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Advances in Pediatrics, E-Book

Advances in Pediatrics, E-Book

Michael S. Kappy

(2015)

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Book Details

Abstract

Advances in Pediatrics reviews the most current practices in pediatrics. A distinguished editorial board, headed by Dr.Michael Kappy, identifies key areas of major progress and controversy and invites expert pediatricians to contribute original articles devoted to these topics. These insightful overviews bring concepts to a clinical level and explore their everyday impact on patient care. Topics such as fetal diagnosis and surgical intervention, updates in pharmacology, and fatty liver disease are represented, highlighting the most current and relevant information in the field.

Table of Contents

Section Title Page Action Price
Front Cover Cover
ADVANCES IN Pediatrics\r i
VOLUME 61 iii
Copyright\r v
Editors\r vii
Contributors\r ix
Contents\r xiii
Introduction xix
David Weyhe Smith, MD (1926–1981)—The Father of Dysmorphology 1
Acknowledgments 8
References 8
Immunization Update V 11
Introduction 11
Influenza vaccines 12
Meningococcal vaccines 15
Measles and pertussis 17
Human papillomavirus 19
Pneumococcal vaccines 21
Global immunization achievements and challenges 22
Typhoid vaccine 23
Yellow fever vaccine 23
Ebola virus vaccine 24
Summary 24
References 25
Salmonella Infections in Childhood 29
Key points 29
Introduction 29
Microbiology and nomenclature 30
Epidemiology 31
Nontyphoidal Salmonella in the United States 32
Nontyphoidal Salmonella outside the United States 34
Typhoidal Salmonella (Salmonella Typhi and Salmonella Paratyphi) 35
Pathogenesis 37
Pathogenesis of nontyphoidal Salmonella 38
Adherence and invasion 29
Inflammatory response and virulence 38
Pathogenesis in immunocompromised hosts 39
Pathogenesis of typhoidal Salmonella 40
Clinical manifestations 41
Nontyphoidal Salmonella 41
Acute gastroenteritis 42
Bloodstream infection 42
Focal nontyphoidal Salmonella infections 43
Asymptomatic carriage 43
Typhoid fever 44
Diagnosis 45
Management 46
Nontyphoidal Salmonella 46
Typhoid fever 49
Chronic carriage 51
Prevention 51
Nontyphoidal Salmonella 51
Typhoid fever 52
Summary 54
References 55
Childhood Tuberculosis 59
An Overview 59
Introduction 59
History 60
Epidemiology 61
Transmission 62
Pathogenesis 63
Clinical manifestations 66
Diagnosis 68
Latent tuberculosis 69
Active tuberculosis 72
Culture 73
Nucleic acid amplification tests 73
Loop-mediated isothermal amplification 74
BlaC-specific fluorogenic probe 74
Xpert MTB/RIF 74
Imaging 76
Extrapulmonary tuberculosis 76
Treatment 77
Latent infection 77
Active tuberculosis 79
Adjunctive therapy 80
Monitoring for adverse effects 80
Monitoring response 81
Alternative treatments 81
Multidrug-resistant tuberculosis 82
Vaccines 85
References 86
Child Advocacy in the Twenty-first Century 91
Advocacy defined 91
Why should pediatricians advocate? 91
The state of children’s health 92
The Affordable Care Act and improving population health 93
Patient-level advocacy 94
Community-level advocacy 94
Community partnerships 96
Legislative advocacy 97
Advocacy training for pediatricians 98
Statewide collaboratives 99
Does training in advocacy change pediatrician behavior? 100
Next steps 100
References 101
Children in Immigrant Families 105
The Foundation for America’s Future 105
Introduction 105
From the past to the present: immigration policy 106
Demographics and social determinants of children in immigrant families 108
The immigrant experience and health 110
The first 5 years: opportunities to develop human capital in early childhood 111
Neonatal health 112
Early prevention 113
Promotion of school readiness in the household setting: ages 0 to 3 years 115
Promotion of school readiness in the educational setting: ages 3 to 5 years 116
Children in immigrant families: health issues for school-aged children and adolescent youth 118
Asthma 119
Children with special health care needs 121
Obesity in children in immigrant families 121
Teen pregnancy in immigrant youth 122
Mental health and behavioral conditions 123
Educational outcomes of immigrant youth 123
Policy recommendations for children in immigrant families 124
Immigration reform and health care coverage 124
Access to health care 126
Addressing barriers to improving quality of health care 126
Family center policies 128
