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Mosby's 2015 Nursing Drug Reference - E-Book

Mosby's 2015 Nursing Drug Reference - E-Book

Linda Skidmore-Roth

(2014)

Additional Information

Book Details

Abstract

Find the drug information you need fast! Trusted by nurses for over 25 years, Mosby’s 2015 Nursing Drug Reference features a full-color design and convenient A-to-Z organization that offer quick and easy access to the latest and most vital information on the drugs you administer most frequently. More than 5,000 drugs are profiled and updated in drug monograph format — including 20 new drugs recently approved by the FDA. And no other drug handbook places a higher emphasis on patient safety, with Black Box Warnings for dangerous or life-threatening adverse reactions, Safety Alert icons for situations requiring special attention, and highlighted Common and Life-Threatening Side Effects. Comprehensive coverage also includes IV drug dosage and administration instructions, including special considerations and Y-site, syringe, and additive compatibilities. The companion Evolve website offers even more helpful features, such as additional drug monographs (including infrequently used or recently approved drugs); guidelines to safe handling of chemotherapeutic agents; combination products; controlled-substance chart; drug name safety; drugs metabolized by known P450s; drugs to use cautiously for geriatric patients; herbal products; patient teaching guides in English and Spanish; and Canadian resources.

  • More than 5,000 generic and trade-name drugs are profiled, covering almost every drug you will administer in practice or in clinicals.
  • Attractive full-color design highlights important information for quick and easy access.
  • Black Box Warnings provide alerts to dangerous or life-threatening adverse reactions.
  • Safety Alert icon identifies situations that require special attention.
  • Common and life-threatening side effects are organized by body system, showing signs to watch for during assessments.
  • Nursing Process steps are used as the framework for organizing all nursing care information.
  • Coverage of IV drug administration highlights dosage and IV administration instructions, including special considerations and Y-site, syringe, and additive compatibilities.
  • Comprehensive drug monographs include generic names, Rx or OTC availability, pronunciations, U.S. and Canadian trade names, functional and chemical classification, controlled-substance schedule, do-not-confuse drugs, action, uses, unlabeled uses, dosages and routes, available forms, side effects, contraindications, precautions, pharmacokinetics, interactions (including drug/herb, drug/food and drug lab test), nursing considerations, and treatment of overdose.
  • Complete pharmacokinetic information includes the mechanism and absorption of the drug as well as its action, duration, and excretion.
  • Flexible, water-resistant cover provides durability in the clinical setting.
  • A companion website includes updates with infrequently used or recently approved drugs, a full-color pill atlas, guidelines to safe handling of chemotherapeutic agents, combination products, drugs metabolized by known P450s, medications to be cautiously for geriatric patients, herbal products, a listing of high-alert Canadian medications and immunization schedules, patient teaching guides in English and Spanish, and more.
  • 20 NEW monographs provide current content on added or newly released drugs.

Table of Contents

Section Title Page Action Price
Front cover Cover
How to use ifc
Evolve ifciii
Front matter i
Copyright iv
Consultants v
Preface vi
New features vi
New facts vi
Organization vi
Individual drug monographs vi
Appendixes vii
Table of contents ix
Drug categories e
A e
A 1
Abacavir (Rx) 1
Abatacept (Rx) 2
Abciximab (Rx) 4
Abiraterone 4
Acamprosate 6
Acarbose (Rx) 7
Acetaminophen (OTC) 8
Acetazolamide (Rx) 10
Acetylcholine ophthalmic 13
Acetylcysteine (Rx) 13
Aclidinium 15
Activated charcoal (OTC) 16
Acyclovir (Rx) 17
Adalimumab (Rx) 20
Adefovir (Rx) 22
Adenosine (Rx) 23
Aflibercept 24
Albumin, human 5% (Rx) 26
Albumin, human 25% 26
Albuterol (Rx) 27
Alendronate (Rx) 29
Alfuzosin (Rx) 31
Aliskiren (Rx) 32
Allopurinol (Rx) 33
Almotriptan (Rx) 35
Alogliptin 36
Alosetron 37
Alprazolam (Rx) 38
Controlled substance schedule IV 38
Action: 38
Uses: 38
Contraindications: 39
Dosage and routes 39
Side effects 39
Pharmacokinetics 39
Interactions 39
