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Cardioembolic Stroke, An Issue of Cardiology Clinics, E-Book

Cardioembolic Stroke, An Issue of Cardiology Clinics, E-Book

Ranjan K. Thakur | Ziyad M. Hijazi | Andrea Natale

(2016)

Additional Information

Book Details

Abstract

This issue of the Cardiology Clinics, edited by Ranjan K. Thakur, Andrea Natale, and Ziyad Hijazi, focuses on Cardioembolic Stroke. Topics covered in this issue include, but are not limited to: epidemiology of atrial fibrillation and stroke, atrial fibrillation and stroke, device detected atrial fibrillation, left atrial appendage closure for stroke prevention, cryptogenic strokes, and atrial fibrillation and cognitive decline.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Cardioembolic Stroke\r i
Copyright\r ii
Contributors iii
EDITORIAL BOARD iii
EDITORS iii
AUTHORS iii
Contents vii
Preface: Cardioembolic Stroke\r vii
Cardioembolic Stroke and Postmyocardial Infarction Stroke\r vii
Embolic Stroke in Cardiomyopathy: Should Patients be Anticoagulated?\r vii
Atrial Septal Defects and Cardioembolic Strokes\r vii
Patent Foramen Ovale: Stroke and Device Closure\r vii
Pulmonary Arteriovenous Malformations and Risk of Stroke\r viii
Congenital Malformations Leading to Paradoxical Embolism\r viii
The Epidemiology of Atrial Fibrillation and Stroke\r viii
Radiological Portrait of Embolic Strokes\r viii
Atrial Fibrillation and Cognitive Decline: Phenomenon or Epiphenomenon?\r ix
Cardiac Monitoring for Atrial Fibrillation in Cryptogenic Stroke\r ix
Device-Detected Atrial Fibrillation—Perils and Pitfalls: An Update\r ix
Atrial Fibrillation Ablation and Stroke\r ix
Atrial Fibrillation and Stroke: Making Sense of Recent Observations on Anticoagulation\r x
Left Atrial Appendage Closure for Stroke Prevention: Devices, Techniques, and Efficacy\r x
CARDIOLOGY CLINICS\r xi
FORTHCOMING ISSUES xi
August 2016 xi
November 2016 xi
February 2017 xi
RECENT ISSUES xi
February 2016 xi
November 2015 xi
August 2015 xi
Preface: Cardioembolic Stroke\r xiii
Cardioembolic Stroke and Postmyocardial Infarction Stroke 207
Key points 207
INTRODUCTION 207
NONCARDIOEMBOLIC STROKES FOLLOWING ACUTE MYOCARDIAL INFARCTION 208
CARDIOEMBOLIC STROKES FOLLOWING MYOCARDIAL INFARCTION 208
Left Ventricular Thrombus Formation 208
Atrial Fibrillation 209
SUMMARY 211
REFERENCES 211
Embolic Stroke in Cardiomyopathy 215
Key points 215
INTRODUCTION 215
EPIDEMIOLOGY OF STROKE IN HEART FAILURE 215
PATHOGENESIS OF STROKE IN HEART FAILURE 217
ANTICOAGULATION IN PATIENTS WITH HEART FAILURE IN SINUS RHYTHM 218
ANTICOAGULATION IN PATIENTS WITH HEART FAILURE IN ATRIAL FIBRILLATION 220
NOVEL ORAL ANTICOAGULATION IN HEART FAILURE 221
GUIDELINES FOR ANTICOAGULATION IN HEART FAILURE 221
SUMMARY 222
REFERENCES 222
Atrial Septal Defects and Cardioembolic Strokes 225
Key points 225
