BOOK
Hematopoietic Neoplasms: Controversies in Diagnosis and Classification, An Issue of Surgical Pathology Clinics, E-Book
(2013)
Additional Information
Book Details
Abstract
Topics in Hematopoietic Neoplasms: Controversies in Diagnosis and Classification include: ABC vs GC subtyping of diffuse large B cell lymphoma-Does it matter?; Clonal link between malignant lymphoma and histiocytic tumors; Diagnostic criteria for grey zone lymphoma: Are there any?; Diagnostic criteria for primary cutaneous B cell lymphoma; Distinguishing reactive and leukemic large granular lymphocyte proliferations; Differential diagnosis of erythroleukemia; Early pre-T ALL versus MPAL: Diagnostic criteria; Myeloid neoplasms with inv(3) or t(3;3); Update on classification and prognosis in myelodysplastic syndrome; Approach to atypical immunophenotypes in Hodgkin lymphoma; Blastic plasmacytoid dendritic cell tumor: How do you distinguish it from acute myeloid leukemia?; The differential diagnosis of eosinophilia in neoplastic hematopathology; Transformation in myeloproliferative neoplasms; and Challenges in consolidated reporting of hematopoietic neoplasms. This publication is an extremely useful and practical source for pathologists working with this spectrum of disorders. As with all publications in this series, Differential Diagnosis is the main focus of discussion. Staging, Diagnosis, Prognosis, and summaries of Pitfalls in working with these pathologies are presented along with ample figures.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front Cover | Cover | ||
| Hematopoietic Neoplasms: Controversies in Diagnosis and Classification \r | i | ||
| Copyright\r | ii | ||
| Contributors | iii | ||
| Contents | v | ||
| Surgical Pathology Clinics\r | viii | ||
| Preface\x0B | ix | ||
| Clonal Relationships Between Malignant Lymphomas and Histiocytic/Dendritic Cell Tumors | 619 | ||
| Abstract | 619 | ||
| Introduction | 619 | ||
| Microscopic features | 620 | ||
| Differential diagnosis | 620 | ||
| Diagnosis | 622 | ||
| Prognosis | 627 | ||
| References | 627 | ||
| Distinguishing T-cell Large Granular Lymphocytic Leukemia from Reactive Conditions | 631 | ||
| Abstract | 631 | ||
| Introduction | 631 | ||
| Gross and microscopic features | 632 | ||
| Differential diagnosis | 633 | ||
| Diagnosis | 636 | ||
| Prognosis | 638 | ||
| References | 638 | ||
| Erythroleukemia and Its Differential Diagnosis | 641 | ||
| Abstract | 641 | ||
| Acute erythroid leukemia, erythroid/myeloid subtype (acute erythroleukemia) | 641 | ||
| Definition | 641 | ||
| Clinical Features | 642 | ||
| Diagnosis: Blood and Bone Marrow Morphology | 642 | ||
| Diagnosis: Cytochemistry and Immunophenotype | 645 | ||
| Diagnosis: Genetics | 645 | ||
| Differential diagnosis | 646 | ||
| Myelodysplastic Syndrome with Erythroid Predominance | 646 | ||
| Reactive Conditions | 649 | ||
| Myeloproliferative Neoplasms and Myelodysplastic/Myeloproliferative Neoplasms | 649 | ||
| Other Types of Acute Myeloid Leukemia | 650 | ||
| Prognosis and Predictive Factors | 650 | ||
| Pure erythroid leukemia | 650 | ||
| Definition | 650 | ||
| Clinical Features | 651 | ||
| Diagnosis: Peripheral Blood and Bone Marrow Morphology | 651 | ||
| Diagnosis: Cytochemistry and Immunophenotype | 651 | ||
| Diagnosis: Genetics | 654 | ||
| Differential Diagnosis | 654 | ||
| Myelodysplastic Syndromes | 654 | ||
| Reactive Erythroid Hyperplasia | 654 | ||
| Other Types of Acute Leukemia | 654 | ||
| Other Neoplasms Involving the Bone Marrow | 657 | ||
