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Book Details
Abstract
Part of the highly regarded Diagnostic Pathology series, this updated volume is a visually stunning, easy-to-use reference covering all aspects of common and rare renal diseases and their variants. Outstanding images—including gross and microscopic pathology, a wide range of stains, and detailed medical illustrations—make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. Written by leading pathologists, this second edition presents an up-to-date, concise presentation of major pathological, clinical, pathophysiological, and genetic information for over 240 diagnoses.
- High-quality, carefully annotated images highlight critical information, including difficult issues of grading and staging and diagnostic dilemmas not covered in depth in other texts
- Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index
- Thoroughly updated content throughout with a particular emphasis on practical information that directly assists in making and supporting a diagnosis
- Over 25 new chapters with information on major advances in nephropathology/nephrology that have occurred since the first edition, especially in the classification of MPGN/complement-related diseases, lupus nephritis, transplant pathology, and newly recognized immunologic and genetic diseases such as ciliopathies, tubulointerstitial nephritis, and glomerulopathies
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
Diagnostic Pathology: Kidney Diseases | iii | ||
Copyright Page | iv | ||
Table of Contents | xvi | ||
Dedications | v | ||
Contributing Authors | vi | ||
Image Contributors | ix | ||
Preface | xi | ||
Acknowledgments | xiii | ||
Sections | xv | ||
SECTION 1:\rIntroduction | 3 | ||
Chapter 1.\rIntroduction to Renal Pathology | 4 | ||
VALUE OF RENAL BIOPSY | 4 | ||
INDICATIONS FOR RENAL BIOPSY | 4 | ||
BIOPSY TECHNIQUE AND SAFETY | 4 | ||
PROCESSING OF TISSUE | 4 | ||
SYSTEMATIC APPROACH | 5 | ||
ISSUES IN INTERPRETATION | 5 | ||
REPORTING RECOMMENDATIONS | 5 | ||
DEFINITIONS FOR GLOMERULI | 6 | ||
DEFINITIONS FOR TUBULES | 7 | ||
DEFINITIONS FOR INTERSTITIUM | 8 | ||
DEFINITIONS FOR VESSELS | 8 | ||
SELECTED REFERENCES | 8 | ||
Chapter 2.\rNormal Kidney Structure | 24 | ||
TERMINOLOGY | 24 | ||
MACROSCOPIC | 24 | ||
MICROSCOPIC | 25 | ||
SELECTED REFERENCES | 27 | ||
Chapter 3.\rNormal Kidney Development | 36 | ||
TERMINOLOGY | 36 | ||
STAGES OF KIDNEY DEVELOPMENT | 36 | ||
MAJOR COMPONENTS OF DEVELOPING\rMETANEPHROS, ORIGIN, AND DERIVATIVES | 36 | ||
STEPS IN METANEPHRIC KIDNEY\rDEVELOPMENT | 37 | ||
FINAL POSITION OF KIDNEYS | 37 | ||
GENES IMPORTANT IN KIDNEY\rDEVELOPMENT | 38 | ||
CELLULAR PROCESSES IN KIDNEY\rDEVELOPMENT | 38 | ||
SELECTED REFERENCES | 38 | ||
SECTION 2:\rGlomerular Diseases | 46 | ||
Chapter 4.\rMinimal Change Disease | 48 | ||
TERMINOLOGY | 49 | ||
ETIOLOGY/PATHOGENESIS | 49 | ||
CLINICAL ISSUES | 49 | ||
MACROSCOPIC | 50 | ||
MICROSCOPIC | 50 | ||
ANCILLARY TESTS | 50 | ||
DIFFERENTIAL DIAGNOSIS | 51 | ||
DIAGNOSTIC CHECKLIST | 51 | ||
SELECTED REFERENCES | 51 | ||
Chapter 5.\rDrug-Induced Minimal Change Disease | 56 | ||
TERMINOLOGY | 57 | ||
ETIOLOGY/PATHOGENESIS | 57 | ||
CLINICAL ISSUES | 57 | ||
MICROSCOPIC | 57 | ||
ANCILLARY TESTS | 57 | ||
DIFFERENTIAL DIAGNOSIS | 57 | ||
DIAGNOSTIC CHECKLIST | 57 | ||
SELECTED REFERENCES | 57 | ||
Chapter 6.\rEtiologic Classification of Focal Segmental Glomerulosclerosis | 58 | ||
Chapter 7.\rHistologic Classification of Focal Segmental Glomerulosclerosis | 60 | ||
TERMINOLOGY | 60 | ||
CLASSIFICATION SYSTEMS | 60 | ||
EPIDEMIOLOGY | 60 | ||
ETIOLOGY/PATHOGENESIS | 61 | ||
CLINICAL IMPLICATIONS | 61 | ||
MACROSCOPIC | 61 | ||
MICROSCOPIC | 61 | ||
ANCILLARY TESTS | 62 | ||
DIFFERENTIAL DIAGNOSIS | 62 | ||
DIAGNOSTIC CHECKLIST | 62 | ||
SELECTED REFERENCES | 62 | ||
Chapter 8.\rFocal Segmental Glomerulosclerosis, Primary | 64 | ||
TERMINOLOGY | 65 | ||
ETIOLOGY/PATHOGENESIS | 65 | ||
CLINICAL ISSUES | 65 | ||
MICROSCOPIC | 65 | ||
ANCILLARY TESTS | 66 | ||
DIFFERENTIAL DIAGNOSIS | 66 | ||
DIAGNOSTIC CHECKLIST | 66 | ||
SELECTED REFERENCES | 66 | ||
Chapter 9.\rFocal Segmental Glomerulosclerosis, Adaptive (Secondary) | 72 | ||
TERMINOLOGY | 73 | ||
ETIOLOGY/PATHOGENESIS | 73 | ||
CLINICAL ISSUES | 73 | ||
MICROSCOPIC | 74 | ||
ANCILLARY TESTS | 74 | ||
DIFFERENTIAL DIAGNOSIS | 74 | ||
DIAGNOSTIC CHECKLIST | 74 | ||
SELECTED REFERENCES | 74 | ||
Chapter 10.\rCollapsing Glomerulopathy | 78 | ||
TERMINOLOGY | 79 | ||
ETIOLOGY/PATHOGENESIS | 79 | ||
CLINICAL ISSUES | 79 | ||
MICROSCOPIC | 79 | ||
ANCILLARY TESTS | 80 | ||
DIFFERENTIAL DIAGNOSIS | 80 | ||
SELECTED REFERENCES | 80 | ||
Chapter 11.\rBisphosphonate-Induced Collapsing Glomerulopathy | 88 | ||
TERMINOLOGY | 89 | ||
ETIOLOGY/PATHOGENESIS | 89 | ||
CLINICAL ISSUES | 89 | ||
MICROSCOPIC | 89 | ||
ANCILLARY TESTS | 89 | ||
DIFFERENTIAL DIAGNOSIS | 89 | ||
DIAGNOSTIC CHECKLIST | 89 | ||
SELECTED REFERENCES | 89 | ||
Chapter 12.\rEtiologic Classification of Membranous Glomerulonephritis | 90 | ||
Chapter 13.\rMembranous Glomerulonephritis, Primary | 92 | ||
TERMINOLOGY | 93 | ||
ETIOLOGY/PATHOGENESIS | 93 | ||
CLINICAL ISSUES | 93 | ||
MICROSCOPIC | 93 | ||
ANCILLARY TESTS | 94 | ||
DIFFERENTIAL DIAGNOSIS | 94 | ||
DIAGNOSTIC CHECKLIST | 94 | ||
SELECTED REFERENCES | 94 | ||
Chapter 14.\rMembranous Glomerulonephritis, Secondary | 98 | ||
TERMINOLOGY | 99 | ||
ETIOLOGY/PATHOGENESIS | 99 | ||
CLINICAL ISSUES | 99 | ||
MICROSCOPIC | 99 | ||
ANCILLARY TESTS | 99 | ||
DIFFERENTIAL DIAGNOSIS | 99 | ||
DIAGNOSTIC CHECKLIST | 99 | ||
SELECTED REFERENCES | 99 | ||
Chapter 15.\rMembranous Glomerulonephritis With Anti-TBM Antibodies | 102 | ||
TERMINOLOGY | 103 | ||
ETIOLOGY/PATHOGENESIS | 103 | ||
CLINICAL ISSUES | 103 | ||
MICROSCOPIC | 103 | ||
ANCILLARY TESTS | 103 | ||
DIFFERENTIAL DIAGNOSIS | 103 | ||
DIAGNOSTIC CHECKLIST | 103 | ||
SELECTED REFERENCES | 103 | ||
Chapter 16.\rClassification of MPGN and Complement-Related Diseases | 104 | ||
TERMINOLOGY | 104 | ||
C3 GLOMERULOPATHIES | 105 | ||
IDIOPATHIC MPGN WITH IMMUNE COMPLEX\rDEPOSITION | 105 | ||
SELECTED REFERENCES | 105 | ||
Chapter 17.\rDense Deposit Disease | 108 | ||
TERMINOLOGY | 109 | ||
ETIOLOGY/PATHOGENESIS | 109 | ||
CLINICAL ISSUES | 109 | ||
MICROSCOPIC | 109 | ||
ANCILLARY TESTS | 110 | ||
DIFFERENTIAL DIAGNOSIS | 110 | ||
DIAGNOSTIC CHECKLIST | 110 | ||
SELECTED REFERENCES | 110 | ||
Chapter 18.\rC3 Glomerulonephritis | 114 | ||
TERMINOLOGY | 115 | ||
ETIOLOGY/PATHOGENESIS | 115 | ||
CLINICAL ISSUES | 115 | ||
MICROSCOPIC | 115 | ||
ANCILLARY TESTS | 116 | ||
DIFFERENTIAL DIAGNOSIS | 116 | ||
DIAGNOSTIC CHECKLIST | 116 | ||
SELECTED REFERENCES | 116 | ||
Chapter 19.\rMembranoproliferative Glomerulonephritis With Immune Complexes | 120 | ||
TERMINOLOGY | 121 | ||
ETIOLOGY/PATHOGENESIS | 121 | ||
CLINICAL ISSUES | 121 | ||
MACROSCOPIC | 121 | ||
MICROSCOPIC | 122 | ||
ANCILLARY TESTS | 122 | ||
DIFFERENTIAL DIAGNOSIS | 122 | ||
DIAGNOSTIC CHECKLIST | 123 | ||
SELECTED REFERENCES | 123 | ||
Chapter 20.\rIgA Nephropathy | 128 | ||
TERMINOLOGY | 129 | ||
ETIOLOGY/PATHOGENESIS | 129 | ||
CLINICAL ISSUES | 129 | ||
MICROSCOPIC | 130 | ||
ANCILLARY TESTS | 130 | ||
DIFFERENTIAL DIAGNOSIS | 130 | ||
DIAGNOSTIC CHECKLIST | 131 | ||
GRADING | 131 | ||
SELECTED REFERENCES | 131 | ||
Chapter 21.\rHenoch-Schönlein Purpura | 142 | ||
TERMINOLOGY | 143 | ||
ETIOLOGY/PATHOGENESIS | 143 | ||
CLINICAL ISSUES | 143 | ||
MICROSCOPIC | 144 | ||
ANCILLARY TESTS | 144 | ||
DIFFERENTIAL DIAGNOSIS | 144 | ||
DIAGNOSTIC CHECKLIST | 144 | ||
SELECTED REFERENCES | 144 | ||
Chapter 22.\rSystemic Lupus Erythematosus | 148 | ||
TERMINOLOGY | 149 | ||
ETIOLOGY/PATHOGENESIS | 149 | ||
CLINICAL ISSUES | 149 | ||
MICROSCOPIC | 150 | ||
ANCILLARY TESTS | 151 | ||
DIFFERENTIAL DIAGNOSIS | 151 | ||
DIAGNOSTIC CHECKLIST | 151 | ||
GRADING | 152 | ||
SELECTED REFERENCES | 152 | ||
Chapter 23.\rMixed Connective Tissue Disease | 166 | ||
TERMINOLOGY | 167 | ||
ETIOLOGY/PATHOGENESIS | 167 | ||
CLINICAL ISSUES | 167 | ||
MICROSCOPIC | 167 | ||
ANCILLARY TESTS | 167 | ||
DIFFERENTIAL DIAGNOSIS | 167 | ||
DIAGNOSTIC CHECKLIST | 167 | ||
SELECTED REFERENCES | 167 | ||
Chapter 24.\rRheumatoid Arthritis | 168 | ||
TERMINOLOGY | 169 | ||
ETIOLOGY/PATHOGENESIS | 169 | ||
CLINICAL ISSUES | 169 | ||
MICROSCOPIC | 169 | ||
ANCILLARY TESTS | 170 | ||
DIFFERENTIAL DIAGNOSIS | 170 | ||
SELECTED REFERENCES | 170 | ||
Chapter 25.\rMixed Cryoglobulinemic Glomerulonephritis | 174 | ||
TERMINOLOGY | 175 | ||
ETIOLOGY/PATHOGENESIS | 175 | ||
CLINICAL ISSUES | 175 | ||
MICROSCOPIC | 175 | ||
ANCILLARY TESTS | 176 | ||
DIFFERENTIAL DIAGNOSIS | 176 | ||
DIAGNOSTIC CHECKLIST | 176 | ||
SELECTED REFERENCES | 176 | ||
Chapter 26.\rAnti-GBM Glomerulonephritis | 180 | ||
TERMINOLOGY | 181 | ||
ETIOLOGY/PATHOGENESIS | 181 | ||
CLINICAL ISSUES | 181 | ||
MACROSCOPIC | 181 | ||
MICROSCOPIC | 182 | ||
ANCILLARY TESTS | 182 | ||
DIFFERENTIAL DIAGNOSIS | 182 | ||
DIAGNOSTIC CHECKLIST | 182 | ||
SELECTED REFERENCES | 182 | ||
Chapter 27.\rAtypical Anti-GBM Nephritis | 188 | ||
TERMINOLOGY | 189 | ||
ETIOLOGY/PATHOGENESIS | 189 | ||
CLINICAL ISSUES | 189 | ||
MICROSCOPIC | 189 | ||
