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Abstract
Rapidly and accurately identify gynecologic tumors and related lesions with the updated Atlas of Gynecologic Surgical Pathology. Complete with hundreds of stunning photographs and now available with online access, this visually dynamic medical reference book provides you with the know-how you need to perform state-of-the-art gynecologic diagnoses, right at your own microscope.
- Consult this title on your favorite e-reader , conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.
- Quickly and effortlessly find the essential information you need with summary tables, charts, and boxes throughout the text.
- Expedite reference with a consistent approach to every entity discussed, including definitions, clinical features, gross features, microscopic features, and differential diagnoses.
- Avoid diagnostic errors with comprehensive coverage of commonly encountered pitfalls.
- Overcome today's toughest diagnostic challenges with guidance from internationally recognized experts in gynecologic pathology.
- Stay completely current on the newest disease entities and updated classification schemes, and take advantage of nearly 1,000 brand-new references.
- Ensure diagnostic accuracy and gain absolute visual clarity with the addition of 100 images.
- Remain at the forefront of the most recently developed diagnostic methods, such as immunohistochemical diagnosis for malignant lesions and differential diagnosis of neoplastic and pseudoneoplastic lesions.
- Access the complete contents online at Expert Consult.
Table of Contents
| Section Title | Page | Action | Price |
|---|---|---|---|
| Front cover | cover | ||
| Atlas of Gynecologic Surgical Pathology | i | ||
| Copyright page | iv | ||
| Table of Contents | v | ||
| Dedication | vi | ||
| Preface to the Third Edition | ix | ||
| References | ix | ||
| Glossary of Abbreviations and Acronyms | x | ||
| 1 Non-neoplastic Lesions and Benign Tumors of the Vulva | 1 | ||
| Viral Infections | 2 | ||
| Human Papillomavirus (HPV) Infection INCLUDING Condyloma Acuminatum | 2 | ||
| Clinical and gross features (Fig. 1.1) | 2 | ||
| Histological features (Figs. 1.2–1.4) | 2 | ||
| Differential diagnosis | 3 | ||
| Herpes Virus Infection (Fig. 1.5) | 4 | ||
| Other Viral Infections | 4 | ||
| References | 4 | ||
| Human papillomavirus infection | 4 | ||
| Herpes virus infection | 4 | ||
| Other viral infections | 5 | ||
| Other Infections | 5 | ||
| Syphilis | 5 | ||
| Granuloma Inguinale | 5 | ||
| Lymphogranuloma Venereum | 5 | ||
| Chancroid | 5 | ||
| Tuberculosis | 5 | ||
| Necrotizing Fasciitis and Progressive Bacterial Synergistic Gangrene | 6 | ||
| Other Bacterial Infections | 6 | ||
| Fungal Infections and Parasitic Infestations | 6 | ||
| References | 6 | ||
| Non-Neoplastic Epithelial Disorders | 7 | ||
| Classification* | 7 | ||
| Lichen Sclerosus | 7 | ||
| Clinical and gross features (Fig. 1.6) | 7 | ||
| Microscopic features (Figs. 1.7 and 1.8) | 7 | ||
| Differential diagnosis | 8 | ||
| Behavior | 8 | ||
| Squamous Cell Hyperplasia, NOS (Fig. 1.9) | 8 | ||
| Other Dermatoses (Fig. 1.10) | 8 | ||
| References | 9 | ||
| Squamous Papillomatosis (Fig. 1.11) | 10 | ||
| References | 10 | ||
| Pigmented Lesions | 10 | ||
| Lentigo Simplex and Melanosis (Fig. 1.12) | 10 | ||
| Usual Melanocytic Nevi | 11 | ||
| 1 Abstracts and Keywords | e1 | ||
| Abstract: | e1 | ||
| Keywords: | e1 | ||
| 2 Malignant Tumors of the Vulva | 29 | ||
| Squamous Cell Carcinoma and Its Precursors | 30 | ||
| Vulvar Intraepithelial Neoplasia (VIN) | 30 | ||
| Terminology | 30 | ||
| Clinical features of usual VIN | 30 | ||
| Pathological features of usual VIN and its variants (Figs. 2.1–2.8) | 30 | ||
| Behavior of usual VIN | 32 | ||
| Clinical features of differentiated VIN | 32 | ||
| Microscopic features of differentiated VIN (Figs. 2.9–2.11) | 32 | ||
| Behavior of differentiated VIN | 33 | ||
| Differential diagnosis of usual and differentiated VIN | 33 | ||
| Invasive Squamous Cell Carcinoma of Usual Type | 34 | ||
| Clinical features | 34 | ||
| Pathologic features (Figs. 2.12–2.18) | 34 | ||
| Differential diagnosis | 36 | ||
| Behavior and prognostic factors | 36 | ||
| Verrucous Carcinoma (Figs. 2.19–2.20) | 37 | ||
| Sarcomatoid Squamous Cell Carcinoma (Fig. 2.21) | 37 | ||
| Other Rare Variants of Squamous Cell Carcinoma | 37 | ||
| References | 38 | ||
| Vulvar intraepithelial neoplasia | 38 | ||
| Invasive squamous cell carcinoma: general features | 39 | ||
| Invasive squamous cell carcinoma: behavior and prognostic factors | 39 | ||
| Verrucous carcinoma | 39 | ||
| Sarcomatoid squamous cell carcinoma | 40 | ||
| Other rare variants of squamous cell carcinoma | 40 | ||
| Paget’s Disease | 40 | ||
| Clinical features (Fig. 2.22) | 40 | ||
| Histogenesis | 40 | ||
| Microscopic features (Figs. 2.23–2.28) | 40 | ||
| Differential diagnosis | 42 | ||
| Behavior | 42 | ||
| References | 42 | ||
| Carcinoma of Bartholin’s Gland (Figs. 2.29–2.30) | 43 | ||
| References | 43 | ||
| Other Adenocarcinomas and Related Tumors | 44 | ||
| Adenocarcinoma of Mammary Type (Fig. 2.31) | 44 | ||
| Adenocarcinomas of Skin Appendage Origin (Fig. 2.32) | 44 | ||
| Rare Miscellaneous Adenocarcinomas, Malignant Myoepithelioma, and Carcinoid Tumor | 44 | ||
| References | 45 | ||
| Adenocarcinoma of mammary type | 45 | ||
| Adenocarcinomas of skin appendage origin | 45 | ||
| Rare miscellaneous adenocarcinomas, malignant myoepithelioma, and carcinoid tumor | 45 | ||
| Basal Cell Carcinoma (Fig. 2.33) | 45 | ||
| 2 Abstracts and Keywords | e2 | ||
| Abstract: | e2 | ||
| Keywords: | e2 | ||
| 3 The Vagina | 53 | ||
| Tumor-Like Lesions | 53 | ||
| Condyloma Acuminatum | 53 | ||
| Vaginal Adenosis (Figs. 3.1–3.6) | 53 | ||
| Cysts (Fig. 3.7) | 55 | ||
| Prolapse of Fallopian Tube (Fig. 3.8) | 55 | ||
| Postoperative Spindle Cell Nodule | 56 | ||
| 3 Abstracts and Keywords | e3 | ||
| Abstract: | e3 | ||
| Keywords: | e3 | ||
| 4 Tumor-like Lesions and Benign Tumors of the Uterine Cervix | 73 | ||
| Tumor-Like Lesions | 74 | ||
| Metaplasias and Ectopias | 74 | ||
| Squamous Metaplasia (Figs. 4.1–4.2) | 74 | ||
| Transitional Cell Metaplasia (Fig. 4.3) | 74 | ||
| Tubal, Tuboendometrioid, and Endometrioid Metaplasia | 75 | ||
| General features | 75 | ||
| Microscopic features (Figs. 4.4–4.6) | 75 | ||
| Differential diagnosis | 75 | ||
| Endometriosis (Figs. 4.7–4.8) | 76 | ||
| Endocervicosis (Figs. 4.9–4.10) | 77 | ||
| Endosalpingiosis (Fig. 4.11) | 77 | ||
| Deep Glands and Cysts (Figs. 4.12–4.13) | 78 | ||
| Intestinal Metaplasia | 78 | ||
| Oxyphilic Metaplasia (Fig. 4.14) | 78 | ||
| Ectopic Prostatic Tissue and Ectopic Skene’s Glands (Figs. 4.15–4.16) | 78 | ||
| Other Ectopias (Figs. 4.17–4.18) | 79 | ||
| Endocervical Glandular Hyperplasias | 79 | ||
| Tunnel Clusters (Figs. 4.19–4.20) | 79 | ||
| Microglandular Hyperplasia (Figs. 4.21–4.23) | 80 | ||
| Diffuse Laminar Endocervical Glandular Hyperplasia (Fig. 4.24) | 81 | ||
| Lobular Endocervical Glandular Hyperplasia (Figs. 4.25–4.26) | 82 | ||
| Differential diagnosis | 82 | ||
| Adenoid Basal Hyperplasia (Fig. 4.27) | 82 | ||
| Mesonephric Lesions | 83 | ||
| Mesonephric Remnants (Fig. 4.28) | 83 | ||
| Mesonephric Hyperplasia (Figs. 4.29–4.30) | 83 | ||
| Mesonephric Ductal Hyperplasia (Fig. 4.31) | 84 | ||
| Reactive and Reparative Lesions | 84 | ||
| Postbiopsy Pseudoinvasion of Squamous Epithelium (Fig. 4.32) | 84 | ||
| Reactive and Reparative Atypia (Fig. 4.33) | 84 | ||
