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Gynaecology: Prepare for the MRCOG E-book

Gynaecology: Prepare for the MRCOG E-book

Philip N Baker | Alec S. McEwan | Sabaratnam Arulkumaran | Shreelata T Datta | Tahir A Mahmood | Fiona Reid | Mahmood I Shafi | Catherine Aiken

(2015)

Additional Information

Book Details

Abstract

Gynaecology is a new e-book presenting a collection of key articles from Obstetrics, Gynaecology and Reproductive Medicine, mapped by module to the MRCOG Part 2 exam.

As well as mapping to the MRCOG, the Inkling version of this e-book also enables anyone with a short-term interest in a specific area to buy individual articles at a price-point which will give affordable access to all readers (from medical students to GPs and practitioners in related areas, such a genitourinary medicine). Inkling’s app-like quality of user experience on mobiles, tablets and laptops will be an added bonus for learning on the move. As well as being vital preparation for the MRCOG exam, this material is also ideal for life-long learning, CPD and, indeed, preparation for all post-graduate exams in obstetrics (not just MRCOG), including especially the new EBCOG exam in Europe and local college exams in India.[the Middle East and Africa.

The parent journal is a rolling, continuously updated review of gyanecology over a three-year cycle covering all the important topics for the MRCOG Part 2 exam. Its Editorial Board comprises some of Europe’s most influential specialists and includes, among others, the current Presidents of FIGO and EBCOG, as well as the past President of the Royal College of Obstetrics and Gynaecology. The journal’s articles are refreshed, updated, augmented or replaced as appropriate each time the subject is due for revision to provide a concise overview of knowledge and practice core to the curriculum. Each article is written by invited experts and overseen by the relevant subject specialist on the Board. There is a trainee on the Board too, ensuring relevance and accessibility to exam candidates.

  • Inkling version gives a highly attractive, app-like user experience, enabling much easier, more pleasurable use of the content on smartphones, tablets and laptops for learning on the move.
  • Affordable chapter-level purchase on Inkling version opens out the journal’s authority and expertise to all interested users (medical students, family clinicians, genitourinary specialists and all other related specialties).
  • Derived from top-notch authoritative content from the OGRM journal.
  • Overseen by a world-class Editorial Board of experts, which includes the Presidents of FIGO, EBCOG and past President of the RCOG.
  • A trainee representative on the Editorial Board ensures relevance and accessibility for exam candidates.
  • Relevant to all post-graduate exams, including the new EBCOG exam and college exams in India, the Middle East and Africa.
  • Highly appropriate content for life-long learning, personal development portfolios and CPD.