ANCILLARY TESTS | 189 | ||
DIFFERENTIAL DIAGNOSIS | 189 | ||
SELECTED REFERENCES | 189 | ||
Chapter 28.\rIntroduction to Diseases With Monoclonal Immunoglobulin Deposits | 192 | ||
ETIOLOGY/PATHOGENESIS | 192 | ||
APPROACH | 192 | ||
SELECTED REFERENCES | 193 | ||
Chapter 29.\rMonoclonal Immunoglobulin Deposition Disease | 196 | ||
TERMINOLOGY | 197 | ||
ETIOLOGY/PATHOGENESIS | 197 | ||
CLINICAL ISSUES | 197 | ||
MICROSCOPIC | 197 | ||
ANCILLARY TESTS | 197 | ||
DIFFERENTIAL DIAGNOSIS | 198 | ||
DIAGNOSTIC CHECKLIST | 198 | ||
SELECTED REFERENCES | 198 | ||
Chapter 30.\rProliferative Glomerulonephritis With Monoclonal IgG Deposits | 204 | ||
TERMINOLOGY | 205 | ||
ETIOLOGY/PATHOGENESIS | 205 | ||
CLINICAL ISSUES | 205 | ||
MICROSCOPIC | 205 | ||
ANCILLARY TESTS | 205 | ||
DIFFERENTIAL DIAGNOSIS | 205 | ||
SELECTED REFERENCES | 205 | ||
Chapter 31.\rMembranous Glomerulonephritis With Masked IgG Kappa Deposits | 208 | ||
TERMINOLOGY | 209 | ||
ETIOLOGY/PATHOGENESIS | 209 | ||
CLINICAL ISSUES | 209 | ||
MICROSCOPIC | 209 | ||
ANCILLARY TESTS | 209 | ||
DIFFERENTIAL DIAGNOSIS | 209 | ||
SELECTED REFERENCES | 209 | ||
Chapter 32.\rType I Cryoglobulinemic Glomerulonephritis | 212 | ||
TERMINOLOGY | 213 | ||
ETIOLOGY/PATHOGENESIS | 213 | ||
CLINICAL ISSUES | 213 | ||
MICROSCOPIC | 213 | ||
ANCILLARY TESTS | 213 | ||
DIFFERENTIAL DIAGNOSIS | 213 | ||
DIAGNOSTIC CHECKLIST | 213 | ||
SELECTED REFERENCES | 213 | ||
Chapter 33.\rWaldenström Macroglobulinemia | 216 | ||
TERMINOLOGY | 217 | ||
ETIOLOGY/PATHOGENESIS | 217 | ||
CLINICAL ISSUES | 217 | ||
MICROSCOPIC | 217 | ||
ANCILLARY TESTS | 217 | ||
DIFFERENTIAL DIAGNOSIS | 217 | ||
DIAGNOSTIC CHECKLIST | 217 | ||
SELECTED REFERENCES | 217 | ||
Chapter 34.\rLight Chain Cast Nephropathy | 218 | ||
TERMINOLOGY | 219 | ||
ETIOLOGY/PATHOGENESIS | 219 | ||
CLINICAL ISSUES | 219 | ||
MICROSCOPIC | 219 | ||
ANCILLARY TESTS | 219 | ||
DIFFERENTIAL DIAGNOSIS | 219 | ||
DIAGNOSTIC CHECKLIST | 219 | ||
SELECTED REFERENCES | 219 | ||
Chapter 35.\rLight Chain Proximal Tubulopathy With Crystals | 224 | ||
TERMINOLOGY | 225 | ||
ETIOLOGY/PATHOGENESIS | 225 | ||
CLINICAL ISSUES | 225 | ||
MICROSCOPIC | 225 | ||
ANCILLARY TESTS | 225 | ||
DIFFERENTIAL DIAGNOSIS | 225 | ||
SELECTED REFERENCES | 225 | ||
Chapter 36.\rProximal Tubulopathy Without Crystals | 228 | ||
TERMINOLOGY | 229 | ||
ETIOLOGY/PATHOGENESIS | 229 | ||
CLINICAL ISSUES | 229 | ||
MICROSCOPIC | 229 | ||
ANCILLARY TESTS | 229 | ||
DIFFERENTIAL DIAGNOSIS | 229 | ||
SELECTED REFERENCES | 229 | ||
Chapter 37.\rAmyloidosis Classification | 232 | ||
TERMINOLOGY | 232 | ||
EPIDEMIOLOGY | 232 | ||
ETIOLOGY/PATHOGENESIS | 232 | ||
CLINICAL IMPLICATIONS | 232 | ||
MACROSCOPIC | 233 | ||
MICROSCOPIC | 233 | ||
ANCILLARY TESTS FOR AMYLOID DETECTION | 234 | ||
SELECTED REFERENCES | 234 | ||
Chapter 38.\rAL/AH Amyloidosis | 238 | ||
TERMINOLOGY | 239 | ||
ETIOLOGY/PATHOGENESIS | 239 | ||
CLINICAL ISSUES | 239 | ||
IMAGING | 239 | ||
MICROSCOPIC | 240 | ||
ANCILLARY TESTS | 240 | ||
DIFFERENTIAL DIAGNOSIS | 240 | ||
DIAGNOSTIC CHECKLIST | 240 | ||
SELECTED REFERENCES | 240 | ||
Chapter 39.\rAA Amyloidosis | 244 | ||
TERMINOLOGY | 245 | ||
ETIOLOGY/PATHOGENESIS | 245 | ||
CLINICAL ISSUES | 245 | ||
MICROSCOPIC | 246 | ||
ANCILLARY TESTS | 246 | ||
DIFFERENTIAL DIAGNOSIS | 246 | ||
SELECTED REFERENCES | 246 | ||
Chapter 40.\rALECT2 Amyloidosis | 248 | ||
TERMINOLOGY | 249 | ||
ETIOLOGY/PATHOGENESIS | 249 | ||
CLINICAL ISSUES | 249 | ||
MICROSCOPIC | 249 | ||
ANCILLARY TESTS | 249 | ||
DIFFERENTIAL DIAGNOSIS | 249 | ||
SELECTED REFERENCES | 249 | ||
Chapter 41.\rAFib Amyloidosis | 250 | ||
TERMINOLOGY | 251 | ||
ETIOLOGY/PATHOGENESIS | 251 | ||
CLINICAL ISSUES | 251 | ||
MICROSCOPIC | 251 | ||
ANCILLARY TESTS | 251 | ||
DIFFERENTIAL DIAGNOSIS | 251 | ||
SELECTED REFERENCES | 251 | ||
Chapter 42.\rAApoAI/II Amyloidosis | 252 | ||
TERMINOLOGY | 253 | ||
ETIOLOGY/PATHOGENESIS | 253 | ||
CLINICAL ISSUES | 253 | ||
MICROSCOPIC | 253 | ||
ANCILLARY TESTS | 253 | ||
DIFFERENTIAL DIAGNOSIS | 253 | ||
SELECTED REFERENCES | 253 | ||
Chapter 43.\rATTR Amyloidosis | 254 | ||
TERMINOLOGY | 255 | ||
ETIOLOGY/PATHOGENESIS | 255 | ||
CLINICAL ISSUES | 255 | ||
MICROSCOPIC | 256 | ||
ANCILLARY TESTS | 256 | ||
DIFFERENTIAL DIAGNOSIS | 256 | ||
DIAGNOSTIC CHECKLIST | 256 | ||
SELECTED REFERENCES | 256 | ||
Chapter 44.\rDiseases With Organized Deposits | 258 | ||
INTRODUCTION | 258 | ||
CHARACTERIZATION OF ORGANIZED\rDEPOSITS | 258 | ||
SELECTED REFERENCES | 259 | ||
Chapter 45.\rFibrillary Glomerulopathy | 262 | ||
TERMINOLOGY | 263 | ||
ETIOLOGY/PATHOGENESIS | 263 | ||
CLINICAL ISSUES | 263 | ||
MICROSCOPIC | 263 | ||
ANCILLARY TESTS | 263 | ||
DIFFERENTIAL DIAGNOSIS | 263 | ||
SELECTED REFERENCES | 263 | ||
Chapter 46.\rImmunotactoid Glomerulopathy | 266 | ||
TERMINOLOGY | 267 | ||
ETIOLOGY/PATHOGENESIS | 267 | ||
CLINICAL ISSUES | 267 | ||
MICROSCOPIC | 267 | ||
ANCILLARY TESTS | 267 | ||
DIFFERENTIAL DIAGNOSIS | 267 | ||
DIAGNOSTIC CHECKLIST | 267 | ||
SELECTED REFERENCES | 267 | ||
Chapter 47.\rFibronectin Glomerulopathy | 270 | ||
TERMINOLOGY | 271 | ||
ETIOLOGY/PATHOGENESIS | 271 | ||
CLINICAL ISSUES | 271 | ||
MICROSCOPIC | 271 | ||
ANCILLARY TESTS | 271 | ||
DIFFERENTIAL DIAGNOSIS | 272 | ||
DIAGNOSTIC CHECKLIST | 272 | ||
SELECTED REFERENCES | 272 | ||
Chapter 48.\rDiabetic Nephropathy | 274 | ||
TERMINOLOGY | 275 | ||
ETIOLOGY/PATHOGENESIS | 275 | ||
CLINICAL ISSUES | 275 | ||
MACROSCOPIC | 276 | ||
MICROSCOPIC | 276 | ||
ANCILLARY TESTS | 277 | ||
DIFFERENTIAL DIAGNOSIS | 277 | ||
DIAGNOSTIC CHECKLIST | 278 | ||
SELECTED REFERENCES | 278 | ||
Chapter 49.\rIdiopathic Nodular Glomerulopathy | 284 | ||
TERMINOLOGY | 285 | ||
ETIOLOGY/PATHOGENESIS | 285 | ||
CLINICAL ISSUES | 285 | ||
MICROSCOPIC | 285 | ||
ANCILLARY TESTS | 285 | ||
DIFFERENTIAL DIAGNOSIS | 286 | ||
DIAGNOSTIC CHECKLIST | 286 | ||
SELECTED REFERENCES | 286 | ||
Chapter 50.\rOverview of Infection-Related Glomerular Disease | 290 | ||
TERMINOLOGY | 290 | ||
EPIDEMIOLOGY | 290 | ||
ETIOLOGY/PATHOGENESIS | 290 | ||
CLINICAL IMPLICATIONS | 291 | ||
MACROSCOPIC | 291 | ||
MICROSCOPIC | 291 | ||
DIAGNOSIS | 291 | ||
SELECTED REFERENCES | 291 | ||
Chapter 51.\rAcute Poststreptococcal Glomerulonephritis | 294 | ||
TERMINOLOGY | 295 | ||
ETIOLOGY/PATHOGENESIS | 295 | ||
CLINICAL ISSUES | 295 | ||
MACROSCOPIC | 295 | ||
MICROSCOPIC | 295 | ||
ANCILLARY TESTS | 296 | ||
DIFFERENTIAL DIAGNOSIS | 296 | ||
DIAGNOSTIC CHECKLIST | 296 | ||
SELECTED REFERENCES | 296 | ||
Chapter 52.\rAcute Postinfectious Glomerulonephritis, Nonstreptococcal | 302 | ||
TERMINOLOGY | 303 | ||
ETIOLOGY/PATHOGENESIS | 303 | ||
CLINICAL ISSUES | 303 | ||
MICROSCOPIC | 303 | ||
ANCILLARY TESTS | 304 | ||
DIFFERENTIAL DIAGNOSIS | 304 | ||
DIAGNOSTIC CHECKLIST | 304 | ||
SELECTED REFERENCES | 304 | ||
Chapter 53.\rIgA Acute Glomerulonephritis Associated With Staphylococcus aureus | 308 | ||
TERMINOLOGY | 309 | ||
ETIOLOGY/PATHOGENESIS | 309 | ||
CLINICAL ISSUES | 309 | ||
MICROSCOPIC | 309 | ||
ANCILLARY TESTS | 309 | ||
DIFFERENTIAL DIAGNOSIS | 309 | ||
DIAGNOSTIC CHECKLIST | 309 | ||
SELECTED REFERENCES | 309 | ||
Chapter 54.\rGlomerulonephritis of Chronic Infection Including Shunt Nephritis | 312 | ||
TERMINOLOGY | 313 | ||
ETIOLOGY/PATHOGENESIS | 313 | ||
CLINICAL ISSUES | 313 | ||
MICROSCOPIC | 313 | ||
ANCILLARY TESTS | 313 | ||
DIFFERENTIAL DIAGNOSIS | 313 | ||
SELECTED REFERENCES | 313 | ||
Chapter 55.\rEndocarditis | 314 | ||
TERMINOLOGY | 315 | ||
ETIOLOGY/PATHOGENESIS | 315 | ||
CLINICAL ISSUES | 315 | ||
MACROSCOPIC | 315 | ||
MICROSCOPIC | 315 | ||
ANCILLARY TESTS | 316 | ||
DIFFERENTIAL DIAGNOSIS | 316 | ||
DIAGNOSTIC CHECKLIST | 316 | ||
SELECTED REFERENCES | 316 | ||
Chapter 56.\rSyphilis | 318 | ||
TERMINOLOGY | 319 | ||
ETIOLOGY/PATHOGENESIS | 319 | ||
CLINICAL ISSUES | 319 | ||
MICROSCOPIC | 319 | ||
ANCILLARY TESTS | 319 | ||
DIFFERENTIAL DIAGNOSIS | 319 | ||
DIAGNOSTIC CHECKLIST | 319 | ||
SELECTED REFERENCES | 319 | ||
Chapter 57.\rLyme Disease | 320 | ||
TERMINOLOGY | 321 | ||
ETIOLOGY/PATHOGENESIS | 321 | ||
CLINICAL ISSUES | 321 | ||
MICROSCOPIC | 321 | ||
ANCILLARY TESTS | 321 | ||
DIFFERENTIAL DIAGNOSIS | 321 | ||
SELECTED REFERENCES | 321 | ||
Chapter 58.\rHepatitis B Virus | 322 | ||
TERMINOLOGY | 323 | ||
ETIOLOGY/PATHOGENESIS | 323 | ||
CLINICAL ISSUES | 323 | ||
MICROSCOPIC | 323 | ||
ANCILLARY TESTS | 323 | ||
DIFFERENTIAL DIAGNOSIS | 324 | ||
DIAGNOSTIC CHECKLIST | 324 | ||
SELECTED REFERENCES | 324 | ||
Chapter 59.\rHepatitis C Virus | 326 | ||
TERMINOLOGY | 327 | ||
ETIOLOGY/PATHOGENESIS | 327 | ||
CLINICAL ISSUES | 327 | ||
MICROSCOPIC | 327 | ||
DIFFERENTIAL DIAGNOSIS | 327 | ||
DIAGNOSTIC CHECKLIST | 327 | ||
SELECTED REFERENCES | 327 | ||
Chapter 60.\rHIV-Associated Nephropathy | 330 | ||
TERMINOLOGY | 331 | ||
ETIOLOGY/PATHOGENESIS | 331 | ||
CLINICAL ISSUES | 331 | ||
IMAGING | 331 | ||
MACROSCOPIC | 331 | ||
MICROSCOPIC | 331 | ||
ANCILLARY TESTS | 332 | ||
DIFFERENTIAL DIAGNOSIS | 332 | ||
SELECTED REFERENCES | 332 | ||
Chapter 61.\rMiscellaneous HIV-Associated Renal Diseases | 336 | ||
TERMINOLOGY | 336 | ||
HIV-ASSOCIATED LUPUS-LIKE\rGLOMERULONEPHRITIS | 336 | ||
IgA NEPHROPATHY | 337 | ||
