Additional Information
Book Details
Abstract
Part of the highly regarded Diagnostic Pathology series, this updated volume by Drs. Mahul B. Amin and Satish K. Tickoo is a visually stunning, easy-to-use reference covering all aspects of genitourinary pathology. Outstanding images – including gross pathology, a wide range of stains, and detailed medical illustrations – make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This 2nd Edition incorporates the most recent clinical, pathological, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice.
- Nearly 200 diagnoses, richly illustrated and extensively annotated, cover diseases of the kidney, prostate, bladder, testis, and penis.
- High-quality, carefully annotated images provide clinically and diagnostically important information, including difficult issues of grading and staging, and diagnostic dilemmas not covered in depth elsewhere.
- Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, and annotated images.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Diagnostic Pathology: Genitourinary | iii | ||
| Copyright Page | iv | ||
| Table of Contents | xiv | ||
| Dedications | v | ||
| Contributing Authors | vi | ||
| Preface | viii | ||
| Acknowledgments | xi | ||
| Sections | xiii | ||
| SECTION 1: Kidney Tumors and Tumor-Like Conditions | 2 | ||
| Introduction and Overview | 4 | ||
| Chapter 1.\rClassification of Kidney Tumors and Tumor-Like Lesions | 4 | ||
| NONNEOPLASTIC LESIONS | 4 | ||
| NEOPLASMS | 4 | ||
| Chapter 2.\rIntroduction to Renal Cell Tumors | 6 | ||
| TERMINOLOGY | 6 | ||
| EPIDEMIOLOGY | 6 | ||
| CLINICAL IMPLICATIONS | 6 | ||
| SELECTED REFERENCES | 8 | ||
| Familial Cancer Syndromes | 12 | ||
| Chapter 3.\rvon Hippel-Lindau Syndrome | 12 | ||
| TERMINOLOGY | 13 | ||
| ETIOLOGY/PATHOGENESIS | 13 | ||
| CLINICAL ISSUES | 13 | ||
| MACROSCOPIC | 13 | ||
| MICROSCOPIC | 14 | ||
| DIFFERENTIAL DIAGNOSIS | 14 | ||
| SELECTED REFERENCES | 14 | ||
| Chapter 4. Birt-Hogg-Dubé Syndrome | 16 | ||
| TERMINOLOGY | 17 | ||
| ETIOLOGY/PATHOGENESIS | 17 | ||
| CLINICAL ISSUES | 17 | ||
| MACROSCOPIC | 17 | ||
| MICROSCOPIC | 17 | ||
| ANCILLARY TESTS | 18 | ||
| DIFFERENTIAL DIAGNOSIS | 18 | ||
| DIAGNOSTIC CHECKLIST | 18 | ||
| SELECTED REFERENCES | 18 | ||
| Chapter 5. Hereditary Leiomyomatosis Renal Cell Carcinoma Syndrome | 20 | ||
| TERMINOLOGY | 21 | ||
| ETIOLOGY/PATHOGENESIS | 21 | ||
| CLINICAL ISSUES | 21 | ||
| MACROSCOPIC | 21 | ||
| MICROSCOPIC | 21 | ||
| ANCILLARY TESTS | 22 | ||
| DIFFERENTIAL DIAGNOSIS | 22 | ||
| DIAGNOSTIC CHECKLIST | 22 | ||
| SELECTED REFERENCES | 22 | ||
| Chapter 6. Tuberous Sclerosis Complex | 24 | ||
| TERMINOLOGY | 25 | ||
| ETIOLOGY/PATHOGENESIS | 25 | ||
| CLINICAL ISSUES | 25 | ||
| MICROSCOPIC | 25 | ||
| ANCILLARY TESTS | 26 | ||
| DIFFERENTIAL DIAGNOSIS | 26 | ||
| DIAGNOSTIC CHECKLIST | 26 | ||
| SELECTED REFERENCES | 26 | ||
| Chapter 7. Succinate Dehydrogenase Complex Deficiency Syndrome | 28 | ||
| TERMINOLOGY | 29 | ||
| ETIOLOGY/PATHOGENESIS | 29 | ||
| CLINICAL ISSUES | 29 | ||
| MACROSCOPIC | 29 | ||
| MICROSCOPIC | 29 | ||
| ANCILLARY TESTS | 30 | ||
| DIFFERENTIAL DIAGNOSIS | 30 | ||
| DIAGNOSTIC CHECKLIST | 30 | ||
| SELECTED REFERENCES | 30 | ||
| Chapter 8. Hereditary Papillary Renal Cancer and Miscellaneous Other Familial Cancer Syndromes | 32 | ||
| TERMINOLOGY | 33 | ||
| ETIOLOGY/PATHOGENESIS | 33 | ||
| CLINICAL ISSUES | 33 | ||
| MACROSCOPIC | 34 | ||
| MICROSCOPIC | 34 | ||
| DIFFERENTIAL DIAGNOSIS | 34 | ||
| SELECTED REFERENCES | 34 | ||
| Nonneoplastic Lesions | 38 | ||
| Chapter 9. Renal Tuberculosis, Xanthogranulomatous Pyelonephritis, Renal Malakoplakia | 38 | ||
| TERMINOLOGY | 39 | ||
| ETIOLOGY/PATHOGENESIS | 39 | ||
| CLINICAL ISSUES | 39 | ||
| MACROSCOPIC | 39 | ||
| MICROSCOPIC | 40 | ||
| DIFFERENTIAL DIAGNOSIS | 40 | ||
| DIAGNOSTIC CHECKLIST | 40 | ||
| SELECTED REFERENCES | 40 | ||
| Renal Cell Tumors, Benign | 44 | ||
| Chapter 10. Papillary Adenoma | 44 | ||
| TERMINOLOGY | 45 | ||
| ETIOLOGY/PATHOGENESIS | 45 | ||
| CLINICAL ISSUES | 45 | ||
| MACROSCOPIC | 45 | ||
| MICROSCOPIC | 45 | ||
| ANCILLARY TESTS | 45 | ||
| DIFFERENTIAL DIAGNOSIS | 45 | ||
| DIAGNOSTIC CHECKLIST | 45 | ||
| SELECTED REFERENCES | 45 | ||
| Chapter 11. Renal Oncocytoma | 48 | ||
| TERMINOLOGY | 49 | ||
| ETIOLOGY/PATHOGENESIS | 49 | ||
| CLINICAL ISSUES | 49 | ||
| MACROSCOPIC | 49 | ||
| MICROSCOPIC | 49 | ||
| ANCILLARY TESTS | 50 | ||
| DIFFERENTIAL DIAGNOSIS | 50 | ||
| DIAGNOSTIC CHECKLIST | 50 | ||
| SELECTED REFERENCES | 50 | ||
| Renal Cell Carcinoma | 54 | ||
| Chapter 12. Clear Cell Renal Cell Carcinoma | 54 | ||
| TERMINOLOGY | 55 | ||
| ETIOLOGY/PATHOGENESIS | 55 | ||
| CLINICAL ISSUES | 55 | ||
| MACROSCOPIC | 56 | ||
| MICROSCOPIC | 56 | ||
| ANCILLARY TESTS | 56 | ||
| DIFFERENTIAL DIAGNOSIS | 56 | ||
| DIAGNOSTIC CHECKLIST | 57 | ||
| SELECTED REFERENCES | 57 | ||
| Chapter 13. Multilocular Cystic Clear Cell Renal Cell Neoplasm of Low Malignant Potential | 64 | ||
| TERMINOLOGY | 65 | ||
| ETIOLOGY/PATHOGENESIS | 65 | ||
| CLINICAL ISSUES | 65 | ||
| MACROSCOPIC | 65 | ||
| MICROSCOPIC | 65 | ||
| ANCILLARY TESTS | 65 | ||
| DIFFERENTIAL DIAGNOSIS | 65 | ||
| SELECTED REFERENCES | 65 | ||
| Chapter 14. Transcription Elongation Factor B (TCEB1)-Mutated Renal Cell Carcinoma | 68 | ||
| TERMINOLOGY | 69 | ||
| ETIOLOGY/PATHOGENESIS | 69 | ||
| CLINICAL ISSUES | 69 | ||
| MACROSCOPIC | 69 | ||
| MICROSCOPIC | 69 | ||
| ANCILLARY TESTS | 69 | ||
| DIFFERENTIAL DIAGNOSIS | 69 | ||
| SELECTED REFERENCES | 69 | ||
| Chapter 15. Clear Cell Papillary Renal Cell Carcinoma | 72 | ||
| TERMINOLOGY | 73 | ||
| ETIOLOGY/PATHOGENESIS | 73 | ||
| CLINICAL ISSUES | 73 | ||
| IMAGING | 73 | ||
| MACROSCOPIC | 73 | ||
| MICROSCOPIC | 73 | ||
| ANCILLARY TESTS | 74 | ||
| DIFFERENTIAL DIAGNOSIS | 74 | ||
| SELECTED REFERENCES | 74 | ||
| Chapter 16. Papillary Renal Cell Carcinoma | 80 | ||
| TERMINOLOGY | 81 | ||
| ETIOLOGY/PATHOGENESIS | 81 | ||
| CLINICAL ISSUES | 81 | ||
| MACROSCOPIC | 81 | ||
| MICROSCOPIC | 81 | ||
| ANCILLARY TESTS | 82 | ||
| DIFFERENTIAL DIAGNOSIS | 82 | ||
| DIAGNOSTIC CHECKLIST | 83 | ||
| SELECTED REFERENCES | 83 | ||
| Chapter 17. Chromophobe Renal Cell Carcinoma | 90 | ||
| TERMINOLOGY | 91 | ||
| ETIOLOGY/PATHOGENESIS | 91 | ||
| CLINICAL ISSUES | 91 | ||
| IMAGING | 91 | ||
| MACROSCOPIC | 91 | ||
| MICROSCOPIC | 92 | ||
| ANCILLARY TESTS | 92 | ||
| DIFFERENTIAL DIAGNOSIS | 92 | ||
| DIAGNOSTIC CHECKLIST | 93 | ||
| SELECTED REFERENCES | 93 | ||
| Chapter 18. Collecting Duct Carcinoma | 98 | ||
| TERMINOLOGY | 99 | ||
| ETIOLOGY/PATHOGENESIS | 99 | ||
| CLINICAL ISSUES | 99 | ||
| MACROSCOPIC | 99 | ||
| MICROSCOPIC | 99 | ||
| ANCILLARY TESTS | 100 | ||
| DIFFERENTIAL DIAGNOSIS | 100 | ||
| DIAGNOSTIC CHECKLIST | 100 | ||
| SELECTED REFERENCES | 100 | ||
| Chapter 19. Renal Medullary Carcinoma | 104 | ||
| TERMINOLOGY | 105 | ||
| ETIOLOGY/PATHOGENESIS | 105 | ||
| CLINICAL ISSUES | 105 | ||
| MACROSCOPIC | 105 | ||
| MICROSCOPIC | 105 | ||
| ANCILLARY TESTS | 106 | ||
| DIFFERENTIAL DIAGNOSIS | 106 | ||
| DIAGNOSTIC CHECKLIST | 106 | ||
| SELECTED REFERENCES | 106 | ||
| Chapter 20. MiTF/TFE Family Translocation-Associated Carcinoma | 110 | ||
| TERMINOLOGY | 111 | ||
| ETIOLOGY/PATHOGENESIS | 111 | ||
| CLINICAL ISSUES | 111 | ||
| MACROSCOPIC | 112 | ||
| MICROSCOPIC | 112 | ||
| ANCILLARY TESTS | 112 | ||
| DIFFERENTIAL DIAGNOSIS | 113 | ||
| DIAGNOSTIC CHECKLIST | 113 | ||