Table of Contents

Section Title Page Action Price
Front Cover\r Cover
Gynaecology: Prepare for the MRCOG Fm-1
Copyright Page Fm-4
Table of Contents Fm-7
Preface Fm-6
About The Obstetrics, Gynaecology and Reproductive Medicine Journal and eBooks Fm-11
Section 1: Benign gynaecology 1
Risk management in gynaecology 1
Introduction 1
Adopt an integrative approach 1
Raise awareness 1
Design for safety 3
Involve service users 4
Collect and analyze patient safety data 4
Learn from patient safety incidents 5
Conclusion 7
Further reading 7
Medico-legal issues in gynaecology 8
Introduction 8
Clinical negligence 8
NHS indemnity 8
CNST 8
Litigation: life-cycle of a claim 9
Burden of claims in gynaecology 9
Causes of claims 9
Reducing the number of incidents 10
When things go wrong 11
Conclusion 12
Further reading 12
The ethics of medical performance 14
Introduction 14
The ethical framework of clinical practice 14
Revalidation 14
The process of revalidation 14
The Role of Royal Medical Colleges in maintaining performance standards 15
Summary and conclusion 15
Further reading 16
Possible reference for other reports of unacceptable performance are: 16
Maternal confidentiality: an ethical, professional and legal duty 17
Introduction 17
The law 17
Professional guidance 17
Ethical arguments 17
Breaching confidentiality 18
Challenges to maintaining patient privacy; traditional and modern problems 18
Conclusion 18
Further reading 18
Ultrasound in obstetrics and gynaecology 20
Introduction 20
How does ultrasound work? 20
Preparation 20
Gynaecological ultrasound 20
Diagnosing malignancy on ultrasound 22
Early pregnancy ultrasound 22
Obstetric ultrasound 23
Conclusion 24
Further reading 24
Perioperative care in gynaecology 26
Introduction 26
Preoperative care 26
Day-case surgery 28
Intraoperative care 28
Postoperative period 29
Discharge 30
Risk management and patient safety 31
Further reading 31
Principles of surgical technique 32
Introduction 32
Fundamental elements of surgical treatment 32
Preoperative evaluation and investigations 32
Anatomy 34
Complications 36
Postoperative care 38
Further reading 39
An overview of hysteroscopy and hysteroscopic surgery 40
Introduction 40
Indications 40
Applications of operative hysteroscopy 40
Theatre set-up 40
Equipment 40
Hysteroscope 40
Principles of electrosurgery needed for operative hysteroscopy using energy 41
Distension media 41
Operative techniques 42
Comparison of endometrial destruction techniques – Cochrane review 2009 43
Comparison of first generation ablation techniques: TCRE, rollerball, laser 43
Pre-operative endometrial preparation and thinning 44
Reproductive hysteroscopic surgery for fibroids 44
Complications 45
Early complications: damage to the uterus or cervix 45
Absorption of distension media 46
Late complications 46
Team work and training 46
Conclusion 46
Further reading 46
Hysterectomy for benign gynaecological disease 48
Introduction 48
Various routes of hysterectomy: outcomes and cost-effectiveness 48
Supracervical hysterectomy/subtotal hysterectomy 49
Robotically assisted hysterectomies 49
Alternatives to hysterectomy and current stand in the United Kingdom 49
Ovarian conservation at hysterectomy 50
Complications of hysterectomy 50
Quality of life and psychological sequelae of hysterectomy 51
The varying hysterectomy rates 51
Health economics of hysterectomy 51
Innovative approaches to hysterectomy 52
Further reading 53
Complications of laparoscopic surgery 54
Introduction 54
Scenario 1: delayed presentation of a bowel injury 54
Case 2: neurological complication from laparoscopic surgery 55
Case 3: management of an intraoperative bladder injury 56
Conclusion 56
Further reading 56
Laparoscopy and laparoscopic surgery 58
Current practice 58
Ectopic pregnancy (Figure 2) 59
Laparoscopic surgery for pelvic organ prolapse 59
Laparoscopic surgery for endometriosis 60
Laparoscopic surgery and infertility management 61
Laparoscopic surgery in gynaecological oncology 61
Litigation and laparoscopic surgery 62
Difficulties with obtaining and maintaining a pneumoperitoneum 63
Injury to bowel when creating pneumoperitoneum or during insertion of trocar 63
Vascular injuries 63
Training 64
Laparoscopic training: virtual reality as an option for the future? 64
Conclusion 65
Further reading 65
Training information 65
Avoiding and managing complications in gynaecological surgery 66