| Prognosis | 657 | ||
| References | 657 | ||
| Early T-cell Precursor Acute Lymphoblastic Leukemia/Lymphoma | 661 | ||
| Abstract | 661 | ||
| Overview | 661 | ||
| Stages of T-cell development and the early T-cell precursor | 661 | ||
| Epidemiology and presenting clinical features | 663 | ||
| Flow cytometry | 663 | ||
| Molecular and genetic findings | 664 | ||
| Gene Expression | 664 | ||
| Structural Rearrangements | 665 | ||
| Somatic Mutations | 666 | ||
| Micro RNA Profiling | 666 | ||
| T-cell Receptor Gene Rearrangements | 666 | ||
| Differential diagnosis | 666 | ||
| Prognosis and treatment | 669 | ||
| References | 675 | ||
| Myeloid Neoplasms with inv(3)(q21q26.2) or t(3;3)(q21;q26.2) | 677 | ||
| Abstract | 677 | ||
| Overview | 677 | ||
| Clinical features | 679 | ||
| Diagnosis: microscopic features | 679 | ||
| Diagnosis: ancillary studies | 679 | ||
| Differential diagnosis | 683 | ||
| Prognosis | 689 | ||
| References | 690 | ||
| Update on Myelodysplastic Syndromes Classification and Prognosis | 693 | ||
| Abstract | 693 | ||
| Overview | 693 | ||
| Gross features | 694 | ||
| Microscopic features of MDS | 694 | ||
| Differential diagnosis of MDS | 708 | ||
| Diagnosis of MDS | 719 | ||
| Prognosis of MDS | 719 | ||
| References | 725 | ||
| Atypical Phenotypes in Classical Hodgkin Lymphoma | 729 | ||
| Abstract | 729 | ||
| Overview | 729 | ||
| References | 742 | ||
| Blastic Plasmacytoid Dendritic Cell Neoplasm | 743 | ||
| Abstract | 743 | ||
| Overview | 743 | ||
| Clinical features | 744 | ||
| Microscopic features | 745 | ||
| Diagnosis | 752 | ||
| Differential diagnosis | 758 | ||
| Prognosis | 761 | ||
| References | 763 | ||
| The Differential Diagnosis of Eosinophilia in Neoplastic Hematopathology | 767 | ||
| Abstract | 767 | ||
| Overview | 767 | ||
| Myeloid and lymphoid neoplasms associated with PDGFRA rearrangements | 770 | ||
| Clinical Features | 770 | ||
| Microscopic Features | 772 | ||
| Ancillary Studies | 772 | ||
| Differential Diagnosis | 772 | ||
| Prognosis | 775 | ||
| Myeloid and lymphoid neoplasms associated with PDGFRB rearrangements | 775 | ||
| Clinical Features | 775 | ||
| Microscopic Features | 775 | ||
| Ancillary Studies | 777 | ||
| Differential Diagnosis | 777 | ||
| Prognosis | 778 | ||
| Myeloid and lymphoid neoplasms with FGFR1 abnormalities | 778 | ||
| Clinical Features | 778 | ||
| Microscopic Features and Ancillary Studies | 779 | ||
| Differential Diagnosis | 780 | ||
| Prognosis | 781 | ||
| CEL NOS | 781 | ||
| Clinical Features | 781 | ||
| Microscopic Features | 781 | ||
| Ancillary Studies | 784 | ||
| Differential Diagnosis | 784 | ||
| Prognosis | 784 | ||
| HES | 784 | ||
| Clinical Features | 784 | ||
| Microscopic Features | 785 | ||
| Ancillary Studies | 786 | ||
| Differential Diagnosis | 786 | ||
| Prognosis | 786 | ||
| SM | 787 | ||
| Clinical Features | 787 | ||
| Microscopic Features | 787 | ||
| Ancillary Studies | 789 | ||
| Differential Diagnosis | 790 | ||
| Prognosis | 790 | ||
| References | 790 | ||
| Challenges in Consolidated Reporting of Hematopoietic Neoplasms | 795 | ||
| Abstract | 795 | ||
| Overview | 795 | ||
| Genetic Features of Myeloid Neoplasms and Acute Leukemias | 796 | ||
| Genetic Features of Mature Lymphoid and Other Hematopoietic Neoplasms | 802 | ||
| Unique challenges to comprehensive reporting in pathology | 802 | ||
| How can pathologists incorporate relevant data into a complete synthesized report? | 804 | ||
| References | 805 | ||
| Index | 807 |