BOOK
Larsen's Human Embryology E-Book
Gary C. Schoenwolf | Steven B. Bleyl | Philip R. Brauer | Philippa H. Francis-West
(2014)
Additional Information
Book Details
Abstract
Larsen's Human Embryology works as a well-organized, straightforward guide to this highly complex subject, placing an emphasis on the clinical application of embryology and presenting it in an easily digestible manner. Ideal for visual students, this updated medical textbook includes a superior art program, brand-new online animations, and high-quality images throughout; clear descriptions and explanations of human embryonic development, based on all of the most up-to-date scientific discoveries and understanding, keep you abreast of the latest knowledge in the field.
- Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
- Take advantage of the most current advances in molecular biology and genetics.
- Review the material in a flexible manner that meets your specific needs thanks to a user-friendly design.
- Access high-yield content and quickly locate key information with help from newly condensed text and additional summary tables.
- Take advantage of key pedagogical features such as opening "Summary" boxes.
- Visualize complex concepts more clearly than before through a superior art program and outstanding clinical content and images throughout.
- Reinforce your understanding of the material and how it will relate to real-life scenarios with "Embryology in Practice" clinical closers added to each chapter.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| IFC | IFC | ||
| Larsen's Human\rEmbryology | iii | ||
| Copyright | iv | ||
| Dedication | v | ||
| Content Experts | vii | ||
| Preface | ix | ||
| Acknowledgments | x | ||
| Contents | xi | ||
| Video Contents | xv | ||
| INTRODUCTION | 1 | ||
| WHY STUDY HUMAN EMBRYOLOGY? | 2 | ||
| PERIODS OF HUMAN EMBRYOLOGY | 3 | ||
| PERIOD OF EGG AND EMBRYO: SUMMARY OF MAIN EVENTS | 5 | ||
| PHASES OF HUMAN EMBRYOLOGY | 5 | ||
| BODY AXES: UNDERSTANDING EMBRYONIC COORDINATES | 9 | ||
| WANT TO LEARN MORE? | 11 | ||
| Suggested Readings | 13 | ||
| Chapter 1 - Gametogenesis, Fertilization, and First Week | 14 | ||
| SUMMARY | 14 | ||
| PRIMORDIAL GERM CELLS | 16 | ||
| GAMETOGENESIS | 18 | ||
| SPERMATOGENESIS | 22 | ||
| OOGENESIS | 25 | ||
| OVULATION | 30 | ||
| MENSTRUAL CYCLE | 33 | ||
| FERTILIZATION | 33 | ||
| CLEAVAGE | 35 | ||
| END OF FIRST WEEK: INITIATING IMPLANTATION | 37 | ||
| Suggested Readings | 42 | ||
| Chapter 2 - Second Week: Becoming Bilaminar and Fully Implanting | 43 | ||
| SUMMARY | 43 | ||
| BECOMING FULLY IMPLANTED | 45 | ||
| EMBRYOBLAST REORGANIZES INTO EPIBLAST AND HYPOBLAST | 47 | ||
| DEVELOPMENT OF AMNIOTIC CAVITY | 47 | ||