Introduction 66
Predisposing factors 66
Preventing complications 66
Surgical techniques and equipment 67
Recognizing and managing complications 68
Conclusions 71
Further reading 72
Medical and surgical management of chronic pelvic pain 73
Introduction 73
Diagnosis 73
History 73
Examination 74
Investigations 74
Management strategies 74
Conclusions 78
Further reading 78
Heavy menstrual bleeding 80
Introduction 80
Prevalence 80
Causes of heavy menstrual bleeding 80
Obesity and HMB 80
Bleeding of endometrial origin 81
History, examination and investigations for HMB 81
Examination 81
Investigations (Table 2) 81
Treatment for HMB 83
Risks related to various routes for hysterectomy 86
Severe acute heavy menstrual bleeding 87
Further reading 87
Endometriosis 88
Introduction 88
Risk factors and genetics 88
Aetiology 88
Presentation 89
Diagnosis 89
Imaging 90
Surgical management 92
Deep infiltrating endometriosis (DIE) 92
Uterosacral ligaments 92
Rectovaginal septum 93
Bowel 93
Endometriomas 93
Bladder 94
Ureters 95
Presacral neurectomy (PSN) 95
Hysterectomy 95
Conclusion 96
Further Reading 96
Menorrhagia 97
Introduction 97
Definition 97
Aetiology 97
History and examination 97
Investigations 97
Management 97
Further reading 99
Intermenstrual and postcoital bleeding 100
Who should be referred? 100
Further reading 106
Dysmenorrhoea 107
Background 107
Pathophysiology 107
Primary dysmenorrhoea 107
Secondary dysmenorrhoea 108
Clinical features 108
Investigations 109
Management 109
Medical treatments 110
Surgical treatments 111
Conservative treatments 111
Other non-hormonal therapies 112
Prognosis 112
Conclusions 113
Further reading 113
Modern management of fibroids 114
Diagnosis of fibroids 114
Fibroids and fertility 114
Uterine artery embolization 114
Levonorgestrel secreting intrauterine system 117
Progesterone receptor modulators 117
High intensity focused ultrasound 117
Uterine artery occlusion 118
Conclusion 118
Further reading 118
Management of a pelvic mass 120
Introduction 120
Case 1 120
Further case history 120
Case 2 123
Case 3 125
Further reading 126
Non-hormonal contraception 127
Intra-uterine contraception 127
Barrier methods 128
Male condoms 128
Female condoms 128
Diaphragms and caps 129
Spermicides 129
Natural family planning [NFP]/fertility awareness 129
Further reading 129
Non-oral contraception 131
Combined hormonal contraceptives 131
Progestogen only methods – implants and injectables 133
Intrauterine contraception copper intrauterine device (CU-IUD) 134
Barrier methods 135
Further reading 136
Contraception in patients with medical conditions 137
Hypertension 137
Migrainous headaches 140
Venous thromboembolism and hypercoagulable states 140
Further reading 142
Contraception for healthy women 143
Introduction 143
Initial assessment 143
Case 1: contraception for adolescents 143
Case 2: post-partum contraception 145
Case 3: contraception for the perimenopausal period 145
Conclusion 147
Further reading 147
Contraception and its ethical considerations 148
Introduction 148
Clinical assessment 148
Case 1: The adolescent attender 148
Case 2: Comorbidities and the older woman 152
Case 3: A request for permanent contraception 153
Conclusion 154
Further reading 154
Male and female sterilization 156
Introduction 156
Case 1: long term relationship with three children 156
Case 2: young female, new relationship, 4 children 158
Case 3: high BMI with multiple medical problems requesting sterilization 158
Case 4: childless female, tried LARC requesting sterilization 159
Discussion 160
Further reading 160
Intimate partner violence and women's reproductive health 161
Background 161
What are some of the risk factors for intimate partner violence? 161
Dynamics of intimate partner violence and reproductive health 161
Violence and adverse pregnancy outcomes 162
Violence during pregnancy 163
Health outcomes for the women 163
Women's responses to violent relationships 163
What healthcare providers can do about intimate partner violence? 164
Responding to intimate partner violence 165
Policy implications and systems response 167
Appendix 1. Domestic violence screening tool 167
Appendix 2. Example of cue card for healthcare providers responding to intimate partner violence in the UK 168
Further reading 169
Psychosexual problems 170
Introduction 170
Female sexual function 170
