BOOK
Contribution of FDG to Modern Medicine, Part I, An Issue of PET Clinics, E-Book
(2014)
Additional Information
Book Details
Abstract
This issue of PET Clinics examines the Contribution of FDG to Modern Medicine. In the first of two issues, articles include: The Basic Principles of FDG-PET/CT Imaging; FDG-PET in Diffuse Large B-cell Lymphoma; FDG-PET in Thoracic Malignancies; FDG-PET/CT in Gastrointestinal Malignancies; FDG-PET/CT in Infectious and Inflammatory Diseases; FDG in Urologic Malignancies; FDG-PET for Interventional Oncology in Liver Malignancy; FDG-PET in Neurology and Psychiatry, and more!
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
Contribution of FDG toModern Medicine, Part I\r | i | ||
Copyright\r | ii | ||
Contributors | iii | ||
Contents | v | ||
Pet Clinics\r | viii | ||
Preface\r | xi | ||
The Basic Principles of FDG-PET/CT Imaging | 355 | ||
Key points | 355 | ||
Introduction | 355 | ||
Short historical overview of the early PET evolution | 356 | ||
Basic physics: positron emission and annihilation | 357 | ||
PET-scanner design | 358 | ||
Novel Developments | 360 | ||
PET radionuclides and production of FDG | 360 | ||
The FDG concept | 361 | ||
Cellular Uptake of FDG | 361 | ||
Factors Influencing FDG Uptake | 362 | ||
Correlation Between 18F-FDG Accumulation and the Levels of GLUT, HK, HIF, and Glucose-6-Phosphatase | 362 | ||
Patient preparation, physiologic uptake, and pitfalls | 363 | ||
Concluding remarks | 367 | ||
References | 368 | ||
Fluorodeoxyglucose PET in Neurology and Psychiatry | 371 | ||
Key points | 371 | ||
Introduction | 371 | ||
Imaging technique | 372 | ||
Image Analysis and Data Acquisition | 373 | ||
Normal anatomy | 373 | ||
Imaging findings/pathology | 374 | ||
Dementia | 374 | ||
Alzheimer's disease (AD) | 374 | ||
Frontotemporal dementia (FTD) | 377 | ||
Dementia with lewy bodies (DLB) | 378 | ||
Vascular dementia (VaD) | 379 | ||
Creutzfeldt-Jakob disease (CJD) | 379 | ||
Corticobasal Degeneration (CBD) | 381 | ||
Epilepsy | 382 | ||
Temporal lobe epilepsy | 382 | ||
Extratemporal epilepsy | 383 | ||
Schizophrenia and Bipolar Disorder | 383 | ||
Summary | 384 | ||
Acknowledgments | 384 | ||
References | 384 | ||
[18F]Fluorodeoxyglucose PET in Thoracic Malignancies | 391 | ||
Key points | 391 | ||
Introduction | 391 | ||
Lung nodule characterization | 391 | ||
Staging of non–small cell lung cancer | 394 | ||
N Staging | 394 | ||
M Staging | 396 | ||
New FDG-PET Techniques for Lung Cancer Staging | 398 | ||
Prognostication of clinical outcome in NSCLC | 398 | ||
Dual time-point FDG-PET for evaluation of lung nodules and lung cancer | 399 | ||
Lung Nodule Characterization | 399 | ||
Lung Cancer Staging | 400 | ||
Lung Cancer Tumor Biology and Patient Outcome | 400 | ||
Radiation therapy pretreatment planning and response assessment in NSCLC | 401 | ||
Systemic therapy response assessment in NSCLC | 402 | ||
Restaging of NSCLC | 402 | ||
Other specific thoracic malignancies | 403 | ||
Small Cell Lung Cancer | 403 | ||
Malignant Pleural Mesothelioma | 405 | ||
Esophageal Cancer | 406 | ||
Thymic Epithelial Tumors | 409 | ||
Summary | 411 | ||
References | 411 | ||
[18F]Fluorodeoxyglucose PET/Computed Tomography in Gastrointestinal Malignancies | 421 | ||
Key points | 421 | ||
Introduction | 421 | ||
Gastric cancer | 422 | ||
Introduction | 422 | ||
Staging | 422 | ||
Recurrence Detection | 423 | ||
Response Evaluation, Prognosis, and Impact on Management | 424 | ||
Summary | 424 | ||
Pancreatic cancer | 425 | ||
Introduction | 425 | ||
Initial Diagnosis and Staging | 425 | ||
Recurrence Detection | 426 | ||
Response Evaluation, Prognosis, and Impact on Management | 426 | ||
Summary | 427 | ||
Primary liver malignancies | 427 | ||
Introduction | 427 | ||
Initial Diagnosis and Staging | 427 | ||
Recurrence Detection | 429 | ||
