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Book Details
Abstract
Inflammatory Bowel Disease is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Inflammatory Bowel Disease: Historical Perspective, Epidemiology and Risk Factors; Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy; Diagnostic Modalities for Inflammatory Bowel Disease: Radiologic Imaging; Medical Therapy for Inflammatory Bowel Disease; Crohn's Disease of the Foregut and Small Intestine; Crohn's Disease of the Colon, Rectum and Anus; Indications and Options for Surgery in Ulcerative Colitis; Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease; Extraintestinal Manifestations of Inflammatory Bowel Disease; Colorectal Neoplasia and Inflammatory Bowel Disease; Nutritional Support of the Inflammatory Bowel Disease Patient; Psychosocial Support of the Inflammatory Bowel Disease Patient; Genetics and Pathogenesis of Inflammatory Bowel Disease; and more!
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Inflammatory Bowel Disease\r | i | ||
| Copyright\r | ii | ||
| Contributors | iii | ||
| CONSULTING EDITOR | iii | ||
| EDITOR | iii | ||
| AUTHORS | iii | ||
| Contents | v | ||
| Foreword: Inflammatory Bowel Disease\r | v | ||
| Preface: Inflammatory Bowel Disease\r | v | ||
| Inflammatory Bowel Disease: Historical Perspective, Epidemiology, and Risk Factors\r | v | ||
| Diagnostic Modalities for Inflammatory Bowel Disease: Serologic Markers and Endoscopy\r | v | ||
| Imaging for Inflammatory Bowel Disease\r | v | ||
| Medical Therapy for Inflammatory Bowel Disease\r | vi | ||
| Crohn’s Disease of the Foregut\r | vi | ||
| Crohn’s Disease of the Colon, Rectum, and Anus\r | vi | ||
| Indications and Options for Surgery in Ulcerative Colitis\r | vi | ||
| Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease\r | vii | ||
| Extraintestinal Manifestations Associated with Inflammatory Bowel Disease\r | vii | ||
| Colorectal Neoplasia and Inflammatory Bowel Disease\r | vii | ||
| Nutritional Support of Patient with Inflammatory Bowel Disease\r | vii | ||
| Psychosocial Support of the Inflammatory Bowel Disease Patient \r | vii | ||
| SURGICAL CLINICS\rOF NORTH AMERICA\x0B | ix | ||
| FORTHCOMING ISSUES | ix | ||
| February 2016 | ix | ||
| April 2016 | ix | ||
| June 2016 | ix | ||
| RECENT ISSUES | ix | ||
| October 2015 | ix | ||
| August 2015 | ix | ||
| June 2015 | ix | ||
| April 2015 | ix | ||
| Foreword: Inflammatory Bowel Disease \r | xi | ||
| Preface: Inflammatory Bowel Disease \r | xiii | ||
| REFERENCES | xiv | ||
| Inflammatory Bowel Disease | 1105 | ||
| Key points | 1105 | ||
| INTRODUCTION | 1105 | ||
| HISTORICAL PERSPECTIVE | 1106 | ||
| Background | 1106 | ||
| Trends in Occurrence and Distribution | 1107 | ||
| Trends in Classification | 1107 | ||
| Trends in the Course of Disease | 1107 | ||
| Trends in Goals of Management | 1109 | ||
| EPIDEMIOLOGY | 1109 | ||
