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Clinical and Electrophysiologic Management of Syncope, An Issue of Cardiac Electrophysiology Clinics, E-Book

Clinical and Electrophysiologic Management of Syncope, An Issue of Cardiac Electrophysiology Clinics, E-Book

Antonio Raviele | Andrea Natale

(2013)

Additional Information

Book Details

Abstract

This issue of Cardiac Electrophysiology Clinics devoted to syncope a disorder that is associated with increased mortality. Internationally recognized experts discuss the many causes of syncope, helping the clinician to distinguish life-threatening etiologies from benign ones.

Table of Contents

Section Title Page Action Price
Front Cover Cover
Clinical and Electrophysiologic Management of Syncope\r i
Copyright\r ii
Contributors iii
Contents vii
Cardiac Electrophysiology Clinics\r xi
Preface\r xiii
Syncope 387
Key points 387
Introduction 387
Definition 387
Transient Loss of Consciousness 388
Is TLOC Characterized by Rapid Onset and Short Duration? 388
Recovery 388
Rule Out Head Trauma and Epilepsy 388
Epidemiology 389
Classification 389
Pathophysiology 390
Low CO 390
Low Peripheral Resistance 390
Summary 391
References 391
Initial Clinical Evaluation 393
Key points 393
Was LOC complete? 393
Did LOC have rapid onset, short duration, and spontaneous recovery? 395
Diagnosis of the cause of transient LOC 395
Clinical findings of nonsyncopal LOC 396
Epilepsy 396
Transient Ischemic Attack 397
Hypoglycemia 397
Psychogenic Pseudosyncope 397
Cataplexy 398
Diagnosis of the cause of syncope 398
Typical Vasovagal Syncope 398
Situational Syncope 398
Syncope Caused by Orthostatic Hypotension 399
Clinical findings that are only suggestive of a cause of syncope 399
Sleep syncope 400
References 400
The Value of Tilt Testing and Autonomic Nervous System Assessment 403
Key points 403
History 403
Impact of tilt testing 403
Negativity toward tilt testing 404
The place of tilt testing today 405
Autonomic nervous system function tests 405
Summary 405
References 405
Value of Ambulatory Electrocardiographic Monitoring in Syncope 407
Key points 407
Introduction 407
Technical aspects, implanting technique, and follow-up of ILR 407
ILRs in the diagnostic evaluation of transient loss of consciousness 409
Unexplained Syncope 409
Difficult Cases of Epilepsy 409
Unexplained Falls 410
Limitations of ILRs 411
References 411
Value of EP Study and Other Cardiac Investigations 413
Key points 413
Introduction 413
Identification of high-risk patients 413
Electrophysiology study 415
Bradyarrhythmia 415
Tachyarrhythmia 419
Summary 420
References 421
How to Differentiate Syncope from Seizure 423
Key points 423
Introduction 423
Epileptic seizures 423
Syncope 424
Convulsive syncope 425
The role of the history 426
Tilt tests for questionable epilepsy 427
Video recording 428
ILR for questionable epilepsy 428
Health services delivery 428
Summary 429
References 429
Risk Stratification of Patients Presenting with Transient Loss of Consciousness 433
Key points 433
Introduction 433
Classification of syncope 434
Reflex Syncope (Also Termed Neurally Mediated Reflex Syncope) 434
Orthostatic Syncope 434
Syncope Caused by Cardiac Arrhythmias 435
Syncope Caused by Structural Cardiac and Cerebrovascular Disease 435
Syncope mimics 435
Diagnostic pathway 435
Risk stratification of patients with suspected syncope 436
Short-term or Immediate Risk 437
Short-term high-risk TLOC/syncope markers 438
Longer-term risk 438
Risk stratification based on cardiac versus noncardiac causes of syncope 440
Summary 441
References 441
Syncope in Children and Adolescents 443
Key points 443
Introduction 443
How is syncope defined? 443
How common is syncope in children? 443
How is syncope classified in children? 444
Autonomic Syncope 444
Neurocardiogenic syncope 444
Dysautonomic syncope 445
Postural orthostatic tachycardia syndrome 445
Breath-holding spells 446
Blood injury phobia 446
Fainting lark 446
Cardiac Syncope 446
Obstructive causes 446
Hypertrophic cardiomyopathy 446
Aortic stenosis 447
Primary pulmonary hypertension 447
Primary myocardial dysfunction 447
Arrhythmias as a cause of syncope 447
Long QT syndrome 447
Brugada syndrome 448
Cathocholaminergic polymorphic ventricular tachycardia 448
Noncardiac Causes of Syncope 448
How is syncope evaluated in children and adolescents? 449
Laboratory Studies 449
Blood tests 449
Electrocardiogram 449
Video-assisted recording 449
Ambulatory ECG monitoring 449
Head-up tilt table testing 449
Echocardiogram 450
Imaging 450
How is syncope managed in children? 450