Response Evaluation, Prognosis, and Impact on Management | 429 | ||
Summary | 430 | ||
Colorectal malignancies and liver metastases | 430 | ||
Introduction | 430 | ||
Initial Diagnosis and Staging | 430 | ||
Primary tumor and lymph node staging | 430 | ||
Detection of liver metastases | 431 | ||
Detection of extrahepatic metastases and impact on surgical management | 431 | ||
Recurrence Detection | 432 | ||
Response Assessment and Prognosis | 433 | ||
Summary | 434 | ||
Stroma cell tumors | 434 | ||
Introduction | 434 | ||
Response Assessment and Prognosis | 434 | ||
Summary | 436 | ||
Discussion | 436 | ||
References | 437 | ||
Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Diffuse Large B-cell Lymphoma | 443 | ||
Key points | 443 | ||
Introduction | 443 | ||
FDG–positron emission tomography for initial staging of lymphoma | 443 | ||
FDG–Positron Emission Tomography Versus CT | 443 | ||
FDG-PET in Detection of Bone Marrow Involvement | 444 | ||
FDG-PET in Detecting Extranodal Lesions and Central Nervous System Lymphoma | 446 | ||
FDG-PET and the Use of Dual-time-point PET | 446 | ||
FDG-PET for early response evaluation | 447 | ||
Interpretation of Interim PET Using International Harmonization Project Criteria | 448 | ||
Interpretation of Interim PET Using Deauville 5PS | 448 | ||
Interpretation of Interim PET Using Quantitative Analysis | 449 | ||
FDG-PET for posttreatment evaluation | 449 | ||
FDG-PET for surveillance | 450 | ||
Summary | 450 | ||
References | 451 | ||
FDG in Urologic Malignancies | 457 | ||
Key points | 457 | ||
Introduction | 457 | ||
Frequency of urologic cancers | 457 | ||
Kidney cancer | 458 | ||
Preoperative Use | 459 | ||
Metastatic Disease | 459 | ||
Bladder cancer | 460 | ||
Diagnosis/Staging | 460 | ||
Prostate cancer | 462 | ||
Primary Diagnosis | 462 | ||
Incidental Focal Uptake | 462 | ||
Staging | 464 | ||
Restaging | 465 | ||
Prognostic Value | 466 | ||
Summary | 466 | ||
References | 466 | ||
[18F]Fluorodeoxyglucose PET for Interventional Oncology in Liver Malignancy | 469 | ||
Key points | 469 | ||
Introduction | 469 | ||
Methods | 470 | ||
Results | 470 | ||
Liver Resections | 470 | ||
Preoperative staging | 472 | ||
Intrahepatic disease | 472 | ||
Extrahepatic disease | 474 | ||
Change of management | 474 | ||
Role of FDG-PET in the follow-up | 476 | ||
Role of FDG-PET(/CT) in hepatocellular carcinoma | 477 | ||
Cost-effectiveness | 477 | ||
Summary | 477 | ||
Thermal Ablation Therapy | 478 | ||
Preinterventional staging | 478 | ||
Detection of residual tumor/incomplete ablation | 478 | ||
Early detection of tumor recurrence | 482 | ||
FDG-PET reading | 483 | ||
Role of FDG-PET(/CT) in HCC | 483 | ||
Cost-effectiveness analyses | 483 | ||
Summary | 485 | ||
Radioembolization | 485 | ||
Preinterventional staging | 486 | ||
Posttreatment imaging | 486 | ||
Response assessment and prognostication | 486 | ||
Summary | 488 | ||
Transarterial Chemoembolization | 488 | ||
External-Beam Radiation Therapy | 489 | ||
Discussion | 489 | ||
References | 490 | ||
FDG-PET/CT in Infectious and Inflammatory Diseases | 497 | ||
Key points | 497 | ||
Introduction | 497 | ||
Systemic infections | 497 | ||
Fever and Bacteremia of Unknown Origin | 497 | ||
Immunocompromised Patients | 498 | ||
Infectious Endocarditis | 500 | ||
Bone infections | 502 | ||
Spinal Infection | 502 | ||
Periprosthetic Joint Infections | 503 | ||
Diabetic Foot Infection and Charcot Foot | 503 | ||
Vascular infection and inflammation | 505 | ||
Vascular Graft Infection | 505 | ||
Vasculitis | 506 | ||
Thoracic and abdominal inflammation | 507 | ||
Sarcoidosis | 507 | ||
Inflammatory Bowel Diseases | 509 | ||
Potential novel applications | 510 | ||
Psoriasis and Rheumatoid Arthritis | 510 | ||
Chronic Obstructive Pulmonary Disease | 512 | ||
Venous Thromboembolic Disease | 512 | ||
Concluding remarks | 513 | ||
References | 513 | ||
Index | 521 |