Nursing considerations 40
Treatment of overdose: 40
Alprostadil (Rx) 40
Alteplase (tissue plasminogen activator, t-PA) (Rx) 41
Aluminum hydroxide (OTC) 43
Alvimopan 44
Amantadine (Rx) 45
Ambrisentan (Rx) 47
Amifostine (Rx) 48
Amikacin (Rx) 50
Amiloride (Rx) 53
Amino acids 55
Amino acid infusions (crystalline) 55
Amino acid infusions/dextrose 55
Aminosyn with electrolytes 55
Amino acid infusions/electrolytes/dextrose 55
Amino acid infusions (hepatic failure) 55
Amino acid infusions (high metabolic stress) 55
Amino acid infusions (renal failure) 55
Amiodarone (Rx) 57
Amitriptyline (Rx) 59
Amlodipine (Rx) 61
Amoxicillin (Rx) 63
Amoxicillin/clavulanate (Rx) 65
Amphotericin B lipid complex (ABLC) 67
Amphotericin B liposomal (LAmB) 69
Ampicillin (Rx) 72
Ampicillin, sulbactam (Rx) 74
Anakinra (Rx) 77
Anastrozole (Rx) 78
Anidulafungin (Rx) 79
Antithymocyte 81
Apomorphine 81
Apraclonidine ophthalmic 83
Aprepitant (Rx) 83
Fosaprepitant 83
Arformoterol (Rx) 85
Argatroban (Rx) 86
Aripiprazole (Rx) 88
Armodafinil (Rx) 90
Controlled substance schedule IV 90
Uses: 90
Contraindications: 90
Dosage and routes 90
Ascorbic acid (vit C) (OTC, Rx) 90
Asenapine (Rx) 92
Asparaginase (Rx) 93
Asparaginase erwinia chrysanthemi 94
Aspirin (OTC) 95
Atazanavir (Rx) 98
Atenolol (Rx) 100
Atomoxetine (Rx) 102
Atorvastatin (Rx) 103
Atovaquone (Rx) 104
Atovaquone/proguanil 105
Atracurium (Rx) 107
Atropine (Rx) 107
Atropine ophthalmic 109
Auranofin (Rx) 109
Avanafil 109
Axitinib 111
Azacitidine (Rx) 113
Azathioprine (Rx) 114
Azelaic acid 116
Azelastine (ophthalmic) 117
Azelastine nasal agent 117
Azilsartan 117
Azithromycin (Rx) 119
Azithromycin ophthalmic 122
Aztreonam (Rx) 122
B e
B 123
Baclofen (Rx) 123
Basiliximab (Rx) 125
Beclomethasone (Rx) 126
Beclomethasone (nasal) 127
Belatacept 128
Belimumab 130
Benazepril (Rx) 132
Bendamustine (Rx) 133
Benzocaine topical 135
Benzonatate (Rx) 135
Benztropine (Rx) 135
Bepotastine 137
Beractant (Rx) 138
Betamethasone (topical) 138
Betamethasone dipropionate 138
Betamethasone augmented dipropionate betamethasone valerate 138
Betamethasone (augmented) topical 139
Betaxolol (ophthalmic) 139
Bethanechol (Rx) 140
Bevacizumab (Rx) 141
Bicalutamide (Rx) 142
Bimatoprost (ophthalmic/topical) 143
Bisacodyl (Rx, OTC) 145
Bismuth subsalicylate (OTC) 146
Bisoprolol (Rx) 147
Bivalirudin (Rx) 149
Bleomycin (Rx) 151
Boceprevir 154
Boric acid otic 156
Bortezomib (Rx) 156
Bosentan (Rx) 158
Bosutinib 159
Brentuximab 161
Brimonidine (ophthalmic) 162
Brinzolamide ophthalmic 163
Bromfenac (ophthalmic) 163
Bromocriptine (Rx) 164
Budesonide (Rx) 166
Budesonide nasal agent 167
Bumetanide (Rx) 168
Buprenorphine (Rx) 170
Controlled substance schedule V (parenteral); schedule III (tablet, TD) 170
Action: 170
Uses: 170
Contraindications: 170
Dosage and routes 170
Side effects 172
Pharmacokinetics 172
Interactions 172
Nursing considerations 172
Treatment of overdose: 173
Bupropion (Rx) 173
Buspirone (Rx) 175
Busulfan (Rx) 176
Butoconazole vaginal antifungal 179
Butorphanol (Rx) 179
Controlled substance schedule IV 179
Action: 179
Uses: 179
Contraindications: 179
Dosage and routes 179
Side effects 180
Pharmacokinetics 180
Interactions 180
Nursing considerations 180
Treatment of overdose: 181
C e
C 182
Cabozantinib 182
Calcitonin (rDNA) (Rx) 183
Calcitonin (salmon) (Rx) 183
Calcitriol vitamin D3 (Rx) 184
Calcium carbonate (PO-OTC) 186
Calcium acetate (OTC) 186
Calcium chloride (Rx) 188
Calcium gluceptate (Rx) 188
Calcium gluconate (Rx) 188
Calcium lactate (Rx) 188
Calfactant (Rx) 190
Candesartan (Rx) 190
Capecitabine (Rx) 192
Captopril (Rx) 194
Carbachol ophthalmic 196
Carbamazepine (Rx) 196
Carboplatin (Rx) 199
Carboprost (Rx) 202
Carfilzomib 203
Carglumic acid 204
Carisoprodol (Rx) 205
Controlled substance schedule IV 205
Action: 205
Uses: 205
Contraindications: 205
Dosage and routes 205
Side effects 205
Pharmacokinetics 206
Interactions 206
Nursing considerations 206
Treatment of overdose: 206
Carmustine (Rx) 206
Carteolol (ophthalmic) 208
Carvedilol (Rx) 210
Caspofungin (Rx) 212
Cefaclor 213
Cefadroxil 213
Cefazolin 213
Cefdinir 213
Cefditoren pivoxil 213
Cefepime 213
Cefixime 213
Cefotaxime 213
Cefotetan 213
Cefoxitin 213
Cefpodoxime 213
Cefprozil 213
Ceftazidime 213
Ceftibuten 213
Ceftizoxime 213
Ceftriaxone 213
Cefuroxime 213
Ceftaroline (Rx) 214
Celecoxib (Rx) 215
Cephalexin 217
Cefadroxil (Rx) 217
Cefazolin (Rx) 217
Cephalexin (Rx) 217
Cefaclor (Rx) 220
Cefotetan (Rx) 220
Cefoxitin (Rx) 220
Cefprozil (Rx) 220
Cefuroxime (Rx) 220
