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Atlas of Diagnostic Oncology E-Book

Atlas of Diagnostic Oncology E-Book

Arthur T. Skarin

(2015)

Additional Information

Book Details

Abstract

Atlas of Diagnostic Oncology, 4th Edition, by Arthur T. Skarin, MD, FACP, FCCP, provides the guidance you need to diagnose a full range of neoplastic conditions with greater accuracy for better patient outcomes. An unrivaled collection of more than 2,500 images and drawings—combined with succinct, clinically focused text—equips you with essential information on pathology, diagnostic studies, staging, and clinical manifestations. New discussions on modern diagnostic PET imaging of cancer, and expanded coverage on the side effects of chemotherapy, bring you up to date on the issues impacting research and treatment. Expert Consult functionality—new to this edition—further enhances your reference power with convenient online access to the complete contents of the text, along with case studies that demonstrate effective approaches to diagnosis.

  • A superb collection of more than 2,500 images encompasses the full spectrum of pathologic and radiologic studies, staging, and clinical manifestations, highlighting the pathologic anatomy of common clinical entities.
  • A consistent chapter organization covers each disease’s incidence, epidemiology, etiology, and histopathology — as well as molecular biology, clinical features, diagnostic studies, and current clinical and pathologic staging — providing all the assistance you need to evaluate and monitor your patients effectively.
  • This unique pictorial resource is a superb complement to treatment handbooks and major oncological texts.
  • Expert Consult functionality provides online access to the complete text, fully searchable, with illustrations downloadable for your personal presentations, and case studies keyed to the book, at expertconsult.com.
  • Completely updated chapters covering the newest genetic markers, imaging modalities, and pathologic techniques enable you to get the best results from today’s diagnostic tools.
  • An expanded chapter on evaluating the side effects of chemotherapy, with additional images of reactions to the newest regimens, alerts you to potential common and uncommon side effects.
  • Two new chapters address the complications of cancer and modern use of diagnostic PET scans, keeping you up to date on these hotly debated topics in the oncology community.
  • A third new chapter covers malignant mesothelioma of the lung, plus other sites.

