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Kirklin/Barratt-Boyes Cardiac Surgery E-Book

Kirklin/Barratt-Boyes Cardiac Surgery E-Book

Nicholas T. Kouchoukos | Eugene H. Blackstone | Frank L. Hanley | James K Kirklin

(2012)

Additional Information

Book Details

Abstract

Now in its 4th edition, Kirklin/Barratt-Boyes Cardiac Surgery remains your indispensable source for definitive, state-of-the-art answers on every aspect of adult and pediatric cardiac surgery. This dynamic medical reference thoroughly and systematically covers the full range of new and classic surgical procedures—including the latest alternate and minimally invasive surgical techniques—and presents the up-to-date clinical evidence you need to make effective management decisions.

  • Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, definitive text in the field!
  • Get comprehensive coverage of all areas of cardiac surgery, including ischemic, valvular, and congenital heart disease; cardiac tumors; constrictive pericarditis; thoracic aortic surgery; cardiac transplantation; coronary artery disease; aortic valve disease; cardiac rhythm disturbances; heart failure and transplantation; disease of the thoracic aorta; tetralogy of Fallot; anesthesia; and postoperative care.
  • Stay current with the latest advancements and practices. Comprehensive updates throughout include new information on endovascular management of thoracic aorta disease; new data on clinical outcomes; the most recent minimally invasive procedures; non-invasive CT angiography; new alternative surgical approaches to mitral valve surgery; and many other hot topics!
  • Make the most well-informed decisions and achieve optimal outcomes by exploring each condition's natural history; diagnostic criteria; indications for surgery; operative techniques; and follow-up care.
  • Reference information quickly thanks to a new, streamlined format.

Table of Contents

Section Title Page Action Price
e9781416063919v1.pdf 1
Front cover 1
Expert Consult page 2
Kirklin/Barratt-Boyes Cardiac Surgery 3
Copyright page 6
Contributors 7
Acknowledgments 9
Preface to Fourth Edition 11
Table of Contents 13
I General Considerations 15
1 Anatomy, Dimensions, and Terminology 15
Cardiac Chambers and Major Vessels 16
Right Atrium 16
Left Atrium 16
Right Ventricle 18
Left Ventricle 20
Myoarchitecture of the Ventricles 21
Great Arteries 25
Atrial Septum 25
Ventricular Septum 25
Muscular Septum 25
Membranous Septum 25
Atrioventricular Septum 25
Conduction System 26
Sinus Node 26
Internodal Pathways 26
Atrioventricular Node 26
Bundle of His and Bundle Branches 27
Cardiac Valves 27
Mitral Valve 30
Tricuspid Valve 32
Aortic Valve 33
Pulmonary Valve 33
Coronary Arteries 34
Left Main Coronary Artery 35
Left Anterior Descending Coronary Artery 35
Left Circumflex Coronary Artery 37
Right Coronary Artery 37
Coronary Arterial Supply to Specialized Areas of the Heart 37
Dimensions of Normal Cardiac and Great Artery Pathways 39
Dimensions of the Pathway 39
Normalization of Pathway Dimensions 40
Standardization of Dimensions 40
Dimensions of the Pulmonary Arteries 43
Relating Dimensions to Outcome 43
Dimensions of Normal Ventricles 43
Terminology and Classification of Heart Disease 44
Situs of the Thoracic Viscera and Atria 44
Situs of the Ventricles 45
Completeness of the Ventricles 45
Dominance of the Ventricles 45
Cardiac Connections 45
Cardiac and Arterial Positions 46
Atrioventricular Flow Pathways 46
Defects and Abnormalities 46
Conventional Diagnoses 46
Symbolic Convention of Van Praagh 47
1A Morphogenesis 47
1B Normal Pathway Dimensions from Autopsy Specimens 47
1C Normal Pathway Dimensions from Cineangiography 50
1D Normal Pathway Dimensions from Two-Dimensional Echocardiography 53
1E Comparison of Pathway Dimensions from Different Measurement Modalities 60
Comparisons between Cineangiographic Dimensions and Those Obtained at Autopsy 60
Comparisons between Two-Dimensional Echocardiographic Dimensions and Those Obtained at Autopsy 60
Other Comparisons 60
1F Comparison of Methods for Normalizing the Dimensions of Pulmonary Arteries 62
1G Normal Ventricular Volume, Masses, and Dimensions from Different Measurement Modalities 63
1H Illustrative Models of Congenital Heart Disease 75
References 75
A 75
B 76
C 76
D 76
E 76
F 77
G 77
H 77
J 77
K 77
L 77
M 78
N 78
O 78
P 78
R 78
S 78
T 79
U 79
V 79
W 79
Y 80
Z 80
2 Hypothermia, Circulatory Arrest, and Cardiopulmonary Bypass 81
Section I Hypothermic Circulatory Arrest 82
Historical Note 82
Hypotheses 83
Oxygen Consumption During Hypothermia 83
Relationship between Oxygen Consumption and Body Temperature 83
Total Body Oxygen Consumption after Surface Cooling 84
Oxygen Consumption during Hypothermia in Tissue Slices and Isolated Organs 84
Other Phenomena During Hypothermia and Circulatory Arrest 86
No-Reflow Phenomenon 86
Changes in Plasma Volume 86
Damaging Effects of Circulatory Arrest During Hypothermia 86
Brain Function and Structure: Risk Factors for Damage 86
Temperature and Duration 87
Characteristics of the Cooling Process 87
Cerebral Blood Flow during Cooling and Rewarming 88
Biochemical Milieu 88
Electroencephalogram Before Arrest 89
Patient Age 89
Effects of Brain Damage 90
Evidence of Gross Neurologic Damage 90
Postoperative Intellectual Capacity 91
Spinal Cord Function 92
Renal Function and Structure 92
Experimental Studies 92
Studies in Humans 93
Liver Function 93