| SELECTED REFERENCES | 113 | ||
| Chapter 21. Mucinous Tubular and Spindle Cell Carcinoma | 118 | ||
| TERMINOLOGY | 119 | ||
| ETIOLOGY/PATHOGENESIS | 119 | ||
| CLINICAL ISSUES | 119 | ||
| MACROSCOPIC | 119 | ||
| MICROSCOPIC | 119 | ||
| ANCILLARY TESTS | 119 | ||
| DIFFERENTIAL DIAGNOSIS | 119 | ||
| DIAGNOSTIC CHECKLIST | 120 | ||
| SELECTED REFERENCES | 120 | ||
| Chapter 22. Tubulocystic Carcinoma | 124 | ||
| TERMINOLOGY | 125 | ||
| ETIOLOGY/PATHOGENESIS | 125 | ||
| CLINICAL ISSUES | 125 | ||
| MACROSCOPIC | 125 | ||
| MICROSCOPIC | 125 | ||
| ANCILLARY TESTS | 125 | ||
| DIFFERENTIAL DIAGNOSIS | 125 | ||
| SELECTED REFERENCES | 125 | ||
| Chapter 23. Thyroid-Like Follicular Carcinoma of Kidney | 128 | ||
| TERMINOLOGY | 129 | ||
| ETIOLOGY/PATHOGENESIS | 129 | ||
| CLINICAL ISSUES | 129 | ||
| MACROSCOPIC | 129 | ||
| MICROSCOPIC | 129 | ||
| ANCILLARY TESTS | 129 | ||
| DIFFERENTIAL DIAGNOSIS | 129 | ||
| DIAGNOSTIC CHECKLIST | 129 | ||
| SELECTED REFERENCES | 129 | ||
| Chapter 24. Acquired Cystic Disease-Associated Renal Cell Carcinoma | 132 | ||
| TERMINOLOGY | 133 | ||
| ETIOLOGY/PATHOGENESIS | 133 | ||
| CLINICAL ISSUES | 133 | ||
| MACROSCOPIC | 133 | ||
| MICROSCOPIC | 133 | ||
| ANCILLARY TESTS | 134 | ||
| DIFFERENTIAL DIAGNOSIS | 134 | ||
| DIAGNOSTIC CHECKLIST | 134 | ||
| SELECTED REFERENCES | 134 | ||
| Chapter 25. Subsequent Second Tumors | 138 | ||
| TERMINOLOGY | 139 | ||
| ETIOLOGY/PATHOGENESIS | 139 | ||
| CLINICAL ISSUES | 139 | ||
| MACROSCOPIC | 139 | ||
| MICROSCOPIC | 139 | ||
| SELECTED REFERENCES | 139 | ||
| Chapter 26. Renal Cell Carcinoma, Unclassified | 142 | ||
| TERMINOLOGY | 143 | ||
| ETIOLOGY/PATHOGENESIS | 143 | ||
| CLINICAL ISSUES | 143 | ||
| MACROSCOPIC | 143 | ||
| MICROSCOPIC | 143 | ||
| DIFFERENTIAL DIAGNOSIS | 143 | ||
| SELECTED REFERENCES | 143 | ||
| Metanephric Tumors | 146 | ||
| Chapter 27. Metanephric Adenoma | 146 | ||
| TERMINOLOGY | 147 | ||
| ETIOLOGY/PATHOGENESIS | 147 | ||
| CLINICAL ISSUES | 147 | ||
| IMAGING | 147 | ||
| MACROSCOPIC | 147 | ||
| MICROSCOPIC | 147 | ||
| ANCILLARY TESTS | 148 | ||
| DIFFERENTIAL DIAGNOSIS | 148 | ||
| DIAGNOSTIC CHECKLIST | 148 | ||
| SELECTED REFERENCES | 148 | ||
| Chapter 28. Metanephric Tumors Other Than Metanephric Adenoma | 152 | ||
| TERMINOLOGY | 153 | ||
| ETIOLOGY/PATHOGENESIS | 153 | ||
| CLINICAL ISSUES | 153 | ||
| MACROSCOPIC | 153 | ||
| MICROSCOPIC | 153 | ||
| ANCILLARY TESTS | 153 | ||
| DIFFERENTIAL DIAGNOSIS | 153 | ||
| DIAGNOSTIC CHECKLIST | 153 | ||
| SELECTED REFERENCES | 153 | ||
| Nephroblastic Tumors | 156 | ||
| Chapter 29. Nephrogenic Rests | 156 | ||
| TERMINOLOGY | 157 | ||
| ETIOLOGY/PATHOGENESIS | 157 | ||
| CLINICAL ISSUES | 157 | ||
| MICROSCOPIC | 157 | ||
| DIFFERENTIAL DIAGNOSIS | 157 | ||
| DIAGNOSTIC CHECKLIST | 157 | ||
| SELECTED REFERENCES | 157 | ||
| Chapter 30. Nephroblastoma (Wilms Tumor) | 160 | ||
| TERMINOLOGY | 161 | ||
| ETIOLOGY/PATHOGENESIS | 161 | ||
| CLINICAL ISSUES | 161 | ||
| MACROSCOPIC | 161 | ||
| MICROSCOPIC | 162 | ||
| ANCILLARY TESTS | 162 | ||
| DIFFERENTIAL DIAGNOSIS | 162 | ||
| DIAGNOSTIC CHECKLIST | 163 | ||
| SELECTED REFERENCES | 163 | ||
| Chapter 31. Cystic Partially Differentiated Nephroblastoma | 170 | ||
| TERMINOLOGY | 171 | ||
| CLINICAL ISSUES | 171 | ||
| MACROSCOPIC | 171 | ||
| MICROSCOPIC | 171 | ||
| DIFFERENTIAL DIAGNOSIS | 171 | ||
| SELECTED REFERENCES | 171 | ||
| Mesenchymal Tumors | 172 | ||
| Chapter 32. Angiomyolipoma | 172 | ||
| TERMINOLOGY | 173 | ||
| ETIOLOGY/PATHOGENESIS | 173 | ||
| CLINICAL ISSUES | 173 | ||
| IMAGING | 173 | ||
| MACROSCOPIC | 173 | ||
| MICROSCOPIC | 173 | ||
| ANCILLARY TESTS | 174 | ||
| DIFFERENTIAL DIAGNOSIS | 174 | ||
| DIAGNOSTIC CHECKLIST | 174 | ||
| SELECTED REFERENCES | 174 | ||
| Chapter 33. Epithelioid Angiomyolipoma | 178 | ||
| TERMINOLOGY | 179 | ||
| ETIOLOGY/PATHOGENESIS | 179 | ||
| CLINICAL ISSUES | 179 | ||
| MACROSCOPIC | 179 | ||
| MICROSCOPIC | 179 | ||
| ANCILLARY TESTS | 180 | ||
| DIFFERENTIAL DIAGNOSIS | 180 | ||
| DIAGNOSTIC CHECKLIST | 180 | ||
| SELECTED REFERENCES | 180 | ||
| Chapter 34. Congenital Mesoblastic Nephroma | 184 | ||
| TERMINOLOGY | 185 | ||
| ETIOLOGY/PATHOGENESIS | 185 | ||
| CLINICAL ISSUES | 185 | ||
| MACROSCOPIC | 185 | ||
| MICROSCOPIC | 185 | ||
| DIFFERENTIAL DIAGNOSIS | 185 | ||
| DIAGNOSTIC CHECKLIST | 185 | ||
| SELECTED REFERENCES | 185 | ||
| Chapter 35. Clear Cell Sarcoma of Kidney | 188 | ||
| TERMINOLOGY | 189 | ||
| ETIOLOGY/PATHOGENESIS | 189 | ||
| CLINICAL ISSUES | 189 | ||
| MACROSCOPIC | 189 | ||
| MICROSCOPIC | 189 | ||
| ANCILLARY TESTS | 189 | ||
| DIFFERENTIAL DIAGNOSIS | 189 | ||
| DIAGNOSTIC CHECKLIST | 189 | ||
| SELECTED REFERENCES | 189 | ||
| Chapter 36. Malignant Rhabdoid Tumor | 192 | ||
| TERMINOLOGY | 193 | ||
| ETIOLOGY/PATHOGENESIS | 193 | ||
| CLINICAL ISSUES | 193 | ||
| MACROSCOPIC | 193 | ||
| MICROSCOPIC | 193 | ||
| ANCILLARY TESTS | 193 | ||
| DIFFERENTIAL DIAGNOSIS | 193 | ||
| DIAGNOSTIC CHECKLIST | 193 | ||
| SELECTED REFERENCES | 193 | ||
| Mixed Mesenchymal and Epithelial Tumors | 196 | ||
| Chapter 37. Mixed Epithelial and Stromal Tumor (MEST) Family Tumors and Pediatric Cystic Nephroma | 196 | ||
| TERMINOLOGY | 197 | ||
| ETIOLOGY/PATHOGENESIS | 197 | ||
| CLINICAL ISSUES | 197 | ||
| MACROSCOPIC | 197 | ||
| MICROSCOPIC | 197 | ||
| ANCILLARY TESTS | 198 | ||
| DIFFERENTIAL DIAGNOSIS | 198 | ||
| DIAGNOSTIC CHECKLIST | 198 | ||
| SELECTED REFERENCES | 198 | ||
| Chapter 38. Synovial Sarcoma | 204 | ||
| TERMINOLOGY | 205 | ||
| ETIOLOGY/PATHOGENESIS | 205 | ||
| CLINICAL ISSUES | 205 | ||
| MACROSCOPIC | 205 | ||
| MICROSCOPIC | 205 | ||
| ANCILLARY TESTS | 205 | ||
| DIFFERENTIAL DIAGNOSIS | 205 | ||
| DIAGNOSTIC CHECKLIST | 205 | ||
| SELECTED REFERENCES | 205 | ||
| Neuroendocrine Tumors | 208 | ||
| Chapter 39. Well-Differentiated Neuroendocrine Tumor (Carcinoid) and High-Grade Neuroendocrine Carcinoma | 208 | ||
| TERMINOLOGY | 209 | ||
| ETIOLOGY/PATHOGENESIS | 209 | ||
| CLINICAL ISSUES | 209 | ||
| MACROSCOPIC | 209 | ||
| MICROSCOPIC | 209 | ||
| DIFFERENTIAL DIAGNOSIS | 209 | ||
| DIAGNOSTIC CHECKLIST | 209 | ||
| SELECTED REFERENCES | 209 | ||
| Chapter 40. Primitive Neuroectodermal Tumor | 212 | ||
| TERMINOLOGY | 213 | ||
| ETIOLOGY/PATHOGENESIS | 213 | ||
| CLINICAL ISSUES | 213 | ||
| MACROSCOPIC | 213 | ||
| MICROSCOPIC | 213 | ||
| ANCILLARY TESTS | 213 | ||
| DIFFERENTIAL DIAGNOSIS | 213 | ||
| DIAGNOSTIC CHECKLIST | 213 | ||
| SELECTED REFERENCES | 213 | ||
| Hematopoietic Tumors | 216 | ||
| Chapter 41. Hematopoietic Tumors | 216 | ||
| TERMINOLOGY | 217 | ||
| ETIOLOGY/PATHOGENESIS | 217 | ||
| CLINICAL ISSUES | 217 | ||
| MACROSCOPIC | 218 | ||
| MICROSCOPIC | 218 | ||
| DIAGNOSTIC CHECKLIST | 218 | ||
| SELECTED REFERENCES | 218 | ||
| Metastatic and Other Tumors | 222 | ||
| Chapter 42. Juxtaglomerular Cell Tumor (Reninoma) | 222 | ||
| TERMINOLOGY | 223 | ||
| ETIOLOGY/PATHOGENESIS | 223 | ||
| CLINICAL ISSUES | 223 | ||
| IMAGING | 223 | ||
| MACROSCOPIC | 223 | ||
| MICROSCOPIC | 223 | ||
| ANCILLARY TESTS | 223 | ||
| DIFFERENTIAL DIAGNOSIS | 223 | ||
| SELECTED REFERENCES | 223 | ||
| Chapter 43. Renomedullary Interstitial Cell Tumor | 226 | ||
| TERMINOLOGY | 227 | ||
| ETIOLOGY/PATHOGENESIS | 227 | ||
| CLINICAL ISSUES | 227 | ||
| MACROSCOPIC | 227 | ||
| MICROSCOPIC | 227 | ||
| ANCILLARY TESTS | 227 | ||
| DIFFERENTIAL DIAGNOSIS | 227 | ||
| DIAGNOSTIC CHECKLIST | 227 | ||
| SELECTED REFERENCES | 227 | ||
