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The Netter Collection of Medical Illustrations: Nervous System, Volume 7, Part 1 - Brain e-Book

The Netter Collection of Medical Illustrations: Nervous System, Volume 7, Part 1 - Brain e-Book

H. Royden Jones, Jr. | Ted Burns | Michael J. Aminoff | Scott Pomeroy

(2013)

Additional Information

Abstract

Brain, Part 1 of The Netter Collection of Medical Illustrations: Nervous System, 2nd Edition, provides a highly visual guide to this complex organ, from basic neurodevelopment, neuroanatomy, neurophysiology, and cognition to classic disorders including to epilepsy, hypothalamus/pituitary with disorders of consciousness and sleep, movement disorders, cerebellum, stroke, multiple sclerosis, neurologic infections, neuro-oncology, headaches, and brain trauma. This spectacularly illustrated volume in the masterwork known as the (CIBA) Netter "Green Books" has been expanded and revised by Drs. H. Royden Jones, Jr., Ted M. Burns, Michael J. Aminoff, and Scott L. Pomeroy to mirror the many exciting advances in medicine and imaging - offering unparalleled insights into the broad clinical spectrum of brain disorders.

  • Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.
  • Get complete, integrated visual guidance on the brain with thorough, richly illustrated coverage.
  • Quickly understand complex topics thanks to a concise text-atlas format that provides a context bridge between primary and specialized medicine.
  • Clearly visualize how core concepts of anatomy, physiology, and other basic sciences correlate across disciplines.
  • Benefit from matchless Netter illustrations that offer precision, clarity, detail and realism as they provide a visual approach to the clinical presentation and care of the patient.
  • Gain a rich clinical view of all aspects of the brain in one comprehensive volume, conveyed through beautiful illustrations as well as up-to-date radiologic images.
  • Clearly see the connection between basic science and clinical practice with an integrated overview of normal structure and function as it relates to pathologic conditions.
  • Grasp current clinical concepts regarding development, pediatrics, and adult medicine captured in classic Netter illustrations, as well as new illustrations created specifically for this volume by artist-physician Carlos Machado, MD, and others working in the Netter style.