| DEVELOPMENT OF YOLK SAC AND CHORIONIC CAVITY | 48 | ||
| UTEROPLACENTAL CIRCULATORY SYSTEM BEGINS TO DEVELOP DURING SECOND WEEK | 51 | ||
| Suggested Readings | 56 | ||
| Chapter 3 - Third Week: Becoming Trilaminar and Establishing Body Axes | 57 | ||
| SUMMARY | 57 | ||
| OVERVIEW OF GASTRULATION: FORMING THREE PRIMARY GERM LAYERS AND BODY AXES | 59 | ||
| SPECIFICS OF GASTRULATION: MOVING CELLS TO NEW LOCATIONS AND MAKING ORGAN RUDIMENTS THAT UNDERGO INDUCTIVE INTERACTIONS | 68 | ||
| FORMATION OF NEURAL PLATE | 77 | ||
| PRIMARY VERSUS SECONDARY BODY DEVELOPMENT | 80 | ||
| Suggested Readings | 81 | ||
| Chapter 4 - Fourth Week: Forming the Embryo | 82 | ||
| SUMMARY | 82 | ||
| TUBE-WITHIN-A-TUBE BODY PLAN ARISES THROUGH BODY FOLDING | 83 | ||
| NEURULATION: ESTABLISHING NEURAL TUBE, RUDIMENT OF CENTRAL NERVOUS SYSTEM | 87 | ||
| SECONDARY NEURULATION | 95 | ||
| CRANIAL-CAUDAL REGIONALIZATION OF NEURAL TUBE | 95 | ||
| NEURAL CREST CELLS | 96 | ||
| SOMITE DIFFERENTIATION: FORMING DERMAMYOTOME AND SCLEROTOME | 105 | ||
| Suggested Readings | 107 | ||
| Chapter 5 - Principles and Mechanisms of Morphogenesis and Dysmorphogenesis | 108 | ||
| SUMMARY | 108 | ||
| PRINCIPLES OF MORPHOGENESIS AND DYSMORPHOGENESIS | 108 | ||
| ANIMAL MODELS | 110 | ||
| USING ANIMAL MODELS TO PREDICT HUMAN RISK | 115 | ||
| EXPERIMENTAL TECHNIQUES | 115 | ||
| SIGNALING PATHWAYS | 122 | ||
| EMBRYONIC STEM CELLS AND CLONING | 131 | ||
| Suggested Readings | 132 | ||
| Chapter 6 - Fetal Development and the Fetus as a Patient | 133 | ||
| SUMMARY | 133 | ||
| DURING FETAL PERIOD, EMBRYONIC ORGAN SYSTEMS MATURE AND FETUS GROWS | 135 | ||
| DEVELOPMENT OF PLACENTA | 136 | ||
| DEVELOPMENT OF UMBILICAL CORD | 138 | ||
| EXCHANGE OF SUBSTANCES BETWEEN MATERNAL AND FETAL BLOOD IN PLACENTA | 138 | ||
| INTRAUTERINE GROWTH RESTRICTION | 143 | ||
| MATERNAL DIABETES AND OBESITY | 143 | ||
| PLACENTA PRODUCES SEVERAL IMPORTANT HORMONES | 143 | ||
| PRODUCTION AND RESORPTION OF AMNIOTIC FLUID | 144 | ||
| TWINNING | 144 | ||
| PRENATAL DIAGNOSIS ASSESSES HEALTH OF UNBORN | 146 | ||
| TREATING FETUS IN UTERO | 150 | ||
| FETAL CORD BLOOD AND STEM CELLS | 153 | ||
| PRETERM BIRTH | 153 | ||
| Suggested Readings | 154 | ||
| Chapter 7 - Development of the Skin and Its Derivatives | 155 | ||
| SUMMARY | 155 | ||
| DEVELOPMENT OF SKIN DERIVATIVES | 162 | ||
| DEVELOPMENT OF HAIR | 163 | ||
| DEVELOPMENT OF SEBACEOUS AND SWEAT GLANDS | 167 | ||
| DEVELOPMENT OF MAMMARY GLANDS | 167 | ||
| DEVELOPMENT OF NAILS | 169 | ||
| Suggested Readings | 171 | ||
| Chapter 8 - Development of the Musculoskeletal System | 172 | ||
| SUMMARY | 172 | ||
| TISSUE ORIGINS AND DIFFERENTIATION OF MUSCULOSKELETAL SYSTEM | 173 | ||
| SOMITES DIFFERENTIATE INTO SCLEROTOME AND DERMAMYOTOME | 175 | ||