| Pagetoid Dyskeratosis | 85 | ||
| Radiation-induced Atypia (Fig. 4.34) | 85 | ||
| Changes Secondary to Extravasation of Mucin (Fig. 4.35) | 85 | ||
| Postoperative Spindle Cell Nodule | 86 | ||
| Pseudoactinomycotic Radiate Granules | 86 | ||
| Inflammatory Lesions | 86 | ||
| Typical Cervicitis | 86 | ||
| Papillary Endocervicitis (Fig. 4.36) | 86 | ||
| Follicular Cervicitis (Fig. 4.37) | 86 | ||
| Florid Reactive Lymphoid Hyperplasia (Lymphoma-like Lesion) (Figs. 4.38–4.39) | 86 | ||
| Plasma Cell Cervicitis | 87 | ||
| Histiocytic Infiltrates and Noninfectious Granulomas (Fig. 4.40) | 87 | ||
| Changes Related to Cautery and Monsel’s Solution (Figs. 4.41–4.44) | 87 | ||
| Eosinophilic Cervicitis | 88 | ||
| Ligneous Cervicitis (Fig. 4.45) | 88 | ||
| Pyoderma Gangrenosum | 89 | ||
| Arteritis (Fig. 4.46) | 89 | ||
| Infectious Lesions | 89 | ||
| Viral Lesions (Figs. 4.47–4.48) | 89 | ||
| Bacterial Lesions | 90 | ||
| Parasitic Lesions | 90 | ||
| Pregnancy-Related Changes | 90 | ||
| Ectopic Decidua (Fig. 4.49) | 90 | ||
| Arias-Stella Reaction (Fig. 4.50) | 90 | ||
| Placental Site Nodules and Plaques | 91 | ||
| Cervical Pregnancy (Fig. 4.51) | 91 | ||
| Melanotic Lesions | 91 | ||
| Blue Nevus (Fig. 4.52) | 91 | ||
| Mucosal Melanosis | 91 | ||
| Miscellaneous Tumor-Like Lesions | 91 | ||
| Multinucleated Stromal Giant Cells (Fig. 4.53) | 91 | ||
| Signet-ring-like Epithelial Cells | 92 | ||
| Amyloidosis | 92 | ||
| Psammomatous Calcification (Fig. 4.54) | 92 | ||
| Myxoid Change | 92 | ||
| Extramedullary Hematopoiesis | 92 | ||
| References | 92 | ||
| Transitional cell metaplasia | 92 | ||
| Tubal and tuboendometrioid metaplasia | 92 | ||
| Endometriosis | 93 | ||
| Endocervicosis | 93 | ||
| Endosalpingiosis | 93 | ||
| Deep glands and cysts | 93 | ||
| Intestinal metaplasia | 93 | ||
| Oxyphilic metaplasia | 93 | ||
| Ectopic prostatic tissue and ectopic Skene’s glands | 93 | ||
| Other ectopias | 93 | ||
| Tunnel clusters | 93 | ||
| Microglandular hyperplasia | 93 | ||
| Diffuse laminar endocervical glandular hyperplasia | 93 | ||
| Lobular endocervical glandular hyperplasia | 93 | ||
| Adenoid basal hyperplasia | 94 | ||
| Mesonephric hyperplasia | 94 | ||
| Postbiopsy pseudoinvasion of squamous epithelium | 94 | ||
| Reactive and reparative atypia | 94 | ||
| Pagetoid dyskeratosis | 94 | ||
| Radiation-induced atypia | 94 | ||
| Pseudoactinomycotic radiate granules | 94 | ||
| Follicular cervicitis | 94 | ||
| Florid reactive lymphoid hyperplasia (lymphoma-like lesion) | 94 | ||
| Plasma cell cervicitis | 94 | ||
| Histiocytic infiltrates and noninfectious granulomas | 94 | ||
| Changes related to cautery and Monsel’s solution | 95 | ||
| Eosinophilic cervicitis | 95 | ||
| Ligneous cervicitis | 95 | ||
| Pyoderma gangrenosum | 95 | ||
| Arteritis | 95 | ||
| Viral lesions | 95 | ||
| Bacterial lesions | 95 | ||
| Parasitic lesions | 95 | ||
| Ectopic decidua | 95 | ||
| Arias-Stella reaction | 95 | ||
| Cervical pregnancy | 95 | ||
| Mucosal melanosis | 95 | ||
| Multinucleated stromal giant cells | 95 | ||
| Signet-ring-like epithelial cells | 95 | ||
| Amyloidosis | 95 | ||
| Psammomatous calcification | 96 | ||
| Benign Tumors | 96 | ||
| Epithelial | 96 | ||
| Endocervical Polyps (see Figs. 4.1, 4.21, 4.55, 4.56) | 96 | ||
| Squamous Papilloma | 97 | ||
| Inverted Transitional Cell Papilloma | 97 | ||
| Müllerian Papilloma | 97 | ||
| Mixed Epithelial and Mesenchymal Tumors | 97 | ||
| Adenofibroma | 97 | ||
| Villous and Villoglandular Adenoma | 97 | ||
| Adenomyoma of Endocervical Type (Figs. 4.57–4.59) | 97 | ||
| Differential diagnosis | 98 | ||
| Mesenchymal Tumors | 98 | ||
| References | 98 | ||
| Endocervical polyps | 98 | ||
| Squamous papilloma | 99 | ||
| Inverted transitional cell papilloma | 99 | ||
| Müllerian papilloma | 99 | ||
| Villous and villoglandular adenomas | 99 | ||
| Adenomyoma of endocervical type | 99 | ||
| Mesenchymal tumors | 99 | ||
| 4 Abstracts and Keywords | e4 | ||
| Abstract: | e4 | ||
| Keywords: | e4 | ||
| 5 Invasive Squamous Cell Carcinoma of the Cervix and its Precursors | 100 | ||
| Precursor Lesions | 100 | ||
| Classification | 100 | ||
| Risk factors | 100 | ||
| Clinical features (Fig. 5.1) | 101 | ||
| Microscopic features of LSILs (Figs. 5.2–5.8) | 101 | ||
| Microscopic features of HSILs (Figs. 5.9–5.17) | 102 | ||
| Topography of SILs | 105 | ||
| Features of SILs suggesting the presence of early invasion | 105 | ||
| Differential diagnosis of SILs (Figs. 5.18–5.23) | 105 | ||
| Natural history | 107 | ||
| References | 108 | ||
| General | 108 | ||
| SILs of unusual types and locations, atypias, and metaplastic lesions | 108 | ||
| Immunohistochemistry and molecular findings | 108 | ||
| SUPERFICIALLY Invasive Squamous Cell Carcinomas (Stage IA) | 109 | ||
| Clinical features | 109 | ||
| Microscopic features (Figs. 5.24–5.26) | 110 | ||
| Differential diagnosis | 110 | ||
| Prognosis and behavior of Ia1 lesions | 110 | ||
| Prognosis and behavior of Ia2 lesions | 111 | ||
| References | 111 | ||
| Invasive Squamous Cell Carcinoma | 111 | ||
| Clinical features | 111 | ||
| Gross features (Fig. 5.27) | 111 | ||
| Usual microscopic features (Figs. 5.28–5.30) | 111 | ||
| Unusual microscopic features (Figs. 5.31–5.34) | 112 | ||
| Differential diagnosis | 114 | ||
| Prognostic factors | 114 | ||
| References | 115 | ||
| General and prognostic | 115 | ||
| Unusual subtypes and findings | 115 | ||
| Variants of Squamous Cell Carcinoma | 116 | ||
| Basaloid Squamous Cell Carcinoma (Fig. 5.35) | 116 | ||
| Verrucous Carcinoma | 116 | ||
| Warty or Condylomatous Carcinoma | 116 | ||
| Papillary Squamous Cell Carcinoma (Figs. 5.36–5.37) | 116 | ||
| Lymphoepithelioma-like Carcinoma (Fig. 5.38) | 117 | ||
| Papillary Transitional Cell Carcinoma and Squamotransitional Cell Carcinomas (Fig. 5.39) | 117 | ||
| Sarcomatoid Squamous Cell Carcinoma (Fig. 5.40) | 118 | ||
| Mucoepidermoid Carcinoma | 118 | ||
| References | 118 | ||
| Basaloid squamous cell carcinoma | 118 | ||
| Verrucous carcinoma | 118 | ||
| Papillary squamous cell carcinoma | 118 | ||
| Lymphoepithelioma-like carcinoma | 118 | ||
| Papillary transitional cell carcinoma and squamotransitional cell carcinomas | 119 | ||
| Sarcomatoid squamous cell carcinoma | 119 | ||
| Mucoepidermoid carcinoma | 119 | ||
| 5 Abstracts and Keywords | e5 | ||
| Abstract: | e5 | ||
| Keywords: | e5 | ||
| 6 Adenocarcinomas of the Cervix, Related Tumors, and Their Precursors | 120 | ||
| Preinvasive Glandular Lesions and Early Invasive Adenocarcinomas | 120 | ||
| Adenocarcinoma in Situ (AIS) | 120 | ||
| Clinical features | 120 | ||
| Microscopic features (Figs. 6.1–6.7) | 121 | ||
| Evidence supporting precancerous potential | 123 | ||
| Differential diagnosis | 123 | ||
| Behavior | 123 | ||
| Endocervical Glandular Dysplasia (EGD) | 123 | ||
| Early Invasive Adenocarcinoma (Stage Ia Adenocarcinoma) | 123 | ||
| Microscopic features (Figs. 6.8–6.9) | 124 | ||
| Behavior | 124 | ||
| References | 125 | ||
| Adenocarcinoma in situ | 125 | ||
| Endocervical glandular dysplasia (EGD) | 125 | ||
| Early invasive adenocarcinoma | 125 | ||
| Invasive Adenocarcinomas | 126 | ||
| Clinical findings and prognostic features | 126 | ||
| Endocervical Adenocarcinoma, Usual Type (Figs. 6.10–6.19) | 127 | ||
| Differential diagnosis | 129 | ||
| Variant: Well-differentiated Villoglandular Adenocarcinoma (Figs. 6.20–6.21) | 130 | ||
| Mucinous Carcinomas, including Gastric-type Adenocarcinoma (Figs. 6.22–6.23) | 130 | ||