BACKGROUND AND PRESENTATION 225
EPIDEMIOLOGY OF STROKE IN ATRIAL SEPTAL DEFECTS 226
CAUSES OF STROKE 226
MANAGEMENT 227
Closure 227
Medical Management 229
REFERENCES 229
Patent Foramen Ovale 231
Key points 231
INTRODUCTION 231
ASSOCIATION BETWEEN PATENT FORAMEN OVALE AND CRYPTOGENIC STROKE 231
PATENT FORAMEN OVALE AND RECURRENT STROKE 232
MANAGEMENT OPTIONS FOR PATENT FORAMEN OVALE IN STROKE 233
Medical Therapy 233
Surgical Therapy 233
Percutaneous Therapy 234
Randomized Trials Evidence 234
First trial 234
Second trial 236
Third Trial 236
Limitations of the Randomized Trials 236
Management Approach for Cryptogenic Stroke and Patent Foramen Ovale 237
Ongoing Studies 238
SUMMARY 238
REFERENCES 239
Pulmonary Arteriovenous Malformations and Risk of Stroke 241
Key points 241
INTRODUCTION 241
CLINICAL FINDINGS AND DIAGNOSIS 241
THERAPEUTIC CONSIDERATIONS 244
TRANSCATHETER THERAPY 244
SUMMARY 245
REFERENCES 246
Congenital Malformations Leading to Paradoxical Embolism 247
Key points 247
INTRODUCTION 247
ISOLATED SYSTEMIC VENOUS ABNORMALITIES AND PARADOXICAL EMBOLI 248
Persistent Left Superior Vena Cava 248
Right Superior Vena Cava Draining to the Left Atrium 248
Inferior Vena Cava “Draining to the Left Atrium” 248
Ductus Venosus 248
UNIVENTRICULAR HEARTS AND PARADOXICAL EMBOLI 249
BIVENTRICULAR HEARTS AND PARADOXICAL EMBOLI 250
SUMMARY 252
REFERENCES 252
The Epidemiology of Atrial Fibrillation and Stroke 255
Key points 255
INTRODUCTION 255
EPIDEMIOLOGY OF ATRIAL FIBRILLATION 256
EPIDEMIOLOGY OF STROKE 257
EPIDEMIOLOGY OF ISCHEMIC STROKE SUBTYPES AND LINK WITH ATRIAL FIBRILLATION 257
REFERENCES 264
Radiological Portrait of Embolic Strokes 269
Key points 269
INTRODUCTION 269
CLINICAL PRESENTATION OF EMBOLIC STROKES 270
EMERGENCY MANAGEMENT OF ACUTE STROKE 270
IMAGING MODALITIES IN ACUTE STROKE 273
IMAGING APPEARANCE OF CARDIOEMBOLIC STROKE 273
SUMMARY 277
REFERENCES 277
Atrial Fibrillation and Cognitive Decline 279
Key points 279
INTRODUCTION 279
ATRIAL FIBRILLATION AND COGNITIVE IMPAIRMENT 279
MECHANISMS UNDERLYING THE ASSOCIATION BETWEEN ATRIAL FIBRILLATION AND COGNITIVE IMPAIRMENT 280
Hypercoagulable States and Brain Infarcts 280
Proinflammatory State 282
Changes in Brain Perfusion 282
Brain Morphometric Changes 283
DISCUSSION/SUMMARY 283
REFERENCES 284
Cardiac Monitoring for Atrial Fibrillation in Cryptogenic Stroke 287
Key points 287
BACKGROUND 287
OBSERVATIONAL STUDIES OF EXTERNAL MONITORS: INPATIENT MONITORING 288
OBSERVATIONAL STUDIES OF EXTERNAL MONITORS: HOLTER MONITORING 288
OBSERVATIONAL STUDIES OF EXTERNAL MONITORS: OUTPATIENT EVENT MONITORING 289
OBSERVATIONAL STUDIES OF EXTERNAL MONITORS: OUTPATIENT MOBILE CARDIAC TELEMETRY MONITORING 290
RANDOMIZED CONTROLLED TRIALS COMPARING EXTERNAL MONITORING STRATEGIES 290
OBSERVATIONAL STUDIES OF INSERTABLE CARDIAC MONITORS 291
