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Abstract
The resource of choice for pediatric residencies, clerkships, and exams, Nelson Essentials of Pediatrics continues to provide a focused overview of the core knowledge in pediatrics. Succinct, targeted coverage of normal childhood growth and development, as well as the diagnosis, management, and prevention of common pediatric diseases and disorders, make this an ideal medical reference book for students, pediatric residents, nurse practitioners, and physician assistants.
- Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
- Get an effective overview of pediatrics with help from concise text, a full-color design, high-yield tables, and numerous images.
- Take advantage of a wealth of images that capture the clinical manifestations and findings associated with Kawasaki disease, lupus, lymphoma, stroke, and many other disorders seen in children.
- Efficiently review essential, concise pediatric content with this popular extension of the Nelson Textbook of Pediatrics (ISBN: 978-1-4377-0755-7).
- Focus on the core knowledge needed for your pediatric clerkship or rotation with coverage that follows the COMSEP curriculum guidelines.
- Easily visualize complex aspects with a full-color layout and images, as well as numerous tables throughout the text.
Table of Contents
Section Title | Page | Action | Price |
---|---|---|---|
Front Cover | Cover | ||
IFC | IFC | ||
Nelson Essentials of Pediatrics | v | ||
Copyright | vi | ||
Dedication | vii | ||
Contributors | ix | ||
Preface | xiii | ||
Acknowledgments | xv | ||
Contents | xvii | ||
Section 1 - The Profession of\rPediatrics | 1 | ||
Chapter 1 - POPULATION AND CULTURE: THE CARE OF CHILDREN IN SOCIETY | 1 | ||
CURRENT CHALLENGES | 1 | ||
LANDSCAPE OF HEALTH CARE FOR CHILDREN IN THE UNITED STATES | 1 | ||
OTHER HEALTH ISSUES THAT AFFECT CHILDREN IN THE UNITED STATES | 2 | ||
HEALTH DISPARITIES IN HEALTH CARE FOR CHILDREN | 3 | ||
CHANGING MORBIDITY: THE SOCIAL/EMOTIONAL ASPECTS OF PEDIATRIC PRACTICE | 3 | ||
CULTURE | 3 | ||
Chapter 2 - PROFESSIONALISM | 4 | ||
CONCEPT OF PROFESSIONALISM | 4 | ||
PROFESSIONALISM FOR PEDIATRICIANS | 4 | ||
Chapter 3 - ETHICS AND LEGAL ISSUES | 5 | ||
ETHICS IN HEALTH CARE | 5 | ||
ETHICAL PRINCIPLES RELATED TO INFANTS, CHILDREN, AND ADOLESCENTS | 5 | ||
LEGAL ISSUES | 5 | ||
ETHICAL ISSUES IN PRACTICE | 6 | ||
Chapter 4 - PALLIATIVE CARE AND END-OF-LIFE ISSUES | 7 | ||
PALLIATIVE AND END-OF-LIFE CARE | 7 | ||
BEREAVEMENT | 8 | ||
COGNITIVE ISSUES IN CHILDREN AND ADOLESCENTS: UNDERSTANDING DEATH AND DYING | 8 | ||
CULTURAL, RELIGIOUS, AND SPIRITUAL CONCERNS ABOUT PALLIATIVE CARE AND END-OF-LIFE DECISIONS | 9 | ||
ETHICAL ISSUES IN END-OF-LIFE DECISION MAKING | 9 | ||
Suggested Reading | 9 | ||
Section 2 - Growth and Development | 10 | ||
THE HEALTH MAINTENANCE VISIT | 10 | ||
Chapter 5 - NORMAL GROWTH | 10 | ||
Chapter 6 - DISORDERS OF GROWTH | 12 | ||
Chapter 7 - NORMAL DEVELOPMENT | 13 | ||
PHYSICAL DEVELOPMENT | 13 | ||
NEWBORN PERIOD | 13 | ||
LATER INFANCY | 13 | ||
SCHOOL AGE/PREADOLESCENT | 13 | ||
ADOLESCENCE | 13 | ||
DEVELOPMENTAL MILESTONES | 13 | ||
PSYCHOSOCIAL ASSESSMENT | 14 | ||
MODIFYING PSYCHOSOCIAL BEHAVIORS | 15 | ||
TEMPERAMENT | 15 | ||
Chapter 8 - DISORDERS OF DEVELOPMENT | 15 | ||
DEVELOPMENTAL SURVEILLANCE AND SCREENING | 15 | ||
OTHER ISSUES IN ASSESSING DEVELOPMENT AND BEHAVIOR | 19 | ||
Chapter 9 - EVALUATION OF THE WELL CHILD | 20 | ||
EVALUATING DEVELOPMENTAL AND BEHAVIORAL ISSUES | 20 | ||
SCREENING TESTS | 21 | ||
IMMUNIZATIONS | 22 | ||
DENTAL CARE | 23 | ||
NUTRITIONAL ASSESSMENT | 23 | ||
ANTICIPATORY GUIDANCE | 23 | ||
Chapter 10 - EVALUATION OF THE CHILD WITH SPECIAL NEEDS | 26 | ||
MULTIFACETED TEAM ASSESSMENT OF COMPLEX PROBLEMS | 26 | ||
MANAGEMENT OF DEVELOPMENTAL PROBLEMS | 29 | ||
SELECTED CLINICAL PROBLEMS: THE SPECIAL NEEDS CHILD | 31 | ||
Suggested Reading | 36 | ||
Section 3 - Behavioral Disorders | 37 | ||
Chapter 11 - CRYING AND COLIC | 37 | ||
NORMAL DEVELOPMENT | 37 | ||
COLIC | 37 | ||
Chapter 12 - TEMPER TANTRUMS | 39 | ||
ETIOLOGY | 39 | ||
EPIDEMIOLOGY | 39 | ||
CLINICAL MANIFESTATIONS | 39 | ||
DIFFERENTIAL DIAGNOSIS | 40 | ||
TREATMENT | 40 | ||
PREVENTION | 40 | ||
Chapter 13 - ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | 41 | ||
ETIOLOGY | 41 | ||
EPIDEMIOLOGY | 41 | ||
CLINICAL MANIFESTATIONS | 41 | ||
DIFFERENTIAL DIAGNOSIS | 41 | ||
TREATMENT | 41 | ||
COMPLICATIONS | 42 | ||
PREVENTION | 42 | ||
Chapter 14 - CONTROL OF ELIMINATION | 43 | ||
NORMAL DEVELOPMENT OF ELIMINATION | 43 | ||
ENURESIS | 43 | ||
FUNCTIONAL CONSTIPATION AND SOILING | 44 | ||
Chapter 15 - NORMAL SLEEP AND PEDIATRIC SLEEP DISORDERS | 47 | ||
SLEEP DISORDERS | 48 | ||
Suggested Reading | 50 | ||
Section 4 - Psychiatric Disorders | 51 | ||
Chapter 16 - SOMATOFORM DISORDERS, FACTITIOUS DISORDERS, AND MALINGERING | 51 | ||
FACTITIOUS DISORDERS AND MALINGERING | 54 | ||
Chapter 17 - ANXIETY AND PHOBIAS | 55 | ||
ANXIETY DISORDERS | 55 | ||
Chapter 18 - DEPRESSION AND BIPOLAR DISORDERS | 59 | ||
DEPRESSION | 59 | ||
BIPOLAR DISORDERS | 60 | ||
Chapter 19 - OBSESSIVE-COMPULSIVE DISORDER | 62 | ||
Chapter 20 - PERVASIVE DEVELOPMENTAL DISORDERS AND PSYCHOSES | 63 | ||
AUTISM | 63 | ||
SCHIZOPHRENIA | 64 | ||
Suggested Reading | 66 | ||
Section 5 - Psychosocial Issues | 67 | ||
Chapter 21 - FAILURE TO THRIVE | 67 | ||
ETIOLOGY | 67 | ||
DIAGNOSIS AND CLINICAL MANIFESTATIONS | 67 | ||
TREATMENT | 69 | ||
COMPLICATIONS | 69 | ||
Chapter 22 - CHILD ABUSE AND NEGLECT | 70 | ||
