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Emergency Neuro-Otology: Diagnosis and Management of Acute Dizziness and Vertigo, An Issue of Neurologic Clinics, E-Book

Emergency Neuro-Otology: Diagnosis and Management of Acute Dizziness and Vertigo, An Issue of Neurologic Clinics, E-Book

David E. Newman-Toker

(2015)

Abstract

The focus of this publication on Neuro-Otology in Neurologic Clinics is on the patient presenting for urgent or emergent care with a chief complaint of new, previously-undiagnosed dizziness or vertigo. Intent is to emphasize throughout the issue five primary components of initial diagnosis and management: (1) Epidemiology, differential diagnosis, and disease definitions; (2) Bedside clinical features that differentiate dangerous from benign causes; (3) Appropriate use of advanced diagnostic tests (including imaging, vestibular tests) and consultations; (4) Application of early treatments (manipulative, pharmacologic, rehabilitative); and (5) Acute disposition strategies, including determining need for admission and urgency of follow-up. Articles have a consistent architecture to highlight key points: 1) Case Scenario (with a representative case example; videos are presented with many of these); 2) Prevalence & Pathomechanisms; 3) Definitions & Diagnostic Criteria; 4) Bedside & Laboratory Diagnostic Tests; 5) Acute Treatment Options (including manipulative, pharmacologic, rehabilitative); and 6) Triage & Disposition (including referrals and follow-up). The articles are presented with four major parts: Overall approach to acute dizziness and vertigo; Episodic vertigo and dizziness; Acute, continuous vertigo and dizziness; and Case unknowns. Among the topics covered are: Bedside evaluation; Transient ischemic attacks; Vestibularl neuritis and labyrinthitis; Stroke; Novel approach to diagnosing the acutely dizzy patient. David Newman-Toker leads this publication with associate editors renown in their fields - Kevin Kerber, William J. Meurer, Rodney Omron, and Jonathan Edlow.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Emergency Neuro-Otology: Diagnosis and Management of Acute Dizziness and Vertigo\r i
Copyright\r ii
Contributors iii
Contents vii
Forthcoming Issues xii
Preface\r xiii
Overview of the International Classification of Vestibular Disorders 541
Key points 541
Introduction 541
Goals and scope for the International Classification of Vestibular Disorders initiative 542
Methodology and process for developing the International Classification of Vestibular Disorders 543
International Classification of Vestibular Disorders structure 545
International Classification of Vestibular Disorders layer I: symptoms and signs 545
International Classification of Vestibular Disorders layer II: syndromes 546
International Classification of Vestibular Disorders layer III: disorders and diseases 547
International Classification of Vestibular Disorders layer III-B: mechanisms 548
International Classification of Vestibular Disorders and functional outcomes 548
Summary 549
Acknowledgment 549
References 549
Bedside Assessment of Acute Dizziness and Vertigo 551
Key points 551
Introduction 552
The history 552
Is It Truly Vertigo? 552
Is It the First Ever Attack or Is It Long-standing Recurrent Vertigo? 552
Is It Spontaneous or Positional? 552
What Is the Duration of Each Spell? 553
What Are the Associated Symptoms? 553
Do Recent Events Provide a Clue? 553
The physical examination 553
The General Inspection 553
Inspection for Spontaneous and Gaze-evoked Nystagmus 554
Provocative Testing for Positional Nystagmus 555
Head-shaking nystagmus 558
The Head Impulse 559
Oculomotor Examination 560
Test horizontal and vertical saccades 560
Test pursuit 560
Visual cancellation of the vestibulo-ocular reflex 560
Vestibulospinal Reflexes 561
General Neurologic Assessment 561
Postural Blood Pressure, Pulse, and Auscultation 561
What might be seen in a patient presenting with acute vestibular syndrome 561
Vestibular Neuritis 561
Cerebellar Stroke 561
What might be seen in episodic spontaneous vertigo 562
Meniere Disease 562
Vestibular Migraine 562
What might be seen in the patient with recurrent positional vertigo 562
Benign Positional Vertigo 562
When the patient is acutely dizzy and there are no physical signs to find 563
Future directions in acute vertigo 563
Supplementary data 563
References 563
Misdiagnosing Dizzy Patients 565
Key points 565
Introduction 565
Pitfall 1: overreliance on the type of dizziness to guide diagnostic inquiry 566
Pitfall 2: underuse and misuse of timing and triggers to categorize patients for diagnosis 568
Pitfall 3: underuse, misuse, and misconceptions linked to hallmark eye examination findings 569
Pitfall 4: overweighting age, vascular risk factors, and general neurologic examination to screen for stroke 571
Pitfall 5: overuse and overreliance on head computed tomography to rule out neurologic causes 571
Summary 572
Acknowledgments 573
References 573
TiTrATE 577
Key points 577
Introduction 577
New diagnostic approach 578
Four vestibular syndromes 581
Episodic Vestibular Syndrome 581
Triggered episodic vestibular syndrome 581
Approach 581
Diseases 586
Spontaneous episodic vestibular syndrome 586
Approach 586
Diseases 587