HIV IMMUNE COMPLEX KIDNEY DISEASE | 337 | ||
THROMBOTIC MICROANGIOPATHY | 337 | ||
OTHER IMMUNE COMPLEX DISEASES | 338 | ||
TUBULOINTERSTITIAL DISEASE | 338 | ||
RENAL NEOPLASMS | 339 | ||
DIAGNOSTIC CHECKLIST | 339 | ||
SELECTED REFERENCES | 339 | ||
Chapter 62.\rSchistosomiasis | 342 | ||
TERMINOLOGY | 343 | ||
ETIOLOGY/PATHOGENESIS | 343 | ||
CLINICAL ISSUES | 343 | ||
MICROSCOPIC | 343 | ||
ANCILLARY TESTS | 343 | ||
DIFFERENTIAL DIAGNOSIS | 343 | ||
SELECTED REFERENCES | 343 | ||
Chapter 63.\rFilariasis | 344 | ||
TERMINOLOGY | 345 | ||
ETIOLOGY/PATHOGENESIS | 345 | ||
CLINICAL ISSUES | 345 | ||
MICROSCOPIC | 345 | ||
ANCILLARY TESTS | 345 | ||
DIFFERENTIAL DIAGNOSIS | 345 | ||
SELECTED REFERENCES | 345 | ||
Chapter 64.\rLeishmaniasis | 346 | ||
TERMINOLOGY | 347 | ||
ETIOLOGY/PATHOGENESIS | 347 | ||
CLINICAL ISSUES | 347 | ||
MICROSCOPIC | 347 | ||
ANCILLARY TESTS | 347 | ||
DIFFERENTIAL DIAGNOSIS | 347 | ||
DIAGNOSTIC CHECKLIST | 347 | ||
SELECTED REFERENCES | 347 | ||
Chapter 65.\rOverview and Classification of Genetic Diseases of the Glomerulus | 348 | ||
TERMINOLOGY | 348 | ||
CLASSIFICATION CATEGORIES | 348 | ||
ETIOLOGY/PATHOGENESIS | 349 | ||
CLINICAL IMPLICATIONS | 349 | ||
MICROSCOPIC | 349 | ||
SELECTED REFERENCES | 349 | ||
Chapter 66.\rAlport Syndrome | 352 | ||
TERMINOLOGY | 353 | ||
ETIOLOGY/PATHOGENESIS | 353 | ||
CLINICAL ISSUES | 353 | ||
MICROSCOPIC | 354 | ||
ANCILLARY TESTS | 354 | ||
DIFFERENTIAL DIAGNOSIS | 355 | ||
DIAGNOSTIC CHECKLIST | 355 | ||
SELECTED REFERENCES | 355 | ||
Chapter 67.\rThin Basement Membrane Disease | 364 | ||
TERMINOLOGY | 365 | ||
ETIOLOGY/PATHOGENESIS | 365 | ||
CLINICAL ISSUES | 365 | ||
MICROSCOPIC | 365 | ||
ANCILLARY TESTS | 365 | ||
DIFFERENTIAL DIAGNOSIS | 365 | ||
SELECTED REFERENCES | 365 | ||
Chapter 68.\rPierson Syndrome | 366 | ||
TERMINOLOGY | 367 | ||
ETIOLOGY/PATHOGENESIS | 367 | ||
CLINICAL ISSUES | 367 | ||
IMAGING | 367 | ||
MICROSCOPIC | 367 | ||
ANCILLARY TESTS | 367 | ||
DIFFERENTIAL DIAGNOSIS | 367 | ||
SELECTED REFERENCES | 367 | ||
Chapter 69.\rCongenital Nephrotic Syndrome of the Finnish Type | 370 | ||
TERMINOLOGY | 371 | ||
ETIOLOGY/PATHOGENESIS | 371 | ||
CLINICAL ISSUES | 371 | ||
IMAGING | 371 | ||
MACROSCOPIC | 371 | ||
MICROSCOPIC | 371 | ||
ANCILLARY TESTS | 372 | ||
DIFFERENTIAL DIAGNOSIS | 372 | ||
DIAGNOSTIC CHECKLIST | 372 | ||
SELECTED REFERENCES | 372 | ||
Chapter 70.\rPodocin Deficiency | 376 | ||
TERMINOLOGY | 377 | ||
ETIOLOGY/PATHOGENESIS | 377 | ||
CLINICAL ISSUES | 377 | ||
MICROSCOPIC | 377 | ||
ANCILLARY TESTS | 377 | ||
DIFFERENTIAL DIAGNOSIS | 377 | ||
DIAGNOSTIC CHECKLIST | 377 | ||
SELECTED REFERENCES | 377 | ||
Chapter 71.\rAlpha-Actinin-4 Deficiency | 378 | ||
TERMINOLOGY | 379 | ||
ETIOLOGY/PATHOGENESIS | 379 | ||
CLINICAL ISSUES | 379 | ||
MICROSCOPIC | 379 | ||
ANCILLARY TESTS | 379 | ||
DIFFERENTIAL DIAGNOSIS | 379 | ||
SELECTED REFERENCES | 379 | ||
Chapter 72.\rAutosomal Dominant FSGS Due to INF2 Mutations | 380 | ||
TERMINOLOGY | 381 | ||
ETIOLOGY/PATHOGENESIS | 381 | ||
CLINICAL ISSUES | 381 | ||
MICROSCOPIC | 381 | ||
ANCILLARY TESTS | 381 | ||
DIFFERENTIAL DIAGNOSIS | 381 | ||
DIAGNOSTIC CHECKLIST | 381 | ||
SELECTED REFERENCES | 381 | ||
Chapter 73.\rDiffuse Mesangial Sclerosis | 382 | ||
TERMINOLOGY | 383 | ||
ETIOLOGY/PATHOGENESIS | 383 | ||
CLINICAL ISSUES | 383 | ||
MICROSCOPIC | 383 | ||
ANCILLARY TESTS | 383 | ||
DIFFERENTIAL DIAGNOSIS | 383 | ||
DIAGNOSTIC CHECKLIST | 383 | ||
SELECTED REFERENCES | 383 | ||
Chapter 74.\rDenys-Drash Syndrome | 386 | ||
TERMINOLOGY | 387 | ||
ETIOLOGY/PATHOGENESIS | 387 | ||
CLINICAL ISSUES | 387 | ||
MICROSCOPIC | 387 | ||
ANCILLARY TESTS | 387 | ||
DIFFERENTIAL DIAGNOSIS | 387 | ||
DIAGNOSTIC CHECKLIST | 387 | ||
SELECTED REFERENCES | 387 | ||
Chapter 75.\rFrasier Syndrome | 392 | ||
TERMINOLOGY | 393 | ||
ETIOLOGY/PATHOGENESIS | 393 | ||
CLINICAL ISSUES | 393 | ||
MICROSCOPIC | 393 | ||
ANCILLARY TESTS | 393 | ||
DIFFERENTIAL DIAGNOSIS | 393 | ||
SELECTED REFERENCES | 393 | ||
Chapter 76.\rAPOL1-Related Glomerular Disease | 396 | ||
TERMINOLOGY | 397 | ||
ETIOLOGY/PATHOGENESIS | 397 | ||
CLINICAL ISSUES | 397 | ||
MICROSCOPIC | 397 | ||
DIFFERENTIAL DIAGNOSIS | 397 | ||
SELECTED REFERENCES | 397 | ||
Chapter 77.\rLecithin-Cholesterol Acyltransferase Deficiency | 400 | ||
TERMINOLOGY | 401 | ||
ETIOLOGY/PATHOGENESIS | 401 | ||
CLINICAL ISSUES | 401 | ||
MICROSCOPIC | 401 | ||
ANCILLARY TESTS | 401 | ||
DIFFERENTIAL DIAGNOSIS | 401 | ||
SELECTED REFERENCES | 401 | ||
Chapter 78.\rAPOE Lipoprotein Glomerulopathy | 404 | ||
TERMINOLOGY | 405 | ||
ETIOLOGY/PATHOGENESIS | 405 | ||
CLINICAL ISSUES | 405 | ||
MICROSCOPIC | 405 | ||
ANCILLARY TESTS | 405 | ||
DIFFERENTIAL DIAGNOSIS | 405 | ||
SELECTED REFERENCES | 405 | ||
Chapter 79.\rType III Collagen Glomerulopathy | 406 | ||
TERMINOLOGY | 407 | ||
ETIOLOGY/PATHOGENESIS | 407 | ||
CLINICAL ISSUES | 407 | ||
MICROSCOPIC | 407 | ||
ANCILLARY TESTS | 408 | ||
DIFFERENTIAL DIAGNOSIS | 408 | ||
DIAGNOSTIC CHECKLIST | 408 | ||
SELECTED REFERENCES | 408 | ||
Chapter 80.\rGalloway-Mowat Syndrome | 410 | ||
TERMINOLOGY | 411 | ||
ETIOLOGY/PATHOGENESIS | 411 | ||
CLINICAL ISSUES | 411 | ||
MACROSCOPIC | 411 | ||
MICROSCOPIC | 411 | ||
DIFFERENTIAL DIAGNOSIS | 411 | ||
DIAGNOSTIC CHECKLIST | 411 | ||
SELECTED REFERENCES | 411 | ||
Chapter 81.\rFabry Disease | 416 | ||
TERMINOLOGY | 417 | ||
ETIOLOGY/PATHOGENESIS | 417 | ||
CLINICAL ISSUES | 417 | ||
MACROSCOPIC | 418 | ||
MICROSCOPIC | 418 | ||
ANCILLARY TESTS | 418 | ||
DIFFERENTIAL DIAGNOSIS | 419 | ||
DIAGNOSTIC CHECKLIST | 419 | ||
SELECTED REFERENCES | 419 | ||
Chapter 82.\rGaucher Glomerulopathy | 424 | ||
TERMINOLOGY | 425 | ||
ETIOLOGY/PATHOGENESIS | 425 | ||
CLINICAL ISSUES | 425 | ||
MICROSCOPIC | 425 | ||
ANCILLARY TESTS | 425 | ||
DIFFERENTIAL DIAGNOSIS | 425 | ||
SELECTED REFERENCES | 425 | ||
Chapter 83.\rI-Cell Disease (Mucolipidosis II) | 426 | ||
TERMINOLOGY | 427 | ||
ETIOLOGY/PATHOGENESIS | 427 | ||
CLINICAL ISSUES | 427 | ||
IMAGING | 427 | ||
MICROSCOPIC | 427 | ||
ANCILLARY TESTS | 427 | ||
DIFFERENTIAL DIAGNOSIS | 427 | ||
DIAGNOSTIC CHECKLIST | 427 | ||
SELECTED REFERENCES | 427 | ||
Chapter 84.\rAlagille Syndrome | 430 | ||
TERMINOLOGY | 431 | ||
ETIOLOGY/PATHOGENESIS | 431 | ||
CLINICAL ISSUES | 431 | ||
MACROSCOPIC | 431 | ||
MICROSCOPIC | 431 | ||
ANCILLARY TESTS | 431 | ||
DIFFERENTIAL DIAGNOSIS | 431 | ||
SELECTED REFERENCES | 431 | ||
Chapter 85.\rGlomerulopathy of Hereditary Multiple Exostoses | 432 | ||
TERMINOLOGY | 433 | ||
ETIOLOGY/PATHOGENESIS | 433 | ||
CLINICAL ISSUES | 433 | ||
MICROSCOPIC | 433 | ||
ANCILLARY TESTS | 433 | ||
DIFFERENTIAL DIAGNOSIS | 433 | ||
SELECTED REFERENCES | 433 | ||
Chapter 86.\rType III Hyperlipoproteinemia | 434 | ||
TERMINOLOGY | 435 | ||
ETIOLOGY/PATHOGENESIS | 435 | ||
CLINICAL ISSUES | 435 | ||
MICROSCOPIC | 435 | ||
ANCILLARY TESTS | 435 | ||
DIFFERENTIAL DIAGNOSIS | 435 | ||
DIAGNOSTIC CHECKLIST | 435 | ||
SELECTED REFERENCES | 435 | ||
Chapter 87.\rNail-Patella Syndrome | 436 | ||
TERMINOLOGY | 437 | ||
ETIOLOGY/PATHOGENESIS | 437 | ||
CLINICAL ISSUES | 437 | ||
MICROSCOPIC | 437 | ||
ANCILLARY TESTS | 437 | ||
DIFFERENTIAL DIAGNOSIS | 437 | ||
DIAGNOSTIC CHECKLIST | 437 | ||
SELECTED REFERENCES | 437 | ||
Chapter 88.\rC1q Nephropathy | 438 | ||
TERMINOLOGY | 439 | ||
ETIOLOGY/PATHOGENESIS | 439 | ||
CLINICAL ISSUES | 439 | ||
MICROSCOPIC | 439 | ||
ANCILLARY TESTS | 440 | ||
DIFFERENTIAL DIAGNOSIS | 440 | ||
DIAGNOSTIC CHECKLIST | 440 | ||
SELECTED REFERENCES | 440 | ||
Chapter 89.\rIgM Nephropathy | 444 | ||
TERMINOLOGY | 445 | ||
ETIOLOGY/PATHOGENESIS | 445 | ||
CLINICAL ISSUES | 445 | ||
MICROSCOPIC | 445 | ||
ANCILLARY TESTS | 445 | ||
DIFFERENTIAL DIAGNOSIS | 445 | ||
DIAGNOSTIC CHECKLIST | 445 | ||
SELECTED REFERENCES | 445 | ||
Chapter 90.\rHepatic Glomerulosclerosis and IgA Deposition | 446 | ||
TERMINOLOGY | 447 | ||
ETIOLOGY/PATHOGENESIS | 447 | ||
CLINICAL ISSUES | 447 | ||
MICROSCOPIC | 447 | ||
ANCILLARY TESTS | 447 | ||
DIFFERENTIAL DIAGNOSIS | 447 | ||
SELECTED REFERENCES | 447 | ||
Chapter 91.\rChloroquine Toxicity | 448 | ||
TERMINOLOGY | 449 | ||
ETIOLOGY/PATHOGENESIS | 449 | ||
CLINICAL ISSUES | 449 | ||
MICROSCOPIC | 449 | ||
ANCILLARY TESTS | 449 | ||
DIFFERENTIAL DIAGNOSIS | 449 | ||
DIAGNOSTIC CHECKLIST | 449 | ||
SELECTED REFERENCES | 449 | ||
Chapter 92.\rIntravascular Large B-Cell Lymphoma | 450 | ||
TERMINOLOGY | 451 | ||
CLINICAL ISSUES | 451 | ||
MACROSCOPIC | 451 | ||
MICROSCOPIC | 451 | ||
ANCILLARY TESTS | 451 | ||
DIFFERENTIAL DIAGNOSIS | 451 | ||
SELECTED REFERENCES | 451 | ||
SECTION 3:\rVascular Diseases | 452 | ||
Chapter 93.\rOverview and Classification of Systemic Vasculitides | 454 | ||
TERMINOLOGY | 454 | ||
CHAPEL HILL CONSENSUS CONFERENCE NOMENCLATURE OF SYSTEMIC\rVASCULITIDES (1994 AND REVISED 2012) | 455 | ||
OTHER CLASSIFICATION SYSTEMS | 456 | ||
EPIDEMIOLOGY | 456 | ||
ETIOLOGY/PATHOGENESIS | 456 | ||
CLINICAL IMPLICATIONS | 456 | ||
MACROSCOPIC | 457 | ||
MICROSCOPIC | 457 | ||
CONDITIONS THAT MIMIC VASCULITIS | 457 | ||
SELECTED REFERENCES | 457 | ||
Chapter 94.\rANCA-Related Glomerulonephritis | 464 | ||
TERMINOLOGY | 465 | ||
ETIOLOGY/PATHOGENESIS | 465 | ||