Table of Contents

Section Title Page Action Price
Front cover cover
Marketing Ad page i i
Marketing Ad page ii ii
The Netter Collection of Medical Illustrations: Nervous System, Volume 7, Part 1 - Brain iii
Copyright page iv
About the Series v
About the Editors vi
Foreword viii
Preface, Acknowledgments, and Dedication ix
Preface ix
Acknowledgments ix
Dedication ix
Frank Netter, Md: A Personal Recollection x
Introduction to the First Edition xi
Introduction to Part I xi
Introduction to Part II xii
Advisory Board xiii
Contributors xiv
Contents of Complete Volume 7— Nervous System: Two-Part Set xvii
Table of Contents xix
1 Normal and Abnormal Development 1
Initial Specification of the Nervous System: The Embryo at 18 Days 2
Initial Formation of the Brain and Spinal Cord: The Embryo at 20 to 24 Days 3
Morphogenesis of the Brain, Spinal Cord, and Peripheral Nervous System: The Embryo from 28 through 36 Days 4
Defective Neural Tube Formation 6
Spinal Dysraphism 8
Spina Bifida Occulta 8
Spina Bifida Aperta 8
Fetal Brain Growth in the First Trimester 10
Craniosynostosis 11
Extracranial Hemorrhage and Skull Fractures in the Newborn 12
Intracranial Hemorrhage in the Newborn 13
The External Development of the Brain in the Second and Third Trimesters 14
Mature Brain Ventricles 15
Hydrocephalus 16
Surgical Treatment of Hydrocephalus 17
Cerebral Palsy 18
Cerebral Lesions 18
Clinical Manifestations of Cerebral Palsy 18
Treatment 18
Establishing Cellular Diversity in the Embryonic Brain and Spinal Cord 20
Generation of Neuronal Diversity in the Spinal Cord and Hindbrain 22
Circuit Formation in the Spinal Cord 23
Making Peripheral Nerves and Central Tracts 24
Brachial Plexus and/or Cervical Nerve Root Injuries at Birth 26
Morphogenesis and Regional Differentiation of the Forebrain 27
Neurogenesis and Cell Migration in the Developing Neocortex 28
Neuronal Proliferation and Migration Disorders 29
Developmental Dyslexia 30
Autism Spectrum Disorders 31
Clinical Presentation 31
Diagnosis 31
Treatment 31
Course 31
Rett Syndrome 32
Pathophysiology 32
2 Cerebral Cortex and Neurocognitive Disorders 33
Surfaces of Cerebrum 34
Superolateral Surface 34
Medial Surface of Cerebral Hemispheres 35
Inferior Surface of Cerebral Hemisphere 36
Cerebral Cortex: Function and Association Pathways 37
Major Cortical Association Bundles 38
Corticocortical and Subcorticocortical Projection Circuits 39
Corpus Callosum 40
Color Imaging of the Corpus Callosum by Diffusion Tensor Imaging 40
Rhinencephalon and Limbic System 41
Hippocampus 42
Fornix 43
Amygdala 44
Forebrain Regions Associated with Hypothalamus 45
Thalamocortical Radiations 46
Neuronal Structure and Synapses 47
Neuronal Structure 47
Types of Neuronal Synapses 47
Chemical Synaptic Transmission 48
Summation of Excitation and Inhibition 49
Types of Neurons in Cerebral Cortex 50
Astrocytes 51
Testing for Defects of Higher Cortical Function 52
Memory Circuits 53
Amnesia 54
Dominant Hemisphere Language Dysfunction 55
Nondominant Hemisphere Higher Cortical Dysfunction 56
Alzheimer Disease: Pathology 57
Alzheimer Disease: Distribution of Pathology 58
Alzheimer Disease: Clinical Manifestations, Progressive Phases 59
Frontotemporal Dementia 60
Dementia with Lewy Bodies 61
Vascular Dementia 62
Treatable Dementias 63
Normal-Pressure Hydrocephalus 64
3 Epilepsy 65
Electroencephalography 66
Seizures and Epilepsy 67
Focal (Partial) Seizures 67
Generalized Seizures: Tonic-Clonic Seizure 68
Generalized Seizures: Absence (Petit Mal) Seizures 69
Other Generalized Seizures 69
Epileptic Syndromes 70
Neonatal Seizures 71
Status Epilepticus 72
Causes of Seizures 73
Neurobiology of Epilepsy 74
Generalized Seizures 76
Treatment of Epilepsy 77
4 Psychiatry 79
Limbic System 80
Major Depressive Disorder 81
5 Hypothalamus, Pituitary, Sleep, and Thalamus 111
Anatomic Relationships of the Hypothalamus 112
Development and Developmental Disorders of the Hypothalamus 113