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Table of Contents

Section Title Page Action Price
Front Cover Cover
Atlas of Diagnostic Oncology i
Dana-Farber Cancer InstituteAtlas of Diagnostic Oncology iii
Copyright iv
Contents v
Preface ix
Foreword vii
Contributors xi
Acknowledgments xv
Introduction xvii
References and Suggested Readings xix
Chapter 1: The Role of Molecular Probes and Other Markers in the Diagnosis of Malignancy 1
References and Suggested Readings 5
Chapter 2: Radiographic Evaluation of Cancer 6
Imaging Goals 6
Plain Radiography 7
Gastrointestinal Contrast Studies 9
Intravenous Contrast Studies 9
Mammography 9
Ultrasound 11
Computed Tomography 12
Computed Tomography as a Screening Tool 19
Positron Emission Tomography–Computed Tomography 20
Magnetic Resonance Imaging 22
Image-Guided Biopsy 26
Image-Guided Therapy 26
Conclusions 27
References and Suggested Readings 28
Chapter 3: Nuclear Medicine in Oncology 30
Bone Scan 31
Positron Emission Tomography 36
Thyroid Cancer 41
Neuroendocrine Tumors 45
Gallium-67 and 99mTc-SestaMIBI 46
Sentinel Nodes 52
Radioisotope Therapy 53
Assessing Nontarget Organ Response to Therapy 56
References and Suggested Readings 59
Chapter 4: Cancer of the Head and Neck region 60
Histology 60
Salivary Gland Tumors 61
Less Frequently Encountered Neoplasms 62
Molecular Biology 62
Staging of Head and Neck Cancers 73
Clinical Manifestations 74
Lips 74
Oral Cavity 75
Nasopharynx 74
Oropharynx 75
Hypopharynx 75
Larynx 76
Nasal Cavity and Paranasal Sinuses 75
Major and Minor Salivary Glands 76
References and Suggested Readings 96
Chapter 5: Lung Cancer and Tumors of the Heart and Mediastinum 98
Lung Cancer 98
Tumors of the Heart 104
Tumors of the Mediastinum 105
References and Suggested Readings 157
Figure Credits 159
Chapter 6: Malignant Mesothelioma 160
Clinical Presentation 160
Diagnostic Evaluation 161
Staging 166
Prognostic Factors 167
Treatment 167
Surgery 167
Chemotherapy 168
Irradiation 167
References and Suggested Readings 167
Chapter 7: Cancer of the Gastrointestinal Tract and Neuroendocrine Tumors 169
Esophageal Cancers 169
Gastric Cancers 177
Pancreatic Cancers 185
Hepatobiliary Cancers 195
Cancers of the Small Intestine 203
Colorectal Cancers 212
Anal Cancers 214
References and Suggested Readings 232
Chapter 8: Cancer of the Genitourinary Tract 233
Prostate Cancer 233
Bladder Cancer 234
Kidney Cancer 235
Testicular Cancer 237
Penile Cancer 238
References and Suggested Readings 276
Figure Credits 277
Chapter 9: Gynecologic Tumors and Malignancies 278
Ovarian Carcinoma 278
Endometrial Carcinoma 295
Cervical Cancer 307
Other Gynecologic Malignancies 313
References and Suggested Readings 323
Figure Credits 324
Chapter 10: Breast Cancer 325
Incidence 326
Screening 326
Histology 327
Diagnosis and Staging of Breast Cancer 327
Primary Treatment 327
Metastatic Breast Cancer/Locally Recurrent Disease 328
References and Suggested Readings 363
Figure Credits 364
Chapter 11: Endocrine Neoplasia 365
Cancer of the Thyroid Gland 365
Tumors of the Adrenal Gland 377
Pheochromocytoma 382
Paraganglioma 383
Tumors of the Pituitary Gland 388
Neuroendocrine Tumors 393
Islet Cell Tumors 397
Multiple Endocrine Neoplasia Syndrome 399
References and Suggested Readings 401
Figure Credits 402
Chapter 12: Sarcomas of Soft Tissue and Bone and Gastrointestinal Stromal Tumors 403
Sarcomas 403
Gastrointestinal Stromal Tumors 439
References and Suggested Readings 444
Figure Credits 445
Chapter 13: Skin Cancer 446
Benign Skin Tumors 446
Premalignant Skin Tumors 449
Common Skin Cancers 452
Miscellaneous Skin Cancers 475
References and Suggested Readings 482
Figure Credits 483
Chapter 14: Neoplasms of the Central Nervous System 484
Primary Neoplasms of the Central Nervous System 487
Tumors of Cranial and Spinal Nerves 508
Tumors of the Meninges 511
Lymphomas and Hematopoietic Neoplasms 518
Germ Cell Tumors 518
Tumors of the Sellar Region 520
Local Extension from Regional Tumors 522
Metastatic Tumors 523
References and Suggested Readings 527
Figure Credits 528
Chapter 15: Acute and Chronic Leukemias 639
Acute Leukemias 529
Hematologic Disorders with a Tendency to Leukemic Transformation 550
Chronic Leukemias 555
References and suggested readings 569
Figure Credits 570
Chapter 16 :Hodgkin Disease and Non-Hodgkin Lymphomas 571
Hodgkin Disease 571
Non-Hodgkin Lymphoma 587
References and Suggested Readings 637
Figure Credits 639
Chapter 17: Multiple Myeloma and Plasma Cell Dyscrasias 640
Multiple Myeloma 640
Plasma Cell Leukemia 642
Monoclonal Gammopathy of Undetermined Significance 642
Waldenstrom’s Macroglobulinemia 642
Heavy-Chain Disorders 642
Acknowledgments 643
References and Suggested Readings 666
Figure Credits 666
Chapter 18: Solid Tumors in Childhood 667
Retinoblastoma 667
Wilms’ Tumor 668
Neuroblastoma 668
Hepatic Tumors 669
Rhabdomyosarcoma 669
The Ewing Family of Tumors 670
Osteosarcoma 670
References and Suggested Readings 692
Chapter 19: AIDS-Associated Malignancies 694
Pathogenesis of AIDS-Related Neoplasms 694
Kaposi Sarcoma 695
Non-Hodgkin Lymphoma 695
Hodgkin Lymphoma 697
Squamous Epithelial Lesions 698
References and Suggested Readings 708
Chapter 20: Complications of Cancer 709
Infectious Complications 709
Metabolic Complications 710
Hematologic Complications 711
Vascular Complications 712
Neurologic Complications 712
Structural Complications 714
References and Suggested Readings 720
Chapter 21: Systemic and Mucocutaneous Reactions to Chemotherapy 734
Acute Hypersensitivity Reactions 721
Alopecia 722
Stomatitis/Mucositis 723
Dermatitis, Skin Rashes, and Hyperpigmentation 724
Skin Ulceration and Extravasation 727
Nail Changes 728
Radiation Recall 729
Hand-Foot Syndrome/Erythromelalgia 730
Organ Toxicity 730
Late Complications of Cancer Chemotherapy 733
References and Selected Readings 736
Further Reading 736
Index 737
A 737
B 738
C 740
D 742
E 743
F 744
G 744
H 745
I 745
J 746
K 746
L 746
M 747
N 749
O 749
P 750
R 751
S 752
T 754
U 754
V 755
W 755
X 755
Y 755
Z 755