| Incidence | 1109 | ||
| Prevalence | 1109 | ||
| Distribution by Age | 1109 | ||
| Distribution by Gender | 1109 | ||
| Racial and Ethnic Disparity | 1110 | ||
| RISK FACTORS | 1110 | ||
| Cause and Pathogenesis | 1110 | ||
| Postulated Environmental Triggers | 1110 | ||
| Intestinal Immune Mechanism | 1110 | ||
| Genetic Predisposition | 1111 | ||
| Gut Flora | 1111 | ||
| Role of Diet | 1111 | ||
| Role of Mesenteric Fat and Obesity | 1111 | ||
| Role of Smoking | 1112 | ||
| Medications and Inflammatory Bowel Disease | 1112 | ||
| Infections and Inflammatory Bowel Disease | 1112 | ||
| Role of Immunization | 1112 | ||
| Hygiene Hypothesis | 1112 | ||
| Pregnancy, Breastfeeding, and Inflammatory Bowel Disease | 1113 | ||
| Role of Stress and Lifestyle in Inflammatory Bowel Disease | 1113 | ||
| Inflammatory Bowel Disease and Surgery | 1113 | ||
| Inflammatory Bowel Disease and Cancer | 1114 | ||
| Inflammatory Bowel Disease and Mortality | 1114 | ||
| CONCLUDING REMARKS | 1114 | ||
| REFERENCES | 1115 | ||
| Diagnostic Modalities for Inflammatory Bowel Disease | 1123 | ||
| Key points | 1123 | ||
| INTRODUCTION | 1123 | ||
| RELEVANT ANATOMY AND PATHOPHYSIOLOGY | 1124 | ||
| CLINICAL PRESENTATION | 1124 | ||
| SEROLOGIC MARKERS AS DIAGNOSTIC MODALITIES FOR INFLAMMATORY BOWEL DISEASE | 1124 | ||
| Atypical Perinuclear Antineutrophil Cytoplasmic Antibody | 1124 | ||
| Anti-Saccharimyces cerevisiae Antibody | 1127 | ||
| Antibodies to Escherichia coli Outer Membrane Porin | 1127 | ||
| Pseudomonas fluorescens–Associated Sequence I2 | 1128 | ||
| Flagellin CBir1/Fla-X/A4-Fla2 | 1128 | ||
| Serologic Panels | 1129 | ||
| ENDOSCOPIC DIAGNOSTIC MODALITIES | 1130 | ||
| Deep Enteroscopy | 1130 | ||
| Balloon-assisted enteroscopy | 1130 | ||
| Single-balloon enteroscopy | 1130 | ||
| Double-balloon enteroscopy | 1130 | ||
| Spiral enteroscopy | 1131 | ||
| Outcomes of Deep Enteroscopy | 1131 | ||
| Video Capsule Endoscopy | 1132 | ||
| Magnification Endoscopy and Chromoendoscopy (Dye-Based and Dyeless Chromoendoscopy) | 1132 | ||
| Confocal Laser Endomicroscopy | 1134 | ||
| Colon Capsule Endoscopy | 1134 | ||
| ENDOSCOPIC MONITORING OF DISEASE ACTIVITY | 1135 | ||
| SUMMARY | 1137 | ||
| REFERENCES | 1137 | ||
| Imaging for Inflammatory Bowel Disease | 1143 | ||
| Key points | 1143 | ||
| PLAIN RADIOGRAPHS | 1143 | ||
| Introduction | 1143 | ||
| Contrast Radiologic Studies | 1145 | ||
| Upper gastrointestinal series with small bowel follow through | 1145 | ||
| Double-contrast barium enema | 1145 | ||
| ABDOMINAL COMPUTED TOMOGRAPHIC AND COMPUTED TOMOGRAPHY ENTEROGRAPHY | 1146 | ||
| MRI | 1148 | ||
| Technique | 1148 | ||
| Indication for Use | 1149 | ||
| Limitations | 1151 | ||
| Future Direction | 1151 | ||
| ULTRASOUND | 1152 | ||
| Future Directions | 1152 | ||
| CAPSULE ENDOSCOPY | 1152 | ||
| Technique | 1153 | ||
| History | 1153 | ||