| Differential diagnosis | 131 | ||
| Variant: Adenoma Malignum (Minimal Deviation Adenocarcinoma) (Figs. 6.24–6.29) | 132 | ||
| Variant: Intestinal-type Adenocarcinomas, Including Signet-ring Cell Adenocarcinoma and Colloid Adenocarcinoma (Fig. 6.30) | 133 | ||
| Endometrioid Adenocarcinoma (Fig. 6.31) | 134 | ||
| Differential diagnosis | 134 | ||
| Variant: Minimal Deviation Endometrioid Adenocarcinoma (Fig. 6.32) | 134 | ||
| Clear Cell Adenocarcinoma (Figs. 6.33–6.34) | 135 | ||
| Differential diagnosis | 135 | ||
| Serous Adenocarcinoma (Fig. 6.35) | 135 | ||
| Differential diagnosis | 136 | ||
| Mesonephric Adenocarcinoma and Malignant Mixed Mesonephric Tumors (Fig. 6.36) | 136 | ||
| Differential diagnosis | 137 | ||
| Adenosquamous Carcinoma (Figs. 6.37–6.38) | 137 | ||
| Glassy Cell Carcinoma (Fig. 6.39) | 138 | ||
| Adenoid Basal Carcinoma (Adenoid Basal Epithelioma) (Figs. 6.40–6.44) | 138 | ||
| Differential diagnosis | 140 | ||
| Adenoid Cystic Carcinoma (Figs. 6.45–6.46) | 140 | ||
| Differential diagnosis | 141 | ||
| References | 141 | ||
| Clinical findings and prognostic features | 141 | ||
| Endocervical adenocarcinoma of usual type | 141 | ||
| Well-differentiated villoglandular adenocarcinoma | 141 | ||
| Mucinous carcinomas including gastric-type adenocarcinomas | 142 | ||
| Intestinal-type adenocarcinomas, including signet-ring cell adenocarcinoma and colloid adenocarcinoma | 142 | ||
| Endometrioid adenocarcinoma | 142 | ||
| Clear cell adenocarcinoma | 142 | ||
| Serous adenocarcinoma | 142 | ||
| Mesonephric adenocarcinoma | 143 | ||
| Adenosquamous carcinoma | 143 | ||
| Glassy cell carcinoma | 143 | ||
| Adenoid basal carcinoma | 143 | ||
| Adenoid cystic carcinoma | 143 | ||
| Neuroendocrine Tumors | 144 | ||
| Typical and Atypical Carcinoid Tumors | 144 | ||
| Small Cell (Neuroendocrine) Carcinoma | 144 | ||
| Clinical features | 144 | ||
| Pathological features (Figs. 6.47–6.48) | 144 | ||
| Differential diagnosis | 145 | ||
| Behavior and prognostic factors | 145 | ||
| Large Cell Neuroendocrine Carcinoma (Figs. 6.49–6.52) | 145 | ||
| Differential diagnosis | 146 | ||
| References | 146 | ||
| Typical and atypical carcinoid tumors | 146 | ||
| Small cell (neuroendocrine) carcinoma | 146 | ||
| Large cell neuroendocrine carcinoma | 147 | ||
| Metastatic adenocarcinomas (see Chapter 10) | 147 | ||
| 6 Abstracts and Keywords | e6 | ||
| Abstract: | e6 | ||
| Keywords: | e6 | ||
| 7 Non-neoplastic Lesions of the Uterine Corpus | 148 | ||
| Changes Related to Menses and Atrophy | 149 | ||
| Menses-related Changes (Figs. 7.1 and 7.5) | 149 | ||
| Atrophy-related Changes | 149 | ||
| References | 149 | ||
| Curettage-Related Changes (Figs. 7.2–7.4) | 151 | ||
| Epithelial Metaplasias | 151 | ||
| Syncytial Papillary Change (Fig. 7.5) | 152 | ||
| Squamous and Morular Metaplasia (Figs. 7.6–7.7 and 7.19) | 152 | ||
| Mucinous (including Intestinal) Metaplasia (Fig. 7.8) | 153 | ||
| Ciliated (Tubal) Metaplasia (Figs. 7.9–7.10) | 154 | ||
| Eosinophilic and Oncocytic Metaplasia (Fig. 7.11) | 154 | ||
| Hobnail Cell Metaplasia | 155 | ||
| Clear Cell Metaplasia (Fig. 7.12) | 155 | ||
| Mesonephric-like Metaplasia | 155 | ||
| References | 155 | ||
| General | 155 | ||
| Syncytial papillary change | 155 | ||
| Squamous and morular metaplasia | 155 | ||
| Mucinous and intestinal metaplasia | 156 | ||
| Other types | 156 | ||
| Pregnancy-Related and Hormonal Changes | 156 | ||
| Arias-Stella Reaction (Fig. 7.13) | 156 | ||
| Clear Cell Change | 156 | ||
| Optically Clear Nuclei (Fig. 7.14) | 156 | ||
| Decidua (Figs. 7.15–7.16) | 157 | ||
| Effects of Exogenous Hormones (Figs. 7.17–7.20) | 157 | ||
| Heterotopic Tissues (Fig. 7.21) | 159 | ||
| References | 159 | ||
| Inflammatory and Reparative Lesions | 160 | ||
| Chronic Endometritis (Figs. 7.22–7.24) | 160 | ||
| Microscopic findings | 160 | ||
| Clinicopathologic correlation and differential diagnosis | 161 | ||
| Focal Necrotizing Endometritis (Fig. 7.25) | 161 | ||
| Florid Reactive Lymphoid Hyperplasia (Lymphoma-like Lesion) (Fig. 7.26) | 161 | ||
| Granulomatous Endometritis, including Effects of Thermal Ablation (Figs. 7.27–7.28) | 162 | ||
| Xanthogranulomatous Endometritis and Myometrial Xanthomatosis (Fig. 7.29) | 162 | ||
| Malacoplakia (Fig. 7.30) | 163 | ||
| Histiocytic Nodules (Fig. 7.31) | 163 | ||
| Eosinophilic Infiltrates | 164 | ||
| Mast Cell Infiltrates | 164 | ||
| Ligneous Endometritis | 164 | ||
| Pneumopolycystic Endometritis | 164 | ||
| Postoperative Spindle Cell Nodule | 164 | ||
| Intrauterine Device-related Changes, including Actinomycosis (Figs. 7.32–7.33) | 164 | ||
| Radiation-induced Changes (Fig. 7.34) | 165 | ||
| Arteritis | 165 | ||
| Viral Lesions | 165 | ||
| References | 165 | ||
| Chronic endometritis | 165 | ||
| Focal necrotizing endometritis | 166 | ||
| Florid reactive lymphoid hyperplasia (lymphoma-like lesion) | 166 | ||
| Granulomatous endometritis, including effects of thermal ablation | 166 | ||
| Xanthogranulomatous endometritis and myometrial xanthomatosis | 166 | ||
| Malacoplakia | 166 | ||
| Histiocytic nodules | 166 | ||
| Eosinophilic infiltrates | 166 | ||
| Mast cell infiltrates | 166 | ||
| Ligneous endometritis | 166 | ||
| Pneumopolycystic endometritis | 166 | ||
| Postoperative spindle cell nodule | 166 | ||
| Intrauterine device-related changes, including actinomycosis | 166 | ||
| Radiation-induced changes | 166 | ||
| Viral infections | 166 | ||
| Endometrial Polyps (Figs. 7.35–7.40, 7.46) | 167 | ||
| Clinical and gross features | 167 | ||
| Microscopic features | 168 | ||
| Differential diagnosis | 169 | ||
| 7 Abstracts and Keywords | e7 | ||
| Abstract: | e7 | ||
| Keywords: | e7 | ||
| 8 Endometrial Hyperplasia and Carcinoma | 176 | ||
| Endometrial Hyperplasia | 176 | ||
| Classification | 176 | ||
| Clinical features | 177 | ||
| Pathological features (Figs. 8.1–8.4) | 177 | ||
| Behavior | 178 | ||
| Differential diagnosis (Fig. 8.5) | 179 | ||
| References | 180 | ||
| General | 180 | ||
| Immunohistochemistry, molecular findings, and EIN | 180 | ||
| Endometrial Carcinoma | 181 | ||
| Classification | 181 | ||
| Gross features (Fig. 8.6) | 181 | ||
| Endometrioid Carcinoma, Usual Type | 181 | ||
| Clinical and general features | 181 | ||
| Typical microscopic features (Figs. 8.7–8.12) | 182 | ||
| Squamous differentiation (Figs. 8.13–8.15) | 183 | ||
| Unusual patterns including microglandular, sertoliform, and CHEC (Figs. 8.16–8.18) | 185 | ||
| Unusual cell types including ciliated, oxyphilic, clear, and spindle (Figs. 8.19–8.22) | 186 | ||
| Patterns of myometrial invasion (Figs. 8.23–8.28) | 186 | ||
| Findings often over-interpreted as myometrial invasion (Fig. 8.29–8.30) | 189 | ||
| Grading | 190 | ||
| Patterns of cervical involvement (Fig. 8.31) | 190 | ||
| Carcinomas arising in unusual locations | 191 | ||
| Carcinomas related to Lynch syndrome and other disorders with mismatch repair protein defects (Fig. 8.32) | 192 | ||
| Effects of treatment | 192 | ||
| Immunohistochemical and molecular findings | 193 | ||
| Markers helpful in distinction from endocervical adenocarcinoma | 193 | ||
| Markers helpful in the distinction from serous carcinomas (see corresponding heading) | 193 | ||
| Markers of potential prognostic and therapeutic significance | 193 | ||
| Findings in recurrences | 194 | ||
| Differential diagnosis | 194 | ||
| Prognostic factors | 194 | ||
| Endometrioid Carcinoma, Unusual Types | 195 | ||
| Secretory Carcinoma (Figs. 8.33–8.34) | 195 | ||