CLINICAL ISSUES | 465 | ||
MACROSCOPIC | 466 | ||
MICROSCOPIC | 466 | ||
ANCILLARY TESTS | 466 | ||
DIFFERENTIAL DIAGNOSIS | 466 | ||
DIAGNOSTIC CHECKLIST | 467 | ||
SELECTED REFERENCES | 467 | ||
Chapter 95.\rMicroscopic Polyangiitis | 470 | ||
TERMINOLOGY | 471 | ||
ETIOLOGY/PATHOGENESIS | 471 | ||
CLINICAL ISSUES | 471 | ||
MACROSCOPIC | 472 | ||
MICROSCOPIC | 472 | ||
ANCILLARY TESTS | 472 | ||
DIFFERENTIAL DIAGNOSIS | 472 | ||
SELECTED REFERENCES | 472 | ||
Chapter 96.\rGranulomatosis With Polyangiitis (Wegener) | 478 | ||
TERMINOLOGY | 479 | ||
ETIOLOGY/PATHOGENESIS | 479 | ||
CLINICAL ISSUES | 479 | ||
IMAGING | 480 | ||
MACROSCOPIC | 480 | ||
MICROSCOPIC | 480 | ||
ANCILLARY TESTS | 481 | ||
DIFFERENTIAL DIAGNOSIS | 481 | ||
DIAGNOSTIC CHECKLIST | 481 | ||
SELECTED REFERENCES | 481 | ||
Chapter 97.\rEosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) | 488 | ||
TERMINOLOGY | 489 | ||
ETIOLOGY/PATHOGENESIS | 489 | ||
CLINICAL ISSUES | 489 | ||
MICROSCOPIC | 490 | ||
ANCILLARY TESTS | 490 | ||
DIFFERENTIAL DIAGNOSIS | 490 | ||
DIAGNOSTIC CHECKLIST | 491 | ||
SELECTED REFERENCES | 491 | ||
Chapter 98.\rDrug-Induced ANCA Vasculitis | 494 | ||
TERMINOLOGY | 495 | ||
ETIOLOGY/PATHOGENESIS | 495 | ||
CLINICAL ISSUES | 495 | ||
MICROSCOPIC | 495 | ||
ANCILLARY TESTS | 496 | ||
DIFFERENTIAL DIAGNOSIS | 496 | ||
DIAGNOSTIC CHECKLIST | 496 | ||
SELECTED REFERENCES | 496 | ||
Chapter 99.\rPolyarteritis Nodosa | 498 | ||
TERMINOLOGY | 499 | ||
ETIOLOGY/PATHOGENESIS | 499 | ||
CLINICAL ISSUES | 499 | ||
IMAGING | 500 | ||
MICROSCOPIC | 500 | ||
DIFFERENTIAL DIAGNOSIS | 500 | ||
DIAGNOSTIC CHECKLIST | 500 | ||
SELECTED REFERENCES | 500 | ||
Chapter 100.\rKawasaki Disease | 504 | ||
TERMINOLOGY | 505 | ||
ETIOLOGY/PATHOGENESIS | 505 | ||
CLINICAL ISSUES | 505 | ||
IMAGING | 506 | ||
MICROSCOPIC | 506 | ||
DIFFERENTIAL DIAGNOSIS | 506 | ||
SELECTED REFERENCES | 506 | ||
Chapter 101.\rGiant Cell Arteritis | 508 | ||
TERMINOLOGY | 509 | ||
ETIOLOGY/PATHOGENESIS | 509 | ||
CLINICAL ISSUES | 509 | ||
IMAGING | 509 | ||
MICROSCOPIC | 510 | ||
DIFFERENTIAL DIAGNOSIS | 510 | ||
DIAGNOSTIC CHECKLIST | 510 | ||
SELECTED REFERENCES | 510 | ||
Chapter 102.\rTakayasu Arteritis | 512 | ||
TERMINOLOGY | 513 | ||
ETIOLOGY/PATHOGENESIS | 513 | ||
CLINICAL ISSUES | 513 | ||
IMAGING | 513 | ||
MACROSCOPIC | 514 | ||
MICROSCOPIC | 514 | ||
DIFFERENTIAL DIAGNOSIS | 514 | ||
SELECTED REFERENCES | 514 | ||
Chapter 103.\rHypocomplementemic Urticarial Vasculitis (Anti-C1q Vasculitis) | 516 | ||
TERMINOLOGY | 517 | ||
ETIOLOGY/PATHOGENESIS | 517 | ||
CLINICAL ISSUES | 517 | ||
MICROSCOPIC | 517 | ||
ANCILLARY TESTS | 517 | ||
DIFFERENTIAL DIAGNOSIS | 517 | ||
SELECTED REFERENCES | 517 | ||
Chapter 104.\rIntroduction to Thrombotic Microangiopathies | 518 | ||
TERMINOLOGY | 518 | ||
ETIOLOGY/PATHOGENESIS | 518 | ||
CLINICAL IMPLICATIONS | 518 | ||
LABORATORY INVESTIGATIONS | 519 | ||
MACROSCOPIC | 519 | ||
MICROSCOPIC | 519 | ||
DIAGNOSTIC CHECKLIST | 520 | ||
SELECTED REFERENCES | 520 | ||
Chapter 105.\rHemolytic Uremic Syndrome, Infection Related | 524 | ||
TERMINOLOGY | 525 | ||
ETIOLOGY/PATHOGENESIS | 525 | ||
CLINICAL ISSUES | 525 | ||
MICROSCOPIC | 526 | ||
ANCILLARY TESTS | 526 | ||
DIFFERENTIAL DIAGNOSIS | 526 | ||
DIAGNOSTIC CHECKLIST | 526 | ||
SELECTED REFERENCES | 526 | ||
Chapter 106.\rThrombotic Microangiopathy, Genetic | 528 | ||
TERMINOLOGY | 529 | ||
ETIOLOGY/PATHOGENESIS | 529 | ||
CLINICAL ISSUES | 530 | ||
MICROSCOPIC | 530 | ||
ANCILLARY TESTS | 530 | ||
DIFFERENTIAL DIAGNOSIS | 530 | ||
DIAGNOSTIC CHECKLIST | 530 | ||
SELECTED REFERENCES | 530 | ||
Chapter 107.\rThrombotic Microangiopathy, Autoimmune | 532 | ||
TERMINOLOGY | 533 | ||
ETIOLOGY/PATHOGENESIS | 533 | ||
CLINICAL ISSUES | 534 | ||
MICROSCOPIC | 534 | ||
ANCILLARY TESTS | 534 | ||
DIFFERENTIAL DIAGNOSIS | 534 | ||
SELECTED REFERENCES | 534 | ||
Chapter 108.\rThrombotic Microangiopathy, Drug Induced | 536 | ||
TERMINOLOGY | 537 | ||
ETIOLOGY/PATHOGENESIS | 537 | ||
CLINICAL ISSUES | 537 | ||
MICROSCOPIC | 538 | ||
ANCILLARY TESTS | 538 | ||
DIFFERENTIAL DIAGNOSIS | 538 | ||
DIAGNOSTIC CHECKLIST | 538 | ||
SELECTED REFERENCES | 538 | ||
Chapter 109.\rPostpartum Hemolytic Uremic Syndrome | 540 | ||
TERMINOLOGY | 541 | ||
ETIOLOGY/PATHOGENESIS | 541 | ||
CLINICAL ISSUES | 541 | ||
MICROSCOPIC | 542 | ||
ANCILLARY TESTS | 542 | ||
DIFFERENTIAL DIAGNOSIS | 542 | ||
SELECTED REFERENCES | 542 | ||
Chapter 110.\rScleroderma Renal Disease | 544 | ||
TERMINOLOGY | 545 | ||
ETIOLOGY/PATHOGENESIS | 545 | ||
CLINICAL ISSUES | 545 | ||
MICROSCOPIC | 546 | ||
ANCILLARY TESTS | 546 | ||
DIFFERENTIAL DIAGNOSIS | 546 | ||
DIAGNOSTIC CHECKLIST | 546 | ||
SELECTED REFERENCES | 546 | ||
Chapter 111.\rPreeclampsia, Eclampsia, HELLP Syndrome | 550 | ||
TERMINOLOGY | 551 | ||
ETIOLOGY/PATHOGENESIS | 551 | ||
CLINICAL ISSUES | 551 | ||
MICROSCOPIC | 551 | ||
ANCILLARY TESTS | 551 | ||
DIFFERENTIAL DIAGNOSIS | 551 | ||
DIAGNOSTIC CHECKLIST | 551 | ||
SELECTED REFERENCES | 551 | ||
Chapter 112.\rRadiation Nephropathy | 552 | ||
TERMINOLOGY | 553 | ||
ETIOLOGY/PATHOGENESIS | 553 | ||
CLINICAL ISSUES | 553 | ||
MICROSCOPIC | 553 | ||
ANCILLARY TESTS | 553 | ||
DIFFERENTIAL DIAGNOSIS | 553 | ||
DIAGNOSTIC CHECKLIST | 553 | ||
SELECTED REFERENCES | 553 | ||
Chapter 113.\rHereditary Endotheliopathy, Retinopathy, Nephropathy, and Stroke | 554 | ||
TERMINOLOGY | 555 | ||
ETIOLOGY/PATHOGENESIS | 555 | ||
CLINICAL ISSUES | 555 | ||
IMAGING | 555 | ||
MICROSCOPIC | 555 | ||
ANCILLARY TESTS | 555 | ||
DIFFERENTIAL DIAGNOSIS | 555 | ||
SELECTED REFERENCES | 555 | ||
Chapter 114.\rSickle Cell Nephropathy | 556 | ||
TERMINOLOGY | 557 | ||
ETIOLOGY/PATHOGENESIS | 557 | ||
CLINICAL ISSUES | 557 | ||
MACROSCOPIC | 557 | ||
MICROSCOPIC | 557 | ||
ANCILLARY TESTS | 557 | ||
DIFFERENTIAL DIAGNOSIS | 557 | ||
SELECTED REFERENCES | 557 | ||
Chapter 115.\rHypertensive Renovascular Disease | 560 | ||
TERMINOLOGY | 561 | ||
ETIOLOGY/PATHOGENESIS | 561 | ||
CLINICAL ISSUES | 561 | ||
MACROSCOPIC | 561 | ||
MICROSCOPIC | 562 | ||
ANCILLARY TESTS | 562 | ||
DIFFERENTIAL DIAGNOSIS | 562 | ||
SELECTED REFERENCES | 563 | ||
Chapter 116.\rRenal Artery Stenosis | 568 | ||
TERMINOLOGY | 569 | ||
ETIOLOGY/PATHOGENESIS | 569 | ||
CLINICAL ISSUES | 569 | ||
IMAGING | 569 | ||
MACROSCOPIC | 569 | ||
MICROSCOPIC | 570 | ||
ANCILLARY TESTS | 570 | ||
DIFFERENTIAL DIAGNOSIS | 570 | ||
DIAGNOSTIC CHECKLIST | 571 | ||
SELECTED REFERENCES | 571 | ||
Chapter 117.\rFibromuscular Dysplasia | 574 | ||
TERMINOLOGY | 575 | ||
ETIOLOGY/PATHOGENESIS | 575 | ||
CLINICAL ISSUES | 575 | ||
IMAGING | 575 | ||
MACROSCOPIC | 575 | ||
MICROSCOPIC | 575 | ||
DIFFERENTIAL DIAGNOSIS | 576 | ||
DIAGNOSTIC CHECKLIST | 576 | ||
SELECTED REFERENCES | 576 | ||
Chapter 118.\rNeurofibromatosis | 580 | ||
TERMINOLOGY | 581 | ||
ETIOLOGY/PATHOGENESIS | 581 | ||
CLINICAL ISSUES | 581 | ||
IMAGING | 581 | ||
MACROSCOPIC | 581 | ||
MICROSCOPIC | 581 | ||
DIFFERENTIAL DIAGNOSIS | 581 | ||
DIAGNOSTIC CHECKLIST | 581 | ||
SELECTED REFERENCES | 581 | ||
Chapter 119.\rRenal Vein Thrombosis | 584 | ||
TERMINOLOGY | 585 | ||
ETIOLOGY/PATHOGENESIS | 585 | ||
CLINICAL ISSUES | 585 | ||
MICROSCOPIC | 585 | ||
ANCILLARY TESTS | 585 | ||
DIFFERENTIAL DIAGNOSIS | 585 | ||
DIAGNOSTIC CHECKLIST | 585 | ||
SELECTED REFERENCES | 585 | ||
Chapter 120.\rRenal Artery Thrombosis | 586 | ||
TERMINOLOGY | 587 | ||
ETIOLOGY/PATHOGENESIS | 587 | ||
CLINICAL ISSUES | 587 | ||
IMAGING | 587 | ||
MACROSCOPIC | 587 | ||
MICROSCOPIC | 587 | ||
DIFFERENTIAL DIAGNOSIS | 587 | ||
SELECTED REFERENCES | 587 | ||
Chapter 121.\rAtheromatous Emboli | 588 | ||
TERMINOLOGY | 589 | ||
ETIOLOGY/PATHOGENESIS | 589 | ||
CLINICAL ISSUES | 589 | ||
MACROSCOPIC | 589 | ||
MICROSCOPIC | 589 | ||
ANCILLARY TESTS | 589 | ||
DIFFERENTIAL DIAGNOSIS | 589 | ||
SELECTED REFERENCES | 589 | ||
SECTION 4:\rTubulointerstitial Diseases | 590 | ||
Chapter 122.\rOverview and Classification of Tubulointerstitial Diseases | 592 | ||
TERMINOLOGY | 592 | ||
APPROACH TO DIAGNOSIS OF\rTUBULOINTERSTITIAL DISEASES | 592 | ||
SELECTED REFERENCES | 592 | ||
Chapter 123.\rDifferential Diagnosis of Acute Interstitial Nephritis | 594 | ||
ETIOLOGY/PATHOGENESIS | 595 | ||
CLINICAL ISSUES | 595 | ||
MICROSCOPIC | 595 | ||
DIFFERENTIAL DIAGNOSIS | 595 | ||
SELECTED REFERENCES | 595 | ||
Chapter 124.\rAcute Tubular Injury | 600 | ||
TERMINOLOGY | 601 | ||
ETIOLOGY/PATHOGENESIS | 601 | ||
CLINICAL ISSUES | 601 | ||
MACROSCOPIC | 601 | ||
MICROSCOPIC | 601 | ||
ANCILLARY TESTS | 602 | ||
DIFFERENTIAL DIAGNOSIS | 602 | ||
DIAGNOSTIC CHECKLIST | 602 | ||
SELECTED REFERENCES | 602 | ||
Chapter 125.\rRenal Cortical Necrosis | 606 | ||
TERMINOLOGY | 607 | ||
ETIOLOGY/PATHOGENESIS | 607 | ||
CLINICAL ISSUES | 607 | ||
IMAGING | 607 | ||
MACROSCOPIC | 607 | ||
MICROSCOPIC | 607 | ||
DIFFERENTIAL DIAGNOSIS | 607 | ||
DIAGNOSTIC CHECKLIST | 607 | ||
SELECTED REFERENCES | 607 | ||
Chapter 126.\rBile Cast Nephropathy | 608 | ||
TERMINOLOGY | 609 | ||
ETIOLOGY/PATHOGENESIS | 609 | ||
CLINICAL ISSUES | 609 | ||
MACROSCOPIC | 609 | ||
MICROSCOPIC | 609 | ||
DIFFERENTIAL DIAGNOSIS | 609 | ||
DIAGNOSTIC CHECKLIST | 609 | ||
SELECTED REFERENCES | 609 | ||