Blood Supply of the Hypothalamus and Pituitary Gland 114
Overview of Hypothalamic Cell Groups 115
Hypothalamic Control of the Pituitary Gland 117
Hypothalamic Control of the Autonomic Nervous System 118
Olfactory Inputs to the Hypothalamus 119
Visual Inputs to the Hypothalamus 120
Somatosensory Inputs to the Hypothalamus 121
Taste and Other Visceral Sensory Inputs to the Hypothalamus 122
Limbic and Cortical Inputs to the Hypothalamus 123
Overview of Hypothalamic Function and Dysfunction 124
Regulation of Water Balance 125
Temperature Regulation 126
Fever: Hypothalamic Response to Systemic Inflammation 127
Hypothalamic Control of Lymphoid Tissue in Immune Response 128
Regulation of Food Intake, Body Weight, and Metabolism 129
Stress Response 130
Hypothalamic Regulation of Cardiovascular Function 131
Hypothalamic Regulation of Sleep 132
Narcolepsy: A Hypothalamic Sleep Disorder 133
Sleep-Disordered Breathing 134
Parasomnias 135
Periodic Limb Movements of Sleep (PLMS) 135
Restless Leg Syndrome (RLS) 135
REM Sleep Behavior Disorder 135
Night Terrors, Sleep Walking, and Bed Wetting 135
Divisions of the Pituitary Gland and Its Relationships to the Hypothalamus 136
Posterior Pituitary Gland 137
Anatomic Relationships of the Pituitary Gland 138
Effects of Pituitary Mass Lesions on the Visual Apparatus 139
Anterior Pituitary Hormone Deficiencies 140
Severe Anterior Pituitary Hormone Deficiencies (Panhypopituitarism) 141
Postpartum Pituitary Infarction (Sheehan Syndrome) 142
Pituitary Apoplexy 143
Thalamic Anatomy and Pathology 144
Thalamic Anatomy 144
Thalamic Pathology 145
6 Disorders of Consciousness (Coma) 147
Coma 148
Disorders of Consciousness 149
Emergency Management and Assessment and Neurology Examination 150
Emergency Management and Assessment 150
Neurologic Examination 151
Differential Diagnosis of Coma 152
Treatment 152
Hypoxic-Ischemic Brain Damage 153
Vegetative State and Minimally Conscious State 154
Brain Death 155
Ventilatory Patterns and the Apnea Test 156
7 Basal Ganglia and Movement Disorders 157
8 Cerebellum and Ataxia 177
Cerebellum and the Fourth Ventricle 178
Cerebellum Gross Anatomy 179
Cerebellar Peduncles 180
Cerebellar Cortex and Nuclei 181
Cerebellar Nuclei 182
Cerebellar Cortical and Corticonuclear Circuitry 183
Cerebellum Subdivisions and Afferent Pathways 185
Mossy Fiber Pathways 185
Climbing Fiber Pathways 186
Monoaminergic Fibers 186
Cerebellar Efferent Pathways 187
Fastigial Nucleus 187
Globose and Emboliform Nuclei 188
Dentate Nucleus 188
Cerebellovestibular Pathways 189
Vestibulocerebellar Projections 189
Cerebellovestibular Projections 189
Functional Considerations 189
Cerebellum Modular Organization 190
Cerebellar Corticonuclear Projection 190
Inferior Olivary Nucleus 190
Olivary Afferents and Projections to Cerebellum 190
Cerebrocerebellar Connections 191
Cerebellar Motor Examination 192
Cerebellar Cognitive Affective Syndrome 193
Cerebellar Disorders—Differential Diagnosis 194
Acute—Minutes to Hours 194
Subacute—Days to Weeks 194
Insidious, Chronic Progression—Months to Years 194
Gait Disorders—Differential Diagnosis 195
Friedreich Ataxia 197
9 Cerebrovascular Circulation and Stroke 199
Overview and Approach to Stroke Patient 200
Arterial Supply to the Brain and Meninges 200
Overview and Cervical Segments 200
Internal Carotid Artery 200
Vertebral Artery Extracranial 200
External Carotid Artery 201
Anomalous Origins 201
Supratentorial Arteries to the Brain 201
Circle of Willis 201
Basilar Artery 201
Posterior Cerebral Arteries 202
Ophthalmic, Anterior Choroidal, and Posterior Communicating Arteries 202
Anterior Cerebral Arteries 202
Middle Cerebral Arteries 203
Meningeal Arteries 203
Types of Stroke 204
Hemorrhage 204
Brain Ischemia 205
Timing and Evolution 206
Clinical Evaluation and Treatment of Stroke 206
Uncommon Etiologic Mechanism of Stroke 208
Anterior Circulation Ischemia 209
Etiology 209
Clinical Manifestations 210
Diagnosis 212
Treatment 213