Cefdinir (Rx) 224
Cefditoren pivoxil (Rx) 224
Cefepime (Rx) 224
Cefixime (Rx) 224
Cefotaxime (Rx) 224
Cefpodoxime (Rx) 224
Ceftazidime (Rx) 224
Ceftibuten (Rx) 224
Ceftizoxime (Rx) 224
Ceftriaxone (Rx) 224
Cephradine 234
Certolizumab pegol (Rx) 234
Cetirizine (Rx, OTC) 235
Cetrorelix (Rx) 237
Cetuximab (Rx) 238
Chlordiazepoxide (Rx) 239
Controlled substance schedule IV 239
Action: 239
Uses: 239
Contraindications: 239
Dosage and routes 240
Side effects 240
Pharmacokinetics 240
Interactions 240
Nursing considerations 240
Treatment of overdose: 241
Chloroquine (Rx) 241
Chlorpheniramine (OTC, Rx) 243
Chlorpromazine (Rx) 244
Cholestyramine (Rx) 247
Cidofovir (Rx) 248
Cilostazol (Rx) 250
Cimetidine (OTC, Rx) 252
Cinacalcet (Rx) 254
Ciprofloxacin (Rx) 255
Ciprofloxacin (ophthalmic) 258
Cisatracurium 259
Cisplatin (Rx) 260
Citalopram (Rx) 263
Clarithromycin (Rx) 265
Clevidipine (Rx) 267
Clindamycin HCI (Rx) 268
Clindamycin palmitate (Rx) 268
Clindamycin phosphate (Rx) 268
Clindamycin (topical, vaginal) 271
Clobetasol 273
Clomiphene (Rx) 274
Clomipramine (Rx) 275
Clonazepam (Rx) 277
Controlled substance schedule IV 277
Action: 277
Uses: 277
Contraindications: 277
Dosage and routes 277
Side effects 277
Pharmacokinetics 278
Interactions 278
Nursing considerations 278
Treatment of overdose: 278
Clonidine (Rx) 279
Clopidogrel (Rx) 281
Clotrimazole (topical, vaginal, oral) 282
Clozapine (Rx) 283
Codeine (Rx) 286
Controlled substance schedule II, III, IV, V (depends on content) 286
Action: 286
Uses: 286
Contraindications: 286
Dosage and routes 286
Side effects 287
Pharmacokinetics 287
Interactions 287
Nursing considerations 287
Treatment of overdose: 287
Colchicine (Rx) 288
Colesevelam (Rx) 289
Conivaptan (Rx) 290
Contraceptives, hormonal 292
Crizotinib 295
Cromolyn (OTC, Rx) 298
Crotamiton 299
Cyanocobalamin (vit B12) (OTC, Rx) 300
Hydroxocobalamin (OTC, Rx) 300
Cyclobenzaprine (Rx) 302
Cyclopentolate ophthalmic 303
Cyclophosphamide (Rx) 303
Cyclosporine (Rx) 307
Cytarabine (Rx) 310
Cytarabine liposomal (Rx) 310
D e
D 314
Dabigatran 314
Dacarbazine (Rx) 315
Dalfampridine (Rx) 317
Dalteparin (Rx) 318
Dantrolene (Rx) 319
Dapiprazole ophthalmic 321
Daptomycin (Rx) 321
Darbepoetin (Rx) 323
Darifenacin 325
Darunavir (Rx) 326
Dasatinib (Rx) 328
Daunorubicin (Rx) 329
Daunorubicin citrate liposomal (Rx) 329
Deferasirox (Rx) 332
Degarelix 332
Delavirdine (Rx) 334
Demecarium ophthalmic 335
Denosumab (Rx) 335
Desipramine (Rx) 337
Desirudin 339
Desloratadine (Rx) 340
Desmopressin (Rx) 341
Desonide topical 342
Desoximetasone 342
Desoxyephedrine nasal agent 343
Desvenlafaxine 343
Dexamethasone (Rx) 345
Dexamethasone sodium phosphate (Rx) 345
Dexamethasone (ophthalmic) 348
Dexamethasone topical 349
Dexlansoprazole (Rx) 349
Dexmethylphenidate (Rx) 350
Controlled substance schedule II 350
Action: 350
Uses: 350
Contraindications: 350
Dosage and routes 350
Side effects 351
Pharmacokinetics 351
Interactions 351
Nursing considerations 351
Treatment of overdose: 352
Dextroamphetamine (Rx) 352
Controlled substance schedule II 352
Action: 352
Uses: 352
Contraindications: 352
Dosage and routes 352
Side effects 352
Pharmacokinetics 352
Interactions 353
Nursing considerations 353
Treatment of overdose: 353
Dextromethorphan (OTC) 354
Dextrose (D-glucose) (Rx) 355
Diazepam (Rx) 356
Controlled substance schedule IV 356
Action: 356
Uses: 356
Contraindications: 356
Dosage and routes 356
Side effects 357
Pharmacokinetics 357
Interactions 357
Nursing considerations 357
Treatment of overdose: 358
Dibucaine topical 358
Diclofenac epolamine (Rx) 358
Diclofenac potassium (Rx) 358
Diclofenac sodium (Rx) 358
Diclofenac ophthalmic 361
Dicyclomine (Rx) 361
Didanosine (Rx) 361
Diflunisal 363
Difluprednate (ophthalmic) 364
Digoxin (Rx) 364
Digoxin immune FAB (ovine) (Rx) 370
Diltiazem (Rx) 371
Dimenhydrinate (OTC, Rx) 373
Motion sickness 373
Dinoprostone (Rx) 374
Diphenhydramine (OTC, Rx) 375
Diphenoxylate/atropine (Rx) 378
Difenoxin/atropine (Rx) 378
Controlled substance schedule V 378
Controlled substance schedule IV 378
Action: 378
Uses: 378
Contraindications: 378
Dosage and routes 378
Side effects 378
Pharmacokinetics 378
Interactions 378
Nursing considerations 379
Dipivefrin ophthalmic 379
Dipyridamole (Rx) 379
Dobutamine (Rx) 380
Docetaxel (Rx) 382
Docosanol topical 385
Docusate calcium (OTC) 386
Docusate sodium (OTC) 386
Dofetilide (Rx) 387
Dolasetron (Rx) 388
Donepezil (Rx) 390
Dopamine (Rx) 391
Doripenem (Rx) 393
Dorzolamide (ophthalmic) 395
Doxapram (Rx) 396
Doxazosin (Rx) 397