Acute Vestibular Syndrome 588
Traumatic/toxic acute vestibular syndrome 588
Approach 588
Diseases 589
Spontaneous acute vestibular syndrome 589
Approach 589
Diseases 590
Bedside approach summary 591
Summary 591
Acknowledgments 591
Appendix 592
References 592
Benign Paroxysmal Positional Vertigo in the Acute Care Setting 601
Key points 601
Case scenario 601
Epidemiology 602
Pathophysiology 602
Early Diagnosis and Management of Acute Vertigo from Vestibular Migraine and Ménière's Disease 619
Key points 619
Vestibular migraine 619
Case Scenario 619
Prevalence and Pathophysiologic Mechanisms 620
Neuroanatomic regions implicated 620
Definitions and Diagnostic Criteria (Differentiation from transient ischaemic attack [TIA] + Approach to Initial Diagnosis) 621
Bedside and Laboratory Diagnostic Tests 621
History 621
The examination 623
Laboratory test 623
Immediate Treatment Options 623
Triage and Disposition 623
Prophylaxis 623
Ménière’s disease 623
Case Scenario 623
Prevalence and Pathophysiologic Mechanisms 624
Definitions and Diagnostic Criteria (Differentiation from TIA + Approach to Initial Diagnosis) 624
Bedside and Laboratory Diagnostic Tests 624
Immediate Treatment Options (Including Manipulative and Pharmacologic [Rehabilitative]) 625
Triage and Disposition 625
When to refer 626
References 626
Transient Ischemic Attacks Presenting with Dizziness or Vertigo 629
Key points 629
Case scenario 629
Introduction 630
Prevalence and pathomechanisms 631
Definitions 633
Diagnostic approach: bedside and laboratory testing 634
History and Examination 634
Diagnostic Evaluation 634
Laboratory Tests 636
Acute treatment options 636
Blood Pressure 636
Medical Therapy 637
Antithrombotic medications 637
Statins 637
Revascularization 637
Triage and disposition 638
Summary 639
References 639
Medical and Psychiatric Causes of Episodic Vestibular Symptoms 643
Key points 643
Case scenario 643
Introduction 644
Definitions 645
Epidemiology 645
Bedside diagnosis 645
History 646
Physical Examination 646
Initial Management and Further Diagnostic Testing 647
Specific conditions that can cause episodic dizziness 647
Orthostatic Hypotension 647
Postural Tachycardia Syndrome 648
Syncope/presyncope (arrhythmia/neutrally mediated syncope) 648
Medication effects 649
Hypoglycemia and toxic/metabolic causes 651
Visual disorders 651
Cervical spondylosis 651
Panic attacks and anxiety disorders 652
Fibromyalgia 653
Hyperventilation 653
Summary 656
References 656
Early Diagnosis and Treatment of Traumatic Vestibulopathy and Postconcussive Dizziness 661
Key points 661
Introduction 661
The definition of mild traumatic brain injury 662
Epidemiology 662
Balance disorders after blast injuries 663
Balance disorders after blunt head injury 664
Diagnosis 664
Treatment 665
Summary 666
References 666
Acute Unilateral Vestibulopathy 669
Key points 669
Case scenario 669
Prevalence and pathomechanisms 670
Epidemiology 670
Etiology 670
Pathophysiology 671
Peripheral vestibular spontaneous nystagmus 671
Lesion location 671
Definitions and diagnostic criteria, bedside and laboratory diagnostic tests 672
Laboratory Diagnostic Tests 675
Caloric testing 675
Video head-impulse test 675
Cervical and ocular vestibular-evoked myogenic potentials 675
Differential Diagnosis and Other Clinical Problems 675
Central lesions mimicking acute unilateral vestibulopathy 676
Peripheral vestibular lesions 677
Short-term treatment options (including manipulative, pharmacologic, rehabilitative) 678
Symptomatic Treatment and Improvement of Central Compensation 678
Causative Treatment 681
Vestibular Physical Therapy 682
Supplementary data 683
References 683
Acute Diagnosis and Management of Stroke Presenting Dizziness or Vertigo 687
Key points 687
Case (Wallenberg syndrome) 687
Prevalence and pathomechanism 688
Stroke Presenting with Acute Vestibular Syndrome 689
Diagnosis and classification of strokes 689
Cerebellar Infarction 689
Posterior inferior cerebellar artery infarction 689
Anterior inferior cerebellar artery infarction 692
Superior cerebellar artery stroke 692
Medullary Infarction 692
Lateral medullary infarction (Wallenberg syndrome) 692
Medial medullary infarction 693
Vestibular nuclear infarct 693
Bedside and laboratory diagnostic tests 693
Bedside Evaluation 693
Laboratory Tests 694
Acute treatment options 695
General Principle 695
Medical Treatments 695
Surgical Treatments 696
Rehabilitation 696
Triage and disposition 696
Supplementary data 696
References 697
Medical and Nonstroke Neurologic Causes of Acute, Continuous Vestibular Symptoms 699
Key points 699
Introduction 699
General medical conditions without obvious structural neurologic disease 700
Pharmacologic Toxicity and Withdrawal 702
Environmental Toxins 703
Electrolyte, Endocrine, and Micronutrient Disturbances 703
Cardiovascular, Respiratory, Rheological, and Hematologic Disturbances 705
Nonstroke neurologic conditions 706
Demyelinating Disease, Especially Multiple Sclerosis 706
Posterior Fossa Neoplasms and Other Mass Lesions 706
Brainstem/Cerebellar Encephalitis (Infectious and Autoimmune Conditions) 707
Disorders of Intracranial Pressure and Brain Edema 709
Physiologic unmasking of occult or recovered neurologic disease 710
Summary 710
Acknowledgments 711
References 711
Index 717