGNOSTIC CHECKLIST | 274 | ||
SELECTED REFERENCES | 275 | ||
Germ Cell Neoplasms | 282 | ||
Chapter 42.\rGerminoma | 282 | ||
TERMINOLOGY | 283 | ||
CLINICAL ISSUES | 283 | ||
IMAGING | 283 | ||
MACROSCOPIC | 283 | ||
MICROSCOPIC | 283 | ||
ANCILLARY TESTS | 283 | ||
DIFFERENTIAL DIAGNOSIS | 284 | ||
DIAGNOSTIC CHECKLIST | 284 | ||
SELECTED REFERENCES | 284 | ||
Chapter 43.\rTeratomas | 288 | ||
TERMINOLOGY | 289 | ||
CLINICAL ISSUES | 289 | ||
IMAGING | 289 | ||
MICROSCOPIC | 289 | ||
ANCILLARY TESTS | 289 | ||
DIFFERENTIAL DIAGNOSIS | 289 | ||
SELECTED REFERENCES | 289 | ||
Chapter 44.\rOther Germ Cell Tumors | 292 | ||
TERMINOLOGY | 293 | ||
CLINICAL ISSUES | 293 | ||
IMAGING | 293 | ||
MICROSCOPIC | 293 | ||
ANCILLARY TESTS | 294 | ||
DIFFERENTIAL DIAGNOSIS | 294 | ||
DIAGNOSTIC CHECKLIST | 294 | ||
SELECTED REFERENCES | 294 | ||
Hemangioblastoma | 298 | ||
Chapter 45.\rHemangioblastoma | 298 | ||
TERMINOLOGY | 299 | ||
ETIOLOGY/PATHOGENESIS | 299 | ||
CLINICAL ISSUES | 299 | ||
IMAGING | 299 | ||
MACROSCOPIC | 299 | ||
MICROSCOPIC | 299 | ||
ANCILLARY TESTS | 299 | ||
DIFFERENTIAL DIAGNOSIS | 300 | ||
DIAGNOSTIC CHECKLIST | 300 | ||
SELECTED REFERENCES | 300 | ||
Lymphomas and Hematopoietic Neoplasms | 306 | ||
Chapter 46.\rPrimary Central Nervous System Lymphoma | 306 | ||
TERMINOLOGY | 307 | ||
ETIOLOGY/PATHOGENESIS | 307 | ||
CLINICAL ISSUES | 307 | ||
IMAGING | 307 | ||
MACROSCOPIC | 307 | ||
MICROSCOPIC | 307 | ||
ANCILLARY TESTS | 308 | ||
DIFFERENTIAL DIAGNOSIS | 308 | ||
DIAGNOSTIC CHECKLIST | 309 | ||
SELECTED REFERENCES | 309 | ||
Chapter 47.\rIntravascular Lymphomatosis | 316 | ||
TERMINOLOGY | 317 | ||
CLINICAL ISSUES | 317 | ||
IMAGING | 317 | ||
MACROSCOPIC | 317 | ||
MICROSCOPIC | 317 | ||
ANCILLARY TESTS | 317 | ||
DIFFERENTIAL DIAGNOSIS | 317 | ||
DIAGNOSTIC CHECKLIST | 317 | ||
SELECTED REFERENCES | 317 | ||
Chapter 48.\rLymphomatosis Cerebri | 320 | ||
TERMINOLOGY | 321 | ||
CLINICAL ISSUES | 321 | ||
IMAGING | 321 | ||
MICROSCOPIC | 321 | ||
ANCILLARY TESTS | 321 | ||
DIFFERENTIAL DIAGNOSIS | 321 | ||
DIAGNOSTIC CHECKLIST | 321 | ||
SELECTED REFERENCES | 321 | ||
Chapter 49.\rLymphomatoid Granulomatosis | 322 | ||
TERMINOLOGY | 323 | ||
ETIOLOGY/PATHOGENESIS | 323 | ||
CLINICAL ISSUES | 323 | ||
MICROSCOPIC | 323 | ||
ANCILLARY TESTS | 323 | ||
DIFFERENTIAL DIAGNOSIS | 323 | ||
SELECTED REFERENCES | 323 | ||
Chapter 50.\rPrimary Amyloidoma | 324 | ||
TERMINOLOGY | 325 | ||
ETIOLOGY/PATHOGENESIS | 325 | ||
CLINICAL ISSUES | 325 | ||
IMAGING | 325 | ||
MACROSCOPIC | 325 | ||
MICROSCOPIC | 325 | ||
ANCILLARY TESTS | 325 | ||
DIFFERENTIAL DIAGNOSIS | 325 | ||
DIAGNOSTIC CHECKLIST | 325 | ||
SELECTED REFERENCES | 325 | ||
Chapter 51.\rErdheim-Chester Disease | 326 | ||
TERMINOLOGY | 327 | ||
ETIOLOGY/PATHOGENESIS | 327 | ||
CLINICAL ISSUES | 327 | ||
IMAGING | 327 | ||
MACROSCOPIC | 327 | ||
MICROSCOPIC | 327 | ||
ANCILLARY TESTS | 328 | ||
DIFFERENTIAL DIAGNOSIS | 328 | ||
DIAGNOSTIC CHECKLIST | 328 | ||
SELECTED REFERENCES | 328 | ||
Chapter 52.\rLangerhans Cell Histiocytosis | 332 | ||
TERMINOLOGY | 333 | ||
CLINICAL ISSUES | 333 | ||
IMAGING | 333 | ||
MACROSCOPIC | 333 | ||
MICROSCOPIC | 333 | ||
ANCILLARY TESTS | 333 | ||
DIFFERENTIAL DIAGNOSIS | 333 | ||
DIAGNOSTIC CHECKLIST | 334 | ||
SELECTED REFERENCES | 334 | ||
Metastatic Neoplasms | 338 | ||
Chapter 53.\rMetastatic Neoplasms, Intraparenchymal, Brain and Spinal Cord | 338 | ||
TERMINOLOGY | 339 | ||
CLINICAL ISSUES | 339 | ||
IMAGING | 339 | ||
MACROSCOPIC | 339 | ||
MICROSCOPIC | 339 | ||
ANCILLARY TESTS | 339 | ||
DIFFERENTIAL DIAGNOSIS | 340 | ||
DIAGNOSTIC CHECKLIST | 341 | ||
SELECTED REFERENCES | 341 | ||
SECTION 2: Sellar Region | 351 | ||