Doxepin (Rx) 399
Doxorubicin 401
Doxorubicin liposomal 403
Doxycycline (Rx) 406
Doxycycline calcium 406
Doxycycline hyclate 406
Doxycycline monohydrate 406
Dronedarone (Rx) 409
Droperidol (Rx) 411
Duloxetine (Rx) 412
Dutasteride (Rx) 414
E e
E 416
Ecallantide 416
Econazole 416
Econazole topical 417
Ecothiophate ophthalmic 417
Edetate calcium disodium (Rx) 417
Efavirenz (Rx) 418
Eletriptan (Rx) 419
Eltrombopag 420
Emedastine ophthalmic 420
Emtricitabine (Rx) 421
Enalapril/enalaprilat (Rx) 422
Enfuvirtide (Rx) 424
Enoxaparin (Rx) 426
Entacapone (Rx) 428
Entecavir (Rx) 429
Enzalutamide 430
Ephedrine nasal agent 431
Epinastine (ophthalmic) 431
Epinephrine (Rx) 432
Epinephrine HCL 432
Epinephrine/epinephryl borate ophthalmic 435
Epinephrine nasal agent 435
Epirubicin (Rx) 435
Eplerenone (Rx) 439
Epoetin alfa (Rx) 440
Eprosartan (Rx) 442
Eptifibatide (Rx) 444
Eribulin 445
Erlotinib (Rx) 447
Ertapenem (Rx) 449
Erythromycin 451
Erythromycin base (Rx) 452
Erythromycin ethylsuccinate (Rx) 452
Erythromycin lactobionate (Rx) 452
Erythromycin stearate (Rx) 452
Erythromycin (topical) 456
Escitalopram (Rx) 457
Esmolol (Rx) 459
Esomeprazole (Rx) 461
Estradiol (Rx) 462
Estradiol cypionate (Rx) 462
Estradiol gel (Rx) 462
Estradiol spray (Rx) 462
Estradiol topical emulsion (Rx) 462
Estradiol valerate (Rx) 462
Estradiol transdermal system (Rx) 462
Estradiol vaginal tablet (Rx) 462
Estradiol vaginal ring (Rx) 462
Estramustine (Rx) 465
Estrogens, conjugated (Rx) 465
Estrogens, conjugated synthetic B (Rx) 465
Estropipate 467
Eszopiclone (Rx) 467
Controlled substance schedule IV 467
Action: 467
Uses: 467
Contraindications: 467
Dosage and routes 467
Side effects 468
Pharmacokinetics 468
Interactions 468
Nursing considerations 468
Etanercept (Rx) 468
Ethambutol (Rx) 471
Etodolac 472
Etomidate (Rx) 473
Etoposide (Rx) 474
Etoposide phosphate (Rx) 474
Etravirine (Rx) 477
Everolimus (Rx) 479
Exemestane (Rx) 481
Exenatide (Rx) 482
Ezetimibe (Rx) 484
Ezogabine 484
F e
F 487
Factor IX complex (human) (Rx) 487
Famciclovir (Rx) 488
Famotidine (OTC, Rx) 489
Fat emulsions (Rx) 492
Febuxostat (Rx) 493
Felodipine (Rx) 494
Fenofibrate (Rx) 495
Fentanyl (Rx) 497
Fentanyl transdermal (Rx) 497
Fentanyl nasal spray (Rx) 497
Fentanyl SL spray 497
Controlled substance schedule II 497
Action: 497
Uses: 497
Contraindications: 497
Dosage and routes 497
Fentanyl 497
Anesthetic 497
G e
G 552
Gabapentin (Rx) 552
Galantamine (Rx) 554
Ganciclovir (Rx) 555
Ganciclovir ophthalmic 557
Gatifloxacin 557
Gefitinib (Rx) 558
Gemcitabine (Rx) 559
Gemfibrozil (Rx) 561
Gemifloxacin (Rx) 562
Gentamicin (Rx) 564
Gentamicin (ophthalmic) 567
Gentamicin (topical) 567
Glatiramer (Rx) 568
Glimepiride (Rx) 569
Glipizide (Rx) 569
Glucagon 571
Glucarpidase 572
Glyburide (Rx) 573
Glycerin (OTC) 575
Golimumab (Rx) 575
Goserelin (Rx) 577
Granisetron (Rx) 578
Guaifenesin (OTC, Rx) 580
H e
H 581
Halcinonide topical 581
Haloperidol (Rx) 581
Haloperidol decanoate (Rx) 581
Haloperidol lactate (Rx) 581
Heparin (Rx) 583
Hepatitis B immune globulin (HBIG) (Rx) 586
Homatropine ophthalmic 587
Hydralazine (Rx) 587
Hydrochlorothiazide (Rx) 589
Hydrocodone (Rx) 590
Hydrocodone/acetaminophen (Rx) 590
Hydrocodone/ibuprofen (Rx) 590
Controlled substance schedule III 590
Action: 590
Uses: 590
Contraindications: 590
Dosage and routes 591
Side effects 591
Pharmacokinetics 591
Interactions 591
Nursing considerations 591
Treatment of overdose: 592
Hydrocortisone (Rx) 592
Hydrocortisone acetate (Rx) 592
Hydrocortisone sodium succinate (Rx) 592
Hydrocortisone nasal 594
Hydrocortisone (topical) 595
Hydrocortisone acetate 595
Hydrocortisone butyrate 595
Hydrocortisone probutate 595
Hydrocortisone valerate 595
Hydromorphone (Rx) 596
Controlled substance schedule II 596
Action: 596
Uses: 596
Contraindications: 596
Dosage and routes 596
Side effects 597
Pharmacokinetics 597
Interactions 598
Nursing considerations 598
Treatment of overdose: 598
Hydroxychloroquine (Rx) 598
Hydroxyurea (Rx) 600
Hydroxyzine (Rx) 602
Hyoscyamine (Rx) 603
I e
I 605
Ibandronate (Rx) 605
Ibritumomab (Rx) 606
Ibuprofen (OTC, Rx) 608
Ibuprofen lysine (Rx) 608
Ibutilide (Rx) 610
Icosapent 611
Idarubicin (Rx) 612
Ifosfamide (Rx) 614
Iloperidone (Rx) 616
Imatinib (Rx) 618
Imipenem/cilastatin (Rx) 621
Imipramine (Rx) 624
Immune globulin IM (IMIG/IGIM) (Rx) 626
Immune globulin IV (IGIV, IVIG) (Rx) 626
Immune globulin SC (SCIG/IGSC) 626
Indacaterol 628
Indapamide (Rx) 630
Indinavir (Rx) 631
Indomethacin (Rx) 633
Infliximab (Rx) 635
Insulins 636