Case 1 170
Case 2 171
Female sexual dysfunction classification 171
Case 3 173
Case 4 173
How to ask about sex 174
The examination 174
Case 5 174
Conclusion 175
Further reading 175
Dyspareunia: a difficult symptom in gynaecological practice 176
Introduction 176
Epidemiology 176
Aetiology 176
Common causes 177
History taking 179
Examination 179
Further investigations 180
Conclusions 180
Further reading 181
Sexual assault and rape 182
Introduction 182
Acute assault 182
Recent assault 183
Domestic violence and sexual assault 185
Historic abuse and sexual assault 186
Conclusion 187
Further reading 187
Non-HIV sexually transmitted infections 188
Why are sexually transmitted infections important? 188
Who gets STIs and why? 188
Microscopy, culture, antigen/antibody tests and NAATS 189
General principles of management of STIs 190
Gonorrhoea 190
Syphilis 190
Vaginal discharge 191
Bacterial vaginosis 191
Genital ulcers 191
Other viral infections excluding HIV infection 192
Human papilloma virus 192
Section 2: Subfertility/endocrine\r 261
Investigation and management of recurrent miscarriage 261
Introduction 261
Risks factors 261
Clinical approach 263
Management 264
Further reading 266
Induction of ovulation 267
Introduction 267
Case 1 267
Discussion 267
How to monitor response to treatment 268
Case 2 268
Discussion 268
Complications of gonadotropin treatment 269
Case 3 269
Discussion 269
Conclusions 270
Further reading 270
Preimplantation genetic diagnosis 272
Introduction 272
Technique 272
Clinical applications 272
Outcomes 274
Risks 276
Ethics and controversies 276
Future 278
Further reading 278
Adolescent gynaecology 279
Introduction 279
Menstrual dysfunction 279
Menorrhagia 279
Treatment 279
Acute menorrhagia 280
Dysmenorrhoea 280
Sexually transmitted diseases and pregnancy related problems 280
Disorders of puberty 280
Precocious puberty 281
Premature adrenarche 281
Delayed puberty 281
Amenorrhoea 281
Assessment and investigation 281
Uterine and vaginal causes 282
Ovarian causes 283
Pituitary/hypothalamic causes 284
Conclusion 284
Further reading 284
Management of premenstrual syndrome: evidence-based guidelines 285
Definition 285
Aetiology 285
Prevalence 285
Diagnosis 285
Treatment 286
Medical treatment of PMS 288
Conclusions 291
Key to superscripts 291
Further reading 291
Further information 291
Surgical management of tubal disease and infertility 293
Introduction 293
Causes of tubal disease 293
Assessment of the fallopian tubes 293
Tubal disease and surgery 294
General consideration and patient selection 297
Microsurgical principles 298
Conclusion 298
Further reading 298
Male fertility and infertility 299
Introduction 299
Causes of male infertility 299
Evaluation of male infertility 299
Treatment options for male infertility 301
Further reading 305
Ovarian hyperstimulation syndrome 306
Introduction 306
Pathogenesis 306
Diagnosis 306
Classification 307
Prevention 307
Management 308
Further reading 311
Hirsutism 312
Definition 312
The hair growth cycle 312
Androgen metabolism in the female 312
Aetiology of hirsutism 312
Diagnosis 313
Treatment 314
Further reading 315
Polycystic ovary syndrome: diagnosis and management of related infertility 316
Introduction 316
Historical perspective 316
Pathophysiology 316
Diagnosis 317
Racial difference in expression 317
Signs and symptoms 317
Endocrinological features 318
Ultrasound features of PCOS 318
Management of infertility in PCOS 318
Pharmacological management of infertility in PCOS 319
Surgical management of infertility in PCOS 320
Assisted reproduction techniques: IVF 321
Conclusion 321
Further reading 321
The subfertile couple 323
Case 1 324
What initial advice would you give to this couple? 325
What conditions in Mr PT could produce the unusual clinical and endocrine profiles shown above? 325
What are the effects of anabolic steroids and androgens on fertility? 326
What is the prognosis? 326
Case 3 326
What differential diagnoses should be considered in this woman? 326
Case 4 327
What impact does endometriosis have on reproductive performance? 327
What is the optimal management of ovarian endometriomas? 328
Further reading 328
In vitro fertilization 329
Indications 329
Preparation before treatment 329
Assisted reproduction treatment cycle 330
Ovarian stimulation 331
Ovarian monitoring/final oocyte maturation 332
Oocyte retrieval 333