Adenohypophyseal Neoplasia and Hyperplasia | 352 | ||
Chapter 54.\rPituitary Adenoma | 352 | ||
TERMINOLOGY | 353 | ||
ETIOLOGY/PATHOGENESIS | 353 | ||
CLINICAL ISSUES | 353 | ||
IMAGING | 354 | ||
MICROSCOPIC | 354 | ||
ANCILLARY TESTS | 354 | ||
DIFFERENTIAL DIAGNOSIS | 354 | ||
SELECTED REFERENCES | 354 | ||
Chapter 55.\rProlactinoma | 362 | ||
TERMINOLOGY | 363 | ||
ETIOLOGY/PATHOGENESIS | 363 | ||
CLINICAL ISSUES | 363 | ||
IMAGING | 364 | ||
MACROSCOPIC | 364 | ||
MICROSCOPIC | 364 | ||
ANCILLARY TESTS | 364 | ||
DIFFERENTIAL DIAGNOSIS | 364 | ||
DIAGNOSTIC CHECKLIST | 364 | ||
SELECTED REFERENCES | 364 | ||
Chapter 56.\rSomatotroph Adenoma | 366 | ||
TERMINOLOGY | 367 | ||
ETIOLOGY/PATHOGENESIS | 367 | ||
CLINICAL ISSUES | 367 | ||
IMAGING | 368 | ||
MACROSCOPIC | 368 | ||
MICROSCOPIC | 368 | ||
ANCILLARY TESTS | 369 | ||
DIFFERENTIAL DIAGNOSIS | 370 | ||
DIAGNOSTIC CHECKLIST | 370 | ||
SELECTED REFERENCES | 370 | ||
Chapter 57.\rCorticotroph Adenoma | 376 | ||
TERMINOLOGY | 377 | ||
ETIOLOGY/PATHOGENESIS | 377 | ||
CLINICAL ISSUES | 377 | ||
IMAGING | 377 | ||
MACROSCOPIC | 377 | ||
MICROSCOPIC | 377 | ||
ANCILLARY TESTS | 378 | ||
DIFFERENTIAL DIAGNOSIS | 378 | ||
DIAGNOSTIC CHECKLIST | 378 | ||
SELECTED REFERENCES | 378 | ||
Chapter 58.\rGonadotroph Adenoma | 382 | ||
TERMINOLOGY | 383 | ||
CLINICAL ISSUES | 383 | ||
IMAGING | 383 | ||
MACROSCOPIC | 383 | ||
MICROSCOPIC | 383 | ||
ANCILLARY TESTS | 383 | ||
DIFFERENTIAL DIAGNOSIS | 384 | ||
SELECTED REFERENCES | 384 | ||
Chapter 59.\rThyrotroph Adenoma | 388 | ||
TERMINOLOGY | 389 | ||
ETIOLOGY/PATHOGENESIS | 389 | ||
CLINICAL ISSUES | 389 | ||
IMAGING | 389 | ||
MACROSCOPIC | 389 | ||
MICROSCOPIC | 389 | ||
ANCILLARY TESTS | 389 | ||
SELECTED REFERENCES | 389 | ||
Chapter 60.\rPlurihormonal Adenoma | 392 | ||
TERMINOLOGY | 393 | ||
ETIOLOGY/PATHOGENESIS | 393 | ||
CLINICAL ISSUES | 393 | ||
IMAGING | 393 | ||
MACROSCOPIC | 393 | ||
MICROSCOPIC | 393 | ||
ANCILLARY TESTS | 393 | ||
DIFFERENTIAL DIAGNOSIS | 393 | ||
SELECTED REFERENCES | 393 | ||
Chapter 61.\rNull Cell Adenoma | 396 | ||
TERMINOLOGY | 397 | ||
ETIOLOGY/PATHOGENESIS | 397 | ||
CLINICAL ISSUES | 397 | ||
IMAGING | 397 | ||
MACROSCOPIC | 397 | ||
MICROSCOPIC | 397 | ||
ANCILLARY TESTS | 397 | ||
SELECTED REFERENCES | 397 | ||
Chapter 62.\rPituitary Hyperplasia | 400 | ||
TERMINOLOGY | 401 | ||
ETIOLOGY/PATHOGENESIS | 401 | ||
CLINICAL ISSUES | 401 | ||
IMAGING | 401 | ||
MICROSCOPIC | 401 | ||
ANCILLARY TESTS | 401 | ||
DIFFERENTIAL DIAGNOSIS | 401 | ||
SELECTED REFERENCES | 401 | ||
Chapter 63.\rPituitary Carcinoma | 404 | ||
TERMINOLOGY | 405 | ||
ETIOLOGY/PATHOGENESIS | 405 | ||
CLINICAL ISSUES | 405 | ||
IMAGING | 405 | ||
MACROSCOPIC | 405 | ||
MICROSCOPIC | 406 | ||
ANCILLARY TESTS | 406 | ||
DIFFERENTIAL DIAGNOSIS | 406 | ||
DIAGNOSTIC CHECKLIST | 406 | ||
GRADING | 406 | ||
SELECTED REFERENCES | 406 | ||
Neurohypophyseal and Hypothalamic Neoplasms | 408 | ||
Chapter 64.\rHypothalamic Hamartoma | 408 | ||
TERMINOLOGY | 409 | ||
ETIOLOGY/PATHOGENESIS | 409 | ||
CLINICAL ISSUES | 409 | ||
IMAGING | 409 | ||
MACROSCOPIC | 409 | ||
MICROSCOPIC | 409 | ||
ANCILLARY TESTS | 409 | ||
DIFFERENTIAL DIAGNOSIS | 409 | ||
DIAGNOSTIC CHECKLIST | 409 | ||
SELECTED REFERENCES | 409 | ||
Chapter 65.\rGranular Cell Tumor of Infundibulum | 410 | ||
TERMINOLOGY | 411 | ||
CLINICAL ISSUES | 411 | ||
IMAGING | 411 | ||
MACROSCOPIC | 411 | ||
MICROSCOPIC | 411 | ||
ANCILLARY TESTS | 411 | ||
DIFFERENTIAL DIAGNOSIS | 411 | ||
SELECTED REFERENCES | 411 | ||
Chapter 66.\rPituicytoma | 414 | ||
TERMINOLOGY | 415 | ||
CLINICAL ISSUES | 415 | ||
IMAGING | 415 | ||
MACROSCOPIC | 415 | ||