Rapid acting 636
Insulin glulisine (Rx) 636
Insulin aspart (Rx) 636
Insulin lispro (Rx) 636
Short acting 636
Insulin, regular (OTC) 636
Insulin, regular concentrated (Rx) 636
Intermediate acting 636
Insulin, isophane suspension (NPH) (OTC) 636
Long acting 636
Insulin detemir (Rx) 636
Insulin glargine (Rx) 636
Mixtures 637
Insulin, isophane suspension and regular insulin (Rx) 637
Isophane insulin suspension (NPH) and insulin mixtures (Rx) 637
Insulin lispro mixture (Rx) 637
Insulin aspart mixture (Rx) 637
Interferon alfacon-1 (Rx) 640
Interferon beta-1a (Rx) 641
Interferon beta-1b (Rx) 641
Interferon gamma-1b (Rx) 646
Ipilimumab 647
Ipratropium (Rx) 648
Irbesartan (Rx) 649
Irinotecan (Rx) 651
Iron dextran (Rx) 653
Iron sucrose (Rx) 654
Isoflurophate ophthalmic 655
Isoniazid (Rx) 655
Isosorbide dinitrate (Rx) 657
Isosorbide mononitrate (Rx) 657
Isotretinoin (Rx) 658
Itraconazole (Rx) 658
Ivacaftor 660
Ixabepilone (Rx) 660
K e
K 663
Ketoconazole (Rx) 663
Ketoconazole (topical) 664
Ketoprofen (OTC, Rx) 665
Ketorolac (ophthalmic) 667
Ketorolac (systemic, nasal) (Rx) 668
Ketotifen (ophthalmic) 670
L e
L 672
Labetalol (Rx) 672
Lacosamide (Rx) 674
Lactulose (Rx) 676
Lamivudine 3TC (Rx) 677
Lamotrigine (Rx) 678
Lansoprazole (Rx, OTC) 680
Lanthanum (Rx) 682
Lapatinib (Rx) 682
Latanoprost (ophthalmic) 684
Leflunomide (Rx) 685
Letrozole (Rx) 686
Leucovorin (Rx) 687
Leuprolide (Rx) 689
Levalbuterol (Rx) 691
Levetiracetam (Rx) 693
Levobetaxolol ophthalmic 694
Levobunolol (ophthalmic) 694
Levocabastine ophthalmic 695
Levocetirizine (Rx) 695
Levodopa-carbidopa (Rx) 696
Levofloxacin (Rx) 698
Levofloxacin ophthalmic 702
Levothyroxine (T4) (Rx) 702
Lidocaine (parenteral) (Rx) 704
Lidocaine topical 705
Linaclotide 706
Linagliptin 706
Lindane (Rx) 708
Linezolid (Rx) 709
Liothyronine (T3) (Rx) 711
Liotrix (Rx) 713
Liraglutide (Rx) 714
Lisdexamfetamine (Rx) 716
Controlled substance schedule II 716
Action: 716
Uses: 716
Contraindications: 716
Dosage and routes 716
Side effects 716
Pharmacokinetics 716
Interactions 716
Nursing considerations 717
Treatment of overdose: 717
Lisinopril (Rx) 717
Lithium (Rx) 719
Lodoxamide ophthalmic 721
Loperamide (OTC, Rx) 721
Lopinavir/ritonavir 722
Loratadine (OTC, Rx) 724
Lorazepam (Rx) 725
Controlled substance schedule IV 725
Action: 725
Uses: 725
Contraindications: 725
Dosage and routes 725
Side effects 726
Pharmacokinetics 727
Interactions 727
Nursing considerations 727
Treatment of overdose: 727
Lorcaserin 727
Losartan 728
Loteprednol ophthalmic 730
Lovastatin (Rx) 730
Loxapine (Rx) 731
Lubiprostone (Rx) 734
Lucinactant 735
Lurasidone (Rx) 735
Lymphocyte immune globulin (anti-thymocyte, equine) (Rx) 736
M e
M 738
Mafenide topical 738
Magnesium salts 738
Magnesium chloride (Rx) 738
Magnesium citrate (OTC) magnesium gluconate (OTC) 738
Magnesium oxide (OTC) 738
Magnesium hydroxide (OTC) 738
Magnesium sulfate (OTC, Rx) 738
Mannitol (Rx) 740
Maraviroc (Rx) 742
Mebendazole (Rx) 743
Mecasermin (Rx) 744
Meclizine (OTC, Rx) 746
Medroxyprogesterone (Rx) 747
Medrysone ophthalmic 749
Megestrol (Rx) 749
Melphalan (Rx) 750
Memantine (Rx) 752
Meperidine (Rx) 754
Controlled substance schedule II 754
Action: 754
Uses: 754
Contraindications: 754
Dosage and routes 754
Side effects 755
Pharmacokinetics 755
Interactions 755
Nursing considerations 755
Treatment of overdose: 756
Mercaptopurine (6-MP) (Rx) 756
Meropenem (Rx) 758
Mesalamine, 5-ASA (Rx) 760
Metformin (Rx) 761
Methadone (Rx) 763
Controlled substance schedule II 763
Action: 763
Uses: 764
Contraindications: 764
Dosage and routes 764
Side effects 764
Pharmacokinetics 764
Interactions 764
Nursing considerations 765
Treatment of overdose: 765
Methimazole (Rx) 765
Methotrexate (Rx) 767
Methylcellulose (OTC) 771
Methyldopa/methyldopate (Rx) 771
Methylergonovine (Rx) 774
Methylnaltrexone (Rx) 775
Methylphenidate (Rx) 776
Controlled substance schedule II 776
Action: 776
Uses: 776
Contraindications: 776
Dosage and routes 776
Side effects 777
Pharmacokinetics 778
Interactions 778
Nursing considerations 778
Treatment of overdose: 778
Methylprednisolone (Rx) 779
Metipranolol ophthalmic 781
Metoclopramide (Rx) 781
Metolazone (Rx) 784
Metoprolol (Rx) 785
Metronidazole (Rx) 788
Metronidazole (topical, vaginal) 791
Micafungin (Rx) 792
Miconazole 794
Miconazole nitrate 794
Midazolam (Rx) 795
Controlled substance schedule IV 795
Action: 795
Uses: 795
Contraindications: 795
Dosage and routes 796
Side effects 797
Pharmacokinetics 797
Interactions 797
Nursing considerations 797