Chapter 127.\rDrug-Induced Acute Interstitial Nephritis | 612 | ||
TERMINOLOGY | 613 | ||
ETIOLOGY/PATHOGENESIS | 613 | ||
CLINICAL ISSUES | 613 | ||
IMAGING | 614 | ||
MACROSCOPIC | 614 | ||
MICROSCOPIC | 614 | ||
ANCILLARY TESTS | 614 | ||
DIFFERENTIAL DIAGNOSIS | 614 | ||
DIAGNOSTIC CHECKLIST | 615 | ||
SELECTED REFERENCES | 615 | ||
Chapter 128.\rPapillary Necrosis | 618 | ||
TERMINOLOGY | 619 | ||
ETIOLOGY/PATHOGENESIS | 619 | ||
CLINICAL ISSUES | 619 | ||
IMAGING | 619 | ||
MACROSCOPIC | 619 | ||
MICROSCOPIC | 619 | ||
ANCILLARY TESTS | 620 | ||
DIFFERENTIAL DIAGNOSIS | 620 | ||
DIAGNOSTIC CHECKLIST | 620 | ||
SELECTED REFERENCES | 620 | ||
Chapter 129.\rMyoglobinuria/Rhabdomyolysis/Hemoglobinuria | 622 | ||
TERMINOLOGY | 623 | ||
ETIOLOGY/PATHOGENESIS | 623 | ||
CLINICAL ISSUES | 623 | ||
MICROSCOPIC | 623 | ||
ANCILLARY TESTS | 623 | ||
DIFFERENTIAL DIAGNOSIS | 623 | ||
SELECTED REFERENCES | 623 | ||
Chapter 130.\rCisplatin Nephrotoxicity | 624 | ||
TERMINOLOGY | 625 | ||
ETIOLOGY/PATHOGENESIS | 625 | ||
CLINICAL ISSUES | 625 | ||
MACROSCOPIC | 625 | ||
MICROSCOPIC | 625 | ||
ANCILLARY TESTS | 625 | ||
DIFFERENTIAL DIAGNOSIS | 625 | ||
DIAGNOSTIC CHECKLIST | 625 | ||
SELECTED REFERENCES | 625 | ||
Chapter 131.\rOsmotic Tubulopathy | 626 | ||
TERMINOLOGY | 627 | ||
ETIOLOGY/PATHOGENESIS | 627 | ||
CLINICAL ISSUES | 627 | ||
MACROSCOPIC | 627 | ||
MICROSCOPIC | 627 | ||
ANCILLARY TESTS | 627 | ||
DIFFERENTIAL DIAGNOSIS | 628 | ||
DIAGNOSTIC CHECKLIST | 628 | ||
SELECTED REFERENCES | 628 | ||
Chapter 132.\rAntiviral Drug Nephrotoxicity | 630 | ||
TERMINOLOGY | 631 | ||
ETIOLOGY/PATHOGENESIS | 631 | ||
CLINICAL ISSUES | 631 | ||
MICROSCOPIC | 631 | ||
ANCILLARY TESTS | 632 | ||
DIFFERENTIAL DIAGNOSIS | 632 | ||
DIAGNOSTIC CHECKLIST | 632 | ||
SELECTED REFERENCES | 632 | ||
Chapter 133.\rAcute Phosphate Nephropathy | 636 | ||
TERMINOLOGY | 637 | ||
ETIOLOGY/PATHOGENESIS | 637 | ||
CLINICAL ISSUES | 637 | ||
MICROSCOPIC | 637 | ||
ANCILLARY TESTS | 637 | ||
DIFFERENTIAL DIAGNOSIS | 637 | ||
SELECTED REFERENCES | 637 | ||
Chapter 134.\rLithium-Induced Renal Disease | 638 | ||
TERMINOLOGY | 639 | ||
ETIOLOGY/PATHOGENESIS | 639 | ||
CLINICAL ISSUES | 639 | ||
MACROSCOPIC | 639 | ||
MICROSCOPIC | 639 | ||
ANCILLARY TESTS | 639 | ||
DIFFERENTIAL DIAGNOSIS | 639 | ||
DIAGNOSTIC CHECKLIST | 639 | ||
SELECTED REFERENCES | 639 | ||
Chapter 135.\rCalcineurin Inhibitor Toxicity | 642 | ||
TERMINOLOGY | 643 | ||
ETIOLOGY/PATHOGENESIS | 643 | ||
CLINICAL ISSUES | 643 | ||
MICROSCOPIC | 643 | ||
DIFFERENTIAL DIAGNOSIS | 644 | ||
DIAGNOSTIC CHECKLIST | 644 | ||
SELECTED REFERENCES | 644 | ||
Chapter 136.\rmTOR Inhibitor Toxicity | 648 | ||
TERMINOLOGY | 649 | ||
ETIOLOGY/PATHOGENESIS | 649 | ||
CLINICAL ISSUES | 649 | ||
MICROSCOPIC | 649 | ||
DIFFERENTIAL DIAGNOSIS | 649 | ||
SELECTED REFERENCES | 649 | ||
Chapter 137.\rWarfarin Nephropathy | 650 | ||
TERMINOLOGY | 651 | ||
ETIOLOGY/PATHOGENESIS | 651 | ||
CLINICAL ISSUES | 651 | ||
MICROSCOPIC | 651 | ||
DIFFERENTIAL DIAGNOSIS | 651 | ||
SELECTED REFERENCES | 651 | ||
Chapter 138.\rSepticemia/Shock | 652 | ||
TERMINOLOGY | 653 | ||
ETIOLOGY/PATHOGENESIS | 653 | ||
CLINICAL ISSUES | 653 | ||
MICROSCOPIC | 653 | ||
ANCILLARY TESTS | 653 | ||
DIFFERENTIAL DIAGNOSIS | 653 | ||
DIAGNOSTIC CHECKLIST | 653 | ||
SELECTED REFERENCES | 653 | ||
Chapter 139.\rLead and Other Heavy Metal Toxins | 656 | ||
TERMINOLOGY | 657 | ||
ETIOLOGY/PATHOGENESIS | 657 | ||
CLINICAL ISSUES | 657 | ||
MACROSCOPIC | 657 | ||
MICROSCOPIC | 657 | ||
ANCILLARY TESTS | 658 | ||
DIFFERENTIAL DIAGNOSIS | 658 | ||
DIAGNOSTIC CHECKLIST | 658 | ||
SELECTED REFERENCES | 658 | ||
Chapter 140.\rAristolochic Acid Nephropathy | 660 | ||
TERMINOLOGY | 661 | ||
ETIOLOGY/PATHOGENESIS | 661 | ||
CLINICAL ISSUES | 661 | ||
MACROSCOPIC | 661 | ||
MICROSCOPIC | 661 | ||
ANCILLARY TESTS | 661 | ||
DIFFERENTIAL DIAGNOSIS | 661 | ||
DIAGNOSTIC CHECKLIST | 661 | ||
SELECTED REFERENCES | 661 | ||
Chapter 141.\rBalkan Endemic Nephropathy | 662 | ||
TERMINOLOGY | 663 | ||
ETIOLOGY/PATHOGENESIS | 663 | ||
CLINICAL ISSUES | 663 | ||
MACROSCOPIC | 663 | ||
MICROSCOPIC | 663 | ||
DIFFERENTIAL DIAGNOSIS | 663 | ||
DIAGNOSTIC CHECKLIST | 663 | ||
SELECTED REFERENCES | 663 | ||
Chapter 142.\rEthylene Glycol Toxicity | 664 | ||
TERMINOLOGY | 665 | ||
ETIOLOGY/PATHOGENESIS | 665 | ||
CLINICAL ISSUES | 665 | ||
MACROSCOPIC | 665 | ||
MICROSCOPIC | 665 | ||
ANCILLARY TESTS | 665 | ||
DIFFERENTIAL DIAGNOSIS | 665 | ||
DIAGNOSTIC CHECKLIST | 665 | ||
SELECTED REFERENCES | 665 | ||
Chapter 143.\rArgyria | 666 | ||
TERMINOLOGY | 667 | ||
ETIOLOGY/PATHOGENESIS | 667 | ||
CLINICAL ISSUES | 667 | ||
MACROSCOPIC | 667 | ||
MICROSCOPIC | 667 | ||
ANCILLARY TESTS | 667 | ||
DIFFERENTIAL DIAGNOSIS | 667 | ||
DIAGNOSTIC CHECKLIST | 667 | ||
SELECTED REFERENCES | 667 | ||
Chapter 144.\rTubulointerstitial Nephritis With Uveitis | 668 | ||
TERMINOLOGY | 669 | ||
ETIOLOGY/PATHOGENESIS | 669 | ||
CLINICAL ISSUES | 669 | ||
MICROSCOPIC | 669 | ||
ANCILLARY TESTS | 669 | ||
DIFFERENTIAL DIAGNOSIS | 669 | ||
DIAGNOSTIC CHECKLIST | 669 | ||
SELECTED REFERENCES | 669 | ||
Chapter 145.\rSjögren Syndrome | 672 | ||
TERMINOLOGY | 673 | ||
ETIOLOGY/PATHOGENESIS | 673 | ||
CLINICAL ISSUES | 673 | ||
MICROSCOPIC | 673 | ||
ANCILLARY TESTS | 673 | ||
DIFFERENTIAL DIAGNOSIS | 673 | ||
DIAGNOSTIC CHECKLIST | 673 | ||
SELECTED REFERENCES | 673 | ||
Chapter 146.\rIgG4-Related Disease | 676 | ||
TERMINOLOGY | 677 | ||
ETIOLOGY/PATHOGENESIS | 677 | ||
CLINICAL ISSUES | 677 | ||
IMAGING | 677 | ||
MICROSCOPIC | 678 | ||
ANCILLARY TESTS | 678 | ||
DIFFERENTIAL DIAGNOSIS | 678 | ||
DIAGNOSTIC CHECKLIST | 679 | ||
SELECTED REFERENCES | 679 | ||
Chapter 147.\rIdiopathic Hypocomplementemic Tubulointerstitial Nephritis | 686 | ||
TERMINOLOGY | 687 | ||
ETIOLOGY/PATHOGENESIS | 687 | ||
CLINICAL ISSUES | 687 | ||
IMAGING | 687 | ||
MICROSCOPIC | 687 | ||
ANCILLARY TESTS | 687 | ||
DIFFERENTIAL DIAGNOSIS | 687 | ||
SELECTED REFERENCES | 687 | ||
Chapter 148.\rAnti-Tubular Basement Membrane Disease | 688 | ||
TERMINOLOGY | 689 | ||
ETIOLOGY/PATHOGENESIS | 689 | ||
CLINICAL ISSUES | 689 | ||
MICROSCOPIC | 689 | ||
ANCILLARY TESTS | 689 | ||
DIFFERENTIAL DIAGNOSIS | 689 | ||
DIAGNOSTIC CHECKLIST | 689 | ||
SELECTED REFERENCES | 689 | ||
Chapter 149.\rAnti-Brush Border Autoantibody Tubulointerstitial Nephritis | 690 | ||
TERMINOLOGY | 691 | ||
ETIOLOGY/PATHOGENESIS | 691 | ||
CLINICAL ISSUES | 691 | ||
MICROSCOPIC | 691 | ||
ANCILLARY TESTS | 691 | ||
DIFFERENTIAL DIAGNOSIS | 691 | ||
SELECTED REFERENCES | 691 | ||
Chapter 150.\rSarcoidosis | 692 | ||
TERMINOLOGY | 693 | ||
ETIOLOGY/PATHOGENESIS | 693 | ||
CLINICAL ISSUES | 693 | ||
IMAGING | 693 | ||
MICROSCOPIC | 693 | ||
ANCILLARY TESTS | 693 | ||
DIFFERENTIAL DIAGNOSIS | 693 | ||
DIAGNOSTIC CHECKLIST | 693 | ||
SELECTED REFERENCES | 693 | ||
Chapter 151.\rGiant Cell Tubulitis With TBM Deposits | 696 | ||
TERMINOLOGY | 697 | ||
ETIOLOGY/PATHOGENESIS | 697 | ||
CLINICAL ISSUES | 697 | ||
MICROSCOPIC | 697 | ||
ANCILLARY TESTS | 697 | ||
DIFFERENTIAL DIAGNOSIS | 697 | ||
SELECTED REFERENCES | 697 | ||
Chapter 152.\rMucin-1-Related Kidney Disease | 698 | ||
TERMINOLOGY | 699 | ||
ETIOLOGY/PATHOGENESIS | 699 | ||
CLINICAL ISSUES | 699 | ||
IMAGING | 699 | ||
MICROSCOPIC | 699 | ||
ANCILLARY TESTS | 699 | ||
DIFFERENTIAL DIAGNOSIS | 699 | ||
DIAGNOSTIC CHECKLIST | 699 | ||
SELECTED REFERENCES | 699 | ||
Chapter 153.\rUromodulin-Related Kidney Disease | 700 | ||
TERMINOLOGY | 701 | ||
ETIOLOGY/PATHOGENESIS | 701 | ||
CLINICAL ISSUES | 701 | ||
MACROSCOPIC | 701 | ||
MICROSCOPIC | 701 | ||
DIFFERENTIAL DIAGNOSIS | 701 | ||
DIAGNOSTIC CHECKLIST | 701 | ||
SELECTED REFERENCES | 701 | ||
Chapter 154.\rRenin Mutation With Tubulointerstitial Nephritis | 702 | ||
TERMINOLOGY | 703 | ||
ETIOLOGY/PATHOGENESIS | 703 | ||
CLINICAL ISSUES | 703 | ||
MICROSCOPIC | 703 | ||
ANCILLARY TESTS | 703 | ||
DIFFERENTIAL DIAGNOSIS | 703 | ||
SELECTED REFERENCES | 703 | ||
Chapter 155.\rKidney Disease Due to Mutations in HNF1B | 704 | ||
TERMINOLOGY | 705 | ||
ETIOLOGY/PATHOGENESIS | 705 | ||
CLINICAL ISSUES | 705 | ||
MACROSCOPIC | 705 | ||
MICROSCOPIC | 705 | ||
DIFFERENTIAL DIAGNOSIS | 705 | ||
DIAGNOSTIC CHECKLIST | 705 | ||
SELECTED REFERENCES | 705 | ||
Chapter 156.\rPrimary Hyperoxaluria | 706 | ||
TERMINOLOGY | 707 | ||
ETIOLOGY/PATHOGENESIS | 707 | ||
CLINICAL ISSUES | 707 | ||
MACROSCOPIC | 707 | ||
MICROSCOPIC | 707 | ||
DIFFERENTIAL DIAGNOSIS | 707 | ||
DIAGNOSTIC CHECKLIST | 707 | ||
SELECTED REFERENCES | 707 | ||
Chapter 157.\r2,8-Dihydroxyadeninuria | 708 | ||
TERMINOLOGY | 709 | ||
ETIOLOGY/PATHOGENESIS | 709 | ||
CLINICAL ISSUES | 709 | ||
MICROSCOPIC | 710 | ||
DIFFERENTIAL DIAGNOSIS | 710 | ||
DIAGNOSTIC CHECKLIST | 710 | ||
SELECTED REFERENCES | 710 | ||
Chapter 158.\rCystinosis | 712 | ||
TERMINOLOGY | 713 | ||
ETIOLOGY/PATHOGENESIS | 713 | ||
CLINICAL ISSUES | 713 | ||
MICROSCOPIC | 713 | ||
DIFFERENTIAL DIAGNOSIS | 713 | ||
DIAGNOSTIC CHECKLIST | 713 | ||
SELECTED REFERENCES | 713 | ||
Chapter 159.\rUric Acid Nephropathy/Gout | 714 | ||
TERMINOLOGY | 715 | ||
ETIOLOGY/PATHOGENESIS | 715 | ||
CLINICAL ISSUES | 715 | ||
MACROSCOPIC | 716 | ||