| Indication for Use | 1154 | ||
| Limitations | 1155 | ||
| Future Direction | 1155 | ||
| REFERENCES | 1155 | ||
| Medical Therapy for Inflammatory Bowel Disease | 1159 | ||
| Key points | 1159 | ||
| INTRODUCTION | 1159 | ||
| INFLAMMATORY BOWEL DISEASE MEDICATIONS | 1160 | ||
| 5-Aminosalicyclic Acid Compounds | 1160 | ||
| Action and metabolism | 1160 | ||
| Efficacy | 1161 | ||
| Safety | 1161 | ||
| IMMUNOMODULATOR THERAPY | 1162 | ||
| Thiopurines | 1162 | ||
| Action and metabolism | 1162 | ||
| Efficacy | 1163 | ||
| Side effects | 1163 | ||
| Methotrexate | 1163 | ||
| Action | 1163 | ||
| Crohn’s Disease of the Foregut | 1183 | ||
| Key points | 1183 | ||
| INTRODUCTION | 1183 | ||
| ESOPHAGEAL CROHN’S DISEASE | 1184 | ||
| Signs and Symptoms | 1185 | ||
| Treatment | 1185 | ||
| Strictures | 1186 | ||
| Fistulas | 1186 | ||
| GASTRODUODENAL CROHN’S DISEASE | 1186 | ||
| Signs and Symptoms | 1187 | ||
| Endoscopic Findings | 1187 | ||
| Treatment | 1187 | ||
| Medical Management | 1187 | ||
| Endoscopic Management | 1188 | ||
| Surgical Management | 1188 | ||
| Duodenal Obstruction | 1188 | ||
| Fistulas | 1190 | ||
| Malignancy | 1190 | ||
| SUMMARY | 1190 | ||
| REFERENCES | 1190 | ||
| Crohn's Disease of the Colon, Rectum, and Anus | 1195 | ||
| Key points | 1195 | ||
| PRESENTATIONS OF CROHN'S DISEASE | 1195 | ||
| Intra-Abdominal Abscess | 1195 | ||
| Abdominal Wall Abscesses | 1196 | ||
| Toxic Megacolon | 1196 | ||
| Bleeding | 1197 | ||
| Obstruction Because of Stricture | 1198 | ||
| OPERATIONS AND TECHNIQUES FOR CROHN'S DISEASE OF THE COLON AND RECTUM | 1198 | ||
| Segmental Resection | 1198 | ||
| Total Abdominal Colectomy with Ileorectal Anastomosis | 1199 | ||
| Restorative Proctocolectomy | 1200 | ||
| Total Abdominal Colectomy with Ileostomy Without Proctectomy | 1200 | ||
| Management of the Rectal Stump | 1200 | ||
| Secondary Proctectomy | 1201 | ||
| Total Proctocolectomy with Ileostomy | 1202 | ||
| Abdominoperineal Resection for Distal Crohn's Disease | 1202 | ||
| MANAGEMENT OF SPECIFIC COMPLICATIONS AFTER SURGERY FOR CROHN'S DISEASE | 1202 | ||
| Perineal Wound after Proctectomy | 1202 | ||
| High Ileostomy Output after Total Proctocolectomy with End Ileostomy | 1203 | ||
| Perianal Crohn's Disease | 1203 | ||
| Anal Fistulae | 1204 | ||
| Anal Stenosis and Strictures | 1204 | ||
| Fecal Diversion for Perianal Crohn's Disease | 1205 | ||
| SUMMARY | 1206 | ||
| ACKNOWLEDGMENTS | 1206 | ||
| REFERENCES | 1207 | ||
| Indications and Options for Surgery in Ulcerative Colitis | 1211 | ||
| Key points | 1211 | ||
| INTRODUCTION | 1211 | ||
| INDICATIONS FOR SURGERY IN PATIENTS WITH ULCERATIVE COLITIS | 1212 | ||
| Cancer Risk | 1212 | ||
| Intractability | 1212 | ||
| Emergency Situations | 1212 | ||
| EMERGENT SURGICAL TECHNIQUES | 1213 | ||
| Emergent Open Total Abdominal Colectomy with End Ileostomy | 1213 | ||