Treatment of overdose: 797
Miglitol (Rx) 797
Milrinone (Rx) 798
Minocycline (Rx) 800
Minoxidil (Rx, OTC) 802
Mirabegron 804
Mirtazapine (Rx) 805
Misoprostol (Rx) 806
Mitomycin (Rx) 807
Mitoxantrone (Rx) 809
Modafinil (Rx) 812
Controlled substance IV 812
Action: 812
Uses: 812
Contraindications: 812
Dosage and routes 812
Side effects 812
Pharmacokinetics 812
Interactions 812
Nursing considerations 812
Montelukast (Rx) 813
Morphine (Rx) 814
Controlled substance schedule II 814
Action: 814
Uses: 814
Contraindications: 814
Dosage and routes 815
Side effects 817
Pharmacokinetics 818
Interactions 818
Nursing considerations 818
Treatment of overdose: 818
Moxifloxacin (Rx) 818
Moxifloxacin (ophthalmic) 821
Mupirocin (topical, nasal) 821
Mycophenolate mofetil (Rx) 822
N e
N 825
Nabumetone (Rx) 825
Nadolol (Rx) 826
Nafcillin (Rx) 828
Nalbuphine (Rx) 830
Naloxone (Rx) 831
Naltrexone (Rx) 833
Naphazoline nasal agent 834
Naphazoline (ophthalmic) 835
Naproxen (Rx, OTC) 835
Naratriptan (Rx) 837
Natalizumab (Rx) 838
Natamycin ophthalmic 840
Nebivolol (Rx) 840
Nelfinavir ( Rx) 842
Neomycin (Rx) 843
Neomycin topical 844
Nepafenac ophthalmic 844
Nesiritide (Rx) 844
Nevirapine (Rx) 845
Niacin (OTC, Rx) 847
Niacinamide (OTC, Rx) 847
Nicardipine (Rx) 849
Nicotine 851
Nicotine chewing gum 851
Nicotine inhaler (OTC, Rx) 851
Nicotine lozenge (OTC) 851
Nicotine nasal spray (Rx) 851
Nicotine transdermal (OTC, Rx) 851
Nifedipine (Rx) 853
Nilotinib (Rx) 855
Nisoldipine (Rx) 856
Nitazoxanide (Rx) 858
Nitrofurantoin (Rx) 858
Nitrofurazone topical 860
Nitroglycerin (Rx) 860
Extended release caps (Rx) 860
Topical ointment (Rx) 860
Rectal ointment 860
SL (Rx) 860
Translingual spray (Rx) 860
Transdermal (Rx) 860
Nitroprusside (Rx) 863
Nizatidine (OTC, Rx) 865
Norepinephrine (Rx) 866
Norethindrone (Rx) 868
Norfloxacin ophthalmic 869
Nortriptyline (Rx) 869
Nystatin (Rx) 871
Nystatin topical 872
Nystatin vaginal antifungal 872
O e
O 873
Ocriplasmin 873
Octreotide (Rx) 873
Ofloxacin (Rx) 875
Ofloxacin ophthalmic 877
Olanzapine (Rx) 877
Olmesartan (Rx) 880
Olopatadine nasal agent 881
Olopatadine ophthalmic 881
Olsalazine (Rx) 881
Omacetaxine 882
Omalizumab (Rx) 883
Omeprazole (OTC, Rx) 884
Ondansetron (Rx) 886
Orlistat (Rx, OTC) 888
Oseltamivir (Rx) 889
Oxaliplatin (Rx) 890
Oxazepam (Rx) 893
Controlled substance schedule IV 893
Action: 893
Uses: 893
Contraindications: 893
Dosage and routes 893
Side effects 893
Pharmacokinetics 894
Interactions 894
Nursing considerations 894
Oxcarbazepine (Rx) 894
Oxybutynin (Rx, OTC) 896
Oxycodone (Rx) 898
Oxycodone/aspirin (Rx) 898
Oxycodone/acetaminophen (Rx) 898
Oxycodone/ibuprofen (Rx) 898
Controlled substance schedule II 898
Action: 898
Uses: 898
Contraindications: 898
Dosage and routes 898
Side effects 899
Pharmacokinetics 899
Interactions 899
Nursing considerations 899
Treatment of overdose: 900
Oxymetazoline nasal agent 900
Oxymetazoline ophthalmic 900
Oxymorphone (Rx) 900
Controlled substance schedule II 900
Action: 900
Uses: 900
Contraindications: 900
Dosage and routes 900
Side effects 901
Pharmacokinetics 901
Interactions 901
Nursing considerations 901
Treatment of overdose: 902
Oxytocin (Rx) 902
P e
P 904
Paclitaxel (Rx) 904
Paclitaxel nanoparticle albumin-bound (Rx) 904
Paliperidone (Rx) 906
Palonosetron (Rx) 909
Pamidronate (Rx) 910
Pancrelipase (Rx) 913
Pancuronium (Rx) 914
Panitumumab (Rx) 915
Pantoprazole (Rx) 916
Paricalcitol (Rx) 919
Paroxetine (Rx) 920
Pazopanib 922
Pegfilgrastim (Rx) 923
Peginterferon alfa-2a (Rx) 924
Peginterferon alfa-2b (Rx) 924
Pegloticase (Rx) 926
Pemetrexed (Rx) 928
Penciclovir topical 930
Penicillin G benzathine (Rx) 930
Penicillin G (Rx) 930
Penicillin G procaine (Rx) 930
Penicillin V (Rx) 930
Pentamidine (Rx) 933
Pentazocine (Rx) 935
Controlled substance schedule IV 935
Action: 935
Uses: 935
Contraindications: 935
Dosage and routes 935
Side effects 935
Pharmacokinetics 935
Interactions 936
Nursing considerations 936
Treatment of overdose: 936
Pentoxifylline (Rx) 936
Perampanel 937
Perindopril (Rx) 938
Pertuzumab 940
Phenobarbital (Rx) 941
Controlled substance schedule IV 941
Action: 941
Uses: 941
Contraindications: 942
Dosage and routes 942
Side effects 942
Pharmacokinetics 942
Interactions 942
Nursing considerations 943
Phentolamine (Rx) 943
Phenylephrine (Rx) 944
Phenylephrine nasal agent 946
Phenylephrine ophthalmic 946
Phenytoin (Rx) 946
Phosphate/biphosphate (OTC) 948
Physostigmine ophthalmic 949
Phytonadione (Rx) 949
Pilocarpine ophthalmic 950
Pimecrolimus topical 951