PHYSICAL ABUSE | 70 | ||
SEXUAL ABUSE | 73 | ||
MANAGEMENT | 73 | ||
Chapter 23 - HOMOSEXUALITY AND GENDER IDENTITY | 75 | ||
DEVELOPMENT OF SEXUAL IDENTITY | 75 | ||
GENDER IDENTITY DISORDER | 75 | ||
Chapter 24 - FAMILY STRUCTURE AND FUNCTION | 76 | ||
FAMILY FUNCTIONS | 76 | ||
HOMOSEXUALITY | 76 | ||
FAMILY STRUCTURE | 77 | ||
FAMILY DYSFUNCTION | 79 | ||
Chapter 25 - VIOLENCE | 79 | ||
INTIMATE PARTNER VIOLENCE AND CHILDREN | 79 | ||
YOUTH VIOLENCE | 80 | ||
Chapter 26 - DIVORCE, SEPARATION, AND BEREAVEMENT | 82 | ||
DIVORCE | 82 | ||
DATING VIOLENCE AND DATE RAPE | 82 | ||
SEPARATIONS FROM PARENTS | 84 | ||
DEATH OF A PARENT OR FAMILY MEMBER AND BEREAVEMENT | 84 | ||
Suggested Readings | 85 | ||
Section 6 - Pediatric Nutrition and\rNutritional Disorders | 86 | ||
Chapter 27 - DIET OF THE NORMAL INFANT | 86 | ||
BREASTFEEDING | 86 | ||
FORMULA FEEDING | 88 | ||
COMPLEMENTARY FOODS | 89 | ||
Chapter 28 - DIET OF THE NORMAL CHILD AND ADOLESCENT | 89 | ||
NUTRITION ISSUES FOR TODDLERS AND OLDER CHILDREN | 89 | ||
MILK | 89 | ||
JUICES | 89 | ||
GENERAL RECOMMENDATIONS | 89 | ||
Chapter 29 - OBESITY | 90 | ||
EPIDEMIOLOGY | 90 | ||
IRON INTAKE | 90 | ||
NUTRITION ISSUES FOR ADOLESCENTS | 90 | ||
CLINICAL MANIFESTATIONS | 91 | ||
ASSESSMENT | 91 | ||
PREVENTION | 92 | ||
TREATMENT | 92 | ||
Chapter 30 - PEDIATRIC UNDERNUTRITION | 93 | ||
FAILURE TO THRIVE | 94 | ||
MARASMUS | 94 | ||
KWASHIORKOR | 94 | ||
MIXED MARASMUS-KWASHIORKOR | 95 | ||
TREATMENT OF MALNUTRITION | 95 | ||
Chapter 31 - VITAMIN AND MINERAL DEFICIENCIES | 96 | ||
WATER-SOLUBLE VITAMINS | 96 | ||
COMPLICATIONS OF MALNUTRITION | 96 | ||
FAT-SOLUBLE VITAMINS | 101 | ||
MINERALS | 103 | ||
Suggested Readings | 105 | ||
Section 7 -Fluids and Electrolytes | 106 | ||
Chapter 32 - MAINTENANCE FLUID THERAPY | 106 | ||
BODY COMPOSITION | 106 | ||
REGULATION OF INTRAVASCULAR VOLUME AND OSMOLALITY | 106 | ||
MAINTENANCE FLUIDS | 107 | ||
Chapter 33 - DEHYDRATION AND REPLACEMENT THERAPY | 107 | ||
REPLACEMENT THERAPY | 107 | ||
DEHYDRATION | 108 | ||
Chapter 34 - PARENTERAL NUTRITION | 111 | ||
INDICATIONS | 111 | ||
Chapter 35 - SODIUM DISORDERS | 112 | ||
ACCESS FOR PARENTERAL NUTRITION | 112 | ||
COMPOSITION OF PARENTERAL NUTRITION | 112 | ||
COMPLICATIONS | 112 | ||
HYPONATREMIA | 113 | ||
HYPERNATREMIA | 114 | ||
Chapter 36 - POTASSIUM DISORDERS | 116 | ||
HYPOKALEMIA | 116 | ||
HYPERKALEMIA | 117 | ||
Chapter 37 - ACID-BASE DISORDERS | 119 | ||
CLINICAL ASSESSMENT OF ACID-BASE DISORDERS | 119 | ||
METABOLIC ACIDOSIS | 120 | ||
METABOLIC ALKALOSIS | 121 | ||
RESPIRATORY ACID-BASE DISTURBANCES | 122 | ||
Suggested Reading | 123 | ||
Section 8 - The Acutely Ill or\rInjured Child | 124 | ||
Chapter 38 - ASSESSMENT AND RESUSCITATION | 124 | ||
INITIAL ASSESSMENT | 124 | ||
HISTORY | 124 | ||
PHYSICAL EXAMINATION | 124 | ||
COMMON MANIFESTATIONS | 124 | ||
INITIAL DIAGNOSTIC EVALUATION | 124 | ||
RESUSCITATION | 125 | ||
CARDIOPULMONARY ARREST | 126 | ||
Chapter 39 - RESPIRATORY FAILURE | 128 | ||
ETIOLOGY | 128 | ||
EPIDEMIOLOGY | 128 | ||
CLINICAL MANIFESTATIONS | 128 | ||
LABORATORY AND IMAGING STUDIES | 128 | ||
DIFFERENTIAL DIAGNOSIS | 128 | ||
TREATMENT | 129 | ||
COMPLICATIONS | 129 | ||
PROGNOSIS | 129 | ||
PREVENTION | 129 | ||
Chapter 40 - SHOCK | 129 | ||
ETIOLOGY AND EPIDEMIOLOGY | 129 | ||
HYPOVOLEMIC SHOCK | 129 | ||
DISTRIBUTIVE SHOCK | 130 | ||
CARDIOGENIC SHOCK | 130 | ||
OBSTRUCTIVE SHOCK | 130 | ||
DISSOCIATIVE SHOCK | 130 | ||
CLINICAL MANIFESTATIONS | 130 | ||
LABORATORY AND IMAGING STUDIES | 131 | ||
DIFFERENTIAL DIAGNOSIS | 131 | ||
TREATMENT | 131 | ||
COMPLICATIONS | 132 | ||
PROGNOSIS | 132 | ||
Chapter 41 - INJURY PREVENTION | 133 | ||
EPIDEMIOLOGY AND ETIOLOGY | 133 | ||
EDUCATION FOR PREVENTING INJURIES | 133 | ||
PREVENTION | 133 | ||
Chapter 42 - MAJOR TRAUMA | 133 | ||
ASSESSMENT AND RESUSCITATION | 133 | ||
ETIOLOGY AND EPIDEMIOLOGY | 134 | ||
LABORATORY AND IMAGING STUDIES | 134 | ||
CLINICAL MANIFESTATIONS AND TREATMENT | 134 | ||
COMPLICATIONS | 135 | ||
Chapter 43 - DROWNING | 136 | ||
ETIOLOGY | 136 | ||
EPIDEMIOLOGY | 136 | ||
CLINICAL MANIFESTATIONS | 136 | ||
LABORATORY AND IMAGING STUDIES | 136 | ||
TREATMENT | 136 | ||
Section 9 - Human Genetics\rand Dysmorphology | 146 | ||
Chapter 47 - PATTERNS OF INHERITANCE | 146 | ||
TYPES OF GENETIC DISORDERS | 146 | ||
INTRODUCTION TO GENETICS AND GENOMICS | 146 | ||
OTHER TYPES OF GENETIC DISORDERS | 151 | ||
TERATOGENIC AGENTS | 153 | ||
Chapter 48 - GENETIC ASSESSMENT | 154 | ||
PRECONCEPTION AND PRENATAL COUNSELING | 154 | ||
GENERAL APPROACH TO PATIENTS | 155 | ||
Chapter 49 - CHROMOSOMAL DISORDERS | 156 | ||
ABNORMALITIES IN NUMBER (ANEUPLOIDY) | 157 | ||
SYNDROMES INVOLVING CHROMOSOMAL DELETIONS | 159 | ||
SYNDROMES INVOLVING CHROMOSOME DUPLICATION | 160 | ||
Chapter 50 - THE APPROACH TO THE DYSMORPHIC CHILD | 160 | ||
DEFINITIONS | 160 | ||
HISTORY AND PHYSICAL EXAMINATION | 161 | ||
LABORATORY EVALUATION | 163 | ||
DIAGNOSIS | 163 | ||
Suggested Reading | 163 | ||
Section 10 - Metabolic Disorders | 164 | ||
Chapter 51 - METABOLIC ASSESSMENT | 164 | ||
SIGNS AND SYMPTOMS | 164 | ||
TYPES OF CLINICAL PRESENTATION OF INBORN ERRORS | 165 | ||
CLINICAL ASSESSMENT AND LABORATORY TESTING | 169 | ||
GENETIC ASPECTS OF INBORN ERRORS | 169 | ||
IDENTIFICATION OF INBORN ERRORS BY NEONATAL SCREENING | 170 | ||
OVERVIEW OF TREATMENT | 171 | ||
Chapter 52 - CARBOHYDRATE DISORDERS | 172 | ||
GLYCOGEN STORAGE DISEASES | 172 | ||
GALACTOSEMIA | 173 | ||
Chapter 53 - AMINO ACID DISORDERS | 174 | ||
