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Mathematics for the Clinical Laboratory - E-Book

Mathematics for the Clinical Laboratory - E-Book

Lorraine J. Doucette

(2013)

Additional Information

Book Details

Abstract

Mathematics for the Clinical Laboratory is a comprehensive text that teaches you how to perform the clinical calculations used in each area of the laboratory and helps you achieve accurate results. This second edition features even more examples and practice problems. This edition ensures your success by using proven learning techniques focused on practice and repetition to demonstrate how you will use math in the lab every day!

  • New content increases the comprehensiveness of the text
  • Charts and diagrams allow you to picture how calculations work and are applied to laboratory principles
  • Chapter outlines show what to expect from each chapter and how the topics flow and connect to each other
  • Practice problems act as a self-assessment tool to aid in reviewing the material.
  • Significantly updated chapters include calculations that are currently in use in laboratories.
  • More problems and examples applicable to real-life situations have been added to all chapters for additional practice.
  • A companion Evolve website features a test bank, electronic image collection, PowerPoint slides, practice quizzes, additional examples of calculations, and student practice problems.
  • Chapter on the molecular laboratory familiarizes you with the most current information about the critical area of clinical laboratory science.

Table of Contents

Section Title Page Action Price
Front Cover\r Cover
Mathematics for the Clinical Laboratory iii
Copyright\r iv
Reviewers v
Preface vii
Acknowledgments xi
Contents xiii
CHAPTER 1\rBasic Arithmetic, Rounding Numbers, and Significant Figures 1
BASIC ARITHMETIC 2
ROUNDING NUMBERS 18
SIGNIFICANT FIGURES 20
WORKING WITH SIGNIFICANT FIGURES 21
CHAPTER 2 Scientific Notation and Logarithms 32
EXPONENTS AND SCIENTIFIC NOTATION 32
LOGARITHMS 40
CHAPTER 3 \rSystems of Measurement 56
MEASUREMENT OF LENGTH, WEIGHT, AND MASS 56
MEASUREMENT OF TEMPERATURE 66
CHAPTER 4\rDilutions and Titers 75
SIMPLE DILUTIONS 76
DILUTION VARIATIONS 78
DILUTED SPECIMEN VALUES 79
DILUTIONS VERSUS\r RATIOS 80
SERIAL DILUTIONS AND MULTIPLE DILUTIONS 81
TITERS 87
CHAPTER 5 \rMolarity and Normality 94
MOLARITY 94
NORMALITY 104
INTERCONVERSION BETWEEN MOLARITY AND NORMALITY 109
MOLALITY 112
INTERCONVERSION BETWEEN UNITS 115
CHAPTER 6\rCalculations Associated With Solutions 134
PERCENT SOLUTIONS 134
ANHYDROUS VERSUS HYDRATED SOLUTIONS 141
DENSITY CALCULATIONS 142
CONCENTRATION CALCULATIONS 147
CHAPTER 7\rClinical Chemistry Laboratory 158
SPECTROPHOTOMETRY 159
END-POINT VERSUS KINETIC REACTIONS 179
ENZYME KINETICS 179
BUFFER CALCULATIONS 184
ACID-BASE CALCULATIONS 188
ACID-BASE DISORDERS 190
ANION GAP 192
CALCULATED OSMOLALITY AND OSMOLALITY GAP 193
LIPID CALCULATIONS 195
CHAPTER 8\rUrinalysis Laboratory 212
URINE TESTS 212
CORRECTIONS USED FOR THE REFRACTOMETER 213
QUANTITATIVE CHEMICAL ANALYSES 215
RENAL FUNCTION TESTS 218
CHAPTER 9\rHematology Laboratory 230
RULE OF THREE 231
RED BLOOD CELL INDICES 232
CORRECTION OF THE WBC COUNT FOR NUCLEATED RBCs 235
CELL COUNTING BY THE HEMACYTOMETER METHOD 236
BODY FLUIDS 241
RETICULOCYTE COUNT 246
OSMOTIC FRAGILITY 251
INTERNATIONAL NORMALIZED RATIO 252
CHAPTER 10\rImmunohematology Laboratory 264
CALCULATIONS ASSOCIATED WITH THE MEDICAL EFFECTS \nOF TRANSFUSION SERVICES 264
RH INCOMPATIBILITY 268
SCREENING FOR PROBABLE COMPATIBLE UNITS 270
CHAPTER 11\rMicrobiology Laboratory 276
COLONY COUNTS 276
ANTIMICROBIAL SUSCEPTIBILITY TESTING 278
CHAPTER 12\rMolecular Diagnostics Laboratory 284
COMMON UNITS OF MEASUREMENTS USED IN THE CLINICAL MOLECULAR LABORATORY 284
CONVERSIONS COMMONLY PERFORMED IN A CLINICAL MOLECULAR LABORATORY 286
OPTICAL DENSITY TO CONCENTRATION CALCULATIONS 287
MOLECULAR BIOLOGY RESOURCES 290
CHAPTER 13\rQuality Assurance in the Clinical Laboratory: Basic Statistical Concepts 292
MEAN 292
MEDIAN 293
MODE 296
GAUSSIAN DISTRIBUTION 297
ACCURACY VERSUS PRECISION 297
VARIANCE 298
STANDARD DEVIATION 300
PROBABILITIES ASSOCIATED WITH STANDARD DEVIATION 302
ESTABLISHING STANDARD DEVIATION RANGES, STANDARD \nDEVIATION INTERVALS, OR CONFIDENCE INTERVALS 303
COEFFICIENT OF VARIATION 305
CHAPTER 14\rQuality Assurance and Quality Control in the Clinical Laboratory 314
BASIC QUALITY ASSURANCE CONCEPTS 314
WESTGARD MULTIRULES 323
CHAPTER 15\rInstrument and Method Assessment 344
DETERMINATION OF THE DIAGNOSTIC VALUE OF A METHOD 345
CLIA REQUIREMENTS FOR INSTRUMENT/METHOD QUALITY ASSURANCE 350
DETERMINATION OF REPORTABLE RANGE OR LINEARITY OF A METHOD 370
VERIFICATION OF REFERENCE INTERVALS 370
PROFICIENCY TESTING 370
Answer Key 384
Index 397