Pioglitazone (Rx) 951
Piperacillin/tazobactam (Rx) 952
Pirbuterol (Rx) 955
Pitavastatin (Rx) 956
Plasma protein fraction (Rx) 957
Plerixafor (Rx) 958
Posaconazole (Rx) 959
Potassium acetate 961
Potassium bicarbonate (OTC, Rx) 961
Potassium bicarbonate and potassium chloride (OTC, Rx) 961
Potassium bicarbonate and potassium citrate (OTC, Rx) 961
Potassium chloride (OTC, Rx) 961
Potassium gluconate (OTC, Rx) 961
Potassium iodide (Rx) 963
Pramipexole (Rx) 964
Pramlintide (Rx) 965
Pramoxine topical 967
Prasugrel (Rx) 967
Pravastatin (Rx) 968
Prazosin (Rx) 969
Prednisolone (Rx) 971
Prednisolone ophthalmic (Rx) 973
Prednisone (Rx) 973
Pregabalin (Rx) 975
Controlled substance schedule V 975
Action: 975
Uses: 975
Contraindications: 975
Dosage and routes 976
Side effects 976
Pharmacokinetics 976
Interactions 976
Nursing considerations 976
Treatment of overdose: 977
Primaquine (Rx) 977
Primidone (Rx) 978
Probenecid (Rx) 980
Procainamide (Rx) 981
Procarbazine (Rx) 983
Prochlorperazine (Rx) 985
Progesterone (Rx) 987
Promethazine (Rx) 988
Propafenone (Rx) 991
Proparacaine ophthalmic 992
Propofol (Rx) 992
Propranolol (Rx) 994
Propylhexadrine nasal agent 997
Propylthiouracil (Rx) 998
Protamine (Rx) 999
Pseudoephedrine (OTC, Rx) 1000
Pseudoephedrine nasal agent 1001
Psyllium (OTC, Rx) 1002
Pyridostigmine (Rx) 1002
Pyridoxine (vit B6) (Rx, OTC) 1004
Pyrimethamine (Rx) 1005
Q e
Q 1007
Quetiapine (Rx) 1007
Quinapril (Rx) 1009
Quinidine gluconate (Rx) 1010
Quinidine sulfate (Rx) 1010
R e
R 1014
Rabeprazole (Rx) 1014
Radioactive iodine (sodium iodide) 131I (Rx) 1015
Raloxifene (Rx) 1016
Raltegravir (Rx) 1018
Ramelteon (Rx) 1019
Ramipril (Rx) 1020
Ranibizumab (Rx) 1022
Ranitidine (Rx, OTC) 1023
Ranitidine bismuth citrate 1023
Ranolazine (Rx) 1025
Rasagiline (Rx) 1027
Rasburicase (Rx) 1028
Regorafenib 1029
Remifentanil (Rx) 1031
Controlled substance schedule II 1031
Action: 1031
Uses: 1031
Contraindications: 1031
Dosage and routes 1031
Side effects 1032
Pharmacokinetics 1032
Interactions 1032
Nursing considerations 1032
Repaglinide (Rx) 1032
Retapamulin (topical) 1034
Rho(D) immune globulin standard dose IM (Rx) 1034
Rho(D) immune globulin microdose IM (Rx) 1034
Rho(D) immune globulin IV (Rx) 1034
Riboflavin (vit B2) (OTC) 1036
Rifabutin (Rx) 1037
Rifampin (Rx) 1038
Rifapentine (Rx) 1040
Rifaximin (Rx) 1042
Rilpivirine 1043
Riluzole (Rx) 1044
Rimantadine (Rx) 1045
Rimexolone ophthalmic 1046
Risedronate (Rx) 1046
Risperidone (Rx) 1048
Ritonavir (Rx) 1052
Rituximab (Rx) 1053
Rivaroxaban 1056
Rivastigmine (Rx) 1059
Rizatriptan (Rx) 1060
Roflumilast 1061
Romiplostim (Rx) 1063
Ropinirole (Rx) 1064
Rosiglitazone (Rx) 1066
Rosuvastatin (Rx) 1067
Rufinamide (Rx) 1068
S e
S 1070
Salicylic acid topical 1070
Salmeterol (Rx) 1070
Sargramostim (GM-CSF) (Rx) 1071
Saxagliptin (Rx) 1073
Scopolamine (Rx) 1074
Scopolamine ophthalmic 1075
Selegiline (Rx) 1075
Selenium topical 1077
Sertraline (Rx) 1077
Sildenafil (Rx) 1079
Silodosin (Rx) 1081
Silver nitrate 1% ophthalmic 1082
Silver nitrate 1% sulfacetamide sodium ophthalmic 1082
Silver sulfadiazine topical 1082
Simethicone (OTC, Rx) 1082
Simvastatin (Rx) 1083
Sirolimus (Rx) 1084
Sitagliptin (Rx) 1086
Sodium bicarbonate (Rx, OTC) 1087
Sodium polystyrene sulfonate (Rx) 1089
Solifenacin (Rx) 1091
Somatropin (Rx) 1092
Sotalol (Rx) 1098
Spironolactone (Rx) 1100
Stavudine d4t (Rx) 1102
Succinylcholine (Rx) 1103
Sucralfate (Rx) 1105
Sulfamethoxazole-trimethoprim (Rx) 1106
Sulfasalazine (Rx) 1108
Sumatriptan (Rx) 1110
Sunitinib (Rx) 1112
Suprofen ophthalmic 1113
T e
T 1114
Tacrolimus (Rx) (PO, IV) 1114
Tacrolimus (topical) (Rx) 1114
Tadalafil (Rx) 1117
Tamoxifen (Rx) 1118
Tamsulosin (Rx) 1120
Tapentadol (Rx) 1121
Controlled substance schedule II 1121
Action: 1121
Uses: 1121
Contraindications: 1121
Dosage and routes 1121
Side effects 1122
Pharmacokinetics 1122
Interactions 1122
Nursing considerations 1122
Tbo-filgrastim 1123
Telaprevir 1124
Telavancin (Rx) 1126
Telbivudine (Rx) 1128
Telmisartan (Rx) 1129
Temazepam (Rx) 1130
Controlled substance schedule IV (USA), schedule F (Canada) 1130
Action: 1130
Uses: 1130
Contraindications: 1130
Dosage and routes 1130
Side effects 1131
Pharmacokinetics 1131
Interactions 1131
Nursing considerations 1131
Treatment of overdose: 1131
Temozolomide (Rx) 1131
Temsirolimus (Rx) 1133
Tenecteplase (TNK-tPA) (Rx) 1134
Tenofovir (Rx) 1136
Terazosin (Rx) 1137
Terbinafine oral (Rx) 1139
Terbinafine topical 1140
Terbutaline (Rx) 1140
Terconazole vaginal antifungal 1141
Teriflunomide 1141