Safe Duration of Circulatory Arrest 93
Section II Whole-Body Perfusion during Cardiopulmonary Bypass 94
Historical Note 94
Uniqueness of Cardiopulmonary Bypass 95
Controlled Variables 95
Arterial Output to the Patient 95
Venous Input from the Patient 96
Vacuum-Assisted Venous Return 96
Siphon (Gravity) Drainage 96
Venous Pumping 96
Gas Exchange 96
Arterial Oxygen Levels 97
Arterial Carbon Dioxide Pressure 97
Heparin Levels 98
Perfusate 99
Diluent 99
Hemoglobin Concentration 99
Albumin Concentration 100
Other Additives 100
Changes during Cardiopulmonary Bypass 101
Total Systemic Blood Flow 101
Arterial Pressure Waveform 102
Systemic Venous Pressure 102
Pulmonary Venous Pressure 103
Temperature 103
Response Variables 103
Whole-Body (Nonspecific) Inflammatory Response to Use of a Pump-Oxygenator 103
Humoral Response 104
Cellular Response 104
Metabolic Response 105
Details of the Whole-Body Inflammatory Response 105
Neutrophil Activation 105
Platelet Response 105
Complement Activation 107
Kallikrein-Bradykinin Activation 108
Coagulation Cascade 108
Fibrinolytic Cascade 108
Arachidonic Acid Cascade 109
Cytokines 109
Other Mediators of Inflammation 109
Protein Denaturation 109
Oxygen Consumption 109
Total Body Oxygen Consumption 109
Cerebral Oxygen Consumption 110
Mixed Venous Oxygen Levels 110
Metabolic Acid-Base Status 110
Hemolysis 110
Systemic Vascular Resistance and Arterial Blood Pressure 111
Distribution of Blood Flow 112
Cerebral Blood Flow 112
Cutaneous Blood Flow 112
Venous Tone 113
Catecholamine Response 113
Adrenal Cortical Hormones 113
Vasopressin 113
Body Composition 113
Thermal Balance 113
Agents of Damage 114
Foreign Surfaces 114
Shear Stresses 115
Incorporation of Foreign Substances 115
Heparin 115
Protamine 116
Prevention of Undesirable Responses 116
Safe Duration of Total Cardiopulmonary Bypass 116
Section III Clinical Methodology of Cardiopulmonary Bypass 117
General Comments and Strategy 117
Positioning Monitoring Devices 117
Positioning Patient 117
Preparing Surgical Field 117
Incision 117
Primary Median Sternotomy 117
Alternative Primary Incisions 118
Secondary Median Sternotomy 118
Preparation For Cardiopulmonary Bypass 119
Siting and Purse-String Sutures for Aortic Cannulation 119
Siting and Purse-String Sutures for Venous Cannulation 120
Heparinization and Later Protamine Administration 120
Arterial Cannulation 121
Venous Cannulation 121
Commencing Cardiopulmonary Bypass and Left Heart Venting 122
Cardiopulmonary Bypass During Operation and Rewarming 122
De-Airing The Heart 122
Completing Cardiopulmonary Bypass 123
Positioning Chest Tubes 124
Completing Operation 124
Pump-Oxygenator 124
Components 124
Priming Volume 125
Miniaturized Cardiopulmonary Bypass Circuits 125
Special Situations and Controversies 125
One Versus Two Venous Cannulae 125
Cardiopulmonary Bypass Established by Peripheral Cannulation 126
Femoral Cannulation 126
Axillary Artery Cannulation 126
Other Sites 126
Indications 126
Blood Conservation 126
Left Superior Vena Cava 127
Other Systemic Venous Anomalies 127
Left Atrial Pressure Monitoring 127
Alternative Primary Incisions 127
Minimal Sternotomy and Thoracotomy 127
Right Anterolateral Thoracotomy 129
Left Thoracotomy 129
Port Access 129
Section IV Clinical Methodology of Hypothermic Circulatory Arrest and Its Alternatives 129
General Comments and Strategy 129
Adults 129
Neonates, Infants, and Children 130
Technique in Adults 130
Technique in Neonates, Infants, and Children 130
Hypothermic Circulatory Arrest 130
Preparation for Cardiopulmonary Bypass 130
Cannulation 130
Cardiopulmonary Bypass for Cooling 131
Circulatory Arrest 131
Cardiac Operation 131
Rewarming 131
Continuous Antegrade Cerebral Perfusion 131
Preparation for Cardiopulmonary Bypass 131
Cannulation 131
Cardiopulmonary Bypass and Cooling 132
Preparation for Cerebral Perfusion 132
Arch Reconstruction 132
Reestablishing Total Body Perfusion and Associated Intracardiac Repairs 133
Rewarming 133
2A Equations 133
References 134
A 134
B 134
C 136
D 136
E 137
F 137
G 138
H 139
I 140
J 140
K 140
L 141
M 141
N 142
O 142
P 142
Q 143
R 143
S 143
T 144
U 145
V 145
W 146
Y 146
Z 146
3 Myocardial Management during Cardiac Surgery with Cardiopulmonary Bypass 147
Historical Note 148
Need for Special Measures of Myocardial Management 149
Conditions during Cardiopulmonary Bypass 149
Vulnerability of the Diseased Heart 150
Surgical Requirements 150
Damage from Global Myocardial Ischemia 150
Myocardial Cell Stunning 151
Myocardial Cell Necrosis 151
Endothelial Cell Damage 152
Specialized Conduction Cell Damage 153
Damage from Reperfusion 153
Myocardial Cell Damage 153
Endothelial Cell Damage 154
Specialized Conduction Cell Damage 154
Advantageous Conditions During Ischemia 154
Advantageous Conditions During Reperfusion 155
Blood 156
Leukocyte Depletion 156
Substrate 156
Hydrogen Ion Concentration 156
Calcium 156
Potassium 156
Pressure 156
Flow and Resistance 157
Temperature 157
Suppression of Formation of Oxygen-Derived Free Radicals and Enhancement of Free Radical Scavengers 157
Duration 157
Adenosine 157
Ischemic Postconditioning 158
Methods of Myocardial Management During Cardiac Surgery 158
Continuous Normokalemic Coronary Perfusion 158
Empty Beating Heart 158
Perfusion of Individual Coronary Arteries 158
Hypothermic Fibrillating Heart 159
Moderately Hypothermic Intermittent Global Myocardial Ischemia 159
Profoundly Hypothermic Global Myocardial Ischemia 159