Laboratory aspects of IVF/ICSI 333
Embryo transfer 333
The technique of embryo transfer 333
Factors affecting the success rate of IVF cycles outcomes 333
Complications of assisted reproduction treatment 334
Multiple pregnancies 335
Other complications 335
Long term safety of IVF 336
Further reading 336
Menstrual dysfunction 338
Introduction 338
The normal menstrual cycle 338
Case 1: abnormal uterine bleeding around the menarche 338
Case 2: ovulatory abnormal uterine bleeding 338
Case 3: anovulatory abnormal uterine bleeding 340
Case 4: abnormal uterine bleeding secondary to uterine fibroids 341
Case 5: abnormal uterine bleeding in the perimenopause 342
Conclusion 342
Further reading 342
Implications of obesity on surgical management of infertility and heavy menstrual bleeding 343
Introduction 343
Fertility 343
Heavy menstrual bleeding 345
Further reading 346
Re-definition and re-classification of menstrual disorders 348
Introduction 348
Normal uterine bleeding 349
Abnormal uterine bleeding 349
Conclusions 352
Further reading 353
Investigation and treatment of primary amenorrhoea 354
Introduction 354
Approach to a patient presenting with primary amenorrhoea 354
Diagnostic workup 355
Evaluation of amenorrhoea 355
Management 355
Turner's syndrome 357
Pure gonadal dysgenesis 357
Swyer syndrome 357
Amenorrhoea of hypothalamic origin 358
Amenorrhoea of pituitary origin 358
Further reading 359
Section 3: Gynaecological oncology\r 360
Colposcopy and cervical intraepithelial neoplasia 360
Introduction 360
Classification of cervical intraepithelial neoplasia 360
Risk factors 360
Natural history of HPV infection 362
Screening 363
Colposcopy 363
Management and treatment 364
Glandular disease 368
Follow-up after treatment 368
HPV vaccines 370
The future 370
Further reading 370
Human papillomavirus update (including vaccination) 371
Background 371
HPV virology 371
Prophylactic HPV vaccination 373
Management of HPV related anogenital neoplasia (AGIN) 374
Future developments 375
Further reading 377
Screening for gynaecological conditions 378
Introduction 378
Gynaecological cancers 378
Screening for non-cancerous conditions 382
Conclusions 382
Further reading 383
Invasive vulval cancer 384
Introduction 384
Predisposing factors 384
Vulval intraepithelial neoplasia (VIN) 384
Human papilloma virus 385
Lichen sclerosis (LS) 385
Lichen planus (LP) 385
Paget's disease 386
Cigarette smoking 386
Squamous cell carcinoma 386
Malignant melanoma 386
Bartholin's gland tumour 386
Basal cell carcinoma 387
Verrucous carcinoma 387
Vulval sarcomas 387
Clinical presentation of vulval cancer 387
Diagnosis and investigations 387
Assessing nodal spread 387
Staging 388
Frailty assessment 388
Management 388
Surgical treatment for early vulval cancer 389
Surgical treatment in advanced disease 390
Management of groin lymph nodes 390
Suspicious/enlarged groin nodes 390
Role of sentinel node dissection 390
Positive groin nodes 391
Radiotherapy 391
Primary radiotherapy 391
Adjuvant radiotherapy 391
Recurrent disease 391
Palliative treatment 391
Quality of life and psychosexual issues 392
Summary 392
Further reading 392
Skin diseases affecting the vulva 393
Infections 393
Disorders associated with malignancy 394
Other inflammatory dermatoses 396
Blisters & ulcers 397
Other conditions affecting the vulva 398
Further reading 398
Principles of chemotherapy and radiotherapy 400
Radiotherapy 400
Chemotherapy 402
Further reading 406
The impact of cancer treatment on reproductive health in young women 407
Introduction 407
Case 1: premature menopause 407
Case 2: primary infertility 408
Measurement of ovarian reserve 408
Case 3: preservation of female fertility 409
Case 4: pregnancy outcome 410
Further reading 410
Current management of gestational trophoblastic disease 412
Introduction 412
Hydatidiform mole 412
GTN 414
Tumours of intermediate trophoblast 420
Further reading 421
Ovarian cancer: current management and future directions 422
Introduction 422
Incidence-mortality 422
Prevention 422
Screening 422
Types of ovarian cancer (Table 3) 423
Epithelial tumours 423
Sex cord-stromal tumours 424
Malignant germ cell tumours 424
Diagnosis 424
Investigations – staging 424
Treatment 425
Surgery 425
Chemotherapy 426
Palliative care 426
Further reading 427
Palliative care in gynaecological oncology 428
Introduction 428
Symptom management 428