| Villoglandular Endometrioid Carcinoma (Figs. 8.35–8.36) | 196 | ||
| Endometrioid Carcinoma with Small Nonvillous Papillae (Fig. 8.37) | 197 | ||
| Ciliated Carcinoma | 197 | ||
| Serous Carcinoma | 197 | ||
| Clinical features | 197 | ||
| Pathological features (Figs. 8.38–8.46) | 198 | ||
| Immunohistochemical findings | 200 | ||
| Molecular findings | 200 | ||
| Behavior and prognostic factors | 201 | ||
| Differential diagnosis (Table 8.3) | 201 | ||
| Clear Cell Carcinoma | 202 | ||
| Clinical features | 202 | ||
| Pathologic features (Figs. 8.47–8.48) | 202 | ||
| Behavior and prognostic features | 203 | ||
| Differential diagnosis (Table 8.4) | 203 | ||
| Mucinous carcinoma | 203 | ||
| Clinical features | 203 | ||
| Pathologic features (Figs. 8.49–8.51) | 204 | ||
| Behavior | 204 | ||
| Differential diagnosis | 204 | ||
| Squamous Cell Carcinoma | 205 | ||
| Clinical features | 205 | ||
| Criteria for diagnosis | 205 | ||
| Pathological features (Figs. 8.52–8.53) | 205 | ||
| 8 Abstracts and Keywords | e8 | ||
| Abstract: | e8 | ||
| Keywords: | e8 | ||
| 9 Mesenchymal and Mixed Epithelial–Mesenchymal Tumors of the Uterine Corpus and Cervix | 218 | ||
| Smooth Muscle Tumors | 219 | ||
| Leiomyoma, Usual Type | 219 | ||
| Clinical features | 219 | ||
| Usual gross features (Fig. 9.1) | 219 | ||
| Usual microscopic features (Figs. 9.2–9.5) | 219 | ||
| Hormonal and pregnancy-related changes | 221 | ||
| Changes secondary to uterine artery embolization and antifibrinolytic agents (Fig. 9.6) | 221 | ||
| Leiomyoma Variants | 221 | ||
| Cellular Leiomyoma and Highly Cellular Leiomyoma (Figs. 9.7–9.10) | 221 | ||
| Leiomyomas with Bizarre Nuclei (LBNs) (Figs. 9.11–9.12) | 223 | ||
| Mitotically Active Leiomyoma | 224 | ||
| Hydropic Leiomyoma (Figs. 9.13–9.16) | 224 | ||
| Myxoid Leiomyoma (Fig. 9.17) | 225 | ||
| Apoplectic Leiomyoma (Fig. 9.18) | 226 | ||
| Leiomyomas with Rare Findings (Fig. 9.19) | 226 | ||
| Leiomyosarcoma | 227 | ||
| Leiomyosarcoma of Usual Type | 227 | ||
| Clinical features | 227 | ||
| Gross features (Fig. 9.20) | 227 | ||
| Typical microscopic features (Figs. 9.21–9.22) | 227 | ||
| Rare microscopic features | 229 | ||
| Immunohistochemical and molecular features | 229 | ||
| Behavior and prognosis | 229 | ||
| Differential diagnosis | 230 | ||
| Myxoid Leiomyosarcoma (Figs. 9.23–9.25) | 230 | ||
| Epithelioid Leiomyosarcoma (see Epithelioid Smooth Muscle Tumors) | 231 | ||
| Smooth Muscle Tumors of Uncertain Malignant Potential | 231 | ||
| Epithelioid Smooth Muscle Tumors | 232 | ||
| General features | 232 | ||
| Pathological features (Figs. 9.26–9.30) | 232 | ||
| Criteria for epithelioid leiomyosarcoma and its behavior | 233 | ||
| Differential diagnosis | 233 | ||
| Tumors of Perivascular Epithelioid Cell Origin | 233 | ||
| Perivascular Epithelioid Cell Tumors of Usual Type (PEComas) (Figs. 9.31–9.32) | 233 | ||
| Differential diagnosis | 235 | ||
| Angiomyolipoma | 235 | ||
| Lymphangioleiomyomatosis (Fig. 9.33) | 235 | ||
| Benign-Appearing Smooth Muscle Tumors with Unusual Growth Patterns or Behavior | 235 | ||
| Low-grade Smooth Muscle Tumor of Probable Multicentric Origin | 235 | ||
| Diffuse Uterine Leiomyomatosis | 236 | ||
| Dissecting Leiomyoma, including the Cotyledonoid Variant (Fig. 9.34) | 236 | ||
| Leiomyoma with Vascular Invasion | 237 | ||
| Intravenous Leiomyomatosis | 237 | ||
| Clinical features | 237 | ||
| Pathological features (Figs. 9.35–9.37) | 237 | ||
| Differential diagnosis (Fig. 9.38) | 237 | ||
| Behavior | 238 | ||
| Benign Metastasizing Leiomyoma (Fig. 9.39) | 239 | ||
| ‘Parasitic’ Leiomyoma | 239 | ||
| Disseminated Peritoneal Leiomyomatosis (see Chapter 19) | 239 | ||
| References | 239 | ||
| Leiomyomas: general features | 239 | ||
| Leiomyomas: treatment-related findings | 239 | ||
| Cellular leiomyoma and highly cellular leiomyoma | 240 | ||
| Leiomyomas with bizarre nuclei (LBNs) | 240 | ||
| Mitotically active leiomyoma | 240 | ||
| Hydropic leiomyoma | 240 | ||
| Myxoid leiomyoma | 240 | ||
| Apoplectic leiomyoma | 240 | ||
| Leiomyomas with rare findings | 240 | ||
| Leiomyosarcoma: usual findings | 241 | ||
| Leiomyosarcoma: immunohistochemical and molecular findings | 241 | ||
| Leiomyosarcoma: unusual findings | 241 | ||
| Myxoid leiomyosarcoma | 241 | ||
| Smooth muscle tumors of uncertain malignant potential | 241 | ||
| Epithelioid smooth muscle tumors | 242 | ||
| Perivascular epithelioid cell tumors | 242 | ||
| Low-grade smooth muscle tumors of probable multicentric origin | 242 | ||
| Diffuse uterine leiomyomatosis | 242 | ||
| Dissecting leiomyoma, including the cotyledonoid variant | 242 | ||
| Leiomyoma with vascular invasion | 242 | ||
| Intravenous leiomyomatoisis | 242 | ||
| Benign metastasizing leiomyoma | 243 | ||
| ‘Parasitic’ leiomyoma | 243 | ||
| Endometrial Stromal and Related Tumors | 243 | ||
| Endometrial Stromal Nodule and Endometrial Stromal Tumor with Limited Infiltration | 243 | ||
| Clinical and usual pathological features (Figs. 9.40–9.43) | 243 | ||
| Differential diagnosis | 244 | ||
| Low-Grade Endometrial Stromal Sarcoma | 245 | ||
| Clinical features | 245 | ||
| Usual pathological features (Figs. 9.44–9.48) | 245 | ||
| Usual immunohistochemical findings | 245 | ||
| Cytogenetic findings | 246 | ||
| Unusual pathological features of endometrial stromal tumors (Figs. 9.49–9.60) | 246 | ||
| Fibrous and myxoid change | 246 | ||
| Smooth muscle differentiation | 248 | ||
| Sex-cord-like elements | 249 | ||
| Glands | 249 | ||
| Papillae and pseudopapillae | 249 | ||
| Epithelioid cells | 249 | ||
| Associated high-grade component | 249 | ||
| YWHAE-FAM22 ESSs | 250 | ||
| Other Rare Findings | 250 | ||
| Differential diagnosis | 250 | ||
| Behavior and prognostic features | 250 | ||
| Undifferentiated Endometrial Sarcoma (Fig. 9.61) | 251 | ||
| Differential diagnosis | 251 | ||
| Endocervical Stromal Sarcoma | 252 | ||
| References | 252 | ||
| Endometrial stromal nodule and endometrial stromal tumor with limited infiltration | 252 | ||
| Endometrial stromal sarcomas: general features | 252 | ||
| Endometrial stromal sarcomas: usual immunohistochemical and molecular findings | 252 | ||
| Endometrial stromal tumors with unusual features | 252 | ||
| Undifferentiated endometrial sarcoma | 253 | ||
| Endocervical stromal sarcoma | 253 | ||
| Mixed Epithelial and Mesenchymal Tumors | 253 | ||
| Malignant Müllerian Mixed Tumor | 253 | ||
| Nomenclature and histogenesis | 253 | ||
| Clinical features | 253 | ||
| Gross appearance (Fig. 9.62) | 254 | ||
| Microscopic appearance (Figs. 9.63–9.64) | 254 | ||
| Immunohistochemical and molecular findings | 255 | ||
| Differential diagnosis | 255 | ||
| Behavior and prognostic factors | 255 | ||
| Müllerian Adenofibroma (Fig. 9.65) | 255 | ||
| Müllerian Adenosarcoma | 256 | ||
| Typical | 256 | ||
| Clinical features | 256 | ||
| Gross appearance (Fig. 9.66) | 256 | ||
| Microscopic appearance (Figs. 9.67–9.71) | 256 | ||
| Differential diagnosis | 258 | ||
| Behavior | 259 | ||
| With Sarcomatous Overgrowth (Fig. 9.72) | 259 | ||
| Müllerian Carcinofibroma and Carcinomesenchymoma | 259 | ||
| Adenomyomas | 259 | ||
| Of Endocervical Type (see Chapter 4) | 259 | ||
| Of Typical Endometrioid Type (Figs. 9.73–9.74) | 259 | ||
| Atypical Polypoid Adenomyoma | 260 | ||
| Clinical and gross findings (Fig. 9.75) | 260 | ||
| Microscopic findings (Figs. 9.76–9.77) | 261 | ||
| Differential diagnosis | 262 | ||
| Behavior | 262 | ||
| Uterine Tumors Resembling Ovarian Sex-Cord Tumors | 262 | ||