Drug-Mediated Myocardial Protection 159
Cold Cardioplegia (Multidose) 160
Cardioplegic Solution 160
Technique of Antegrade Infusion 160
Technique of Retrograde Infusion 162
Results of Cold Cardioplegia 162
Single-Dose Cold Cardioplegia in Neonates and Infants 162
Continuous Cardioplegia 163
Cold Perfusion 163
Warm Perfusion 163
Cold Cardioplegia, Controlled Aortic Root Reperfusion, and (When Needed) Warm Cardioplegic Induction 163
Circuitry 163
Technique for Elective Surgery 163
Technique for Energy-Depleted Hearts 164
Ancillary Measures for Preventing Myocardial Damage 164
Special Situations and Controversies 164
Species and Model Differences 164
Neonates and Infants 164
Ischemic Damage 165
Reperfusion Damage 165
Abnormal Immature Hearts 165
Methods of Myocardial Management 165
Aortic Valve Surgery 166
Coexisting Mild Aortic Regurgitation 167
Acute Occlusion of the Left Anterior Descending Coronary Artery 167
Large Noncoronary Collateral Flow 167
Active Rheumatic Pericarditis Necessitating Multiple Valve Surgery 168
Reoperative Surgery 168
References 168
A 168
B 168
C 170
D 170
E 170
F 170
G 171
H 171
I 171
J 171
K 172
L 172
M 173
N 173
O 173
P 174
Q 174
R 174
S 175
T 175
V 175
W 176
Y 176
Z 176
4 Anesthesia for Cardiovascular Surgery 177
Section I Anesthetic Consultation for Adult Cardiovascular Surgery 178
Preoperative Preparation and Evaluation 178
Management of Preoperative Medications 178
Cardiovascular Medications 178
Statins 178
Medications Affecting Hemostasis 178
Aspirin 178
Clopidogrel 179
Combination Antiplatelet Therapy 179
Glycoprotein IIb/IIIa Inhibitors 179
Herbal Supplements 180
Monitoring 180
Cannulae 180
Transesophageal Echocardiography 181
Epiaortic Scanning 183
Cerebral Oximetry 183
Medications 183
Premedication 183
Induction Agents 183
Maintenance of Anesthesia 183
Opioids 184
Antifibrinolytic Drugs 184
Heparin Management 184
Monitoring 184
Heparin Resistance 184
Heparin-Induced Thrombocytopenia 185
Heparin Reversal 185
Weaning From Cardiopulmonary Bypass 185
Inotropic and Vasopressor Support 185
Specific Management Issues 186
Fast-Track Anesthesia 186
Perioperative Glucose Control 186
Blood Management 186
Reoperation 187
Off-Pump Coronary Artery Bypass Grafting 187
Heart Transplantation 187
Lung Transplantation 188
Descending Thoracic Artery Aneurysm 188
Transcatheter Aortic Valve Replacement 189
Ventricular Assist Devices 189
Conclusion 189
Section II Anesthesia for Neonates and Children 189
Infants and Children Undergoing Cardiopulmonary Bypass (open Procedures) 189
Laboratory Evaluation 190
Premedication 190
Physiologic Monitoring 190
Temperature 190
Intraoperative Echocardiography 190
Neurologic Monitoring 190
Near-Infrared Spectroscopy 191
Validation of NIRS 191
Clinical Applications 191
Outcomes after Heart Surgery and NIRS Monitoring 191
Anesthetic Agents 192
Intubation and Ventilation 192
Maintenance of Anesthesia 193
Infants and Children Undergoing Hypothermia With or Without Circulatory Arrest 193
Cardiopulmonary Bypass 193
Separation from Cardiopulmonary Bypass 193
Rationale for Specific Therapies 194
Right Ventricular (Pulmonary Ventricle) Dysfunction 194
Left Ventricular (Systemic Ventricle) Dysfunction 194
Management of Hypoplastic Left Heart Physiology 194
Rationale for Managing Fontan, Hemi-Fontan, and Bidirectional Glenn Procedures 195
Infants and Children Not Undergoing Cardiopulmonary Bypass (closed Procedures) 195
Palliative Procedures 195
Closure of Patent Ductus Arteriosus 195
Coarctation of the Aorta 195
One-Lung Ventilation in Children 196
Controversies in Pediatric Anesthesia 196
Effects of Anesthetic Medications on the Developing Brain 196
Blood Glucose Management in the Perioperative Period 196
4A Intraoperative Insulin Management Protocol (Cleveland Clinic) 197
References 198
A 198
B 198
C 198
D 199
E 199
F 199
G 199
H 199
I 200
J 200
K 200
L 200
M 200
O 201
P 201
Q 201
R 201
S 201
T 202
V 202
W 202
Y 202
5 Postoperative Care 203
Section I Subsystems during Early Convalescence after Cardiac Surgery 205
Cardiovascular Subsystem 205
Cardiac Reserve 205
Adequacy 205
Cardiac Index 205
Arterial Blood Pressure 206
Pedal Pulses 206
Skin Temperature 206
Whole Body Oxygen Consumption 207
Mixed Venous Oxygen Level 207
Urine Flow and Serum Potassium 207
Metabolic Acidosis 208
Cardiac Output and Its Determinants 209
Ventricular Preload 209
Ventricular Afterload 209
Myocardial Contractility 210
Relative Performance of Left and Right Ventricles 211
Heart Rate 211
Cardiac Rhythm 211
Causes of Acute Dysfunction (Low Cardiac Output) after Cardiac Surgery 212
Inadequate Operation 212
Myocardial Dysfunction 212
Reduced Preload 212
Hypovolemia. 212
Diastolic Dysfunction. 212
Acute Cardiac Tamponade. 212
Increased Ventricular Afterload 212
Risk Factors for Low Cardiac Output 213
Patient-Specific 213
Procedural 213
Course of Low Cardiac Output 213
Treatment of Low Cardiac Output 214
Noninvasive Methods 214
Intraaortic Balloon Pump 215
Temporary Ventricular Assistance 216
Temporary Ventricular Assist Devices. 216
Management. 217
Results. 217
Indications. 217
Cardiopulmonary Support and Extracorporeal Membrane Oxygenation 217
Management. 218
Results. 218
Indications. 218
Cardiac Arrhythmias 218
Ventricular Electrical Instability 218
Atrial Arrhythmias 219
Prevalence and Risk Factors for Atrial Fibrillation. 219
Prevention of Atrial Fibrillation. 219
Treatment of Atrial Fibrillation. 219
