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Obstetric and Gynecologic Dermatology E-Book

Obstetric and Gynecologic Dermatology E-Book

Martin M. Black | Christina Ambros-Rudolph | Libby Edwards | Peter J. Lynch

(2008)

Additional Information

Book Details

Abstract

Highly Commended, Dermatology, BMA Awards 2009

Completely updated throughout—and still the only reference of its kind—the new edition of this well-respected resource offers you a practical guide for the evaluation, diagnosis, and management of a full range of common and uncommon obstetric and gynecologic skin disorders. Expanded coverage—including chapters on vulval vaginal disease help you meet more clinical challenges, while more than 460 illustrations emphasize pathologic and clinical appearances of dermatologic problems, providing essential visual guidance for the most informed diagnoses. Enhanced basic dermatologic information, such as general introductions to treatment, treatment options, and rashes, makes this an excellent guide for dermatologist and non-dermatologists, as well as obstetricians and gynecologists.

  • Features the contributions of a team of international experts who provide a global perspective on today’s best practices.
  • Provides exceptional visual guidance of both obstetric and gynecologic dermatoses, making this a convenient one-stop consultation reference.
  • Includes more than 460 illustrations that clarify the key features of diseases and provide a greater “true-life” practice perspective for making accurate diagnoses.
  • Covers a full spectrum of conditions, including vulvar dermatoses, dermatoses of pregnancy, effect of pregnancy on other skin disorders, and more, to help you meet a full range of clinical challenges for diverse patient populations.
  • Provides new information and illustrations in an expanded vulval section that equip you with a wider range of gynecologic dermatoses and treatment options for your most challenging clinical cases.
  • Features the contributions of two new internationally recognized editors—known for their work in genital dermatology—who broaden the global appeal and relevance of the coverage.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Obstetric and Gynecologic Dermatology iii
Copyright Page iv
Contents v
Preface ix
List of Contributors xi
Dedications xiii
Part I: Obstetrics 1
CHAPTER 1. Hormonal Changes during Puberty, Pregnancy, and the Menopause 3
Introduction 3
Hypothalamic-pituitary axis 3
Puberty 4
The menstrual cycle 7
Pregnancy 9
The climacteric and the menopause 10
Conclusion 12
References 12
CHAPTER 2. Perimenstrual Skin Eruptions, Autoimmune Progesterone Dermatitis, Autoimmune Estrogen Dermatitis 13
Introduction 13
Sex hormones and the skin 13
The perimenstrual dermatoses 14
Autoimmune progesterone dermatitis 16
Autoimmune estrogen dermatitis 21
References 21
CHAPTER 3. Physiologic Skin Changes of Pregnancy 23
Hyperpigmentation 23
Striae distensae 24
Hair and nail changes 24
Vascular changes 28
Eccrine/apocrine gland activity 29
Immune system changes 29
References 30
CHAPTER 4. A Systematic Approach to the Dermatoses of Pregnancy 31
Introduction 31
Historical background 31
Algorithmic approach to the pregnant woman presenting with pruritus 34
Conclusion 34
References 36
Etiology 37
Clinical features 37
Hydatidiform mole and choriocarcinoma 40
Fetal and neonatal disease 40
Associated autoimmune diseases 41
Pathology 41
Differential diagnosis 43
Treatment 43
References 46
CHAPTE 6. Polymorphic Eruption of Pregnancy 49
Introduction 49
Historical background 49
Etiology 49
Clinical features 50
Histopathology and immunofluorescence 53
Differential diagnosis 53
Prognosis 53
Management 54
References 54
CHAPTER 7. Intrahepatic Cholestasis of Pregnancy 57
Introduction 57
Historical background 57
Etiology 58
Clinical and laboratory findings 58
Fetal risks 60
Management 61