| Chapter 44. Other Rare Tumors | 230 | ||
| TERMINOLOGY | 230 | ||
| EPIDEMIOLOGY | 230 | ||
| CLINICAL IMPLICATIONS | 230 | ||
| MACROSCOPIC | 231 | ||
| MICROSCOPIC | 231 | ||
| DIFFERENTIAL DIAGNOSIS | 231 | ||
| IMMUNOHISTOCHEMISTRY | 232 | ||
| DIAGNOSTIC CHECKLIST | 232 | ||
| SELECTED REFERENCES | 232 | ||
| Chapter 45. Metastatic Tumors | 238 | ||
| TERMINOLOGY | 239 | ||
| CLINICAL ISSUES | 239 | ||
| MACROSCOPIC | 239 | ||
| MICROSCOPIC | 239 | ||
| DIFFERENTIAL DIAGNOSIS | 239 | ||
| SELECTED REFERENCES | 239 | ||
| Immunohistochemical Profiles for Tumors Involving Kidney | 242 | ||
| Chapter 46. Immunohistochemistry, Kidney | 242 | ||
| SECTION 2:\rUrinary Bladder | 248 | ||
| Introduction and Overview | 250 | ||
| Chapter 47. Classification of Bladder Tumors and Tumor-Like Lesions | 250 | ||
| NONNEOPLASTIC LESIONS | 250 | ||
| NEOPLASMS | 250 | ||
| Microscopic Anatomy | 252 | ||
| Chapter 48. Microscopic Anatomy of Urinary Bladder | 252 | ||
| MACROSCOPIC | 252 | ||
| MICROSCOPIC | 252 | ||
| SELECTED REFERENCES | 253 | ||
| Chapter 49. Microscopic Anatomy of Urethra | 256 | ||
| MACROSCOPIC | 256 | ||
| MICROSCOPIC | 257 | ||
| SELECTED REFERENCES | 257 | ||
| Chapter 50. Microscopic Anatomy of Ureter | 260 | ||
| MACROSCOPIC | 260 | ||
| MICROSCOPIC | 260 | ||
| SELECTED REFERENCES | 260 | ||
| Chapter 51. Microscopic Anatomy of Renal Pelvis | 262 | ||
| MACROSCOPIC | 262 | ||
| MICROSCOPIC | 263 | ||
| SELECTED REFERENCES | 263 | ||
| Nonneoplastic Lesions of Urinary Tract | 266 | ||
| Chapter 52. Overview of Cystitis | 266 | ||
| TERMINOLOGY | 266 | ||
| CYSTITIS SUBTYPES | 266 | ||
| SELECTED REFERENCES | 268 | ||
| Chapter 53. Papillary-Polypoid Cystitis | 272 | ||
| TERMINOLOGY | 273 | ||
| ETIOLOGY/PATHOGENESIS | 273 | ||
| CLINICAL ISSUES | 273 | ||
| MACROSCOPIC | 273 | ||
| MICROSCOPIC | 273 | ||
| DIFFERENTIAL DIAGNOSIS | 273 | ||
| DIAGNOSTIC CHECKLIST | 274 | ||
| SELECTED REFERENCES | 274 | ||
| Chapter 54. Malakoplakia | 280 | ||
| TERMINOLOGY | 281 | ||
| ETIOLOGY/PATHOGENESIS | 281 | ||
| CLINICAL ISSUES | 281 | ||
| MACROSCOPIC | 281 | ||
| MICROSCOPIC | 281 | ||
| ANCILLARY TESTS | 281 | ||
| DIFFERENTIAL DIAGNOSIS | 281 | ||
| DIAGNOSTIC CHECKLIST | 281 | ||
| SELECTED REFERENCES | 281 | ||
| Chapter 55. Schistosomiasis | 286 | ||
| TERMINOLOGY | 287 | ||
| ETIOLOGY/PATHOGENESIS | 287 | ||
| CLINICAL ISSUES | 287 | ||
| MACROSCOPIC | 287 | ||
| MICROSCOPIC | 287 | ||
| DIFFERENTIAL DIAGNOSIS | 287 | ||
| DIAGNOSTIC CHECKLIST | 287 | ||
| SELECTED REFERENCES | 287 | ||
| Chapter 56. von Brunn Nests | 288 | ||
| TERMINOLOGY | 289 | ||
| ETIOLOGY/PATHOGENESIS | 289 | ||
| CLINICAL ISSUES | 289 | ||
| MACROSCOPIC | 289 | ||
| MICROSCOPIC | 289 | ||
| DIFFERENTIAL DIAGNOSIS | 289 | ||
| DIAGNOSTIC CHECKLIST | 289 | ||
| SELECTED REFERENCES | 289 | ||
| Chapter 57. Nephrogenic Adenoma (Metaplasia) | 294 | ||
| TERMINOLOGY | 295 | ||
| ETIOLOGY/PATHOGENESIS | 295 | ||
| CLINICAL ISSUES | 295 | ||
| MACROSCOPIC | 295 | ||
| MICROSCOPIC | 295 | ||
| ANCILLARY TESTS | 295 | ||
| DIFFERENTIAL DIAGNOSIS | 296 | ||
| DIAGNOSTIC CHECKLIST | 296 | ||
| SELECTED REFERENCES | 296 | ||
| Chapter 58. Fibroepithelial Polyp | 302 | ||
| TERMINOLOGY | 303 | ||
| CLINICAL ISSUES | 303 | ||
| MACROSCOPIC | 303 | ||
| MICROSCOPIC | 303 | ||
| DIFFERENTIAL DIAGNOSIS | 303 | ||
| DIAGNOSTIC CHECKLIST | 303 | ||
| SELECTED REFERENCES | 303 | ||
| Chapter 59. Prostatic-Type Polyp (Ectopic Prostate) | 306 | ||
| TERMINOLOGY | 307 | ||
| ETIOLOGY/PATHOGENESIS | 307 | ||
| CLINICAL ISSUES | 307 | ||
| MACROSCOPIC | 307 | ||
| MICROSCOPIC | 307 | ||
| ANCILLARY TESTS | 307 | ||
| DIFFERENTIAL DIAGNOSIS | 307 | ||
| DIAGNOSTIC CHECKLIST | 307 | ||
| SELECTED REFERENCES | 307 | ||
| Chapter 60. Amyloidosis | 312 | ||
| TERMINOLOGY | 313 | ||
| ETIOLOGY/PATHOGENESIS | 313 | ||
| CLINICAL ISSUES | 313 | ||
| MACROSCOPIC | 313 | ||
| MICROSCOPIC | 313 | ||
| ANCILLARY TESTS | 313 | ||
| DIFFERENTIAL DIAGNOSIS | 313 | ||
| DIAGNOSTIC CHECKLIST | 313 | ||
| SELECTED REFERENCES | 313 | ||
| Chapter 61. Müllerian Lesions | 314 | ||
| TERMINOLOGY | 315 | ||
| ETIOLOGY/PATHOGENESIS | 315 | ||
| CLINICAL ISSUES | 315 | ||
| IMAGING | 315 | ||
| MACROSCOPIC | 315 | ||
| MICROSCOPIC | 316 | ||
| ANCILLARY TESTS | 316 | ||
| DIFFERENTIAL DIAGNOSIS | 316 | ||
| DIAGNOSTIC CHECKLIST | 316 | ||
| SELECTED REFERENCES | 316 | ||
| Chapter 62. Pseudocarcinomatous Hyperplasia | 318 | ||
| TERMINOLOGY | 319 | ||
| ETIOLOGY/PATHOGENESIS | 319 | ||
| CLINICAL ISSUES | 319 | ||
| MACROSCOPIC | 319 | ||
| MICROSCOPIC | 319 | ||
| DIFFERENTIAL DIAGNOSIS | 320 | ||
| DIAGNOSTIC CHECKLIST | 320 | ||
| SELECTED REFERENCES | 320 | ||
| Chapter 63. Hamartoma | 326 | ||
| TERMINOLOGY | 327 | ||
| ETIOLOGY/PATHOGENESIS | 327 | ||
| CLINICAL ISSUES | 327 | ||
| IMAGING | 327 | ||
| MACROSCOPIC | 327 | ||
| MICROSCOPIC | 327 | ||
| ANCILLARY TESTS | 327 | ||
| DIFFERENTIAL DIAGNOSIS | 327 | ||
| DIAGNOSTIC CHECKLIST | 327 | ||
| SELECTED REFERENCES | 327 | ||
| Urothelial Neoplasms, General | 328 | ||
| Chapter 64. Overview of Urinary Bladder Neoplasms | 328 | ||
| EPIDEMIOLOGY | 328 | ||
| CLINICAL IMPLICATIONS | 329 | ||
| SELECTED REFERENCES | 330 | ||
| Flat Urothelial Lesions | 332 | ||
| Chapter 65. Urothelial Carcinoma In Situ | 332 | ||
| TERMINOLOGY | 333 | ||
| ETIOLOGY/PATHOGENESIS | 333 | ||
| CLINICAL ISSUES | 333 | ||
| MACROSCOPIC | 333 | ||
| MICROSCOPIC | 333 | ||
| ANCILLARY TESTS | 333 | ||
| DIFFERENTIAL DIAGNOSIS | 334 | ||
| DIAGNOSTIC CHECKLIST | 334 | ||
| SELECTED REFERENCES | 334 | ||
| Chapter 66. Flat Urothelial Lesions Other Than Carcinoma In Situ | 340 | ||
| TERMINOLOGY | 341 | ||
| CLINICAL ISSUES | 341 | ||
| MACROSCOPIC | 341 | ||
| MICROSCOPIC | 341 | ||
| DIFFERENTIAL DIAGNOSIS | 341 | ||
| DIAGNOSTIC CHECKLIST | 341 | ||
| SELECTED REFERENCES | 341 | ||
| Urothelial Neoplasms, Noninvasive | 344 | ||
| Chapter 67. Urothelial Papilloma | 344 | ||
| TERMINOLOGY | 345 | ||
| CLINICAL ISSUES | 345 | ||
| MACROSCOPIC | 345 | ||
| MICROSCOPIC | 345 | ||
| ANCILLARY TESTS | 345 | ||
| DIFFERENTIAL DIAGNOSIS | 345 | ||
| DIAGNOSTIC CHECKLIST | 345 | ||
| SELECTED REFERENCES | 345 | ||
| Chapter 68. Papillary Urothelial Neoplasm of Low Malignant Potential | 350 | ||
| TERMINOLOGY | 351 | ||
| CLINICAL ISSUES | 351 | ||
| MACROSCOPIC | 351 | ||
| MICROSCOPIC | 351 | ||
| DIFFERENTIAL DIAGNOSIS | 351 | ||
| DIAGNOSTIC CHECKLIST | 351 | ||
| SELECTED REFERENCES | 351 | ||
| Chapter 69. Low-Grade Papillary Urothelial Carcinoma | 354 | ||
| TERMINOLOGY | 355 | ||
| CLINICAL ISSUES | 355 | ||
| MACROSCOPIC | 355 | ||
| MICROSCOPIC | 355 | ||
| ANCILLARY TESTS | 355 | ||
| DIFFERENTIAL DIAGNOSIS | 355 | ||
| DIAGNOSTIC CHECKLIST | 355 | ||
| SELECTED REFERENCES | 355 | ||
| Chapter 70. High-Grade Papillary Urothelial Carcinoma | 358 | ||
| TERMINOLOGY | 359 | ||
| CLINICAL ISSUES | 359 | ||
| MACROSCOPIC | 359 | ||
| MICROSCOPIC | 359 | ||
| ANCILLARY TESTS | 359 | ||
| DIFFERENTIAL DIAGNOSIS | 359 | ||
| DIAGNOSTIC CHECKLIST | 359 | ||
| SELECTED REFERENCES | 359 | ||
| Chapter 71. Inverted Urothelial Neoplasia | 364 | ||
| TERMINOLOGY | 365 | ||
| CLINICAL ISSUES | 365 | ||
| MACROSCOPIC | 365 | ||
| MICROSCOPIC | 365 | ||
| DIFFERENTIAL DIAGNOSIS | 366 | ||
| DIAGNOSTIC CHECKLIST | 366 | ||
| SELECTED REFERENCES | 366 | ||
| Invasive Urothelial Carcinoma | 374 | ||
| Chapter 72. Invasive Urothelial Carcinoma | 374 | ||
| TERMINOLOGY | 375 | ||