| RESEGMENTATION OF SCLEROTOMES | 178 | ||
| MYOTOMES DEVELOP AT SEGMENTAL LEVELS | 185 | ||
| LONG BONE AND JOINT DEVELOPMENT | 187 | ||
| DEVELOPMENT OF LIMB MUSCLES | 191 | ||
| Suggested Readings | 196 | ||
| Chapter 9 - Development of the Central Nervous System | 197 | ||
| SUMMARY | 197 | ||
| STRUCTURAL DIVISIONS OF NERVOUS SYSTEM | 200 | ||
| FUNCTIONAL DIVISIONS OF NERVOUS SYSTEM | 200 | ||
| Primary Brain Vesicles Subdivide to Form Secondary Brain Vesicles | 200 | ||
| FORMATION OF BRAIN FLEXURES | 202 | ||
| CYTODIFFERENTIATION OF NEURAL TUBE | 204 | ||
| DIFFERENTIATION OF SPINAL CORD | 204 | ||
| DIFFERENTIATION OF BRAIN | 204 | ||
| GROWTH OF BRAIN | 231 | ||
| Suggested Readings | 233 | ||
| Chapter 10 - Development of the Peripheral Nervous System | 234 | ||
| SUMMARY | 234 | ||
| STRUCTURAL DIVISIONS OF NERVOUS SYSTEM | 236 | ||
| FUNCTIONAL DIVISIONS OF NERVOUS SYSTEM | 236 | ||
| ORIGIN OF PNS | 237 | ||
| DEVELOPMENT OF TRUNK PNS | 238 | ||
| DEVELOPMENT OF CRANIAL PNS | 247 | ||
| Suggested Readings | 249 | ||
| Chapter 11 - Development of the Respiratory System and Body Cavities | 251 | ||
| SUMMARY | 251 | ||
| DEVELOPMENT OF LUNGS AND RESPIRATORY TREE | 252 | ||
| PARTITIONING OF COELOM AND FORMATION OF DIAPHRAGM | 260 | ||
| Suggested Readings | 266 | ||
| Chapter 12 - Development of the Heart | 267 | ||
| SUMMARY | 267 | ||
| ESTABLISHING CARDIAC LINEAGE | 269 | ||
| FORMATION OF PRIMARY HEART TUBE | 271 | ||
| CARDIAC LOOPING | 276 | ||
| FORMATION OF PRIMITIVE BLOOD VESSELS ASSOCIATED WITH THE ENDOCARDIAL TUBE | 279 | ||
| COORDINATED REMODELING OF HEART TUBE AND PRIMITIVE VASCULATURE PRODUCES SYSTEMIC AND PULMONARY CIRCULATIONS | 280 | ||
| SEPTATION OF HEART | 283 | ||
| DEVELOPMENT OF PACEMAKER AND CONDUCTION SYSTEM | 295 | ||
| DEVELOPMENT OF EPICARDIUM AND CORONARY VASCULATURE | 296 | ||
| Suggested Readings | 303 | ||
| Chapter 13 - Development of the Vasculature | 304 | ||
| SUMMARY | 304 | ||
| FORMATION OF BLOOD AND VASCULATURE BEGINS EARLY IN THIRD WEEK | 306 | ||
| VASCULOGENESIS AND ANGIOGENESIS | 309 | ||
| ARTERIES VERSUS VEINS | 312 | ||
| Development of Aortic Arch Arteries | 314 | ||
| DORSAL AORTA DEVELOPS VENTRAL, LATERAL, AND POSTEROLATERAL BRANCHES | 320 | ||
| Primitive Embryonic Venous System is Divided into Vitelline, Umbilical, and Cardinal Systems | 327 | ||
| DEVELOPMENT OF LYMPHATIC SYSTEM | 334 | ||
| DRAMATIC CHANGES OCCUR IN CIRCULATORY SYSTEM AT BIRTH | 334 | ||
| Suggested Readings | 340 | ||
| Chapter 14 - Development of the Gastrointestinal Tract | 341 | ||
| SUMMARY | 341 | ||
| Body Folding | 343 | ||
| DORSAL MESENTERY INITIALLY SUSPENDS ABDOMINAL GUT TUBE | 343 | ||
| THREE REGIONS OF PRIMITIVE GUT | 345 | ||