MICROSCOPIC | 415 | ||
ANCILLARY TESTS | 415 | ||
DIFFERENTIAL DIAGNOSIS | 415 | ||
SELECTED REFERENCES | 415 | ||
Craniopharyngiomas | 418 | ||
Chapter 67.\rAdamantinomatous Craniopharyngioma | 418 | ||
TERMINOLOGY | 419 | ||
ETIOLOGY/PATHOGENESIS | 419 | ||
CLINICAL ISSUES | 419 | ||
IMAGING | 419 | ||
MACROSCOPIC | 419 | ||
MICROSCOPIC | 419 | ||
ANCILLARY TESTS | 420 | ||
DIFFERENTIAL DIAGNOSIS | 420 | ||
DIAGNOSTIC CHECKLIST | 420 | ||
SELECTED REFERENCES | 420 | ||
Chapter 68.\rPapillary Craniopharyngioma | 426 | ||
TERMINOLOGY | 427 | ||
ETIOLOGY/PATHOGENESIS | 427 | ||
CLINICAL ISSUES | 427 | ||
IMAGING | 427 | ||
MACROSCOPIC | 427 | ||
MICROSCOPIC | 427 | ||
ANCILLARY TESTS | 427 | ||
DIFFERENTIAL DIAGNOSIS | 427 | ||
DIAGNOSTIC CHECKLIST | 428 | ||
SELECTED REFERENCES | 428 | ||
Miscellaneous Neoplasms | 434 | ||
Chapter 69.\rSpindle Cell Oncocytoma | 434 | ||
TERMINOLOGY | 435 | ||
CLINICAL ISSUES | 435 | ||
IMAGING | 435 | ||
MACROSCOPIC | 435 | ||
MICROSCOPIC | 435 | ||
ANCILLARY TESTS | 435 | ||
DIFFERENTIAL DIAGNOSIS | 435 | ||
SELECTED REFERENCES | 435 | ||
Chapter 70.\rPituitary Blastoma | 438 | ||
TERMINOLOGY | 439 | ||
ETIOLOGY/PATHOGENESIS | 439 | ||
CLINICAL ISSUES | 439 | ||
IMAGING | 439 | ||
MICROSCOPIC | 439 | ||
ANCILLARY TESTS | 439 | ||
DIFFERENTIAL DIAGNOSIS | 439 | ||
SELECTED REFERENCES | 439 | ||
Chapter 71.\rSecondary Neoplasms of the Pituitary and Sellar Region | 442 | ||
TERMINOLOGY | 443 | ||
ETIOLOGY/PATHOGENESIS | 443 | ||
CLINICAL ISSUES | 443 | ||
IMAGING | 443 | ||
MACROSCOPIC | 443 | ||
MICROSCOPIC | 443 | ||
ANCILLARY TESTS | 444 | ||
DIFFERENTIAL DIAGNOSIS | 444 | ||
DIAGNOSTIC CHECKLIST | 444 | ||
SELECTED REFERENCES | 444 | ||
SECTION 3: Meninges | 449 | ||
Chapter 72.\rMeningioma | 450 | ||
TERMINOLOGY | 451 | ||
ETIOLOGY/PATHOGENESIS | 451 | ||
CLINICAL ISSUES | 451 | ||
IMAGING | 451 | ||
MACROSCOPIC | 451 | ||
MICROSCOPIC | 452 | ||
ANCILLARY TESTS | 453 | ||
DIFFERENTIAL DIAGNOSIS | 453 | ||
DIAGNOSTIC CHECKLIST | 454 | ||
GRADING | 454 | ||
SELECTED REFERENCES | 454 | ||
Chapter 73.\rSolitary Fibrous Tumor | 468 | ||
TERMINOLOGY | 469 | ||
CLINICAL ISSUES | 469 | ||
IMAGING | 469 | ||
MACROSCOPIC | 469 | ||
MICROSCOPIC | 469 | ||
ANCILLARY TESTS | 470 | ||
DIFFERENTIAL DIAGNOSIS | 470 | ||
DIAGNOSTIC CHECKLIST | 470 | ||
GRADING | 470 | ||
SELECTED REFERENCES | 470 | ||
Chapter 74.\rPrimary Melanocytic Neoplasms | 476 | ||
TERMINOLOGY | 477 | ||
ETIOLOGY/PATHOGENESIS | 477 | ||
CLINICAL ISSUES | 477 | ||
IMAGING | 477 | ||
MACROSCOPIC | 477 | ||
MICROSCOPIC | 477 | ||
ANCILLARY TESTS | 478 | ||
DIFFERENTIAL DIAGNOSIS | 478 | ||
DIAGNOSTIC CHECKLIST | 478 | ||
GRADING | 478 | ||
SELECTED REFERENCES | 478 | ||
Chapter 75.\rOsteocartilaginous Neoplasms | 482 | ||
TERMINOLOGY | 483 | ||
ETIOLOGY/PATHOGENESIS | 483 | ||
CLINICAL ISSUES | 483 | ||
IMAGING | 483 | ||
MACROSCOPIC | 484 | ||
MICROSCOPIC | 484 | ||
ANCILLARY TESTS | 484 | ||
DIFFERENTIAL DIAGNOSIS | 485 | ||
DIAGNOSTIC CHECKLIST | 485 | ||
SELECTED REFERENCES | 485 | ||
Chapter 76.\rFibrosarcoma | 490 | ||
TERMINOLOGY | 491 | ||
ETIOLOGY/PATHOGENESIS | 491 | ||
CLINICAL ISSUES | 491 | ||
MACROSCOPIC | 491 | ||
MICROSCOPIC | 491 | ||
ANCILLARY TESTS | 491 | ||
DIFFERENTIAL DIAGNOSIS | 491 | ||
SELECTED REFERENCES | 491 | ||
Chapter 77.\rSmooth Muscle Neoplasms | 492 | ||
TERMINOLOGY | 493 | ||
ETIOLOGY/PATHOGENESIS | 493 | ||
CLINICAL ISSUES | 493 | ||
IMAGING | 493 | ||
MACROSCOPIC | 493 | ||
MICROSCOPIC | 493 | ||
ANCILLARY TESTS | 493 | ||
DIFFERENTIAL DIAGNOSIS | 493 | ||
DIAGNOSTIC CHECKLIST | 493 | ||
SELECTED REFERENCES | 493 | ||
Chapter 78.\rAdipocytic Neoplasms | 494 | ||
TERMINOLOGY | 495 | ||