Atrial Flutter. 220
Paroxysmal Atrial Tachycardia. 220
Pulmonary Subsystem 220
Adequacy 220
During Intubation 220
Extubation 221
Causes of Dysfunction 221
Risk Factors for Acute Dysfunction 222
Patient-Specific 222
Procedural 223
Postoperative 223
Course of Dysfunction after Cardiac Surgery 223
Management and Treatment 224
General Measures 224
Prolonged Intubation 224
Reintubation 225
Pulmonary Hypertensive Crises 225
Description. 225
Incremental Risk Factors. 225
Prevention. 226
Renal Subsystem 226
Adequacy 226
Causes of Acute Dysfunction after Cardiac Surgery 227
Risk Factors for Acute Dysfunction 227
Patient-Specific 227
Procedural 227
Postoperative 228
Course of Dysfunction 228
Management and Treatment 228
Neuropsychological Subsystem 229
Generalized (Diffuse) Neuropsychological Function 229
Adequacy 229
Causes of Dysfunction 229
Risk Factors for Acute Dysfunction 229
e9781416063919v2 1251
Front cover 1251
Expert Consult page 1252
Cardiac Surgery 1255
Copyright page 1256
Contributors 1257
Acknowledgments 1259
Preface to Fourth Edition 1261
Table of Contents 1263
VII Congenital Heart Disease 1265
30 Atrial Septal Defect and Partial Anomalous Pulmonary Venous Connection 1265
Definition 1266
Historical Note 1266
Morphology 1266
Types of Atrial Septal Defect 1266
Fossa Ovalis Defect 1266
Posterior Defect 1267
Sinus Venosus Defect 1267
Coronary Sinus Defect 1267
Confluent Defect 1267
Ostium Primum Defect 1267
Types of Partial Anomalous Pulmonary Venous Connection 1267
Sinus Venosus Malformation 1267
Right Superior Pulmonary Vein to Superior Vena Cava 1271
Right Pulmonary Veins to Right Atrium 1271
Right Pulmonary Veins to Inferior Vena Cava (Scimitar Syndrome) 1271
Rare Connections of Right Pulmonary Veins 1271
Left Pulmonary Venous Connections 1271
Bilateral Partial Pulmonary Venous Connection 1271
Cardiac Chambers in Atrial Septal Defect and Related Conditions 1271
Mitral Valve and Atrial Septal Defects 1272
Mitral Prolapse 1272
Mitral Regurgitation 1272
Cleft Mitral Leaflets 1272
Lungs and Pulmonary Vasculature 1272
Associated Cardiac Conditions 1272
Related Conditions 1272
Clinical Features and Diagnostic Criteria 1273
Determinants of Interatrial Shunting 1273
Symptoms 1273
Signs 1273
Chest Radiography 1273
Electrocardiography 1273
Echocardiography 1274
Magnetic Resonance Imaging 1274
Cardiac Catheterization and Cineangiography 1274
Natural History 1276
Survival 1276
Pulmonary Hypertension 1277
Functional Status 1277
Spontaneous Closure 1277
Changes in Pulmonary/Systemic Blood Flow Over Time 1278
Right Ventricular Function 1278
Left Ventricular Function 1278
Atrioventricular Valvar Dysfunction 1278
Supraventricular Arrhythmias 1278
Systemic Arterial Hypertension 1279
Technique of Operation 1279
Fossa Ovalis Atrial Septal Defect 1279
Posterior Atrial Septal Defect 1281
Coronary Sinus Atrial Septal Defect 1281
Sinus Venosus Atrial Septal Defect 1281
Anomalous Connection of Right Pulmonary Veins to Right Atrium 1282
Anomalous Connection of Right Pulmonary Veins to Inferior Vena Cava (Scimitar Syndrome) 1282
Anomalous Connection of Left Pulmonary Veins to Brachiocephalic Vein 1287
Other Anomalous Pulmonary Venous Connections 1287
Treatment of Associated Mitral or Tricuspid Valve Disease 1287
Special Features of Postoperative Care 1287
Results 1288
Early (Hospital) Death 1288
Time-Related Survival 1288
Modes of Death 1289
Incremental Risk Factors for Death 1289
Pulmonary Vascular Disease 1290
Older Age at Operation 1290
Anatomic Type of Interatrial Communication 1290
Functional Status 1290
Hemodynamic Results 1290
Ventricular Function 1290
Arrhythmic Events 1291
Thromboembolism 1292
Reintervention 1292
Indications for Operation 1292
Special Situations and Controversies 1292
Closure of Atrial Septal Defects by Percutaneous Techniques 1292
Direct Suture versus Patch Repair 1293
Patch Material in Atrial Septum 1293
Complications after Repair of Sinus Venosus Malformation 1293
Pulmonary Venous Obstruction after Repair of Scimitar Syndrome 1294
Repair in Presence of Increased Pulmonary Vascular Resistance 1294
References 1294
A 1294
B 1294
C 1294
D 1294
E 1295
F 1295
G 1295
H 1295
J 1295
K 1295
L 1295
M 1296
N 1296
P 1296
R 1296
S 1296
T 1297
V 1297
W 1297
Y 1297
Z 1297
31 Total Anomalous Pulmonary Venous Connection 1298
Definition 1298
Historical Note 1298
Morphology 1299
Pulmonary Venous Anatomy 1299
Cardiac Chamber and Septal Anatomy 1299
Pulmonary Vasculature 1301
Associated Conditions 1301
Clinical Features And Diagnostic Criteria 1301
Presentation 1301
Examination 1301
Chest Radiography 1302
Echocardiography 1302
Cardiac Catheterization and Cineangiography 1302
Magnetic Resonance Imaging and Computed Tomography 1303
Physiology of Common Mixing Chamber 1303
Natural History 1304
Technique Of Operation 1304
Total Anomalous Pulmonary Venous Connection to Left Brachiocephalic Vein 1305
Total Anomalous Pulmonary Venous Connection to Superior Vena Cava 1305
Total Anomalous Pulmonary Venous Connection to Coronary Sinus 1310
Total Anomalous Pulmonary Venous Connection to Right Atrium 1313
Total Anomalous Pulmonary Venous Connection to Infradiaphragmatic Vein 1313
Miscellaneous Types of Total Anomalous Pulmonary Venous Connection 1313
Mixed Total Anomalous Pulmonary Venous Connection 1313
Special Features Of Postoperative Care 1313
Results 1316
Survival 1316
Early (Hospital) Death 1316
Time-Related Survival 1316
Modes of Death 1316