DISORDERS OF AMINO ACID METABOLISM | 174 | ||
PHENYLKETONURIA | 174 | ||
TYROSINEMIAS | 175 | ||
HOMOCYSTINURIA | 175 | ||
MAPLE SYRUP URINE DISEASE | 176 | ||
DISORDERS OF AMMONIA DISPOSAL | 176 | ||
DISORDERS OF AMINO ACID TRANSPORT THAT AFFECT SPECIFIC TRANSPORT MECHANISMS IN THE KIDNEY AND INTESTINE | 177 | ||
Chapter 54 - ORGANIC ACID DISORDERS | 177 | ||
DISORDERS OF ORGANIC ACID METABOLISM | 177 | ||
PROPIONIC ACIDEMIA AND METHYLMALONIC ACIDEMIA | 177 | ||
ISOVALERIC ACIDEMIA | 178 | ||
GLUTARIC ACIDEMIA I | 178 | ||
BIOTINIDASE DEFICIENCY AND HOLOCARBOXYLASE DEFICIENCY | 178 | ||
Chapter 55 - FAT METABOLIC DISORDERS | 179 | ||
DISORDERS OF FATTY ACID OXIDATION | 179 | ||
GLUTARIC ACIDURIA TYPE II | 179 | ||
Chapter 56 - LYSOSOMAL AND PEROXISOMAL DISORDERS | 180 | ||
PEROXISOMAL DISORDERS | 180 | ||
CARNITINE DEFICIENCY | 180 | ||
LYSOSOMAL STORAGE DISORDERS | 183 | ||
DIAGNOSTIC TESTING | 183 | ||
TREATMENT STRATEGIES | 183 | ||
Chapter 57 - MITOCHONDRIAL DISORDERS | 183 | ||
MITOCHONDRIAL FUNCTION | 183 | ||
SIGNS AND SYMPTOMS OF GENETIC DISORDERS OF MITOCHONDRIAL FUNCTION | 184 | ||
BIOCHEMICAL ABNORMALITIES IN MITOCHONDRIAL FUNCTION | 184 | ||
GENETICS OF MITOCHONDRIAL DISORDERS | 185 | ||
TREATMENT OF MITOCHONDRIAL DISORDERS | 185 | ||
Suggested Reading | 185 | ||
Section 11 - Fetal and Neonatal\rMedicine | 186 | ||
Chapter 58 - ASSESSMENT OF THE MOTHER, FETUS, AND NEWBORN | 186 | ||
ASSESSMENT OF THE MOTHER | 186 | ||
FETUS AND NEWBORN | 187 | ||
ASSESSMENT OF THE FETUS | 188 | ||
ASSESSMENT OF THE NEWBORN | 189 | ||
NEUROLOGIC ASSESSMENT | 200 | ||
MISCELLANEOUS DISORDERS | 204 | ||
Chapter 59 - MATERNAL DISEASES AFFECTING THE NEWBORN | 204 | ||
ANTIPHOSPHOLIPID SYNDROME | 205 | ||
IDIOPATHIC THROMBOCYTOPENIA | 205 | ||
SYSTEMIC LUPUS ERYTHEMATOSUS | 205 | ||
NEONATAL HYPERTHYROIDISM | 206 | ||
DIABETES MELLITUS | 206 | ||
OTHER CONDITIONS | 206 | ||
Chapter 60 - DISEASES OF THE FETUS | 208 | ||
INTRAUTERINE GROWTH RESTRICTION AND SMALL FOR GESTATIONAL AGE | 208 | ||
HYDROPS FETALIS | 209 | ||
Chapter 61 - RESPIRATORY DISEASES OF THE NEWBORN | 209 | ||
RESPIRATORY DISTRESS SYNDROME (HYALINE MEMBRANE DISEASE) | 210 | ||
COMPLICATIONS OF RESPIRATORY DISTRESS SYNDROME | 212 | ||
TRANSIENT TACHYPNEA OF THE NEWBORN | 214 | ||
MECONIUM ASPIRATION SYNDROME | 214 | ||
PRIMARY PULMONARY HYPERTENSION OF THE NEWBORN | 215 | ||
APNEA OF PREMATURITY | 215 | ||
Chapter 62 - ANEMIA AND HYPERBILIRUBINEMIA | 216 | ||
ANEMIA | 216 | ||
HYPERBILIRUBINEMIA | 219 | ||
COAGULATION DISORDERS | 222 | ||
Chapter 63 - NECROTIZING ENTEROCOLITIS | 223 | ||
Chapter 64 - HYPOXIC-ISCHEMIC ENCEPHALOPATHY, INTRACRANIAL HEMORRHAGE, AND SEIZURES | 224 | ||
NEONATAL SEIZURES | 224 | ||
INTRACRANIAL HEMORRHAGE | 226 | ||
HYPOXIC-ISCHEMIC ENCEPHALOPATHY | 226 | ||
Chapter 65 - SEPSIS AND MENINGITIS | 227 | ||
Chapter 66 - CONGENITAL INFECTIONS | 229 | ||
TOXOPLASMOSIS | 229 | ||
RUBELLA | 229 | ||
CYTOMEGALOVIRUS | 231 | ||
HERPES SIMPLEX VIRUS | 231 | ||
CONGENITAL SYPHILIS | 232 | ||
HUMAN IMMUNODEFICIENCY VIRUS | 232 | ||
HEPATITIS B | 232 | ||
NEISSERIA GONORRHOEAE | 232 | ||
CHLAMYDIA | 233 | ||
MYCOBACTERIUM TUBERCULOSIS | 233 | ||
Suggested Reading | 233 | ||
Section 12 - Adolescent Medicine | 234 | ||
Chapter 67 - OVERVIEW AND ASSESSMENT OF ADOLESCENTS | 234 | ||
INTERVIEWING ADOLESCENTS | 234 | ||
PHYSICAL GROWTH AND DEVELOPMENT OF ADOLESCENTS | 237 | ||
PSYCHOLOGICAL GROWTH AND DEVELOPMENT OF ADOLESCENTS | 240 | ||
Chapter 68 - WELL-ADOLESCENT CARE | 240 | ||
EARLY ADOLESCENCE (AGES 10 TO 14 YEARS) | 240 | ||
MIDDLE ADOLESCENCE (AGES 15 TO 17 YEARS) | 240 | ||
LATE ADOLESCENCE (AGES 18 TO 21 YEARS) | 240 | ||
PELVIC EXAMINATION | 240 | ||
NORMAL VARIANTS OF PUBERTY | 241 | ||
Chapter 69 - ADOLESCENT GYNECOLOGY | 242 | ||
MENSTRUAL DISORDERS | 242 | ||
PREGNANCY | 244 | ||
CONTRACEPTION | 245 | ||
RAPE | 247 | ||
Chapter 70 - EATING DISORDERS | 248 | ||
ANOREXIA NERVOSA | 248 | ||
BULIMIA NERVOSA | 248 | ||
Chapter 71 - SUBSTANCE ABUSE | 250 | ||
ACUTE OVERDOSE | 250 | ||
ACUTE AND CHRONIC EFFECTS | 251 | ||
TREATMENT | 251 | ||
Suggested Reading | 251 | ||
Section 13 - Immunology | 252 | ||
Chapter 72 - ASSESSMENT | 252 | ||
HISTORY | 253 | ||
PHYSICAL EXAMINATION | 254 | ||
DIFFERENTIAL DIAGNOSIS | 254 | ||
DIAGNOSTIC EVALUATION | 255 | ||
Chapter 73 - LYMPHOCYTE DISORDERS | 256 | ||
ETIOLOGY AND CLINICAL MANIFESTATIONS | 256 | ||
TREATMENT | 262 | ||
PREVENTION AND NEWBORN SCREENING | 263 | ||
Chapter 74 - NEUTROPHIL DISORDERS | 263 | ||
ETIOLOGY AND CLINICAL MANIFESTATIONS | 263 | ||
Chapter 75 - COMPLEMENT SYSTEM | 266 | ||
LABORATORY DIAGNOSIS | 266 | ||
TREATMENT | 266 | ||
PROGNOSIS AND PREVENTION | 266 | ||
ETIOLOGY | 267 | ||
LABORATORY STUDIES | 268 | ||
TREATMENT | 269 | ||
Chapter 76 - HEMATOPOIETIC STEM CELL TRANSPLANTATION | 269 | ||
COMPLICATIONS | 270 | ||
Suggested Reading | 270 | ||
Section 14 - Allergy | 271 | ||
Chapter 77 - ASSESSMENT | 271 | ||
HISTORY | 272 | ||
PHYSICAL EXAMINATION | 272 | ||
COMMON MANIFESTATIONS | 272 | ||
INITIAL DIAGNOSTIC EVALUATION | 272 | ||
DIAGNOSTIC IMAGING | 273 | ||
Chapter 78 - ASTHMA | 273 | ||
ETIOLOGY | 273 | ||
EPIDEMIOLOGY | 273 | ||
CLINICAL MANIFESTATIONS | 273 | ||
LABORATORY AND IMAGING STUDIES | 274 | ||
DIFFERENTIAL DIAGNOSIS | 274 | ||
TREATMENT | 274 | ||
COMPLICATIONS | 278 | ||
PROGNOSIS | 278 | ||
PREVENTION | 279 | ||
Chapter 79 - ALLERGIC RHINITIS | 282 | ||
ETIOLOGY | 282 | ||
EPIDEMIOLOGY | 282 | ||
CLINICAL MANIFESTATIONS | 282 | ||
LABORATORY AND IMAGING STUDIES | 283 | ||
