Additional Information
Book Details
Abstract
- Take advantage of comprehensive yet concise coverage of nearly every type of cytology , including gynecologic, non-gynecologic, and FNA.
- Understand the clinical implications of your diagnoses and better equip yourself to make effective interpretations with clinical correlations emphasized throughout.
- Make the most informed reporting decisions through an in-depth analysis of common diagnostic pitfalls.
- Quickly find the answers you need with succinct, bulleted text, valuable clinical pearls, and useful summaries of key points.
- Gain real-life perspective on a complete range of cytologic findings with over 700 crystal-clear, full-color illustrations.
- Access expert knowledge and key insights into HPV testing; new billing and coding guidelines; patient management discussions; and much more, thanks to comprehensive updates throughout.
- See how to perform fine needle biopsy aspiration with a new 17-minute video available at Expert Consult. Narrated by pathologist Dr. Amy Ly, the video includes a patient interview, precautions, and demonstrations of techniques.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
IFC | IFC | ||
Cytology: Diagnostic Principles and Clinical Correlates | iii | ||
Copyright | iv | ||
Dedication | v | ||
CONTRIBUTORS | vii | ||
PREFACE | ix | ||
ACKNOWLEDGMENTS | xi | ||
CONTENTS | xiii | ||
CHAPTER 1 - CERVICAL AND VAGINAL CYTOLOGY | 1 | ||
History of the Papanicolaou Test and Its Current Practice | 2 | ||
Sampling and Preparation Methods | 3 | ||
Automated Screening | 5 | ||
Accuracy and Reproducibility | 7 | ||
The Bethesda System | 8 | ||
The Normal Pap | 10 | ||
Organisms and Infections | 18 | ||
Benign and Reactive Changes | 23 | ||
Vaginal Specimens in “DES Daughters” | 28 | ||
Squamous Abnormalities | 28 | ||
Glandular Abnormalities | 40 | ||
Other Malignant Neoplasms | 49 | ||
Endometrial Cells in Women Older than 40 Years of Age | 50 | ||
REFERENCES | 52 | ||
CHAPTER 2 - RESPIRATORY TRACT AND MEDIASTINUM | 59 | ||
Molecular Testing of Lung Cancers | 64 | ||
Benign Cellular Changes | 66 | ||
Infections | 69 | ||
Benign Neoplasms of the Lung | 78 | ||
Lung Cancer | 79 | ||
Uncommon Pulmonary Tumors | 93 | ||
Metastatic Cancers to the Lung | 95 | ||
Tumors of the Mediastinum | 95 | ||
REFERENCES | 98 | ||
CHAPTER 3 - URINE AND BLADDER WASHINGS | 105 | ||
Specimen Collection | 106 | ||
Processing | 107 | ||
Reporting Terminology and Adequacy Criteria | 107 | ||
Accuracy | 107 | ||
Normal Elements | 108 | ||
Benign Lesions | 110 | ||
Urothelial Neoplasms | 113 | ||
Other Malignant Lesions | 118 | ||
Diagnosing Difficult or Borderline Specimens: Common Patterns | 120 | ||
Ancillary Techniques | 121 | ||
Summary | 123 | ||
REFERENCES | 123 | ||
CHAPTER 4 - PLEURAL, PERICARDIAL, AND PERITONEAL FLUIDS | 127 | ||
Specimen Collection, Preparation, and Reporting Terminology | 127 | ||
Accuracy | 128 | ||
Benign Elements | 128 | ||
Non-Neoplastic Conditions | 130 | ||
Eosinophilic Effusions | 130 | ||
Malignant Effusions | 133 | ||
REFERENCES | 151 | ||
CHAPTER 5 - PERITONEAL WASHINGS | 155 | ||
Accuracy | 156 | ||
The Normal Peritoneal Washing | 156 | ||
Benign Conditions | 157 | ||
Malignant Tumors | 160 | ||
REFERENCES | 168 | ||
CHAPTER 6 - CEREBROSPINAL FLUID | 171 | ||
Anatomy and Physiology | 171 | ||
Obtaining and Preparing the Specimen | 171 | ||
Reporting Terminology | 172 | ||
Accuracy | 172 | ||
Normal Elements | 173 | ||
Abnormal Inflammatory Cells | 174 | ||
Non-Neoplastic Disorders | 177 | ||
Neoplasms | 180 | ||
REFERENCES | 193 | ||
CHAPTER 7 - GASTROINTESTINAL TRACT | 197 | ||
Clinical Indications | 197 | ||
Sample Collection and Processing | 198 | ||
Accuracy | 199 | ||
Review of Morphologic Findings | 199 | ||
Esophagus | 200 | ||
Stomach | 206 | ||
Duodenum | 212 | ||
Colon | 215 | ||
The Anal Pap Test | 215 | ||
REFERENCES | 216 | ||
CHAPTER 8 - FINE-NEEDLE ASPIRATION BIOPSY TECHNIQUE AND SPECIMEN HANDLING | 221 | ||
