BOOK
Intravascular Physiology, An Issue of Interventional Cardiology Clinics, E-Book
(2016)
Additional Information
Book Details
Abstract
This issue of Interventional Cardiology Clinics, edited by Allen Jeremias, is devoted to Intravascular Physiology. Dr. Jeremias assembled a group of expert contributors to review the following topics: Evolution of Coronary Physiology – Basic Concepts of FFR and CFR; Concept of "Functional PCI" – The Rational for Physiologic Lesion Assessment for PCI Guidance; Limitations and Pitfalls of FFR and Adenosine-Induced Hyperemia; Evidence for the Use of FFR to Guide Clinical Decision-Making – The Landmark FFR Clinical Trials; Evaluation of Microvascular Disease and Clinical Outcomes; Hyperemic vs. Resting Indices for the Assessment of CAD; FFR for the Evaluation of Tandem and Bifurcations Lesions, Left Main, and Acute Coronary Syndromes; and CT-FFR: Basic Concept and Clinical Implementation.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| INTERVENTIONAL CARDIOLOGY CLINICS | i | ||
| Copyright | ii | ||
| CONTRIBUTORS | iii | ||
| EDITOR-IN-CHIEF | iii | ||
| EDITOR | iii | ||
| AUTHORS | iii | ||
| CONTENTS | v | ||
| Prefaceix | v | ||
| History and Development of Coronary Flow Reserve and Fractional Flow Reserve for Clinical Applications397 | v | ||
| The Concept of Functional Percutaneous Coronary Intervention: Why Physiologic Lesion Assessment Is Integral to Coronary Ang ... | v | ||
| Limitations and Pitfalls of Fractional Flow Reserve Measurements and Adenosine-Induced Hyperemia419 | v | ||
| Landmark Fractional Flow Reserve Trials435 | vi | ||
| Evaluation of Microvascular Disease and Clinical Outcomes443 | vi | ||
| Can Resting Indices Obviate the Need for Hyperemia and Promote the Routine Use of Physiologically Guided Revascularization?459 | vi | ||
| Fractional Flow Reserve for the Evaluation of Tandem and Bifurcation Lesions, Left Main, and Acute Coronary Syndromes471 | vi | ||
| Noninvasive Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography for the Diagnosis of Lesion-speci ... | vii | ||
| Association of Wall Shear Stress with Coronary Plaque Progression and Transformation491 | vii | ||
| INTRAVASCULAR PHYSIOLOGY | viii | ||
| FORTHCOMING ISSUES | viii | ||
| RECENT ISSUES | viii | ||
| Coronary Physiology: Basic Concepts and Clinical Applications | ix | ||
| History and Development of Coronary Flow Reserve and Fractional Flow Reserve for Clinical Applications | 397 | ||
| KEY POINTS | 397 | ||
| INTRODUCTION | 397 | ||
| CLINICAL MOTIVATIONS | 398 | ||
| TECHNICAL DEVELOPMENTS | 400 | ||
| CORONARY FLOW RESERVE | 401 | ||
| FRACTIONAL FLOW RESERVE | 403 | ||
| SUMMARY | 405 | ||
| FINANCIAL SUPPORT AND RELATIONSHIPS WITH INDUSTRY | 406 | ||
| REFERENCES | 407 | ||