| Clinical features | 262 | ||
| Pathological features (Figs. 9.78–9.83) | 262 | ||
| Differential diagnosis | 264 | ||
| Behavior | 264 | ||
| References | 264 | ||
| MMMTs: usual features | 264 | ||
| MMMTs: unusual pathologic features | 264 | ||
| MMMTs: immunohistochemistry and molecular studies | 265 | ||
| Müllerian adenofibroma | 265 | ||
| Müllerian adenosarcoma | 265 | ||
| Müllerian carcinofibroma and carcinomesenchymoma | 265 | ||
| Adenomyoma of typical endometrioid type | 265 | ||
| Atypical polypoid adenomyoma | 266 | ||
| Uterine tumors resembling ovarian sex-cord tumors | 266 | ||
| Rare Sarcomas | 266 | ||
| Homologous Sarcomas | 266 | ||
| Vascular Tumors | 266 | ||
| Malignant Fibrous Histiocytoma and Giant Cell Tumors | 266 | ||
| Malignant Peripheral Nerve Sheath Tumors (Fig. 9.84) | 267 | ||
| Heterologous Sarcomas | 267 | ||
| Embryonal Rhabdomyosarcoma (including Sarcoma Botryoides) (Figs. 9.85–9.86) | 267 | ||
| Differential diagnosis | 268 | ||
| Rare Heterologous Sarcomas | 268 | ||
| Extragastrointestinal Stromal Tumors | 268 | ||
| Sarcomas of Uncertain Histogenesis | 268 | ||
| Alveolar Soft Part Sarcoma | 268 | ||
| Malignant Rhabdoid Tumor | 268 | ||
| Epithelioid Sarcoma | 268 | ||
| References | 269 | ||
| Vascular tumors | 269 | ||
| Malignant fibrous histiocytoma and giant cell tumors | 269 | ||
| Malignant peripheral nerve sheath tumors | 269 | ||
| Embryonal rhabdomyosarcoma | 269 | ||
| Rare heterologous sarcomas | 269 | ||
| Extragastrointestinal stromal tumors | 269 | ||
| Alveolar soft part sarcoma | 269 | ||
| Malignant rhabdoid tumor | 269 | ||
| Epithelioid sarcoma | 269 | ||
| Benign Mesenchymal Tumors of Soft Tissue Type | 270 | ||
| Inflammatory Myofibroblastic Tumor (Fig. 9.87) | 270 | ||
| Others | 270 | ||
| References | 270 | ||
| Inflammatory myofibroblastic tumor | 270 | ||
| Other benign mesenchymal tumors of soft tissue type | 270 | ||
| Acknowledgment | 270 | ||
| 9 Abstracts and Keywords | e9 | ||
| Abstract: | e9 | ||
| Keywords: | e9 | ||
| 10 Trophoblastic Lesions, Miscellaneous Primary Uterine Neoplasms, Hematopoietic Neoplasms, and Metastatic Neoplasms to the Uterus | 271 | ||
| Trophoblastic Lesions | 272 | ||
| Hydatidiform Moles | 272 | ||
| Complete Hydatidiform Mole | 272 | ||
| Clinical and cytogenetic features | 272 | ||
| Pathological features (Figs.10.2–10.5) | 273 | ||
| Differential diagnosis | 274 | ||
| Behavior | 275 | ||
| Partial Hydatidiform Mole | 276 | ||
| Clinical and cytogenetic features | 276 | ||
| Pathological features (Figs.10.6–10.7) | 276 | ||
| Differential diagnosis | 277 | ||
| Behavior | 277 | ||
| Hydropic Abortus (Fig. 10.8) | 277 | ||
| Choriocarcinoma | 278 | ||
| Clinical features | 278 | ||
| Pathological features (Figs. 10.9–10.10) | 278 | ||
| Differential diagnosis | 279 | ||
| Behavior | 279 | ||
| Lesions of Intermediate Trophoblast | 279 | ||
| Normal Intermediate Trophoblast (Fig. 10.11) | 279 | ||
| Exaggerated Placental Site (Figs. 10.12–10.13) | 280 | ||
| Placental Site Nodules and Plaques | 280 | ||
| Clinical findings | 280 | ||
| Pathological findings (Figs. 10.14–10.17) | 281 | ||
| Differential diagnosis | 281 | ||
| Placental Site Trophoblastic Tumor (Figs. 10.18–10.20) | 282 | ||
| Clinical features | 282 | ||
| Gross features | 283 | ||
| Microscopic and molecular features | 283 | ||
| Differential diagnosis | 283 | ||
| Behavior | 284 | ||
| Epithelioid Trophoblastic Tumor (Figs. 10.21–10.22) | 284 | ||
| Differential diagnosis | 284 | ||
| Tumor-Like Abnormalities of Placentation | 285 | ||
| Placental Polyps (Fig. 10.23) | 285 | ||
| Placenta Accreta, Increta, and Percreta | 285 | ||
| References | 285 | ||
| Hydatidiform moles | 285 | ||
| Choriocarcinoma | 286 | ||
| Exaggerated placental site | 286 | ||
| Placental site nodule | 286 | ||
| Placental site trophoblastic tumor | 286 | ||
| Epithelioid trophoblastic tumor | 286 | ||
| Placenta accreta, increta, and percreta | 287 | ||
| Miscellaneous Primary Tumors | 287 | ||
| Adenomatoid Tumor | 287 | ||
| General features | 287 | ||
| Pathological features (Figs. 10.24–10.26) | 287 | ||
| Differential diagnosis | 288 | ||
| Germ Cell Tumors | 288 | ||
| Yolk Sac Tumor | 288 | ||
| Teratomas | 288 | ||
| Neuroectodermal Tumors | 289 | ||
| Primitive Neuroectodermal Tumor (PNETs) | 289 | ||
| Differential diagnosis | 289 | ||
| Pigmented Neuroectodermal Tumor of Infancy | 289 | ||
| Uterine Glioma | 289 | ||
| Other Neuroectodermal Tumors | 289 | ||
| Wilms’ Tumor | 289 | ||
| Malignant Melanoma | 290 | ||
| Clinical features | 290 | ||
| Pathological findings | 290 | ||
| Differential diagnosis | 290 | ||
| Brenner Tumor | 290 | ||
| References | 290 | ||
| Adenomatoid tumor | 290 | ||
| Yolk sac tumor | 290 | ||
| Teratomas | 290 | ||
| Primitive neuroectodermal tumor | 290 | ||
| Pigmented neuroectodermal tumor of infancy | 291 | ||
| Uterine glioma | 291 | ||
| Other neuroectodermal tumors | 291 | ||
| Wilms’ tumor | 291 | ||
| Malignant melanoma | 291 | ||
| Brenner tumor | 291 | ||
| HematopoIetic and Histiocytic Disorders | 291 | ||
| Lymphoma | 291 | ||
| Lymphoma Presenting in the Uterus (Figs. 10.27–10.30) | 291 | ||
| Clinical features | 291 | ||
| Gross features | 292 | ||
| Microscopic features | 292 | ||
| Differential diagnosis | 292 | ||
| Behavior | 293 | ||
| Uterine Involvement in Patients with Disseminated Lymphoma | 293 | ||
| Uterine Involvement by Leukemia (Fig. 10.31) | 293 | ||
| Leukemia Presenting in the Uterus | 293 | ||
| Uterine Involvement in Patients with Recognized Leukemia | 294 | ||
| Plasmacytoma | 294 | ||
| Uterine Involvement by Histiocytic Disorders (Figs. 10.32–10.33) | 294 | ||
| References | 294 | ||
| Uterine involvement by lymphoma | 294 | ||
| Uterine involvement by leukemia | 295 | ||
| Plasmacytoma | 295 | ||
| Uterine involvement by histiocytic disorders | 295 | ||
| Metastatic Carcinomas to the Uterus | 295 | ||
| From Genital Tract Carcinomas | 295 | ||
| From Extragenital Carcinomas (Figs. 10.34–10.36) | 295 | ||
| References | 297 | ||
| 10 Abstracts and Keywords | e10 | ||
| Abstract: | e10 | ||
| Keywords: | e10 | ||
| 11 The Fallopian Tube and Broad Ligament | 298 | ||
| Tumor-Like Lesions of the Fallopian Tube | 299 | ||
| Inflammatory Lesions | 299 | ||
| Usual Bacterial Salpingitis (Figs. 11.1–11.5) | 299 | ||
| Actinomycotic Salpingitis | 300 | ||
| Tuberculous Salpingitis (Fig. 11.6) | 300 | ||
| Other Causes of Granulomatous and Histiocytic Salpingitis (Figs. 11.7–11.10) | 300 | ||
| Ligneous Salpingitis | 301 | ||
| Arteritis (Fig. 11.11) | 301 | ||
| Epithelial Hyperplasia | 301 | ||
| Usual Type (Figs. 11.12–11.13) | 301 | ||
| Differential diagnosis | 301 | ||
| Papillary Tubal Hyperplasia including Secretory Cell Outgrowths (SCOUTs) (Fig. 11.14) | 302 | ||
| Pregnancy-Related CHANGES | 302 | ||
| Ectopic Pregnancy (Figs. 11.15–11.16) | 302 | ||
| Hydatidiform Mole | 303 | ||
| Placental Site Nodule | 303 | ||
| Arias-Stella Reaction (Fig. 11.17) | 303 | ||
| Clear Cell Change of Pregnancy | 303 | ||
| Ectopic Decidua (Fig. 11.18) | 303 | ||
| Metaplasias and Ectopias | 303 | ||
| Endometriosis (Fig. 11.19) | 303 | ||
| Mucinous Metaplasia (Fig. 11.20) | 304 | ||
| Transitional Cell and Squamous Metaplasia (Fig. 11.21) | 304 | ||
| Metaplastic Papillary ‘Tumor’ (Fig. 11.22) | 305 | ||
| Rare Ectopic Tissues (Figs. 11.23–11.24) | 305 | ||
| Miscellaneous Tumor-Like Lesions | 305 | ||
| Salpingitis Isthmica Nodosa (Fig. 11.25) | 305 | ||
| Torsion | 306 | ||