MICROSCOPIC | 716 | ||
DIFFERENTIAL DIAGNOSIS | 716 | ||
DIAGNOSTIC CHECKLIST | 716 | ||
SELECTED REFERENCES | 716 | ||
Chapter 160.\rBartter Syndrome | 718 | ||
TERMINOLOGY | 719 | ||
ETIOLOGY/PATHOGENESIS | 719 | ||
CLINICAL ISSUES | 719 | ||
MICROSCOPIC | 719 | ||
DIFFERENTIAL DIAGNOSIS | 719 | ||
DIAGNOSTIC CHECKLIST | 719 | ||
SELECTED REFERENCES | 719 | ||
Chapter 161.\rDent Disease | 720 | ||
TERMINOLOGY | 721 | ||
ETIOLOGY/PATHOGENESIS | 721 | ||
CLINICAL ISSUES | 721 | ||
MICROSCOPIC | 721 | ||
ANCILLARY TESTS | 721 | ||
DIFFERENTIAL DIAGNOSIS | 721 | ||
DIAGNOSTIC CHECKLIST | 721 | ||
SELECTED REFERENCES | 721 | ||
Chapter 162.\rOculocerebrorenal Syndrome of Lowe | 722 | ||
TERMINOLOGY | 723 | ||
ETIOLOGY/PATHOGENESIS | 723 | ||
CLINICAL ISSUES | 723 | ||
IMAGING | 723 | ||
MICROSCOPIC | 723 | ||
ANCILLARY TESTS | 723 | ||
DIFFERENTIAL DIAGNOSIS | 723 | ||
SELECTED REFERENCES | 723 | ||
Chapter 163.\rMethylmalonic Acidemia | 726 | ||
TERMINOLOGY | 727 | ||
ETIOLOGY/PATHOGENESIS | 727 | ||
CLINICAL ISSUES | 727 | ||
MICROSCOPIC | 727 | ||
DIFFERENTIAL DIAGNOSIS | 727 | ||
SELECTED REFERENCES | 727 | ||
Chapter 164.\rSystemic Karyomegaly | 728 | ||
TERMINOLOGY | 729 | ||
ETIOLOGY/PATHOGENESIS | 729 | ||
CLINICAL ISSUES | 729 | ||
MICROSCOPIC | 729 | ||
ANCILLARY TESTS | 729 | ||
DIFFERENTIAL DIAGNOSIS | 729 | ||
DIAGNOSTIC CHECKLIST | 729 | ||
SELECTED REFERENCES | 729 | ||
Chapter 165.\rMitochondriopathies | 730 | ||
TERMINOLOGY | 731 | ||
ETIOLOGY/PATHOGENESIS | 731 | ||
CLINICAL ISSUES | 731 | ||
MICROSCOPIC | 731 | ||
ANCILLARY TESTS | 731 | ||
DIFFERENTIAL DIAGNOSIS | 731 | ||
SELECTED REFERENCES | 731 | ||
Chapter 166.\rNephrocalcinosis | 734 | ||
TERMINOLOGY | 735 | ||
ETIOLOGY/PATHOGENESIS | 735 | ||
CLINICAL ISSUES | 735 | ||
IMAGING | 735 | ||
MICROSCOPIC | 735 | ||
ANCILLARY TESTS | 735 | ||
DIFFERENTIAL DIAGNOSIS | 735 | ||
DIAGNOSTIC CHECKLIST | 735 | ||
SELECTED REFERENCES | 735 | ||
Chapter 167.\rSecondary Oxalosis | 736 | ||
TERMINOLOGY | 737 | ||
ETIOLOGY/PATHOGENESIS | 737 | ||
CLINICAL ISSUES | 737 | ||
MICROSCOPIC | 737 | ||
DIFFERENTIAL DIAGNOSIS | 737 | ||
SELECTED REFERENCES | 737 | ||
Chapter 168.\rMesoamerican Nephropathy | 738 | ||
TERMINOLOGY | 739 | ||
ETIOLOGY/PATHOGENESIS | 739 | ||
CLINICAL ISSUES | 739 | ||
MICROSCOPIC | 739 | ||
ANCILLARY TESTS | 739 | ||
DIFFERENTIAL DIAGNOSIS | 739 | ||
SELECTED REFERENCES | 739 | ||
Chapter 169.\rExtramedullary Hematopoiesis | 740 | ||
TERMINOLOGY | 741 | ||
ETIOLOGY/PATHOGENESIS | 741 | ||
CLINICAL ISSUES | 741 | ||
MICROSCOPIC | 741 | ||
ANCILLARY TESTS | 741 | ||
DIFFERENTIAL DIAGNOSIS | 741 | ||
SELECTED REFERENCES | 741 | ||
SECTION 5:\rInfections of the Kidney | 745 | ||
Chapter 170.\rAcute Pyelonephritis | 746 | ||
TERMINOLOGY | 747 | ||
ETIOLOGY/PATHOGENESIS | 747 | ||
CLINICAL ISSUES | 747 | ||
IMAGING | 748 | ||
MACROSCOPIC | 748 | ||
MICROSCOPIC | 748 | ||
ANCILLARY TESTS | 748 | ||
DIFFERENTIAL DIAGNOSIS | 748 | ||
DIAGNOSTIC CHECKLIST | 749 | ||
SELECTED REFERENCES | 749 | ||
Chapter 171.\rChronic Pyelonephritis | 754 | ||
TERMINOLOGY | 755 | ||
ETIOLOGY/PATHOGENESIS | 755 | ||
CLINICAL ISSUES | 755 | ||
IMAGING | 755 | ||
MACROSCOPIC | 755 | ||
MICROSCOPIC | 755 | ||
ANCILLARY TESTS | 755 | ||
DIFFERENTIAL DIAGNOSIS | 755 | ||
DIAGNOSTIC CHECKLIST | 755 | ||
SELECTED REFERENCES | 755 | ||
Chapter 172.\rXanthogranulomatous Pyelonephritis | 758 | ||
TERMINOLOGY | 759 | ||
ETIOLOGY/PATHOGENESIS | 759 | ||
CLINICAL ISSUES | 759 | ||
IMAGING | 759 | ||
MACROSCOPIC | 759 | ||
MICROSCOPIC | 759 | ||
DIFFERENTIAL DIAGNOSIS | 759 | ||
DIAGNOSTIC CHECKLIST | 759 | ||
SELECTED REFERENCES | 759 | ||
Chapter 173.\rMalakoplakia | 762 | ||
TERMINOLOGY | 763 | ||
ETIOLOGY/PATHOGENESIS | 763 | ||
CLINICAL ISSUES | 763 | ||
MACROSCOPIC | 763 | ||
MICROSCOPIC | 763 | ||
ANCILLARY TESTS | 763 | ||
DIFFERENTIAL DIAGNOSIS | 763 | ||
DIAGNOSTIC CHECKLIST | 763 | ||
SELECTED REFERENCES | 763 | ||
Chapter 174.\rMegalocytic Interstitial Nephritis | 766 | ||
TERMINOLOGY | 767 | ||
ETIOLOGY/PATHOGENESIS | 767 | ||
CLINICAL ISSUES | 767 | ||
IMAGING | 767 | ||
MACROSCOPIC | 767 | ||
MICROSCOPIC | 767 | ||
ANCILLARY TESTS | 767 | ||
DIFFERENTIAL DIAGNOSIS | 767 | ||
SELECTED REFERENCES | 767 | ||
Chapter 175.\rTuberculosis | 768 | ||
TERMINOLOGY | 769 | ||
ETIOLOGY/PATHOGENESIS | 769 | ||
CLINICAL ISSUES | 769 | ||
IMAGING | 769 | ||
MACROSCOPIC | 769 | ||
MICROSCOPIC | 769 | ||
ANCILLARY TESTS | 769 | ||
DIFFERENTIAL DIAGNOSIS | 769 | ||
SELECTED REFERENCES | 769 | ||
Chapter 176.\rBCG Granulomatous Interstitial Nephritis | 770 | ||
TERMINOLOGY | 771 | ||
ETIOLOGY/PATHOGENESIS | 771 | ||
CLINICAL ISSUES | 771 | ||
MACROSCOPIC | 771 | ||
MICROSCOPIC | 771 | ||
ANCILLARY TESTS | 771 | ||
DIFFERENTIAL DIAGNOSIS | 771 | ||
SELECTED REFERENCES | 771 | ||
Chapter 177.\rLeprosy | 772 | ||
TERMINOLOGY | 773 | ||
ETIOLOGY/PATHOGENESIS | 773 | ||
CLINICAL ISSUES | 773 | ||
MICROSCOPIC | 773 | ||
ANCILLARY TESTS | 773 | ||
DIFFERENTIAL DIAGNOSIS | 773 | ||
SELECTED REFERENCES | 773 | ||
Chapter 178.\rNocardiosis | 774 | ||
TERMINOLOGY | 775 | ||
ETIOLOGY/PATHOGENESIS | 775 | ||
CLINICAL ISSUES | 775 | ||
IMAGING | 775 | ||
MICROSCOPIC | 775 | ||
ANCILLARY TESTS | 775 | ||
DIFFERENTIAL DIAGNOSIS | 775 | ||
SELECTED REFERENCES | 775 | ||
Chapter 179.\rLeptospirosis | 776 | ||
TERMINOLOGY | 777 | ||
ETIOLOGY/PATHOGENESIS | 777 | ||
CLINICAL ISSUES | 777 | ||
MACROSCOPIC | 777 | ||
MICROSCOPIC | 777 | ||
ANCILLARY TESTS | 777 | ||
DIFFERENTIAL DIAGNOSIS | 777 | ||
DIAGNOSTIC CHECKLIST | 777 | ||
SELECTED REFERENCES | 777 | ||
Chapter 180.\rMucormycosis | 778 | ||
TERMINOLOGY | 779 | ||
ETIOLOGY/PATHOGENESIS | 779 | ||
CLINICAL ISSUES | 779 | ||
MACROSCOPIC | 779 | ||
MICROSCOPIC | 779 | ||
DIFFERENTIAL DIAGNOSIS | 779 | ||
DIAGNOSTIC CHECKLIST | 779 | ||
SELECTED REFERENCES | 779 | ||
Chapter 181.\rCandidiasis | 780 | ||
TERMINOLOGY | 781 | ||
ETIOLOGY/PATHOGENESIS | 781 | ||
CLINICAL ISSUES | 781 | ||
IMAGING | 781 | ||
MACROSCOPIC | 781 | ||
MICROSCOPIC | 781 | ||
DIFFERENTIAL DIAGNOSIS | 781 | ||
DIAGNOSTIC CHECKLIST | 781 | ||
SELECTED REFERENCES | 781 | ||
Chapter 182.\rHistoplasmosis | 782 | ||
ETIOLOGY/PATHOGENESIS | 783 | ||
CLINICAL ISSUES | 783 | ||
MACROSCOPIC | 783 | ||
MICROSCOPIC | 783 | ||
DIFFERENTIAL DIAGNOSIS | 783 | ||
DIAGNOSTIC CHECKLIST | 783 | ||
SELECTED REFERENCES | 783 | ||
Chapter 183.\rCoccidioidomycosis | 784 | ||
TERMINOLOGY | 785 | ||
ETIOLOGY/PATHOGENESIS | 785 | ||
CLINICAL ISSUES | 785 | ||
IMAGING | 785 | ||
MACROSCOPIC | 785 | ||
MICROSCOPIC | 785 | ||
DIFFERENTIAL DIAGNOSIS | 785 | ||
DIAGNOSTIC CHECKLIST | 785 | ||
SELECTED REFERENCES | 785 | ||
Chapter 184.\rBlastomycosis | 786 | ||
ETIOLOGY/PATHOGENESIS | 787 | ||
CLINICAL ISSUES | 787 | ||
MACROSCOPIC | 787 | ||
MICROSCOPIC | 787 | ||
DIFFERENTIAL DIAGNOSIS | 787 | ||
DIAGNOSTIC CHECKLIST | 787 | ||
SELECTED REFERENCES | 787 | ||
Chapter 185.\rParacoccidioidomycosis | 788 | ||
TERMINOLOGY | 789 | ||
ETIOLOGY/PATHOGENESIS | 789 | ||
CLINICAL ISSUES | 789 | ||
MICROSCOPIC | 789 | ||
DIFFERENTIAL DIAGNOSIS | 789 | ||
DIAGNOSTIC CHECKLIST | 789 | ||
SELECTED REFERENCES | 789 | ||
Chapter 186.\rAspergillosis | 790 | ||
TERMINOLOGY | 791 | ||
ETIOLOGY/PATHOGENESIS | 791 | ||
CLINICAL ISSUES | 791 | ||
IMAGING | 791 | ||
MACROSCOPIC | 791 | ||
MICROSCOPIC | 791 | ||
DIFFERENTIAL DIAGNOSIS | 791 | ||
DIAGNOSTIC CHECKLIST | 791 | ||
SELECTED REFERENCES | 791 | ||
Chapter 187.\rCryptococcosis | 792 | ||
TERMINOLOGY | 793 | ||
ETIOLOGY/PATHOGENESIS | 793 | ||
CLINICAL ISSUES | 793 | ||
MACROSCOPIC | 793 | ||
MICROSCOPIC | 793 | ||
DIFFERENTIAL DIAGNOSIS | 793 | ||
SELECTED REFERENCES | 793 | ||
Chapter 188.\rMicrosporidiosis | 794 | ||
TERMINOLOGY | 795 | ||
ETIOLOGY/PATHOGENESIS | 795 | ||
CLINICAL ISSUES | 795 | ||
MICROSCOPIC | 795 | ||
ANCILLARY TESTS | 795 | ||
DIFFERENTIAL DIAGNOSIS | 795 | ||
SELECTED REFERENCES | 795 | ||
Chapter 189.\rRickettsial Infections | 796 | ||
TERMINOLOGY | 797 | ||
ETIOLOGY/PATHOGENESIS | 797 | ||
CLINICAL ISSUES | 797 | ||
MACROSCOPIC | 797 | ||
MICROSCOPIC | 797 | ||
ANCILLARY TESTS | 797 | ||
DIFFERENTIAL DIAGNOSIS | 797 | ||
DIAGNOSTIC CHECKLIST | 797 | ||
SELECTED REFERENCES | 797 | ||
Chapter 190.\rToxoplasmosis | 798 | ||
TERMINOLOGY | 799 | ||
ETIOLOGY/PATHOGENESIS | 799 | ||
CLINICAL ISSUES | 799 | ||
MICROSCOPIC | 799 | ||
ANCILLARY TESTS | 799 | ||
DIFFERENTIAL DIAGNOSIS | 799 | ||
SELECTED REFERENCES | 799 | ||
Chapter 191.\rHydatidosis | 800 | ||
TERMINOLOGY | 801 | ||
ETIOLOGY/PATHOGENESIS | 801 | ||
CLINICAL ISSUES | 801 | ||
IMAGING | 801 | ||
MACROSCOPIC | 801 | ||
MICROSCOPIC | 801 | ||
ANCILLARY TESTS | 801 | ||
DIFFERENTIAL DIAGNOSIS | 801 | ||
DIAGNOSTIC CHECKLIST | 801 | ||
SELECTED REFERENCES | 801 | ||
Chapter 192.\rPolyomavirus Nephritis | 804 | ||
TERMINOLOGY | 805 | ||
ETIOLOGY/PATHOGENESIS | 805 | ||
CLINICAL ISSUES | 805 | ||
MICROSCOPIC | 805 | ||
ANCILLARY TESTS | 806 | ||
DIFFERENTIAL DIAGNOSIS | 806 | ||
DIAGNOSTIC CHECKLIST | 806 | ||
SELECTED REFERENCES | 806 | ||
Chapter 193.\rAdenovirus Infection | 812 | ||
ETIOLOGY/PATHOGENESIS | 813 | ||
CLINICAL ISSUES | 813 | ||
MACROSCOPIC | 813 | ||
MICROSCOPIC | 813 | ||