| CLINICAL ISSUES | 375 | ||
| MACROSCOPIC | 375 | ||
| MICROSCOPIC | 375 | ||
| ANCILLARY TESTS | 375 | ||
| DIFFERENTIAL DIAGNOSIS | 375 | ||
| DIAGNOSTIC CHECKLIST | 376 | ||
| STAGING | 376 | ||
| REPORTING | 376 | ||
| SELECTED REFERENCES | 376 | ||
| Chapter 73. Overview of Invasive Carcinoma Subtypes | 382 | ||
| TERMINOLOGY | 382 | ||
| CLINICAL IMPLICATIONS | 382 | ||
| MACROSCOPIC | 382 | ||
| UC WITH ALTERNATIVE/ABERRANT DIFFERENTIATION | 382 | ||
| NESTED CARCINOMA | 382 | ||
| LARGE NESTED CARCINOMA | 383 | ||
| UC WITH SMALL TUBULES | 383 | ||
| MICROCYSTIC CARCINOMA | 383 | ||
| PLASMACYTOID CARCINOMA | 383 | ||
| MICROPAPILLARY CARCINOMA | 383 | ||
| LYMPHOEPITHELIOMA-LIKE CARCINOMA | 383 | ||
| SMALL CELL CARCINOMA | 384 | ||
| SARCOMATOID UC | 384 | ||
| UC WITH OSTEOCLAST-LIKE GIANT CELLS | 384 | ||
| UC WITH RHABDOID FEATURES | 384 | ||
| UC WITH MYXOID STROMA (INCLUDING CHORDOID) | 384 | ||
| UC WITH CLEAR CYTOPLASM (GLYCOGEN RICH) | 385 | ||
| UC WITH LIPOID FEATURES (LIPID RICH/LIPID CELL) | 385 | ||
| POORLY DIFFERENTIATED UROTHELIAL CARCINOMA | 385 | ||
| DIFFERENTIAL DIAGNOSIS | 385 | ||
| DIAGNOSTIC CHECKLIST | 385 | ||
| SELECTED REFERENCES | 385 | ||
| Glandular Lesions | 404 | ||
| Chapter 74. Cystitis Cystica and Glandularis | 404 | ||
| TERMINOLOGY | 405 | ||
| ETIOLOGY/PATHOGENESIS | 405 | ||
| CLINICAL ISSUES | 405 | ||
| MACROSCOPIC | 405 | ||
| MICROSCOPIC | 405 | ||
| DIFFERENTIAL DIAGNOSIS | 405 | ||
| DIAGNOSTIC CHECKLIST | 405 | ||
| SELECTED REFERENCES | 405 | ||
| Chapter 75. Villous Adenoma | 408 | ||
| TERMINOLOGY | 409 | ||
| CLINICAL ISSUES | 409 | ||
| MACROSCOPIC | 409 | ||
| MICROSCOPIC | 409 | ||
| ANCILLARY TESTS | 409 | ||
| DIFFERENTIAL DIAGNOSIS | 409 | ||
| DIAGNOSTIC CHECKLIST | 409 | ||
| SELECTED REFERENCES | 409 | ||
| Chapter 76. Invasive Adenocarcinoma | 410 | ||
| TERMINOLOGY | 411 | ||
| ETIOLOGY/PATHOGENESIS | 411 | ||
| CLINICAL ISSUES | 411 | ||
| MACROSCOPIC | 411 | ||
| MICROSCOPIC | 411 | ||
| ANCILLARY TESTS | 411 | ||
| DIFFERENTIAL DIAGNOSIS | 411 | ||
| DIAGNOSTIC CHECKLIST | 411 | ||
| SELECTED REFERENCES | 411 | ||
| Chapter 77. Clear Cell Adenocarcinoma | 416 | ||
| TERMINOLOGY | 417 | ||
| ETIOLOGY/PATHOGENESIS | 417 | ||
| CLINICAL ISSUES | 417 | ||
| MACROSCOPIC | 417 | ||
| MICROSCOPIC | 417 | ||
| ANCILLARY TESTS | 417 | ||
| DIFFERENTIAL DIAGNOSIS | 417 | ||
| DIAGNOSTIC CHECKLIST | 417 | ||
| SELECTED REFERENCES | 417 | ||
| Squamous Lesions | 422 | ||
| Chapter 78. Squamous Proliferations Other Than Carcinoma | 422 | ||
| TERMINOLOGY | 423 | ||
| ETIOLOGY/PATHOGENESIS | 423 | ||
| CLINICAL ISSUES | 423 | ||
| MICROSCOPIC | 423 | ||
| ANCILLARY TESTS | 423 | ||
| DIFFERENTIAL DIAGNOSIS | 423 | ||
| DIAGNOSTIC CHECKLIST | 423 | ||
| SELECTED REFERENCES | 423 | ||
| Chapter 79. Invasive Squamous Cell Carcinoma | 426 | ||
| TERMINOLOGY | 427 | ||
| ETIOLOGY/PATHOGENESIS | 427 | ||
| CLINICAL ISSUES | 427 | ||
| MACROSCOPIC | 427 | ||
| MICROSCOPIC | 427 | ||
| DIFFERENTIAL DIAGNOSIS | 427 | ||
| DIAGNOSTIC CHECKLIST | 427 | ||
| SELECTED REFERENCES | 427 | ||
| Mesenchymal Lesions | 432 | ||
| Chapter 80. Myofibroblastic Proliferations | 432 | ||
| TERMINOLOGY | 433 | ||
| ETIOLOGY/PATHOGENESIS | 433 | ||
| CLINICAL ISSUES | 433 | ||
| MACROSCOPIC | 433 | ||
| MICROSCOPIC | 433 | ||
| ANCILLARY TESTS | 433 | ||
| DIFFERENTIAL DIAGNOSIS | 433 | ||
| DIAGNOSTIC CHECKLIST | 434 | ||
| SELECTED REFERENCES | 434 | ||
| Chapter 81. Smooth Muscle Tumors | 440 | ||
| TERMINOLOGY | 441 | ||
| ETIOLOGY/PATHOGENESIS | 441 | ||
| CLINICAL ISSUES | 441 | ||
| MACROSCOPIC | 441 | ||
| MICROSCOPIC | 441 | ||
| ANCILLARY TESTS | 441 | ||
| DIFFERENTIAL DIAGNOSIS | 441 | ||
| DIAGNOSTIC CHECKLIST | 442 | ||
| SELECTED REFERENCES | 442 | ||
| Chapter 82. Skeletal Muscle Tumors | 448 | ||
| TERMINOLOGY | 449 | ||
| CLINICAL ISSUES | 449 | ||
| MACROSCOPIC | 449 | ||
| MICROSCOPIC | 449 | ||
| ANCILLARY TESTS | 449 | ||
| DIFFERENTIAL DIAGNOSIS | 449 | ||
| DIAGNOSTIC CHECKLIST | 449 | ||
| SELECTED REFERENCES | 449 | ||
| Chapter 83. Other Mesenchymal Tumors | 454 | ||
| TERMINOLOGY | 455 | ||
| CLINICAL ISSUES | 455 | ||
| MICROSCOPIC | 455 | ||
| DIFFERENTIAL DIAGNOSIS | 456 | ||
| SELECTED REFERENCES | 456 | ||
| Other Tumors of Urinary Bladder | 462 | ||
| Chapter 84. Paraganglioma | 462 | ||
| TERMINOLOGY | 463 | ||
| ETIOLOGY/PATHOGENESIS | 463 | ||
| CLINICAL ISSUES | 463 | ||
| MACROSCOPIC | 463 | ||
| MICROSCOPIC | 463 | ||
| ANCILLARY TESTS | 463 | ||
| DIFFERENTIAL DIAGNOSIS | 464 | ||
| DIAGNOSTIC CHECKLIST | 464 | ||
| SELECTED REFERENCES | 464 | ||
| Chapter 85. Metastatic and Secondary Carcinomas | 470 | ||
| TERMINOLOGY | 471 | ||
| CLINICAL ISSUES | 471 | ||
| MACROSCOPIC | 471 | ||
| MICROSCOPIC | 471 | ||
| ANCILLARY TESTS | 471 | ||
| DIFFERENTIAL DIAGNOSIS | 471 | ||
| DIAGNOSTIC CHECKLIST | 472 | ||
| SELECTED REFERENCES | 472 | ||
| Diverticula of Urinary Tract | 478 | ||
| Chapter 86. Diverticula | 478 | ||
| TERMINOLOGY | 479 | ||
| ETIOLOGY/PATHOGENESIS | 479 | ||
| CLINICAL ISSUES | 479 | ||
| IMAGING | 479 | ||
| MACROSCOPIC | 479 | ||
| MICROSCOPIC | 479 | ||
| SELECTED REFERENCES | 479 | ||
| Chapter 87. Diverticular-Associated Neoplasia | 482 | ||
| TERMINOLOGY | 483 | ||
| CLINICAL ISSUES | 483 | ||
| MACROSCOPIC | 483 | ||
| MICROSCOPIC | 483 | ||
| SELECTED REFERENCES | 483 | ||
| Urethra | 486 | ||
| Chapter 88. Inflammatory Lesions of Urethra | 486 | ||
| TERMINOLOGY | 487 | ||
| ETIOLOGY/PATHOGENESIS | 487 | ||
| CLINICAL ISSUES | 487 | ||
| MICROSCOPIC | 488 | ||
| DIFFERENTIAL DIAGNOSIS | 488 | ||
| SELECTED REFERENCES | 488 | ||
| Chapter 89. Carcinoma of Urethra | 490 | ||
| TERMINOLOGY | 491 | ||
| CLINICAL ISSUES | 491 | ||
| MACROSCOPIC | 492 | ||
| MICROSCOPIC | 492 | ||
| DIFFERENTIAL DIAGNOSIS | 492 | ||
| SELECTED REFERENCES | 492 | ||
| Chapter 90. Other Tumors and Tumor-Like Lesions of Urethra | 494 | ||
| TERMINOLOGY | 495 | ||
| ETIOLOGY/PATHOGENESIS | 495 | ||
| CLINICAL ISSUES | 495 | ||
| MICROSCOPIC | 495 | ||
| DIFFERENTIAL DIAGNOSIS | 496 | ||
| SELECTED REFERENCES | 496 | ||
| Ureter | 498 | ||
| Chapter 91. Urothelial Carcinoma of Ureter | 498 | ||
| TERMINOLOGY | 499 | ||
| ETIOLOGY/PATHOGENESIS | 499 | ||
| CLINICAL ISSUES | 499 | ||
| IMAGING | 499 | ||
| MACROSCOPIC | 500 | ||
| MICROSCOPIC | 500 | ||
| ANCILLARY TESTS | 500 | ||
| DIFFERENTIAL DIAGNOSIS | 500 | ||
| SELECTED REFERENCES | 500 | ||
| Chapter 92. Other Tumors and Tumor-Like Lesions of Ureter | 502 | ||
| TERMINOLOGY | 503 | ||
| ETIOLOGY/PATHOGENESIS | 503 | ||
| CLINICAL ISSUES | 503 | ||
| MACROSCOPIC | 503 | ||
| MICROSCOPIC | 503 | ||
| ANCILLARY TESTS | 504 | ||
| DIFFERENTIAL DIAGNOSIS | 504 | ||
| DIAGNOSTIC CHECKLIST | 504 | ||
| SELECTED REFERENCES | 504 | ||
| Renal Pelvis | 506 | ||
| Chapter 93. Urothelial Carcinoma of Renal Pelvis | 506 | ||
| TERMINOLOGY | 507 | ||
| ETIOLOGY/PATHOGENESIS | 507 | ||
| CLINICAL ISSUES | 507 | ||
| IMAGING | 507 | ||
| MACROSCOPIC | 507 | ||
| MICROSCOPIC | 508 | ||
| ANCILLARY TESTS | 508 | ||
| DIFFERENTIAL DIAGNOSIS | 508 | ||
| DIAGNOSTIC CHECKLIST | 508 | ||
| SELECTED REFERENCES | 508 | ||
| Chapter 94. Other Tumors and Tumor-Like Lesions of Renal Pelvis | 514 | ||
| TERMINOLOGY | 515 | ||
| ETIOLOGY/PATHOGENESIS | 515 | ||
| CLINICAL ISSUES | 515 | ||
| MACROSCOPIC | 515 | ||
| MICROSCOPIC | 515 | ||
| DIFFERENTIAL DIAGNOSIS | 516 | ||
| DIAGNOSTIC CHECKLIST | 516 | ||
| SELECTED REFERENCES | 516 | ||
