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Beyond thalidomide

Beyond thalidomide

McCredie, Janet


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How do birth defects happen? Why does thalidomide mutilate the embryo? In this challenging text the author takes a new approach to the resulting disordered anatomy and demonstrates that the skeletal defects seen are inconsistent with primary bone disease, but indicate primary damage to the embryonic sensory nerves - neural crest injury. This book will be of interest to those involved with birth defects - obstetricians, neonatologists, paediatricians - and also neurologists, scientists in teratology and developmental biology, and thalidomiders themselves.