BOOK
Function Preservation in Laryngeal Cancer, An Issue of Otolaryngologic Clinics of North America, E-Book
(2015)
Additional Information
Book Details
Abstract
Cancers of the larynx, while survival outcomes increase, result in massive treatment damage from radiation and surgery. Patients often lose ability to speak and to eat. Preserving the larynx is a fine balance of cancer eradication, life extension, and quality of life. This issueof Otolaryngologic Clinics led by Dr Babak Sadoughi should be of interest to Otolaryngologists, Oncologists, Radiologists, and Speech Therapists. The issue approach reaches all the most important aspects of diagnosing and treating the patient with laryngeal cancer with a focus on preserving the voice in early laryngeal cancer and preserving and restoring function in advanced laryngeal cancer. Topics include: Functional Anatomy and Oncological Barriers of the Larynx; Evaluation of the Dysphonic Patient; Role of Advanced Laryngeal Imaging in Glottic Cancer; Laryngeal Function after Radiation Therapy; Management of Dysphonia after Radiation Therapy; Contemporary Surgical Management of Early Glottic Cancer; Voice Prognosis after Transoral Laser Microsurgery of the Larynx; Voice Rehabilitation after Transoral Laser Microsurgery of the Larynx; Quality of Life after Conservation Surgery for Laryngeal Cancer; Salvage Conservation Surgery of the Larynx; Airway Preservation in Ablative Laryngeal Surgery; Voice Restoration after Total Laryngectomy. A special article for Residents, written by a Resident, emphasizes essential "take home messages" for laryngeal function preservation diagnosis and treatment.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Program Objective | iii | ||
| Learning Objectives | iii | ||
| Accreditation | iii | ||
| Disclosure of Conflicts of Interest | iii | ||
| Unapproved/Off-Label Use Disclosure | iii | ||
| To Enroll | iii | ||
| Method of Participation | iv | ||
| CME Inquiries/Special Needs | iv | ||
| Contributors | v | ||
| Editor | v | ||
| Authors | v | ||
| Contents | ix | ||
| Preface: Function Preservation in Laryngeal Cancerxv | ix | ||
| Diagnosing Laryngeal Cancer | ix | ||
| Functional Anatomy and Oncologic Barriers of the Larynx533 | ix | ||
| Evaluation of the Dysphonic Patient (in: Function Preservation in Laryngeal Cancer)547 | ix | ||
| Role of Advanced Laryngeal Imaging in Glottic Cancer: Early Detection and Evaluation of Glottic Neoplasms565 | ix | ||
| Preserving Voice in Early Laryngeal Cancer | x | ||
| Laryngeal Function After Radiation Therapy585 | x | ||
| Management of Dysphonia After Radiation Therapy601 | x | ||
| Contemporary Surgical Management of Early Glottic Cancer611 | x | ||
| Voice Outcomes of Transoral Laser Microsurgery of the Larynx627 | x | ||
| Voice Rehabilitation After Transoral Laser Microsurgery of the Larynx639 | xi | ||
| Preserving and Restoring Function in Advanced Laryngeal Cancer | xi | ||
| Quality of Life After Conservation Surgery for Laryngeal Cancer655 | xi | ||
| Salvage Conservation Laryngeal Surgery After Radiation Therapy Failure667 | xi | ||
| Transoral and Transcervical Surgical Innovations in the Treatment of Glottic Cancer677 | xii | ||
| Voice Restoration After Total Laryngectomy687 | xii | ||
| Transcervical Conservation Laryngeal Surgery: An Anatomic Understanding to Enhance Functional and Oncologic Outcomes703 | xii | ||
| Function Preservation in Laryngeal Cancer | xv | ||
| Functional Anatomy and Oncologic Barriers of the Larynx | 533 | ||
| Key points | 533 | ||
| Introduction | 533 | ||
| Laryngeal anatomy | 533 | ||
| Laryngeal Regions | 533 | ||
| Borders of the Larynx | 534 | ||
| Laryngeal Spaces | 534 | ||
| Potential Spaces | 534 | ||
| Laryngeal Structures | 535 | ||
| Cartilage and membranes | 535 | ||
| Muscles | 535 | ||
| Mucosa and submucosal layers | 536 | ||
| Barriers and pathways to tumor spread | 536 | ||
| Embryologic Barriers | 536 | ||
| Anatomic Barriers and Facilitators to Tumor Spread | 537 | ||
| Fibrous barriers to tumor spread | 537 | ||
| Cartilaginous barriers to tumor spread | 538 | ||
| Soft tissue space | 540 | ||
| Venous structures | 540 | ||