| Preoperative planning | 1213 | ||
| Prep and positioning | 1213 | ||
| Intra-abdominal access | 1213 | ||
| Right colon mobilization | 1213 | ||
| Pitfalls | 1213 | ||
| Omental preservation | 1214 | ||
| Left colon mobilization | 1214 | ||
| Splenic flexure mobilization | 1215 | ||
| Pitfalls | 1215 | ||
| Bowel transection | 1216 | ||
| Division of the vascular pedicles | 1216 | ||
| Pitfalls | 1216 | ||
| Ileostomy creation | 1217 | ||
| Pitfalls | 1217 | ||
| Procedure completion | 1217 | ||
| Additional Considerations | 1217 | ||
| Fate of preserved rectum | 1217 | ||
| Laparoscopic versus open approach | 1217 | ||
| Poor rectal tissue integrity | 1218 | ||
| Indeterminate colitis | 1218 | ||
| ELECTIVE SURGICAL TECHNIQUES | 1218 | ||
| Total Proctocolectomy with End Ileostomy | 1218 | ||
| Rectal dissection | 1218 | ||
| Pitfalls | 1219 | ||
| Anorectal dissection | 1219 | ||
| Intersphincteric proctectomy | 1220 | ||
| Extrasphincteric proctectomy | 1221 | ||
| End ileostomy creation | 1221 | ||
| Procedure completion | 1221 | ||
| Additional Considerations | 1222 | ||
| Long-term complications | 1222 | ||
| Delayed intersphincteric proctectomy | 1222 | ||
| Total Proctocolectomy with Ileal Pouch–Anal Anastomosis | 1222 | ||
| Preoperative considerations | 1222 | ||
| Staged procedures | 1222 | ||
| Separation of distal colon and rectum | 1222 | ||
| Mobilization of distal ileum | 1223 | ||
| Formation of J pouch | 1223 | ||
| Further mobilization if the pouch does not reach | 1224 | ||
| Formation of anal anastomosis | 1225 | ||
| Diverting loop ileostomy creation | 1225 | ||
| Procedure completion | 1225 | ||
| Additional Considerations | 1226 | ||
| Laparoscopic versus open approach | 1226 | ||
| Surveillance | 1226 | ||
| Long-term outcomes | 1226 | ||
| S-pouch function | 1226 | ||
| Total Proctocolectomy and Ileal Pouch–Anal Anastomosis with Mucosectomy and Hand-sewn Anastomosis | 1227 | ||
| Perineal dissection | 1227 | ||
| Hand-sewn anastomosis | 1227 | ||
| Ostomy creation | 1227 | ||
| Additional Considerations | 1227 | ||
| Hand-sewn versus double-stapled technique | 1227 | ||
| Ileal pouch–anal anastomosis in patients with rectal cancer | 1228 | ||
| Surveillance | 1228 | ||
| Elective Total Abdominal Colectomy with Ileoproctostomy | 1229 | ||
| Ileorectal anastomosis | 1229 | ||
| Pitfalls | 1229 | ||
| Additional Considerations | 1229 | ||
| Persistent proctitis | 1229 | ||
| Rectal cancer risk | 1229 | ||
| Elective Kock and Barnett Continent Ileostomies | 1229 | ||
| SUMMARY | 1230 | ||
| REFERENCES | 1230 | ||
| Challenges in the Medical and Surgical Management of Chronic Inflammatory Bowel Disease | 1233 | ||
| Key points | 1233 | ||
| INTRODUCTION | 1233 | ||
| INTESTINAL FISTULA | 1234 | ||
| SHORT BOWEL SYNDROME | 1236 | ||
| POUCH COMPLICATIONS | 1239 | ||
| DEEP VENOUS THROMBOSIS | 1240 | ||
| SUMMARY | 1241 | ||