ETIOLOGY/PATHOGENESIS | 495 | ||
CLINICAL ISSUES | 495 | ||
IMAGING | 495 | ||
MACROSCOPIC | 495 | ||
MICROSCOPIC | 495 | ||
ANCILLARY TESTS | 496 | ||
DIFFERENTIAL DIAGNOSIS | 496 | ||
DIAGNOSTIC CHECKLIST | 496 | ||
GRADING | 496 | ||
SELECTED REFERENCES | 496 | ||
Chapter 79.\rMeningeal Glioma and Gliomatosis | 498 | ||
TERMINOLOGY | 499 | ||
ETIOLOGY/PATHOGENESIS | 499 | ||
CLINICAL ISSUES | 499 | ||
IMAGING | 499 | ||
MACROSCOPIC | 499 | ||
MICROSCOPIC | 499 | ||
ANCILLARY TESTS | 499 | ||
DIFFERENTIAL DIAGNOSIS | 499 | ||
DIAGNOSTIC CHECKLIST | 499 | ||
SELECTED REFERENCES | 499 | ||
Chapter 80.\rMetastatic Neoplasms, Intracranial and Intraspinal Meninges | 500 | ||
TERMINOLOGY | 501 | ||
ETIOLOGY/PATHOGENESIS | 501 | ||
CLINICAL ISSUES | 501 | ||
IMAGING | 501 | ||
MACROSCOPIC | 501 | ||
MICROSCOPIC | 501 | ||
ANCILLARY TESTS | 502 | ||
DIFFERENTIAL DIAGNOSIS | 502 | ||
DIAGNOSTIC CHECKLIST | 502 | ||
SELECTED REFERENCES | 502 | ||
SECTION 4: Cranial, Spinal, and Peripheral Nerves | 507 | ||
Schwannoma Variants | 508 | ||
Chapter 81.\rConventional Schwannoma | 508 | ||
TERMINOLOGY | 509 | ||
ETIOLOGY/PATHOGENESIS | 509 | ||
CLINICAL ISSUES | 509 | ||
IMAGING | 509 | ||
MACROSCOPIC | 509 | ||
MICROSCOPIC | 509 | ||
ANCILLARY TESTS | 510 | ||
DIFFERENTIAL DIAGNOSIS | 510 | ||
SELECTED REFERENCES | 510 | ||
Chapter 82.\rCellular Schwannoma | 518 | ||
TERMINOLOGY | 519 | ||
ETIOLOGY/PATHOGENESIS | 519 | ||
CLINICAL ISSUES | 519 | ||
MACROSCOPIC | 519 | ||
MICROSCOPIC | 519 | ||
ANCILLARY TESTS | 519 | ||
DIFFERENTIAL DIAGNOSIS | 519 | ||
SELECTED REFERENCES | 519 | ||
Chapter 83.\rMelanotic Schwannoma | 522 | ||
TERMINOLOGY | 523 | ||
CLINICAL ISSUES | 523 | ||
IMAGING | 523 | ||
MACROSCOPIC | 523 | ||
MICROSCOPIC | 523 | ||
ANCILLARY TESTS | 524 | ||
DIFFERENTIAL DIAGNOSIS | 524 | ||
DIAGNOSTIC CHECKLIST | 524 | ||
SELECTED REFERENCES | 524 | ||
Chapter 84.\rPlexiform Schwannoma | 528 | ||
TERMINOLOGY | 529 | ||
CLINICAL ISSUES | 529 | ||
MACROSCOPIC | 529 | ||
MICROSCOPIC | 529 | ||
ANCILLARY TESTS | 529 | ||
DIFFERENTIAL DIAGNOSIS | 529 | ||
SELECTED REFERENCES | 529 | ||
Neurofibroma | 532 | ||
Chapter 85.\rPlexiform Neurofibroma | 532 | ||
TERMINOLOGY | 533 | ||
CLINICAL ISSUES | 533 | ||
IMAGING | 533 | ||
MACROSCOPIC | 533 | ||
MICROSCOPIC | 533 | ||
ANCILLARY TESTS | 533 | ||
DIFFERENTIAL DIAGNOSIS | 533 | ||
SELECTED REFERENCES | 533 | ||
Chapter 86.\rLocalized Intraneural Neurofibroma | 536 | ||
TERMINOLOGY | 537 | ||
CLINICAL ISSUES | 537 | ||
IMAGING | 537 | ||
MACROSCOPIC | 537 | ||
MICROSCOPIC | 537 | ||
ANCILLARY TESTS | 537 | ||
DIFFERENTIAL DIAGNOSIS | 537 | ||
SELECTED REFERENCES | 537 | ||
Chapter 87.\rExtraneural Neurofibroma Variants | 540 | ||
TERMINOLOGY | 540 | ||
EPIDEMIOLOGY | 540 | ||
ETIOLOGY/PATHOGENESIS | 540 | ||
CLINICAL IMPLICATIONS | 540 | ||
MACROSCOPIC | 540 | ||
MICROSCOPIC | 540 | ||
VARIANTS | 541 | ||
ANCILLARY TESTS | 541 | ||
DIFFERENTIAL DIAGNOSIS | 541 | ||
SELECTED REFERENCES | 541 | ||
Primary Malignant Neoplasms of Nerve | 546 | ||
Chapter 88.\rMalignant Peripheral Nerve Sheath Tumor | 546 | ||
TERMINOLOGY | 547 | ||
ETIOLOGY/PATHOGENESIS | 547 | ||
CLINICAL ISSUES | 547 | ||
IMAGING | 547 | ||
MACROSCOPIC | 548 | ||
MICROSCOPIC | 548 | ||
ANCILLARY TESTS | 548 | ||
DIFFERENTIAL DIAGNOSIS | 548 | ||
DIAGNOSTIC CHECKLIST | 549 | ||
SELECTED REFERENCES | 549 | ||
Perineurioma | 560 | ||
Chapter 89.\rIntraneural Perineurioma | 560 | ||
TERMINOLOGY | 561 | ||
ETIOLOGY/PATHOGENESIS | 561 | ||
CLINICAL ISSUES | 561 | ||
IMAGING | 561 | ||
MACROSCOPIC | 561 | ||
MICROSCOPIC | 561 | ||
ANCILLARY TESTS | 561 | ||
DIFFERENTIAL DIAGNOSIS | 561 | ||
SELECTED REFERENCES | 561 | ||