ANCILLARY TESTS | 813 | ||
DIFFERENTIAL DIAGNOSIS | 813 | ||
DIAGNOSTIC CHECKLIST | 813 | ||
SELECTED REFERENCES | 813 | ||
Chapter 194.\rCytomegalovirus Infection | 816 | ||
TERMINOLOGY | 817 | ||
ETIOLOGY/PATHOGENESIS | 817 | ||
CLINICAL ISSUES | 817 | ||
MICROSCOPIC | 818 | ||
ANCILLARY TESTS | 818 | ||
DIFFERENTIAL DIAGNOSIS | 818 | ||
DIAGNOSTIC CHECKLIST | 818 | ||
SELECTED REFERENCES | 818 | ||
Chapter 195.\rHerpes Simplex Acute Nephritis | 820 | ||
TERMINOLOGY | 821 | ||
ETIOLOGY/PATHOGENESIS | 821 | ||
CLINICAL ISSUES | 821 | ||
MICROSCOPIC | 821 | ||
ANCILLARY TESTS | 821 | ||
DIFFERENTIAL DIAGNOSIS | 821 | ||
DIAGNOSTIC CHECKLIST | 821 | ||
SELECTED REFERENCES | 821 | ||
Chapter 196.\rEpstein-Barr Virus Nephritis | 822 | ||
TERMINOLOGY | 823 | ||
ETIOLOGY/PATHOGENESIS | 823 | ||
CLINICAL ISSUES | 823 | ||
MICROSCOPIC | 823 | ||
ANCILLARY TESTS | 823 | ||
DIFFERENTIAL DIAGNOSIS | 823 | ||
DIAGNOSTIC CHECKLIST | 823 | ||
SELECTED REFERENCES | 823 | ||
Chapter 197.\rHantavirus Nephropathy | 824 | ||
TERMINOLOGY | 825 | ||
ETIOLOGY/PATHOGENESIS | 825 | ||
CLINICAL ISSUES | 825 | ||
MICROSCOPIC | 825 | ||
ANCILLARY TESTS | 825 | ||
DIFFERENTIAL DIAGNOSIS | 825 | ||
SELECTED REFERENCES | 825 | ||
SECTION 6:\rDevelopmental Diseases | 827 | ||
Chapter 198.\rOverview of Congenital Anomalies of the Kidney and Urinary Tract | 828 | ||
TERMINOLOGY | 828 | ||
ETIOLOGY/PATHOGENESIS | 828 | ||
EPIDEMIOLOGY | 829 | ||
CLINICAL IMPLICATIONS | 829 | ||
MACROSCOPIC | 829 | ||
MICROSCOPIC | 829 | ||
SELECTED REFERENCES | 829 | ||
Chapter 199.\rDysplasia/Hypoplasia/Agenesis | 832 | ||
TERMINOLOGY | 833 | ||
ETIOLOGY/PATHOGENESIS | 833 | ||
CLINICAL ISSUES | 833 | ||
MACROSCOPIC | 834 | ||
MICROSCOPIC | 834 | ||
ANCILLARY TESTS | 834 | ||
DIFFERENTIAL DIAGNOSIS | 834 | ||
DIAGNOSTIC CHECKLIST | 835 | ||
SELECTED REFERENCES | 835 | ||
Chapter 200.\rOligomeganephronia | 838 | ||
TERMINOLOGY | 839 | ||
ETIOLOGY/PATHOGENESIS | 839 | ||
CLINICAL ISSUES | 839 | ||
IMAGING | 839 | ||
MACROSCOPIC | 839 | ||
MICROSCOPIC | 839 | ||
DIFFERENTIAL DIAGNOSIS | 839 | ||
DIAGNOSTIC CHECKLIST | 839 | ||
SELECTED REFERENCES | 839 | ||
Chapter 201.\rEctopia, Malrotation, Duplication, Fusion, Supernumerary Kidney | 840 | ||
ETIOLOGY/PATHOGENESIS | 841 | ||
CLINICAL ISSUES | 841 | ||
MACROSCOPIC | 841 | ||
MICROSCOPIC | 842 | ||
DIFFERENTIAL DIAGNOSIS | 842 | ||
DIAGNOSTIC CHECKLIST | 842 | ||
SELECTED REFERENCES | 842 | ||
Chapter 202.\rAsk-Upmark Kidney | 844 | ||
TERMINOLOGY | 845 | ||
ETIOLOGY/PATHOGENESIS | 845 | ||
CLINICAL ISSUES | 845 | ||
IMAGING | 845 | ||
MACROSCOPIC | 845 | ||
MICROSCOPIC | 845 | ||
DIFFERENTIAL DIAGNOSIS | 845 | ||
SELECTED REFERENCES | 845 | ||
Chapter 203.\rRenal Tubular Dysgenesis | 846 | ||
TERMINOLOGY | 847 | ||
ETIOLOGY/PATHOGENESIS | 847 | ||
CLINICAL ISSUES | 847 | ||
MACROSCOPIC | 847 | ||
MICROSCOPIC | 847 | ||
ANCILLARY TESTS | 847 | ||
DIFFERENTIAL DIAGNOSIS | 847 | ||
DIAGNOSTIC CHECKLIST | 847 | ||
SELECTED REFERENCES | 847 | ||
SECTION 7:\rCystic Diseases | 851 | ||
Chapter 204.\rOverview of Cystic Diseases | 852 | ||
PATHOGENETIC CLASSIFICATION | 852 | ||
EPIDEMIOLOGY | 852 | ||
ETIOLOGY/PATHOGENESIS | 852 | ||
MACROSCOPIC | 852 | ||
MICROSCOPIC | 853 | ||
HEREDITARY CYSTIC DISEASES | 853 | ||
NONHEREDITARY CYSTIC DISEASES | 853 | ||
NONNEPHRON CYSTIC DISEASE | 854 | ||
MIMICS OF CYSTIC DISEASES | 854 | ||
SELECTED REFERENCES | 854 | ||
Chapter 205.\rAutosomal Dominant Polycystic Kidney Disease | 858 | ||
TERMINOLOGY | 859 | ||
ETIOLOGY/PATHOGENESIS | 859 | ||
CLINICAL ISSUES | 859 | ||
MACROSCOPIC | 859 | ||
MICROSCOPIC | 859 | ||
DIFFERENTIAL DIAGNOSIS | 859 | ||
DIAGNOSTIC CHECKLIST | 859 | ||
SELECTED REFERENCES | 859 | ||
Chapter 206.\rAutosomal Recessive Polycystic Kidney Disease | 862 | ||
TERMINOLOGY | 863 | ||
ETIOLOGY/PATHOGENESIS | 863 | ||
CLINICAL ISSUES | 863 | ||
IMAGING | 863 | ||
MACROSCOPIC | 863 | ||
MICROSCOPIC | 863 | ||
ANCILLARY TESTS | 863 | ||
DIFFERENTIAL DIAGNOSIS | 863 | ||
SELECTED REFERENCES | 863 | ||
Chapter 207.\rNephronophthisis and Related Ciliopathies | 868 | ||
TERMINOLOGY | 869 | ||
ETIOLOGY/PATHOGENESIS | 869 | ||
CLINICAL ISSUES | 869 | ||
MACROSCOPIC | 869 | ||
MICROSCOPIC | 869 | ||
ANCILLARY TESTS | 869 | ||
DIFFERENTIAL DIAGNOSIS | 869 | ||
DIAGNOSTIC CHECKLIST | 870 | ||
SELECTED REFERENCES | 870 | ||
Chapter 208.\rvon Hippel-Lindau Disease | 874 | ||
TERMINOLOGY | 875 | ||
ETIOLOGY/PATHOGENESIS | 875 | ||
CLINICAL ISSUES | 875 | ||
MACROSCOPIC | 875 | ||
MICROSCOPIC | 875 | ||
DIFFERENTIAL DIAGNOSIS | 875 | ||
DIAGNOSTIC CHECKLIST | 875 | ||
SELECTED REFERENCES | 875 | ||
Chapter 209.\rTuberous Sclerosis Complex | 880 | ||
TERMINOLOGY | 881 | ||
ETIOLOGY/PATHOGENESIS | 881 | ||
CLINICAL ISSUES | 881 | ||
IMAGING | 881 | ||
MACROSCOPIC | 881 | ||
MICROSCOPIC | 882 | ||
ANCILLARY TESTS | 882 | ||
DIFFERENTIAL DIAGNOSIS | 882 | ||
DIAGNOSTIC CHECKLIST | 882 | ||
SELECTED REFERENCES | 882 | ||
Chapter 210. Zellweger Syndrome | 886 | ||
TERMINOLOGY | 887 | ||
ETIOLOGY/PATHOGENESIS | 887 | ||
CLINICAL ISSUES | 887 | ||
IMAGING | 887 | ||
MACROSCOPIC | 887 | ||
MICROSCOPIC | 887 | ||
ANCILLARY TESTS | 887 | ||
DIFFERENTIAL DIAGNOSIS | 887 | ||
SELECTED REFERENCES | 887 | ||
Chapter 211.\rMedullary Sponge Kidney | 890 | ||
TERMINOLOGY | 891 | ||
ETIOLOGY/PATHOGENESIS | 891 | ||
CLINICAL ISSUES | 891 | ||
IMAGING | 891 | ||
MACROSCOPIC | 891 | ||
MICROSCOPIC | 891 | ||
DIFFERENTIAL DIAGNOSIS | 891 | ||
SELECTED REFERENCES | 891 | ||
Chapter 212.\rCystic Nephroma | 892 | ||
TERMINOLOGY | 893 | ||
ETIOLOGY/PATHOGENESIS | 893 | ||
CLINICAL ISSUES | 893 | ||
IMAGING | 893 | ||
MACROSCOPIC | 893 | ||
MICROSCOPIC | 893 | ||
ANCILLARY TESTS | 893 | ||
DIFFERENTIAL DIAGNOSIS | 893 | ||
SELECTED REFERENCES | 893 | ||
Chapter 213.\rAcquired Cystic Disease | 896 | ||
TERMINOLOGY | 897 | ||
ETIOLOGY/PATHOGENESIS | 897 | ||
CLINICAL ISSUES | 897 | ||
MACROSCOPIC | 897 | ||
MICROSCOPIC | 897 | ||
ANCILLARY TESTS | 897 | ||
DIFFERENTIAL DIAGNOSIS | 897 | ||
DIAGNOSTIC CHECKLIST | 897 | ||
SELECTED REFERENCES | 897 | ||
Chapter 214.\rSimple and Miscellaneous Cysts | 900 | ||
ETIOLOGY/PATHOGENESIS | 901 | ||
CLINICAL ISSUES | 901 | ||
MACROSCOPIC | 901 | ||
MICROSCOPIC | 901 | ||
DIFFERENTIAL DIAGNOSIS | 901 | ||
SELECTED REFERENCES | 901 | ||
Chapter 215.\rRenal Lymphangioma/Lymphangiectasia | 902 | ||
TERMINOLOGY | 903 | ||
ETIOLOGY/PATHOGENESIS | 903 | ||
CLINICAL ISSUES | 903 | ||
MACROSCOPIC | 903 | ||
MICROSCOPIC | 903 | ||
DIFFERENTIAL DIAGNOSIS | 903 | ||
SELECTED REFERENCES | 903 | ||
SECTION 8:\rDiseases of the Collecting System | 907 | ||
Chapter 216.\rIntroduction to Impediments to Urine Flow | 908 | ||
TERMINOLOGY | 908 | ||
CLASSIFICATION | 908 | ||
ETIOLOGY/PATHOGENESIS | 909 | ||
CLINICAL IMPLICATIONS | 909 | ||
MACROSCOPIC | 909 | ||
MICROSCOPIC | 910 | ||
SELECTED REFERENCES | 910 | ||
Chapter 217.\rReflux Nephropathy | 912 | ||
TERMINOLOGY | 913 | ||
ETIOLOGY/PATHOGENESIS | 913 | ||
CLINICAL ISSUES | 913 | ||
IMAGING | 913 | ||
MACROSCOPIC | 913 | ||
MICROSCOPIC | 913 | ||
ANCILLARY TESTS | 914 | ||
DIFFERENTIAL DIAGNOSIS | 914 | ||
DIAGNOSTIC CHECKLIST | 914 | ||
SELECTED REFERENCES | 914 | ||
Chapter 218.\rObstructive Nephropathy | 918 | ||
TERMINOLOGY | 919 | ||
ETIOLOGY/PATHOGENESIS | 919 | ||
CLINICAL ISSUES | 919 | ||
IMAGING | 919 | ||
MACROSCOPIC | 919 | ||
MICROSCOPIC | 919 | ||
DIFFERENTIAL DIAGNOSIS | 919 | ||
SELECTED REFERENCES | 919 | ||
Chapter 219.\rNephrolithiasis | 924 | ||
TERMINOLOGY | 925 | ||
ETIOLOGY/PATHOGENESIS | 925 | ||
CLINICAL ISSUES | 925 | ||
MACROSCOPIC | 925 | ||
MICROSCOPIC | 926 | ||
ANCILLARY TESTS | 926 | ||
DIFFERENTIAL DIAGNOSIS | 926 | ||
DIAGNOSTIC CHECKLIST | 926 | ||
SELECTED REFERENCES | 926 | ||
Chapter 220.\rLoin Pain Hematuria Syndrome | 932 | ||
TERMINOLOGY | 933 | ||
ETIOLOGY/PATHOGENESIS | 933 | ||
CLINICAL ISSUES | 933 | ||
IMAGING | 933 | ||
MICROSCOPIC | 933 | ||
ANCILLARY TESTS | 933 | ||
DIFFERENTIAL DIAGNOSIS | 933 | ||
DIAGNOSTIC CHECKLIST | 933 | ||
SELECTED REFERENCES | 933 | ||
SECTION 9:\rDiseases of the Renal Allograft | 937 | ||
Chapter 221.\rPathological Classification of Renal Allograft Diseases | 938 | ||
TERMINOLOGY | 938 | ||
DEFINITIONS | 938 | ||
CATEGORY 1: ALLOIMMUNE RESPONSES | 938 | ||
CATEGORY 2: DRUG TOXICITY AND\rHYPERSENSITIVITY | 938 | ||
CATEGORY 3: INFECTION | 939 | ||
CATEGORY 4: ANATOMIC COMPLICATIONS | 939 | ||
CATEGORY 5: RECURRENT AND DE NOVO\rDISEASES | 939 | ||
CATEGORY 6: DONOR DISEASE | 939 | ||
CATEGORY 7: OTHER DISEASES | 939 | ||
NOTES | 939 | ||
SELECTED REFERENCES | 939 | ||
Chapter 222.\rEvaluation of the Allograft Kidney | 940 | ||
TERMINOLOGY | 940 | ||
ETIOLOGY/PATHOGENESIS | 940 | ||
CLINICAL IMPLICATIONS | 940 | ||
BIOPSY PROCESSING | 941 | ||
EVALUATION OF BIOPSY | 941 | ||
SPECIAL CONSIDERATIONS IN TRANSPLANT\rBIOPSIES | 941 | ||
NEW APPROACHES | 941 | ||
PROTOCOL BIOPSIES (SURVEILLANCE\rBIOPSIES) | 941 | ||
BANFF CLASSIFICATION | 942 | ||
BANFF SCORING CATEGORIES | 943 | ||
SELECTED REFERENCES | 943 | ||
Chapter 223.\rEvaluation of the Donor Kidney | 944 | ||
TERMINOLOGY | 945 | ||
CLINICAL ISSUES | 945 | ||
MICROSCOPIC | 945 | ||
ANCILLARY TESTS | 946 | ||