DIFFERENTIAL DIAGNOSIS | 283 | ||
TREATMENT | 284 | ||
COMPLICATIONS | 285 | ||
PROGNOSIS AND PREVENTION | 285 | ||
Chapter 80 - ATOPIC DERMATITIS | 285 | ||
ETIOLOGY | 285 | ||
EPIDEMIOLOGY | 285 | ||
CLINICAL MANIFESTATIONS | 285 | ||
LABORATORY AND IMAGING STUDIES | 286 | ||
DIFFERENTIAL DIAGNOSIS | 286 | ||
TREATMENT | 287 | ||
COMPLICATIONS | 287 | ||
PROGNOSIS | 287 | ||
PREVENTION | 287 | ||
Chapter 81 - URTICARIA, ANGIOEDEMA, AND ANAPHYLAXIS | 288 | ||
ETIOLOGY | 288 | ||
EPIDEMIOLOGY | 289 | ||
CLINICAL MANIFESTATIONS | 289 | ||
LABORATORY AND IMAGING STUDIES | 290 | ||
DIFFERENTIAL DIAGNOSIS | 290 | ||
TREATMENT | 291 | ||
PREVENTION | 291 | ||
Chapter 82 - SERUM SICKNESS | 292 | ||
ETIOLOGY | 292 | ||
EPIDEMIOLOGY | 292 | ||
CLINICAL MANIFESTATIONS | 292 | ||
LABORATORY AND IMAGING STUDIES | 292 | ||
TREATMENT AND PREVENTION | 293 | ||
Chapter 83 - INSECT ALLERGIES | 293 | ||
ETIOLOGY | 293 | ||
EPIDEMIOLOGY | 293 | ||
CLINICAL MANIFESTATIONS | 293 | ||
LABORATORY AND IMAGING STUDIES | 293 | ||
DIFFERENTIAL DIAGNOSIS | 293 | ||
Chapter 84 - ADVERSE REACTIONS TO FOODS | 294 | ||
ETIOLOGY AND EPIDEMIOLOGY | 294 | ||
CLINICAL MANIFESTATIONS | 294 | ||
LABORATORY AND IMAGING STUDIES | 294 | ||
DIAGNOSIS | 294 | ||
TREATMENT | 294 | ||
COMPLICATIONS | 294 | ||
PROGNOSIS | 294 | ||
PREVENTION | 294 | ||
TREATMENT | 296 | ||
COMPLICATIONS | 296 | ||
PROGNOSIS AND PREVENTION | 296 | ||
Chapter 85 - ADVERSE REACTIONS TO DRUGS | 296 | ||
ETIOLOGY | 296 | ||
EPIDEMIOLOGY | 296 | ||
CLINICAL MANIFESTATIONS | 297 | ||
LABORATORY AND IMAGING STUDIES | 297 | ||
DIFFERENTIAL DIAGNOSIS | 297 | ||
TREATMENT | 297 | ||
COMPLICATIONS | 298 | ||
PROGNOSIS | 298 | ||
PREVENTION | 298 | ||
Suggested Reading | 298 | ||
Section 15 - Rheumatic Diseases\rof Childhood | 299 | ||
Chapter 86 - ASSESSMENT | 299 | ||
HISTORY | 299 | ||
PHYSICAL EXAMINATION | 299 | ||
COMMON MANIFESTATIONS | 299 | ||
INITIAL DIAGNOSTIC EVALUATION | 301 | ||
LABORATORY TESTING | 301 | ||
DIAGNOSTIC IMAGING | 301 | ||
Chapter 87 - HENOCH-SCHÖNLEIN PURPURA | 301 | ||
ETIOLOGY | 301 | ||
EPIDEMIOLOGY | 301 | ||
CLINICAL MANIFESTATIONS | 302 | ||
LABORATORY AND IMAGING STUDIES | 302 | ||
DIFFERENTIAL DIAGNOSIS | 302 | ||
TREATMENT | 302 | ||
COMPLICATIONS | 302 | ||
Chapter 88 - KAWASAKI DISEASE | 303 | ||
ETIOLOGY | 303 | ||
EPIDEMIOLOGY | 303 | ||
CLINICAL MANIFESTATIONS | 303 | ||
PROGNOSIS | 303 | ||
LABORATORY AND IMAGING STUDIES | 304 | ||
DIFFERENTIAL DIAGNOSIS | 304 | ||
TREATMENT | 304 | ||
COMPLICATIONS | 305 | ||
PROGNOSIS | 305 | ||
Chapter 89 - JUVENILE IDIOPATHIC ARTHRITIS | 305 | ||
ETIOLOGY | 305 | ||
EPIDEMIOLOGY | 305 | ||
CLINICAL PRESENTATION | 305 | ||
LABORATORY AND IMAGING STUDIES | 307 | ||
DIFFERENTIAL DIAGNOSIS | 307 | ||
TREATMENT | 308 | ||
COMPLICATIONS | 308 | ||
PROGNOSIS | 308 | ||
Chapter 90 - SYSTEMIC LUPUS ERYTHEMATOSUS | 309 | ||
ETIOLOGY | 309 | ||
EPIDEMIOLOGY | 309 | ||
CLINICAL MANIFESTATIONS | 309 | ||
LABORATORY AND IMAGING STUDIES | 309 | ||
DIFFERENTIAL DIAGNOSIS | 311 | ||
TREATMENT | 311 | ||
COMPLICATIONS | 311 | ||
PROGNOSIS | 311 | ||
Chapter 91 - JUVENILE DERMATOMYOSITIS | 311 | ||
ETIOLOGY | 311 | ||
EPIDEMIOLOGY | 311 | ||
CLINICAL MANIFESTATIONS | 311 | ||
Chapter 92 - MUSCULOSKELETAL PAIN SYNDROMES | 312 | ||
GROWING PAINS | 312 | ||
LABORATORY AND IMAGING STUDIES | 312 | ||
DIFFERENTIAL DIAGNOSIS | 312 | ||
TREATMENT | 312 | ||
COMPLICATIONS | 312 | ||
PROGNOSIS | 312 | ||
BENIGN HYPERMOBILITY | 313 | ||
MYOFASCIAL PAIN SYNDROMES AND FIBROMYALGIA | 313 | ||
Suggested Reading | 314 | ||
Section 16 - Infectious Diseases | 315 | ||
Chapter 93 - ASSESSMENT | 315 | ||
INITIAL DIAGNOSTIC EVALUATION | 315 | ||
DIFFERENTIAL DIAGNOSIS | 315 | ||
SCREENING TESTS | 315 | ||
DIAGNOSTIC IMAGING | 317 | ||
Chapter 94 - IMMUNIZATION AND PROPHYLAXIS | 317 | ||
IMMUNIZATION | 317 | ||
PROPHYLAXIS | 318 | ||
Chapter 95 - ANTI-INFECTIVE THERAPY | 323 | ||
Chapter 96 - FEVER WITHOUT A FOCUS | 324 | ||
FEVER IN INFANTS YOUNGER THAN 3 MONTHS OF AGE | 325 | ||
FEVER IN CHILDREN 3 MONTHS TO 3 YEARS OF AGE | 325 | ||
FEVER OF UNKNOWN ORIGIN | 326 | ||
Chapter 97 - INFECTIONS CHARACTERIZED BY FEVER AND RASH | 329 | ||
MEASLES (RUBEOLA) | 329 | ||
RUBELLA (GERMAN OR 3-DAY MEASLES) | 331 | ||
ROSEOLA INFANTUM (EXANTHEM SUBITUM) | 332 | ||
ERYTHEMA INFECTIOSUM (FIFTH DISEASE) | 333 | ||
VARICELLA-ZOSTER VIRUS INFECTION (CHICKENPOX AND ZOSTER) | 333 | ||
Chapter 98 - CUTANEOUS INFECTIONS | 335 | ||
SUPERFICIAL BACTERIAL INFECTIONS | 335 | ||
SUPERFICIAL FUNGAL INFECTIONS | 336 | ||
SUPERFICIAL VIRAL INFECTIONS | 336 | ||
Chapter 99 - LYMPHADENOPATHY | 338 | ||
ETIOLOGY | 338 | ||
EPIDEMIOLOGY | 340 | ||
CLINICAL MANIFESTATIONS | 340 | ||
LABORATORY AND IMAGING STUDIES | 340 | ||
DIFFERENTIAL DIAGNOSIS | 341 | ||
TREATMENT | 341 | ||
COMPLICATIONS AND PROGNOSIS | 341 | ||
Chapter 100 - MENINGITIS | 342 | ||
ETIOLOGY | 342 | ||
EPIDEMIOLOGY | 342 | ||
CLINICAL MANIFESTATIONS | 342 | ||
PREVENTION | 342 | ||
LABORATORY AND IMAGING STUDIES | 343 | ||
DIFFERENTIAL DIAGNOSIS | 343 | ||
TREATMENT | 343 | ||
COMPLICATIONS AND PROGNOSIS | 344 | ||
PREVENTION | 344 | ||
Chapter 101 - ENCEPHALITIS | 344 | ||
ETIOLOGY | 344 | ||
EPIDEMIOLOGY | 345 | ||
CLINICAL MANIFESTATIONS | 345 | ||
DIFFERENTIAL DIAGNOSIS | 345 | ||
LABORATORY AND IMAGING STUDIES | 345 | ||
TREATMENT | 346 | ||
COMPLICATIONS AND PROGNOSIS | 346 | ||
PREVENTION | 346 | ||
Chapter 102 - THE COMMON COLD | 346 | ||
ETIOLOGY | 346 | ||
EPIDEMIOLOGY | 346 | ||
CLINICAL MANIFESTATIONS | 346 | ||
LABORATORY AND IMAGING STUDIES | 347 | ||