| Microcalcification | 306 | ||
| Artifacts (Figs. 11.26–11.27) | 306 | ||
| Prolapse (see Chapter 3) | 306 | ||
| References | 306 | ||
| Salpingitis: general features | 306 | ||
| Ligneous salpingitis | 306 | ||
| Arteritis | 306 | ||
| Epithelial hyperplasia: usual type | 306 | ||
| Papillary tubal hyperplasia including secretory cell outgrowths (SCOUTs) | 307 | ||
| Ectopic pregnancy | 307 | ||
| Hydatidiform mole | 307 | ||
| Placental site nodule | 307 | ||
| Arias-Stella reaction | 307 | ||
| Clear cell change of pregnancy | 307 | ||
| Ectopic decidua | 307 | ||
| Endometriosis | 307 | ||
| Mucinous metaplasia | 307 | ||
| Transitional cell and squamous metaplasia | 307 | ||
| Metaplastic papillary ‘tumor’ | 307 | ||
| Rare ectopic tissues | 307 | ||
| Salpingitis isthmica nodosa | 307 | ||
| Torsion | 307 | ||
| Microcalcification | 307 | ||
| Artifacts | 307 | ||
| Tumors of the Fallopian Tube | 308 | ||
| Benign and Borderline Epithelial Tumors | 308 | ||
| Endometrioid Polyp | 308 | ||
| Papilloma, Adenoma, and Cystadenoma | 308 | ||
| Adenofibroma and Cystadenofibroma (Fig. 11.28) | 308 | ||
| Borderline Tumors | 308 | ||
| Carcinomas | 308 | ||
| General and Pathologic Features | 308 | ||
| Clinical features | 308 | ||
| Gross features (Fig. 11.29) | 309 | ||
| Microscopic features (Figs. 11.30–11.34) | 309 | ||
| Differential diagnosis | 311 | ||
| Behavior | 311 | ||
| BRCA-related Tubal Carcinomas and Precursor Lesions (Figs. 11.35–11.36) | 311 | ||
| Serous tubal intraepithelial carcinoma (STIC) | 312 | ||
| Potential precursors of STIC (Fig. 11.37) | 313 | ||
| Differential diagnosis of STIC | 314 | ||
| Malignant Mixed Epithelial–Mesenchymal Tumors | 314 | ||
| Malignant Müllerian Mixed Tumors (MMMTs) | 314 | ||
| Adenosarcoma | 314 | ||
| Pure Mesenchymal Tumors | 314 | ||
| Benign Tumors | 314 | ||
| Sarcomas | 314 | ||
| Adenomatoid Tumor | 315 | ||
| General features | 315 | ||
| Pathological features (Fig. 11.38) | 315 | ||
| Differential diagnosis | 315 | ||
| Germ Cell Tumors | 315 | ||
| Trophoblastic Tumors | 315 | ||
| Choriocarcinoma | 315 | ||
| Placental Site Trophoblastic Tumor and Epithelioid Trophoblastic Tumor | 315 | ||
| Malignant Lymphoma and Leukemia | 315 | ||
| Secondary Tumors | 315 | ||
| From Other Female Genital Tract Sites (Fig. 11.39) | 315 | ||
| From Extragenital Sites | 316 | ||
| References | 316 | ||
| Benign and borderline epithelial tumors | 316 | ||
| Carcinomas: general and pathologic features | 316 | ||
| BRCA-related carcinomas and precursor lesions | 316 | ||
| Malignant müllerian mixed tumors (MMMTs) | 317 | ||
| Adenosarcoma | 317 | ||
| Benign mesenchymal tumors | 317 | ||
| Sarcomas | 317 | ||
| Adenomatoid tumors | 317 | ||
| Germ cell tumors | 318 | ||
| Choriocarcinoma | 318 | ||
| Placental site trophoblastic tumor and epithelioid trophoblastic tumor | 318 | ||
| Malignant lymphoma and leukemia | 318 | ||
| Metastatic tumors | 318 | ||
| Tumor-Like Lesions of the Broad Ligament | 318 | ||
| Embryonic Rests (Figs. 11.40–11.41) | 318 | ||
| Cysts (Fig.11.42) | 318 | ||
| Other Tumor-Like Lesions | 319 | ||
| References | 319 | ||
| Tumors of the Broad Ligament | 319 | ||
| Epithelial Tumors of Müllerian Type (Fig. 11.43) | 319 | ||
| Epithelial Tumors of Definite or Probable Wolffian Origin | 319 | ||
| Papillary Cystadenoma | 319 | ||
| Female Adnexal Tumor of Probable Wolffian Origin (Fig. 11.44) | 320 | ||
| Ependymoma and Primitive Neuroectodermal Tumors | 320 | ||
| Mixed Epithelial–Mesenchymal Tumors (Fig. 11.45) | 321 | ||
| Soft Tissue Tumors | 321 | ||
| Benign | 321 | ||
| Malignant | 321 | ||
| Miscellaneous and Secondary Tumors | 321 | ||
| References | 321 | ||
| Epithelial tumors of müllerian type | 321 | ||
| Papillary cystadenoma | 322 | ||
| Female adnexal tumor of probable wolffian origin | 322 | ||
| Ependymoma and primitive neuroectodermal tumors | 322 | ||
| Mixed epithelial–mesenchymal tumors | 322 | ||
| Benign soft tissue tumors | 322 | ||
| Malignant soft tissue tumors | 322 | ||
| Miscellaneous and secondary tumors | 322 | ||
| 11 Abstracts and Keywords | e11 | ||
| Abstract: | e11 | ||
| Keywords: | e11 | ||
| 12 Tumor-like Lesions of the Ovary | 323 | ||
| Follicular and Stromal Lesions | 324 | ||
| Follicle Cyst | 324 | ||
| Clinical features | 324 | ||
| Pathological features (Figs. 12.1–12.3) | 324 | ||
| Differential diagnosis with unilocular granulosa cell tumor | 324 | ||
| Corpus Luteum Cyst (Figs. 12.4–12.5) | 325 | ||
| Polycystic Ovarian Syndrome (Stein–Leventhal Syndrome) | 325 | ||
| Clinical features | 325 | ||
| Pathological features (Figs. 12.6–12.8) | 325 | ||
| Differential diagnosis | 326 | ||
| Stromal Hyperthecosis | 326 | ||
| Clinical features | 326 | ||
| Pathological features (Figs. 12.9–12.11) | 326 | ||
| 12 Abstracts and Keywords | e12 | ||
| Abstract: | e12 | ||
| Keywords: | e12 | ||
| 13 Surface Epithelial–Stromal Tumors: | 343 | ||
| General Features of Surface Epithelial–Stromal Tumors | 343 | ||
| Classification | 343 | ||
| Grading of Ovarian Carcinomas | 344 | ||
| Clinical Features and Prognostic Factors | 344 | ||
| Hereditary Ovarian Cancer | 345 | ||
| BRCA-related Ovarian Carcinomas | 345 | ||
| HNPPC-related Ovarian Carcinomas | 345 | ||
| References | 346 | ||
| Grading | 346 | ||
| Hereditary ovarian cancer | 346 | ||
| Serous Tumors | 346 | ||
| Benign Serous Tumors | 346 | ||
| Gross features (Figs. 13.1–13.2) | 346 | ||
| Microscopic features (Figs. 13.3–13.4) | 346 | ||
| Differential diagnosis | 347 | ||
| Borderline Serous Tumors | 347 | ||
| Gross features (Fig. 13.5) | 348 | ||
| Usual microscopic features of primary tumors (Figs. 13.6–13.9) | 348 | ||
| Unusual microscopic features of primary tumors (Figs. 13.10–13.17) | 349 | ||
| Microscopic features of implants of serous borderline tumors (Figs. 13.18–13.22) | 352 | ||
| Immunohistochemical and molecular findings | 354 | ||
| Lymph node involvement by serous borderline tumor (Figs. 13.23–13.24) | 354 | ||
| Lymph node involvement by low-grade serous carcinoma in patients with serous borderline tumors | 355 | ||
| Differential diagnosis | 355 | ||
| Prognostic factors in serous borderline tumors | 356 | ||
| Operative findings | 356 | ||
| Features of primary tumors | 356 | ||
| Features of implants, metastases, and recurrences | 356 | ||
| High-grade Serous Carcinomas | 357 | ||
| Clinical features | 357 | ||
| Gross features (Fig. 13.25–13.26) | 357 | ||
| Microscopic features of usual high-grade serous carcinomas (Figs. 13.27–13.34) | 358 | ||
| Microscopic features of BRCA-related high-grade serous carcinomas | 360 | ||
| Immunohistochemistry and molecular findings of low- and high-grade serous carcinomas | 360 | ||
| Differential diagnosis | 360 | ||
| Behavior and prognostic factors | 361 | ||
| Low-grade Serous Carcinomas (Figs. 13.35–13.40) | 362 | ||
| Clinical features | 362 | ||
| Pathological features | 362 | ||
| Behavior | 363 | ||
| References | 363 | ||
| Serous borderline tumors: general features | 363 | ||
| Serous borderline tumors: unusual features, including micropapillary tumors, microinvasion, autoimplants, lymph node involvement, and associated high-grade component | 364 | ||
| High-grade serous carcinoma: general and histological features | 365 | ||
| Serous carcinomas: immunohistochemical and molecular findings | 365 | ||
| Low-grade serous carcinomas | 366 | ||
| Mucinous Tumors | 366 | ||
| General features and histogenesis | 366 | ||
| Clinical features | 367 | ||
| Intestinal-type Mucinous Tumors of Usual Type | 367 | ||