Chapter 90.\rSoft Tissue Perineurioma | 564 | ||
TERMINOLOGY | 565 | ||
ETIOLOGY/PATHOGENESIS | 565 | ||
CLINICAL ISSUES | 565 | ||
IMAGING | 565 | ||
MACROSCOPIC | 565 | ||
MICROSCOPIC | 565 | ||
ANCILLARY TESTS | 565 | ||
DIFFERENTIAL DIAGNOSIS | 565 | ||
SELECTED REFERENCES | 565 | ||
Lipoma of 8th Cranial Nerve | 568 | ||
Chapter 91.\rLipoma of 8th Cranial Nerve | 568 | ||
TERMINOLOGY | 569 | ||
ETIOLOGY/PATHOGENESIS | 569 | ||
CLINICAL ISSUES | 569 | ||
IMAGING | 569 | ||
MICROSCOPIC | 569 | ||
ANCILLARY TESTS | 569 | ||
DIFFERENTIAL DIAGNOSIS | 569 | ||
DIAGNOSTIC CHECKLIST | 569 | ||
SELECTED REFERENCES | 569 | ||
SECTION 5: Familial Tumor Syndromes | 571 | ||
Neurofibromatosis | 572 | ||
Chapter 92.\rNeurofibromatosis 1 | 572 | ||
TERMINOLOGY | 573 | ||
ETIOLOGY/PATHOGENESIS | 573 | ||
CLINICAL ISSUES | 573 | ||
IMAGING | 573 | ||
SELECTED REFERENCES | 573 | ||
Chapter 93.\rNeurofibromatosis 2 | 574 | ||
TERMINOLOGY | 575 | ||
ETIOLOGY/PATHOGENESIS | 575 | ||
CLINICAL ISSUES | 575 | ||
IMAGING | 575 | ||
DIAGNOSTIC CHECKLIST | 575 | ||
SELECTED REFERENCES | 575 | ||
Chapter 94.\rSchwannomatosis | 576 | ||
TERMINOLOGY | 577 | ||
ETIOLOGY/PATHOGENESIS | 577 | ||
CLINICAL ISSUES | 577 | ||
IMAGING | 577 | ||
MACROSCOPIC | 577 | ||
MICROSCOPIC | 577 | ||
ANCILLARY TESTS | 577 | ||
DIFFERENTIAL DIAGNOSIS | 577 | ||
SELECTED REFERENCES | 577 | ||
Other | 578 | ||
Chapter 95.\rvon Hippel-Lindau Syndrome | 578 | ||
TERMINOLOGY | 579 | ||
CLINICAL ISSUES | 579 | ||
IMAGING | 579 | ||
ANCILLARY TESTS | 579 | ||
SELECTED REFERENCES | 579 | ||
Chapter 96.\rTuberous Sclerosis Complex | 580 | ||
TERMINOLOGY | 581 | ||
CLINICAL ISSUES | 581 | ||
IMAGING | 581 | ||
MACROSCOPIC | 581 | ||
MICROSCOPIC | 581 | ||
ANCILLARY TESTS | 581 | ||
SELECTED REFERENCES | 581 | ||
Chapter 97.\rTurcot Syndrome | 582 | ||
TERMINOLOGY | 583 | ||
ETIOLOGY/PATHOGENESIS | 583 | ||
CLINICAL ISSUES | 583 | ||
MACROSCOPIC | 583 | ||
MICROSCOPIC | 583 | ||
ANCILLARY TESTS | 583 | ||
DIFFERENTIAL DIAGNOSIS | 583 | ||
SELECTED REFERENCES | 583 | ||
Part II: Nonneoplastic | 585 | ||
SECTION 1: Benign Cysts | 585 | ||
Chapter 98.\rArachnoid Cyst | 586 | ||
TERMINOLOGY | 587 | ||
ETIOLOGY/PATHOGENESIS | 587 | ||
CLINICAL ISSUES | 587 | ||
IMAGING | 587 | ||
MACROSCOPIC | 587 | ||
MICROSCOPIC | 587 | ||
ANCILLARY TESTS | 587 | ||
DIFFERENTIAL DIAGNOSIS | 587 | ||
SELECTED REFERENCES | 587 | ||
Chapter 99.\rEpidermoid and Dermoid Cysts | 588 | ||
TERMINOLOGY | 589 | ||
CLINICAL ISSUES | 589 | ||
IMAGING | 589 | ||
MACROSCOPIC | 589 | ||
MICROSCOPIC | 589 | ||
ANCILLARY TESTS | 589 | ||
DIFFERENTIAL DIAGNOSIS | 589 | ||
DIAGNOSTIC CHECKLIST | 589 | ||
SELECTED REFERENCES | 589 | ||
Chapter 100.\rColloid Cyst | 592 | ||
TERMINOLOGY | 593 | ||
CLINICAL ISSUES | 593 | ||
IMAGING | 593 | ||
MACROSCOPIC | 593 | ||
MICROSCOPIC | 593 | ||
ANCILLARY TESTS | 593 | ||
DIFFERENTIAL DIAGNOSIS | 593 | ||
DIAGNOSTIC CHECKLIST | 593 | ||
SELECTED REFERENCES | 593 | ||
Chapter 101.\rRathke Cleft Cyst | 596 | ||
TERMINOLOGY | 597 | ||
CLINICAL ISSUES | 597 | ||
IMAGING | 597 | ||
MACROSCOPIC | 597 | ||
MICROSCOPIC | 597 | ||
ANCILLARY TESTS | 597 | ||
DIFFERENTIAL DIAGNOSIS | 597 | ||
DIAGNOSTIC CHECKLIST | 597 | ||
SELECTED REFERENCES | 597 | ||
Chapter 102.\rEndodermal Cyst | 600 | ||
TERMINOLOGY | 601 | ||
CLINICAL ISSUES | 601 | ||
IMAGING | 601 | ||
MACROSCOPIC | 601 | ||
MICROSCOPIC | 601 | ||
ANCILLARY TESTS | 601 | ||
DIFFERENTIAL DIAGNOSIS | 601 | ||
SELECTED REFERENCES | 601 | ||
Chapter 103.\rEpendymal Cyst | 604 | ||
TERMINOLOGY | 605 | ||
CLINICAL ISSUES | 605 | ||
IMAGING | 605 | ||
MACROSCOPIC | 605 | ||
MICROSCOPIC | 605 | ||
ANCILLARY TESTS | 605 | ||