DIFFERENTIAL DIAGNOSIS | 347 | ||
TREATMENT | 347 | ||
COMPLICATIONS AND PROGNOSIS | 347 | ||
PREVENTION | 347 | ||
Chapter 103 - PHARYNGITIS | 347 | ||
ETIOLOGY | 347 | ||
EPIDEMIOLOGY | 347 | ||
CLINICAL MANIFESTATIONS | 347 | ||
LABORATORY EVALUATION | 348 | ||
DIFFERENTIAL DIAGNOSIS | 348 | ||
TREATMENT | 349 | ||
COMPLICATIONS AND PROGNOSIS | 349 | ||
PREVENTION | 349 | ||
Chapter 104 - SINUSITIS | 350 | ||
ETIOLOGY | 350 | ||
EPIDEMIOLOGY | 350 | ||
CLINICAL MANIFESTATIONS | 350 | ||
LABORATORY AND IMAGING STUDIES | 350 | ||
DIFFERENTIAL DIAGNOSIS | 350 | ||
TREATMENT | 350 | ||
COMPLICATIONS AND PROGNOSIS | 350 | ||
PREVENTION | 351 | ||
Chapter 105 - OTITIS MEDIA | 351 | ||
ETIOLOGY | 351 | ||
EPIDEMIOLOGY | 351 | ||
CLINICAL MANIFESTATIONS | 351 | ||
LABORATORY AND IMAGING STUDIES | 351 | ||
DIFFERENTIAL DIAGNOSIS | 352 | ||
TREATMENT | 352 | ||
COMPLICATIONS AND PROGNOSIS | 352 | ||
PREVENTION | 352 | ||
Chapter 106 - OTITIS EXTERNA | 353 | ||
ETIOLOGY | 353 | ||
EPIDEMIOLOGY | 353 | ||
CLINICAL MANIFESTATIONS | 353 | ||
LABORATORY AND IMAGING STUDIES | 353 | ||
DIFFERENTIAL DIAGNOSIS | 353 | ||
TREATMENT | 353 | ||
COMPLICATIONS AND PROGNOSIS | 353 | ||
Chapter 107 - CROUP (LARYNGOTRACHEOBRONCHITIS) | 354 | ||
ETIOLOGY AND EPIDEMIOLOGY | 354 | ||
CLINICAL MANIFESTATIONS | 354 | ||
LABORATORY AND IMAGING STUDIES | 354 | ||
DIFFERENTIAL DIAGNOSIS | 354 | ||
TREATMENT | 354 | ||
PREVENTION | 354 | ||
COMPLICATIONS AND PROGNOSIS | 356 | ||
PREVENTION | 356 | ||
Chapter 108 - PERTUSSIS | 356 | ||
ETIOLOGY | 356 | ||
EPIDEMIOLOGY | 356 | ||
CLINICAL MANIFESTATIONS | 356 | ||
LABORATORY AND IMAGING STUDIES | 356 | ||
DIFFERENTIAL DIAGNOSIS | 357 | ||
TREATMENT | 357 | ||
COMPLICATIONS AND PROGNOSIS | 357 | ||
PREVENTION | 357 | ||
Chapter 109 - BRONCHIOLITIS | 357 | ||
ETIOLOGY | 357 | ||
EPIDEMIOLOGY | 357 | ||
CLINICAL MANIFESTATIONS | 357 | ||
Chapter 110 - PNEUMONIA | 358 | ||
ETIOLOGY | 358 | ||
LABORATORY AND IMAGING STUDIES | 358 | ||
DIFFERENTIAL DIAGNOSIS | 358 | ||
TREATMENT | 358 | ||
COMPLICATIONS AND PROGNOSIS | 358 | ||
PREVENTION | 358 | ||
EPIDEMIOLOGY | 359 | ||
CLINICAL MANIFESTATIONS | 359 | ||
LABORATORY AND IMAGING STUDIES | 361 | ||
DIFFERENTIAL DIAGNOSIS | 362 | ||
TREATMENT | 362 | ||
COMPLICATIONS AND PROGNOSIS | 363 | ||
PREVENTION | 363 | ||
Chapter 111 - INFECTIVE ENDOCARDITIS | 364 | ||
ETIOLOGY | 364 | ||
EPIDEMIOLOGY | 364 | ||
CLINICAL MANIFESTATIONS | 364 | ||
LABORATORY STUDIES AND IMAGING | 364 | ||
DIFFERENTIAL DIAGNOSIS | 365 | ||
TREATMENT | 365 | ||
COMPLICATIONS AND PROGNOSIS | 365 | ||
PREVENTION | 366 | ||
Chapter 112 - ACUTE GASTROENTERITIS | 366 | ||
ETIOLOGY AND EPIDEMIOLOGY | 366 | ||
CLINICAL MANIFESTATIONS | 367 | ||
LABORATORY AND IMAGING STUDIES | 368 | ||
DIFFERENTIAL DIAGNOSIS | 368 | ||
TREATMENT | 368 | ||
COMPLICATIONS AND PROGNOSIS | 369 | ||
PREVENTION | 369 | ||
Chapter 113 - VIRAL HEPATITIS | 369 | ||
ETIOLOGY | 369 | ||
EPIDEMIOLOGY | 369 | ||
CLINICAL MANIFESTATIONS | 370 | ||
LABORATORY AND IMAGING STUDIES | 370 | ||
DIFFERENTIAL DIAGNOSIS | 371 | ||
TREATMENT | 371 | ||
Chapter 114 - URINARY TRACT INFECTION | 372 | ||
ETIOLOGY | 372 | ||
COMPLICATIONS AND PROGNOSIS | 372 | ||
PREVENTION | 372 | ||
EPIDEMIOLOGY | 373 | ||
CLINICAL MANIFESTATIONS | 373 | ||
LABORATORY AND IMAGING STUDIES | 373 | ||
DIFFERENTIAL DIAGNOSIS | 373 | ||
TREATMENT | 373 | ||
Chapter 115 - VULVOVAGINITIS | 374 | ||
ETIOLOGY | 374 | ||
EPIDEMIOLOGY | 374 | ||
CLINICAL MANIFESTATIONS | 374 | ||
LABORATORY AND IMAGING STUDIES | 374 | ||
DIFFERENTIAL DIAGNOSIS | 374 | ||
TREATMENT | 374 | ||
COMPLICATIONS AND PROGNOSIS | 374 | ||
PREVENTION | 374 | ||
COMPLICATIONS AND PROGNOSIS | 375 | ||
PREVENTION | 375 | ||
Chapter 116 - SEXUALLY TRANSMITTED INFECTIONS | 376 | ||
PELVIC INFLAMMATORY DISEASE | 379 | ||
GONORRHEA (NEISSERIA GONORRHOEAE) | 379 | ||
CHLAMYDIA (CHLAMYDIA TRACHOMATIS) | 379 | ||
SYPHILIS (TREPONEMA PALLIDUM) | 380 | ||
HERPES SIMPLEX VIRUS (HSV) INFECTION | 380 | ||
TRICHOMONIASIS (TRICHOMONAS VAGINALIS) | 381 | ||
GENITAL WARTS (HUMAN PAPILLOMAVIRUSES) | 381 | ||
PUBIC LICE (PHTHIRUS PUBIS) | 381 | ||
Chapter 117 - OSTEOMYELITIS | 381 | ||
ETIOLOGY | 381 | ||
EPIDEMIOLOGY | 382 | ||
CLINICAL MANIFESTATIONS | 382 | ||
LABORATORY AND IMAGING STUDIES | 382 | ||
DIFFERENTIAL DIAGNOSIS | 383 | ||
TREATMENT | 383 | ||
Chapter 118 - INFECTIOUS ARTHRITIS | 384 | ||
ETIOLOGY | 384 | ||
EPIDEMIOLOGY | 384 | ||
CLINICAL MANIFESTATIONS | 384 | ||
COMPLICATIONS AND PROGNOSIS | 384 | ||
PREVENTION | 384 | ||
LABORATORY AND IMAGING STUDIES | 385 | ||
DIFFERENTIAL DIAGNOSIS | 385 | ||
TREATMENT | 386 | ||
COMPLICATIONS AND PROGNOSIS | 386 | ||
PREVENTION | 386 | ||
Chapter 119 - OCULAR INFECTIONS | 386 | ||
ETIOLOGY | 386 | ||
EPIDEMIOLOGY | 387 | ||
CLINICAL MANIFESTATIONS | 387 | ||
LABORATORY AND IMAGING STUDIES | 387 | ||
DIFFERENTIAL DIAGNOSIS | 387 | ||
TREATMENT | 389 | ||
COMPLICATIONS AND PROGNOSIS | 389 | ||
PREVENTION | 389 | ||
Chapter 120 - INFECTION IN THE IMMUNOCOMPROMISED PERSON | 390 | ||
ETIOLOGY | 390 | ||
EPIDEMIOLOGY | 391 | ||
CLINICAL MANIFESTATIONS | 391 | ||
LABORATORY TESTS AND IMAGING | 391 | ||
DIFFERENTIAL DIAGNOSIS | 391 | ||
TREATMENT | 391 | ||
PREVENTION | 394 | ||
Chapter 121 - INFECTIONS ASSOCIATED WITH MEDICAL DEVICES | 394 | ||
VASCULAR DEVICE INFECTIONS | 394 | ||
VENTILATOR-ASSOCIATED PNEUMONIA | 395 | ||
URINARY CATHETERS | 395 | ||
PERITONEAL DIALYSIS–ASSOCIATED INFECTIONS | 396 | ||
CENTRAL NERVOUS SYSTEM SHUNTS | 396 | ||
Chapter 122 - ZOONOSES | 396 | ||