| Gross features (and sampling) of intestinal-type mucinous tumors (Figs. 13.41–13.43) | 367 | ||
| Microscopic features of benign tumors of intestinal type (Figs. 13.44–13.46) | 368 | ||
| Microscopic features of intestinal mucinous borderline tumors (usual type, with intraepithelial carcinoma, and with microinvasion) (Figs. 13.47–13.55) | 369 | ||
| Microscopic features of intestinal-type mucinous carcinomas (Figs. 13.56–13.59) | 371 | ||
| Immunohistochemical and molecular findings in intestinal-type mucinous tumors | 372 | ||
| Differential diagnosis of intestinal-type mucinous tumors | 373 | ||
| Behavior and prognosis of intestinal-type mucinous tumors | 373 | ||
| Teratoma-associated Mucinous Tumors (Fig. 13.60) | 374 | ||
| Endocervical-like Mucinous Borderline Tumors (Figs. 13.61–13.64) | 374 | ||
| Differential diagnosis | 376 | ||
| Endocervical-like Mucinous Carcinomas | 376 | ||
| Mural Nodules in Mucinous Tumors (Figs. 13.65–13.66) | 376 | ||
| References | 377 | ||
| Mucinous tumors: general features | 377 | ||
| Mucinous tumors: immunohistochemistry and molecular findings | 378 | ||
| Teratoma-associated mucinous tumors | 378 | ||
| Endocervical-like mucinous borderline tumors | 378 | ||
| Endocervical-like mucinous carcinomas | 378 | ||
| Mural nodules in mucinous tumors | 378 | ||
| 13 Abstracts and Keywords | e13 | ||
| Abstract: | e13 | ||
| Keywords: | e13 | ||
| 14 Surface Epithelial–Stromal Tumors: | 380 | ||
| Endometrioid Epithelial Tumors | 380 | ||
| General features | 380 | ||
| Gross features (Fig. 14.1) | 381 | ||
| Microscopic features of benign tumors (Figs. 14.2–14.4) | 381 | ||
| Microscopic features and behavior of borderline endometrioid tumors (Fig. 14.5) | 382 | ||
| Typical microscopic features of endometrioid carcinomas (Figs. 14.6–14.10) | 382 | ||
| Uncommon findings (Figs. 14.11–14.15) | 384 | ||
| Immunohistochemical and molecular findings | 385 | ||
| Differential diagnosis | 385 | ||
| Behavior | 387 | ||
| References | 387 | ||
| Endometrioid carcinomas: general features | 387 | ||
| Endometrioid carcinomas: unusual findings and subtypes | 387 | ||
| Synchronous uterine and ovarian endometrioid carcinomas | 388 | ||
| Malignant Mesodermal Mixed Tumor | 388 | ||
| General and gross features | 388 | ||
| Microscopic features (Fig. 14.16) | 388 | ||
| Differential diagnosis | 388 | ||
| Spread and prognosis | 389 | ||
| References | 389 | ||
| Adenosarcoma (Figs. 14.17–14.19) | 389 | ||
| Clinical and pathological features | 389 | ||
| Differential diagnosis | 390 | ||
| Spread and prognosis | 390 | ||
| References | 390 | ||
| Endometrioid Stromal Sarcoma | 390 | ||
| General features | 390 | ||
| Pathological features (Fig. 14.20) | 390 | ||
| Differential diagnosis | 391 | ||
| Spread and prognosis | 391 | ||
| References | 391 | ||
| Clear Cell Tumors | 392 | ||
| General features | 392 | ||
| Gross features (Fig. 14.21) | 392 | ||
| Microscopic features of benign and borderline clear cell tumors (Figs. 14.22–14.23) | 392 | ||
| Microscopic features of clear cell carcinomas (Figs. 14.24–14.30) | 393 | ||
| Immunohistochemical and molecular findings in clear cell carcinomas | 395 | ||
| Differential diagnosis | 395 | ||
| Behavior and prognostic factors | 396 | ||
| References | 397 | ||
| Clear cell carcinomas: morphologic, immunohistochemical, and molecular findings | 397 | ||
| Clear cell carcinomas: clinical and prognostic features, including grading | 397 | ||
| Transitional Cell Tumors (Figs. 14.31–14.39) | 398 | ||
| General features | 398 | ||
| Gross features of benign Brenner tumor (Fig. 14.31) | 399 | ||
| Gross features of other transitional cell tumors (Fig. 14.34) | 400 | ||
| Microscopic features of benign Brenner tumor (Figs. 14.32–14.33) | 400 | ||
| Microscopic features of borderline Brenner tumor (Fig. 14.35) | 400 | ||
| Microscopic features of malignant Brenner tumor (Fig. 14.36) | 400 | ||
| Microscopic features of transitional cell carcinoma (Figs. 14.37–14.39) | 400 | ||
| Immunohistochemical and molecular findings | 400 | ||
| Differential diagnosis | 401 | ||
| Spread and prognosis | 401 | ||
| References | 401 | ||
| Squamous Cell Tumors | 402 | ||
| 14 Abstracts and Keywords | e14 | ||
| Abstract: | e14 | ||
| Keywords: | e14 | ||
| 15 Germ Cell Tumors of the Ovary | 408 | ||
| General Features | 408 | ||
| Primitive Germ Cell Tumors (Nonteratomatous) | 409 | ||
| Dysgerminoma | 409 | ||
| Clinical features | 409 | ||
| Gross pathological findings (Fig. 15.1) | 409 | ||
| Microscopic findings (Figs. 15.2–15.8) | 409 | ||
| Differential diagnosis | 411 | ||
| Prognosis | 412 | ||
| Yolk Sac Tumor | 412 | ||
| Clinical features | 412 | ||
| Gross features (Figs. 15.9–15.10) | 412 | ||
| Typical microscopic features (Figs. 15.11–15.15) | 412 | ||
| Microscopic features of variant patterns (Figs. 15.16–15.20) | 414 | ||
| Polyvesicular vitelline | 414 | ||
| Hepatoid | 415 | ||
| Glandular | 415 | ||
| Differential diagnosis | 415 | ||
| Prognosis | 415 | ||
| Embryonal Carcinoma | 415 | ||
| Clinical features | 415 | ||
| Pathological features (Figs. 15.21–15.22) | 416 | ||
| Differential diagnosis | 416 | ||
| Prognosis | 416 | ||
| Polyembryoma (Figs. 15.23–15.24) | 416 | ||
| Nongestational Choriocarcinoma (Figs. 15.25–15.26) | 417 | ||
| Differential diagnosis | 418 | ||
| Prognosis | 418 | ||
| Mixed Primitive Germ Cell Tumors | 418 | ||
| References | 418 | ||
| Dysgerminoma | 418 | ||
| Yolk sac tumor | 418 | ||
| Embryonal carcinoma | 419 | ||
| Polyembryoma | 419 | ||
| Choriocarcinoma | 419 | ||
| Mixed primitive germ cell tumors | 419 | ||
| Teratomas (other than Monodermal) | 419 | ||
| Dermoid Cyst (Mature Cystic Teratoma) | 419 | ||
| Clinical features | 419 | ||
| Gross pathological features (Figs. 15.27–15.28) | 419 | ||
| Microscopic pathological features (Figs.15.29–15.33) | 420 | ||
| Differential diagnosis | 420 | ||
| Mature Solid Teratoma | 421 | ||
| Fetiform Teratoma (Homunculus) | 422 | ||
| Immature Teratoma | 422 | ||
| Clinical features | 422 | ||
| Pathological features (Figs. 15.34–15.38) | 422 | ||
| Differential diagnosis | 423 | ||
| Prognosis | 424 | ||
| References | 424 | ||
| Mature cystic teratoma (dermoid cyst) | 424 | ||
| Mature solid teratoma | 424 | ||
| Fetiform teratoma (homunculus) | 424 | ||
| Immature teratoma | 424 | ||
| Monodermal Teratomas | 425 | ||
| Struma Ovarii | 425 | ||
| Clinical features | 425 | ||
| Pathological features (Figs. 15.39–15.47) | 425 | ||
| Differential diagnosis | 427 | ||
| Struma-derived Carcinomas (Figs. 15.48–15.49) | 427 | ||
| Insular Carcinoid | 428 | ||
| Clinical features | 428 | ||
| Pathological features (Figs. 15.50–15.52) | 428 | ||
| Differential diagnosis | 429 | ||
| Behavior | 429 | ||
| Trabecular Carcinoid | 429 | ||
| Clinical features and behavior | 429 | ||
| Pathological features | 430 | ||
| Differential diagnosis | 430 | ||
| Strumal Carcinoid | 430 | ||
| Clinical features and behavior | 430 | ||
| Pathological features (Figs. 15.53–15.54) | 430 | ||
| 15 Abstracts and Keywords | e15 | ||
| Abstract: | e15 | ||
| Keywords: | e15 | ||
| 16 Sex Cord−Stromal and Steroid Cell Tumors of the Ovary | 439 | ||
| Sex Cord−Stromal Tumors | 439 | ||
| Granulosa Cell Tumors | 439 | ||
| Adult Granulosa Cell Tumor | 439 | ||
| General features | 439 | ||
| Gross features (Fig. 16.1) | 440 | ||
| Typical microscopic features (Figs. 16.2–16.6) | 440 | ||
| Uncommon or rare features (Fig. 16.7) | 440 | ||
| Immunohistochemical and molecular findings | 442 | ||