Teriparatide (Rx) 1142
Tesamorelin 1143
Testosterone cypionate (Rx) 1145
Testosterone enanthate (Rx) 1145
Testosterone gel (Rx) 1145
Testosterone pellets (Rx) 1145
Testosterone transdermal (Rx) 1145
Testosterone buccal (Rx) 1145
Testosterone topical solution 1145
Controlled substance schedule III 1145
Action: 1145
Uses: 1145
Contraindications: 1145
Dosage and routes 1145
Side effects 1146
Pharmacokinetics 1146
Interactions 1146
Nursing considerations 1147
Tetracaine ophthalmic 1147
Tetracaine topical 1147
Tetracycline (Rx) 1147
Tetrahydrozoline nasal agent 1149
Tetrahydrozoline ophthalmic 1149
Theophylline (Rx) 1149
Thiamine (vit B1) (PO-OTC; IV, IM-RX) 1153
Thioridazine (Rx) 1153
Thyroid USP (desiccated) (Rx) 1156
Tiagabine (Rx) 1157
Ticagrelor 1158
Ticarcillin/clavulanate (Rx) 1160
Ticlopidine (Rx) 1162
Tigecycline (Rx) 1163
Timolol (Rx) 1165
Timolol (ophthalmic) 1167
Tinidazole (Rx) 1168
Tinzaparin (Rx) 1170
Tioconazole vaginal antifungal 1171
Tiotropium (Rx) 1171
Tipranavir (Rx) 1172
Tirofiban (Rx) 1174
Tizanidine (Rx) 1176
Tobramycin (Rx) 1177
Tobramycin ophthalmic 1180
Tocilizumab (Rx) 1180
Tofacitinib 1181
Tolcapone (Rx) 1183
Tolnaftate topical 1184
Tolterodine (Rx) 1184
Tolvaptan (Rx) 1185
Topiramate (Rx) 1186
Topotecan (Rx) 1188
Toremifene (Rx) 1190
Torsemide (Rx) 1191
Tramadol (Rx) 1193
Trandolapril (Rx) 1194
Trastuzumab (Rx) 1196
Travoprost ophthalmic 1197
Trazodone (Rx) 1197
Treprostinil (Rx) 1199
Tretinoin (vit A acid, retinoic acid) (Rx) 1201
Tretinoin topical 1202
Triamcinolone (Rx) 1202
Triamcinolone nasal agent 1204
Triamcinolone ophthalmic 1204
Triamcinolone (topical) 1204
Triamcinolone (topical-oral) (Rx, OTC) 1205
Triazolam (Rx) 1205
Controlled substance schedule IV (USA), targeted (CDSA IV) (Canada) 1205
Action: 1205
Uses: 1205
Contraindications: 1205
Dosage and routes 1205
Side effects 1206
Pharmacokinetics 1206
Interactions 1206
Nursing considerations 1206
Treatment of overdose: 1207
Trifluridine ophthalmic 1207
Trimethobenzamide (Rx) 1207
Tropicamide ophthalmic 1208
Trospium (Rx) 1208
U e
U 1209
Undecylenic acid topical 1209
Unoprostone ophthalmic 1209
Ustekinumab (Rx) 1209
V e
V 1210
Valacyclovir (Rx) 1210
Valganciclovir (Rx) 1211
Valproate (Rx) 1213
Valproic acid (Rx) 1213
Divalproex sodium (Rx) 1213
Valsartan (Rx) 1215
Vancomycin (Rx) 1216
Vardenafil (Rx) 1219
Varenicline (Rx) 1220
Vasopressin (Rx) 1221
Vemurafenib 1222
Venlafaxine (Rx) 1224
Verapamil (Rx) 1226
Vidarabine ophthalmic 1229
Vigabatrin (Rx) 1229
Vilazodone (Rx) 1230
Vinblastine (VLB) (Rx) 1231
Vincristine (VCR) (Rx) 1234
Vinorelbine (Rx) 1236
Vismodegib 1238
Vitamin A (Rx, PO-OTC, Rx-IM) 1239
Vitamin E (OTC) 1240
Voriconazole (Rx) 1241
W e
W 1245
Warfarin (Rx) 1245
X e
Z e
Z 1247
Zafirlukast (Rx) 1247
Zaleplon (Rx) 1248
Controlled substance schedule IV 1248
Action: 1248
Uses: 1248
Contraindications: 1248
Dosage and routes 1248
Side effects 1248
Pharmacokinetics 1248
Interactions 1248
Nursing considerations 1248
Zanamivir (Rx) 1249
Zidovudine (Rx) 1250
Zinc (Rx, OTC) 1252
Ziprasidone (Rx) 1253
Ziv-aflibercept 1255
Zoledronic acid (Rx) 1256
Zolmitriptan (Rx) 1258
Zolpidem (Rx) 1259
Controlled substance schedule IV 1259
Action: 1259
Uses: 1259
Contraindications: 1259
Dosage and routes 1259
Side effects 1260
Pharmacokinetics 1260
Interactions 1260
Nursing considerations 1260
Treatment of overdose: 1261
Zonisamide (Rx) 1261
Appendix A e
Appendix A Selected new drugs 1263
Ado-trastuzumab 1263
Afatinib 1265
Canagliflozin 1267
Crofelemer 1268
Dabrafenib 1269
Dapagliflozin 1270
Dolutegravir 1271
Eslicarbazepine 1272
Ibrutinib 1273
Levomilnacipran 1274
Macitentan 1276
Mipomersen 1277
Obinutuzmab 1278
Pomalidomide 1280
Riociguat 1281
Simeprevir 1282
Sofosbuvir 1283
Teduglutide 1284
Trametinib 1285
Vortioxetine 1286
Appendix B e
Appendix B Ophthalmic, otic, nasal, and topical products 1288
Appendix C  Vaccines and toxoids 1299
Recent FDA drug approvals 1306
Index 1307
0–9, and symbols 1307
A 1307
B 1312
C 1315
D 1320
E 1323
F 1325
G 1327
H 1328
I 1332
J 1334
K 1334
L 1335
M 1337
N 1340
O 1343
P 1345
Q 1350
R 1350
S 1352
T 1356
U 1359
V 1360
W 1361
X 1362
Y 1362
Z 1362
End sheets 1365
Formulas 1365
Surface area rule: 1365
Calculating strength of a solution: 1365
Calculating flow rate for IV: 1365
Calculation of medication dosages: 1365
Formula method: 1365
Ratio–proportion method: 1365
Dimensional analysis method: 1365
Temperature conversion: 1365
Nomogram for calculation of body surface area 1366
Antitoxins and antivenins bfc
Abbreviations bfc