Carotid Artery Atherosclerotic Disease 213
Intracranial ACA/MCA Atherosclerotic Disease 216
Anterior Circulation Dissection 216
Vertebral Basilar System Disorders 217
Subclavian and Innominate Arteries 217
Vertebral Arteries in the Neck 217
Atherosclerosis 217
Vertebral Artery Dissection 217
Intracranial Vertebral Artery Disease 218
Lateral Medullary Syndrome 218
Cerebellar Infarction 219
Medial Medullary Infarction 219
Proximal and Midbasilar Artery Occlusion 219
Top-of-the-Basilar Artery Embolism 220
Thalamic Infarcts 221
Posterior Cerebral Arteries 222
Brain Emboli 223
The Recipient Arteries 223
Donor Sources and Their Embolic Materials 223
Treatment 224
Lacunar Stroke 225
Lacunar Infarcts 225
Chronic Subcortical Vascular Disease 226
Hypertensive Encephalopathy 227
Hypoxia 228
Coagulopathies 229
Role of Platelets in Arterial Thrombosis 229
Inherited Thrombophilias 230
Antiphospholipid Antibody Syndrome 231
Venous Sinus Thrombosis 232
Venous Sinuses of the Dura Mater 232
Posterosuperior Group 232
Anteroinferior Group 232
Cerebral Venous System 233
Superficial Group 233
Deep Group 233
Diagnosis and Treatment of Cerebral Venous Sinus Thrombosis 234
Intracerebral Hemorrhage 235
Cerebellar Hemorrhage 236
Subarachnoid Hemorrhage and Intracranial Aneurysms 238
Pediatric Cerebrovascular Disease 243
Introduction and Initial Stroke Rehabilitation 244
Aphasia Rehabilitation 245
Other Rehabilitative Issues: Dysphagia/Gait Training/Locked-in Syndrome 246
Dysphagia 246
Gait Disorders 246
Locked-in Syndrome 246
10 Multiple Sclerosis and Other Central Nervous System Autoimmune Disorders 247
Multiple Sclerosis: Overview 248
Multiple Sclerosis: Clinical Manifestations 249
Optic Neuritis 249
Brainstem Lesions 249
Cerebellar Ataxia 249
Sensory Symptoms 249
Corticospinal Tract Dysfunction 249
Depression 249
Cognition 249
Multiple Sclerosis: Diagnosis 250
Magnetic Resonance Imaging (MRI) 250
Tumefactive MS 251
Cerebrospinal Fluid (CSF) Analysis 252
Evoked Potentials (EPS) 252
Multiple Sclerosis: Pathophysiology 253
Peripheral Events That Precede a Multiple Sclerosis Relapse 253
Multiple Sclerosis: Relapses 256
Step One 256
Step Two 257
Step Three 257
Step Four 257
Step Five 257
Step Six 258
Step Seven 259
Step Eight 259
Step Nine 259
Evolution of the MS Plaque 259
Enigma of Progressive Multiple Sclerosis 260
Multiple Sclerosis: Pathology 261
Gross Central Nervous System Pathology 261
Histopathology of Multiple Sclerosis 261
Multiple Sclerosis: Treatment 262
Prognosis 262
Interferon-β 262
Glatiramer Acetate 262
Natalizumab 263
Fingolimod 263
Teriflunomide 263
Mitoxantrone: (Novantrone) 263
Dimethyl Fumarate (BG-12) 263
Anti–b-Cell Agents 263
Neuromyelitis Optica, Acute Disseminated Encephalomyelitis, and Acute Hemorrhagic Leukoencephalitis 264
Neuromyelitis Optica 264
Acute Disseminated Encephalomyelitis (ADEM) 264
Acute Hemorrhagic Leukoencephalopathy (AHL) 265
Other Neuroimmunologic Syndromes: an Overlap Between Primary and Paraneoplastic Processes 266
Stiff-Man Syndrome 267
Introduction 267
Etiology 267
Clinical Presentation 267
Differential Diagnosis 267
Treatment 267
Paraneoplastic Immune-Mediated Disorders 268
Neuroimmunology: Paraneoplastic and Other Autoimmune Syndromes 270
Cerebral Cortex and Limbic System 270
Diencephalon 270
Basal Ganglia and Extrapyramidal System 270
Cerebellum 270
Brainstem 271
Cranial Nerves 271
Spinal Cord 271
Motor Neuron or Motor Nerve Syndromes 272
Sensory Neuropathies 272
Autonomic Nervous System 272
Neuromuscular Junction 272
Muscle 272
11 Infections of the Nervous System 273
Bacterial Meningitis 274
Brain Abscess 276
Parameningeal Infections 277
Subdural Empyema 277
Spinal Epidural Abscess 277
Infections in the Immunocompromised Host 278
Neurocysticercosis 280
Spirochetal Infections 281
Neurosyphilis 281
Lyme Disease 282
Tuberculosis of Brain and Spine 283
Tetanus 284
Aseptic Meningitis 285
Select Arthropod-Borne Virus Infections 285