Incremental Risk Factors for Death 1316
Functional Status 1317
Hemodynamic Result 1317
Cardiac Rhythm 1317
Reoperation and Development of Postoperative Pulmonary Venous Obstruction 1317
Anastomotic Stenosis 1318
Pulmonary Vein Stenosis 1318
Indications For Operation 1319
Special Situations And Controversies 1319
Pulmonary Vein Stenosis 1319
Delayed Operation 1319
Operative Exposure 1319
Surgical Enlargement of Left Atrium 1320
References 1320
A 1320
B 1320
C 1320
D 1321
E 1321
F 1321
G 1321
H 1321
I 1321
J 1321
K 1322
L 1322
M 1322
N 1322
O 1322
P 1322
R 1322
S 1323
T 1323
U 1323
V 1323
W 1323
Y 1323
32 Cor Triatriatum 1324
Definition 1324
Historical Note 1324
Morphology 1324
Morphology of Classic Cor Triatriatum 1324
Relationship of Cor Triatriatum to Partial and Total Anomalous Pulmonary Venous Connection 1324
Relationship of Cor Triatriatum to a Left Superior Vena Cava 1327
Associated Anomalies 1327
Clinical Features and Diagnostic Criteria 1327
Natural History 1327
Technique Of Operation 1327
Classic Cor Triatriatum 1327
Atypical Cor Triatriatum 1328
Special Features Of Postoperative Care 1329
Results 1329
Early (Hospital) Death 1329
Time-Related Survival and Functional Status 1329
Indications For Operation 1330
References 1331
A 1331
B 1331
C 1331
G 1331
H 1331
J 1331
K 1331
L 1331
M 1331
N 1331
O 1331
P 1331
R 1331
S 1331
T 1331
V 1331
W 1332
33 Unroofed Coronary Sinus Syndrome 1333
Definition 1333
Historical Note 1333
Morphology 1333
Completely Unroofed Coronary Sinus with Persistent Left Superior Vena Cava 1333
Completely Unroofed Coronary Sinus without Persistent Left Superior Vena Cava 1334
Partially Unroofed Midportion of Coronary Sinus 1334
Partially Unroofed Terminal Portion of Coronary Sinus 1334
Relationship of Unroofed Coronary Sinus Syndrome to Cor Triatriatum and Atrioventricular Septal Defect 1334
Atrial Isomerism 1334
Clinical Features And Diagnostic Criteria 1334
Natural History 1335
Technique Of Operation 1335
Isolated Completely Unroofed Coronary Sinus with Persistent Left Superior Vena Cava 1335
Intracardiac Repair 1335
Extracardiac Repair 1335
Partially Unroofed Midportion of Coronary Sinus 1337
Partially Unroofed Terminal Portion of Coronary Sinus 1337
Unroofed Coronary Sinus Syndrome with Left Superior Vena Cava and Atrioventricular Septal Defect 1337
Completely Unroofed Coronary Sinus Associated with Other Complex Cardiac Anomalies 1337
Results 1337
Early (Hospital) Death 1337
Time-Related Survival and Functional Status 1339
Indications For Operation 1339
Special Situations And Controversies 1340
Ligation of Left Superior Vena Cava 1340
References 1341
A 1341
C 1341
D 1341
F 1342
H 1342
K 1342
L 1342
M 1342
O 1342
Q 1342
R 1342
S 1342
T 1342
V 1342
W 1342
34 Atrioventricular Septal Defect 1343
Definition 1344
Historical Note 1344
Morphology 1344
Surgical Treatment 1344
Morphology 1345
General Morphologic Characteristics 1345
Atrial Septal Deficiency and Interatrial Communications 1349
Partial Atrioventricular Septal Defect 1349
Common Atrium 1349
Absence of Interatrial Communication 1349
Ventricular Septal Deficiency and Interventricular Communications 1350
Partial Atrioventricular Septal Defect 1350
Complete Atrioventricular Septal Defect 1350
Atrioventricular Valves 1350
Two Atrioventricular Valve Orifices 1350
Common Atrioventricular Orifice 1352
Unusual Atrioventricular Combinations 1354
Accessory Orifice 1354
Single Papillary Muscle 1355
Ventricles 1355
Septal Malalignment 1355
Left Ventricular Outflow or Inflow Obstruction 1356
Conduction System 1356
Major Associated Cardiac Anomalies 1356
Patent Ductus Arteriosus 1356
Tetralogy of Fallot 1356
Double Outlet Right Ventricle 1356
Transposition of the Great Arteries 1357
Completely Unroofed Coronary Sinus with Left Superior Vena Cava 1357
Minor Associated Cardiac Anomalies 1357
Pulmonary Vascular Disease 1357
Down Syndrome 1357
Inlet Septal Type of Ventricular Septal Defect 1357
Clinical Features and Diagnostic Criteria 1357
Pathophysiology 1357
Atrioventricular Valve Regurgitation 1358
Symptoms and Physical Findings 1358
Chest Radiograph 1358
Electrocardiogram 1358
Two-Dimensional Echocardiogram 1358
Cardiac Catheterization and Cineangiogram 1360
Special Situations and Associated Defects 1360
Natural History 1360
Technique of Operation 1366
Repair of Complete Atrioventricular Septal Defect with Little or No Bridging of Left Superior and Left Inferior Leaflets: Rastelli Type A 1367
Two-Patch Technique 1367
Repair of Complete Atrioventricular Septal Defect with Bridging of Left Superior Leaflet: Rastelli Type B or C 1371
Repair of Complete Atrioventricular Septal Defect with Single-Patch Technique 1371
Repair of Complete Atrioventricular Septal Defect with Modified Single-Patch Technique 1373
Repair of Partial Atrioventricular Septal Defect with Little or No Left Atrioventricular Valve Regurgitation 1373
Repair of Atrioventricular Septal Defect with Small Interchordal Interventricular Communications (Intermediate Form) 1374
Repair of Atrioventricular Septal Defect with Common Atrium 1374
Repair of Complete or Partial Atrioventricular Septal Defect with Moderate or Severe Left Atrioventricular Valve Regurgitation 1374
Right Atrioventricular Valve 1377
Left Superior Leaflet–Right Superior Leaflet and Left Inferior Leaflet–Right Inferior Leaflet Commissures 1377
Replacement of Left Atrioventricular Valve 1377
Repair of Complete Atrioventricular Septal Defect with Tetralogy of Fallot 1378