| Urachus | 520 | ||
| Chapter 95. Urachal Remnants | 520 | ||
| TERMINOLOGY | 521 | ||
| ETIOLOGY/PATHOGENESIS | 521 | ||
| CLINICAL ISSUES | 521 | ||
| MICROSCOPIC | 521 | ||
| DIFFERENTIAL DIAGNOSIS | 521 | ||
| SELECTED REFERENCES | 521 | ||
| Chapter 96. Tumors of Urachus | 522 | ||
| TERMINOLOGY | 523 | ||
| CLASSIFICATION | 523 | ||
| ETIOLOGY/PATHOGENESIS | 523 | ||
| CLINICAL ISSUES | 523 | ||
| IMAGING | 523 | ||
| MACROSCOPIC | 524 | ||
| MICROSCOPIC | 524 | ||
| ANCILLARY TESTS | 524 | ||
| DIFFERENTIAL DIAGNOSIS | 524 | ||
| REPORTING | 524 | ||
| SELECTED REFERENCES | 524 | ||
| Immunohistochemistry, Urinary Tract | 528 | ||
| Chapter 97. Immunohistochemistry, Urinary Tract | 528 | ||
| SECTION 3:\rProstate Gland and Seminal Vesicle | 534 | ||
| Introduction and Overview | 536 | ||
| Chapter 98. Classification of Prostate Tumors and Tumor-Like Lesions | 536 | ||
| NONNEOPLASTIC LESIONS | 536 | ||
| NEOPLASMS | 536 | ||
| Chapter 99. General Concepts, Prostate | 538 | ||
| ANATOMIC FEATURES | 538 | ||
| SPECIMEN TYPES AND HANDLING | 539 | ||
| IMMUNOHISTOCHEMISTRY | 541 | ||
| SELECTED REFERENCES | 541 | ||
| Chapter 100. Microanatomy and Zonal Variations | 544 | ||
| DUCTAL ACINAR UNIT | 544 | ||
| PROSTATE ANATOMIC ZONES | 545 | ||
| ZONAL VARIATIONS IN HISTOLOGY | 545 | ||
| LUMINAL AND CELLULAR DEPOSITS | 545 | ||
| NONGLANDULAR PROSTATE | 546 | ||
| NONPROSTATIC STRUCTURES | 546 | ||
| PERIPROSTATIC STRUCTURES | 546 | ||
| SEMINAL VESICLE | 547 | ||
| SELECTED REFERENCES | 547 | ||
| Prostatitis | 554 | ||
| Chapter 101. Prostatitis | 554 | ||
| TERMINOLOGY | 555 | ||
| ETIOLOGY/PATHOGENESIS | 555 | ||
| CLINICAL ISSUES | 555 | ||
| MICROSCOPIC | 556 | ||
| DIFFERENTIAL DIAGNOSIS | 556 | ||
| DIAGNOSTIC CHECKLIST | 556 | ||
| SELECTED REFERENCES | 556 | ||
| Chapter 102. Prostate Hyperplasia | 558 | ||
| TERMINOLOGY | 559 | ||
| ETIOLOGY/PATHOGENESIS | 559 | ||
| CLINICAL ISSUES | 559 | ||
| IMAGING | 559 | ||
| MACROSCOPIC | 559 | ||
| MICROSCOPIC | 559 | ||
| ANCILLARY TESTS | 560 | ||
| DIFFERENTIAL DIAGNOSIS | 560 | ||
| SELECTED REFERENCES | 560 | ||
| Chapter 103. Adenosis | 566 | ||
| TERMINOLOGY | 567 | ||
| CLINICAL ISSUES | 567 | ||
| MICROSCOPIC | 567 | ||
| ANCILLARY TESTS | 567 | ||
| DIFFERENTIAL DIAGNOSIS | 567 | ||
| DIAGNOSTIC CHECKLIST | 567 | ||
| REPORTING | 567 | ||
| SELECTED REFERENCES | 567 | ||
| Chapter 104. Atrophy and Its Variants | 570 | ||
| TERMINOLOGY | 571 | ||
| ETIOLOGY/PATHOGENESIS | 571 | ||
| CLINICAL ISSUES | 571 | ||
| MICROSCOPIC | 571 | ||
| ANCILLARY TESTS | 571 | ||
| DIFFERENTIAL DIAGNOSIS | 571 | ||
| SELECTED REFERENCES | 571 | ||
| Chapter 105. Hyperplasia of Mesonephric Remnants | 576 | ||
| TERMINOLOGY | 577 | ||
| ETIOLOGY/PATHOGENESIS | 577 | ||
| CLINICAL ISSUES | 577 | ||
| MACROSCOPIC | 577 | ||
| MICROSCOPIC | 577 | ||
| ANCILLARY TESTS | 577 | ||
| DIFFERENTIAL DIAGNOSIS | 577 | ||
| SELECTED REFERENCES | 577 | ||
| Chapter 106. Verumontanum Mucosal Gland Hyperplasia | 580 | ||
| TERMINOLOGY | 581 | ||
| ETIOLOGY/PATHOGENESIS | 581 | ||
| CLINICAL ISSUES | 581 | ||
| MICROSCOPIC | 581 | ||
| DIFFERENTIAL DIAGNOSIS | 581 | ||
| DIAGNOSTIC CHECKLIST | 581 | ||
| SELECTED REFERENCES | 581 | ||
| Chapter 107. Nephrogenic Adenoma (Metaplasia) of Prostatic Urethra | 582 | ||
| TERMINOLOGY | 583 | ||
| ETIOLOGY/PATHOGENESIS | 583 | ||
| CLINICAL ISSUES | 583 | ||
| MACROSCOPIC | 583 | ||
| MICROSCOPIC | 583 | ||
| ANCILLARY TESTS | 584 | ||
| DIFFERENTIAL DIAGNOSIS | 584 | ||
| DIAGNOSTIC CHECKLIST | 584 | ||
| SELECTED REFERENCES | 584 | ||
| Putative Premalignant Lesions and\rLesions Falling Short of Malignant Diagnosis | 590 | ||
| Chapter 108. Prostatic Intraepithelial Neoplasia | 590 | ||
| TERMINOLOGY | 591 | ||
| ETIOLOGY/PATHOGENESIS | 591 | ||
| CLINICAL ISSUES | 591 | ||
| IMAGING | 591 | ||
| MACROSCOPIC | 591 | ||
| MICROSCOPIC | 591 | ||
| ANCILLARY TESTS | 592 | ||
| DIFFERENTIAL DIAGNOSIS | 592 | ||
| DIAGNOSTIC CHECKLIST | 593 | ||
| REPORTING | 593 | ||
| SELECTED REFERENCES | 593 | ||
| Prostate Neoplasms | 600 | ||
| Chapter 109. General Concepts, Prostate Carcinoma | 600 | ||
| TERMINOLOGY | 600 | ||
| EPIDEMIOLOGY | 600 | ||
| ETIOLOGY/PATHOGENESIS | 600 | ||
| CLINICAL IMPLICATIONS | 601 | ||
| RISK ASSESSMENT AND TREATMENT\rOPTIONS | 602 | ||
| KEY FEATURES IN EXAMINATION OF\rPROSTATE CANCER SPECIMENS | 603 | ||
| STAGING | 604 | ||
| SELECTED REFERENCES | 604 | ||
| Chapter 110. Acinar Adenocarcinoma | 608 | ||
| TERMINOLOGY | 609 | ||
| ETIOLOGY/PATHOGENESIS | 609 | ||
| MACROSCOPIC | 609 | ||
| MICROSCOPIC | 609 | ||
| DIFFERENTIAL DIAGNOSIS | 611 | ||
| SELECTED REFERENCES | 611 | ||
| Chapter 111. Acinar Adenocarcinoma Variants | 626 | ||
| TERMINOLOGY | 627 | ||
| CLINICAL ISSUES | 627 | ||
| DIAGNOSTIC CHECKLIST | 627 | ||
| SELECTED REFERENCES | 629 | ||
| Chapter 112. Atypical Small Acinar Proliferations | 638 | ||
| TERMINOLOGY | 639 | ||
| CLINICAL ISSUES | 639 | ||
| MACROSCOPIC | 639 | ||
| MICROSCOPIC | 639 | ||
| ANCILLARY TESTS | 640 | ||
| DIFFERENTIAL DIAGNOSIS | 640 | ||
| DIAGNOSTIC CHECKLIST | 641 | ||
| REPORTING | 641 | ||
| SELECTED REFERENCES | 641 | ||
| Chapter 113. Intraductal Carcinoma | 644 | ||
| TERMINOLOGY | 645 | ||
| ETIOLOGY/PATHOGENESIS | 645 | ||
| CLINICAL ISSUES | 645 | ||
| MACROSCOPIC | 645 | ||
| MICROSCOPIC | 645 | ||
| ANCILLARY TESTS | 646 | ||
| DIFFERENTIAL DIAGNOSIS | 646 | ||
| DIAGNOSTIC CHECKLIST | 646 | ||
| REPORTING | 646 | ||
| SELECTED REFERENCES | 646 | ||
| Chapter 114. Ductal Adenocarcinoma | 650 | ||
| TERMINOLOGY | 651 | ||
| ETIOLOGY/PATHOGENESIS | 651 | ||
| CLINICAL ISSUES | 651 | ||
| MACROSCOPIC | 651 | ||
| MICROSCOPIC | 651 | ||
| ANCILLARY TESTS | 652 | ||
| DIFFERENTIAL DIAGNOSIS | 652 | ||
| DIAGNOSTIC CHECKLIST | 652 | ||
| GRADING | 652 | ||
| SELECTED REFERENCES | 652 | ||
| Chapter 115. Urothelial Carcinoma Involving Prostate Gland | 658 | ||
| TERMINOLOGY | 659 | ||
| CLASSIFICATION | 659 | ||
| CLINICAL ISSUES | 659 | ||
| IMAGING | 660 | ||
| MACROSCOPIC | 660 | ||
| MICROSCOPIC | 660 | ||
| STAGING | 661 | ||
| SELECTED REFERENCES | 661 | ||
| Chapter 116. Prostate Carcinoma With Neuroendocrine Differentiation | 664 | ||
| TERMINOLOGY | 665 | ||
| CLASSIFICATION | 665 | ||
| ETIOLOGY/PATHOGENESIS | 665 | ||
| CLINICAL ISSUES | 665 | ||
| MOLECULAR | 666 | ||
| MICROSCOPIC | 666 | ||
| ANCILLARY TESTS | 667 | ||
| DIFFERENTIAL DIAGNOSIS | 667 | ||
| REPORTING | 667 | ||
| SELECTED REFERENCES | 667 | ||
| Chapter 117. Basal Cell Carcinoma | 672 | ||
| TERMINOLOGY | 673 | ||
| ETIOLOGY/PATHOGENESIS | 673 | ||
| CLINICAL ISSUES | 673 | ||
| MACROSCOPIC | 673 | ||
| MICROSCOPIC | 673 | ||
| ANCILLARY TESTS | 673 | ||
| DIFFERENTIAL DIAGNOSIS | 674 | ||
| DIAGNOSTIC CHECKLIST | 674 | ||
| GRADING | 674 | ||
| STAGING | 674 | ||
| SELECTED REFERENCES | 674 | ||
| Chapter 118. Sarcomatoid Carcinoma of Prostate | 678 | ||
| TERMINOLOGY | 679 | ||
| ETIOLOGY/PATHOGENESIS | 679 | ||
| CLINICAL ISSUES | 679 | ||
| MACROSCOPIC | 679 | ||
| MICROSCOPIC | 679 | ||
| ANCILLARY TESTS | 680 | ||
| DIFFERENTIAL DIAGNOSIS | 680 | ||
| DIAGNOSTIC CHECKLIST | 680 | ||
| SELECTED REFERENCES | 680 | ||
| Chapter 119. Carcinomas With Squamous Differentiation | 684 | ||
| TERMINOLOGY | 685 | ||
| ETIOLOGY/PATHOGENESIS | 685 | ||
| CLINICAL ISSUES | 685 | ||
| MACROSCOPIC | 685 | ||
| MICROSCOPIC | 685 | ||
| ANCILLARY TESTS | 686 | ||
| DIFFERENTIAL DIAGNOSIS | 686 | ||
| DIAGNOSTIC CHECKLIST | 686 | ||