| The Concept of Functional Percutaneous Coronary Intervention | 411 | ||
| KEY POINTS | 411 | ||
| INTRODUCTION | 411 | ||
| APPROPRIATE USE CRITERIA FOR CORONARY REVASCULARIZATION | 412 | ||
| NONINVASIVE ISCHEMIC EVALUATION | 412 | ||
| ANATOMIC LESION SEVERITY AND CORONARY HEMODYNAMICS | 413 | ||
| INVASIVE EVALUATION OF ISCHEMIA | 414 | ||
| FRACTIONAL FLOW RESERVE AS AN INTEGRAL PART OF CORONARY ANGIOGRAPHY | 414 | ||
| A NEW APPROACH OF FUNCTIONAL ANGIOGRAPHY | 415 | ||
| SUMMARY | 416 | ||
| REFERENCES | 416 | ||
| Limitations and Pitfalls of Fractional Flow Reserve Measurements and Adenosine-Induced Hyperemia | 419 | ||
| KEY POINTS | 419 | ||
| INTRODUCTION | 419 | ||
| BASIC PRINCIPLES AND PREREQUISITES | 419 | ||
| PITFALLS OF FRACTIONAL FLOW RESERVE MEASUREMENTS | 420 | ||
| Mechanical Issues: Transducers, Zeros, Connections | 420 | ||
| Beat-to-Beat Variation | 421 | ||
| Damping of Pressure by Guiding Catheter | 421 | ||
| Catheters with Side Holes | 421 | ||
| Guide Wire Whipping Phenomenon | 423 | ||
| Wire Signal Drift | 423 | ||
| Wire Spasm and Pseudostenosis | 424 | ||
| Effect of Hydrostatic Pressure | 426 | ||
| Pressure Recovery | 426 | ||
| Effects of Central Venous Pressure | 426 | ||
| LIMITATIONS OF METHODS FOR INDUCTION OF HYPEREMIA | 427 | ||
| Methylxanthines and Adenosine Maximal Hyperemia | 427 | ||
| Intracoronary Versus Intravenous Adenosine-Induced Hyperemia | 428 | ||
| Peripheral Versus Central Intravenous Adenosine Infusion | 428 | ||
| Variable Responses to Intravenous Adenosine Infusion | 429 | ||
| LIMITATIONS OF A SINGLE CUTOFF VALUE | 431 | ||
| Fractional Flow Reserve in Difficult Anatomic Subsets | 432 | ||
| SUMMARY | 433 | ||
| REFERENCES | 433 | ||
| Landmark Fractional Flow Reserve Trials | 435 | ||
| KEY POINTS | 435 | ||
| INTRODUCTION | 435 | ||
| VALIDATION IN COMPARISON TO NONINVASIVE ISCHEMIA ASSESSMENT | 436 | ||
| SAFETY OF REVASCULARIZATION DEFERRAL WITH NORMAL FRACTIONAL FLOW RESERVE IN SINGLE-VESSEL CORONARY DISEASE | 436 | ||
| FRACTIONAL-FLOW-RESERVE-GUIDED REVASCULARIZATION IN MULTIVESSEL DISEASE | 437 | ||
| FRACTIONAL-FLOW-RESERVE-GUIDED REVASCULARIZATION AMONG PATIENTS WITH STABLE CORONARY DISEASE | 439 | ||
| SUMMARY/DISCUSSION | 440 | ||
| REFERENCES | 441 | ||
| Evaluation of Microvascular Disease and Clinical Outcomes | 443 | ||
| KEY POINTS | 443 | ||
| INTRODUCTION | 443 | ||
| DIRECT ANGIOGRAPHIC ASSESSMENT | 444 | ||
| CORONARY FLOW RESERVE | 446 | ||
| RESTING CORONARY FLOW PATTERNS | 448 | ||
| INDEX OF MICROCIRCULATORY RESISTANCE | 448 | ||
| INSTANTANEOUS HYPEREMIC DIASTOLIC VELOCITY-PRESSURE SLOPE | 450 | ||
| WAVE INTENSITY ANALYSIS | 451 | ||
| SUMMARY | 452 | ||
| REFERENCES | 453 | ||
| Can Resting Indices Obviate the Need for Hyperemia and Promote the Routine Use of Physiologically Guided Revascularization? | 459 | ||