Repair of Complete Atrioventricular Septal Defect with Double Outlet Right Ventricle 1379
Repair with Transposition of the Great Arteries 1379
Special Features of Postoperative Care 1379
Results 1379
Survival 1379
Early (Hospital) Death 1379
Time-Related Survival 1380
Incremental Risk Factors for Premature Death 1380
Earlier Date of Operation 1380
Higher New York Heart Association Functional Class 1380
Important Pre-Repair Atrioventricular Valve Regurgitation 1380
Interventricular Communication 1380
Accessory Valve Orifice 1381
Major Associated Cardiac Anomalies 1381
Young Age 1381
Down Syndrome 1381
Need for Reoperation 1381
Other Risk Factors 1381
Heart Block and Other Arrhythmias 1381
Functional Status 1381
Atrioventricular Valve Function 1381
Left Ventricular Outflow Tract Obstruction 1382
Residual Pulmonary Hypertension 1382
Indications for Operation 1382
Partial Atrioventricular Septal Defects 1382
Complete Atrioventricular Septal Defects 1383
Coexisting Cardiac Anomalies 1383
Special Situations and Controversies 1383
Pulmonary Trunk Banding 1383
Septal Patches 1383
Avoiding Heart Block 1383
Unbalanced Atrioventricular Septal Defects 1383
Late Reoperation 1384
References 1384
A 1384
B 1385
C 1385
D 1386
E 1386
F 1386
G 1386
H 1386
I 1386
J 1386
K 1386
L 1387
M 1387
N 1387
O 1388
P 1388
Q 1388
R 1388
S 1388
T 1389
U 1389
V 1389
W 1389
Y 1389
35 Ventricular Septal Defect 1390
Section I Primary Ventricular Septal Defect 1391
Definition 1391
Historical Note 1391
Morphology 1391
Size 1391
Location in Septum and Relationship to Conduction System 1392
Perimembranous Ventricular Septal Defect 1393
Ventricular Septal Defect in Right Ventricular Outlet (Doubly Committed Subarterial Ventricular Septal Defect) 1394
Inlet Septal Ventricular Septal Defect 1395
Muscular Ventricular Septal Defect 1397
Confluent Ventricular Septal Defect 1399
Ventricular Septal Defect with Straddling or Overriding Tricuspid Valve 1399
Associated Lesions 1399
Pulmonary Vascular Disease 1401
Clinical Features And Diagnostic Criteria 1402
Clinical Findings 1402
Two-Dimensional Echocardiography 1403
Other Noninvasive Diagnostic Methods 1403
Cardiac Catheterization 1403
Angiography 1404
Natural History 1404
Spontaneous Closure 1404
Pulmonary Vascular Disease 1409
Infective Endocarditis 1409
Premature Death 1409
Clinical Course 1410
Development of Aortic Regurgitation 1410
Development of Infundibular Pulmonary Stenosis 1410
Technique Of Operation 1410
Repair of Perimembranous Ventricular Septal Defect 1410
Repair of Doubly Committed Subarterial Ventricular Septal Defect 1412
Repair of Inlet Septal Ventricular Septal Defect 1412
Repair of Muscular Ventricular Septal Defect 1412
Closure of Associated Patent Ductus Arteriosus 1416
Pulmonary Trunk Banding 1416
Pulmonary Trunk Debanding 1416
Special Features Of Postoperative Care 1417
Results 1417
Early (Hospital) Death 1417
Mode of Early Death 1417
Incremental Risk Factors for Hospital Death 1417
Survival 1418
Physical Development 1418
Conduction Disturbances 1418
Right Bundle Branch Block 1418
Right Bundle Branch Block and Left Anterior Hemiblock 1418
Ventricular Arrhythmias 1419
Permanent Heart Block 1419
Cardiac Function 1419
Residual Shunting 1419
Pulmonary Hyperinflation Syndrome 1420
Surgically Produced Aortic or Tricuspid Regurgitation 1420
Pulmonary Hypertension 1420
Surgical Cure 1421
Indications For Operation 1421
Special Situations And Controversies 1422
Ventricular Septal Defect and Patent Ductus Arteriosus 1422
Ventricular Septal Defect and Coarctation of Aorta 1422
Pulmonary Trunk Banding 1423
Right Atrial versus Right Ventricular Approach for Perimembranous Ventricular Septal Defect 1424
Closure of Ventricular Septal Defect Through Less Invasive Approaches 1424
Percutaneous Closure of Ventricular Septal Defects 1424
Closure of Ventricular Septal Defect When Pulmonary Resistance Is High 1424
Section II Ventricular Septal Defect and Aortic Regurgitation 1424
Definition 1424
Historical Note 1424
Morphology And Morphogenesis 1425
Mechanism of Aortic Regurgitation 1425
Clinical Features And Diagnostic Criteria 1426
Natural History 1426
Technique Of Operation 1426
Results 1429
Survival 1429
Heart Block 1429
Relief of Aortic Regurgitation 1429
Freedom from Aortic Valve Replacement 1429
Indications For Operation 1430
Special Situations And Controversies 1430
Section III Straddling and Overriding Tricuspid (or Mitral) Valve 1430
Definition 1430
Historical Note 1430
Morphology 1431
Morphologic Syndromes 1431
Conduction System 1431
Clinical Features And Diagnostic Criteria 1431
Technique Of Operation 1432
Section of Straddling Cords 1432
Slotting of Repair Patch 1432
Reattachment of Sectioned Tensor Apparatus 1432
Minor Septation 1432
Replacement of Straddling Atrioventricular Valve 1432
Fontan Operation 1433
Cardiac Transplantation 1434
Results 1434
Indications For Operation 1435
References 1435
A 1435
B 1435
C 1436
D 1436
E 1436
F 1436
G 1437
H 1437
J 1437
K 1437
L 1438
M 1438
N 1439
O 1439
P 1439
Q 1439
R 1439
S 1440
T 1440
U 1441
V 1441
W 1441
Y 1441
Z 1441
36 Congenital Sinus of Valsalva Aneurysm and Aortico–Left Ventricular Tunnel 1442
Section I Unruptured and Ruptured Sinus of Valsalva Aneurysms 1442
Definition 1442
Historical Note 1442
Morphology 1443
Rupture 1443
Associated Cardiac Anomalies 1446
Ventricular Septal Defect 1446
Aortic Valve Abnormalities and Aortic Regurgitation 1446