Introduction | 221 | ||
Materials and Supplies | 221 | ||
Preparing the Sample | 224 | ||
Variations on Biopsy Technique | 230 | ||
Complications | 231 | ||
Management of Adverse and Unexpected Events | 231 | ||
ACKNOWLEDGEMENTS | 232 | ||
REFERENCES | 232 | ||
ADDITIONAL RESOURCE | 232 | ||
CHAPTER 9 - BREAST | 233 | ||
Specimen Types | 233 | ||
Reporting Terminology | 235 | ||
Evaluation of the Specimen | 236 | ||
The Normal Breast | 237 | ||
Benign Conditions | 237 | ||
Papillary Neoplasms | 245 | ||
Phyllodes Tumor | 246 | ||
Breast Cancer | 248 | ||
Uncommon Breast Tumors | 255 | ||
Metastatic Tumors | 258 | ||
REFERENCES | 259 | ||
CHAPTER 10 - THYROID | 267 | ||
Aspiration Technique and Slide Preparation | 268 | ||
Terminology for Reporting Results | 269 | ||
Accuracy | 270 | ||
Ancillary Molecular Testing | 270 | ||
Evaluation of the Specimen | 270 | ||
Benign Conditions | 271 | ||
Suspicious for a Follicular Neoplasm | 279 | ||
Suspicious for a Follicular Neoplasm, Hürthle Cell Type | 280 | ||
Malignant Conditions | 282 | ||
Atypia of Undetermined Significance (or Follicular Lesion of Undetermined Significance) | 292 | ||
Parathyroid Tumors | 293 | ||
REFERENCES | 293 | ||
CHAPTER 11 - SALIVARY GLAND | 299 | ||
Rationale, Indications, and Technical Considerations | 299 | ||
Diagnostic Overview | 300 | ||
The Normal Aspirate | 301 | ||
Non-Neoplastic Conditions | 302 | ||
Benign Neoplasms | 308 | ||
Carcinomas of Salivary Gland Origin | 316 | ||
Rare Malignant Neoplasms | 322 | ||
Other Malignancies | 326 | ||
Miscellaneous | 327 | ||
REFERENCES | 327 | ||
CHAPTER 12 - LYMPH NODES | 333 | ||
Technical Aspects | 334 | ||
Reporting Terminology and Accuracy | 334 | ||
Ancillary Studies | 335 | ||
Non-Neoplastic Lesions | 337 | ||
Neoplasms | 347 | ||
REFERENCES | 370 | ||
CHAPTER 13 - LIVER | 375 | ||
The Normal Liver | 375 | ||
Infections | 377 | ||
Benign Lesions | 378 | ||
REFERENCES | 394 | ||
CHAPTER 14 - PANCREAS AND BILIARY TREE | 399 | ||
Indications | 399 | ||
Sampling Techniques | 399 | ||
Complications | 400 | ||
Rapid On-Site Evaluation | 400 | ||
Sample Preparation and Cyst Fluid Analysis | 400 | ||
Accuracy and Limitations | 400 | ||
Reporting Terminology | 401 | ||
Normal Pancreas and Bile Duct | 401 | ||
Pancreatitis and Reactive Changes | 403 | ||
Pancreatic Intraepithelial Neoplasia | 404 | ||
Ductal Adenocarcinoma | 404 | ||
Variants of Ductal Adenocarcinoma | 405 | ||
Pancreatic Neuroendocrine Tumor | 407 | ||
Acinar Cell Carcinoma | 410 | ||
Solid-Pseudopapillary Neoplasm | 411 | ||
Pancreatoblastoma | 413 | ||
Pancreatic Cysts | 413 | ||
Secondary Pancreatic Neoplasms and Ectopic Splenic Tissue | 417 | ||
REFERENCES | 418 | ||
CHAPTER 15 - KIDNEY AND ADRENAL GLAND | 423 | ||
The Kidney | 423 | ||
The Adrenal Gland | 442 | ||
REFERENCES | 446 | ||
CHAPTER 16 - OVARY | 453 | ||
Obtaining the Specimen | 454 | ||
Accuracy | 454 | ||
Benign Tumorlike Lesions of the Ovary | 455 | ||
Germ Cell Tumors | 463 | ||
Sex Cord–Stromal Tumors | 465 | ||
Uncommon Primary Ovarian Tumors | 469 | ||
Metastatic Tumors | 469 | ||
REFERENCES | 469 | ||
CHAPTER 17 - SOFT TISSUE | 471 | ||
Ancillary Studies | 473 | ||
Reporting Terminology | 473 | ||
Myxoid Neoplasms | 480 | ||
Spindle Cell Neoplasms | 488 | ||
So-Called Fibrohistiocytic Neoplasms | 499 | ||
Round Cell Neoplasms | 501 | ||
Epithelioid Neoplasms | 505 | ||
Pleomorphic Neoplasms | 510 | ||
Dedifferentiated Sarcomas | 512 | ||
Non-Neoplastic Soft Tissue Lesions | 512 | ||
REFERENCES | 514 | ||
CHAPTER 18 - LABORATORY MANAGEMENT | 519 | ||
Agencies and Organizations | 519 | ||
Regulations | 520 | ||
Laboratory Personnel | 521 | ||
Policy and Procedure Manuals | 523 | ||
Workflow | 523 | ||
Billing | 524 | ||
Quality Control and Quality Assurance | 534 | ||
Competency Assessment | 536 | ||
Proficiency Testing | 537 | ||
Performance Evaluation | 538 | ||
Safety | 541 | ||
REFERENCES | 545 | ||
INDEX | 547 | ||
IBC | IBC |