Educational policy for children in immigrant families 129
Economic policy and children in immigrant families 130
References 131
Preparing for Transition from Pediatric to Adult Care 137
Evaluation of a Physician Training Program 137
Introduction 138
Health care transition guidelines 139
Residency education 140
Methods 140
Planning and evaluation framework 140
Intervention elements 142
Didactic presentation 142
Electronic health records transition tool 137
Guidelines for Adolescent Preventive Services questionnaire 144
Patient materials and resources 145
Survey 145
Survey instrument 145
Analytical procedures 145
Chart review 146
Interviews 146
Sampling and recruitment 146
Instrument 147
Procedures 147
Results 147
Participants 147
Survey 147
Chart review 147
Interviews 150
Reach 150
Residents 151
Faculty 151
Effectiveness 151
Residents 154
Evidence-Based Psychological Treatments of Pediatric Mental Disorders 165
Key points 165
Internalizing disorders 165
General theoretical perspective of treatment 166
Implementation of treatment 167
Disorder-specific treatment 168
Anxiety disorders 165
Obsessive-compulsive disorder 170
Depression 171
Externalizing disorders 172
General theoretical perspective of treatment 172
Implementation of treatment 173
Behavioral parent training 173
School-based contingency management 175
Cognitive and social skills training 175
Disorder-specific treatments 176
Attention-deficit/hyperactivity disorder 176
Oppositional defiant disorder and conduct disorder 177
Summary 179
References 179
Gene Therapy for Blinding Pediatric Eye Disorders 185
Introduction 185
History of subretinal gene therapy 191
Current gene therapy trials 191
RPE65 gene therapy trials 191
Retinal disorders with gene therapy trials under way 196
Choroideremia 196
Screening for Critical Congenital Heart Disease in Newborns 211
Introduction 211
Epidemiology 212
Fetal ultrasonography, physical examination, pulse oximetry, and their role in detecting critical congenital heart disease 213
Pulse oximetry and basic criteria for screening test 216
Pulse oximetry screening: practical considerations 217
Economic considerations and cost 220
Limitations of pulse oximetry screening 221
Current status of existing screening programs 222
Model characteristics of critical congenital heart disease screening programs 223
Summary 224
References 224
Vascular Anomalies in Pediatrics 227
Introduction 227
Vascular tumors 228
Benign vascular tumors 228
Infantile hemangioma 227
Clinical features 228
Associated syndromes 231
Radiologic features 231
Pathology 231
Management 231
Congenital hemangioma 233
Hepatic hemangioma 234
Locally aggressive vascular tumor 237
Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon 237
Vascular malformations 238
Capillary malformation 238
Lymphatic malformation 239
Venous malformation 243
Arteriovenous malformation 246
Combined vascular malformations 247
Klippel-Trenaunay syndrome 247
Congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies syndrome 249
Parkes Weber syndrome (capillary malformation-arteriovenous malformation) 249
Summary 250
References 250
Hypo and Hyper 257
Common Pediatric Endocrine and Metabolic Emergencies 257
Introduction 257
Critical and archival specimens 259
Specific conditions 260
Hypoglycemia 260
Definitions and causes 257
Pathophysiology 257
History and physical examination 263
Laboratory evaluation 263
Treatment 265
Adrenal insufficiency 266
Causes 266
Pathophysiology 266
History and physical examination 268
Laboratory tests 268
Treatment 269
Hyponatremia 270
Causes 270
Pathophysiology 270
History and physical examination 272
Laboratory evaluation 273
Treatment 274
Hypernatremia 274
Causes/Pathophysiology 274
History and physical examination 276
Laboratory evaluation 276
Treatment 277
Hyperthyroidism 277
Causes 277
Pathophysiology 278
History and physical examination 278
Laboratory evaluation 279
Treatment 279
Nonspecific acute treatment 279
Specific acute treatment 279
Long-term treatment 280
Summary 280
References 281
Pediatric Headaches 283
Introduction 283
Migraine definition 283
Pathophysiology 284
Presentation 285
Treatment 285
Tension headache 287
Opiates 288
Chronic daily headache 288
Onabotulinum toxin 288
Cluster headache 289
Additional interventions 289
Cognitive behavioral therapy 289
Relaxation techniques 290
Biofeedback 290
Acupuncture 291
Summary 291
References 291