Pulmonary Stenosis 1447
Other Anomalies 1447
Clinical Features And Diagnostic Criteria 1447
Natural History 1448
Technique Of Operation 1448
Ruptured Right Sinus of Valsalva Aneurysm, with Ventricular Septal Defect 1448
Ruptured Sinus of Valsalva Aneurysm into Right Atrium, without Ventricular Septal Defect 1451
Unruptured Sinus of Valsalva Aneurysm 1451
Special Features Of Postoperative Care 1451
Results 1451
Survival 1451
Risk Factors for Premature Late Death 1451
Functional Status 1452
Complications 1452
Indications For Operation 1452
Special Situations And Controversies 1453
Transcatheter Closure of Ruptured Sinus of Valsalva Aneurysm 1453
Section II Aortico–Left Ventricular Tunnel 1453
Definition 1453
Historical Note 1453
Morphology 1453
Clinical Features And Diagnostic Criteria 1453
Natural History 1453
Technique Of Operation 1453
Special Features Of Postoperative Care 1454
Results 1454
Indications For Operation 1454
References 1454
A 1454
B 1454
C 1455
D 1455
E 1455
F 1455
G 1455
H 1455
J 1455
K 1455
L 1456
M 1456
N 1456
O 1456
P 1456
R 1456
S 1456
T 1456
V 1457
W 1457
37 Patent Ductus Arteriosus 1458
Definition 1458
Historical Note 1458
Morphology and Morphogenesis 1459
Morphology of Normal Ductal Closure 1459
Position and Absence 1459
Anatomic Details 1459
Isolated Patent Ductus Arteriosus 1459
Patent Ductus Arteriosus as a Coexisting Anomaly 1459
Histology 1461
Aneurysms of Ductus Arteriosus 1461
Clinical Features and Diagnostic Criteria 1461
Large Patent Ductus Arteriosus 1461
Moderate-Sized Patent Ductus Arteriosus 1461
Small Patent Ductus Arteriosus 1462
Special Investigations 1462
Natural History 1462
Spontaneous Closure 1462
Pulmonary Vascular Disease 1462
Rupture 1462
Death 1462
Modes of Death 1463
Technique of Operation 1463
Closure of Patent Ductus Arteriosus 1463
Posterolateral Thoracotomy 1463
Division 1463
Ligation 1466
Transaxillary Muscle-Sparing Lateral Thoracotomy 1466
Closure of Patent Ductus Arteriosus in Association with Repair of Intracardiac Lesions 1466
Closure of Patent Ductus Arteriosus in Older Adults 1466
Closure of Patent Ductus Arteriosus in Premature Infants 1468
Special Features of Postoperative Care 1468
Results 1468
Early (Hospital) Death 1468
Incremental Risk Factors for Early Death 1468
Time-Related Survival 1469
Symptomatic and Functional Status 1469
Physical Development 1469
Recurrence of Ductal Patency 1469
False Aneurysm 1469
Left Vocal Cord Paralysis 1469
Phrenic Nerve Paralysis 1469
Chylothorax 1469
Indications for Operation 1469
Special Situations and Controversies 1470
Patent Ductus Arteriosus in Preterm Infants 1470
Historical Note 1470
Clinical Features and Diagnostic Criteria 1470
Natural History 1470
Technique of Operation 1470
Special Features of Postoperative Care 1470
Early Results 1470
Late Results 1470
Indications for Operation 1470
Percutaneous (Catheter) Closure of Patent Ductus Arteriosus 1471
Thoracoscopic Closure of Patent Ductus Arteriosus 1471
References 1471
A 1471
B 1471
C 1471
D 1472
E 1472
F 1472
G 1472
H 1472
J 1473
K 1473
L 1473
M 1473
N 1473
O 1473
P 1473
R 1474
S 1474
T 1474
U 1474
V 1474
W 1474
Z 1474
38 Ventricular Septal Defect with Pulmonary Stenosis or Atresia 1475
Section I Tetralogy of Fallot with Pulmonary Stenosis 1478
Definition 1478
Historical Note 1478
Morphology 1478
Developmental Considerations 1478
Right Ventricular Outflow Tract 1479
Infundibulum 1479
Pulmonary Valve 1479
Right Ventricular–Pulmonary Trunk Junction 1482
Pulmonary Trunk 1482
Pulmonary Trunk Bifurcation 1482
Right and Left Pulmonary Arteries 1482
Distal Pulmonary Arteries and Veins 1483
Dimensions of Right Ventricular Outflow Tract and Pulmonary Arteries 1483
Convenient Morphologic Categories of Right Ventricular Outflow Obstruction 1484
Iatrogenic Pulmonary Arterial Problems 1484
Collateral Pulmonary Arterial Blood Flow 1485
Ventricular Septal Defect 1485
Conduction System 1488
Aorta 1488
Aortic Arch and Ductus Arteriosus 1488
Right Ventricle 1489
Left Ventricle 1489
Coronary Arteries 1490
Major Associated Cardiac Anomalies 1490
Minor Associated Cardiac Anomalies 1490
Clinical Features and Diagnostic Criteria 1490
Clinical Presentation 1490
Physical Examination 1490
Laboratory Studies 1491
Chest Radiography 1491
Electrocardiography 1491
Echocardiography 1491
Cardiac Catheterization and Angiography 1492
Computed Tomography 1493
Magnetic Resonance Imaging 1494
Natural History 1494
Symptoms and Survival 1495
Pulmonary Artery Thromboses 1495
Pulmonary Vascular Disease 1497
Genetic History 1497
Technique of Operation 1497
General Plan and Details of Repair Common to All Approaches 1497
Surgical Evaluation 1497
Conceptual Approach to Surgery 1497
Approach 1497
Transanular Patch 1497
Right Coronary Artery Branches 1498
Anomalous Left Anterior Descending Coronary Artery 1498
Pulmonary Valve 1498
Atrial Septal Communications 1498
Tricuspid Valve 1498
Right Ventricular Muscle Bundles 1498
Preparations for Cardiopulmonary Bypass 1499
Technical Details of Repair 1499
Infundibular Dissection 1499
Pulmonary Valvotomy 1502
VSD Closure 1503
Decision and Technique for Transanular Patching 1504
Assessing Postrepair Right Ventricular Outflow Tract Obstruction 1506
Measuring Postrepair (Operating Room [OR]) PRV/LV 1506
Measuring Postrepair (OR) Right Ventricular Outflow Tract Pressure Gradient 1508
Management of Atrial Septum 1508
Repair of Uncomplicated Tetralogy of Fallot with Pulmonary Stenosis via Right Ventricle 1508