DIFFERENTIAL DIAGNOSIS | 605 | ||
DIAGNOSTIC CHECKLIST | 605 | ||
SELECTED REFERENCES | 605 | ||
Chapter 104.\rPineal Cyst | 606 | ||
TERMINOLOGY | 607 | ||
ETIOLOGY/PATHOGENESIS | 607 | ||
CLINICAL ISSUES | 607 | ||
IMAGING | 607 | ||
MACROSCOPIC | 607 | ||
MICROSCOPIC | 607 | ||
ANCILLARY TESTS | 607 | ||
DIFFERENTIAL DIAGNOSIS | 608 | ||
DIAGNOSTIC CHECKLIST | 608 | ||
SELECTED REFERENCES | 608 | ||
Chapter 105.\rFacet Joint Synovial Cyst | 612 | ||
TERMINOLOGY | 613 | ||
CLINICAL ISSUES | 613 | ||
IMAGING | 613 | ||
MACROSCOPIC | 613 | ||
MICROSCOPIC | 613 | ||
DIFFERENTIAL DIAGNOSIS | 613 | ||
DIAGNOSTIC CHECKLIST | 613 | ||
SELECTED REFERENCES | 613 | ||
SECTION 2: Infectious, Inflammatory, and Reactive Lesions | 615 | ||
Demyelinating Diseases | 616 | ||
Chapter 106.\rDemyelinating Disease (Multiple Sclerosis-Tumefactive Demyelination) | 616 | ||
TERMINOLOGY | 617 | ||
CLINICAL ISSUES | 617 | ||
IMAGING | 617 | ||
MACROSCOPIC | 617 | ||
MICROSCOPIC | 617 | ||
ANCILLARY TESTS | 618 | ||
DIFFERENTIAL DIAGNOSIS | 618 | ||
DIAGNOSTIC CHECKLIST | 618 | ||
SELECTED REFERENCES | 618 | ||
Bacterial Infections | 624 | ||
Chapter 107.\rAbscess and Cerebritis | 624 | ||
TERMINOLOGY | 625 | ||
ETIOLOGY/PATHOGENESIS | 625 | ||
CLINICAL ISSUES | 625 | ||
IMAGING | 625 | ||
MACROSCOPIC | 625 | ||
MICROSCOPIC | 625 | ||
DIFFERENTIAL DIAGNOSIS | 625 | ||
DIAGNOSTIC CHECKLIST | 625 | ||
SELECTED REFERENCES | 625 | ||
Chapter 108.\rWhipple Disease | 630 | ||
TERMINOLOGY | 631 | ||
ETIOLOGY/PATHOGENESIS | 631 | ||
CLINICAL ISSUES | 631 | ||
IMAGING | 631 | ||
MACROSCOPIC | 631 | ||
MICROSCOPIC | 631 | ||
ANCILLARY TESTS | 631 | ||
DIFFERENTIAL DIAGNOSIS | 631 | ||
DIAGNOSTIC CHECKLIST | 631 | ||
SELECTED REFERENCES | 631 | ||
Chapter 109.\rTuberculosis | 634 | ||
TERMINOLOGY | 635 | ||
ETIOLOGY/PATHOGENESIS | 635 | ||
CLINICAL ISSUES | 635 | ||
IMAGING | 635 | ||
MACROSCOPIC | 635 | ||
MICROSCOPIC | 635 | ||
ANCILLARY TESTS | 636 | ||
DIFFERENTIAL DIAGNOSIS | 636 | ||
DIAGNOSTIC CHECKLIST | 636 | ||
SELECTED REFERENCES | 636 | ||
Viral Infections | 640 | ||
Chapter 110.\rHerpes Simplex Encephalitis | 640 | ||
TERMINOLOGY | 641 | ||
ETIOLOGY/PATHOGENESIS | 641 | ||
CLINICAL ISSUES | 641 | ||
IMAGING | 641 | ||
MACROSCOPIC | 641 | ||
MICROSCOPIC | 641 | ||
ANCILLARY TESTS | 642 | ||
DIFFERENTIAL DIAGNOSIS | 642 | ||
DIAGNOSTIC CHECKLIST | 642 | ||
SELECTED REFERENCES | 642 | ||
Chapter 111.\rProgressive Multifocal Leukoencephalopathy | 646 | ||
TERMINOLOGY | 647 | ||
ETIOLOGY/PATHOGENESIS | 647 | ||
CLINICAL ISSUES | 647 | ||
IMAGING | 647 | ||
MACROSCOPIC | 647 | ||
MICROSCOPIC | 648 | ||
ANCILLARY TESTS | 648 | ||
DIFFERENTIAL DIAGNOSIS | 648 | ||
DIAGNOSTIC CHECKLIST | 649 | ||
SELECTED REFERENCES | 649 | ||
Chapter 112.\rHIV Encephalitis | 654 | ||
TERMINOLOGY | 655 | ||
ETIOLOGY/PATHOGENESIS | 655 | ||
CLINICAL ISSUES | 655 | ||
IMAGING | 655 | ||
MACROSCOPIC | 655 | ||
MICROSCOPIC | 655 | ||
ANCILLARY TESTS | 656 | ||
DIFFERENTIAL DIAGNOSIS | 656 | ||
DIAGNOSTIC CHECKLIST | 656 | ||
SELECTED REFERENCES | 656 | ||
Chapter 113.\rOther Viral Infections | 658 | ||
TERMINOLOGY | 659 | ||
ETIOLOGY/PATHOGENESIS | 659 | ||
CLINICAL ISSUES | 659 | ||
IMAGING | 659 | ||
MACROSCOPIC | 660 | ||
MICROSCOPIC | 660 | ||
ANCILLARY TESTS | 660 | ||
DIFFERENTIAL DIAGNOSIS | 661 | ||
DIAGNOSTIC CHECKLIST | 661 | ||
SELECTED REFERENCES | 661 | ||
Fungal Infections | 668 | ||
Chapter 114.\rFungal Infections | 668 | ||
TERMINOLOGY | 669 | ||
ETIOLOGY/PATHOGENESIS | 669 | ||
CLINICAL ISSUES | 669 | ||
MACROSCOPIC | 669 | ||
MICROSCOPIC | 669 | ||
ANCILLARY TESTS | 671 | ||
DIFFERENTIAL DIAGNOSIS | 671 | ||
DIAGNOSTIC CHECKLIST | 671 | ||
