Abstract

The issue of male germ line mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile over recent years. Mutations are thought to be becoming more prevalent as a result of: exposure to chemicals in the environment, anti cancer regimes that use genotoxic agents and assisted conception techniques. In addition to the increasing frequency of mutations in the general population, attention is also being given to the effects of epigenetic events on future generations. Male-mediated Developmental Toxicity discusses these issues comprehensively and includes further analysis on the fundamental mechanisms of mutations. With both clinical and experimental sections, written by leading experts in the field, this book will appeal to both medical practitioners and researchers.
The Editors Professor Diana Anderson currently holds the Established Chair at the Department of Biomedical Sciences at the University of Bradford, UK and is Research Co-ordinator for the Department. Professor Anderson joined BIBRA International in 1981 and in 1992, she became Senior Associate and Co-ordinator of External Affairs at BIBRA. She has over 300 publications, has edited/authored 6 books and guest-edited 9 special issues of 4 international journals. She has is Series Editor of books Issues in Toxicology for the Royal Society of Chemistry. As an active Committee member, she has been Vice-President of the Institute of Biology and is Chair of the Scientific Committee of the International Association of Environmental Mutagen Societies and is a consultant for many international organisations, such as the WHO, NATO, TWAS, UNIDO and the OECD. Dr Martin Brinkworth