LYME DISEASE (BORRELIA BURGDORFERI) | 396 | ||
ROCKY MOUNTAIN SPOTTED FEVER (RICKETTSIA RICKETTSII) | 401 | ||
EHRLICHIOSIS (EHRLICHIA CHAFFEENSIS) AND ANAPLASMOSIS (ANAPLASMA PHAGOCYTOPHILUM) | 401 | ||
Chapter 123 - PARASITIC DISEASES | 402 | ||
PROTOZOAL DISEASES | 402 | ||
HELMINTHIASES | 404 | ||
Chapter 124 - TUBERCULOSIS | 407 | ||
ETIOLOGY | 407 | ||
EPIDEMIOLOGY | 408 | ||
CLINICAL MANIFESTATIONS | 408 | ||
LABORATORY AND IMAGING STUDIES | 409 | ||
DIFFERENTIAL DIAGNOSIS | 410 | ||
TREATMENT | 410 | ||
COMPLICATIONS AND PROGNOSIS | 411 | ||
PREVENTION | 411 | ||
Chapter 125 - HIV AND AIDS | 412 | ||
ETIOLOGY | 412 | ||
EPIDEMIOLOGY | 412 | ||
CLINICAL MANIFESTATIONS | 412 | ||
LABORATORY AND IMAGING STUDIES | 413 | ||
DIFFERENTIAL DIAGNOSIS | 413 | ||
TREATMENT | 413 | ||
COMPLICATIONS | 415 | ||
PROGNOSIS | 415 | ||
PREVENTION | 416 | ||
Suggested Reading | 416 | ||
Section 17 - The Digestive System | 417 | ||
Chapter 126 - ASSESSMENT | 417 | ||
HISTORY | 417 | ||
PHYSICAL EXAMINATION | 417 | ||
SCREENING TESTS | 417 | ||
DIAGNOSTIC IMAGING | 417 | ||
COMMON MANIFESTATIONS OF GASTROINTESTINAL DISORDERS | 417 | ||
Chapter 127 - ORAL CAVITY | 429 | ||
EFFECTS OF SYSTEMIC DISEASE ON THE ORAL CAVITY | 429 | ||
DECIDUOUS AND PRIMARY TEETH | 429 | ||
DENTAL CARIES | 429 | ||
Chapter 128 - ESOPHAGUS AND STOMACH | 430 | ||
GASTROESOPHAGEAL REFLUX | 430 | ||
CLEFT LIP AND PALATE | 430 | ||
THRUSH | 430 | ||
EOSINOPHILIC ESOPHAGITIS (EOE) | 431 | ||
ESOPHAGEAL ATRESIA AND TRACHEOESOPHAGEAL FISTULA | 433 | ||
ESOPHAGEAL FOREIGN BODIES | 434 | ||
CAUSTIC INJURIES AND PILL ULCERS | 434 | ||
PYLORIC STENOSIS | 435 | ||
PEPTIC DISEASE | 436 | ||
CYCLIC VOMITING SYNDROME | 437 | ||
Chapter 129 - INTESTINAL TRACT | 437 | ||
MIDGUT MALROTATION | 437 | ||
INTESTINAL ATRESIA | 438 | ||
OTHER CONGENITAL DISORDERS | 439 | ||
INFLAMMATORY BOWEL DISEASE (IBD) | 440 | ||
CELIAC DISEASE | 442 | ||
MILK AND SOY PROTEIN INTOLERANCE (ALLERGIC COLITIS) | 442 | ||
INTUSSUSCEPTION | 442 | ||
APPENDICITIS | 443 | ||
Chapter 130 - LIVER DISEASE | 444 | ||
CHOLESTASIS | 444 | ||
VIRAL HEPATITIS | 447 | ||
FULMINANT LIVER FAILURE | 447 | ||
CHRONIC LIVER DISEASE | 448 | ||
SELECTED CHRONIC HEPATIC DISORDERS | 449 | ||
Chapter 131 - PANCREATIC DISEASE | 450 | ||
PANCREATIC INSUFFICIENCY | 450 | ||
ACUTE PANCREATITIS | 451 | ||
CHRONIC PANCREATITIS | 452 | ||
Chapter 132 - PERITONITIS | 453 | ||
Suggested Reading | 454 | ||
Section 18 - The Respiratory System | 455 | ||
Chapter 133 - RESPIRATORY SYSTEM ASSESSMENT | 455 | ||
ANATOMY OF THE RESPIRATORY SYSTEM | 455 | ||
PULMONARY PHYSIOLOGY | 455 | ||
HISTORY | 457 | ||
PHYSICAL EXAMINATION | 457 | ||
DIAGNOSTIC MEASURES | 458 | ||
THERAPEUTIC MEASURES | 460 | ||
Chapter 134 - CONTROL OF BREATHING | 461 | ||
CONTROL OF VENTILATION | 461 | ||
DISORDERS OF CONTROL OF BREATHING | 461 | ||
Chapter 135 - UPPER AIRWAY OBSTRUCTION | 464 | ||
ETIOLOGY | 464 | ||
CLINICAL MANIFESTATIONS | 464 | ||
DIAGNOSTIC STUDIES | 464 | ||
DIFFERENTIAL DIAGNOSIS | 467 | ||
Chapter 136 - LOWER AIRWAY, PARENCHYMAL, AND PULMONARY VASCULAR DISEASES | 469 | ||
ETIOLOGY | 469 | ||
CLINICAL MANIFESTATIONS | 469 | ||
DIAGNOSTIC STUDIES | 469 | ||
DIFFERENTIAL DIAGNOSIS | 470 | ||
Chapter 137 - CYSTIC FIBROSIS | 475 | ||
ETIOLOGY AND EPIDEMIOLOGY | 475 | ||
CLINICAL MANIFESTATIONS | 475 | ||
DIAGNOSTIC STUDIES | 476 | ||
TREATMENT | 477 | ||
Chapter 138 - CHEST WALL AND PLEURA | 478 | ||
SCOLIOSIS | 478 | ||
PECTUS EXCAVATUM AND CARINATUM | 478 | ||
PNEUMOTHORAX | 478 | ||
PNEUMOMEDIASTINUM | 479 | ||
PLEURAL EFFUSION | 479 | ||
Suggested Reading | 480 | ||
Section 19 - The Cardiovascular System | 481 | ||
Chapter 139 - CARDIOVASCULAR SYSTEM ASSESSMENT | 481 | ||
HISTORY | 481 | ||
PHYSICAL EXAMINATION | 481 | ||
LABORATORY AND IMAGING TESTS | 484 | ||
Chapter 140 - SYNCOPE | 486 | ||
ETIOLOGY | 486 | ||
CLINICAL MANIFESTATIONS | 486 | ||
DIAGNOSTIC STUDIES | 487 | ||
Chapter 141 - CHEST PAIN | 487 | ||
ETIOLOGY | 487 | ||
Chapter 142 - DYSRHYTHMIAS | 488 | ||
ETIOLOGY AND DIFFERENTIAL DIAGNOSIS | 488 | ||
CLINICAL MANIFESTATIONS | 488 | ||
DIAGNOSTIC STUDIES | 488 | ||
TREATMENT | 490 | ||
Chapter 143 - ACYANOTIC CONGENITAL HEART DISEASE | 491 | ||
ETIOLOGY AND EPIDEMIOLOGY | 491 | ||
VENTRICULAR SEPTAL DEFECT | 491 | ||
ATRIAL SEPTAL DEFECT | 492 | ||
PATENT DUCTUS ARTERIOSUS | 492 | ||
ENDOCARDIAL CUSHION DEFECT | 493 | ||
PULMONARY STENOSIS | 493 | ||
AORTIC STENOSIS | 494 | ||
COARCTATION OF THE AORTA | 494 | ||
Chapter 144 - CYANOTIC CONGENITAL HEART DISEASE | 495 | ||
TETRALOGY OF FALLOT | 495 | ||
TRANSPOSITION OF THE GREAT ARTERIES | 496 | ||
TRICUSPID ATRESIA | 497 | ||
TRUNCUS ARTERIOSUS | 497 | ||
TOTAL ANOMALOUS PULMONARY VENOUS RETURN | 498 | ||
HYPOPLASTIC LEFT HEART SYNDROME | 498 | ||
COMPLICATIONS OF CONGENITAL HEART DISEASE | 499 | ||
Chapter 145 - HEART FAILURE | 499 | ||
ETIOLOGY AND EPIDEMIOLOGY | 499 | ||
Section 20 - Hematology | 506 | ||
Chapter 149 - HEMATOLOGY ASSESSMENT: AVAILABLE @ STUDENTCONSULT.COM | 506 | ||
HISTORY | 506 | ||
PHYSICAL EXAMINATION AND COMMON MANIFESTATIONS | 506 | ||
INITIAL DIAGNOSTIC EVALUATION | 506 | ||
DEVELOPMENTAL HEMATOLOGY | 506 | ||
Chapter 150 - ANEMIA | 509 | ||
ETIOLOGY | 509 | ||
CLINICAL MANIFESTATIONS | 510 | ||
LABORATORY STUDIES | 511 | ||
DIFFERENTIAL DIAGNOSIS | 513 | ||
Chapter 151 - HEMOSTATIC DISORDERS | 523 | ||
NORMAL HEMOSTASIS | 523 | ||
DEVELOPMENTAL HEMOSTASIS | 523 | ||
HEMOSTATIC DISORDERS | 523 | ||
Chapter 152 - BLOOD COMPONENT THERAPY | 532 | ||