Human Immunodeficiency Virus 286
Poliomyelitis 288
Herpes Zoster 289
Herpes Simplex Virus Encephalitis and Rabies 290
Rabies 290
Parasitic Infections: Cerebral Malaria and African Trypanosomiasis 291
Cerebral Malaria 291
African Trypanosomiasis 291
Parasitic Infections: Trichinosis (Trichinellosis) 292
Parasitic Infections: Cryptococcal Meningitis 293
Creutzfeldt-Jakob Disease 294
Neurosarcoidosis 295
12 Neuro-Oncology 297
Clinical Presentations of Brain Tumors 298
Gliomas 299
Glioblastoma 300
Pediatric Brain Tumors 301
Metastatic Tumors to Brain 303
Meningiomas 304
Pituitary Tumors and Craniopharyngiomas 306
Tumors of Pineal Region 309
Vestibular Schwannomas 310
Intraventricular Tumors 312
Chordomas 313
Differential Diagnosis of Central Nervous System Tumors 314
Treatment Modalities 315
13 Headache 317
Overview of Headaches 318
Migraine Pathophysiology 319
Migraine Presentation 320
Migraine Aura 321
Other Migraine Variants 321
Migraine Management 322
Trigeminal Autonomic Cephalalgias 323
Cluster Headache 323
Sunct/SUNA 323
Paroxysmal Hemicrania 324
Hemicrania Continua 324
Tension-Type Headache and Other Benign Episodic and Chronic Headaches 325
Pediatric Headache 326
Cranial Neuralgias: Trigeminal Neuralgia 327
Other Cranial Neuralgias 328
Glossopharyngeal Neuralgia 328
Occipital Neuralgia 328
Less Common Cranial Neuralgias 328
Idiopathic Intracranial Hypertension (IIH), Pseudotumor Cerebri 329
Intracranial Hypotension/Low Cerebrospinal Fluid–pressure Headache 330
Giant Cell Arteritis 331
Contiguous Structure Headaches 332
sinus headache 332
Temporomandibular Disorder 332
Dental 332
Glaucoma 332
Thunderclap Headache and Other Headache Presenting in the Emergency Department 333
Subarachnoid and Intraparenchymal Hemorrhage 333
Reversible Cerebral Vasoconstriction Syndrome 334
Acute Hypertensive Crisis/Posterior Reversible Encephalopathy Syndrome (PRES) 334
Cerebral Venous Thrombosis 335
Pituitary Apoplexy 335
Colloid Cyst 335
Post-Traumatic Headache 336
Intracranial Infection 336
14 Head Trauma 337
Skull: Anterior and Lateral Aspects 338
Skull: Midsagittal Section 340
Calvaria 341
External Aspect of Skull Base 342
Bones, Markings, and Orifices of Skull Base 343
Skull Injuries 345
Concussion 346
Acute Epidural Hematoma 347
Acute Subdural Hematoma 348
Contusions 348
Diffuse Axonal Injury 348
CT Scans and MR Images of Intracranial Hematomas 349
Vascular Injury 350
Carotid-Cavernous Fistula 350
Secondary Complications of Traumatic Brain Injury 350
Initial Assessment and Management of Head Injury 351
Glasgow Coma Score 352
Neurocritical Care and Management after Traumatic Brain Injury 353
Additional Resources 355
Section 1—Normal and Abnormal Development 355
Section 2—Cerebral Cortex and Neurocognitive Disorders 355
Section 3—Epilepsy 355
Section 4—Psychiatry 355
Depression/Bipolar Disorder 355
Anxiety/Panic/PTSD Disorders 355
Obsessive-Compulsive Disorder 355
Somatoform/Conversion Disorders 355
Conversion Disorder 355
Schizophrenia 355
Addiction 355
Borderline Personality Disorder 355
Intimate Partner Violence 355
Organic Brain Disorders 355
Child Psychiatry 355
Section 5—Hypothalamus, Pituitary, Sleep, and Thalamus 356
Section 6—Disorders of Consciousness 356
Section 7—Basal Ganglia and Movement Disorders 356
Dystonia 356
Chorea/Ballism 356
Tremor 356
Tics and Tourette Syndrome 356
Myoclonus 356
Wilson Disease 356
Cerebral Palsy 356
Section 8—Cerebellum and Ataxia 356
Section 9—Cerebral Circulation and Stroke 356
Section 10—Multiple Sclerosis and Other Central Nervous System Autoimmune Disorders 357
ADEM, Tumescent MS 357
Neuromyelitis Optica 357
Other Neuroimmunology 357
Stiff-Man Syndrome 357
Section 11—Infections of the Nervous System 357
Section 12—Neuro-Oncology 357
Section 13—Headache 358
Section 14—Head Trauma 358
Index 359
A 359
B 359
C 360
D 361
E 361
F 362
G 362
H 362
I 363
J 363
K 363
L 363
M 363
N 364
O 365
P 365
Q 366
R 366
S 366
T 367
U 367
V 367
W 368
Y 368
Z 368