| Muscle | 540 | ||
| Anterior commissure | 541 | ||
| Chemical Activators | 542 | ||
| Summary | 543 | ||
| References | 543 | ||
| Evaluation of the Dysphonic Patient (in: Function Preservation in Laryngeal Cancer) | 547 | ||
| Key points | 547 | ||
| Introduction | 547 | ||
| History | 549 | ||
| Office examination | 551 | ||
| Voice evaluation measures | 556 | ||
| Patient-based psychosocial impact | 556 | ||
| Auditory perceptual measures | 556 | ||
| Acoustic measures | 558 | ||
| Aerodynamic measures | 560 | ||
| Diagnostic specimen | 561 | ||
| Summary | 561 | ||
| References | 562 | ||
| Role of Advanced Laryngeal Imaging in Glottic Cancer | 565 | ||
| Key points | 565 | ||
| Introduction | 565 | ||
| Indirect laryngoscopy | 566 | ||
| Videostroboscopy | 567 | ||
| High-speed imaging | 567 | ||
| Videokymography | 568 | ||
| Optical coherence tomography | 569 | ||
| Autofluorescence | 571 | ||
| Biologic endoscopy techniques | 573 | ||
| Contact Endoscopy and Confocal Endomicroscopy | 573 | ||
| Raman Spectroscopy | 574 | ||
| Narrow Band Imaging | 575 | ||
| Computed tomography, MRI, PET, and ultrasound | 576 | ||
| Computed Tomography | 576 | ||
| MRI | 577 | ||
| PET | 577 | ||
| Ultrasound | 578 | ||
| Summary | 579 | ||
| References | 579 | ||
| Laryngeal Function After Radiation Therapy | 585 | ||
| Key points | 585 | ||
| Introduction | 585 | ||
| Definition: what is the function of the larynx? | 586 | ||
| Physiopathology | 587 | ||
| Diagnosis of laryngeal dysfunction after radiation therapy | 588 | ||
| Voice outcomes | 589 | ||
| Dysphagia outcomes | 591 | ||
| Feeding Tube Dependence | 591 | ||
| Aspiration | 592 | ||
| Stricture | 592 | ||
| Quality of Life | 593 | ||
| Strategies for prevention of laryngeal dysfunction | 593 | ||
| Summary | 594 | ||
| References | 594 | ||
| Management of Dysphonia After Radiation Therapy | 601 | ||
| Key points | 601 | ||
| Introduction | 601 | ||
| Patient evaluation overview | 602 | ||
| Management goals | 604 | ||
| Behavioral treatment options | 604 | ||
| Pharmacologic treatment options | 605 | ||
| Surgical treatment options | 605 | ||
| Summary | 606 | ||
| References | 607 | ||
| Contemporary Surgical Management of Early Glottic Cancer | 611 | ||
| Key points | 611 | ||
| Introduction | 611 | ||
| Patient evaluation | 612 | ||
| Transoral laser microsurgery | 613 | ||
| Resection Margins | 613 | ||
| Local Control and Organ Preservation | 615 | ||
| Anterior Commissure | 616 | ||
| Complications of Transoral Laser Microsurgery | 616 | ||
| Robot-assisted transoral laryngeal surgery | 617 | ||
| Open surgery | 617 | ||
| Evaluation of outcome | 619 | ||
| Summary | 620 | ||
| References | 620 | ||
| Voice Outcomes of Transoral Laser Microsurgery of the Larynx | 627 | ||
| Key points | 627 | ||
| Introduction | 627 | ||
| When to evaluate voice after transoral laser microsurgery | 628 | ||
| How is voice subjectively after transoral laser microsurgery? | 629 | ||
| How is voice-related quality of life after transoral laser microsurgery? | 630 | ||
| What are the objective acoustic results after transoral laser microsurgery? | 631 | ||
| What are the objective aerodynamic results after transoral laser microsurgery? | 632 | ||
| What are the factors involved in voice quality after transoral laser microsurgery? | 632 | ||
| How does voice after transoral laser microsurgery compare with voice after radiation therapy? | 633 | ||
| Summary | 634 | ||
| References | 634 | ||
| Voice Rehabilitation After Transoral Laser Microsurgery of the Larynx | 639 | ||
| Key points | 639 | ||
| Materials and methods | 640 | ||
| Patients | 640 | ||
| Voice Assessment Tools | 641 | ||
| Medialization Thyroplasty | 641 | ||
| Surgery for Anterior Synechiae (Lichtenberger Technique) | 642 | ||
| Results | 644 | ||
| Medialization Thyroplasty | 645 | ||
| Anterior Synechial Surgery | 646 | ||
| Discussion | 646 | ||
| Six-Month Interval | 647 | ||
| Injection | 647 | ||
| Voice Assessment | 647 | ||
| Open Surgery: Flaps and Laryngofissure | 648 | ||
| Medialization Thyroplasty | 648 | ||
| Synechiae of the anterior larynx | 648 | ||
| Mitomycin C | 649 | ||