References 62
CHAPTER 8. Atopic Eruption of Pregnancy 65
Introduction 65
Historical background 65
Etiology 66
Clinical and diagnostic features 66
Prognosis 68
Management 68
References 71
CHAPTER 9. The Papular and Pruritic Dermatoses of Pregnancy 73
Introduction 73
Prurigo of pregnancy 73
Papular dermatitis of pregnancy 75
Pruritic folliculitis of pregnancy 76
References 77
CHAPTER 10. Effect of Pregnancy on Other Skin Disorders 79
Introduction 79
Psoriasis 79
Impetigo herpetiformis 82
Acne vulgaris 83
Hidradenitis suppurativa 85
Erythema nodosum 85
Bullous disorders 86
Neoplasia 91
Miscellaneous conditions 93
Conclusion 96
References 96
CHAPTER 11. Connective Tissue Diseases in Pregnancy 99
Introduction 99
Rheumatoid arthritis 99
Systemic lupus erythematosus 99
Antiphospholipid syndrome 102
Scleroderma 103
Dermatomyositis and polymyositis 103
Ehler…Danlos syndrome 104
Pseudoxanthoma elasticum 106
References 106
CHAPTER 12. Infectious Diseases in Pregnancy 107
Viral exanthems and pregnancy 107
Human immunodeficiency virus 111
Herpes simplex virus 113
Human papillomavirus 117
Pregnancy and leprosy 118
References 118
Part II: Gynecologic Dermatology 121
CHAPTER 13. Vulvar Anatomy 123
Introduction 123
Embryology 123
Blood supply 129
Nerve supply 130
Muscles 131
References 131
CHAPTER 14. Lichen Sclerosus 133
Epidemiology and clinical manifestations 133
Diagnosis and differential diagnosis 135
Laboratory findings and histology 136
Pathogenesis 137
Therapy and prognosis 139
Special issues 142
Lichen sclerosus 144
References 144
Further reading 145
CHAPTER 15. Lichen Planus 147
Epidemiology and clinical manifestations 147
Diagnosis and differential diagnosis 150
Laboratory and histology 152
Pathogenesis 153
Therapy and prognosis 153
References 156
Further reading 156
CHAPTER 16. Vulvar Pruritus and Lichen Simplex Chronicus 157
Lichen simplex chronicus 158
References 166
Further reading 166
CHAPTER 17. Vulvar Dermatoses: Papulosquamous Diseases 167
Psoriasis 167
Reiter's syndrome 172
Tinea cruris 173
Erythrasma 175
Pityriasis versicolor (tinea versicolor) 175
Pityriasis rosea 176
Plasma cell vulvitis (vulvitis plasmacellularis, Zoon's vulvitis, vulvitis circumscripta plasmacellularis) 176
Lupus erythematosus 178
Vulvar intraepithelial neoplasia 3 (Bowen's disease, squamous cell carcinoma in situ: discussed primarily in chapter 23) 179
References 180
Further reading 180
CHAPTER 18. Vulvar Dermatoses: the Eczematous Diseases 181
Atopic/neurodermatitis and lichen simplex chronicus 182
Contact dermatitis 182
Intertrigo and seborrheic dermatitis 187
Candidal vulvitis 188
Hailey–Hailey disease (familial benign pemphigus) 190
Darier's disease (Darier–White disease, keratosis follicularis) 192
References 194
Further reading 194
CHAPTER 19. Skin-Colored and Red Papules and Nodules 195
Skin-Colored Papules And Plaques 195
Genital warts (human papillomavirus infection) 195
Molluscum contagiosum 201
Vestibular papillomatosis 204
Sebaceous gland hyperplasia (Fordyce condition) 204
Skin tags 205
Condyloma latum 205
Fox-Fordyce disease 206
Miscellaneous disorders 206
Red Papules And Nodules 206
Hidradenitis suppurativa 207
Bacterial folliculitis 210
Furuncles and abscesses 210
Keratosis pilaris 211
Urethral caruncle and urethral prolapse 211
Erosive papulododular dermatosis 212
Miscellaneous red nodules 212
References 214
Further reading 215
CHAPTER 20. Pustules, Vesicles, Bullae, and Erosions 217
Pustules 217
Folliculitis 217
Cutaneous candidiasis (see Chapters 18 and 24 for primary discussion) 220
Keratosis pilaris (discussed primarily in Chapter 19) 220
Mollusca contagiosa (discussed primarily in Chapter 19) 220
VESICLES, BULLAE, AND EROSIONS 220
VESICULAR DISEASE 221
Herpes simplex virus infection 221
Varicella-zoster virus infection; varicella (chickenpox), herpes zoster virus infection (shingles) 225
Lymphangioma circumscriptum/lymphangiectasia 228