Recurrent ascites 431
Genital fistulae 431
Conclusion 432
Further reading 432
Endometrial cancer 434
Introduction 434
Pathology 434
Risk factors 434
Screening 436
Diagnosis 436
Investigations 436
Staging 436
Management 436
Surgical considerations 437
Radiotherapy 437
Chemotherapy 437
Controversies in the management of endometrial cancer 437
Predicting nodal disease 438
Advanced and recurrent disease 438
Endometrial carcinomas in young women 439
Prognosis and follow-up 439
Future directions 439
Further reading 440
Endometrial hyperplasia 441
Introduction 441
Classification 441
Epidemiology 443
Clinical presentation 443
Risk factors 443
Risk of cancer 444
Genetics 444
Investigation 444
Treatment 445
Conclusion 446
Further reading 446
Invasive cancer of the cervix 447
Introduction 447
Epidemiology 447
Pathological subtypes 447
Patterns of spread 447
Clinical management 448
Follow-up 453
Management of recurrent disease 453
Palliation 453
Cervical cancer in pregnancy 453
Prognostic factors 454
Survival 454
Psychological impact 454
The future 454
Further reading 455
Section 4: Urogynaecology & pelvic floor problems \r 456
Assessment of pelvic organ prolapse: a practical guide to the pelvic organ prolapse quantification 456
Introduction 456
Anatomy 456
Definition of prolapse 457
Understanding POP-Q 458
Assessment of symptoms of prolapse 461
Further reading 462
Management of urinary incontinence in frail elderly women 463
Introduction 463
Prevalence 463
Associated factors 463
Conditions caused by urinary incontinence 463
How is continence maintained? 464
Age related changes affecting the urinary tract 465
What are the symptoms and subtypes of UI? 465
Assessment of frail older patients with UI 466
Urinary incontinence and cognitive impairment 469
Conclusion 469
Further reading 469
Painful bladder syndrome 471
Introduction 471
Prevalence 471
Aetiology and pathogesesis 471
Clinical presentation 472
Management 472
Further reading 476
Conservative management of pelvic organ prolapse 477
Introduction 477
Lifestyle advice 477
Pelvic floor muscle training 478
Pessaries 480
Further reading 481
Basic understanding of urodynamics 482
Introduction 482
Background 482
Urodynamic investigations 482
Filling and voiding cystometry – practical points 483
Interpretation 484
After the test 484
Terminology 484
Quality control 484
Troubleshooting 485
Additional urodynamic investigations 486
Setting up equipment 486
Conclusion 487
Further reading 487
Surgical management of stress urinary incontinence 488
Introduction 488
Initial assessment 488
Management of stress urinary incontinence 488
Surgery for stress urinary incontinence 488
Recurrent stress urinary incontinence 492
Conclusion 492
Further reading 493
Modern management of overactive bladder syndrome 494
Introduction 494
Conservative management of OAB 494
Second line management of OAB 494
Further reading 497
Changing trends in pelvic organ prolapse surgery 498
The extent of the problem 498
The changes in POP surgery 498
The evidence for sacral colpopexy 498
Route of sacral colpopexy 499
Sacral colpopexy and uterine prolapse 499
Sacral colpopexy and retropubic surgery 500
Ventral rectopexy 500
Conclusion 501
Further reading 501
Complications of polypropylene mesh in prolapse surgery: an update 503
Introduction 503
Mesh use in the United Kingdom 503
Recent concerns with mesh 503
Efficacy of mesh and mesh kits 503
Complications 504
Specific complications 504
Mesh exposure 504
Mesh infection 506
Mesh contraction 506
Pain and dyspareunia 507
Denovo urinary and faecal incontinence 507
Visceral injury 507
Perioperative haemorrhage 507
Reoperation rates 507
Prolapse of other compartments 507
How to minimize complications 507
Selecting the right mesh 507
Selecting the right surgeon: who should perform mesh surgery? 508
Patient selection 508
Informed consent 508
Selecting the right technique 508
Post procedural follow-up 508
Conclusions 509
Further reading 509
Urological complications following gynaecological surgery 510
Introduction 510
Incidence 510
Risk factors 511
Pathogenesis 511
Prevention of urinary tract injuries 512
Detection of urinary tract injuries 513
Immediate presentation 513
Delayed presentation 513
Management 514
Ureteric injuries 514
Bladder injury 514
Urethral injury 514
Medicolegal implications of urinary tract injuries 514
Conclusion 515
Further reading 515