| GRADING | 686 | ||
| REPORTING | 686 | ||
| SELECTED REFERENCES | 686 | ||
| Chapter 120. Stromal Tumors | 690 | ||
| TERMINOLOGY | 691 | ||
| ETIOLOGY/PATHOGENESIS | 691 | ||
| CLINICAL ISSUES | 691 | ||
| MACROSCOPIC | 692 | ||
| MICROSCOPIC | 692 | ||
| DIFFERENTIAL DIAGNOSIS | 693 | ||
| DIAGNOSTIC CHECKLIST | 693 | ||
| SELECTED REFERENCES | 693 | ||
| Chapter 121. Mesenchymal Tumors of Prostate | 698 | ||
| TERMINOLOGY | 699 | ||
| CLINICAL ISSUES | 699 | ||
| DIAGNOSTIC CHECKLIST | 699 | ||
| SELECTED REFERENCES | 702 | ||
| Chapter 122. Melanocytic Lesions of Prostate | 706 | ||
| TERMINOLOGY | 707 | ||
| ETIOLOGY/PATHOGENESIS | 707 | ||
| CLINICAL ISSUES | 707 | ||
| MACROSCOPIC | 707 | ||
| MICROSCOPIC | 707 | ||
| ANCILLARY TESTS | 707 | ||
| DIFFERENTIAL DIAGNOSIS | 707 | ||
| SELECTED REFERENCES | 707 | ||
| Chapter 123. Hematopoietic Neoplasms of Prostate | 710 | ||
| TERMINOLOGY | 711 | ||
| CLINICAL ISSUES | 711 | ||
| MICROSCOPIC | 711 | ||
| ANCILLARY TESTS | 711 | ||
| DIFFERENTIAL DIAGNOSIS | 711 | ||
| SELECTED REFERENCES | 711 | ||
| Chapter 124. Secondary Tumors of Prostate | 714 | ||
| TERMINOLOGY | 715 | ||
| ETIOLOGY/PATHOGENESIS | 715 | ||
| CLINICAL ISSUES | 715 | ||
| IMAGING | 715 | ||
| MICROSCOPIC | 715 | ||
| ANCILLARY TESTS | 715 | ||
| SELECTED REFERENCES | 715 | ||
| Tumors of Seminal Vesicle | 718 | ||
| Chapter 125. Cystadenoma and Epithelial Stromal Tumor | 718 | ||
| TERMINOLOGY | 719 | ||
| ETIOLOGY/PATHOGENESIS | 719 | ||
| CLINICAL ISSUES | 719 | ||
| IMAGING | 719 | ||
| MACROSCOPIC | 719 | ||
| MICROSCOPIC | 719 | ||
| ANCILLARY TESTS | 720 | ||
| DIFFERENTIAL DIAGNOSIS | 720 | ||
| DIAGNOSTIC CHECKLIST | 720 | ||
| SELECTED REFERENCES | 720 | ||
| Chapter 126. Seminal Vesicle Adenocarcinoma | 722 | ||
| TERMINOLOGY | 723 | ||
| CLINICAL ISSUES | 723 | ||
| IMAGING | 723 | ||
| MACROSCOPIC | 723 | ||
| MICROSCOPIC | 723 | ||
| ANCILLARY TESTS | 723 | ||
| DIFFERENTIAL DIAGNOSIS | 723 | ||
| SELECTED REFERENCES | 723 | ||
| Immunohistochemical Profiles for Tumors and Tumor-Like Lesions Involving Prostate Gland | 724 | ||
| Chapter 127. Immunohistochemistry, Prostate | 724 | ||
| SECTION 4:\rTestis and Paratesticular Structures | 730 | ||
| Introduction and Overview | 732 | ||
| Chapter 128. Classification of Testis and Paratestis Tumors and Tumor-Like Lesions | 732 | ||
| NONNEOPLASTIC LESIONS | 732 | ||
| NEOPLASMS | 732 | ||
| Nonneoplastic Lesions | 734 | ||
| Chapter 129. Cryptorchidism | 734 | ||
| TERMINOLOGY | 735 | ||
| ETIOLOGY/PATHOGENESIS | 735 | ||
| CLINICAL ISSUES | 735 | ||
| IMAGING | 735 | ||
| MACROSCOPIC | 735 | ||
| MICROSCOPIC | 735 | ||
| DIAGNOSTIC CHECKLIST | 735 | ||
| SELECTED REFERENCES | 735 | ||
| Chapter 130. Sertoli Cell-Only Syndrome | 738 | ||
| TERMINOLOGY | 739 | ||
| ETIOLOGY/PATHOGENESIS | 739 | ||
| CLINICAL ISSUES | 739 | ||
| MACROSCOPIC | 739 | ||
| MICROSCOPIC | 739 | ||
| DIFFERENTIAL DIAGNOSIS | 739 | ||
| SELECTED REFERENCES | 739 | ||
| Chapter 131. Nontuberculous Infections | 742 | ||
| TERMINOLOGY | 743 | ||
| ETIOLOGY/PATHOGENESIS | 743 | ||
| CLINICAL ISSUES | 743 | ||
| MACROSCOPIC | 743 | ||
| MICROSCOPIC | 743 | ||
| DIFFERENTIAL DIAGNOSIS | 743 | ||
| SELECTED REFERENCES | 743 | ||
| Chapter 132. Nonspecific Granulomatous Orchitis | 744 | ||
| TERMINOLOGY | 745 | ||
| ETIOLOGY/PATHOGENESIS | 745 | ||
| CLINICAL ISSUES | 745 | ||
| MACROSCOPIC | 745 | ||
| MICROSCOPIC | 745 | ||
| ANCILLARY TESTS | 745 | ||
| DIFFERENTIAL DIAGNOSIS | 745 | ||
| SELECTED REFERENCES | 745 | ||
| Chapter 133. Tuberculous Epididymo-Orchitis | 746 | ||
| TERMINOLOGY | 747 | ||
| ETIOLOGY/PATHOGENESIS | 747 | ||
| CLINICAL ISSUES | 747 | ||
| IMAGING | 747 | ||
| MACROSCOPIC | 747 | ||
| MICROSCOPIC | 747 | ||
| ANCILLARY TESTS | 747 | ||
| DIFFERENTIAL DIAGNOSIS | 747 | ||
| SELECTED REFERENCES | 747 | ||
| Germ Cell Tumors | 748 | ||
| Chapter 134. General Concepts, Germ Cell Tumors | 748 | ||
| TERMINOLOGY | 748 | ||
| EPIDEMIOLOGY | 748 | ||
| ETIOLOGY/PATHOGENESIS | 748 | ||
| CLINICAL IMPLICATIONS | 748 | ||
| MACROSCOPIC | 749 | ||
| MICROSCOPIC | 749 | ||
| IMMUNOHISTOCHEMISTRY | 750 | ||
| REPORTING CRITERIA | 751 | ||
| TNM TUMOR STAGING | 751 | ||
| SELECTED REFERENCES | 752 | ||
| Germ Cell Tumors Related to Germ\rCell Neoplasia In Situ | 756 | ||
| Chapter 135. Germ Cell Neoplasia In Situ | 756 | ||
| TERMINOLOGY | 757 | ||
| CLINICAL ISSUES | 757 | ||
| IMAGING | 757 | ||
| MACROSCOPIC | 757 | ||
| MICROSCOPIC | 757 | ||
| ANCILLARY TESTS | 757 | ||
| DIFFERENTIAL DIAGNOSIS | 757 | ||
| SELECTED REFERENCES | 757 | ||
| Chapter 136. Seminoma | 762 | ||
| TERMINOLOGY | 763 | ||
| CLINICAL ISSUES | 763 | ||
| MACROSCOPIC | 763 | ||
| MICROSCOPIC | 763 | ||
| ANCILLARY TESTS | 764 | ||
| DIFFERENTIAL DIAGNOSIS | 764 | ||
| DIAGNOSTIC CHECKLIST | 764 | ||
| REPORTING | 764 | ||
| SELECTED REFERENCES | 764 | ||
| Chapter 137. Embryonal Carcinoma | 770 | ||
| TERMINOLOGY | 771 | ||
| CLINICAL ISSUES | 771 | ||
| IMAGING | 771 | ||
| MACROSCOPIC | 771 | ||
| MICROSCOPIC | 771 | ||
| ANCILLARY TESTS | 771 | ||
| DIFFERENTIAL DIAGNOSIS | 771 | ||
| DIAGNOSTIC CHECKLIST | 772 | ||
| REPORTING | 772 | ||
| SELECTED REFERENCES | 772 | ||
| Chapter 138. Yolk Sac Tumor | 776 | ||
| TERMINOLOGY | 777 | ||
| CLINICAL ISSUES | 777 | ||
| IMAGING | 777 | ||
| MACROSCOPIC | 777 | ||
| MICROSCOPIC | 777 | ||
| ANCILLARY TESTS | 778 | ||
| DIFFERENTIAL DIAGNOSIS | 778 | ||
| DIAGNOSTIC CHECKLIST | 778 | ||
| REPORTING | 778 | ||
| SELECTED REFERENCES | 778 | ||
| Chapter 139. Choriocarcinoma and Variants | 784 | ||
| TERMINOLOGY | 785 | ||
| CLINICAL ISSUES | 785 | ||
| IMAGING | 785 | ||
| MACROSCOPIC | 785 | ||
| MICROSCOPIC | 785 | ||
| ANCILLARY TESTS | 786 | ||
| DIFFERENTIAL DIAGNOSIS | 786 | ||
| DIAGNOSTIC CHECKLIST | 786 | ||
| REPORTING | 786 | ||
| SELECTED REFERENCES | 786 | ||
| Chapter 140. Teratoma, Adult Type | 790 | ||
| TERMINOLOGY | 791 | ||
| ETIOLOGY/PATHOGENESIS | 791 | ||
| CLINICAL ISSUES | 791 | ||
| IMAGING | 791 | ||
| MACROSCOPIC | 791 | ||
| MICROSCOPIC | 791 | ||
| ANCILLARY TESTS | 791 | ||
| DIFFERENTIAL DIAGNOSIS | 791 | ||
| SELECTED REFERENCES | 791 | ||
| Chapter 141. Mixed Germ Cell Tumors | 794 | ||
| TERMINOLOGY | 795 | ||
| CLINICAL ISSUES | 795 | ||
| IMAGING | 795 | ||
| MACROSCOPIC | 795 | ||
| MICROSCOPIC | 795 | ||
| ANCILLARY TESTS | 795 | ||
| DIFFERENTIAL DIAGNOSIS | 795 | ||
| REPORTING | 795 | ||
| SELECTED REFERENCES | 795 | ||
| Chapter 142. Somatic-Type Malignancy in Germ Cell Tumor | 798 | ||
| TERMINOLOGY | 799 | ||
| CLINICAL ISSUES | 799 | ||
| IMAGING | 799 | ||
| MACROSCOPIC | 799 | ||
| MICROSCOPIC | 799 | ||
| ANCILLARY TESTS | 799 | ||
| DIFFERENTIAL DIAGNOSIS | 799 | ||
| DIAGNOSTIC CHECKLIST | 799 | ||
| SELECTED REFERENCES | 799 | ||
| Chapter 143. Burnt-Out (Regressed) Germ Cell Tumor | 800 | ||
| TERMINOLOGY | 801 | ||
| CLINICAL ISSUES | 801 | ||
| IMAGING | 801 | ||
| MACROSCOPIC | 801 | ||
| MICROSCOPIC | 801 | ||
| ANCILLARY TESTS | 801 | ||
| DIFFERENTIAL DIAGNOSIS | 801 | ||
| DIAGNOSTIC CHECKLIST | 801 | ||
| SELECTED REFERENCES | 801 | ||
| Germ Cell Tumors Unrelated to Germ Cell Neoplasia In Situ | 802 | ||
| Chapter 144. Spermatocytic Tumor | 802 | ||
| TERMINOLOGY | 803 | ||
| ETIOLOGY/PATHOGENESIS | 803 | ||
| CLINICAL ISSUES | 803 | ||
| MACROSCOPIC | 803 | ||
| MICROSCOPIC | 803 | ||
| ANCILLARY TESTS | 803 | ||
| DIFFERENTIAL DIAGNOSIS | 803 | ||
| SELECTED REFERENCES | 803 | ||