DIAGNOSTIC CHECKLIST | 946 | ||
REPORTING | 946 | ||
SELECTED REFERENCES | 946 | ||
Chapter 224.\rAcute T-Cell-Mediated Rejection | 948 | ||
TERMINOLOGY | 949 | ||
ETIOLOGY/PATHOGENESIS | 949 | ||
CLINICAL ISSUES | 949 | ||
MICROSCOPIC | 949 | ||
ANCILLARY TESTS | 950 | ||
DIFFERENTIAL DIAGNOSIS | 950 | ||
DIAGNOSTIC CHECKLIST | 950 | ||
GRADING | 950 | ||
SELECTED REFERENCES | 950 | ||
Chapter 225.\rChronic T-Cell-Mediated Rejection | 958 | ||
TERMINOLOGY | 959 | ||
ETIOLOGY/PATHOGENESIS | 959 | ||
CLINICAL ISSUES | 959 | ||
MICROSCOPIC | 959 | ||
ANCILLARY TESTS | 959 | ||
DIFFERENTIAL DIAGNOSIS | 959 | ||
DIAGNOSTIC CHECKLIST | 959 | ||
SELECTED REFERENCES | 959 | ||
Chapter 226.\rHyperacute Rejection | 960 | ||
TERMINOLOGY | 961 | ||
ETIOLOGY/PATHOGENESIS | 961 | ||
CLINICAL ISSUES | 961 | ||
MACROSCOPIC | 961 | ||
MICROSCOPIC | 961 | ||
ANCILLARY TESTS | 961 | ||
DIFFERENTIAL DIAGNOSIS | 961 | ||
SELECTED REFERENCES | 961 | ||
Chapter 227.\rAcute Humoral Rejection | 964 | ||
TERMINOLOGY | 965 | ||
ETIOLOGY/PATHOGENESIS | 965 | ||
CLINICAL ISSUES | 965 | ||
MICROSCOPIC | 965 | ||
ANCILLARY TESTS | 966 | ||
DIFFERENTIAL DIAGNOSIS | 966 | ||
SELECTED REFERENCES | 966 | ||
Chapter 228.\rChronic Antibody-Mediated Rejection | 970 | ||
TERMINOLOGY | 971 | ||
ETIOLOGY/PATHOGENESIS | 971 | ||
CLINICAL ISSUES | 971 | ||
MICROSCOPIC | 971 | ||
ANCILLARY TESTS | 972 | ||
DIFFERENTIAL DIAGNOSIS | 972 | ||
DIAGNOSTIC CHECKLIST | 973 | ||
REPORTING | 973 | ||
SELECTED REFERENCES | 973 | ||
Chapter 229.\rDiseases That Recur in Allografts | 980 | ||
TERMINOLOGY | 981 | ||
ETIOLOGY/PATHOGENESIS | 981 | ||
CLINICAL ISSUES | 981 | ||
MICROSCOPIC | 982 | ||
DIFFERENTIAL DIAGNOSIS | 982 | ||
DIAGNOSTIC CHECKLIST | 983 | ||
SELECTED REFERENCES | 983 | ||
Chapter 230.\rDe Novo Focal Segmental Glomerulosclerosis | 988 | ||
TERMINOLOGY | 989 | ||
ETIOLOGY/PATHOGENESIS | 989 | ||
CLINICAL ISSUES | 989 | ||
MICROSCOPIC | 989 | ||
ANCILLARY TESTS | 989 | ||
DIFFERENTIAL DIAGNOSIS | 989 | ||
DIAGNOSTIC CHECKLIST | 989 | ||
SELECTED REFERENCES | 989 | ||
Chapter 231.\rDe Novo Membranous Glomerulonephritis | 990 | ||
TERMINOLOGY | 991 | ||
ETIOLOGY/PATHOGENESIS | 991 | ||
CLINICAL ISSUES | 991 | ||
MACROSCOPIC | 991 | ||
MICROSCOPIC | 991 | ||
ANCILLARY TESTS | 991 | ||
DIFFERENTIAL DIAGNOSIS | 991 | ||
DIAGNOSTIC CHECKLIST | 991 | ||
SELECTED REFERENCES | 991 | ||
Chapter 232.\rAnti-GBM Disease in Alport Syndrome | 994 | ||
TERMINOLOGY | 995 | ||
ETIOLOGY/PATHOGENESIS | 995 | ||
CLINICAL ISSUES | 995 | ||
MICROSCOPIC | 995 | ||
ANCILLARY TESTS | 995 | ||
DIFFERENTIAL DIAGNOSIS | 995 | ||
DIAGNOSTIC CHECKLIST | 995 | ||
SELECTED REFERENCES | 995 | ||
Chapter 233.\rHyperperfusion Injury | 996 | ||
TERMINOLOGY | 997 | ||
ETIOLOGY/PATHOGENESIS | 997 | ||
CLINICAL ISSUES | 997 | ||
MICROSCOPIC | 997 | ||
ANCILLARY TESTS | 997 | ||
DIFFERENTIAL DIAGNOSIS | 997 | ||
DIAGNOSTIC CHECKLIST | 997 | ||
SELECTED REFERENCES | 997 | ||
Chapter 234.\rEngraftment Syndrome | 998 | ||
TERMINOLOGY | 999 | ||
ETIOLOGY/PATHOGENESIS | 999 | ||
CLINICAL ISSUES | 999 | ||
MICROSCOPIC | 999 | ||
ANCILLARY TESTS | 999 | ||
DIFFERENTIAL DIAGNOSIS | 999 | ||
SELECTED REFERENCES | 999 | ||
Chapter 235.\rAcute Tubular Injury in Allografts | 1002 | ||
TERMINOLOGY | 1003 | ||
ETIOLOGY/PATHOGENESIS | 1003 | ||
CLINICAL ISSUES | 1003 | ||
MACROSCOPIC | 1003 | ||
MICROSCOPIC | 1003 | ||
ANCILLARY TESTS | 1003 | ||
DIFFERENTIAL DIAGNOSIS | 1003 | ||
DIAGNOSTIC CHECKLIST | 1003 | ||
SELECTED REFERENCES | 1003 | ||
Chapter 236.\rUrine Leak | 1004 | ||
TERMINOLOGY | 1005 | ||
ETIOLOGY/PATHOGENESIS | 1005 | ||
CLINICAL ISSUES | 1005 | ||
IMAGING | 1005 | ||
MICROSCOPIC | 1005 | ||
DIFFERENTIAL DIAGNOSIS | 1005 | ||
SELECTED REFERENCES | 1005 | ||
Chapter 237.\rLymphocele | 1006 | ||
TERMINOLOGY | 1007 | ||
ETIOLOGY/PATHOGENESIS | 1007 | ||
CLINICAL ISSUES | 1007 | ||
IMAGING | 1007 | ||
MACROSCOPIC | 1007 | ||
MICROSCOPIC | 1007 | ||
DIFFERENTIAL DIAGNOSIS | 1007 | ||
DIAGNOSTIC CHECKLIST | 1007 | ||
SELECTED REFERENCES | 1007 | ||
Chapter 238.\rRenal Artery or Vein Thrombosis | 1008 | ||
TERMINOLOGY | 1009 | ||
ETIOLOGY/PATHOGENESIS | 1009 | ||
CLINICAL ISSUES | 1009 | ||
IMAGING | 1009 | ||
MACROSCOPIC | 1009 | ||
MICROSCOPIC | 1009 | ||
DIFFERENTIAL DIAGNOSIS | 1009 | ||
DIAGNOSTIC CHECKLIST | 1009 | ||
SELECTED REFERENCES | 1009 | ||
Chapter 239.\rTransplant Renal Artery Stenosis | 1010 | ||
TERMINOLOGY | 1011 | ||
ETIOLOGY/PATHOGENESIS | 1011 | ||
CLINICAL ISSUES | 1011 | ||
IMAGING | 1011 | ||
MACROSCOPIC | 1011 | ||
MICROSCOPIC | 1011 | ||
DIFFERENTIAL DIAGNOSIS | 1011 | ||
DIAGNOSTIC CHECKLIST | 1011 | ||
SELECTED REFERENCES | 1011 | ||
Chapter 240.\rPost-Transplant Lymphoproliferative Disease | 1012 | ||
TERMINOLOGY | 1013 | ||
ETIOLOGY/PATHOGENESIS | 1013 | ||
CLINICAL ISSUES | 1013 | ||
IMAGING | 1014 | ||
MACROSCOPIC | 1014 | ||
MICROSCOPIC | 1014 | ||
ANCILLARY TESTS | 1015 | ||
DIFFERENTIAL DIAGNOSIS | 1015 | ||
DIAGNOSTIC CHECKLIST | 1015 | ||
REPORTING | 1015 | ||
SELECTED REFERENCES | 1016 | ||
Chapter 241.\rProtocol Biopsies | 1022 | ||
TERMINOLOGY | 1022 | ||
CLINICAL IMPLICATIONS | 1022 | ||
MICROSCOPIC | 1022 | ||
DIAGNOSES | 1023 | ||
SELECTED REFERENCES | 1023 | ||
Chapter 242.\rAccommodation | 1026 | ||
TERMINOLOGY | 1027 | ||
ETIOLOGY/PATHOGENESIS | 1027 | ||
CLINICAL ISSUES | 1027 | ||
MICROSCOPIC | 1027 | ||
ANCILLARY TESTS | 1027 | ||
DIFFERENTIAL DIAGNOSIS | 1027 | ||
DIAGNOSTIC CHECKLIST | 1027 | ||
SELECTED REFERENCES | 1027 | ||
Chapter 243.\rTolerance | 1028 | ||
TERMINOLOGY | 1029 | ||
ETIOLOGY/PATHOGENESIS | 1029 | ||
CLINICAL ISSUES | 1029 | ||
MICROSCOPIC | 1029 | ||
DIAGNOSTIC CHECKLIST | 1029 | ||
SELECTED REFERENCES | 1029 | ||
Chapter 244.\rKidney Diseases in Non-Renal Transplant Recipients | 1030 | ||
TERMINOLOGY | 1031 | ||
ETIOLOGY/PATHOGENESIS | 1031 | ||
CLINICAL ISSUES | 1031 | ||
MICROSCOPIC | 1031 | ||
ANCILLARY TESTS | 1031 | ||
DIAGNOSTIC CHECKLIST | 1032 | ||
SELECTED REFERENCES | 1032 | ||
Chapter 245.\rGraft-vs.-Host Glomerulopathies | 1034 | ||
TERMINOLOGY | 1035 | ||
ETIOLOGY/PATHOGENESIS | 1035 | ||
CLINICAL ISSUES | 1035 | ||
MICROSCOPIC | 1035 | ||
ANCILLARY TESTS | 1035 | ||
DIFFERENTIAL DIAGNOSIS | 1035 | ||
SELECTED REFERENCES | 1035 | ||
SECTION 10:\rProtocols | 1037 | ||
Chapter 246.\rBiopsy Reports | 1038 | ||
TERMINOLOGY | 1038 | ||
COMPONENTS OF BIOPSY REPORT | 1038 | ||
SELECTED REFERENCES | 1039 | ||
Chapter 247.\rExamination of the End-Stage Kidney | 1040 | ||
TERMINOLOGY | 1040 | ||
EPIDEMIOLOGY | 1040 | ||
ETIOLOGY/PATHOGENESIS | 1040 | ||
MACROSCOPIC | 1041 | ||
MICROSCOPIC | 1041 | ||
SELECTED REFERENCES | 1042 | ||
Chapter 248.\rExamination of Tumor Nephrectomy Specimens for Nonneoplastic Diseases | 1046 | ||
TERMINOLOGY | 1046 | ||
EPIDEMIOLOGY | 1046 | ||
ETIOLOGY/PATHOGENESIS | 1046 | ||
CLINICAL IMPLICATIONS | 1046 | ||
MACROSCOPIC | 1047 | ||
MICROSCOPIC | 1047 | ||
SELECTED REFERENCES | 1047 | ||
Chapter 249.\rEvaluation of the Transplant Nephrectomy | 1052 | ||
TERMINOLOGY | 1052 | ||
ETIOLOGY/PATHOGENESIS | 1052 | ||
CLINICAL IMPLICATIONS | 1053 | ||
MACROSCOPIC | 1053 | ||
MICROSCOPIC | 1053 | ||
SELECTED REFERENCES | 1053 | ||
Chapter 250.\rNeedle Biopsy: Evaluation for Adequacy | 1058 | ||
SURGICAL/CLINICAL CONSIDERATION | 1058 | ||
SPECIMEN EVALUATION | 1058 | ||
REPORTING | 1059 | ||
PITFALLS | 1059 | ||
SELECTED REFERENCES | 1059 | ||
Chapter 251.\rEvaluation of Fibrosis | 1062 | ||
TERMINOLOGY | 1062 | ||
VALUE | 1062 | ||
MECHANISMS | 1062 | ||
METHODS FOR ASSESSMENT | 1062 | ||
SELECTED REFERENCES | 1063 | ||
Chapter 252.\rImmunofluorescence on Paraffin Tissue Sections | 1066 | ||
TERMINOLOGY | 1066 | ||
DIAGNOSTIC VALUE | 1066 | ||
PROTOCOLS | 1066 | ||
SELECTED REFERENCES | 1066 | ||
Chapter 253.\rEM Processing From Paraffin or Frozen Tissue | 1068 | ||
TERMINOLOGY | 1068 | ||
CLINICAL IMPLICATIONS | 1068 | ||
MACROSCOPIC | 1068 | ||
PROTOCOLS | 1068 | ||
MICROSCOPIC | 1069 | ||
SELECTED REFERENCES | 1069 | ||
Chapter 254.\rDetection of PLA2R Deposits and Autoantibodies | 1070 | ||
TERMINOLOGY | 1070 | ||
CLINICAL VALUE | 1070 | ||
PROTOCOLS | 1070 | ||
SELECTED REFERENCES | 1070 | ||
Chapter 255.\rAlport Collagen IV Immunofluorescence | 1072 | ||
TERMINOLOGY | 1072 | ||
IMMUNOFLUORESCENCE TECHNIQUE | 1072 | ||
INTERPRETATION | 1072 | ||
SELECTED REFERENCES | 1072 | ||
Chapter 256.\rC4d Immunohistochemistry/Immunofluorescence | 1074 | ||
TERMINOLOGY | 1074 | ||
COMPLEMENT COMPONENTS | 1074 | ||
DIAGNOSTIC VALUE | 1074 | ||
IMMUNOFLUORESCENCE TECHNIQUE (IF) | 1074 | ||
IMMUNOHISTOCHEMICAL TECHNIQUE (IHC) | 1075 | ||
DIAGNOSTIC SPECIFICITY | 1075 | ||
CONTROLS | 1075 | ||
SELECTED REFERENCES | 1075 | ||
Chapter 257.\rPolyomavirus Detection in Tissue | 1078 | ||
TERMINOLOGY | 1078 | ||
PROTOCOLS | 1078 | ||
SELECTED REFERENCES | 1078 | ||
Chapter 258.\rDiagnostic Genetics of Kidney Diseases | 1080 | ||
TERMINOLOGY | 1080 | ||
KIDNEY DISEASES AMENABLE TO\rDIAGNOSTIC CLINICAL SEQUENCING | 1080 | ||
ETIOLOGY/PATHOGENESIS | 1080 | ||
DIAGNOSTIC METHODS AND APPLICATIONS | 1081 | ||
TYPICAL STEPS IN WES ANALYSIS | 1081 | ||
CLINICAL IMPLICATIONS | 1082 | ||
SELECTED REFERENCES | 1082 | ||
INDEX | I-i |