| Development of Abdominal Foregut | 349 | ||
| SPLEEN DEVELOPMENT | 356 | ||
| VENTRAL MESENTERY DERIVATIVES | 356 | ||
| Midgut Development | 357 | ||
| CYTODIFFERENTIATION OF GUT ENDODERMAL EPITHELIUM | 364 | ||
| DEVELOPMENT OF OUTER INTESTINAL WALL AND ITS INNERVATION | 367 | ||
| Hindgut Development | 371 | ||
| Suggested Readings | 374 | ||
| Chapter 15 - Development of the Urinary System | 375 | ||
| SUMMARY | 375 | ||
| Three Nephric Systems Arise During Development | 376 | ||
| RELOCATION OF KIDNEYS | 386 | ||
| Contributions of Hindgut Endoderm to Urinary Tract | 387 | ||
| DEVELOPMENT OF SUPRARENAL GLAND | 389 | ||
| Suggested Readings | 393 | ||
| Chapter 16 - Development of the Reproductive System | 394 | ||
| SUMMARY | 394 | ||
| Reproductive System Arises with Urinary System | 396 | ||
| IN PRESENCE OF Y CHROMOSOME, MALE DEVELOPMENT OCCURS | 396 | ||
| IN ABSENCE OF Y CHROMOSOME, FEMALE DEVELOPMENT OCCURS | 408 | ||
| Development of External Genitalia | 415 | ||
| Suspension of Mesonephric-Gonadal Complex within Abdomen | 418 | ||
| DEVELOPMENT OF INGUINAL CANALS | 419 | ||
| DESCENT OF TESTES | 421 | ||
| OVARIES BECOME SUSPENDED IN BROAD LIGAMENT OF UTERUS AND ARE HELD HIGH IN ABDOMINAL CAVITY BY CRANIAL SUSPENSORY LIGAMENTS | 423 | ||
| Suggested Readings | 428 | ||
| Chapter 17 - Development of the Pharyngeal Apparatus and Face | 429 | ||
| SUMMARY | 429 | ||
| ORIGIN OF SKULL | 431 | ||
| Development of Pharyngeal Arches | 440 | ||
| Development of Face | 449 | ||
| DEVELOPMENT OF NASAL AND ORAL CAVITIES | 453 | ||
| DEVELOPMENT OF SINUSES | 457 | ||
| FATE OF PHARYNGEAL CLEFTS | 458 | ||
| PHARYNGEAL ARCHES GIVE RISE TO TONGUE | 458 | ||
| DEVELOPMENT OF THYROID GLAND | 461 | ||
| DEVELOPMENT OF PHARYNGEAL POUCHES | 462 | ||
| DEVELOPMENT OF SALIVARY GLANDS | 464 | ||
| DEVELOPMENT OF TEETH | 466 | ||
| Suggested Readings | 472 | ||
| Chapter 18 - Development of the Ears | 473 | ||
| SUMMARY | 473 | ||
| Ear Consists of Three Individual Components | 474 | ||
| DEVELOPMENT OF INNER EAR | 475 | ||
| DEVELOPMENT OF MIDDLE EAR | 485 | ||
| DEVELOPMENT OF EXTERNAL EAR | 485 | ||
| Suggested Readings | 487 | ||
| Chapter 19 - Development of the Eyes | 488 | ||
| SUMMARY | 488 | ||
| EYE ORIGINATES FROM SEVERAL EMBRYONIC TISSUES LAYERS | 489 | ||
| DEVELOPMENT OF OPTIC CUP AND LENS | 490 | ||
| DEVELOPMENT OF EYELIDS | 498 | ||
| Chapter 20 - Development of the Limbs | 501 | ||
| SUMMARY | 501 | ||
| Epithelial-Mesenchymal Interactions Control Limb Outgrowth | 503 | ||
| MORPHOGENESIS OF LIMB | 506 | ||
| TISSUE ORIGINS OF LIMB STRUCTURES | 519 | ||
| DIFFERENTIATION OF LIMB BONES | 519 | ||
| INNERVATION OF DEVELOPING LIMB | 519 | ||
| Figure Credits | 525 | ||
| Index | 533 | ||
| IBC | IBC |