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Abstract
The modern synthetic chemist applies all the tools available to identify the drug-like molecules with the best chances of becoming novel drugs. This book will act as a primer for graduates and postgraduates interested in a career in drug discovery. It covers both synthetic technologies currently impacting medicinal chemistry and emerging areas. The chapters focus on topics including: parallel medicinal chemistry; solid supported reagents; microwave assisted chemistry; flow synthesis, and high throughput reaction screening.
Elizabeth Farrant is Head of Chemical Technologies and Analytical Sciences at Pfizer. Previously Assistant Director, Technology development GSK, Harlow. Dr Farrant has more than10 years experience in pharmaceutical research working in combinatorial chemistry, medicinal chemistry and new technologies at the forefront of developing new approaches to synthetic chemistry including parallel chemistry and purification and flow chemistry.