RANDOMIZED CONTROLLED TRIALS OF INSERTABLE CARDIAC MONITORS VERSUS EXTERNAL MONITORS 292
META-ANALYSES OF MONITORING TECHNIQUES 293
COST-EFFECTIVENESS OF MONITORING 295
FUTURE IMPLICATIONS 295
REFERENCES 296
Device-Detected Atrial Fibrillation—Perils and Pitfalls 299
Key points 299
INTRODUCTION 299
ATRIAL FIBRILLATION AS A RISK FACTOR FOR STROKE 300
ATRIAL HIGH-RATE EVENTS AND ATRIAL FIBRILLATION 300
ATRIAL HIGH-RATE EVENTS AND THROMBOEMBOLISM 302
UNANSWERED QUESTIONS 304
SUMMARY 305
REFERENCES 305
Atrial Fibrillation Ablation and Stroke 307
Key points 307
INTRODUCTION 307
CEREBROVASCULAR COMPLICATIONS OF CATHETER ABLATION 308
Stroke and Transient Ischemic Attack 308
Silent Cerebral Ischemia 308
Mechanisms of Silent Cerebral Ischemia 309
PERIPROCEDURAL ANTICOAGULATION 310
OTHER FACTORS HAVING AN IMPACT ON THE RISK OF PERIPROCEDURAL EMBOLIC EVENTS 311
Patient Characteristics 311
Ablation Energy Source 312
Sheaths and Catheters 312
Ablation Protocol and Periprocedural Cardioversion 312
SUMMARY 313
REFERENCES 313
Atrial Fibrillation and Stroke 317
Key points 317
INTRODUCTION 317
A BRIEF OVERVIEW OF CURRENT CLINICAL GUIDELINES 318
MAKING SENSE OF RECENT OBSERVATIONS ON AN ORAL ANTICOAGULANT FOR STROKE PREVENTION 320
Gender 320
Ethnicity 320
Age 321
Chronic Kidney Disease 321
Coronary and Peripheral Vascular Disease 322
Perioperative Management 322
FROM TRIALS TO REAL-WORLD CLINICAL PRACTICE 323
SUMMARY 323
REFERENCES 324
Left Atrial Appendage Closure for Stroke Prevention 329
Key points 329
INTRODUCTION 329
LEFT ATRIAL APPENDAGE ANATOMY AND PHYSIOLOGY 330
Variation in Left Atrial Appendage Anatomy 330
FUNCTION 330
Contractility 330
Fluid Hemostasis 330
LEFT ATRIAL APPENDAGE EXCLUSION: SURGICAL APPROACH 330
Endocardial Suture Closure 332
Stapler Occlusion 332
Epicardial Clip Closure 332
Procedure 332
Efficacy 333
PERCUTANEOUS APPROACH 333
Basic Concept of Percutaneous Left Atrial Appendage Closure Procedure 333
Preprocedural Imaging 333
Transseptal Access 333
WATCHMAN (BOSTON SCIENTIFIC, NATICK, MA, USA) 333
Device 334
Data 334
Anticoagulation 334
Procedure 335
Preprocedural imaging and transseptal puncture as previously described 335
Implantation of the WATCHMAN device 335
Device release 336
Complications 336
Pericardial effusion 336
Air embolism 336
Thrombus formation during device implantation 336
Early device embolization 336
Late device embolization 336
Leak 336
AMPLATZER CARDIAC PLUG (ST. JUDE MEDICAL, ST. PAUL, MN, USA) 337
Amulet (St. Jude Medical) 338
Preprocedural imaging 338
Size selection 338
Amplatzer cardiac plug sizing 338
Procedural technique 338
Access sheath advancement 338
Device deployment and release 338
Data 338
Complications 339
Device embolization 339
Perforation 339
PERCUTANEOUS LEFT ATRIAL APPENDAGE TRANSCATHETER OCCLUSION (APPRIVA MEDICAL INC, SUNNYVALE, CA, USA) 340
Index 353