SELECTED REFERENCES | 671 | ||
Protozoal and Parasitic Infections | 680 | ||
Chapter 115.\rToxoplasmosis | 680 | ||
TERMINOLOGY | 681 | ||
ETIOLOGY/PATHOGENESIS | 681 | ||
CLINICAL ISSUES | 681 | ||
IMAGING | 681 | ||
MACROSCOPIC | 681 | ||
MICROSCOPIC | 681 | ||
ANCILLARY TESTS | 682 | ||
DIFFERENTIAL DIAGNOSIS | 682 | ||
DIAGNOSTIC CHECKLIST | 682 | ||
SELECTED REFERENCES | 682 | ||
Chapter 116.\rAmebiasis | 684 | ||
TERMINOLOGY | 685 | ||
ETIOLOGY/PATHOGENESIS | 685 | ||
CLINICAL ISSUES | 685 | ||
IMAGING | 686 | ||
MACROSCOPIC | 686 | ||
MICROSCOPIC | 686 | ||
DIFFERENTIAL DIAGNOSIS | 686 | ||
DIAGNOSTIC CHECKLIST | 686 | ||
SELECTED REFERENCES | 686 | ||
Chapter 117.\rCysticercosis | 690 | ||
TERMINOLOGY | 691 | ||
ETIOLOGY/PATHOGENESIS | 691 | ||
CLINICAL ISSUES | 691 | ||
MACROSCOPIC | 691 | ||
MICROSCOPIC | 691 | ||
DIFFERENTIAL DIAGNOSIS | 691 | ||
DIAGNOSTIC CHECKLIST | 691 | ||
SELECTED REFERENCES | 691 | ||
Chapter 118.\rMiscellaneous Parasitic Infections | 696 | ||
TERMINOLOGY | 697 | ||
ETIOLOGY/PATHOGENESIS | 697 | ||
CLINICAL ISSUES | 697 | ||
IMAGING | 698 | ||
MACROSCOPIC | 698 | ||
MICROSCOPIC | 698 | ||
DIFFERENTIAL DIAGNOSIS | 698 | ||
SELECTED REFERENCES | 698 | ||
Other Inflammatory Diseases | 702 | ||
Chapter 119.\rSarcoidosis | 702 | ||
TERMINOLOGY | 703 | ||
ETIOLOGY/PATHOGENESIS | 703 | ||
CLINICAL ISSUES | 703 | ||
IMAGING | 703 | ||
MACROSCOPIC | 703 | ||
MICROSCOPIC | 703 | ||
ANCILLARY TESTS | 704 | ||
DIFFERENTIAL DIAGNOSIS | 704 | ||
DIAGNOSTIC CHECKLIST | 704 | ||
SELECTED REFERENCES | 704 | ||
Chapter 120.\rRasmussen Encephalitis | 708 | ||
TERMINOLOGY | 709 | ||
ETIOLOGY/PATHOGENESIS | 709 | ||
CLINICAL ISSUES | 709 | ||
IMAGING | 710 | ||
MACROSCOPIC | 710 | ||
MICROSCOPIC | 710 | ||
ANCILLARY TESTS | 710 | ||
DIFFERENTIAL DIAGNOSIS | 710 | ||
DIAGNOSTIC CHECKLIST | 711 | ||
SELECTED REFERENCES | 711 | ||
Chapter 121.\rParaneoplastic Disease | 714 | ||
TERMINOLOGY | 715 | ||
ETIOLOGY/PATHOGENESIS | 715 | ||
CLINICAL ISSUES | 715 | ||
IMAGING | 715 | ||
MICROSCOPIC | 715 | ||
ANCILLARY TESTS | 715 | ||
DIFFERENTIAL DIAGNOSIS | 715 | ||
DIAGNOSTIC CHECKLIST | 715 | ||
SELECTED REFERENCES | 715 | ||
Chapter 122.\rTextiloma (Muslinoma, Gauzoma, Gossypiboma) | 716 | ||
TERMINOLOGY | 717 | ||
ETIOLOGY/PATHOGENESIS | 717 | ||
CLINICAL ISSUES | 717 | ||
IMAGING | 717 | ||
MACROSCOPIC | 717 | ||
MICROSCOPIC | 717 | ||
DIFFERENTIAL DIAGNOSIS | 717 | ||
SELECTED REFERENCES | 717 | ||
Chapter 123.\rInflammatory Pseudotumors | 722 | ||
TERMINOLOGY | 723 | ||
ETIOLOGY/PATHOGENESIS | 723 | ||
CLINICAL ISSUES | 723 | ||
IMAGING | 723 | ||
MICROSCOPIC | 723 | ||
DIFFERENTIAL DIAGNOSIS | 723 | ||
SELECTED REFERENCES | 723 | ||
Chapter 124.\rLymphocytic Hypophysitis | 724 | ||
TERMINOLOGY | 725 | ||
ETIOLOGY/PATHOGENESIS | 725 | ||
CLINICAL ISSUES | 725 | ||
IMAGING | 725 | ||
MACROSCOPIC | 725 | ||
MICROSCOPIC | 725 | ||
ANCILLARY TESTS | 726 | ||
DIFFERENTIAL DIAGNOSIS | 726 | ||
DIAGNOSTIC CHECKLIST | 726 | ||
SELECTED REFERENCES | 726 | ||
Chapter 125.\rRosai-Dorfman Disease | 728 | ||
TERMINOLOGY | 729 | ||
ETIOLOGY/PATHOGENESIS | 729 | ||
CLINICAL ISSUES | 729 | ||
IMAGING | 729 | ||
MACROSCOPIC | 729 | ||
MICROSCOPIC | 729 | ||
ANCILLARY TESTS | 729 | ||
DIFFERENTIAL DIAGNOSIS | 729 | ||
DIAGNOSTIC CHECKLIST | 729 | ||
SELECTED REFERENCES | 729 | ||
Reactive Conditions and Noninflammatory Pseudoneoplasms | 738 | ||
Chapter 126.\rMeningioangiomatosis | 732 | ||
TERMINOLOGY | 733 | ||
CLINICAL ISSUES | 733 | ||
IMAGING | 733 | ||
MACROSCOPIC | 733 | ||
MICROSCOPIC | 733 | ||
ANCILLARY TESTS | 733 | ||
DIFFERENTIAL DIAGNOSIS | 734 | ||
DIAGNOSTIC CHECKLIST | 734 | ||
SELECTED REFERENCES | 734 | ||