| Chapter 145. Teratoma, Prepubertal Type | 806 | ||
| TERMINOLOGY | 807 | ||
| ETIOLOGY/PATHOGENESIS | 807 | ||
| CLINICAL ISSUES | 807 | ||
| IMAGING | 807 | ||
| MACROSCOPIC | 807 | ||
| MICROSCOPIC | 807 | ||
| DIFFERENTIAL DIAGNOSIS | 807 | ||
| DIAGNOSTIC CHECKLIST | 807 | ||
| SELECTED REFERENCES | 807 | ||
| Chapter 146. Yolk Sac Tumor, Prepubertal Type | 810 | ||
| TERMINOLOGY | 811 | ||
| ETIOLOGY/PATHOGENESIS | 811 | ||
| CLINICAL ISSUES | 811 | ||
| IMAGING | 811 | ||
| MACROSCOPIC | 811 | ||
| MICROSCOPIC | 811 | ||
| ANCILLARY TESTS | 811 | ||
| DIFFERENTIAL DIAGNOSIS | 811 | ||
| DIAGNOSTIC CHECKLIST | 811 | ||
| SELECTED REFERENCES | 811 | ||
| Chapter 147. Carcinoid Tumor | 814 | ||
| TERMINOLOGY | 815 | ||
| ETIOLOGY/PATHOGENESIS | 815 | ||
| CLINICAL ISSUES | 815 | ||
| IMAGING | 815 | ||
| MACROSCOPIC | 815 | ||
| MICROSCOPIC | 815 | ||
| ANCILLARY TESTS | 815 | ||
| DIFFERENTIAL DIAGNOSIS | 815 | ||
| SELECTED REFERENCES | 815 | ||
| Sex Cord-/Gonadal Stromal Tumors | 818 | ||
| Chapter 148. General Concepts, Sex Cord-/Gonadal Stromal Tumors | 818 | ||
| TERMINOLOGY | 818 | ||
| EPIDEMIOLOGY | 818 | ||
| ETIOLOGY/PATHOGENESIS | 818 | ||
| CLINICAL IMPLICATIONS | 818 | ||
| MACROSCOPIC | 818 | ||
| MICROSCOPIC | 819 | ||
| IMMUNOHISTOCHEMISTRY | 819 | ||
| DIFFERENTIAL DIAGNOSIS | 820 | ||
| SELECTED REFERENCES | 820 | ||
| Chapter 149. Leydig Cell Tumors | 824 | ||
| TERMINOLOGY | 825 | ||
| CLINICAL ISSUES | 825 | ||
| MACROSCOPIC | 825 | ||
| MICROSCOPIC | 825 | ||
| ANCILLARY TESTS | 825 | ||
| DIFFERENTIAL DIAGNOSIS | 825 | ||
| SELECTED REFERENCES | 825 | ||
| Chapter 150. Sertoli Cell Tumors | 828 | ||
| TERMINOLOGY | 829 | ||
| CLINICAL ISSUES | 829 | ||
| MACROSCOPIC | 829 | ||
| MICROSCOPIC | 829 | ||
| ANCILLARY TESTS | 829 | ||
| DIFFERENTIAL DIAGNOSIS | 829 | ||
| SELECTED REFERENCES | 829 | ||
| Chapter 151. Large Cell Calcifying Sertoli Cell Tumor | 834 | ||
| TERMINOLOGY | 835 | ||
| CLINICAL ISSUES | 835 | ||
| MACROSCOPIC | 835 | ||
| MICROSCOPIC | 835 | ||
| ANCILLARY TESTS | 835 | ||
| DIFFERENTIAL DIAGNOSIS | 835 | ||
| SELECTED REFERENCES | 835 | ||
| Chapter 152. Granulosa Cell Tumor | 838 | ||
| TERMINOLOGY | 839 | ||
| CLINICAL ISSUES | 839 | ||
| MACROSCOPIC | 839 | ||
| MICROSCOPIC | 839 | ||
| ANCILLARY TESTS | 839 | ||
| DIFFERENTIAL DIAGNOSIS | 839 | ||
| DIAGNOSTIC CHECKLIST | 839 | ||
| SELECTED REFERENCES | 839 | ||
| Chapter 153. Juvenile Granulosa Cell Tumor | 842 | ||
| TERMINOLOGY | 843 | ||
| CLINICAL ISSUES | 843 | ||
| MACROSCOPIC | 843 | ||
| MICROSCOPIC | 843 | ||
| ANCILLARY TESTS | 843 | ||
| DIFFERENTIAL DIAGNOSIS | 843 | ||
| SELECTED REFERENCES | 843 | ||
| Chapter 154. Testicular Tumor of Adrenogenital Syndrome | 846 | ||
| TERMINOLOGY | 847 | ||
| ETIOLOGY/PATHOGENESIS | 847 | ||
| CLINICAL ISSUES | 847 | ||
| MACROSCOPIC | 847 | ||
| MICROSCOPIC | 847 | ||
| ANCILLARY TESTS | 847 | ||
| DIFFERENTIAL DIAGNOSIS | 847 | ||
| SELECTED REFERENCES | 847 | ||
| Chapter 155. Sex Cord-Stromal Tumor, Mixed/Unclassified | 850 | ||
| TERMINOLOGY | 851 | ||
| CLINICAL ISSUES | 851 | ||
| MACROSCOPIC | 851 | ||
| MICROSCOPIC | 851 | ||
| ANCILLARY TESTS | 851 | ||
| DIFFERENTIAL DIAGNOSIS | 851 | ||
| DIAGNOSTIC CHECKLIST | 851 | ||
| SELECTED REFERENCES | 851 | ||
| Chapter 156. Gonadoblastoma | 854 | ||
| TERMINOLOGY | 855 | ||
| CLINICAL ISSUES | 855 | ||
| MACROSCOPIC | 855 | ||
| MICROSCOPIC | 855 | ||
| ANCILLARY TESTS | 855 | ||
| DIFFERENTIAL DIAGNOSIS | 855 | ||
| DIAGNOSTIC CHECKLIST | 855 | ||
| SELECTED REFERENCES | 855 | ||
| Hematopoietic Tumors | 858 | ||
| Chapter 157. Lymphoma/Leukemia/Plasmacytoma | 858 | ||
| TERMINOLOGY | 859 | ||
| CLINICAL ISSUES | 859 | ||
| IMAGING | 859 | ||
| MACROSCOPIC | 859 | ||
| MICROSCOPIC | 859 | ||
| ANCILLARY TESTS | 860 | ||
| DIFFERENTIAL DIAGNOSIS | 860 | ||
| STAGING | 860 | ||
| SELECTED REFERENCES | 860 | ||
| Tumors of Paratesticular Structures | 864 | ||
| Chapter 158. Adenomatoid Tumor | 864 | ||
| TERMINOLOGY | 865 | ||
| CLINICAL ISSUES | 865 | ||
| MACROSCOPIC | 865 | ||
| MICROSCOPIC | 865 | ||
| ANCILLARY TESTS | 865 | ||
| DIFFERENTIAL DIAGNOSIS | 865 | ||
| SELECTED REFERENCES | 865 | ||
| Chapter 159. Malignant Mesothelioma | 868 | ||
| TERMINOLOGY | 869 | ||
| ETIOLOGY/PATHOGENESIS | 869 | ||
| CLINICAL ISSUES | 869 | ||
| MACROSCOPIC | 869 | ||
| MICROSCOPIC | 869 | ||
| ANCILLARY TESTS | 869 | ||
| DIFFERENTIAL DIAGNOSIS | 869 | ||
| SELECTED REFERENCES | 869 | ||
| Chapter 160. Adenocarcinoma of Rete Testis/Epididymis | 872 | ||
| TERMINOLOGY | 873 | ||
| CLINICAL ISSUES | 873 | ||
| IMAGING | 873 | ||
| MACROSCOPIC | 873 | ||
| MICROSCOPIC | 873 | ||
| ANCILLARY TESTS | 873 | ||
| DIFFERENTIAL DIAGNOSIS | 873 | ||
| SELECTED REFERENCES | 873 | ||
| Chapter 161. Papillary Serous Carcinoma, Müllerian Subtype | 874 | ||
| TERMINOLOGY | 875 | ||
| ETIOLOGY/PATHOGENESIS | 875 | ||
| CLINICAL ISSUES | 875 | ||
| MACROSCOPIC | 875 | ||
| MICROSCOPIC | 875 | ||
| ANCILLARY TESTS | 875 | ||
| DIFFERENTIAL DIAGNOSIS | 875 | ||
| SELECTED REFERENCES | 875 | ||
| Chapter 162. Liposarcoma | 878 | ||
| TERMINOLOGY | 879 | ||
| CLINICAL ISSUES | 879 | ||
| IMAGING | 879 | ||
| MACROSCOPIC | 879 | ||
| MICROSCOPIC | 879 | ||
| ANCILLARY TESTS | 879 | ||
| DIFFERENTIAL DIAGNOSIS | 879 | ||
| SELECTED REFERENCES | 879 | ||
| Chapter 163. Melanotic Neuroectodermal Tumor | 882 | ||
| TERMINOLOGY | 883 | ||
| CLINICAL ISSUES | 883 | ||
| MACROSCOPIC | 883 | ||
| MICROSCOPIC | 883 | ||
| ANCILLARY TESTS | 883 | ||
| DIFFERENTIAL DIAGNOSIS | 883 | ||
| SELECTED REFERENCES | 883 | ||
| Chapter 164. Embryonal Rhabdomyosarcoma | 886 | ||
| TERMINOLOGY | 887 | ||
| CLINICAL ISSUES | 887 | ||
| MACROSCOPIC | 887 | ||
| MICROSCOPIC | 887 | ||
| ANCILLARY TESTS | 887 | ||
| DIFFERENTIAL DIAGNOSIS | 887 | ||
| SELECTED REFERENCES | 887 | ||
| Chapter 165. Other Sarcomas | 890 | ||
| TERMINOLOGY | 891 | ||
| CLINICAL ISSUES | 891 | ||
| IMAGING | 891 | ||
| MACROSCOPIC | 891 | ||
| MICROSCOPIC | 891 | ||
| ANCILLARY TESTS | 891 | ||
| DIFFERENTIAL DIAGNOSIS | 891 | ||
| SELECTED REFERENCES | 891 | ||
| Metastatic Tumors, Testis and Paratesticular Structures | 894 | ||
| Chapter 166. Metastatic Tumors, Testis and Paratesticular Structures | 894 | ||
| TERMINOLOGY | 895 | ||
| CLINICAL ISSUES | 895 | ||
| IMAGING | 895 | ||
| MACROSCOPIC | 895 | ||
| MICROSCOPIC | 895 | ||
| ANCILLARY TESTS | 895 | ||
| DIFFERENTIAL DIAGNOSIS | 895 | ||
| SELECTED REFERENCES | 895 | ||
| Immunohistochemical Profiles for Tumors Involving Testis\rand Paratesticular Structures | 898 | ||
| Chapter 167. Immunohistochemistry, Testis | 898 | ||
| SECTION 5:\rPenis and Scrotum | 906 | ||
| Frequent Lesions of Uncertain\rRelationship to Penile Neoplasia | 908 | ||
| Chapter 168. Condylomas | 908 | ||
| TERMINOLOGY | 909 | ||
| ETIOLOGY/PATHOGENESIS | 909 | ||
| CLINICAL ISSUES | 909 | ||
| MACROSCOPIC | 909 | ||
| MICROSCOPIC | 909 | ||
| DIFFERENTIAL DIAGNOSIS | 910 | ||
| DIAGNOSTIC CHECKLIST | 910 | ||
| SELECTED REFERENCES | 910 | ||
| Chapter 169. Lichen Sclerosus et Atrophicus | 912 | ||
| TERMINOLOGY | 913 | ||
| ETIOLOGY/PATHOGENESIS | 913 | ||
| CLINICAL ISSUES | 913 | ||
| MACROSCOPIC | 913 | ||
| MICROSCOPIC | 913 | ||
| DIFFERENTIAL DIAGNOSIS | 913 | ||
| DIAGNOSTIC CHECKLIST | 913 | ||
| SELECTED REFERENCES | 913 | ||
| Chapter 170. Squamous Hyperplasia | 914 | ||
| TERMINOLOGY | 915 | ||
| ETIOLOGY/PATHOGENESIS | 915 | ||
| CLINICAL ISSUES | 915 | ||
| MACROSCOPIC | 915 | ||
