BOOK
A Global Perspective/Health Inequity in Heart Failure, An Issue of Heart Failure Clinics, E-Book
(2016)
Additional Information
Book Details
Abstract
This special issue of Heart Failure Clinics examines heart failure with a truly global perspective, exposing health inequities in the treatment of heart failure.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
A Global Perspective/HealthInequity in Heart Failure \r | i | ||
Copyright\r | i | ||
Contributors | iii | ||
CONSULTING EDITORS | iii | ||
EDITORS | iii | ||
AUTHORS | iii | ||
Contents | vii | ||
Foreword: Heart Failure: A Global Pandemic and Not Just a Disease of the West\r | vii | ||
Socioeconomic Inequalities in Heart Failure\r | vii | ||
Heart Failure in Rural Communities\r | vii | ||
Inequalities in the Access to Advanced Therapy in Heart Failure\r | vii | ||
Gaps and Resemblances in Current Heart Failure Guidelines: A Clinical Perspective\r | vii | ||
Prognostic Factors in Hospitalization for Heart Failure in Asia\r | viii | ||
Biomarkers for Heart Failure in Asia\r | viii | ||
Heart Transplant in Asia\r | viii | ||
Epidemiology of Heart Failure in Asia\r | viii | ||
Identifying Barriers and Practical Solutions to Conducting Site-Based Research in North America: Exploring Acute Heart Fail .\r | ix | ||
Hospitalized Heart Failure in the United States: Lessons Learned from Clinical Trial Populations\r | ix | ||
The Impact of Worsening Heart Failure in the United States\r | ix | ||
End-of-life Heart Failure Care in the United States\r | ix | ||
Epidemiology of Heart Failure in Europe\r | x | ||
Acute Heart Failure Syndromes in the Elderly: The European Perspective\r | x | ||
Characteristics of Intensive Care in Patients Hospitalized for Heart Failure in Europe\r | x | ||
HEART FAILURE CLINICS\r | xi | ||
FORTHCOMING ISSUES | xi | ||
January 2016 | xi | ||
April 2016 | xi | ||
RECENT ISSUES | xi | ||
July 2015 | xi | ||
April 2015 | xi | ||
Preface: Heart Failure: A Global Pandemic and Not Just a Disease of the West\r | xiii | ||
Socioeconomic Inequalities in Heart Failure | 507 | ||
Key points | 507 | ||
BACKGROUND | 507 | ||
SOCIOECONOMIC STATUS AND HEART FAILURE | 508 | ||
EDUCATIONAL LEVEL AND OCCUPATION | 508 | ||
HEALTH LITERACY AND HEART FAILURE | 509 | ||
BRIDGING THE GAPS IN SOCIOECONOMIC INEQUALITY | 510 | ||
FUTURE DIRECTIONS | 511 | ||
SUMMARY | 511 | ||
REFERENCES | 511 | ||
Heart Failure in Rural Communities | 515 | ||
Key points | 515 | ||
BACKGROUND | 515 | ||
EPIDEMIOLOGY | 516 | ||
ORGANIZATIONAL FACTORS IN RURAL HEALTH SYSTEMS | 517 | ||
Health System Policies | 517 | ||
Health Care Providers’ Adherence to Guidelines in the Rural Setting | 517 | ||
PATIENT-RELATED FACTORS IN RURAL COMMUNITIES | 518 | ||
ROLE OF INTERVENTIONS TO IMPROVE CHRONIC HEART FAILURE OUTCOMES IN RURAL COMMUNITIES | 518 | ||
Simplified Diagnostic Approach | 518 | ||
Telemedicine Support | 518 | ||
Patient Education | 519 | ||
Primary Health Care Provider Education and Training | 519 | ||