Suggested Reading | 533 | ||
Section 21 - Oncology | 534 | ||
Chapter 153 - ONCOLOGY ASSESSMENT | 534 | ||
HISTORY | 534 | ||
PHYSICAL EXAMINATION | 534 | ||
COMMON MANIFESTATIONS | 534 | ||
DIFFERENTIAL DIAGNOSIS | 535 | ||
INITIAL DIAGNOSTIC EVALUATION | 535 | ||
Chapter 154 - PRINCIPLES OF CANCER TREATMENT | 538 | ||
ONCOLOGIC EMERGENCIES | 538 | ||
SURGERY | 538 | ||
CHEMOTHERAPY | 539 | ||
RADIATION THERAPY | 541 | ||
OTHER THERAPIES | 541 | ||
ADVERSE EFFECTS | 541 | ||
Chapter 155 - LEUKEMIA | 542 | ||
ETIOLOGY | 542 | ||
EPIDEMIOLOGY | 542 | ||
CLINICAL MANIFESTATIONS | 542 | ||
LABORATORY AND IMAGING STUDIES | 543 | ||
DIFFERENTIAL DIAGNOSIS | 543 | ||
TREATMENT | 543 | ||
COMPLICATIONS | 544 | ||
PROGNOSIS | 544 | ||
Chapter 156 - LYMPHOMA | 544 | ||
ETIOLOGY | 544 | ||
EPIDEMIOLOGY | 545 | ||
CLINICAL MANIFESTATIONS | 545 | ||
LABORATORY/IMAGING STUDIES | 545 | ||
DIFFERENTIAL DIAGNOSIS | 545 | ||
TREATMENT | 545 | ||
COMPLICATIONS | 546 | ||
PROGNOSIS | 546 | ||
Chapter 157 - CENTRAL NERVOUS SYSTEM TUMORS | 546 | ||
ETIOLOGY | 546 | ||
EPIDEMIOLOGY | 546 | ||
CLINICAL MANIFESTATIONS | 546 | ||
LABORATORY/IMAGING STUDIES | 547 | ||
DIFFERENTIAL DIAGNOSIS | 547 | ||
TREATMENT | 547 | ||
COMPLICATIONS | 547 | ||
PROGNOSIS | 547 | ||
Chapter 158 - NEUROBLASTOMA | 548 | ||
ETIOLOGY | 548 | ||
EPIDEMIOLOGY | 548 | ||
CLINICAL MANIFESTATIONS | 548 | ||
LABORATORY/IMAGING STUDIES | 548 | ||
DIFFERENTIAL DIAGNOSIS | 548 | ||
TREATMENT | 549 | ||
COMPLICATIONS | 549 | ||
PROGNOSIS | 549 | ||
Chapter 159 - WILMS TUMOR | 550 | ||
ETIOLOGY | 550 | ||
EPIDEMIOLOGY | 550 | ||
CLINICAL MANIFESTATIONS | 550 | ||
LABORATORY/IMAGING STUDIES | 550 | ||
DIFFERENTIAL DIAGNOSIS | 550 | ||
TREATMENT | 550 | ||
COMPLICATIONS | 550 | ||
PROGNOSIS | 550 | ||
Chapter 160 - SARCOMAS | 551 | ||
ETIOLOGY | 551 | ||
EPIDEMIOLOGY | 551 | ||
CLINICAL MANIFESTATIONS | 551 | ||
LABORATORY/IMAGING STUDIES | 551 | ||
DIFFERENTIAL DIAGNOSIS | 552 | ||
TREATMENT | 552 | ||
COMPLICATIONS | 552 | ||
PROGNOSIS | 552 | ||
Suggested Reading | 552 | ||
Section 22 - Nephrology and Urology | 553 | ||
Chapter 161 - NEPHROLOGY AND UROLOGY ASSESSMENT | 553 | ||
HISTORY | 553 | ||
PHYSICAL EXAMINATION | 553 | ||
RENAL PHYSIOLOGY | 553 | ||
COMMON MANIFESTATIONS | 554 | ||
DIAGNOSTIC STUDIES | 555 | ||
Chapter 162 - NEPHROTIC SYNDROME AND PROTEINURIA | 556 | ||
ETIOLOGY AND EPIDEMIOLOGY | 556 | ||
IMAGING STUDIES | 556 | ||
CLINICAL MANIFESTATIONS | 557 | ||
DIAGNOSTIC STUDIES | 557 | ||
DIFFERENTIAL DIAGNOSIS | 557 | ||
TREATMENT | 557 | ||
COMPLICATIONS | 557 | ||
PROGNOSIS | 558 | ||
Chapter 163 - GLOMERULONEPHRITIS AND HEMATURIA | 558 | ||
ETIOLOGY AND EPIDEMIOLOGY | 558 | ||
CLINICAL MANIFESTATIONS | 558 | ||
DIAGNOSTIC STUDIES | 559 | ||
THERAPY | 559 | ||
PROGNOSIS AND PREVENTION | 560 | ||
Chapter 164 - HEMOLYTIC UREMIC SYNDROME | 560 | ||
ETIOLOGY AND EPIDEMIOLOGY | 560 | ||
CLINICAL MANIFESTATIONS | 560 | ||
DIAGNOSTIC STUDIES | 560 | ||
TREATMENT AND PROGNOSIS | 560 | ||
Chapter 165 - ACUTE AND CHRONIC RENAL FAILURE | 561 | ||
ACUTE KIDNEY INJURY | 561 | ||
CHRONIC KIDNEY DISEASE | 562 | ||
Chapter 166 - HYPERTENSION | 563 | ||
DEFINITION | 563 | ||
ETIOLOGY | 563 | ||
CLINICAL MANIFESTATIONS | 563 | ||
Chapter 167 - VESICOURETERAL REFLUX | 564 | ||
ETIOLOGY AND EPIDEMIOLOGY | 564 | ||
DIAGNOSTIC STUDIES | 564 | ||
TREATMENT | 564 | ||
PROGNOSIS | 564 | ||
CLINICAL MANIFESTATIONS | 565 | ||
DIAGNOSTIC STUDIES | 565 | ||
TREATMENT | 565 | ||
Chapter 168 - CONGENITAL AND DEVELOPMENTAL ABNORMALITIES OF THE URINARY TRACT | 565 | ||
ETIOLOGY AND EPIDEMIOLOGY | 565 | ||
CLINICAL MANIFESTATIONS | 566 | ||
DIAGNOSTIC IMAGING | 566 | ||
Chapter 169 - OTHER URINARY TRACT AND GENITAL DISORDERS | 567 | ||
URINARY TRACT STONES | 567 | ||
VOIDING DYSFUNCTION | 567 | ||
TREATMENT | 567 | ||
ANOMALIES OF THE PENIS | 568 | ||
DISORDERS AND ABNORMALITIES OF THE SCROTUM AND ITS CONTENTS | 568 | ||
ACKNOWLEDGMENT | 569 | ||
Suggested Reading | 569 | ||
Section 23 - Endocrinology | 570 | ||
Chapter 170 - ENDOCRINOLOGY ASSESSMENT | 570 | ||
HYPOTHALAMIC-PITUITARY AXIS | 570 | ||
DISORDERS OF THE HYPOTHALAMIC-PITUITARY AXIS | 571 | ||
Chapter 171 - DIABETES MELLITUS | 572 | ||
DEFINITION | 572 | ||
INSULIN-DEPENDENT (TYPE 1) DIABETES MELLITUS | 573 | ||
DIABETIC KETOACIDOSIS | 573 | ||
NON-INSULIN−DEPENDENT (TYPE 2) DIABETES MELLITUS | 578 | ||
MATURITY-ONSET DIABETES OF YOUTH (MODY) | 579 | ||
Chapter 172 - HYPOGLYCEMIA | 579 | ||
DEFINITION | 579 | ||
CLINICAL MANIFESTATIONS | 579 | ||
PATHOPHYSIOLOGY | 580 | ||
ENERGY STORES | 582 | ||
IDIOPATHIC KETOTIC HYPOGLYCEMIA | 582 | ||
DISRUPTED METABOLIC RESPONSE PATHWAYS | 582 | ||
OTHER METABOLIC DISORDERS | 582 | ||
MEDICATIONS AND INTOXICATION | 582 | ||
Chapter 173 - SHORT STATURE | 583 | ||
GROWTH | 583 | ||
DIAGNOSIS | 583 | ||
EMERGENCY MANAGEMENT | 583 | ||
ABNORMALITIES OF GROWTH | 584 | ||
Chapter 174 - DISORDERS OF PUBERTY | 589 | ||
PHYSIOLOGY | 589 | ||
DELAYED PUBERTY | 589 | ||
SEXUAL PRECOCITY | 592 | ||
Chapter 175 - THYROID DISEASE | 596 | ||
THYROID PHYSIOLOGY AND DEVELOPMENT | 596 | ||
VARIATIONS IN PUBERTAL DEVELOPMENT | 596 | ||
THYROID DISORDERS | 598 | ||
NODULES/TUMORS OF THE THYROID | 601 | ||
Chapter 176 - DISORDERS OF PARATHYROID BONE AND MINERAL ENDOCRINOLOGY | 602 | ||
PARATHYROID HORMONE AND VITAMIN D | 602 | ||
HYPOCALCEMIA | 602 | ||
RICKETS | 603 | ||
Chapter 177 - DISORDERS OF SEXUAL DEVELOPMENT | 604 | ||
NORMAL SEXUAL DEVELOPMENT | 604 | ||
ABNORMAL SEXUAL DEVELOPMENT | 605 | ||
APPROACH TO THE INFANT WITH GENITAL AMBIGUITY | 606 | ||