| MICROSCOPIC | 915 | ||
| DIFFERENTIAL DIAGNOSIS | 915 | ||
| SELECTED REFERENCES | 915 | ||
| Chapter 171. Lipogranuloma | 918 | ||
| TERMINOLOGY | 919 | ||
| ETIOLOGY/PATHOGENESIS | 919 | ||
| CLINICAL ISSUES | 919 | ||
| MACROSCOPIC | 919 | ||
| MICROSCOPIC | 919 | ||
| ANCILLARY TESTS | 919 | ||
| DIFFERENTIAL DIAGNOSIS | 919 | ||
| DIAGNOSTIC CHECKLIST | 919 | ||
| SELECTED REFERENCES | 919 | ||
| Chapter 172. Scrotal Calcinosis | 920 | ||
| TERMINOLOGY | 921 | ||
| ETIOLOGY/PATHOGENESIS | 921 | ||
| CLINICAL ISSUES | 921 | ||
| IMAGING | 921 | ||
| MICROSCOPIC | 921 | ||
| DIFFERENTIAL DIAGNOSIS | 921 | ||
| DIAGNOSTIC CHECKLIST | 921 | ||
| SELECTED REFERENCES | 921 | ||
| Penile Intraepithelial Neoplasia | 922 | ||
| Chapter 173. Penile Intraepithelial Neoplasia | 922 | ||
| TERMINOLOGY | 923 | ||
| ETIOLOGY/PATHOGENESIS | 923 | ||
| CLINICAL ISSUES | 923 | ||
| MACROSCOPIC | 923 | ||
| MICROSCOPIC | 923 | ||
| ANCILLARY TESTS | 923 | ||
| DIFFERENTIAL DIAGNOSIS | 924 | ||
| DIAGNOSTIC CHECKLIST | 924 | ||
| SELECTED REFERENCES | 924 | ||
| Primary Epithelial Tumors | 928 | ||
| Chapter 174. General Concepts, Squamous Cell Carcinoma | 928 | ||
| TERMINOLOGY | 928 | ||
| ANATOMY AND HISTOLOGY | 928 | ||
| EPIDEMIOLOGY | 928 | ||
| ETIOLOGY/PATHOGENESIS | 928 | ||
| MACROSCOPIC | 929 | ||
| MICROSCOPIC | 929 | ||
| PROGNOSTIC FACTORS | 930 | ||
| STAGING | 931 | ||
| SELECTED REFERENCES | 931 | ||
| Chapter 175. Squamous Cell Carcinoma, Usual Type | 938 | ||
| TERMINOLOGY | 939 | ||
| ETIOLOGY/PATHOGENESIS | 939 | ||
| CLINICAL ISSUES | 939 | ||
| MACROSCOPIC | 939 | ||
| MICROSCOPIC | 939 | ||
| DIFFERENTIAL DIAGNOSIS | 939 | ||
| SELECTED REFERENCES | 939 | ||
| Variants of Squamous Cell Carcinoma | 942 | ||
| Chapter 176. Basaloid Squamous Cell Carcinoma | 942 | ||
| TERMINOLOGY | 943 | ||
| ETIOLOGY/PATHOGENESIS | 943 | ||
| CLINICAL ISSUES | 943 | ||
| MACROSCOPIC | 943 | ||
| MICROSCOPIC | 943 | ||
| ANCILLARY TESTS | 943 | ||
| DIFFERENTIAL DIAGNOSIS | 943 | ||
| SELECTED REFERENCES | 943 | ||
| Chapter 177. Basaloid Squamous Cell Carcinoma, Papillary Variant | 946 | ||
| TERMINOLOGY | 947 | ||
| ETIOLOGY/PATHOGENESIS | 947 | ||
| CLINICAL ISSUES | 947 | ||
| MACROSCOPIC | 947 | ||
| MICROSCOPIC | 947 | ||
| ANCILLARY TESTS | 947 | ||
| DIFFERENTIAL DIAGNOSIS | 947 | ||
| DIAGNOSTIC CHECKLIST | 947 | ||
| SELECTED REFERENCES | 947 | ||
| Chapter 178. Warty (Condylomatous) Squamous Cell Carcinoma | 948 | ||
| TERMINOLOGY | 949 | ||
| ETIOLOGY/PATHOGENESIS | 949 | ||
| CLINICAL ISSUES | 949 | ||
| MACROSCOPIC | 949 | ||
| MICROSCOPIC | 949 | ||
| DIFFERENTIAL DIAGNOSIS | 949 | ||
| DIAGNOSTIC CHECKLIST | 950 | ||
| SELECTED REFERENCES | 950 | ||
| Chapter 179. Warty-Basaloid Squamous Cell Carcinoma | 952 | ||
| TERMINOLOGY | 953 | ||
| ETIOLOGY/PATHOGENESIS | 953 | ||
| CLINICAL ISSUES | 953 | ||
| MACROSCOPIC | 953 | ||
| MICROSCOPIC | 953 | ||
| ANCILLARY TESTS | 953 | ||
| DIFFERENTIAL DIAGNOSIS | 953 | ||
| DIAGNOSTIC CHECKLIST | 953 | ||
| SELECTED REFERENCES | 953 | ||
| Chapter 180. Verrucous Squamous Cell Carcinoma | 954 | ||
| TERMINOLOGY | 955 | ||
| ETIOLOGY/PATHOGENESIS | 955 | ||
| CLINICAL ISSUES | 955 | ||
| MACROSCOPIC | 955 | ||
| MICROSCOPIC | 955 | ||
| DIFFERENTIAL DIAGNOSIS | 955 | ||
| DIAGNOSTIC CHECKLIST | 955 | ||
| SELECTED REFERENCES | 955 | ||
| Chapter 181. Papillary Squamous Cell Carcinoma, Not Otherwise Specified | 958 | ||
| TERMINOLOGY | 959 | ||
| ETIOLOGY/PATHOGENESIS | 959 | ||
| CLINICAL ISSUES | 959 | ||
| MACROSCOPIC | 959 | ||
| MICROSCOPIC | 959 | ||
| DIFFERENTIAL DIAGNOSIS | 959 | ||
| SELECTED REFERENCES | 959 | ||
| Chapter 182. Pseudoglandular Squamous Cell Carcinoma | 962 | ||
| TERMINOLOGY | 963 | ||
| CLINICAL ISSUES | 963 | ||
| MACROSCOPIC | 963 | ||
| MICROSCOPIC | 963 | ||
| ANCILLARY TESTS | 963 | ||
| DIFFERENTIAL DIAGNOSIS | 963 | ||
| DIAGNOSTIC CHECKLIST | 963 | ||
| SELECTED REFERENCES | 963 | ||
| Chapter 183. Pseudohyperplastic Squamous Cell Carcinoma | 964 | ||
| TERMINOLOGY | 965 | ||
| ETIOLOGY/PATHOGENESIS | 965 | ||
| CLINICAL ISSUES | 965 | ||
| MACROSCOPIC | 965 | ||
| MICROSCOPIC | 965 | ||
| DIFFERENTIAL DIAGNOSIS | 965 | ||
| DIAGNOSTIC CHECKLIST | 965 | ||
| SELECTED REFERENCES | 965 | ||
| Chapter 184. Cuniculatum Squamous Cell Carcinoma | 966 | ||
| TERMINOLOGY | 967 | ||
| ETIOLOGY/PATHOGENESIS | 967 | ||
| CLINICAL ISSUES | 967 | ||
| MACROSCOPIC | 967 | ||
| MICROSCOPIC | 967 | ||
| DIFFERENTIAL DIAGNOSIS | 967 | ||
| DIAGNOSTIC CHECKLIST | 967 | ||
| SELECTED REFERENCES | 967 | ||
| Chapter 185. Sarcomatoid Squamous Cell Carcinoma | 970 | ||
| TERMINOLOGY | 971 | ||
| ETIOLOGY/PATHOGENESIS | 971 | ||
| CLINICAL ISSUES | 971 | ||
| MACROSCOPIC | 971 | ||
| MICROSCOPIC | 971 | ||
| ANCILLARY TESTS | 971 | ||
| DIFFERENTIAL DIAGNOSIS | 971 | ||
| DIAGNOSTIC CHECKLIST | 971 | ||
| SELECTED REFERENCES | 971 | ||
| Chapter 186. Mixed Squamous Cell Carcinoma | 974 | ||
| TERMINOLOGY | 975 | ||
| CLINICAL ISSUES | 975 | ||
| MACROSCOPIC | 975 | ||
| MICROSCOPIC | 975 | ||
| DIFFERENTIAL DIAGNOSIS | 975 | ||
| SELECTED REFERENCES | 975 | ||
| Chapter 187. Lymphoepithelioma-Like Squamous Cell Carcinoma | 978 | ||
| TERMINOLOGY | 979 | ||
| ETIOLOGY/PATHOGENESIS | 979 | ||
| CLINICAL ISSUES | 979 | ||
| MACROSCOPIC | 979 | ||
| MICROSCOPIC | 979 | ||
| ANCILLARY TESTS | 979 | ||
| DIFFERENTIAL DIAGNOSIS | 979 | ||
| DIAGNOSTIC CHECKLIST | 979 | ||
| SELECTED REFERENCES | 979 | ||
| Chapter 188. Clear Cell Carcinoma | 980 | ||
| TERMINOLOGY | 981 | ||
| ETIOLOGY/PATHOGENESIS | 981 | ||
| CLINICAL ISSUES | 981 | ||
| MACROSCOPIC | 981 | ||
| MICROSCOPIC | 981 | ||
| ANCILLARY TESTS | 981 | ||
| DIFFERENTIAL DIAGNOSIS | 981 | ||
| DIAGNOSTIC CHECKLIST | 981 | ||
| SELECTED REFERENCES | 981 | ||
| HPV- and Non-HPV-Related Tumors | 982 | ||
| Chapter 189. Overview of HPV- and Non-HPV-Related Tumors | 982 | ||
| TERMINOLOGY | 983 | ||
| ETIOLOGY/PATHOGENESIS | 983 | ||
| CLINICAL ISSUES | 983 | ||
| MACROSCOPIC | 983 | ||
| MICROSCOPIC | 983 | ||
| ANCILLARY TESTS | 984 | ||
| SELECTED REFERENCES | 984 | ||
| Other Neoplastic Conditions | 986 | ||
| Chapter 190. Extramammary Paget Disease | 986 | ||
| TERMINOLOGY | 987 | ||
| ETIOLOGY/PATHOGENESIS | 987 | ||
| CLINICAL ISSUES | 987 | ||
| MACROSCOPIC | 987 | ||
| MICROSCOPIC | 987 | ||
| ANCILLARY TESTS | 987 | ||
| DIFFERENTIAL DIAGNOSIS | 988 | ||
| DIAGNOSTIC CHECKLIST | 988 | ||
| SELECTED REFERENCES | 988 | ||
| Chapter 191. Kaposi Sarcoma | 990 | ||
| TERMINOLOGY | 991 | ||
| ETIOLOGY/PATHOGENESIS | 991 | ||
| CLINICAL ISSUES | 991 | ||
| MACROSCOPIC | 991 | ||
| MICROSCOPIC | 991 | ||
| DIFFERENTIAL DIAGNOSIS | 991 | ||
| DIAGNOSTIC CHECKLIST | 991 | ||
| SELECTED REFERENCES | 991 | ||
| Chapter 192. Myointimoma | 992 | ||
| TERMINOLOGY | 993 | ||
| CLINICAL ISSUES | 993 | ||
| MACROSCOPIC | 993 | ||
| MICROSCOPIC | 993 | ||
| ANCILLARY TESTS | 993 | ||
| DIFFERENTIAL DIAGNOSIS | 993 | ||
| DIAGNOSTIC CHECKLIST | 993 | ||
| SELECTED REFERENCES | 993 | ||
| Metastatic Tumors | 994 | ||
| Chapter 193. Metastatic Tumors, Penis | 994 | ||
| TERMINOLOGY | 995 | ||
| ETIOLOGY/PATHOGENESIS | 995 | ||
| CLINICAL ISSUES | 995 | ||
| IMAGING | 995 | ||
| MACROSCOPIC | 995 | ||
| MICROSCOPIC | 995 | ||
| DIFFERENTIAL DIAGNOSIS | 995 | ||
| DIAGNOSTIC CHECKLIST | 995 | ||
| SELECTED REFERENCES | 995 | ||
| Immunohistochemical Profiles for Tumors Involving Penis | 996 | ||
| Chapter 194. Immunohistochemistry, Penis | 996 | ||
| INDEX | I-i |