SUMMARY | 519 | ||
REFERENCES | 520 | ||
Inequalities in the Access to Advanced Therapy in Heart Failure | 523 | ||
Key points | 523 | ||
INTRODUCTION | 523 | ||
SOME DEFINITIONS | 523 | ||
Developing Countries | 523 | ||
The Chilean Health Care Model, as a Model of a Developing Country | 524 | ||
Defining Advanced Heart Failure | 524 | ||
GENERAL APPROACH TO ADVANCED THERAPIES AND INTRODUCTION TO THE PROBLEM OF INEQUALITIES | 524 | ||
Cardiac Resynchronization Therapy and Implantable Cardioverter-Defibrillators | 524 | ||
Mechanical Cardiac Support | 525 | ||
Heart Transplant | 526 | ||
OTHER FACTORS THAT MAKE DIFFICULT THE ACCESS TO ADVANCED THERAPIES | 526 | ||
Economic Issues | 526 | ||
Access to Health Care | 526 | ||
Low Number of Heart Failure Specialists | 527 | ||
SUMMARY | 527 | ||
REFERENCES | 527 | ||
Gaps and Resemblances in Current Heart Failure Guidelines | 529 | ||
Key points | 529 | ||
INTRODUCTION | 529 | ||
GRADING THE EVIDENCE AND CLASSIFYING THE RECOMMENDATIONS | 529 | ||
DEFINITIONS AND TYPES OF HEART FAILURE | 531 | ||
PHARMACOLOGIC TREATMENT IN HEART FAILURE | 532 | ||
Angiotensin I–Converting Enzyme Inhibitors | 532 | ||
Angiotensin Receptor Blockers | 532 | ||
Mineralocorticoid Receptor Antagonists | 533 | ||
β-Blockers | 534 | ||
Digoxin | 535 | ||
Hydralazine and Isosorbide | 535 | ||
Oral Anticoagulants | 536 | ||
NOVEL TREATMENTS | 536 | ||
Ivabradine | 536 | ||
Angiotensin Receptor–Neprilysin Inhibitors | 536 | ||
DEVICE RECOMMENDATIONS IN HEART FAILURE | 536 | ||
Cardiac Resynchronization Therapy | 536 | ||
Implantable Cardioverter-Defibrillators for Primary Prevention | 538 | ||
SUMMARY | 538 | ||
REFERENCES | 538 | ||
Prognostic Factors in Hospitalization for Heart Failure in Asia | 543 | ||
Key points | 543 | ||
INTRODUCTION | 543 | ||
PROGNOSTIC FACTORS OF MORTALITY AND MORBIDITY | 544 | ||
Age | 544 | ||
Hyponatremia | 545 | ||
Systolic Blood Pressure | 545 | ||
Renal Dysfunction | 546 | ||
Left Ventricular Function | 546 | ||
Ventricular Conduction Disturbance | 546 | ||
Anemia | 546 | ||
Evidence-based Medication Adherence | 547 | ||
Hospitalization | 547 | ||
EMERGING PROGNOSTIC FACTORS | 547 | ||
Hemoconcentration | 547 | ||
OTHER PROGNOSTIC FACTORS | 547 | ||
SUMMARY | 548 | ||
REFERENCES | 548 | ||
Biomarkers for Heart Failure in Asia | 551 | ||
Key points | 551 | ||
INTRODUCTION | 551 | ||
KEY PLAYERS | 551 | ||
JAPAN AND THE NATRIURETIC PEPTIDE STORY | 552 | ||
THE HONG KONG HERITAGE IN BIOMARKERS FOR HEART FAILURE | 553 | ||
NEW DEVELOPMENTS FROM ASIA IN BIOMARKERS FOR HEART FAILURE | 553 | ||
Peptide Biomarkers for Heart Failure in Asia | 553 | ||
News on Nonpeptide Markers from Asia | 555 | ||
Nucleic Acids as Biomarkers in Heart Failure | 555 | ||
Genotyping for Heart Failure in Asia | 556 | ||
Asia Is Organizing | 557 | ||
Markers When East Meets West | 557 | ||
REFERENCES | 558 | ||
Heart Transplant in Asia | 563 | ||
Key points | 563 | ||
INTRODUCTION | 563 | ||
HEART FAILURE IN ASIA | 563 | ||