Chapter 178 - ADRENAL GLAND DYSFUNCTION | 607 | ||
PHYSIOLOGY | 607 | ||
ADRENAL INSUFFICIENCY | 608 | ||
21-HYDROXYLASE DEFICIENCY | 609 | ||
OTHER ENZYME DEFECTS | 611 | ||
ADDISON DISEASE | 611 | ||
CUSHING SYNDROME | 611 | ||
Suggested Reading | 611 | ||
Section 24 - Neurology | 612 | ||
Chapter 179 - NEUROLOGY ASSESSMENT | 612 | ||
HISTORY | 612 | ||
PHYSICAL EXAMINATION | 612 | ||
NEUROLOGIC EXAMINATION OF A NEONATE | 612 | ||
NEUROLOGIC EXAMINATION OF A CHILD | 613 | ||
CRANIAL NERVE EVALUATION | 613 | ||
MOTOR EXAMINATION | 614 | ||
SENSORY EXAMINATION | 615 | ||
SPECIAL DIAGNOSTIC PROCEDURES | 615 | ||
Chapter 180 - HEADACHE AND MIGRAINE | 616 | ||
ETIOLOGY AND EPIDEMIOLOGY | 616 | ||
CLINICAL MANIFESTATIONS | 617 | ||
DIAGNOSTIC STUDIES | 617 | ||
Chapter 181 - SEIZURES (PAROXYSMAL DISORDERS) | 618 | ||
ETIOLOGY AND EPIDEMIOLOGY | 618 | ||
FOCAL SEIZURES | 618 | ||
TREATMENT | 618 | ||
GENERALIZED SEIZURES | 619 | ||
EPILEPSY SYNDROMES | 621 | ||
STATUS EPILEPTICUS | 621 | ||
LABORATORY AND DIAGNOSTIC EVALUATION | 622 | ||
LONG-TERM THERAPY | 622 | ||
Chapter 182 - WEAKNESS AND HYPOTONIA | 623 | ||
ETIOLOGY | 623 | ||
CLINICAL MANIFESTATIONS | 623 | ||
DISEASE OF THE UPPER MOTOR NEURON | 624 | ||
DISEASES OF THE SPINAL CORD | 624 | ||
DISEASES OF THE LOWER MOTOR NEURON | 624 | ||
STROKE IN CHILDHOOD | 630 | ||
Chapter 183 - ATAXIA AND MOVEMENT DISORDERS | 631 | ||
ATAXIA | 631 | ||
MOVEMENT DISORDERS | 633 | ||
Chapter 184 - ALTERED MENTAL STATUS | 634 | ||
DISORDERS OF CONSCIOUSNESS | 634 | ||
TRAUMATIC BRAIN INJURY | 637 | ||
INCREASED INTRACRANIAL PRESSURE | 640 | ||
Chapter 185 - NEURODEGENERATIVE DISORDERS | 642 | ||
HEREDITARY AND METABOLIC DEGENERATIVE DISEASES | 642 | ||
ACQUIRED ILLNESSES MIMICKING DEGENERATIVE DISEASES | 645 | ||
Chapter 186 - NEUROCUTANEOUS DISORDERS | 645 | ||
NEUROFIBROMATOSIS TYPE 1 | 645 | ||
TUBEROUS SCLEROSIS COMPLEX | 646 | ||
STURGE-WEBER SYNDROME | 646 | ||
Chapter 187 - CONGENITAL MALFORMATIONS OF THE CENTRAL NERVOUS SYSTEM | 647 | ||
CONGENITAL ANOMALIES OF THE SPINAL CORD | 647 | ||
CONGENITAL MALFORMATIONS OF THE BRAIN | 647 | ||
ACKNOWLEDGMENT | 649 | ||
Suggested Reading | 649 | ||
Section 25 - Dermatology | 650 | ||
Chapter 188 - ASSESSMENT | 650 | ||
HISTORY | 650 | ||
PHYSICAL EXAMINATION | 650 | ||
COMMON MANIFESTATIONS | 650 | ||
INITIAL DIAGNOSTIC EVALUATION AND TESTS | 651 | ||
Chapter 189 - ACNE | 652 | ||
ETIOLOGY | 652 | ||
EPIDEMIOLOGY | 652 | ||
CLINICAL MANIFESTATIONS | 652 | ||
TREATMENT | 652 | ||
COMPLICATIONS | 652 | ||
PROGNOSIS | 652 | ||
PREVENTION | 653 | ||
Chapter 190 - ATOPIC DERMATITIS | 653 | ||
ETIOLOGY | 653 | ||
EPIDEMIOLOGY | 653 | ||
CLINICAL MANIFESTATIONS | 653 | ||
LABORATORY AND IMAGING STUDIES | 654 | ||
DIFFERENTIAL DIAGNOSIS | 654 | ||
TREATMENT | 654 | ||
COMPLICATIONS | 655 | ||
Chapter 191 - CONTACT DERMATITIS | 656 | ||
ETIOLOGY AND EPIDEMIOLOGY | 656 | ||
CLINICAL MANIFESTATIONS | 656 | ||
LABORATORY AND IMAGING STUDIES | 656 | ||
PROGNOSIS | 656 | ||
PREVENTION | 656 | ||
DIFFERENTIAL DIAGNOSIS | 657 | ||
TREATMENT | 657 | ||
COMPLICATIONS | 657 | ||
PREVENTION | 657 | ||
Chapter 192 - SEBORRHEIC DERMATITIS | 657 | ||
ETIOLOGY | 657 | ||
CLINICAL MANIFESTATIONS | 657 | ||
LABORATORY AND IMAGING STUDIES | 658 | ||
DIFFERENTIAL DIAGNOSIS | 658 | ||
TREATMENT | 658 | ||
PROGNOSIS | 658 | ||
PREVENTION | 658 | ||
OTHER PAPULOSQUAMOUS DERMATOSES | 658 | ||
Chapter 193 - PIGMENTED LESIONS | 659 | ||
DERMAL MELANOSIS | 659 | ||
CAFÉ AU LAIT MACULES | 659 | ||
CONGENITAL MELANOCYTIC NEVI | 660 | ||
CONGENITAL GIANT MELANOCYTIC NEVI | 660 | ||
ACQUIRED NEVI | 661 | ||
Chapter 194 - VASCULAR ANOMALIES | 661 | ||
VASCULAR TUMORS | 661 | ||
Chapter 195 - ERYTHEMA MULTIFORME, STEVENS-JOHNSON SYNDROME, AND TOXIC EPIDERMAL NECROLYSIS | 662 | ||
VASCULAR MALFORMATIONS | 662 | ||
ERYTHEMA MULTIFORME | 663 | ||
STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS | 664 | ||
Chapter 196 - CUTANEOUS INFESTATIONS | 664 | ||
SCABIES | 664 | ||
PEDICULOSES | 665 | ||
Suggested Reading | 666 | ||
Section 26 - Orthopedics | 667 | ||
Chapter 197 - ORTHOPEDICS ASSESSMENT | 667 | ||
GROWTH AND DEVELOPMENT | 667 | ||
DEVELOPMENTAL MILESTONES | 668 | ||
Chapter 198 - FRACTURES | 670 | ||
PEDIATRIC FRACTURE PATTERNS | 670 | ||
MANAGEMENT OF PEDIATRIC FRACTURES | 671 | ||
SPECIAL CONCERNS | 671 | ||
Chapter 199 - HIP | 672 | ||
DEVELOPMENTAL DYSPLASIA OF THE HIP | 672 | ||
TRANSIENT MONOARTICULAR SYNOVITIS | 674 | ||
LEGG-CALVE-PERTHES DISEASE | 674 | ||
SLIPPED CAPITAL FEMORAL EPIPHYSIS | 675 | ||
Chapter 200 - LOWER EXTREMITY AND KNEE | 676 | ||
TORSIONAL VARIATIONS | 676 | ||
ANGULAR VARIATIONS | 677 | ||
LEG-LENGTH DISCREPANCY | 678 | ||
KNEE | 679 | ||
Chapter 201 - FOOT | 681 | ||
CLUB FOOT (TALIPES EQUINOVARUS) | 681 | ||
METATARSUS ADDUCTUS | 682 | ||
CALCANEOVALGUS FOOT | 682 | ||
HYPERMOBILE PES PLANUS (FLEXIBLE FLATFOOT) | 682 | ||
TARSAL COALITION | 682 | ||
CAVUS FOOT | 683 | ||
IDIOPATHIC AVASCULAR NECROSIS | 683 | ||
SEVER DISEASE (CALCANEAL APOPHYSITIS) | 683 | ||
TOE DEFORMITIES | 683 | ||
Chapter 202 - SPINE | 684 | ||
SPINAL DEFORMITIES | 684 | ||
SCOLIOSIS | 685 | ||
KYPHOSIS | 688 | ||
TORTICOLLIS | 688 | ||
BACK PAIN IN CHILDREN | 689 | ||
SPONDYLOLYSIS AND SPONDYLOLISTHESIS | 689 | ||
DISKITIS | 690 | ||
Chapter 203 - UPPER EXTREMITY | 691 | ||
SHOULDER | 691 | ||
ELBOW | 692 | ||
WRIST AND HAND | 693 | ||
Chapter 204 - BENIGN BONE TUMORS AND CYSTIC LESIONS | 693 | ||
Suggested Reading | 694 | ||
Index | 695 | ||
IBC | IBC |