Chapter 127.\rMeningeal Response to Intracranial Hypotension | 738 | ||
ETIOLOGY/PATHOGENESIS | 739 | ||
CLINICAL ISSUES | 739 | ||
IMAGING | 739 | ||
MACROSCOPIC | 739 | ||
MICROSCOPIC | 739 | ||
DIFFERENTIAL DIAGNOSIS | 739 | ||
DIAGNOSTIC CHECKLIST | 739 | ||
SELECTED REFERENCES | 739 | ||
Chapter 128.\rRadiation Necrosis | 740 | ||
TERMINOLOGY | 741 | ||
ETIOLOGY/PATHOGENESIS | 741 | ||
CLINICAL ISSUES | 741 | ||
IMAGING | 741 | ||
MACROSCOPIC | 741 | ||
MICROSCOPIC | 741 | ||
DIFFERENTIAL DIAGNOSIS | 742 | ||
DIAGNOSTIC CHECKLIST | 742 | ||
SELECTED REFERENCES | 742 | ||
Chapter 129.\rCalcifying Pseudoneoplasm of the Neuraxis | 748 | ||
TERMINOLOGY | 749 | ||
ETIOLOGY/PATHOGENESIS | 749 | ||
CLINICAL ISSUES | 749 | ||
IMAGING | 749 | ||
MACROSCOPIC | 749 | ||
MICROSCOPIC | 749 | ||
ANCILLARY TESTS | 749 | ||
DIFFERENTIAL DIAGNOSIS | 749 | ||
SELECTED REFERENCES | 749 | ||
SECTION 3: Vascular Diseases | 753 | ||
Vascular Malformations and Neoplasms | 754 | ||
Chapter 130. Telangiectasis\r | 754 | ||
TERMINOLOGY | 755 | ||
ETIOLOGY/PATHOGENESIS | 755 | ||
CLINICAL ISSUES | 755 | ||
IMAGING | 755 | ||
MACROSCOPIC | 755 | ||
MICROSCOPIC | 755 | ||
DIFFERENTIAL DIAGNOSIS | 755 | ||
DIAGNOSTIC CHECKLIST | 755 | ||
SELECTED REFERENCES | 755 | ||
Chapter 131.\rCavernous Angioma | 758 | ||
TERMINOLOGY | 759 | ||
ETIOLOGY/PATHOGENESIS | 759 | ||
CLINICAL ISSUES | 759 | ||
IMAGING | 759 | ||
MACROSCOPIC | 759 | ||
MICROSCOPIC | 759 | ||
DIFFERENTIAL DIAGNOSIS | 759 | ||
SELECTED REFERENCES | 759 | ||
Chapter 132. Arteriovenous Malformation | 762 | ||
TERMINOLOGY | 763 | ||
ETIOLOGY/PATHOGENESIS | 763 | ||
CLINICAL ISSUES | 763 | ||
IMAGING | 763 | ||
MACROSCOPIC | 763 | ||
MICROSCOPIC | 764 | ||
DIFFERENTIAL DIAGNOSIS | 764 | ||
DIAGNOSTIC CHECKLIST | 764 | ||
SELECTED REFERENCES | 764 | ||
Chapter 133. Capillary Hemangioma | 768 | ||
TERMINOLOGY | 769 | ||
CLINICAL ISSUES | 769 | ||
IMAGING | 769 | ||
MACROSCOPIC | 769 | ||
MICROSCOPIC | 769 | ||
ANCILLARY TESTS | 769 | ||
DIFFERENTIAL DIAGNOSIS | 769 | ||
DIAGNOSTIC CHECKLIST | 769 | ||
SELECTED REFERENCES | 769 | ||
Vascular Lesions | 770 | ||
Chapter 134.\rSubdural Hematoma | 770 | ||
TERMINOLOGY | 771 | ||
ETIOLOGY/PATHOGENESIS | 771 | ||
CLINICAL ISSUES | 771 | ||
IMAGING | 771 | ||
MACROSCOPIC | 771 | ||
MICROSCOPIC | 771 | ||
DIAGNOSTIC CHECKLIST | 771 | ||
SELECTED REFERENCES | 771 | ||
Chapter 135.\rInfarct | 776 | ||
TERMINOLOGY | 777 | ||
ETIOLOGY/PATHOGENESIS | 777 | ||
CLINICAL ISSUES | 777 | ||
IMAGING | 777 | ||
MACROSCOPIC | 778 | ||
MICROSCOPIC | 778 | ||
ANCILLARY TESTS | 778 | ||
DIFFERENTIAL DIAGNOSIS | 778 | ||
DIAGNOSTIC CHECKLIST | 778 | ||
SELECTED REFERENCES | 778 | ||
Vasculitis and Vasculopathy | 784 | ||
Chapter 136.\rPrimary Angiitis of Central Nervous System | 784 | ||
TERMINOLOGY | 785 | ||
ETIOLOGY/PATHOGENESIS | 785 | ||
CLINICAL ISSUES | 785 | ||
IMAGING | 785 | ||
MACROSCOPIC | 785 | ||
MICROSCOPIC | 785 | ||
ANCILLARY TESTS | 786 | ||
DIFFERENTIAL DIAGNOSIS | 786 | ||
DIAGNOSTIC CHECKLIST | 787 | ||
SELECTED REFERENCES | 787 | ||
Chapter 137.\rAmyloid (Congophilic) Angiopathy | 792 | ||
TERMINOLOGY | 793 | ||
ETIOLOGY/PATHOGENESIS | 793 | ||
CLINICAL ISSUES | 793 | ||
IMAGING | 793 | ||
MACROSCOPIC | 793 | ||
MICROSCOPIC | 793 | ||
DIFFERENTIAL DIAGNOSIS | 794 | ||
DIAGNOSTIC CHECKLIST | 794 | ||
SELECTED REFERENCES | 794 | ||
SECTION 4: Cortical Dysplasia | 799 | ||
Chapter 138.\rCortical Dysplasia | 800 | ||
TERMINOLOGY | 801 | ||
ETIOLOGY/PATHOGENESIS | 801 | ||
CLINICAL ISSUES | 801 | ||
IMAGING | 801 | ||
MICROSCOPIC | 801 | ||
ANCILLARY TESTS | 801 | ||
DIFFERENTIAL DIAGNOSIS | 801 | ||
SELECTED REFERENCES | 801 | ||
INDEX | I-i |