| Speech Therapy | 649 | ||
| Anesthetic Considerations | 649 | ||
| Summary | 650 | ||
| References | 650 | ||
| Quality of Life After Conservation Surgery for Laryngeal Cancer | 655 | ||
| Key points | 655 | ||
| Overview | 655 | ||
| Importance of Quality of Life in the Management Algorithm | 656 | ||
| Relevant problems | 656 | ||
| Impact of Total Laryngectomy on Quality of Life | 656 | ||
| Morbidity of Radiation Therapy | 657 | ||
| The transoral alternative | 657 | ||
| Transoral Laser Microsurgery | 657 | ||
| Early Glottic Carcinoma | 658 | ||
| Clinical outcomes of open partial laryngectomy | 658 | ||
| Oncologic Outcomes | 658 | ||
| Quality of Life Outcomes | 659 | ||
| Advanced and recurrent laryngeal carcinoma | 661 | ||
| Summary | 662 | ||
| References | 662 | ||
| Salvage Conservation Laryngeal Surgery After Radiation Therapy Failure | 667 | ||
| Key points | 667 | ||
| Introduction | 667 | ||
| What is conservation laryngeal surgery? | 668 | ||
| Strategy of conservation laryngeal surgery after radiation therapy failure: when, for which tumors, and why? | 670 | ||
| Functional rehabilitation after salvage conservation laryngeal surgery for radiation therapy failure | 671 | ||
| Summary | 672 | ||
| References | 673 | ||
| Transoral and Transcervical Surgical Innovations in the Treatment of Glottic Cancer | 677 | ||
| Key points | 677 | ||
| Early glottic cancer | 677 | ||
| Background | 677 | ||
| Endoscopic Angiolytic Potassium Titanyl Phosphate Laser Treatment of Early Glottic Cancer | 678 | ||
| Salvage Endoscopic Angiolytic Potassium Titanyl Phosphate Laser Treatment of Early Glottic Cancer | 682 | ||
| Advanced glottic cancer | 682 | ||
| Extended Open Partial Laryngectomy with Aortic Homograft Reconstruction | 682 | ||
| References | 684 | ||
| Voice Restoration After Total Laryngectomy | 687 | ||
| Key points | 687 | ||
| History of voice restoration | 687 | ||
| Overview of voice restoration | 688 | ||
| Importance of voice restoration after total laryngectomy | 689 | ||
| Patient evaluation overview | 690 | ||
| Esophageal speech | 691 | ||
| Overview | 691 | ||
| Patient Evaluation | 691 | ||
| Management Goals | 691 | ||
| Treatment | 692 | ||
| Electrolarynx | 692 | ||
| Overview | 692 | ||
| Patient Evaluation | 692 | ||
| Management Goals | 693 | ||
| Treatment | 694 | ||
| Tracheoesophageal puncture | 694 | ||
| Overview | 694 | ||
| Patient Evaluation | 694 | ||
| Management Goals | 694 | ||
| Preoperative Planning and Preparation | 695 | ||
| Perioperative considerations | 695 | ||
| Primary Tracheoesophageal Puncture | 695 | ||
| Secondary Tracheoesophageal Puncture | 696 | ||
| Secondary Tracheoesophageal Puncture in Clinic | 696 | ||
| Procedural Approach | 696 | ||
| Secondary tracheoesophageal puncture in the operating room | 697 | ||
| Patient Positioning | 697 | ||
| Procedural Approach | 697 | ||
| Potential Complications and Management | 699 | ||
| Postprocedural Care | 699 | ||
| Rehabilitation and Recovery | 699 | ||
| Outcomes/Complications | 699 | ||
| Summary | 700 | ||
| References | 700 | ||
| Transcervical Conservation Laryngeal Surgery | 703 | ||
| Key points | 703 | ||
| Background | 703 | ||
| Guiding principles and understanding of tumor spread | 704 | ||
| Vertical partial laryngectomy | 706 | ||
| Anatomic Basis | 706 | ||
| Horizontal partial laryngectomy | 707 | ||
| Supraglottic partial laryngectomy | 707 | ||
| Anatomic Basis | 708 | ||
| Supracricoid partial laryngectomy with cricohyoidoepiglottopexy | 709 | ||
| Supracricoid partial laryngectomy with cricohyoidopexy | 711 | ||
| Anatomic Basis | 712 | ||
| Summary | 713 | ||
| Supplementary data | 713 | ||
| References | 713 | ||
| Index | 717 | ||
| A | 717 | ||
| C | 717 | ||
| D | 717 | ||
| E | 718 | ||
| F | 718 | ||
| G | 718 | ||
| H | 719 | ||
| L | 719 | ||
| M | 721 | ||
| N | 721 | ||
| O | 722 | ||
| P | 722 | ||
| Q | 722 | ||
| R | 722 | ||
| S | 722 | ||
| T | 722 | ||
| U | 723 | ||
| V | 723 | ||
| Diagnosing Laryngeal Cancer | A1 | ||
| Preserving Voice in Early Laryngeal Cancer | A3 | ||
| Preserving and Restoring Function in Advanced Laryngeal Cancer | A5 |