BULLOUS DISEASE 229
Bullous erythema multiforme (erythema multiforme major, stevens…Johnson syndrome, toxic epidermal necrolysis) 229
Fixed drug eruption 232
Cicatricial pemphigoid (benign mucous membrane pemphigoid) 233
Fissures 236
Bullous impetigo 236
Bullous pemphigold 237
Pemphigus vulgarls 237
References 238
Further reading 239
CHAPTER 21. Vulvar Ulcers 241
Noninfectious Ulcers 241
Aphthous ulcer and complex aphthosis 241
Behçet's disease 245
Crohn's disease 246
Excoriation and factitial disease 249
Miscellaneous noninfectious ulcers 251
Infectious ulcers 251
Primary syphilis 251
Miscellaneous genital ulcers 254
References 255
Further reading 256
CHAPTER 22. Disorders of Pigmentation 257
Hypopigmentation 257
Vitiligo 257
Postinflammatory hypopigmentation 259
Lichen sclerosus (lichen sclerosus et atrophicus, hypoplastic dystrophy): see Chapter 14 259
Hyperkeratosis 259
Hyperpigmentation 260
Vulvar melanosis/vulvar lentiginosis 260
Postinflammatory hyperpigmentation 262
Physiologic hyperpigmentation 263
Acanthosis nigricans 263
References 264
Further reading 265
CHAPTER 23. Vulvar Neoplasms and Cysts 267
Cysts 267
Epidermoid cysts 267
Bartholin cysts 268
Cysts of the canal of Nuck (female hydrocele) 270
Mesonephric and paramesonephric duct cysts 270
Mucinous cysts 270
Pilonidal cysts (pilonidal sinus) 271
Benign Neoplasms 271
Melanocytic nevi (moles) 271
Skin tags and fibroepithelial polyps 274
Seborrheic keratoses 275
Hemangiomas 276
Angiokeratomas 278
Syringomas 279
Hidradenoma papilliferum 280
Neurofibromas 280
Lipomas 280
Fibromas 281
Granular cell tumors 281
Langerhans cell histiocytosis 282
Miscellaneous benign neoplasms of the vulva 282
Premalignant and Malignant Neoplasm 282
Vulvar intraepithelial neoplasia 282
Invasive squamous cell carcinoma 286
Verrucous carcinoma 287
Basal cell carcinoma 288
Extramammary Paget's disease 289
Atypical nevi 293
Melanoma 294
Miscellaneous rare malignancies 298
References 298
Further reading 299
CHAPTER 24. Vaginitis 301
Candid vulvovaginitis 301
Bacterial vaginosis (nonspecific vaginitis,haemophilu vaginitis,gardnerella vaginali vaginitis, anaerobic vaginitiss) 305
Trichomonas 306
Bacterial vaginitis 307
Lactobacillus vaginosis 309
Cytolytic vaginosis 309
Atrophic vaginitis 310
Desquamative inflammatory vaginitis 312
Inflammatory vaginitis on the basis of specific mucosal erosive dermatoses (see chapter 20) 315
Physiologic discharge 315
Discharge and odor 315
Vestibulodynia (vulvar vestibulitis) 316
References 316
Further reading 316
CHAPTER 25. Vulvar Edema 317
Acute vulvar edema 317
Chronic vulvar edema 318
References 322
Further reading 322
CHAPTER 26. Pediatric Vulvar Disorders 323
Introduction 323
Congenital vulvar abnormalities 323
Vulvar dermatoses 326
Infections 335
Infestations 338
Vaginitis due to a foreign body 338
Sexual abuse 338
Bullous diseasee 339
Miscellaneous 340
References 343
CHAPTER 27. Vulvodynia 347
References 352
Further reading 353
Appendices 355
Appendix 1: International Society for the Study of Vulvovaginal Disease Classification of Vulvar Disease 357
Vulvar pain 357
Vulvar squamous cell intraepithelial neoplasia 358
Vulvar dermatoses 359
References 360
Appendix 2: Evaluation of Vulvovaginal Disease 361
Making a diagnosis 365
References 367
Further reading 367
Appendix 3: Principles of Therapeutics for Vulvovaginal Disease 369
Nonspecific measures 369
Specific medications 372
Psychoactive medications 376
Reference 377
Appendix 4: Patient Information 379
Desquamative inflammatory vaginitis (Div) 380
Group B streptococcus in the vagina 381
Lichen planus 382
Lichen sclerosus 383
Lichen simplex chronicus (atopic dermatitis, eczema) 384
Physiologic (normal) vaginal discharge 385
vulvodynia and vestibulodynia (vulvar vestibulitis syndrome) 386
Amitriptyline (elavil) 388
Topical corticosteroids (cortisones, steroids) 389
Tips for vulvar skin care 390
Index 391