Prevalence of Heart Failure | 563 | ||
Patients’ Characteristics of Heart Failure in Asia | 564 | ||
Advanced Heart Failure in Asia | 564 | ||
Heart Failure Management in Asia | 564 | ||
Heart Failure Outcome in Asia | 564 | ||
HEART TRANSPLANT IN ASIA | 564 | ||
History | 564 | ||
Incidence and Prevalence | 565 | ||
Recipient and Cause of End-Stage Heart Disease | 565 | ||
Screening for Donors | 565 | ||
Survival | 567 | ||
HEART TRANSPLANT IN SPECIAL SITUATIONS | 568 | ||
Rheumatic Heart Disease | 568 | ||
Elderly | 568 | ||
Hepatitis B Virus Infection | 568 | ||
POST–HEART TRANSPLANT CARE | 568 | ||
Immunosuppression and Rejection | 568 | ||
Endomyocardial Biopsy | 568 | ||
HEART TRANSPLANT COMPLICATION | 568 | ||
Primary Graft Failure | 568 | ||
Cardiac Allograft Vasculopathy | 568 | ||
Cardiac Arrhythmia | 568 | ||
Malignancy | 569 | ||
Infection | 569 | ||
Mechanical Circulatory Support Devices in Asia | 569 | ||
Barriers and Key to Success in Heart Transplant Program in Asia | 569 | ||
Law | 569 | ||
Ethical Issue | 569 | ||
Infrastructure | 569 | ||
Donor Shortage | 569 | ||
Limitation of Data | 570 | ||
Future | 570 | ||
SUMMARY | 570 | ||
REFERENCES | 570 | ||
Epidemiology of Heart Failure in Asia | 573 | ||
Key points | 573 | ||
INTRODUCTION | 573 | ||
IMPORTANT ISSUES FOR EPIDEMIOLOGIC COMPARISON | 573 | ||
Definitions of Heart Failure in Registries of Patients Hospitalized for Heart Failure | 573 | ||
Site Selection | 574 | ||
The Time Frame | 574 | ||
Ethnic Differences | 575 | ||
EPIDEMIOLOGIC COMPARISON OF PATIENTS HOSPITALIZED FOR HEART FAILURE IN ASIA | 575 | ||
Patient Characteristics | 575 | ||
Management | 575 | ||
Outcome | 577 | ||
SUMMARY | 578 | ||
REFERENCES | 578 | ||
Identifying Barriers and Practical Solutions to Conducting Site-Based Research in North America | 581 | ||
Key points | 581 | ||
INTRODUCTION | 582 | ||
BARRIER: POOR VISIBILITY OF CARDIOVASCULAR DISEASE AND CLINICAL TRIALS WITHIN THE INSTITUTION AND THE BROADER COMMUNITY | 582 | ||
BARRIER: INABILITY OF STUDY SPONSORS TO IDENTIFY SITES CAPABLE OF ENROLLING HIGH VOLUME AND QUALITY PATIENTS | 583 | ||
BARRIER: TIME-CONSUMING STUDY PROTOCOLS THAT DO NOT REFLECT THE DAY-TO-DAY REALITIES OF PATIENT CARE | 584 | ||
BARRIER: INADEQUATE INFRASTRUCTURE FOR RECRUITMENT OF PARTICIPANTS AND STUDY CONDUCT | 586 | ||
BARRIER: UNDERDEVELOPED RELATIONSHIPS BETWEEN CARDIOLOGISTS AND OTHER PHYSICIANS CARING FOR THE CARDIAC PATIENT | 587 | ||
BARRIER: MISALIGNMENT OF INCENTIVES BETWEEN PRINCIPLE INVESTIGATORS AND PARENT CLINICAL FACILITY | 587 | ||
BARRIER: LIMITED UPFRONT TRAINING AND ONGOING SUPPORT FOR STUDY COORDINATORS AND OTHER STAFF | 588 | ||
SUMMARY | 588 | ||
REFERENCES | 588 | ||
Hospitalized Heart Failure in the United States | 591 | ||
Key points | 591 | ||
UNITED STATES STUDY ENROLLMENT | 592 | ||
PATIENT CHARACTERISTICS | 593 | ||
LENGTH OF STAY AND READMISSION RISK | 596 | ||
THERAPY UTILIZATION | 596 | ||
CLINICAL OUTCOMES | 597 | ||
POTENTIAL FUTURE DIRECTIONS FOR UNITED STATES TRIALS | 598 | ||