Education and Reassurance 450
Physical Countermaneuvers 450
Paced Breathing 451
Fluid Therapy 451
Pharmacologic Treatment 451
Pacemaker Therapy 451
Cardioneuroablation 451
Future perspective 451
References 452
Syncope in the Older Person 457
Key points 457
Introduction 457
Epidemiology 457
Pathophysiology 458
Cardiac Causes of Syncope 458
Neurally Mediated Syncope 458
Managing syncope in the older patient: a case-based approach 460
Case Vignette 1: When is a Fall Not a Fall? 460
Discussion 460
Case Vignette 2: The Swoon 461
Discussion 462
Case Vignette 3: Don’t Look Now… 463
Discussion 463
Recapitulation 464
Summary 464
References 464
Syncope as a Warning Symptom of Sudden Cardiac Death in Athletes 469
Key points 469
Introduction 469
Epidemiology and causes of syncope in athletes 470
Neurally mediated syncope 470
Orthostatic hypotension 470
Cardiogenic syncope in the athlete 470
Hypertrophic Cardiomyopathy 470
Arrhythmogenic Right Ventricular Cardiomyopathy 472
Atherosclerotic Coronary Disease 472
Congenital Coronary Artery Anomaly 473
Ion Channel Diseases 473
Clinical work-up of the athlete with syncope 475
First Level Exams 475
Second- and Third-level Examinations 475
Management 476
Summary 476
References 477
Syncope in Hereditary Arrhythmogenic Syndromes 479
Key points 479
Introduction 479
Medical history 480
Family History 480
Circumstances of Syncope 480
Symptoms 480
Physical examination 481
Electrocardiogram 482
Long QT Syndrome 482
Brugada Syndrome 482
Catecholaminergic Polymorphic Ventricular Tachycardia 483
Short QT Syndrome 483
Summary 483
References 483
Syncope and Idiopathic (Paroxysmal) AV Block 487
Key points 487
Diagnosis of idiopathic AV block 487
Differential diagnosis from other types of AV block 488
Epidemiology of syncope due idiopathic AV block 489
Pathophysiological considerations: the purinergic profile and the role of adenosine 491
Clinical perspectives 492
References 492
Syncope in Patients with Organic Heart Disease 495
Key points 495
Introduction 495
Organic heart disease: what it is and what it is not 496
Is organic heart disease common in the syncope patient, and is it reason for concern? 496
Syncope and death: a temporal association 498
How is syncope related to organic heart disease? Mechanisms of syncope in organic heart disease 499
Evaluation and subsequent management of syncope in patients with organic heart disease 500
Clinical Assessment: History and Physical 500
What evaluation is necessary to rule out a cardiac cause for heart disease? 502
Electrophysiology Testing 503
Implantable Loop Recorders 503
Approach to the syncope patient with organic heart disease in whom the evaluation is negative 504
The future of evaluating patients with syncope 505
Summary 505
References 505
Syncope and Driving 511
Key points 511
Introduction 511
Fitness to drive 511
Pathophysiologic features of syncope and driving 512
Prevalence, recurrence, and prognosis 513
Canadian Cardiovascular Society risk of harm formula 513
Commercial driving 513
Ethics behind regulations and guidelines 514
Current guidelines and recommendations 515
Canadian Medical Association Driver’s Guide: Determining the Medical Fitness to Operate a Motor Vehicle 515
American Heart Association and the Heart Rhythm Society: Personal and Public Safety Issues Related to Arrhythmias that May ... 516
Guidelines for the Diagnosis and Management of Syncope (Version 2009): The Task Force for the Diagnosis and Management of S ... 516
Summary 516
References 517
Therapy for Syncope 519
Key points 519
Introduction 519
Reflex syncope 520
General Measures 521
Water Ingestion 521
Physical Counterpressure Maneuvers 521
Tilt Training 521
Drug Therapy 521
Cardiac Pacing 523
Syncope secondary to orthostatic hypotension 524
Cardiac syncope 524
Syncope and bifascicular block 524
References 524
The Role of the Syncope Management Unit 529
Key points 529
General features of the syncope care delivery organization 529
Rationale for a syncope management unit 530
Syncope: the Challenge 530
Syncope: a Common Problem 530
Syncope is Costly 532
Stakeholders 532
Settings 532
Syncope Management in the ED 532
Syncope Management 533
Syncope Management: Outpatient 533
Professional skill mix for the SMU 533
Role of syncope unit 534
Initial Evaluation 534
Cardiac imaging 534
Provocative testing 537
Head-up tilt test 537
Electrocardiographic monitoring 537
Inpatient telemetry 538
Holter monitoring 538
External loop recorders 538
Implantable loop recorders 538
Exclusion of other causes for transient loss of consciousness 538
Summary 539
References 539
Index 543