| REFERENCES | 1241 | ||
| Extraintestinal Manifestations Associated with Inflammatory Bowel Disease | 1245 | ||
| Key points | 1245 | ||
| INTRODUCTION | 1245 | ||
| MUSCULOSKELETAL MANIFESTATIONS | 1247 | ||
| Peripheral Arthropathies | 1247 | ||
| Axial Arthropathies | 1248 | ||
| DERMATOLOGIC MANIFESTATIONS | 1248 | ||
| Erythema Nodosum | 1248 | ||
| Pyoderma Gangrenosum | 1249 | ||
| Aphthous Ulcers | 1249 | ||
| Sweet Syndrome | 1250 | ||
| OCULAR MANIFESTATIONS | 1250 | ||
| Episcleritis and Scleritis | 1251 | ||
| Uveitis | 1251 | ||
| HEPATOBILIARY MANIFESTATIONS | 1252 | ||
| Primary Sclerosing Cholangitis | 1252 | ||
| Cholelithiasis | 1253 | ||
| Portal Vein Thrombosis | 1253 | ||
| RENAL | 1253 | ||
| PULMONARY | 1254 | ||
| SUMMARY | 1254 | ||
| REFERENCES | 1254 | ||
| Colorectal Neoplasia and Inflammatory Bowel Disease | 1261 | ||
| Key points | 1261 | ||
| INTRODUCTION | 1261 | ||
| MECHANISM OF ACTION OF INCREASED RISK | 1262 | ||
| ULCERATIVE COLITIS AND COLORECTAL CANCER | 1262 | ||
| SURVEILLANCE | 1262 | ||
| MANAGEMENT OF DYSPLASIA | 1263 | ||
| DYSPLASIA-ASSOCIATED LESION OR MASS | 1264 | ||
| NEOPLASIA FOLLOWING PROCTOCOLECTOMY WITH ILEAL POUCH-ANAL ANASTOMOSIS | 1264 | ||
| CROHN'S DISEASE | 1266 | ||
| CANCER IN A FISTULA | 1266 | ||
| SUMMARY | 1266 | ||
| REFERENCES | 1267 | ||
| Nutritional Support of Patient with Inflammatory Bowel Disease | 1271 | ||
| Key points | 1271 | ||
| INTRODUCTION | 1271 | ||
| EFFECT OF INFLAMMATORY BOWEL DISEASE ON DIET, NUTRITION, AND METABOLISM | 1272 | ||
| Dietary Intake in Patients with Inflammatory Bowel Disease | 1272 | ||
| Specific Nutrient Deficiencies in Inflammatory Bowel Disease | 1273 | ||
| Microbial Alterations in Inflammatory Bowel Disease | 1273 | ||
| Pediatric Patients with Inflammatory Bowel Disease: A Special Patient Population | 1274 | ||
| DIAGNOSIS AND TREATMENT OF MALNUTRITION IN INFLAMMATORY BOWEL DISEASE | 1274 | ||
| Nutritional Assessment | 1274 | ||
| Nutritional Therapy | 1275 | ||
| PERIOPERATIVE CONSIDERATIONS | 1275 | ||
| SUMMARY | 1276 | ||
| REFERENCES | 1276 | ||
| Psychosocial Support of the Inflammatory Bowel Disease Patient | 1281 | ||
| Key points | 1281 | ||
| INTRODUCTION | 1281 | ||
| PSYCHIATRIC DISORDERS IN INFLAMMATORY BOWEL DISEASE | 1282 | ||
| PATHOPSYCHOLOGY OF DEPRESSION AND ANXIETY DISORDERS IN INFLAMMATORY BOWEL DISEASE | 1282 | ||
| SCREENING FOR PSYCHIATRIC DISORDERS IN INFLAMMATORY BOWEL DISEASE | 1283 | ||
| PHARMACOLOGIC TREATMENTS | 1284 | ||
| NONPHARMACOLOGIC PSYCHOTHERAPY | 1285 | ||
| HEALTH-RELATED QUALITY OF LIFE | 1286 | ||
| DETERMINANTS OF HEALTH-RELATED QUALITY OF LIFE IN INFLAMMATORY BOWEL DISEASE | 1287 | ||
| COPING WITH INFLAMMATORY BOWEL DISEASE | 1288 | ||
| IMPROVING QUALITY OF LIFE IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE | 1289 | ||
| SUMMARY | 1289 | ||
| REFERENCES | 1289 | ||
| Index | 1295 |