SUMMARY | 599 | ||
REFERENCES | 600 | ||
The Impact of Worsening Heart Failure in the United States | 603 | ||
Key points | 603 | ||
INTRODUCTION AND DEFINITIONS | 603 | ||
ESTABLISHING A DEFINITION FOR WORSENING HEART FAILURE AS A CLINICAL TRIAL ENDPOINT | 604 | ||
INITIAL DESCRIPTIONS OF THE INCIDENCE OF WORSENING HEART FAILURE AND ASSOCIATED OUTCOMES | 605 | ||
WORSENING HEART FAILURE AS A TRIAL ENDPOINT | 605 | ||
ASSOCIATION OF WORSENING HEART FAILURE WITH CLINICAL OUTCOMES | 605 | ||
TREATMENT OF WORSENING HEART FAILURE | 611 | ||
PREDICTION OF WORSENING HEART FAILURE | 611 | ||
DEVELOPING THERAPEUTICS AND TREATMENT STRATEGIES THAT DECREASE WORSENING HEART FAILURE | 612 | ||
SUMMARY | 613 | ||
REFERENCES | 613 | ||
End-of-life Heart Failure Care in the United States | 615 | ||
Key points | 615 | ||
INTRODUCTION | 615 | ||
RESOURCE USE | 616 | ||
PREDICTING DEATH | 616 | ||
Hospitalized Setting | 616 | ||
Ambulatory Setting | 616 | ||
MANAGEMENT OPTIONS | 617 | ||
Prolonging Life | 617 | ||
Symptom Management | 618 | ||
PALLIATIVE CARE AND HOSPICE | 619 | ||
CHALLENGES AND SOLUTIONS | 619 | ||
SUMMARY | 620 | ||
REFERENCES | 620 | ||
Epidemiology of Heart Failure in Europe | 625 | ||
Key points | 625 | ||
INTRODUCTION | 625 | ||
PATIENTS HOSPITALIZED FOR ACUTE HEART FAILURE | 626 | ||
Italian Network on Heart Failure Outcome Registry Findings | 626 | ||
European Society of Cardiology Heart Failure Pilot Survey | 627 | ||
European Society of Cardiology Heart Failure Long-Term Registry | 629 | ||
AMBULATORY PATIENTS WITH CHRONIC HEART FAILURE | 632 | ||
Italian Network on Heart Failure Outcome Registry Findings | 632 | ||
European Society of Cardiology Heart Failure Pilot and Long-Term registries | 633 | ||
SUMMARY | 634 | ||
REFERENCES | 634 | ||
Acute Heart Failure Syndromes in the Elderly | 637 | ||
Key points | 637 | ||
INTRODUCTION | 637 | ||
CLINICAL PRESENTATION OF ELDERLY PATIENTS WITH ACUTE HEART FAILURE | 639 | ||
COMORBIDITIES | 640 | ||
MANAGEMENT OF ELDERLY PATIENTS WITH ACUTE HEART FAILURE | 640 | ||
OUTCOMES OF ELDERLY PATIENTS WITH ACUTE HEART FAILURE | 641 | ||
PREDICTORS OF CLINICAL OUTCOMES OF ELDERLY PATIENTS WITH ACUTE HEART FAILURE | 641 | ||
COMPARISON OF THE EUROPEAN AND NORTH AMERICAN EXPERIENCE IN ELDERLY WITH ACUTE HEART FAILURE | 643 | ||
SUMMARY AND FUTURE DIRECTIONS | 643 | ||
REFERENCES | 644 | ||
Characteristics of Intensive Care in Patients Hospitalized for Heart Failure in Europe | 647 | ||
Key points | 647 | ||
INTRODUCTION | 647 | ||
DATA SOURCE INFORMATION | 648 | ||
INTENSIVE CARE UNIT ADMISSION RATES | 648 | ||
BASELINE CHARACTERISTICS OF PATIENTS ADMITTED TO INTENSIVE CARE UNITS | 649 | ||
IN-HOSPITAL THERAPIES AND INVASIVE PROCEDURES | 650 | ||
INTENSIVE CARE UNIT OUTCOMES | 652 | ||
INTENSIVE CARE UNIT TRIAGE | 653 | ||
CLINICAL RESEARCH IN THE INTENSIVE CARE UNIT SETTING | 654 | ||
EUROPEAN PERSPECTIVES ON TRAINING AND EDUCATION IN CRITICAL CARE | 654 | ||
SUMMARY | 655 | ||
REFERENCES | 655 |