| KEY POINTS | 459 | ||
| INTRODUCTION | 459 | ||
| IS HYPEREMIA PHYSIOLOGICALLY ESSENTIAL FOR THE PRESSURE-ONLY ASSESSMENT OF A STENOSIS? | 460 | ||
| IS HYPEREMIA ESSENTIAL TO UNMASK TRUE STENOSIS SEVERITY? | 462 | ||
| IS HYPEREMIA USEFUL IN VESSELS WITH TANDEM STENOSES? | 463 | ||
| FUTURE AREAS FOR DEVELOPMENT | 465 | ||
| SUMMARY | 467 | ||
| ACKNOWLEDGMENTS | 467 | ||
| REFERENCES | 467 | ||
| Fractional Flow Reserve for the Evaluation of Tandem and Bifurcation Lesions, Left Main, and Acute Coronary Syndromes | 471 | ||
| KEY POINTS | 471 | ||
| INTRODUCTION | 471 | ||
| FRACTIONAL FLOW RESERVE IN TANDEM LESIONS | 471 | ||
| FRACTIONAL FLOW RESERVE IN OSTIAL OR BIFURCATION LESIONS | 473 | ||
| Difficulty in Angiographic or Anatomic Evaluation | 473 | ||
| Outcomes of Percutaneous Coronary Intervention of Ostial or Bifurcation Lesions Are Poor | 474 | ||
| FRACTIONAL FLOW RESERVE IN LEFT MAIN CORONARY ARTERY DISEASE | 475 | ||
| FRACTIONAL FLOW RESERVE IN ACUTE CORONARY SYNDROMES | 475 | ||
| Fractional Flow Reserve in Chronic Myocardial Infarction | 477 | ||
| Fractional Flow Reserve of Nonculprit Vessel in ST Elevation Myocardial Infarction | 477 | ||
| Fractional Flow Reserve in Non–ST Elevation Myocardial Infarction | 477 | ||
| SUMMARY | 478 | ||
| REFERENCES | 478 | ||
| Noninvasive Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography for the Diagnosis of Lesion-speci ... | 481 | ||
| KEY POINTS | 481 | ||
| INTRODUCTION | 481 | ||
| FRACTIONAL FLOW RESERVE FOR THE ASSESSMENT OF LESION-SPECIFIC ISCHEMIA | 482 | ||
| NONINVASIVE FRACTIONAL FLOW RESERVE COMPUTED FROM STANDARD CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY IMAGES | 483 | ||
| EVIDENCE IN THE LITERATURE ON THE DIAGNOSTIC VALUE OF FFRCT | 484 | ||
| COST-EFFECTIVENESS OF FFRCT | 486 | ||
| FUTURE PERSPECTIVES | 486 | ||
| SUMMARY | 488 | ||
| REFERENCES | 488 | ||
| Association of Wall Shear Stress with Coronary Plaque Progression and Transformation | 491 | ||
| KEY POINTS | 491 | ||
| INTRODUCTION | 491 | ||
| ROLE OF WALL SHEAR STRESS IN ENDOTHELIAL FUNCTION | 492 | ||
| MECHANOTRANSDUCTION OF WALL SHEAR STRESS IN ENDOTHELIAL CELLS | 492 | ||
| EFFECTS OF WALL SHEAR STRESS ON THE ENDOTHELIUM | 493 | ||
| Endothelial Cell Phenotype | 493 | ||
| Low-density Lipoprotein Uptake | 493 | ||
| Nitric Oxide Production and Endothelial Nitric Oxide Synthase Expression | 493 | ||
| Oxidative Stress | 495 | ||
| Proinflammatory Pathways | 495 | ||
| ROLE OF WALL SHEAR STRESS IN CORONARY PLAQUE PROGRESSION | 495 | ||
| CORONARY PLAQUE TRANSFORMATION | 500 | ||
| SUMMARY | 500 | ||
| REFERENCES | 500 | ||
| ICCL_4_4_bmii - Copy (2) | 504 | ||
| ICCL_4_4_bmii - Copy | 505 | ||
| ICCL_4_4_bmii | 506 |