Repair of Uncomplicated Tetralogy of Fallot with Pulmonary Stenosis via Right Atrium 1509
Repair of Tetralogy of Fallot in Infancy 1510
Repair of Tetralogy of Fallot with Stenosis at Origin of Left Pulmonary Artery 1510
Repair of Tetralogy of Fallot with Stenosis at Origin of Right Pulmonary Artery 1510
Repair of Tetralogy of Fallot with Bifurcation Stenosis of Pulmonary Trunk 1511
Repair of Tetralogy of Fallot with Anomalous Origin of Left Anterior Descending Coronary Artery from Right Coronary Artery 1512
Repair of Tetralogy of Fallot after Blalock-Taussig Shunt or Polytetrafluoroethylene Interposition Shunt 1514
Repair of Tetralogy of Fallot after Waterston and Potts Shunts 1515
Technique of Shunting Operations 1515
Classic Right Blalock-Taussig Shunt 1515
Interposition Shunt between Left Subclavian and Left Pulmonary Artery 1518
Right-Sided Interposition Shunt Through Median Sternotomy 1518
Classic Left Blalock-Taussig Shunt (in Patients with Right Aortic Arch) 1518
Right-Sided Interposition Shunt (in Patients with Right Aortic Arch) 1519
Special Features of Postoperative Care 1519
Repair 1519
Systemic–Pulmonary Arterial Shunting 1521
Results 1522
Survival 1522
Early (Hospital) Death 1522
Time-Related Survival and the Question of “Cure” 1522
Modes of Death 1524
Incremental Risk Factors for Death 1524
Young Age at Repair 1524
Older Age at Repair 1525
Severity of Right Ventricle–Pulmonary Trunk Junction Hypoplasia 1525
Small Size of Right and Left Pulmonary Arteries 1525
Transanular Patch 1526
Postrepair PRV/LV 1526
Previous Palliative Operations 1527
Multiple Ventricular Septal Defects 1527
Coexisting Related Cardiac Anomalies 1527
Other Risk Factors 1527
Heart Block 1527
Junctional Ectopic Tachycardia 1528
Functional Status 1528
Right Ventricular Function 1529
Right Ventricular Aneurysms 1530
Residual Right Ventricular Outflow Obstruction 1530
Reoperation and Other Reinterventions for Right Ventricular Outflow Problems 1531
Left Ventricular Function 1532
Pulmonary Function 1533
Recurrent (Residual) Ventricular Septal Defects 1533
Sudden Death and Important Arrhythmic Events 1533
Infective Endocarditis 1533
Interim Results after Classic Shunting Operations 1533
Survival 1533
Interim Events 1534
Indications for Operation 1534
Special Situations and Controversies 1535
Timing and Type of Initial Surgery 1535
Rationale for Use of Postrepair PRV/LV 1535
Initial Palliative Operations 1535
Initial Palliation by β-Adrenergic Blockade 1535
Initial Palliation by Balloon Valvotomy 1536
Monocusp Valves Beneath Transanular Patches 1536
Timing of Pulmonary Valve Replacement for Pulmonary Regurgitation Late after Repair 1536
Percutaneous Pulmonary Valve Implantation 1536
Section II Tetralogy of Fallot with Pulmonary Atresia 1536
Definition 1536
Historical Note 1536
Morphology and Morphogenesis 1537
Tetralogy of Fallot with Congenital Pulmonary Atresia 1537
Right Ventricular Outflow Tract 1537
Pulmonary Trunk 1537
Right and Left Pulmonary Arteries 1537
Confluence of Right and Left Pulmonary Arteries 1537
Stenoses of Origins of Pulmonary Arteries 1538
Distribution (Arborization) of Pulmonary Arteries 1538
Stenoses of Pulmonary Arteries 1539
Size of Pulmonary Arteries 1539
Abnormal Hilar Branching Patterns 1539
Alternative Sources of Pulmonary Blood Flow 1539
Large Aortopulmonary Collateral Arteries 1539
Paramediastinal Collateral Arteries 1541
Bronchial Collateral Arteries 1541
Other Collaterals 1541
Acquired Collaterals 1541
Ductus Arteriosus 1541
Morphogenesis 1541
Tetralogy of Fallot with Acquired Pulmonary Atresia 1541
Clinical Features and Diagnostic Criteria 1542
Echocardiography 1542
Catheterization and Angiography 1543
Computed Tomographic Angiography 1543
Natural History 1543
Natural History of Pathophysiologic Subgroups 1545
Confluent and Normally Distributing Right and Left Pulmonary Arteries and Patent Ductus Arteriosus 1545
Confluent, Nonconfluent, or Absent Right and Left Pulmonary Arteries with Aortopulmonary Collaterals 1545
Pulmonary Arterial Disease 1545
Technique of Operation 1546
Repair of Tetralogy of Fallot with Acquired Pulmonary Atresia 1546
Repair of Tetralogy of Fallot with Pulmonary Atresia and Confluent and Normally Distributing Right and Left Pulmonary Arteries and Patent Ductus Arteriosus 1546
Repair of Tetralogy of Fallot with Pulmonary Atresia and Confluent, Nonconfluent, or Absent Right and Left Pulmonary Arteries and Aortopulmonary Collaterals 1546
One-Stage Unifocalization and Intracardiac Repair 1546
Assessing True Pulmonary Artery System 1547
Identifying and Assessing Collateral System 1547
Managing Sources of Pulmonary Blood Flow on Cardiopulmonary Bypass 1547
Completing Unifocalization 1549
Assessing Adequacy of Unifocalization 1549
Intracardiac Repair 1552
Establishing Right Ventricle–to–Pulmonary Artery Continuity 1553
Completing the Procedure 1555
Assessing Complete Repair 1555
Special Features of Postoperative Care 1555
Results 1557
After Repair 1557
Early (Hospital) Death 1557
Time-Related Survival 1557
Modes of Death 1557
Incremental Risk Factors for Death 1557
Pulmonary Artery Abnormalities 1557
Age (Size) 1558
Postrepair PRV/LV 1558
Duration of Cardiopulmonary Bypass 1558
Heart Block 1558
Functional Status 1558
Pulmonary Artery Pressure and Resistance 1558
Reintervention 1558
After Palliative Operations for Increasing Pulmonary Blood Flow 1559
Effect on Size of Pulmonary Arteries 1559