| Differential diagnosis | 442 | ||
| Behavior | 444 | ||
| Prognostic factors | 444 | ||
| Juvenile Granulosa Cell Tumor | 445 | ||
| General features | 445 | ||
| Pathologic features (Figs. 16.8–16.13) | 445 | ||
| Differential diagnosis | 446 | ||
| Behavior | 447 | ||
| Tumors in the Fibroma–Thecoma Group | 447 | ||
| Fibroma and Cellular Fibroma | 447 | ||
| Clinical features | 447 | ||
| Gross features (Fig. 16.14) | 447 | ||
| Microscopic features (Figs. 16.15–16.19) | 447 | ||
| 16 Abstracts and Keywords | e16 | ||
| Abstract: | e16 | ||
| Keywords: | e16 | ||
| 17 Miscellaneous Primary Ovarian Tumors | 470 | ||
| Small Cell Carcinoma of Hypercalcemic Type | 470 | ||
| Clinical features | 470 | ||
| Gross and microscopic features (Figs. 17.1–17.7) | 471 | ||
| Immunohistochemical, ultrastructural, and flow cytometric findings | 472 | ||
| Differential diagnosis (Table 17.1) | 472 | ||
| Behavior and prognosis | 473 | ||
| References | 473 | ||
| Tumors of Probable Wolffian Origin | 473 | ||
| Clinical features | 473 | ||
| Pathological findings | 474 | ||
| Differential diagnosis | 474 | ||
| Prognosis | 474 | ||
| References | 474 | ||
| Tumors of the Rete | 474 | ||
| Clinical features | 474 | ||
| Pathological findings (Fig. 17.8) | 474 | ||
| 17 Abstracts and Keywords | e17 | ||
| Abstract: | e17 | ||
| Keywords: | e17 | ||
| 18 Metastatic Tumors of the Ovary (including Pseudomyxoma Peritonei, Hematolymphoid Neoplasms, and Tumors with Functioning Stroma) | 482 | ||
| General Features (Figs. 18.1–18.8) | 483 | ||
| 18 Abstracts and Keywords | e18 | ||
| Abstract: | e18 | ||
| Keywords: | e18 | ||
| 19 Endometriosis and Lesions of the Secondary Müllerian System | 513 | ||
| References | 514 | ||
| Endometriosis | 514 | ||
| Clinical features | 514 | ||
| Gross findings (Figs. 19.1–19.3) | 514 | ||
| Typical microscopic findings (Figs. 19.4–19.14) | 515 | ||
| Microscopic findings causing diagnostic problems including underdiagnosis (Figs. 19.15–19.28) | 518 | ||
| Differential diagnosis | 522 | ||
| Atypical endometriosis and endometriosis-associated tumors (Figs. 19.29–19.30) | 522 | ||
| References | 524 | ||
| General | 524 | ||
| Atypical endometriosis and endometriosis-related tumors | 524 | ||
| Peritoneal endometrioid tumors unrelated to endometriosis | 525 | ||
| Peritoneal Serous Lesions | 525 | ||
| Endosalpingiosis (Fig. 19.31) | 525 | ||
| Clinical features | 525 | ||
| Pathologic findings | 526 | ||
| Differential diagnosis | 526 | ||
| Peritoneal Serous Borderline Tumors (Figs. 19.32–19.33) | 526 | ||
| Clinical features | 527 | ||
| Pathological features | 527 | ||
| Behavior | 527 | ||
| Low-grade Peritoneal Serous Carcinomas, including Psammocarcinomas (Fig. 19.34) | 527 | ||
| High-grade Peritoneal Serous Carcinomas | 528 | ||
| Differential diagnosis | 528 | ||
| References | 528 | ||
| Endosalpingiosis | 528 | ||
| Peritoneal serous borderline tumors | 529 | ||
| Low-grade peritoneal serous carcinomas, including psammocarcinomas | 529 | ||
| High-grade peritoneal serous carcinomas | 529 | ||
| Peritoneal Mucinous Lesions | 529 | ||
| Endocervicosis (including Müllerianosis) (Figs. 19.35–19.36) | 529 | ||
| Differential diagnosis | 529 | ||
| Retroperitoneal Mucinous Tumors (Figs. 19.37–19.38) | 530 | ||
| References | 530 | ||
| Endocervicosis | 530 | ||
| Retroperitoneal mucinous tumors | 531 | ||
| Peritoneal Transitional, Squamous, Clear Cell, and Other Rare Lesions (Figs. 19.39–19.41) | 531 | ||
| References | 531 | ||
| Subperitoneal Mesenchymal Lesions | 532 | ||
| Peritoneal Decidual Reaction | 532 | ||
| Clinical and operative findings | 532 | ||
| Microscopic findings (Figs. 19.42–19.43) | 532 | ||
| Disseminated Peritoneal Leiomyomatosis | 532 | ||
| Clinical findings | 532 | ||
| Pathological features (Figs. 19.44–19.46) | 533 | ||
| Behavior | 533 | ||
| Histogenesis | 533 | ||
| References | 533 | ||
| Ectopic decidua | 533 | ||
| Disseminated peritoneal leiomyomatosis | 533 | ||
| Retroperitoneal Lymph Node Lesions | 534 | ||
| Benign Glands of Müllerian Type | 534 | ||
| Clinical features | 534 | ||
| Pathologic findings (Figs. 19.47–19.48) | 534 | ||
| Differential diagnosis | 535 | ||
| Primary Intranodal Serous Borderline Tumors and Low-grade Serous Carcinoma (see Chapter 13) | 535 | ||
| Decidua (Fig. 19.49) | 535 | ||
| Leiomyomatosis (Fig. 19.50) | 535 | ||
| 19 Abstracts and Keywords | e19 | ||
| Abstract: | e19 | ||
| Keywords: | e19 | ||
| 20 Tumor-like Lesions and Tumors of the Peritoneum (Excluding Müllerian Lesions) | 537 | ||
| Tumor-Like Lesions | 537 | ||
| Inflammatory and Reparative Lesions | 537 | ||
| Granulomatous Peritonitis (Figs. 20.1–20.4) | 537 | ||
| Nongranulomatous Histiocytic Lesions (Figs. 20.5–20.8) | 538 | ||
| Peritoneal Fibrosis (Figs. 20.9–20.10) | 539 | ||
| Mesothelial Lesions | 541 | ||
| Mesothelial Hyperplasia (Figs. 20.11–20.17) | 541 | ||
| Differential diagnosis | 542 | ||
| Peritoneal Inclusion Cysts (Figs. 20.18–20.22) | 542 | ||
| Unilocular PICs | 542 | ||
| Multilocular PICs | 543 | ||
| Miscellaneous Lesions | 544 | ||
| Splenosis (Fig. 20.23) | 544 | ||
| Trophoblastic Implants (Fig. 20.24) | 544 | ||
| Infarcted Appendix Epiploica (Fig. 20.25) | 544 | ||
| Other Tumor-like Lesions | 545 | ||
| References | 545 | ||
| Inflammatory and reparative lesions | 545 | ||
| Mesothelial hyperplasia | 545 | ||
| Multilocular PICs | 546 | ||
| Splenosis | 546 | ||
| Trophoblastic implants | 546 | ||
| Infarcted appendix epiploica | 546 | ||
| Other tumor-like lesions | 546 | ||
| Tumors | 546 | ||
| Mesotheliomas | 546 | ||
| Adenomatoid Tumor | 546 | ||
| Well-differentiated Papillary Mesothelioma (Fig. 20.26) | 546 | ||
| Malignant Mesothelioma | 547 | ||
| Clinical features | 547 | ||
| Typical pathological findings (Figs. 20.27–20.32) | 547 | ||
| Unusual histologic variants and findings (Figs. 20.28–20.34) | 548 | ||
| Differential diagnosis | 549 | ||
| Behavior and prognostic factors | 550 | ||
| Intra-Abdominal Desmoplastic Small Round-Cell Tumor | 550 | ||
| Clinical features | 550 | ||
| Pathological features (Figs. 20.35–20.37) | 550 | ||
| Immunohistochemical and ultrastructural features | 551 | ||
| Differential diagnosis | 551 | ||
| Mesenchymal Tumors | 551 | ||
| Solitary Fibrous Tumor | 551 | ||
| Inflammatory Myofibroblastic Tumor | 551 | ||
| Calcifying Fibrous Tumor | 552 | ||
| Omental–Mesenteric Myxoid Hamartoma | 552 | ||
| Sarcomas | 552 | ||
| Rare Primary Tumors | 552 | ||
| Metastatic Tumors (Figs. 20.38–20.39) | 552 | ||
| References | 553 | ||
| Well-differentiated papillary mesothelioma | 553 | ||
| Malignant mesothelioma: general features | 553 | ||
| Malignant mesothelioma: immunohistochemistry | 553 | ||
| Intra-abdominal desmoplastic small round cell tumor | 554 | ||
| Solitary fibrous tumor | 554 | ||
| Inflammatory myofibroblastic tumor | 554 | ||
| Calcifying fibrous tumor | 554 | ||
| Omental–mesenteric myxoid hamartoma | 554 | ||
| Sarcomas | 554 | ||
| Rare primary tumors | 554 | ||
| Metastatic tumors | 554 | ||
| 20 Abstracts and Keywords | e20 | ||
| Abstract: | e20 | ||
| Keywords: | e20 | ||
| INDEX | 555 | ||
| A | 555 | ||
| B | 556 | ||
| C | 556 | ||
| D | 557 | ||
| E | 557 | ||
| F | 559 | ||
| G | 559 | ||
| H | 560 | ||
| I | 560 | ||
| J | 560 | ||
| K | 560 | ||
| L | 560 | ||
| M | 561 | ||
| N | 562 | ||
| O | 562 | ||
| P | 563 | ||
| R | 564 | ||
| S | 564 | ||
| T | 566 | ||
| U | 566 | ||
| V | 567 | ||
| W | 568 | ||
| X | 568 | ||
| Y | 568 | ||
| Z | 568 |